Virus Weekly articles from February 2003

Virus Weekly archives from February 2003

Human cytomegalovirus genomes highly divergent.
February 4, 2003... 2003 FEB 4 - (NewsRx.com & NewsRx.net) -- According to a study from Italy, "The low-passage Toledo strain of human cytomegalovirus (HCMV) and fresh clinical HCMV isolates have been reported to share the capacity to propagate efficiently in...

Virus trashes detection mechanism to hide from immune system.
February 4, 2003... 2003 FEB 4 - (NewsRx.com & NewsRx.net) -- Herpes viruses are notorious for their ability to hide from the immune system and establish lifelong infections. Researchers at Washington University School of Medicine in St. Louis have discovered how...

Antiretroviral therapy heightens long-term hepatitis C virus diversity.
February 4, 2003... 2003 FEB 4 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - HIV treatment can exacerbate long-term hepatitis C virus (HCV) infection, researchers in California warn. Jennifer M. Babik and colleagues at Stanford...

Study finds three commonalities on timeline of hepatitis C pathogenesis.
February 4, 2003... 2003 FEB 4 - (NewsRx.com & NewsRx.net) -- Researchers in the United states have constructed a timeline demonstrating the early route of pathogenesis in people who become infected with hepatitis C virus. "To define the early events that...

HIV and herpesviruses DNA levels elevated in semen after vasectomy.
February 4, 2003... 2003 FEB 4 - (NewsRx.com & NewsRx.net) -- Semen from vasectomized animals infected with sexually transmissible viruses carries easily detectable levels of viral DNA, researchers in Switzerland say. "Ovine herpesvirus 2 (OvHV-2), a member...

Enhancing alpha-helicity HIV peptide increases affinity for human monoclonal antibody 2F5.
February 4, 2003... 2003 FEB 4 - (NewsRx.com & NewsRx.net) -- "The synthetic peptide DP178, derived from the carboxyl-terminal heptad repeat region of human immunodeficiency virus type 1 GP41 protein is a potent inhibitor of viral-mediated fusion and contains the...

Former WebMD executive producer joins NewsRx.
February 4, 2003... 2003 FEB 4 - (NewsRx.com & NewsRx.net) -- A former WebMD executive producer and medical editor has joined Atlanta-based NewsRx, along with three board-certified editors. Dominique Walton Brooks, MD, with WebMD until 2001, will serve as...

Real-time PCR assay enables human herpesvirus 8 DNA quantitation in biological fluids.
February 4, 2003... 2003 FEB 4 - (NewsRx.com & NewsRx.net) -- "Accurate laboratory tests for the diagnosis of active human herpesvirus 8 (HHV-8) infection are becoming essential to study the pathogenesis of HHV-8-associated tumors," such as Kaposi's sarcoma, "and...

Cyclin-dependent kinases may be therapeutic targets.
February 4, 2003... 2003 FEB 4 - (NewsRx.com & NewsRx.net) -- Researchers in Canada have identified a novel set of potential therapeutic targets in HIV and other viruses. "Cyclin-dependent kinases (cdks) are required for replication of viruses that replicate...

Strand transfer in retroviruses occurs through a pause-initiated two-step mechanism.
February 4, 2003... 2003 FEB 4 - (NewsRx.com & NewsRx.net) -- Researchers at the University of Rochester have elucidated the mechanisms underlying genetic recombination in retroviruses such as HIV. "Recombination promotes retrovirus evolution," explained R....

Antigens from swine or human virus both equally effective in assays.
February 4, 2003... 2003 FEB 4 - (NewsRx.com & NewsRx.net) -- Scientists who work for the United States government have completed a study suggesting the antigenic regions on swine and human hepatitis E viruses are nearly identical. "The recombinant truncated...

Glial cells play a role in defense against herpesvirus infections.
February 4, 2003... 2003 FEB 4 - (NewsRx.com & NewsRx.net) -- According to recent research from the United States, "Glial cells can respond to herpesvirus infections through the production of cytokines and chemokines. Although specific interactions between...

Human polyomavirus JCV linked to colon cancer.
February 4, 2003... 2003 FEB 4 - (NewsRx.com & NewsRx.net) -- Polyomavirus infections could promote colon cancer, researchers in the United States argue. "Infection of the gastrointestinal tract by the human polyomavirus, JCV, which has been frequently...

Nested PCR assay simultaneously detects several respiratory viruses.
February 4, 2003... 2003 FEB 4 - (NewsRx.com & NewsRx.net) -- A novel molecular assay can simultaneously detect a wide range of respiratory viruses, researchers in Spain say. "The clinical presentation of infections caused by the heterogeneous group of the...

Report addresses reduction of influenza burden in children.
February 4, 2003... 2003 FEB 4 - (NewsRx.com & NewsRx.net) -- "Epidemiologic studies indicate that children with certain chronic conditions, such as asthma, and otherwise healthy children younger than 24 months are hospitalized for influenza and its complications...

Long-term complications of CMV hepatitis after transplantation few.
February 4, 2003... 2003 FEB 4 - (NewsRx.com & NewsRx.net) -- Cytomegalovirus causes few long-term complications in patients who have undergone liver transplantations. According to recent research from Germany, "Cytomegalovirus (CMV) hepatitis is described as...

Apoptosis induced by infection with Gilchrist strain of rubella virus.
February 4, 2003... 2003 FEB 4 - (NewsRx.com & NewsRx.net) -- According to recent research from Argentina, "Apoptosis is an active process of cellular self-destruction, which can be initiated in response to several stimuli such as toxic substances, hormones,...

Novel promoter in human papillomavirus type 18 genome found.
February 4, 2003... 2003 FEB 4 - (NewsRx.com & NewsRx.net) -- "Northern blot and RT-PCR analyses indicated that the human papillomavirus E4 open reading frame is expressed in HeLa cells," researchers in the United States report. "Because integration at the E1...

Rotavirus particles survive tropical temperatures for more than 2 months.
February 4, 2003... 2003 FEB 4 - (NewsRx.com & NewsRx.net) -- "Typing and in vitro cultivation of rotavirus-positive human stool samples stored unintentionally at ambient tropical temperatures for 2 1/2 months showed that rotavirus is stable and may still be...

Review of non-A-E hepatitis cases eventually leads to hepatitis B.
February 4, 2003... 2003 FEB 4 - (NewsRx.com & NewsRx.net) -- Highly sensitive laboratory testing has identified hepatitis B virus or hepatitis C virus infection in several patients originally diagnosed with non-A-E hepatitis. "In an effort to determine the...

Respiratory syncytial virus enhances OVA response.
February 11, 2003... 2003 FEB 11 - (NewsRx.com & NewsRx.net) -- "In mice, respiratory syncytial virus (RSV) infection during allergic provocation aggravates the allergic Th2 immune response, characterized by production of interleukin (IL)-4, IL-5, and IL-13, and...

Cytomegalovirus tegument protein pp65 useful for specific immunity research.
February 11, 2003... 2003 FEB 11 - (NewsRx.com & NewsRx.net) -- Researches in Japan have identified a viral protein that may be useful in studies on cytomegalovirus (CMV)-specific immune activity. Such research is "important to better understand and manage CMV...

Interferon-gamma gene profiles may dictate recovery from hepatitis B virus.
February 11, 2003... 2003 FEB 11 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Among the alphabet soup of cytokines that regulate immune response, only genes for interferon (IFN)-gamma stand out as a link between hepatitis B virus (HBV)...

CDC issues recommendations for correctional settings.
February 11, 2003... 2003 FEB 11 - (NewsRx.com & NewsRx.net) -- The U.S. Centers for Disease Control and Prevention (CDC) has published recommendations designed to prevent and control viral hepatitis infections in correctional settings. Implementation of these...

Human papillomavirus oncoproteins E6 and E7 function to resist apoptosis.
February 11, 2003... 2003 FEB 11 - (NewsRx.com & NewsRx.net) -- "The oncogenic potential of high risk human papillomaviruses can be mainly attributed to two small proteins called E6 and E7. Even though these oncoproteins have a low molecular size, they are highly...

Antibody levels remain high in macaques given Quil A-adjuvanted measles vaccine.
February 11, 2003... 2003 FEB 11 - (NewsRx.com & NewsRx.net) -- According to a study from the Netherlands, "Quil A-based candidate measles vaccines have been shown to be immunogenic and protective in cotton rats and macaques. Here we studied the longevity of...

Research suggests genetic risk for virus-related malignancy in Indian women.
February 11, 2003... 2003 FEB 11 - (NewsRx.com & NewsRx.net) -- "The objective of the present study was to determine the codon 72 genotypic frequencies of p53 in Indian women and to analyze the association of this polymorphism with human papillomavirus (HPV)...

Detection of high-risk human papillomavirus a means of patient management.
February 11, 2003... 2003 FEB 11 - (NewsRx.com & NewsRx.net) -- High-risk human papillomavirus can be used for tracking women who may eventually develop high-grade cervical lesions. According to researchers in England, "this study was undertaken to investigate...

Subclinical Japanese encephalitis infection high in vaccinated populations.
February 11, 2003... 2003 FEB 11 - (NewsRx.com & NewsRx.net) -- According to recent research from Japan, "Japanese encephalitis (JE) virus is characterized as a virus that produces a large number of subclinical infections. In this report, we estimated a ratio of...

T cell dynamics explain differential CD4(+) depletion.
February 11, 2003... 2003 FEB 11 - (NewsRx.com & NewsRx.net) -- According to recent research from the United States, "deuterated glucose labeling was used to measure the in vivo turnover of T lymphocytes. A realistic T cell kinetic model, with populations of...

Adenoviral vector encoding for hepatitis C virus molecule prevents infection.
February 11, 2003... 2003 FEB 11 - (NewsRx.com & NewsRx.net) -- A recombinant vaccine comprised of the hepatitis C virus (HCV) NS3 protein and an adenoviral vector has induced immune response in animal models. According to a study from Spain, "cellular immune...

Prolonged HAART may cause higher hepatitis C load in HIV coinfected.
February 11, 2003... 2003 FEB 11 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Long-term use of highly active antiretroviral therapy (HAART) may be responsible for raising hepatitis C virus (HCV) loads in patients coinfected with human...

HHV-6 reactivation and disease exacerbation are found to be linked.
February 11, 2003... 2003 FEB 11 - (NewsRx.com & NewsRx.net) -- Recent research from Latvia "examined the association between HHV-6 infection and multiple sclerosis (MS) and the relationship between HHV-6 reactivation and disease activity. The frequency of HHV-6...

Immunopathogenesis of condition will enhance understanding.
February 11, 2003... 2003 FEB 11 - (NewsRx.com & NewsRx.net) -- A recent review from the United States, "focuses on current approaches to understanding the immunopathogenesis of human T cell lymphotropic virus (HTLV) type I associated myelopathy/tropical spastic...

More outbreaks seen in U.S., CDC reports.
February 11, 2003... 2003 FEB 11 - (NewsRx.com & NewsRx.net) -- Noroviruses, the category of viruses that caused thousands of cruise ship passengers to fall ill last year, appear to be on the rise in the United States, federal officials say. Further, the U.S....

Live attenuated measles-mumps-rubella-varicella vaccine found effective.
February 11, 2003... 2003 FEB 11 - (NewsRx.com & NewsRx.net) -- According to recent research from Australia, "In countries where routine varicella vaccination is implemented, it is usually given at the same age as that recommended for measles-mumps-rubella (MMR)...

Vaccine candidates in to prevent and treat STDs reviewed.
February 11, 2003... 2003 FEB 11 - (NewsRx.com & NewsRx.net) -- According to recent research from France, "Sexually transmitted diseases (STDs) are caused by organisms that infect the mucosal surfaces of the genitourinary tract. In spite of its public health...

Cytomegalovirus-infected cells express viral genes that may play role in latency.
February 11, 2003... 2003 FEB 11 - (NewsRx.com & NewsRx.net) -- "Human cytomegalovirus (HCMV) resides latently in hematopoietic cells of the bone marrow," according to recent research from the United States. "Although viral genomes can be found in CD14+ monocytes...

CpG oligodeoxynucleotides enhance immune response to herpesvirus vaccine.
February 11, 2003... 2003 FEB 11 - (NewsRx.com & NewsRx.net) -- According to a study from Canada, "Vaccine adjuvants must have the capacity to increase protective immune responses with minimal side effects. Conventional adjuvants not only cause undesirable tissue...

Sexual transmission often the source of hepatitis B and C infection in Russia.
February 11, 2003... 2003 FEB 11 - (NewsRx.com & NewsRx.net) -- Scientists in Russia blame sexual transmission as the primary route of infection for many new hepatitis B and C cases in Russia. According to a study from Russia, "it is generally understood that...

New variant of varicella-zoster virus identified.(Brief Article)
February 18, 2003... 2003 FEB 18 - (NewsRx.com & NewsRx.net) -- According to a study from Canada, "In 1998, a varicella-zoster virus glycoprotein E (gE) mutant virus (VZV-MSP) was isolated from a child with chickenpox. VZV-MSP, representing a second VZV serotype,...

Antibodies critical for fighting infection.
February 18, 2003... 2003 FEB 18 - (NewsRx.com & NewsRx.net) -- Researchers at Washington University School of Medicine in St. Louis have found that immune cells called B cells and the antibodies they produce play a critical early role in defending the body against...

Virus-specific cytotoxic T cells characterized.(HIV specific cells)
February 18, 2003... 2003 FEB 18 - (NewsRx.com & NewsRx.net) -- Researchers in Switzerland have provided new insight into the features of cytotoxic T cells specific to HIV and other viruses. K. Ellefsen and colleagues at the University of Lausanne...

Amino acid residues compatible with hepatitis B virus virion formation.
February 18, 2003... 2003 FEB 18 - (NewsRx.com & NewsRx.net) -- According to a study from Germany, "the crystal structure of recombinant hepatitis B virus (HBV) capsids formed by 240 core proteins has recently been published. We wanted to map sites on the surface...

How to efficiently triage HPV screen-positive at-risk patient.(human papillomavirus )(Brief Article)
February 18, 2003... 2003 FEB 18 - (NewsRx.com & NewsRx.net) -- "Current efforts to develop a vaccine against HPV are certainly promising. At this time little, if any, of the vast knowledge base being generated by current research is available for practical...

Norwalk virus-induced hemagglutination potentiated by gut antigens.
February 18, 2003... 2003 FEB 18 - (NewsRx.com & NewsRx.net) -- "Noroviruses are a major cause of epidemic acute nonbacterial gastroenteritis worldwide," according to a recent study from the United States. A. M. Hutson and colleagues at the Baylor College of...

Angiostatin inhibits extracellular HIV-Tat-induced inflammatory angiogenesis.
February 18, 2003... 2003 FEB 18 - (NewsRx.com & NewsRx.net) -- Researchers at Italy's National Institute for Cancer Research say angiostatin can ameliorate human immunodeficiency virus (HIV) protein-induced angiogenesis. "The HIV-Tat protein can be released...

Age differences are found for human papillomavirus type and prevalence.
February 18, 2003... 2003 FEB 18 - (NewsRx.com & NewsRx.net) -- "In a collection of 173 cervical adenocarcinomas, the prevalence of HPV in relation to the age of women and the distribution of the various oncogenic types of HPV were evaluated. The tumor material was...

JC virus may be biomarker for tumors.(colorectal cancer biomarker)(Brief Article)
February 18, 2003... 2003 FEB 18 - (NewsRx.com & NewsRx.net) -- "Chromosomal instability (CIN) is present in most colorectal cancers, though the mechanism for these genetic aberrations is unclear," researchers in the United States report. "An explanation may...

DC-SIGN gene family variations seen between human and nonhuman primates.
February 18, 2003... 2003 FEB 18 - (NewsRx.com & NewsRx.net) -- "Two CD209 family genes identified in humans, CD209 (DC-SIGN) and CD209L (DC-SIGNR/L-SIGN), encode C-type lectins that serve as adhesion receptors for ICAM-2 and ICAM-3 and participate in the...

N-linked glycan g15 in gp120 V3 loop blocks neutralizing antibodies.(HIV protein)
February 18, 2003... 2003 FEB 18 - (NewsRx.com & NewsRx.net) -- Researchers in Germany have shed new light on the role of some HIV protein components in preventing the effects of neutralizing antibodies. S. Polzer and colleagues at the Bernhard Nocht Institute...

Membrane-binding domain region involved in retroviral budding identified.(Brief Article)
February 18, 2003... 2003 FEB 18 - (NewsRx.com & NewsRx.net) -- "Budding of C-type retroviruses begins when the viral Gag polyprotein is directed to the plasma membrane by an N-terminal membrane-binding (M) domain," according to a recent study from Penn State...

HAART-persistent HIV-1 latent reservoirs may be eliminated by immune activation.(Brief Article)
February 18, 2003... 2003 FEB 18 - (NewsRx.com & NewsRx.net) -- According to recent research from the United States, "highly active antiretroviral therapy (HAART) has dramatically altered the human immunodeficiency virus type 1 (HIV-1) pandemic in the developed...

Indinavir/ritonavir provided viral suppression in PI-naive patients.
February 18, 2003... 2003 FEB 18 - (NewsRx.com & NewsRx.net) -- According to a study from the United States, "Low-dose ritonavir can boost plasma levels of indinavir, thereby enhancing its antiretroviral activity despite less frequent dosing. In this open-label,...

Asialoglycoprotein receptor plays role in hepatitis C virus infectivity.
February 18, 2003... 2003 FEB 18 - (NewsRx.com & NewsRx.net) -- Researchers in the United states say hepatitis C virus localizes with and is internalized by asialoglycoprotein receptors on liver cells. "We used a baculovirus-based system to prepare structural...

Hepatitis C virus E1 protein hydrophobic area important for protein interactions.(Brief Article)
February 18, 2003... 2003 FEB 18 - (NewsRx.com & NewsRx.net) -- According to recent research from Taiwan, "The interaction between the hepatitis C virus capsid protein and the envelope protein E1 has been demonstrated previously in vivo. To determine the binding...

Acute hepatitis caused by hepatitis E infection acquired in the Netherlands.(Brief Article)
February 18, 2003... 2003 FEB 18 - (NewsRx.com & NewsRx.net) -- "Increasing evidence suggests that hepatitis E virus (HEV) infection may occur in developed countries and that swine may act as a reservoir. We report a cluster of two confirmed cases and one...

Cidofovir fails to treat Kaposi sarcoma in a pilot study.(Brief Article)
February 18, 2003... 2003 FEB 18 - (NewsRx.com & NewsRx.net) -- According to a study from the United States, "a clinical trial was conducted to test the activity of cidofovir (CDV), a drug with in vitro activity against Kaposi sarcoma (KS) associated herpesvirus...

Periodontal CMV linked to subgingival D. pneumosintes and alveolar bone loss.
February 18, 2003... 2003 FEB 18 - (NewsRx.com & NewsRx.net) -- "Destructive periodontal disease is associated with human cytomegalovirus (HCMV), Epstein-Barr type 1 virus (EBV-1) and other members of the Herpesviridae family as well as with various Gram-negative...

Venezuelan equine encephalitis virus structure characterized.
February 18, 2003... 2003 FEB 18 - (NewsRx.com & NewsRx.net) -- "Venezuelan equine encephalitis virus (VEEV) is an important human and equine pathogen in the Americas, with widespread reoccurring epidemics extending from South America to the southern United...

Influenza virus matrix protein plus ribonucleoproteins may control viral growth.
February 18, 2003... 2003 FEB 18 - (NewsRx.com & NewsRx.net) -- According to a study from the United States, "The matrix protein (M1) of influenza virus plays a central role in viral replication. In relation to viral growth and morphology, we studied the...

Genetic analysis of Rift Valley fever viruses reported.
February 18, 2003... 2003 FEB 18 - (NewsRx.com & NewsRx.net) -- According to recent research from the United States and Saudi Arabia, "The first confirmed Rift Valley fever outbreak outside Africa was reported in September 2000, in the Arabian Peninsula. As of...

Rift Valley Fever virus from Aedes vexans arabiensis found in Saudi Arabia.(Brief Article)
February 18, 2003... 2003 FEB 18 - (NewsRx.com & NewsRx.net) -- According to recent research from the United States, " An outbreak of Rift Valley fever in the Kingdom of Saudi Arabia and Yemen in 2000 was the first recognized occurrence of the illness outside of...

Baculoviruses capable of targeting select brain centers for gene delivery.
February 18, 2003... 2003 FEB 18 - (NewsRx.com & NewsRx.net) -- Researchers announced baculoviruses are able to deliver gene therapies to designated sectors within the brain with a high degree of selectivity. "Baculoviruses have recently been shown to be...

Modified herpes simplex virus delivers genes to central nervous system.(Brief Article)
February 18, 2003... 2003 FEB 18 - (NewsRx.com & NewsRx.net) -- Modifications to the herpes simplex virus allows it to deliver genes to various areas of the central nervous system, researchers in the U.S. report. "Controlled expression of proteins is a key...

Research compares DNA and RNA extraction methods for mummified tissues.
February 18, 2003... 2003 FEB 18 - (NewsRx.com & NewsRx.net) -- According to a study from the United States, "nucleic acids extracted from mummified tissues are valuable materials for the study of ancient human beings. Significant difficulty in extracting nucleic...

Viral pathogens, virus-induced IL-8 correlate with symptom generation.
February 18, 2003... 2003 FEB 18 - (NewsRx.com & NewsRx.net) -- "Both virus-mediated damage to airway tissues and induction of pro-inflammatory cytokines such as interleukin-8 (IL-8) could contribute to symptom severity during viral respiratory infections in...

Rituximab clears complications arising from Epstein-Barr virus hepatitis.(Brief Article)
February 18, 2003... 2003 FEB 18 - (NewsRx.com & NewsRx.net) -- According to recent research from Belgium, "Post-transplantation lymphoproliferative disorders (PTLDs) are life-threatening complications. We report the case of a 7-year-old girl in whom a...

Macrophages and dendritic cells can rapidly cross-present Ag from live cells.(Brief Article)
February 18, 2003... 2003 FEB 18 - (NewsRx.com & NewsRx.net) -- According to a study from the United States, "professional APCs (pAPC) can process and present on their own MHC class I molecules' antigens (Ags) acquired from Ag donor cells (ADC). This phenomenon of...

Mutant herpes simplex virus type 1 thymidine kinase a gene expression marker.
February 18, 2003... 2003 FEB 18 - (NewsRx.com & NewsRx.net) -- A mutated herpes simplex virus type thymidine kinase enzyme may be better than its wild-type counterpart for monitoring gene delivery. "Current gene therapy protocols often suffer from an inability...

Blockade of receptor expression or virus interactions offers therapeutic options.
February 18, 2003... 2003 FEB 18 - (NewsRx.com & NewsRx.net) -- According to a study from Germany, "The molecular determinants of cardiac viral infections are currently under intense investigation because an understanding of these determinants may lead to an...

Researchers present new information on the common cold.(Brief Article)
February 18, 2003... 2003 FEB 18 - (NewsRx.com & NewsRx.net) -- According to recent research from Finland, "Despite great advances in medicine, the common cold continues to be a great burden on society in terms of human suffering and economic losses. Of the...

Latency-related gene of bovine herpesvirus-1 disables productive infection.(Brief Article)
February 18, 2003... 2003 FEB 18 - (NewsRx.com & NewsRx.net) -- According to recent research from the United States, "transfection of bovine cells with bovine herpesvirus-1 genomic DNA yields low levels of infectious virus. Cotransfection with the bICPO gene...

Selectins and integrins play role in adenovirus vector-induced recruitment.
February 18, 2003... 2003 FEB 18 - (NewsRx.com & NewsRx.net) -- According to a study from Canada, "adenovirus vectors for human gene therapy induce early host inflammatory responses in transduced tissues that limit gene transfer efficiency and can result in...

Technique quantifies quasi-equivalence in icosahedral viruses.
February 18, 2003... 2003 FEB 18 - (NewsRx.com & NewsRx.net) -- Researchers have developed a method for quantifying quasi-equivalence in certain viruses, according to a report from the United States. "A quantitative, atom-based, method is described for...

SV40 lytic infection triggers components of a DNA damage checkpoint pathway.
February 25, 2003... 2003 FEB 25 - (NewsRx.com & NewsRx.net) -- According to a study from the United States, "Lytic infection of African green monkey kidney (CV-1) cells by simian virus 40 (SV40) is characterized by stimulation of DNA synthesis leading to bypass of...

Combination of methods offers reasons for why hepadnaviruses are persistent.
February 25, 2003... 2003 FEB 25 - (NewsRx.com & NewsRx.net) -- "The detection of small amounts of viral pathogens in infected cells by classical PCR is hampered by a partial loss of virus nucleic acid due to extraction and by difficulties in discrimination between...

Frequent genetic reassortment seen among influenza C viruses.
February 25, 2003... 2003 FEB 25 - (NewsRx.com & NewsRx.net) -- Researchers in Japan have shed new light on the genetic makeup of influenza C viruses. "In a nine-year survey from December 1990 to December 1999 in Sendai City, Japan, we succeeded in isolating a...

Multimerization of hantavirus nucleocapsid protein depends on type-specific epitopes.
February 25, 2003... 2003 FEB 25 - (NewsRx.com & NewsRx.net) -- Researchers in Japan have elucidated the multimerization process of a key hantavirus protein. "Multimerization of the Hantaan virus nucleocapsid protein (NP) in Hantaan virus-infected Vero E6 cells...

Influenza vaccination safe and effective in individuals infected with HIV.
February 25, 2003... 2003 FEB 25 - (NewsRx.com & NewsRx.net) -- According to a study from Italy, "Influenza can cause severe complications in HIV-infected individuals leading to increases in hospitalization and mortality. Vaccination is recommended for such...

Understanding CD150 receptor viruses may lead to better antiviral vaccines.
February 25, 2003... 2003 FEB 25 - (NewsRx.com & NewsRx.net) -- According to recent research from the Ukraine and the United States, "The CD150 subfamily within the CD2 family is a growing group of dual-function receptors that have within their cytoplasmic tails a...

New packaging cell line for SV40 vectors mitigates T-antigen recombinants.(Brief Article)
February 25, 2003... 2003 FEB 25 - (NewsRx.com & NewsRx.net) -- "Simian virus 40 (SV40) vectors are efficient vehicles for gene delivery to hematopoietic and hepatic cells. To ensure their replication incompetence and because of safety considerations, it is...

Adjuvanted multicomponent protein vaccine prevents AIDS in rhesus monkeys.
February 25, 2003... 2003 FEB 25 - (NewsRx.com & NewsRx.net) -- According to recent research from Belgium and the United States, "Recombinant protein subunit AIDS vaccines have been based predominantly on the virus envelope protein. Such vaccines elicit...

Viral evolution and challenges in the development of HIV vaccines outlined.(Brief Article)
February 25, 2003... 2003 FEB 25 - (NewsRx.com & NewsRx.net) -- According to a study from the United States, "Potent virus-specific cytotoxic T lymphocyte (CTL) responses elicited by candidate AIDS vaccines have been shown to provide short-term control of viral...