Virus Weekly articles from April 2004

Virus Weekly archives from April 2004

Herpesvirus ICP0 RING finger domain inhibits interferon-stimulated genes.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- The herpes simplex virus ICP0 RING finger domain inhibits IRF3 and IRF7-mediated activation of interferon-stimulated genes. According to recent research published in the Journal of Virology, "Virus...

Adaptive regulatory T cells suppress killing of persistently infected cells.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Scientists report that they have identified a cellular mechanism that prevents the immune system from destroying chronic, incurable viral infections such as herpes, hepatitis and human immunodeficiency...

"Male-targeting" bacterium's genome is deciphered.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Living inside the gonad cells of more than a million species of insects, spiders, crustaceans and worms, most members of the Wolbachia family of intracellular bacteria manipulate the reproduction of...

Influenza A viruses obtained from Vero cells by reverse genetics.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- High-yielding influenza A viruses obtained from African green monkey kidney (Vero) cells by reverse genetics. "Influenza A viruses are the cause of annual epidemics of human disease with occasional...

Combination of medication, light therapy increases presence of HPV in skin.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Patients with psoriasis who have been treated with a combination of drug (psoralen) and ultraviolet light therapy have an increased prevalence of human papillomavirus (HPV) in their skin, according to...

Chimpanzees permit hepatic quantification of hepatitis B virus cccDNa.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Chimpanzees permit hepatic quantification of hepatitis B virus cccDNa. "We have previously shown that hepatitis B virus (HBV) replication is controlled by noncytolytic mechanisms that depend...

CDC removes Hong Kong from bird ban.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- The U.S. Centers for Disease Control and Prevention (CDC) has removed Hong Kong from the jurisdictions included in an importation ban on birds and bird products. The decision to remove Hong Kong is...

Chinese delegation visits Delaware to discuss avian influenza.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Delaware officials met March 16, 2004, with a delegation from the Chinese embassy to explain what the state has done to control an avian flu outbreak and request that China lift an import ban on...

Lamivudine helps keep HBV at bay during cancer chemotherapy.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Researchers in Hong Kong have discovered a way to help prevent the reactivation of the hepatitis B virus (HBV) in women who are being treated with chemotherapy for breast cancer. Winnie Yeo, an...

The ribavirin prodrug viramidine has proven safe in healthy volunteers.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- The ribavirin prodrug viramidine has proven safe in healthy volunteers. "Ribavirin, part of the current first-line combination therapy for the treatment of chronic hepatitis C, has side effects - in...

Non-radioactive labeled hepatitis B virus probes are sensitive and inexpensive.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Non-radioactive labeled hepatitis B virus probes are sensitive and inexpensive. "A method using non-radioactive material alkaline phosphatase to label HBV DNA as probe has been studied and used in...

Betulonic acid-based agents active against HIV, influenza A, other viruses.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- A group of betulonic acid-based agents have demonstrated activity against a variety of viruses, including HIV. In a study from Russia, "[b]etulonic acid amides with aliphatic and heterocyclic...

Cell-penetrating, Rev-binding peptides can protect against HIV.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- A novel class of cell-penetrating, Rev-binding peptides may protect against HIV infection. "New therapeutic agents able to block HIV-1 replication are eagerly sought after to increase the...

Fungal derivatives show promise as HIV integrase inhibitors.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- A series of fungal derivatives are highly active against a key HIV enzyme. "HIV-1 integrase is a critical enzyme for replication of HIV, and its inhibition is one of the most promising new drug...

Novel benzophenones show promise as anti-HIV NNRTIs.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Novel benzophenone non-nucleoside reverse transcriptase inhibitors (NNRTIs) are highly active against drug-resistant strains of HIV. In a recent study from Japan, the agents "GW4511, GW4751, and...

Avidin-displaying baculovirus enhances gene delivery.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Avidin-displaying baculovirus enhances gene delivery. "Flexible alteration of virus surface properties would be beneficial for enhanced and targeted gene delivery. A useful approach could be based...

New avidin-biotin complexes may carry oligo-DNA to the liver.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- New avidin-biotin complexes may carry oligo-DNA to the liver. "To establish an effective nonviral gene transfer vector to hepatocytes, various oligo-carrier complexes were developed employing...

Vestigial theta-defensin pseudogenes identified in humans.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- A group of vestigial theta-defensin pseudogenes have been identified in the human genome. According to recent research from the United States, "[r]etrocyclins (ancestral human theta-defensins) are...

Chemotherapy and HAART feasible for HIV-NHL patients.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Simultaneous chemotherapy and HAART regimens are feasible for HIV patients with non-Hodgkin lymphoma. Researchers in Italy "evaluated replication of human immunodeficiency virus (HIV) and the...

Soluble Fas levels in CSF correlate with HIV dementia severity.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Cerebrospinal fluid (CSF) sFas levels are correlated with the severity of HIV-associated dementia (HIV-D). "Soluble Fas (sFas) and soluble Fas ligand (sFasL) are associated with cellular...

MQoL-HIV provides accurate quality-of-life measure for Japanese HIV patients.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- The MQoL-HIV test is suitable for measuring quality of life in Japanese HIV patients. Scientists in Japan conducted a study "to evaluate the discriminative properties of the Multidimensional Quality...

Changes in patterns of HIV infection in Italy characterized.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Changes in the epidemiology of HIV infection in Italy have been characterized. In a recent study, a group of researchers sought to characterize "the major changes in the human immunodeficiency...

First Mycobacterium haemophilum infection in AIDS patient in Italy reported.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- The first Mycobacterium haemophilum infection in an AIDS patient in Italy has been reported. M. haemophilum, "a strongly acid- and alcohol-fast bacillus belonging to the group of nontuberculous...

Novel Cryptococcus species isolated from AIDS patients.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- A novel Cryptococcus species has been identified. In a recent study from Japan, C. flavescens, "a strain originally identified as C. laurentii, was isolated from the cerebrospinal fluid of an AIDS...

Membrane-active gp41 regions identified.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Membrane-active regions of HIV gp41 have been identified using a novel technique. According to published research from Spain, the "identification of membrane-active regions of the ectodomain of the...

Hepatotoxic effects comparable for all ARVs.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- The drugs used to fight HIV infection all have comparable hepatotoxic effects. HIV patients "frequently present with elevated levels of serum transaminases (alanine aminotransferase [ALT] and/or...

Impact of HCV coinfection on risk of HAART-induced liver damage reviewed.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- The impact of HCV infection on the risk of HAART-induced liver damage has been reviewed. "Drug-induced liver injury (DILI) is the elevation of liver enzyme and/or bilirubin levels caused by the use...

Mitochondrial-to-nuclear DNA ratio may mark mitochondrial toxicity.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- The ratio of mitochondrial DNA to nuclear DNA may mark mitochondrial toxicity in nucleoside-treated HIV patients. "Nucleoside analogues inhibit human DNA polymerase gamma. As a result, they can...

NIH grant to fund drug development for multidrug-resistant HIV.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Chimerix, Inc., a biotechnology company developing orally available, targeted medicines for the treatment of smallpox, multidrug-resistant HIV and hepatitis virus infections, has been awarded a Phase I...

Routine resistance testing can improve ART outcome in experienced patients.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Routine resistance testing can improve the outcome of ART in heavily-treated HIV patients. According to recent research from the United States, the "long-term efficacy of making resistance testing...

Untimed drug levels powerful tool for measuring treatment compliance.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Untimed drug levels are a powerful tool for measuring compliance with anti-HIV treatment. In a recent study, scientists in the United States "examined cross-sectionally the relationship between...

HIV p24 antigen test can detect subtype G strains.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- The p24 antigen HIV test can detect subtype G strains. "The expense of PCR testing limits diagnosis of HIV infection in infancy in low resource settings," scientists in South Africa explained. ...

Antiretroviral therapy does not prevent HPV-induced genital lesions.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Antiretroviral therapy does not protect HIV+ women against the effects of HPV infection. In a study from Italy, the "effect of antiretroviral therapy on the natural history of human papillomavirus...

Vitamin A supplements may increase risk of vertical HIV transmission.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Vitamin A supplements may increase the risk of vertical HIV transmission. According to recent research from the United States, "[m]icronutrient status has been associated with shedding of human...

IFN-alpha with ribavirin can suppress virus-specific immunity.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Treatment with interferon (IFN)-alpha and ribavirin may impair immune responses to non-HCV viruses. Anti-HCV treatment "combining IFN-alpha and ribavirin (IFN+R) has still poorly defined effects on...

Erythrocyte ghosts prolong plasmid DNA expression in the blood.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Erythrocyte ghosts prolong plasmid DNA expression in the blood. According to published research from South Korea, "this study reports the use of erythrocyte ghosts (EG) as a biocompatible nonviral...

Hepatitis A peptide covalently linked to liposomes.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- A hepatitis A peptide has been covalently linked to liposomes. "In this work we have studied the conjugation of the immunogenic peptide sequence (110-121) belonging to the VP3 capsid protein of...

Bacteriophage-mediated nucleic acid immunization offers benefits.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Bacteriophage-mediated nucleic acid immunization offers benefits over naked DNA vaccines. "Whole bacteriophage lambda particles, containing reporter genes under the control of the cytomegalovirus...

Infection rate in a Midwestern community is dependent on the country of origin.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- A new study has examined the prevalence of the hepatitis B virus (HBV) in a small Midwestern population and found that immigrants from HBV-endemic parts of the world made up the majority of cases. ...

Nabi to supply Novaplus Nabi-HB.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Nabi Biopharmaceuticals (NABI) has signed an agreement with Novation, LLC, to supply Nabi-HB, [Hepatitis B Immune Globulin (Human)] through Novation's Novaplus Private Label Program. Novaplus, the...

Newly identified pathways reveal molecules that effect HBV inhibition.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Newly identified pathways reveal molecules that effect HBV inhibition. "The replication of hepatitis B virus (HBV) in hepatocytes is strongly inhibited in response to interferon (IFN)-alpha/beta and...

New York's refusal to treat hepatitis C patients continues to draw criticism.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- New York's refusal to treat short-term prison inmates infected with hepatitis C does not jeopardize their ultimate chances of beating the disease, the state prison system's top doctor told skeptical...

No "safe" level of alcohol use for patients with hepatitis C.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- A number of studies have indicated that heavy alcohol consumption contributes to the progression of chronic hepatitis C virus (HCV); however, light alcohol intake has not been shown to have the same...

Uniquely tagged NS5B identifies specific inhibitors of HCV polymerase.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Uniquely tagged NS5B identifies specific inhibitors of HCV polymerase. According to published research from Canada, "the interaction of the hepatitis C virus (HCV) RNA-dependent RNA polymerase with...

Older age at acquisition makes viral hepatitis progress faster.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Older age at acquisition makes viral hepatitis progress faster. According to scientists writing in the journal Epidemiology and Infection, "we investigated whether there are differences between the...

Cells expressing herpesvirus entry mediator C are resistant to pseudorabies.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Transformed cell lines expressing a soluble form of porcine herpesvirus entry mediator C exhibit resistance to pseudorabies virus infection. According to published research from Japan, "Porcine...

Common virus may contribute to uncommon bone disease in children.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- A common virus may play a major role in causing a painful disease of immune cells that attacks children's bones, according to a new study. The research may eventually lead to an easier diagnosis and...

Researchers propagate infectious HPV16.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Researchers develop a technique that allows the study of human papillomavirus type 16 (HPV16) and its connection to squamous cell cancer of the cervix, head and neck. "HPV16 infection is a major...

Effects of morphine on HIV gp160-induced monocyte apoptosis clarified.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- The effects of morphine on HIV gp160-induced monocyte apoptosis have been clarified. In a recent study, neuroimmunologists in New York examined "the effect of HIV-l gp160 protein and morphine on...

Similarities between HIV infection and aging may aid fight against both.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Immunological similarities between HIV infection and aging may point to strategies for ameliorating both conditions. "Aging and HIV disease show certain immunological similarities," scientists in...

Global flu outbreak could be curbed by worldside stockpile of antiviral drugs.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- New antiviral drugs could help slow or avert a deadly flu pandemic, but they are in such short supply that a major effort is needed to create an international stockpile, a U.N.-sponsored meeting of...

Rhode Island doctor found guilty of diluting vaccines.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- A Cranston, Rhode Island, doctor has been found guilty of product tampering and altering drugs for diluting vaccines he administered to his immigrant patients. A United States federal jury on March...

MMH Malarex yields positive results in study vs. established antimalarial drug.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Millenia Hope, Inc., (MLHP) stated that the results of a comparative test involving Millenia's MMH Malarex, an all-natural antimalarial agent with no parasitic resistance, and Camoquine, a chloroquine...

Replication kinetics of Chimerivax-DEN in Aedes aegypti determined.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Replication kinetics of the Chimerivax-DEN 1, 2, 3, 4 tetravalent virus mixture in Aedes aegypti were determined using real-time reverse transcriptase-polymerase chain reaction. According to recent...

Bone marrow cells guide brain-derived neurotrophic factor genes into the brain.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Bone marrow cells guide brain-derived neurotrophic factor genes into the brain. "Brain-derived neurotrophic factor (BDNF), a member of the neurotrophin family, is protective in animal models of...

Human glial fibrillary acidic promoter regulates transgenes in the brain.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Human glial fibrillary acidic promoter regulates transgenes in the brain. "The ability to regulate transgene expression will be crucial for development of gene therapy to the brain. The most...

Sick Las Vegas travelers prompt hotels to step up cleanliness.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Downtown Las Vegas hotels are stepping up sanitation efforts after the number of people who reported being sickened by a virus during visits over the past 4 months climbed past the 1,000 mark. Most...

Doctors call for balancing of patient/worker viral transmission protection.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Health care staff are at a much higher risk of acquiring viral infections from infected patients than vice versa. These viral infections include HIV and hepatitis. Despite this, patients receive...

Double-ablated adenovirus has an affinity with tumor targets.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Double-ablated adenovirus has an affinity with tumor targets. "To create tumor-targeted adenovirus (Ad) vectors, ablation of native CAR and integrin receptor binding is crucial to enhance the...

Bosko Djordjevic elected to board of directors.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Lipid Sciences, Inc., (LIPD) announced that Bosko Djordjevic was elected to the board of directors on March 2, 2004. Lipid Sciences is a development-stage biotechnology company engaged in the...

Controversial polio vaccines are safe, Nigerian president says.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Independent tests on controversial polio vaccines used in Nigeria show they are safe, Nigeria's president said March 17, 2004, in a bid to ease Muslim fears the vaccines are contaminated with HIV and...

Pressure treatment reduces infectivity of prions.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Pressure treatment at 60 degrees C reduces the proteinase K resistance and infectivity of prions. "High hydrostatic pressure is a mild technology compared with high temperatures and is commonly...

ERK-1/2 activation is a prerequisite for respiratory synctial virus infection.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- ERK-1/2 activation is a prerequisite for respiratory synctial virus infection. According to recent research published in the journal FEBS Letters, "respiratory syncytial virus (RSV) infection...

Recombinant Sendai virus delivers genes to human airway epithelium.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Recombinant Sendai virus delivers genes to human airway epithelium. "Recombinant Sendai virus (rSeV) infects respiratory epithelial cells in animal models and cultures of undifferentiated human...

Company announces an upgrade to ISO 9001:2000 certification.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- MedMira, Inc., (MIR) has received an upgrade to ISO 9001:2000 certification and has successfully completed its annual ISO 13485 audit. These certifications identify MedMira as having attained the...

Local gene therapy and immunosuppression promote osteoinductive activity.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Local gene therapy and immunosuppression promote osteoinductive activity. "We have previously utilized a human bone morphogenetic protein-2 (BMP-2)-expressing recombinant adenoviral vector...

Orally active fusion inhibitor of respiratory syncytial virus developed.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Scientists have developed an orally active fusion inhibitor of respiratory syncytial virus. According to recent research from the United States, "BMS-433771 was found to be a potent inhibitor of...

Functional receptor used by SARS coronavirus identified.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- The functional receptor used by the SARS coronavirus (CoV) has been identified. In a recent study, scientists in China "expressed a series of truncated spike (S) glycoproteins of SARS-CoV and found...

Health communication during SARS outbreak described.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- The health communication during the SARS outbreak is described in a recent issue of Emerging Infectious Diseases. According to research from the United States, " Experience with the outbreak of...

Lack of SARS transmission observed among public hospital workers in Vietnam.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- SARS transmission did not occur among health care workers at a public hospital in Vietnam. According to a study from the United States, "Vietnam was one of the first countries affected by the global...

SARS preparedness checklist developed for state and local health officials.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Researchers have developed a SARS preparedness checklist for state and local health officials. "In March 2003, the number of cases of severe acute respiratory syndrome (SARS) was increasing daily...

Study confirms transmission of retrovirus.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- African ape hunters are being infected by the same class of viruses that causes AIDS, scientists say, raising fears of a possible epidemic of a new disease in the future. The finding was the first...

Methylene blue virus photoinactivation reviewed.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- The use of MB photoinactivation to remove viral blood product contamination has been reviewed. Scientists in Alabama examined "the current status of the use of methylene blue (MB) photoinactivation...

BK polyoma virus infection plagues renal transplant recipients in India.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- BK polyoma virus infection plagues renal transplant recipients in India. "BK polyoma virus causes allograft dysfunction as a result of tubulo-interstitial nephritis in 2% to 5% of renal transplant...

Valaciclovir treats chronic hepatitis B after lung transplantation.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Valaciclovir treats chronic hepatitis B after lung transplantation. According to researchers in Switzerland, "we report on a chronic asymptomatic hepatitis B surface antigen (HBsAg) carrier who...

Vaccinia virus infections treated with ether lipid esters of cidofovir.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Cowpox and vaccinia virus infections in mice were treated with ether lipid esters of cidofovir. According to recent research from the United States, "Four newly synthesized ether lipid esters of...

FV-based SIN vectors could potentially produce replication-competent revertants.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- FV-based SIN vectors could potentially produce replication-competent revertants. According to a study from Germany, "self-inactivating (SIN) retroviral vectors based on feline foamy virus (FFV) were...

Hepatitis delta virus probably harbors at least seven major clades.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Hepatitis delta virus probably harbors at least seven major clades. "Hepatitis D virus (HDV) is a satellite of hepatitis B virus (HBV) for transmission and propagation and infects nearly 20 million...

South African duck hepatitis B virus isolates share Western signatures.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- South African duck hepatitis B virus isolates share Western signatures. According to recent research from South Africa, "the objective of the study was to characterize the genome of duck hepatitis B...

DNA repair enzyme PK prevents adeno-associated virus DNA integration.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- The DNA repair enzyme PK prevents adeno-associated virus DNA integration. "Recent studies have shown that recombinant adeno-associated virus (rAAV) can persist in episomal form; however, factors...

Ion pockets on the HCV IRES IIId domain identify targets for inhibition.
April 6, 2004... 2004 APR 6 - (NewsRx.com & NewsRx.net) -- Ion pockets on the HCV IRES IIId domain identify targets for inhibition. "The dynamic behavior of the HCV IRES IIId domain is analyzed by means of a 2.6-ns molecular dynamics simulation, starting...

Bone marrow features in AIDS patients characterized.
April 13, 2004... 2004 APR 13 - (NewsRx.com & NewsRx.net) -- The clinical features of bone marrow in contemporary and historical AIDS cohorts have been characterized. In a recent study, scientists in the United States "compared bone marrow findings in two...

The Fas ligand system is significant to chronic hepatitis B-linked liver injury.
April 13, 2004... 2004 APR 13 - (NewsRx.com & NewsRx.net) -- The Fas ligand system is significant to chronic hepatitis B-linked liver injury. According to a study from South Korea, "cytotoxic T lymphocytes are essential components of immune responses during...

Fruit flies used in fight against flu and fevers.
April 13, 2004... 2004 APR 13 - (NewsRx.com & NewsRx.net) -- West Nile virus and dengue fever, two of the most feared diseases spread by mosquitoes and other biting insects, could be controlled in the future by using techniques learned from studying the...