Virus Weekly articles from December 2004

Virus Weekly archives from December 2004

CMV UL84 insertion mutant is defective for viral DNA synthesis and growth.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- The human cytomegalovirus UL84 insertion mutant is defective for viral DNA synthesis and growth. According to a study from the United States, "Human cytomegalovirus (HCMV) UL84 is required for...

HIV-infected patients with CNS HSV coinfection have varied presentations.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- HIV-infected patients with a CNS HSV coinfection have varied presentations. According to recent research published in the International Journal of STD & AIDS, "We report clinical, radiological and...

Novel SNP in human perforin gene associated with outcome of HTLV-1 infection.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- A novel SNP in the human perforin gene is associated with the outcome of HTLV-1 infection. According to recent research published in the journal Human Immunology, "Human T lymphotropic virus I...

Lentivirus clone SIVmac239 does not complete capsid assembly in cell-free system.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- A lentivirus clone, SIVmac239, does not complete capsid assembly in a cell-free system. According to published research from the United States, "We have previously described a cell-free system that...

Novel SARS-CoV entry inhibitor may be a viable candidate therapy for SARS.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- A novel SARS coronavirus entry inhibitor may be a viable candidate therapy for SARS. "Infection of receptor-bearing cells by coronaviruses is mediated by their spike (S) proteins. The coronavirus...

HIV linked to depletion of CD4+ T cells from effector sites in GI tract.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites in the gastrointestinal tract. According to a study from the United States and Germany,...

Nuclear localization of adenovirus E4orf4 protein correlates with cell death.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Nuclear localization of adenovirus E4orf4 protein correlates with cell death. "The adenovirus E4orf4 protein induces p53-independent death of human cancer cells by a mechanism requiring interactions...

Domestic ducks could pose new avian influenza threat.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Domestic ducks may be acting as a silent reservoir for the H5N1 Avian Influenza virus, which is highly pathogenic for chickens, and may thus have acquired an important new role in the transmission of...

Glycerol plus polyvinylpyrrolidone optimally preserves frozen bone marrow cells.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Glycerol plus polyvinylpyrrolidone optimally preserves frozen bone marrow cells. According to a study from the Netherlands, "Quantitative studies are presented of the effect of different storage...

Molecular diagnostics company announces expansion of diagnostic pipeline.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Third Wave Technologies Inc. (TWTI) provided new details about the expansion of the company's molecular diagnostic pipeline and issued preliminary guidance for 2005 clinical molecular diagnostic...

Hepatitis C infection encourages liver cancer recurrence after resection.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Hepatitis C infection encourages liver cancer recurrence after resection. "Hepatocellular carcinoma (HCC) is closely associated with chronic hepatitis B or C virus (HBV, HCV) infection. Tumor...

HPV 16 infection a risk factor for disease progression in younger women.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Infection with human papillomavirus 16 infection is a significant risk factor for cervical cancer progression in younger women, study data indicate. "Human papillomaviruses (HPV), particularly type...

Small cell neuroendocrine carcinomas of the uterine cervix characterized.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Pathologists with Yamagata University, Japan, recently characterized small cell neuroendocrine carcinomas of the uterine cervix. G.M. Ishida and colleagues stated, "Small cell carcinomas of the...

Companies introduce solid support product for manufacture of oligonucleotides.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Nitto Denko Corporation, a polymer company, and Isis Pharmaceuticals, Inc. (ISIS), a RNA-based drug discovery and development company, have jointly developed a new solid support for the manufacture of...

Cryptococcus neoformans outbreak at Vancouver Hospital between 1997-2002.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- A Cryptococcus neoformans outbreak at Vancouver Hospital between 1997-2002 was note retrospectively. According to a study from Canada, "An outbreak of infections due to a rare subspecies of...

Cytomegalovirus inhibits cytokine-induced macrophage differentiation.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Cytomegalovirus inhibits cytokine-induced macrophage differentiation. According to a study from Sweden, "Human cytomegalovirus (HCMV) infection in immunocompromised patients is associated with...

Dengue viral infections reviewed.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Researchers review dengue viral infections in a recent issue of the Postgraduate Medical Journal. According to published research from Sri Lanka and England, "Dengue viral infections are one of the...

Computed tomography can identify HSV-related hepatitis in pregnant women.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Computed tomography can identify HSV-related hepatitis in pregnant women. According to published research from the United States, "fulminant hepatitis due to herpes simplex virus (HSV) is rare in...

Diagnostics products company announces reagent for common respiratory viruses.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Nanogen, Inc., (NASDAQ:NGEN) announced that it is developing new analyte specific reagents (ASRs) for clinical reference laboratories to develop and validate a single test to detect six of the most...

Novel chemiluminescent immunosensor assay detects serum CA19-9 levels.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- A novel chemiluminescent immunosensor assay detects serum CA19-9 levels. "A novel chemiluminescent immunosensor for carbohydrate antigen 19-9 (CA19-9) based on the immobilization of CA19-9 on the...

Universal microarray detects the severe acute respiratory syndrome coronavirus.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Universal microarray detects the severe acute respiratory syndrome coronavirus. "Severe acute respiratory syndrome (SARS) is caused by the SARS coronavirus (SARS-CoV). There are many point mutations...

African leaders, health activists push for money to fight disease.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Four African presidents appealed November 17, 2004, for new grants from a fund set up to combat three of the world's deadliest diseases, while the United States has called for restraint in spending...

Case of vertically transmitted HSV-2 infection resembled calcified myocarditis.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Obstetrician/gynecologists in Charlotte, North Carolina, have reported a case of congenital herpes simplex virus infection that appeared sonographically to be calcified myocarditis. "Congenital...

Disulfide bonds of Ebola-virus-secreted glycoprotein SGP assigned.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Scientists have assigned the disulfide bonds of the Ebola-virus-secreted glycoprotein SGP. "The non-structural glycoprotein (SGP) of Ebola virus (EboV) is secreted in large amounts from infected...

Biotechnology company reports improved third quarter results.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Lipid Sciences, Inc., reported financial results for the quarter ended Sept. 30, 2004. For the third quarter of 2004, Lipid reported a net loss of $3.2 million, or $.13 per share, on a basic and...

Diagnostics company reports 34% increase in Q1 revenues.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Digene Corp. (DIGE) reported financial results for the fiscal 2005 first quarter ended September 30, 2004. Total revenues for the quarter increased 34% to $26.2 million from $19.6 million in the...

Sindbis viral vectors detect and suppress advanced ovarian cancer xenografts.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Sindbis viral vectors detect and suppress advanced ovarian cancer xenografts. "We studied the therapeutic value of Sindbis vectors for advanced metastatic ovarian cancer by using two highly...

Company to begin shipping HIV-1 incidence test.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Calypte Biomedical Corporation (HIV) announced that it began shipping its HIV-1 BED Incidence EIA test (Incidence Test). The first shipment is destined for South Africa, and the company currently...

Interim results reported from tipranavir RESIST-1 phase III study.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- New data from a pivotal phase III study (RESIST-1) demonstrate that a statistically significant greater percentage of HIV-positive patients taking a tipranavir-based regimen achieved a treatment...

Monoclonal antibody among HIV therapies discussed at human virology meeting.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Tanox, Inc. (TNOX) medical director Stanley Lewis recently presented findings from the phase 1 clinical trial of TNX-355 for the treatment of human immunodeficiency virus (HIV) at the 2004 International...

Family home AIDS care in rural sub-Saharan Africa is a minimal burden.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Family home AIDS care in rural sub-Saharan Africa is a minimal burden. According to recent research from the United States, "In rural sub-Saharan Africa, most care for patients with AIDS is provided...

HAART adherence shifts during HIV infection course for women caring for children.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- HAART adherence shifts during the course of HIV infection for women caring for children. "Few studies have directly focused on adherence to highly active antiretroviral medication (HAART) in HIV...

HIV drug resistance not a problem if immune response maintains above threshold.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- HIV drug resistance is not a problem if immune response is maintained above threshold. "The treatment of viral infections using antiviral drugs has had a significant public health benefit in the...

Most recent common ancestor of HIV subtype C appeared in mid to late 1960s.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- The most recent common ancestor of HIV subtype C appeared in the mid- to late 1960s. "Human immunodeficiency virus type 1 (HIV-1) subtype C is responsible for more than 55% of HIV-1 infections...

Reduction in new HIV infections in Southeast Spain.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- There is a reduction in new HIV infections in Southeast Spain. "We analyze the characteristics of patients diagnosed with HIV infection in the highly active antiretroviral therapy era in the...

HIV-1 DNA burden stable in monocytes and CD4 cells after ART resumption.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- HIV-1 DNA burden is stable in monocytes and CD4 cells after the resumption of antiretroviral therapy. "Replication-competent HIV, as well as HIV-1 DNA, has been detected in CD4 T cells and in...

Russian government lacks will to combat spread of HIV/AIDS, experts say.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- AIDS and the HIV virus are spreading at an alarming pace in Russia, but the government lacks the political will to combat the epidemic that may claim tens of thousands of lives within the next few...

Complement mediates HIV binding to erythrocytes.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Complement mediates HIV binding to erythrocytes. According to a study from Switzerland, "A fraction of HIV is associated with erythrocytes even when the virus becomes undetectable in plasma under...

Distinct mechanisms of HIV-1 Nef action in different populations of target cells.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- There are distinct mechanisms of HIV-1 Nef action in different populations of target cells. According to a study from Canada, "HIV-1 Nef is a critical determinant of pathogenicity in humans and...

Entry/transcription key determinants of CD4 T-cell permissiveness to HIV-1.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Entry and transcription are the key determinants of CD4 T-cell permissiveness to HIV-1 infection. According to recent research from Switzerland, "Isolated primary human cells from different donors...

Fluorescent-labeled HIV-1 developed to investigate interaction with live cells.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- A fluorescent-labeled HIV-1 was developed in order to investigate its interaction with live cells. According to recent research published in the Journal of Virology, "The introduction of a label...

Novel method targeting HIV-1-Ag-SCs identifies latently HIV-1-infected CD4 cells.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- A novel method targeting HIV-1-antigen-secreting cells identifies latently HIV-1-infected CD4 cells. "In resting CD4+ T lymphocytes harboring human immunodeficiency virus type 1 (HIV-1),...

Prostratin antagonizes HIV latency by NF-kappa B activation.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Prostratin antagonizes HIV latency by NF-kappa B activation. According to recent research from the United States, "A subset of quiescent memory CD4 T cells harboring integrated but...

Prostratin inhibits infection/reactivates latent HIV in PBLs/lymphoid tissue.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Prostratin inhibits infection and reactivates latent HIV in peripheral blood lymphocytes and lymphoid tissue. "To design strategies to purge latent reservoirs of human immunodeficiency virus type 1...

Raft-promotion of virion-associated cholesterol determines HIV-1 infectivity.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Raft-promotion of virion-associated cholesterol determines HIV-1 infectivity. According to a study from Australia, "Lipid rafts are enriched in cholesterol and sphingomyelin and are isolated on the...

Riboswitch regulates RNA dimerization and packaging in HIV-1 virions.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- A riboswitch regulates RNA dimerization and packaging in HIV-1 virions. According to investigators in the Netherlands, "The genome of retroviruses, including human immunodeficiency virus type I...

Vpr nuclear localization crucial for efficient HIV-1 replication in CD4 cells.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Vpr nuclear localization is crucial for efficient HIV-1 replication in CD4 cells. According to recent research published in the journal Virology, "The human immunodeficiency virus type 1 (HIV-1)...

Measuring validity of self-reported symptoms among people with HIV.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- According to recent research from the United States, "Symptoms are important indicators of health and treatment for people with HIV. Symptoms are measured by patient self-report, but there has been...

Antiretroviral use differs by sociodemographic differences.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- The use of antiretroviral drugs vary by sociodemographic differences. According to published research from Canada, "The objective of this study was to examine the level of antiretroviral use and...

Clinical study results build case for expanded use of FUZEON.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Earlier use of FUZEON (enfuvirtide) in treatment-experienced HIV patients results in better treatment outcomes and preserves future drug options, according to new data presented at the 44th Interscience...

Data involving Combivir presented at recent meeting.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- A significant number of abstracts that include Combivir (lamivudine 150 mg and zidovudine 300 mg) Tablets were presented at the 44th Interscience Conference on Antimicrobial Agents and Chemotherapy in...

HIV CCR5 antagonist GW-873140 shows potent activity against primary isolates.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- The HIV CCR5 antagonist GW-873140 shows potent activity against primary isolates. According to a study from Spain, "The human immunodeficiency virus (HIV) is a highly mutative virus, representing a...

Novel HIV-1 mutation associated with resistance to nevirapine.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- A novel HIV-1 mutation is associated with resistance to nevirapine. "Several reports have recently shown that drug-resistant human immunodeficiency virus type 1 (HIV-1) is often isolated from...

Racivir phase II HIV study initiated.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Pharmasset, Inc., has initiated a phase II clinical study to assess the safety, tolerability, and antiviral effect of substituting Racivir (RCV) for Epivir (lamivudine, 3TC) in treatment-experienced...

Discreet species of gp41 high-MW aggregates present in HIV-related dementia.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Discreet species of gp41 high-molecular weight aggregates are present in HIV-related dementia. According to investigators in the United States, "Accumulation of the HIV envelope protein gp41 is...

Virus-mediated gene transfer is a candidate for treating hearing loss.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Virus-mediated gene transfer is a candidate for treating hearing loss. "Noise, chemicals and genetic defects are all common causes of irreversible hearing loss, which at present have no cure. Gene...

Signal peptide of arenavirus glycoprotein forms mature G1-G2 complex subunit.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- The signal peptide of the Junin arenavirus envelope glycoprotein is myristoylated and forms an essential subunit of the mature G1-G2 complex. "Arenaviruses comprise a diverse family of rodent-borne...

Positive results reported from phase I/II trial of ANA380 (LB80380).
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Anadys Pharmaceuticals, Inc., (ANDS) and LG Life Sciences, Ltd., (KOSPI: 68870) reported results from a recently completed phase I/II clinical trial of ANA380 (LB80380), an orally available compound for...

Payment received from GlaxoSmithKline relating to HEV vaccine.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Genelabs Technologies, Inc., (GNLB) has received a $750,000 payment from GlaxoSmithKline biologicals (GSK) based on a milestone relating to clinical trial results for GSK's investigational vaccine...

Pharmaceuticals advances to phase 1b trial for drug treatment of hepatitis C.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Vertex Pharmaceuticals Incorporated (VRTX) announced the initiation of a phase 1b clinical trial for VX-950, an investigational oral protease inhibitor for the treatment of hepatitis C virus (HCV)...

Early expression of HSV-1 ICP27 transcript not critical for replication.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Immediate-early expression of the herpes simplex virus type 1 ICP27 transcript is not critical for efficient replication in vitro or in vivo. "We constructed a promoter mutation altering the...

Factors associated with HPV-16 seropersistence in Costa Rican women identified.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Epidemiologists in the United States identified factors associated with seroconversion and seropersistence of human papillomavirus 16 (HPV-16) in a large group of women in Costa Rica. "Serologic...

Inflammatory responses in cervical neoplasia suppressed in HIV-positive women.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Inflammatory responses in cervical intraepithelial neoplasia are suppressed in HIV-positive women. "The role of mucosal immunity in human papillomavirus (HPV)-related cervical diseases is poorly...

Methods of identifying new antigenic epitopes of HPV 16 developed.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Scientists have developed new methods of identifying new antigenic epitopes of human papillomavirus type 16 E6 and E7 proteins. "Human papillomavirus (HPV) infection is the most common cause of...

Prevalence of HPV infection differs for men and women.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- The age-specific prevalence of sexually transmitted human papillomavirus infection in women differs substantially from that in men who have sex with men, according to a new study. The study was led...

Dendritic cell-based vaccines effective against HPV-associated tumors.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Dendritic cell-based vaccines were effective against HPV-associated tumors after surgical reduction. According to recent research from the Czech Republic, "Dendritic cell (DC)-based vaccines are...

Drug selection has little impact on hepatitis C severity after liver grafts.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Drug selection has little impact on hepatitis C severity after liver grafts. According to a study from the United States, "hepatitis C virus (HCV)-induced cirrhosis is the commonest indication for...

Gene-modified macrophages recognize apoptotic cells.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Gene-modified macrophages recognize apoptotic cells. According to recent research published in the journal FEBS Letters, "the resolution of inflammation is dependent on recognition and phagocytic...

Neugene antisense drugs reported to suppress influenza A virus.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- AVI BioPharma, Inc., (AVII) announced that Qing Ge, PhD, of the Massachusetts Institute of Technology (MIT) Center for Cancer Research, presented data characterizing the effect of AVI's Neugene drugs...

Take steps to minimize risk if getting the flu even without shot, expert says.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Millions of Americans who must forego a flu shot this year because of a vaccine shortage are feeling nervous, vulnerable, and wondering how they can best avoid the the illness. Some simple steps...

Flu season starts in Oregon.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- A 28-year-old man has Oregon's first confirmed case of the flu this season. The case was reported by Providence Portland Medical Center, Oregon health officials said. The flu typically kills...

Alabama nursing homes still waiting for flu shots.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Alabama nursing home residents are still waiting to get their flu shots after a second wave of vaccine was administered November 17, 2004, in county health departments. Over 100,000 doses of flu...

Chiron asks British regulators to inspect flu vaccine facility.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Chiron Corp. has asked British regulators to inspect its facility producing an experimental bird flu vaccine to make sure it doesn't run into the same contamination problems that forced the closing of...

HHS head Thompson announces contract to support egg supply for flu vaccines.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- The U.S. Department of Health and Human Services (HHS) Secretary Tommy G. Thompson announced that a contract was awarded to Sanofi Aventis Inc., part of the Sanofi Aventis Group, to ensure there are...

Hawaii opens flu shot clinics for chronically ill.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- The Hawaii Department of Health on November 15, 2004, held the first of many flu vaccine clinics for people who are chronically ill. Health officials expect to deliver about 10,000 flu shots to...

Ineffective vaccine given to about 300 in Arkansas, health official says.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- The state's top health official says some central Arkansas residents think they're protected from the flu, when they're not. Fay Boozman, MD, director of the state Health Department, said about 300...

Senator says money for new flu vaccine research probably on the.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- A senator suggested November 16, 2004, that money federal health officials were seeking to upgrade flu vaccine production is on the way, in an effort to avoid another year like this one, when the United...

Utah lifting flu shot restrictions.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Additional shipments of vaccine are allowing the Utah Department of Health to lift all restrictions for receiving the flu vaccine, the department announced November 17, 2004. Now, anyone over the...

Vermont to hold 17 flu shot clinics.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Statewide in Vermont, 17 clinics will administer 12,000 flu vaccines to people at highest risk from the flu. Vermont Health Commissioner Paul Jarris, MD, isn't sure what kind of turnout to expect...

Herpesvirus saimiri ORF73 modulates tumor suppressor proteins p53 and pRb.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Herpesvirus saimiri ORF73 modulates the tumor suppressor proteins p53 and pRb. "All known DNA tumor viruses are known to target and inactivate two main cell cycle regulatory proteins, retinoblastoma...

KSHV LANA up-regulates hTERT promoter transcription through Sp1 interaction.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- KSHV latency-associated nuclear antigen up-regulates human telomerase reverse transcriptase promoter transcription through interaction with Sp1. "Telomerase is required for the maintenance of...

Anti-MHC-class-II antibody delays rejection, but triggers CMV activation.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- A novel anti-MHC-class-II antibody delays rejection but triggers CMV activation in a primate model of kidney transplantation. "Treatment of kidney graft recipients with antibodies that may...

Cell-free systems compare capsid assembly of genetically diverse lentiviruses.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Cell-free systems were developed to compare capsid assembly of genetically diverse lentiviruses. "We recently demonstrated that capsids from three main primate lentiviral lineages appear to form...

Self-inactivating lentiviral vectors resist proviral methylation.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Self-inactivating lentiviral vectors resist proviral methylation. "Oncoretroviral expression is transcriptionally silenced in embryonic and hematopoietic stem cells (HSCs). This is associated with...