Medical Letter on the CDC & FDA articles from August 2008

Medical Letter on the CDC & FDA archives from August 2008

Study findings from Northwestern University, Medical Department provide new insights into vasculitis.
August 3, 2008... According to a study from the United States, "For patients with systemic vasculitis (SV) refractory to conventional therapy, new treatment strategies aimed at aggressive induction of remission and relapse prevention are being sought. We herein...

Study findings from United States Army Medical Research Institute of Infectious Disease broaden understanding of smallpox therapy.(Report)
August 3, 2008... Scientists discuss in 'Evaluation of orally delivered ST-246 as postexposure prophylactic and antiviral therapeutic in an aerosolized rabbitpox rabbit model' new findings in smallpox. "Orthopoxviruses, such as variola and monkeypox viruses, can...

Studies from E. Palomeras and co-researchers update current data on angiology.
August 3, 2008... In this recently published article, scientists in Mataro, Spain conducted a study "To analyze the clinical, etiologic and prognostic pro. le of anterior choroidal artery (AChA) infarcts. 42 consecutive patients with AChA infarction were...

Research reports on dementia from A.J. Lerner and colleagues provide new insights.
August 3, 2008... "Memantine is approved by the US Food and Drug Administration for the treatment of moderate to severe Alzheimer disease (AD). We investigated the frequency and variables associated with its use in mild to moderate/severe AD as defined by...

Studies from S. Delgado et al in the area of hemorrhagic fever described.
August 3, 2008... According to recent research from Cochabamba, Bolivia, "A small focus of hemorrhagic fever (HF) cases occurred near Cochabamba, Bolivia, in December 2003 and January 2004. Specimens were available from only one fatal case, which had a clinical...

Mosquitoes Are out in Full Force This Summer.
August 3, 2008... Mosquitoes top the list of summer pest concerns according to research from the National Pest Management Association (NPMA). This summer's mosquito season is no exception due to reports of increased mosquito populations and West Nile Virus (WNV)...

Reports from Harvard University, Medical Department advance knowledge in dementia.
August 10, 2008... "Atypical antipsychotic drugs have been used off label in clinical practice for treatment of serious dementia-associated agitation and aggression. Following reports of cerebrovascular adverse events associated with the use of atypical...

Researchers from New York University provide details of new studies and findings in the area of life sciences.
August 10, 2008... "Pipeline Previews brings to you information on the newest drugs and medical products as they become available to the dermatological community," scientists writing in the Journal of Drugs in Dermatology report (see also Life Sciences). ...

Study findings from C.H.D.R. Serra et al broaden understanding of pharmacokinetics.(Clinical report)
August 10, 2008... "Zidovudine is a thymidine nucleoside reverse transcriptase inhibitor with activity against HIV type 1. Some (similar to 8) generic formulations of zidovudine are available in Brazil; however, based on a literature search, information...

Data on leukemia clinical trial published by investigators at Center for Drug Evaluation and Research.(Report)
August 10, 2008... New research, 'FDA drug approval summary: nelarabine (Arranon) for the treatment of T-cell lymphoblastic leukemia/lymphoma,' is the subject of a report. In this recent report, researchers in the United States conducted a study "To describe the...

Recent findings from Center for Drug Evaluation and Research highlight research in leukemia clinical trial.
August 10, 2008... Scientists discuss in 'FDA drug approval summary: nelarabine (Arranon) for the treatment of T-cell lymphoblastic leukemia/lymphoma' new findings in leukemia. In this recently published article, scientists in the United States conducted a study...

Study results from University of Virginia in the area of enzyme research published.(Report)
August 10, 2008... "Legionella pneumophila expresses two peroxide-scavenging alkyl hydroperoxide reductase systems (AhpC1 and AhpC2D) that are expressed differentially during the bacterial growth cycle. Functional loss of the postexponentially expressed AhpC1...

Researchers at University of Miami, Medical Department release new data on yersinia.
August 10, 2008... "Yersinia spp. use a type 3 secretion system (T3SS) to directly inject six proteins into macrophages, and any impairment of this process results in a profound reduction in virulence. We previously showed that the exoribonuclease polynucleotide...

Research on cancer described by F. Trotta and colleagues.(Report)
August 17, 2008... According to a study from Rome, Italy, "The aim of this study is to assess the use of interim analyses in randomised controlled trials (RCTs) testing new anticancer drugs, focussing on oncological clinical trials stopped early for benefit. All...

New life sciences data have been reported by researchers at Creighton University.
August 17, 2008... According to a study from the United States, "Certain useful pharmaceutical agents carry a high risk of embryopathy. The US Food and Drug Administration (FDA), in cooperation with drug manufacturers, has established pregnancy prevention...

Season for West Nile Virus/EEE Reportings Begin; Mosquito Vacuum Helps Reduce Backyard Mosquito Population.
August 17, 2008... Late summer and early fall are prime seasons for the detection and reporting of mosquito-borne illnesses like West Nile Virus and EEE by health departments and mosquito control boards. (Editor's note: click here for a list of 2008 cases...

Research in the area of cancer therapy reported from Xavier University of Louisiana, College of Pharmacy.
August 17, 2008... New investigation results, 'Alternate delivery route for amifostine as a radio-/chemo-protecting agent,' are detailed in a study published in The Journal of Pharmacy and Pharmacology. "Amifostine (ethiofos, WR-2721) is an organic thiophosphate...

Research from J.A.S. Lie and colleagues provide new insights into cancer.
August 17, 2008... According to a study from Oslo, Norway, "The influence of occupational exposure to ionizing radiation on risk, of radiation-related cancers was studied among Norwegian nurses. A cohort of 43316 nurses who graduated between 1914 and 1984, and...

Findings in plague reported from A.P. Wilder and co-researchers.
August 17, 2008... According to recent research published in the journal Vector - Borne and Zoonotic Diseases, "Plague, caused by the bacterium Yersinia Pestis, often leads to rapid decimation of black-tailed prairie dog colonies. Flea-borne transmission of Y....

Research conducted at University of California has provided new information about plague.(Report)
August 17, 2008... According to recent research from the United States, "Plague, the disease caused by the bacterium Yersinia pestis, can have devastating impacts on black-tailed prairie dog (Cynomys Indovicianus) colonies. One suggested mechanism behind sporadic...

Researchers from Wichita State University describe findings in west nile virus.
August 17, 2008... "We conducted serological studies, using epitope-blocking ELISAs directed at West Nile virus (WNV) and flavivirus antibodies, of wild birds in south-central Kansas, the first for this state, in the winters of 2003-04 through 2005-06....

Research from W.H. Meeraus and colleagues provide new insights into life sciences.(Report)
August 17, 2008... Current study results from the report, 'Field comparison of novel and gold standard traps for collecting Aedes albopictus in Northern Virginia,' have been published. "Aedes albopictus is a potential West Nile virus bridge vector in Northern...

Urologists Should Recognize the Cardiac Safety of Prescribed Medications, Article Concludes.
August 24, 2008... A paper published in the current issue of Reviews in Urology (2008; 10(2):85-91) concludes that urologists and other physicians treating benign prostatic hyperplasia (BPH) should prescribe medications that do not affect the heart's electrical...

Researchers from American University discuss findings in life sciences.
August 24, 2008... According to a study from the United States, "This Article explores the evolution and interaction of the legal and cultural categories 'food'' and ''drug'' from the late nineteenth century to the Present. The federal statutory definitions of...

Research on regulatory actions reported by scientists at University of Washington.
August 24, 2008... According to recent research from the United States, "The zebrafish is a valuable model for studying hair cell development, structure, genetics, and behavior. Zebrafish and other aquatic vertebrates have hair cells on their body surface...

Findings in regulatory actions reported from Center for Devices and Radiological Health.
August 24, 2008... Fresh data on regulatory actions are presented in the report 'U.S. Food and Drug Administration and off-label use of expandable metal biliary stents within the peripheral vasculature.' According to recent research from the United States,...

New breast cancer screening study findings have been published by I. Carelli and colleagues.
August 24, 2008... "Evaluation of the knowledge, attitude and practice of breast self-examination in different groups of women in Sao Paulo. Application of a questionnaire to 392 women divided in four groups," researchers in Sao Paulo, Brazil report (see also...

New findings in legionnaire disease described by P.Y. Yu and co-researchers.(Report)
August 24, 2008... "The major sources of Legionnaires' disease (LD) are the potable water systems of large buildings including hospitals, nursing homes, and hotels. Culturing the hospital water system for Legionella allows a preventive approach for...

Studies from D.J. Salkeld and colleagues provide new data on plague.
August 24, 2008... According to recent research published in the Journal of Parasitology, "Plague, the disease caused by the bacterium Yersinia pestis, can have devastating impacts on North American wildlife. Epizootics, or die-offs, in prairie dogs (Cynomys...

New findings reported from S.G. Chrysant and co-authors describe advances in hypertension.
August 31, 2008... According to a study from the United States, "The incidence of hypertension continues to increase worldwide and, according to recent estimates, its incidence is approximately 30% of the U.S. However, the control of blood pressure (BP) to...

Research on immunoassay discussed by T. Urakami and co-researchers.(Report)
August 31, 2008... "The aim of this study was to develop a simpler and more rapid analytical method for unbound teicoplanin in serum. A new analytical method was developed by modifying an existing fluorescence polarization immunoassay (FPIA) method,"...

Reports summarize life sciences research from R.G. Wenzel and co-authors.
August 31, 2008... According to recent research from the United States, "Scientific issues and clinical implications associated with the use of biosimilars (biopharmaceuticals that are similar to an innovator product, notwithstanding minor differences) are...

New monoclonal antibodies study findings recently were reported by researchers at University of North Texas.(Clinical report)
August 31, 2008... " The relatively recent introduction of biological agents to treat psoriasis presents clinicians with the need to objectively compare and contrast these agents to allow more effective treatment of their patients. Objectives To evaluate and...

Studies conducted at University of Pittsburgh on regulatory actions recently published.
August 31, 2008... "A process is described for formulary revisions consistent with the Food and Drug Administration (FDA)'s current initiative to ensure that all drugs marketed in the United States have been approved for safety and efficacy. A list of pre-1938...

Studies from K. Ziebell et al provide new data on Escherichia coli.(Report)
August 31, 2008... According to a study from Lethbridge, Canada, "In this study, the association between genotypic and selected phenotypic characteristics was examined in a collection of Canadian Escherichia coli O157:H7 strains isolated from humans and cattle in...

Researchers from Toho University provide details of new studies and findings in the area of legionnaire disease.
August 31, 2008... "We analyzed the effects of temperature on the interaction of Legionella pneumophila with Acanthamoeba castellanii," scientists writing in the journal Applied and Environmental Microbiology report (see also Legionnaire Disease). "At ...