Virus Weekly articles from January 2004

Virus Weekly archives from January 2004

De novo methylation patterns are common to papillomavirus DNA.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- According to published research from the United States, "the biological activities of the papillomavirus E2 protein in transcription, replication, and maintenance of the papillomavirus genome rely on...

Modified adeno-associated virus type 2 circumvents human antibodies.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Modified adeno-associated virus type 2 circumvents human antibodies. "The high prevalence of human serum antibodies against adeno-associated virus type 2 (AAV) vectors represents a potential...

Dengue 4 virus glycoprotein induces resistance to Dengue 4 virus.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- The carboxy-terminally truncated Dengue 4 virus envelope glycoprotein expressed in Pichia pastoris induced neutralizing antibodies and resistance to Dengue 4 virus challenge in mice. "We have...

Study: Coronavirus part bird, part mammal.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Severe acute respiratory syndrome (SARS) is formed by a combination of mammalian and avian viruses, says a new study from the University of Toronto. The study, published in the January 2004 issue of...

Adenovirus serotype 35 vector has an attractive distribution profile.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Adenovirus serotype 35 vector has an attractive distribution profile. "We have recently developed a replication-defective, recombinant adenovirus (Ad) vector composed of the whole Ad serotype 35...

Lassa virus signal peptide acts as a trans-acting maturation factor.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Scientists have identified a Lassa virus glycoprotein signal peptide that functions as a trans-acting maturation factor. According to a study from Germany, "Lassa virus glycoprotein is translated...

Attenuated adenovirus induces thrombocytopenia in rhesus monkeys.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Intravenous administration of replication-incompetent adenovirus to rhesus monkeys induces thrombocytopenia by increasing in vivo platelet clearance. "A replication-incompetent adenovirus vector was...

Adenovirus proteinase is inhibited by NO from NONOates; viral infection lowered.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Adenovirus proteinase is inhibited by NO from NONOates; viral infectivity lowered. "Nitric oxide (NO) is an antiviral effector of the innate immune system, but few of the viral targets of NO have...

A new heterocyclic HCV replicon RNA synthesis inhibitor has distinct kinetics.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- A new heterocyclic HCV replicon RNA synthesis inhibitor has distinct kinetics. "Recently, a benzo-1,2,4-thiadiazine was shown to be a potent, specific inhibitor of the hepatitis C virus (HCV) RNA...

Pediatric measles-like rash may be separate or coinciding HHV-6, HHV-7 infection.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Pediatric measles-like rash may be separate or coinciding human herpesvirus-6 and/or 7 (HHV-6 and/or HHV-7) primary infection. According to a study from Brazil, "we investigated primary HHV-6,...

Patient and viral factors correlate with pediatric response to lamivudine.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Patient and viral factors correlate with pediatric response to lamivudine. "Despite the recent approval of lamivudine for the treatment of children with chronic hepatitis B virus (HBV) infection,...

The Chemagic viral DNA/RNA kit improves viral extraction.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- The Chemagic viral DNA/RNA kit improves viral extraction. "The Chemagic viral DNA/RNA kit was evaluated for extraction of cytomegalovirus (CMV), hepatitis B virus (HBV), and hepatitis G virus (HGV)...

Antiviral pronucleotides improved through cycloSal system.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- The cycloSal system can be used to improve the efficacy of antiviral pronucleotide agents. "Pronucleotides represent a promising alternative to improve the biological activity of nucleoside analogs...

HIV RNase H activity characterization leads to novel anti-HIV agents.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- The activity of HIV RNase H has been elucidated, and this information has been used to develop novel anti-HIV agents "Human immunodeficiency virus (HIV) RNase H activity is essential for the...

Markovian model can aid anti-HIV drug design.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- A novel Markovian model may aid the design of antiretroviral agents. "The design of novel anti-HIV compounds has now become a crucial area for scientists working in numerous interrelated fields of...

Novel computational approach aids HIV protease inhibitor design.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- A novel design method may improve the development of HIV protease inhibitors. In a recent study, scientists in Belgium "developed a computational approach in which an inhibitor's strength is...

2003 begins with SARS, ends with flu.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- A dangerous respiratory illness that seemed to spring from nowhere and rapidly spread was the biggest medical news of 2003. No, it wasn't the flu. It was SARS. The end of 2003 saw hundreds of...

Lentiviral vectors efficiently transduce HLECs.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Lentiviral vectors can efficiently deliver therapeutic genes to cultured HLECs. "Endothelial cells play multiple roles in pathophysiologic processes and are increasingly being recognized as target...

Recombinant DNA model enables HIV-2 gene analysis.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- A recombinant DNA model enables extensive genetic analysis of HIV-2. "Human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2) differ in their pathogenic mechanisms as evidenced by lower rate...

"Mega-PCR" assay lowers detection limit of HIV DNA.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- A novel "mega-PCR" assay can find previously undetectable levels of HIV DNA in blood samples. In a recent study from Switzerland, "An internally controlled high-input PCR method, termed HIV-1...

FIV induces phenotypical changes in CD8 cells.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- The feline version of HIV induces phenotypical changes in CD8 - but not CD4 - cells. "It is well documented that several cell surface molecules of T lymphocytes are altered by immune activation,"...

Low HDMT scores may not indicate HIV neurodegeneration.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Low HDMT scores do not necessarily indicate HIV neurodegeneration. According to a study from the United States, "There is an emergent need for base rate data on symptom validity tests (SVTs) in...

Pneumocystis carinii mt LSU rRNA gene in SIV-infected macaques examined.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- The P. carinii mt LSU rRNA gene has been characterized in SIV-infected monkeys. In a recent study from the United States, "The nucleotide sequences of a segment of the Pneumocystis mitochondrial...

HIV-exposed but uninfected IDUs have heightened NK-cell activity.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Injecting drug users who remain HIV-negative after extensive exposure have elevated levels of natural killer (NK)-cell activity. In a recent study, scientists in France "addressed the role of...

Viral replication does not lead to SIV disease progression in sooty mangabeys.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Surprisingly, viral replication in SIV-infected sooty mangabeys does not lead to disease progression. "Simian immunodeficiency virus SIVsm causes an asymptomatic infection in its natural host, the...

HIV Tat interacts with Notch protein EGF-like repeats and the EGF precursor.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- HIV Tat interacts with Notch protein EGF-like repeats and the EGF precursor. In a recent study from Israel, by "employing the yeast two-hybrid system, the Tat protein of the human immunodeficiency...

Molecular assay enables accurate measure of CCR5 mRNA.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- A novel molecular assay provides a sensitive and accurate measure of CCR5 mRNA. According to published research from the United States, "CCR5, a beta-chemokine receptor, plays an important role in...

Growth hormone treatment can improve NK-cell function.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Growth hormone therapy can improve NK-cell function in HIV patients. "Previous studies have shown that human natural killer (NK) cells are lost from the periphery and are functionally suppressed...

Mediators of protease inhibitor-induced bone resorption identified.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- The molecular mediators of HIV protease inhibitor-induced bone damage have been identified. "Accelerated bone resorption leading to osteopenia and osteoporosis has been noted in human...

Modified p24 antigen assay useful for disease monitoring in HIV patients.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- A modified p24 antigen assay may simplify disease monitoring in HIV patients. "HIV-1 RNA has become the standard for monitoring antiretroviral therapies," immunologists in Switzerland explained....

Nelfinavir does not cause reproductive toxicity in rats.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- The antiretroviral agent nelfinavir does not affect reproductive performance or embryonic development in a murine model of HIV treatment. In a study from the United States, "The potential for...

Prophylactic antiretroviral treatment reduces T-cell apoptosis.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Prophylactic antiretroviral treatment significantly reduces T-cell apoptosis. "It has been proposed that antiretroviral therapies (ART) possess both antiviral and immunomodulatory activities when...

Small-molecule CCR5 inhibitor effective in macaques.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- A small-molecule CCR5 inhibitor significantly reduces viremia in macaques infected with the simian version of HIV. "Human immunodeficiency virus type 1 (HIV-1) fuses with cells after sequential...

Thymosin alpha1 shows promise for improving immune recovery.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Thymosin alpha1 appears to improve immune recovery in HIV patients. According to published research from Singapore, "To study the safety and efficacy of thymosin alpha1 in stimulating immune...

Clinical trials begin for Procleix Ultrio assay.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Chiron Corporation (CHIR) and Gen-Probe Incorporated (GPRO) announced that clinical trials of the Procleix Ultrio Assay, for the simultaneous detection of HIV-1, hepatitis C virus (HCV) and hepatitis B...

A key hepatitis C virus protein modulates apoptosis in liver cells.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- A key hepatitis C virus protein modulates apoptosis in liver cells. "To analyze the influence of hepatitis C virus nonstructural protein 5A (NS5A) on apoptosis, we established Huh7 cells that stably...

Hepatitis A vaccine does not promote atherogenesis in murine model.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- The hepatitis A vaccine did not promote atherogenesis in a murine model. According to recent research from the United States, "Our laboratory demonstrated that seropositivity to hepatitis A virus...

New or old Pap smears can be destained and used to test for HSV-2 viral DNA.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- New or old Pap smears can be destained and used to test for herpes simplex 2 viral DNA. "Papanicolaou-stained cervicovaginal smears from six patients with herpes simplex virus (HSV) infection were...

Immunotherapy company provides update on late-stage adjuvant programs.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Corixa Corp. (CRXA) provided an update on two late stage potential products containing Corixa's MPL adjuvant featured during GlaxoSmithKline's (GSK) recent Research & Development Meeting with investors....

Human enterovirus 71 contains a type I IRES element similar to other enterovirus.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Human enterovirus 71 (EV71) contains a noncoding region with a type I IRES element similar to other enterovirus genomes. According to a study from the United States, "human EV71 is a member of the...

Molecular assay detects norovirus, Sapovirus and astrovirus.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- A novel molecular assay can detect three pathogenic enteric viruses. In a recent study from Japan, "A reverse transcription (RT) single-round multiplex polymerase chain reaction (smPCR) assay was...

Among high-risk adults, flu shots less likely for blacks than whites.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Adults who are at high risk from flu complications are strongly urged to get an influenza vaccination this year, yet a study shows a racial disparity in the response. In an analysis of data from...

CDC activates center to deal with flu.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- America's top health agency has activated its emergency operations center and has established response teams to assist states with the country's flu outbreak, federal officials have announced. The...

Company reports positive preclinical data against variant influenza strains.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- ID Biomedical reported it has data demonstrating protection against variant strains of influenza. Results from preclinical experiments performed by ID Biomedical scientists and recently published...

Integra syringe maximizes current flu vaccination supply.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- A 10-dose vial of flu vaccine can provide 11 vaccinations when delivered with a Becton, Dickinson and Company (BD) Integra Syringe, BD advises healthcare providers. The syringe is designed with a...

New flu test for physician offices launched.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Meridian Bioscience, Inc., (VIVO) announced it has begun marketing a new physician's office influenza A&B test. According to Meridian, this rapid test is simple enough to be performed in...

Scientists agonized over choosing less-than-perfect flu vaccine.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Late last winter, a committee of vaccine experts designing this season's flu shot considered their choices. They had two, and both seemed bad. Should they stick with last year's formula, even though...

Scientists warn of coming flu pandemic.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- As bad as this year's flu season is, it hasn't brought the worldwide outbreak known as a pandemic. But experts warn that a pandemic is coming, it's just a question of when. "It's going to happen,"...

Shipment of about 43M doses of influenza vaccine completed.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Aventis announced that the company has completed shipment of approximately 43 million doses of its influenza vaccine (Fluzone, Influenza Virus Vaccine) to customers for the 2003-04 influenza season. ...

Some New Jersey insurers expand coverage to include nasal flu vaccine.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Several insurance companies in New Jersey said they will cover costs for a new nasal flu vaccine during this flu season, according to a report. AmeriHealth, Aetna, Oxford Health Plans, and Horizon...

AmeriHealth to cover FluMist due to vaccine shortage.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- In response to the reported shortage of injectible flu vaccines, AmeriHealth announced that for the remainder of this flu season, the insurer will expand its coverage of flu vaccines to include the...

Cross-reactive H1N1 antibody responses to influenza vaccine reported.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Cross-reactive H1N1 antibody responses to a live attenuated influenza vaccine in children have implication for selection of vaccine strains. According to published research from the United States,...

Emerging viral diseases present opportunities for niche diagnostics.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- A host of emerging viral infections is providing a market for niche manufacturers of new diagnostic tests, according to a new study released from Kalorama Information. In both human and animal...

AVR118 suppresses progression of disease in animal model.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Advanced Viral Research Corp. (ADVR) announced that administration of its novel immunomodulator AVR118 (formerly known as Product R) in animals with induced experimental allergic encephalomyelitis (EAE)...

Diffusion imaging and proton MRI can aid HSE diagnosis in AIDS patients.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Several magnetic resonance imaging (MRI) techniques are useful for diagnosing HSE in AIDS and other patients. Scientists in Germany described a "case of pathologically proved atypical herpes...

Researchers warn pregnant women to be wary of flu outbreak.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Pregnant women in the U.S. should be particularly wary of the current flu outbreak, researchers caution. Women who experience fever during their second trimester of pregnancy have been found to be...

David Arkowitz becomes CFO.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Idenix Pharmaceuticals, Inc., announced the appointment of David Arkowitz to the position of CFO. Arkowitz has more than 13 years of experience in financial leadership positions at Merck & Co,...

Research suggests more needs to be done to protect at-risk infants from RSV.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- New clinical data provide additional evidence that premature (i.e., less than or equal to 35 weeks gestational age [wGA]) infants are at elevated risk for respiratory syncytial virus (RSV)-related...

Compound for influenza tests positive in preliminary in vitro SARS study.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- The Quigley Corporation (QGLY) announced that an independent in vitro study conducted by Retroscreen Virology Limited found that a Quigley test compound previously tested on the influenza virus showed...

Non-viral factors play key role in SARS severity.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Non-viral factors - more so than viral genomics - play key roles in determining the severity and pathogenicity of severe acute respiratory syndrome (SARS). According to recent research from China,...

Outbreak in Beijing spread rapidly, was controlled fairly quickly.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Improving triage in hospitals and dissemination of information to the public helped bring a rapid resolution to the spread of severe acute respiratory syndrome (SARS) in Beijing in early 2003, according...

Preliminary report suggests combination therapy may help treat SARS.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- A preliminary study suggests that use of a combination of corticosteroids and interferon may have a role in treatment of severe acute respiratory syndrome (SARS). SARS is characterized by fever,...

Spilled lab sample likely infected Taiwanese scientist.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- A spilled test tube containing a SARS sample likely infected a medical researcher who wasn't wearing gloves or a gown, the World Health Organization claimed when the scientist was diagnosed as the first...

Pharmaceutical and USAMRIID collaborate on molecule-screening program.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Kemin Pharma announced the formation of a collaborative molecule-screening program with the U.S. Army Medical Research Institute for Infectious Diseases (USAMRIID). Under the terms of the...

Amotosalen-treated T cells prevent CMV infection without inducing GVHD.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- T cells treated with amotosalen prevent CMV infection in murine stem-cell transplant recipients, without triggering graft-versus-host reactions "Infusion of donor antiviral T cells can provide...

Immune-mediated inner ear disease has recurrences like some autoimmune diseases.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Immune-mediated inner ear disease (IMIED) behaves recurrently like some autoimmune diseases. "Since the McCabe report, growing indirect evidence has accumulated to indicate the implication of immune...

Data on next-generation VEGF cancer agent presented at ASH.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- The first in the next generation of vascular endothelial growth factor (VEGF) inhibiting agents - those that employ a three-prong approach to inhibiting tumor growth - can be administered safely in a...

Double-stranded adeno-associated virus vectors produce rapid transduction.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Double-stranded adeno-associated virus vectors produce rapid transfection. According to recent research published in the journal Gene Therapy, "adeno-associated virus (AAV) is a promising gene...

South American dengue-1 viral genotypes determined.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Dengue-1 viral genotypes in South America have been elucidated. In a recent study, virologists in the United States "determined the complete coding sequences of six dengue-1 (DEN-1) viruses...

Analysis of iridoviruses based on protein and DNA sequences reported.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Researchers report the results of a cladistic analysis of iridoviruses based on protein and DNA sequences in a recent issue of the Archives of Virology. According to recent research from China,...

Effects of GBV-C co-infection on HIV progression reviewed.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- The effects of GB virus type C hepatitis G virus (GBV-C) co-infection on HIV progression have been reviewed. GBV-C "is a common virus that does not appear to cause disease," scientists in the...

Purdue biologists expose the inner workings of viral machine.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Purdue University scientists have peered inside a virus and visualized for the first time how it produces and exports genetic materials into a host cell, an advance in fundamental research that also...

Short hairpin RNAs inhibit hepatitis B virus replication.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Short hairpin RNAs inhibit hepatitis B virus replication. "The major challenges for anti-hepatitis B Virus (HBV) therapy are the low efficacy of current drugs and the occurrence of drug resistant...

Tagged baculovirus capsids are new tools for analyzing transduction.
January 6, 2004... 2004 JAN 6 - (NewsRx.com & NewsRx.net) -- Tagged baculovirus capsids are new tools for analyzing transduction. "Baculoviruses are enveloped insect viruses that can carry large quantities of foreign DNA in their genome. Baculoviruses have...

Anti-HIV alkaloids isolated from Monanchora sponge.
January 13, 2004... 2004 JAN 13 - (NewsRx.com & NewsRx.net) -- Novel antiretroviral compounds have been isolated from sponges. In a recent study from the United States, "Two new polycyclic guanidine alkaloids, crambescidin 826 (1) and dehydrocrambine A (2),...

Baseline values of herpes zoster among children and adolescents determined.
January 13, 2004... 2004 JAN 13 - (NewsRx.com & NewsRx.net) -- The baseline value of herpes zoster among children and adolescents was determined to allow monitoring of an increase in herpes zoster incidence following varicella vaccination. According to recent...

Herpesvirus 8 and Epstein-Barr virus seropositivity among children compared.
January 13, 2004... 2004 JAN 13 - (NewsRx.com & NewsRx.net) -- Scientists published a comparison of human herpesvirus 8 and Epstein-Barr virus seropositivity among children in areas endemic and non-endemic for Kaposi sarcoma in a recent issue of the Journal of...

Oral cavity is a reservoir of HPVs in childhood.
January 13, 2004... 2004 JAN 13 - (NewsRx.com & NewsRx.net) -- Researchers find that the oral cavity is a reservoir of HPVs in childhood where later HPV-associated diseases may develop. "The purpose of this study was to determine the frequency of human...

Bat lyssaviruses from Central Asia categorized.
January 13, 2004... 2004 JAN 13 - (NewsRx.com & NewsRx.net) -- Investigators have classified the phylogenetic relationships among bat lyssaviruses from Central Asia according to N, P, and G gene sequences. "Bat lyssaviruses Aravan and Khujand were isolated in...

Company files additional data with FDA on new Reveal Rapid HIV-1 Antibody Test.
January 13, 2004... 2004 JAN 13 - (NewsRx.com & NewsRx.net) -- MedMira, Inc., (MIR) announced that it has successfully completed the clinical requirements set forth by the U.S. Food and Drug Administration (FDA) for a new version of the Reveal Rapid HIV-1 Antibody...

Adenovirus proteinase interactions with viral DNA and peptide reported.
January 13, 2004... 2004 JAN 13 - (NewsRx.com & NewsRx.net) -- Researchers describe the specific interactions of the adenovirus proteinase with the viral DNA, an 11-amino-acid viral peptide, and the cellular protein actin in a recent issue of Cellular and...

Adenovirus requires active proteasomes to promote late gene expression.
January 13, 2004... 2004 JAN 13 - (NewsRx.com & NewsRx.net) -- Adenovirus E4-34kDa requires active proteasomes to promote late gene expression. "A complex of the Adenovirus (Ad) early region 1b 55-kDa protein (E1b-55kDa) and the early region 4 ORF6 34-kDa...

Intestinal intussusception associated with adenovirus in Mexican children.
January 13, 2004... 2004 JAN 13 - (NewsRx.com & NewsRx.net) -- Intestinal intussusception is associated with adenovirus infection in Mexican children. "Formalin-fixed intestinal tissue specimens from 12 Mexican pediatric patients with intussusception were...

Companies form joint venture for R&D of infectious diseases diagnostics.
January 13, 2004... 2004 JAN 13 - (NewsRx.com & NewsRx.net) -- Spectral Diagnostics Inc. (SDI) and a group of investors led by the Canadian Medical Discoveries Fund Inc. (CMDF) announced entering into agreements, effective December 31, 2003, that establish a joint...