Cancer Weekly articles from September 2003

Cancer Weekly archives from September 2003

Tumor and drug-resistant genomes can be shaped by instability and selection.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Tumor and drug-resistant genomes can be shaped by instability and selection. According to a study from the United States, "Tumors with defects in mismatch repair (MMR) show fewer chromosomal changes...

COX-2 causes prostaglandin E2 to modulate pancreatic cancer angiogenesis.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- COX-2 causes prostaglandin E2 to modulate pancreatic cancer angiogenesis. "In some cancers cyclooxygenase (COX) inhibition appears to be anti-mitogenic and anti-angiogenic, but the actions of...

Egr-1 inhibition reverses the transformation of prostate cancer cells.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Egr-1 inhibition reverses the transformation of prostate cancer cells. According to recent research published in the journal Oncogene, "transcription factor early growth response-1 (Egr-1) is a...

Childhood survivors not receiving radiation have same life expectancy as general population.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- A new study from St. Jude Children's Research Hospital indicates that survivors of childhood acute lymphoblastic leukemia (ALL) who have not received radiation treatment as part of their therapy have...

Delaying chemotherapy could be best treatment option.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Delaying chemotherapy until symptoms develop for patients with asymptomatic advanced low-grade non-Hodgkin lymphoma is confirmed as an appropriate strategy, say authors of a U.K. study. ...

Novel targets for aberrant methylation in pancreatic carcinoma found.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Novel targets for aberrant methylation in pancreatic carcinoma are found. "To identify potential targets for aberrant methylation in pancreatic cancer, we analyzed global changes in gene expression...

Chronic zinc oversupply may play a role in prostate carcinogenesis.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Chronic zinc oversupply may play a role in prostate carcinogenesis. "The high concentration of zinc in the prostate suggests that zinc may play a role in prostate health," " scientists writing in...

Targeting TNF pathway along with ATRA may represent route to treat leukemias.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Targeting TNF pathway along with ATRA may represent route to treat leukemias. According to a study from Canada, "The nuclear receptor ligand all-trans retinoic acid (ATRA) causes dramatic terminal...

Novel 1,3,4-trisubstituted pyrazole derivatives stifle tumor growth mechanisms.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Novel 1,3,4-trisubstituted pyrazole derivatives stifle tumor growth mechanisms. According to recent research published in the journal Chemical & Pharmaceutical Bulletin, "several...

Swiss pharmaceutical group announces European drug submission for palonosetron.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Helsinn Healthcare, SA, a privately owned Swiss pharmaceutical group, announced the submission of their European drug application for palonosetron through the centralized procedure that will lead to the...

TSLC1 gene in human lung cancer is probably a cell adhesion molecule.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- The mouse ortholog of TSLC1, a tumor suppressor gene in human lung cancer, is found to be a cell adhesion molecule that may be expressed more to slow metastasis. According to recent research from...

FDA approves Photofrin for the ablation of high-grade dysplasia.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Axcan Pharma, Inc., announced that it has received approval from the U.S Food and Drug Administration (FDA) for the use of Photofrin photodynamic therapy (PDT) in the ablation of high-grade dysplasia...

Breast cancer, metastasis, growth reduced with i.v. bee venom therapy in murine model.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- In a mouse breast cancer model, intravenous but not intradermal bee venom reduced metastasis to lung. According to published research from Croatia, "The possible tumor growth-inhibiting and...

New screening for CAR reveals transfection efficiency in cancer cells.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- According to published research from the United States, "virus uptake is the first rate-limiting step for the successful gene delivery of any virus-based gene therapy. For adenovirus-based gene therapy,...

Diffusion-weighted imaging can detect bone marrow alterations.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Diffusion-weighted imaging can detect bone marrow alterations. "Diffusion-weighted imaging allows for measurement of tissue microstructure and reflects the random motion of water protons,"...

Nuclear medicine bone scan can give a potentially misleading appearance.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Nuclear medicine bone scan can give a potentially misleading appearance. According to a study from the United States, "Nuclear medicine bone scan is an essential diagnostic imaging tool both for the...

Rotationplasty may be an effective partial limb salvage procedure.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Rotationplasty may be an effective partial limb salvage procedure. According to a study from South Korea, "In patients having malignant or aggressive bone tumors around the knee joint and requiring...

Zoledronic acid will improve patients' quality of life.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Zoledronic acid will improve patients' quality of life. "The two main therapeutic applications of bisphosphonates are tumor bone disease and osteoporosis," researchers in Belgium report. "They...

Company plans to increase sales of I-Plant prostate cancer seed.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Implant Sciences (IMX) announced that they will initiate a direct marketing and sales program to sell their I-Plant Seed brachytherapy seeds for use in the treatment of prostate cancer. This...

Welsh study set to accelerate search for new treatment.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Artificially creating brain cancer cells by manipulating normal brain cells in the lab could pave the way to new treatments for the disease, a Cancer Research UK study reveals. Using human brain...

Research: GliaSite RTS is a safe and effective treatment for brain tumors.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Proxima Therapeutics, Inc., a developer of site-specific radiation therapy systems for brain and breast cancer, announced publication of data from a multicenter study of its GliaSite Radiation Therapy...

Breast cancer screening should be encouraged by general practitioners.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Breast cancer screening should be encouraged by general practitioners. "Achieving and maintaining a high rate of attendance for screening and two-yearly rescreening is essential for the success of...

Duke University's hyperthermia treatment acquired.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Celsion Corporation has obtained exclusive rights to an advanced phased array radio frequency (RF) heating system designed specifically for use with chemotherapeutic drugs for the treatment of locally...

First component of rolling NDA submitted for RSR13.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Allos Therapeutics, Inc., (ALTH) announced that it has begun submission of a new drug application (NDA) to the U.S. Food and Drug Administration (FDA) for the company's investigational radiation...

Syngeneic stem cell grafts offer little improvement over autografts for breast cancer patients.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Syngeneic stem cell grafts offer little improvement over autografts for breast cancer patients. "Metastatic breast cancer has been a common indication for autologous hematopoietic stem cell...

Systemic redundancies may mask the effects of PAI-1 on cancer inactivation.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Systemic redundancies may mask the effects of PAI-1 on cancer inactivation. "The plasminogen activator inhibitor-1 (PAI-1) blocks the activation of plasmin(ogen), an extracellular protease vital to...

Trial tests treatment for postmenopausal cancer patients who relapse.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- AstraZeneca announced that patient recruitment has begun on an important new trial involving its novel estrogen receptor antagonist, "Faslodex" (fulvestrant). The trial, called EFECT, is designed...

De-epithelialized TRAM flaps are an alternative to autologous tissue use.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- De-epithelialized TRAM flaps are an alternative to use of autologous tissue in breast implantation surgery. "Since the 1980s, many patients have benefited from the use of the transverse rectus...

Cytokine imbalances mark the pathogenesis of chronic lymphocytic leukemia.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Cytokine imbalances mark the pathogenesis of chronic lymphocytic leukemia. According to published research from Poland, "the serum concentration of two proangiogenic cytokines: basic fibroblast...

Antibody scFv fragments may be a nuclear delivery system in cancer cells.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Antibody scFv fragments may be a nuclear delivery system in cancer cells. "scFv fragments of a monoclonal antibody that penetrates living cells and localizes in nuclei were designed as fusion...

Diabody-based gene therapy represents a new strategy for cancer therapy.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Diabody-based gene therapy represents a new strategy for cancer therapy. "Infiltrating T cells are found in many malignancies, but they appear to be mostly anergic and do not attack the tumor,...

Prostate cancer invasion is influenced indirectly by TGF beta1 signals.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Prostate cancer invasion is influenced indirectly by TGF beta1 signals. According to a study from Turkey, "the effect of transforming growth factor (TGF) beta1 on the proliferation and plasminogen...

Carboxymethyl benzylamide dextran limits carcinomas in nude mice.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Carboxymethyl benzylamide dextran limits carcinomas in nude mice. "Vascular endothelial growth factor ( VEGF) expression is elevated in a wide variety of solid tumors. Inhibition of VEGF activity...

G-CSF raises GVHD but not mortality risk in matched sibling stem cell graft recipients.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Posttransplant G-CSF treatment raises the risk of GVHD - but not overall mortality - in recipients of matched sibling stem cell grafts. According to published research from Sweden, "the effect of...

Isolated limb perfusion is feasible for treating cancer and other diseases.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Isolated limb perfusion is feasible for treating cancer and other diseases. "Isolated limb perfusion with melphalan is the treatment of choice for multiple (small) melanoma-in-transit metastases....

Mitochondrial genes linked to tumor cell radiation resistance.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- A pair of mitochondrial genes have been linked to radiation resistance in malignant cells. "To identify genes that are differentially expressed in a methotrexate (MTX)-resistant cell strain...

PEDF gene transfer suppresses angiogenesis and tumor growth.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- PEDF gene transfer suppresses angiogenesis and tumor growth. According to recent research from Spain, "pigment epithelium-derived factor (PEDF) was identified from retinal pigment epithelial cells...

The gef gene blocks the growth of breast cancer cells.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- The gef gene blocks the growth of breast cancer cells. According to recent research from Spain, "the gef gene has cell-killing functions in Escherichia coli. To evaluate the feasibility of using...

Vascular integrins are targets for cancer containment.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Vascular integrins are targets for cancer containment. According to a study from Switzerland, "new blood vessel formation, a process referred to as angiogenesis, is essential for embryonic...

Antibody fragments fused to IL-12 and to TNF-alpha exert anti-tumor effect.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- The combination of a tumor-targeting antibody fragment fused to interleukin 12 and to tumor necrosis factor alpha exerts a synergistic effect against tumors. "The potent antitumor activity of...

Current developments in cancer vaccines and cellular immunotherapy reviewed.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Investigators have published a review on the current developments in cancer vaccines and cellular immunotherapy. "This article reviews the immunologic basis of clinical trials that test means of...

IL-6 fused to antibody increases immune response against ovarian cancer.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Interleukin-6 fused to an anti-idiotype antibody in a vaccine increases the specific humoral immune response against CA125+ (MUC-16) ovarian cancer "Anti-idiotypic (Id) monoclonal antibodies can...

MUC1-derived glycopeptides are strong antigens for breast cancer vaccines.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- MUC1-derived glycopeptide libraries with improved MHC anchors are strong antigens and prime mouse T cells for proliferative responses to lysates of human breast cancer tissue According to recent...

Peptide vaccine with adjuvant and CTLA-4 blockade elicits antitumor response.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- A protective antitumor immune response was elicited by cytotoxic T lymphocyte epitope peptide vaccination combined with CpG-oligodeoxynucleotide adjuvant and a CTLA-4 blockade. "Although peptide...

Endothelial cells overcome hypoxia-induced apoptosis because of CD105.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Endothelial cells overcome hypoxia-induced apoptosis because of CD105. According to a study from England, "CD105, a marker of endothelial cells, is abundantly expressed in tissues undergoing...

Genetically engineered plants produce vaccine components.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Researchers from Germany have genetically engineered plants to produce particles of human papillomavirus (HPV) that could be used in the creation of vaccines or as edible vaccines themselves. They...

Papillomavirus E7 protein blocks pCAF's acetyltransferase, a p53 coactivator.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Papillomavirus E7 proteins react with pCAF's acetyltransferase domain, normally a coactivator of the p53 transcription factor. According to a study from Canada, "Most cervical carcinomas express...

Circulating VEGF levels change in response to therapy for metastatic cancer.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Circulating VEGF levels change in response to therapy for metastatic cancer. According to recent research published in the International Journal of Biological Markers, "abnormally high blood levels...

Novel gene may be involved in CLL development.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- A novel gene may be involved in leukemia pathogenesis. Scientists in Greece described "the characterization of a new gene (E4.5) that maps at chromosome band 13q14.3, a chromosomal area frequently...

Chronic-phase CML patients respond to imatinib, but questions remain.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Chronic-phase CML patients respond to imatinib but response duration questions remain. According to recent research from the United States, "Imatinib mesylate (Gleevec, Glivec, formerly STI571;...

Three immunohistochemical stains help distinguish clear cell cancer as ovarian or renal.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Three immunohistochemical stains can help distinguish clear cell carcinoma origin as ovarian or renal. According to recent research published in the International Journal of Gynecological...

Binding sites for Lewis antigens are expressed by human colon cancer cells.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Binding sites for Lewis antigens are expressed by human colon cancer cells. "In colon cancer, endothelial cell selectins can promote tumor cell attachment via interactions with sialylated Lewis...

Immunochemical fecal occult blood testing can prevent advanced colorectal cancer.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Immunochemical fecal occult blood testing can prevent advanced colorectal cancer. According to a study from Japan, "To evaluate colorectal cancer screening with fecal occult blood testing (FOBT) in...

Moderate doses of vitamin B-6 suppress tumor growth in animal studies.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Moderate doses of vitamin B-6 suppress tumor growth in animal studies. "This review describes current research on the preventive effect of dietary vitamin B-6 against colon tumorigenesis and its...

Different genetic pathways may exist in the development of colorectal adenomas.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Different genetic pathways may exist in the development of colorectal adenomas. According to recent research from Germany, "Cytogenetic changes are widely unknown for nonpolypoid (synonymously...

Human Spy1 promotes survival of mammalian cells following DNA damage.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Human Spy1 promotes survival of mammalian cells following DNA damage. "Speedy (Spy1) is a novel cell cycle regulator that binds and activates cdk2, and was originally identified as a suppressor of...

Trio of AFP, PIVKAII, GGTII increases accuracy of liver cancer diagnosis.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Diagnosis of hepatocellular carcinoma is easier using not only alpha-fetoprotein, but protein induced by vitamin K absence and gamma glutamyl transferase as markers, too. "Serum protein induced by...

Primary ocular lymphoma is often diagnosed late, following brain metastasis.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Primary ocular lymphoma is often diagnosed late, following metastasis. According to recent research from the United States, "Primary ocular lymphoma involves the globe in the absence of any systemic...

PEDF could potentially treat a variety of angiogenesis-related disorders.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- PEDF could potentially treat a variety of angiogenesis-related disorders. According to a study from the United States, "blood vessel growth and stability are under the exquisite control of a network...

Primary duodenal carcinoma can show divergent growth patterns.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Primary duodenal carcinoma can show divergent growth patterns. "Primary duodenal adenocarcinoma accounts for less than 0.5% of all gastrointestinal cancers," scientists in the United States report....

Cold-inducible RNA-binding protein is downregulated in endometrial carcinoma.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- In the endometrium, cold inducible RNA binding protein may be involved in cell cycle control and its downregulation associated with endometrial cancer. According to a study from Japan,...

Retroperitoneal minimally invasive endoscopic adrenalectomy in children reviewed.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Retroperitoneal minimally invasive endoscopic adrenalectomy in children is reviewed. "Conventional adrenalectomy for tumor excision is one of the challenging tasks in adults as well as children with...

Black women still hardest hit by fatal breast cancer.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Breast cancer still is disproportionately deadly among black women, and a recent study shines some light onto reasons why that population may be less likely to have regular screenings for the disease....

Inflammatory pseudotumor due to clonal EBV-infected cells can occur in spleen.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Inflammatory pseudotumor due to clonal EBV-infected cells can occur in the spleen. According to a study from the United States, "We report a case of an inflammatory pseudotumor (IPT) of the spleen...

Immunology company reports financial results, discusses Aventis collaboration.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- ImmunoGen, Inc., (IMGN) announced financial results for the 3- and 12-month periods ended June 30, 2003. For the 3-month period, the company reported a net loss of $6.9 million, or $0.17 per basic...

Oncology drug maker reports 66% increase in revenue.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Aeterna Laboratories, Inc., (AEL; AELA) reported total revenues for the second quarter ended June 30, 2003, of $38.9 million, an increase of 66% compared with total revenues of $23.4 million for the...

The new nonviral GE7 vector system takes advantage of overexpressed receptors.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- The new nonviral GE7 vector system takes advantage of overexpressed receptors. According to a study from the Peoples Republic of China, "based on the fact that aberrant overexpression of some growth...

Visual-spatial deficits suitable for neurofibromatosis type-1 diagnosis.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Visual-spatial performance deficits can be used for the diagnosis of neurofibromatosis type-1 (NF1) in children. NF1 "is a common genetic disorder associated with a variety of medical...

Human Genome Sciences announces license agreement.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Human Genome Sciences, Inc., (HGSI) announced a license agreement with Genentech, Inc., (DNA). Under this agreement, Genentech has acquired exclusive, worldwide patent rights to develop and...

SLIT2 may be glioma tumor suppressor gene.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- SLIT2 may be a glioma tumor suppressor gene. "The SLIT family of genes consists of large extracellular matrix-secreted and membrane-associated glycoproteins," researchers in England explained. "The...

Endostatin also effective for head and neck cancer.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Researchers at Ohio State have found that endostatin has a dual effect on head and neck cancer cells - the compound prevented the cells from developing new blood vessels and also hindered the mechanism...

Acute myeloid leukemia responds to thalidomide in some patient cases.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Acute myeloid leukemia responds to thalidomide in some patient cases. "In analogy to solid neoplasms, accumulating data suggest the requirement of angiogenesis also for the development and...

Novel suicide fusion genes stem T cell reactions after transplantation.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Two novel suicide fusion genes stem T cell reactions after transplantation. "Donor lymphocyte infusions (DLI) following allogeneic stem cell transplantation are known to mediate...

Novel genetic hemophilia markers improve prenatal diagnosis.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- A series of novel genetic markers may improve prenatal hemophilia development. "The heterogeneous nature of the mutations, the size, and the complexity of the factor VIII gene makes direct mutation...

Researchers propose guidelines for liver imaging with multidetector CT.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Researchers propose guidelines for liver imaging with multidetector CT. "The speed and flexibility of multidetector computed tomography (MDCT) have led to improvements in liver imaging,...

Hepatocyte antigen may be a marker of intestinal metaplasia.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Hepatocyte antigen may be a marker of intestinal metaplasia. According to recent research published in the American Journal of Surgical Pathology, "Intestinal metaplasia is a histologic hallmark of...

Herpesvirus 8 infection linked to hepatitis B and HIV infections in Ugandans.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Human herpesvirus 8 infection was associated with hepatitis B and HIV infections in Ugandan blood donors. According to recent research from the United States, "Human herpesvirus 8 (HHV-8) is...

Cyclin E is overexpressed and amplified in many different human tumor types.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Cyclin E is overexpressed and amplified in many different human tumor types. According to published research from Switzerland, "Cyclin E amplification and overexpression have recently been described...

Interleukin-21 gene therapy activates perforin-dependent tumor immunity.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Interleukin-21 gene therapy activates perforin-dependent tumor immunity. According to recent research from the United States, "Interleukin (IL)-21 is a key factor in the transition between innate...

Shark cartilage protein stimulates antitumor immunity in murine models.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Shark cartilage protein stimulates antitumor immunity in murine models. "Shark cartilage has proven to have some inhibitory effects on angiogenesis, metastasis, cell adhesion and proteolysis. In...

Embryonal rhabdomyosarcoma can occur following liver transplant.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Liver transplant recipients have a risk of embryonal rhabdomyosarcoma growth following transplant immunosuppression. "Although an increased incidence of de novo malignancies is reported in...

Cancer research organization selects Blue Coat for secure proxy appliance.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Blue Coat Systems, Inc., (BCSI) announced that Cancer Research UK has selected the Blue Coat SG800 secure proxy appliance for high-performance web content filtering and content security across its...

Components of fibrinolytic pathways occur in situ in laryngeal cancer.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Components of fibrinolytic pathways occur in situ in laryngeal cancer. According to published research from Poland, "Malignancy is characterized by the occurrence of components of coagulation...

Tumors with a high proliferation index have a poor prognosis.
September 2, 2003... 2003 SEP 2 - (NewsRx.com & NewsRx.net) -- Tumors with a high proliferation index have a poor prognosis. "Microarrays for gene expression profiling are rapidly becoming important research tools for the identification of novel markers, for...