Cancer Weekly articles from October 2002

Cancer Weekly archives from October 2002

Each recurrence is sooner than the last, study shows.(bladder cancer)
October 1, 2002... 2002 OCT 1 - (NewsRx.com & NewsRx.net) -- A study by researchers at Washington University School of Medicine in St. Louis, Missouri has found that the number of months between recurrences of superficial bladder cancer progressively shortens...

Estrogen derivative defeats drug resistant cells in bone marrow cancer.
October 1, 2002... 2002 OCT 1 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - The estrogen derivative 2-methoxyestradiol can override drug resistance in multiple myeloma. The growth of multiple myeloma, a bone marrow cancer that...

New imaging technology can sense tanks, as well as cancer.
October 1, 2002... 2002 OCT 1 - (NewsRx.com & NewsRx.net) -- What does remote sensing for camouflaged enemy ground vehicles have to do with breast cancer diagnosis? By next year, perhaps plenty. Both find threats hidden in innocent clutter. The Office of...

Laboratory study explains clinical promise of antiangiogenesis cancer drug.
October 1, 2002... 2002 OCT 1 - (NewsRx.com & NewsRx.net) -- For nearly 5 years, doctors at the University of Michigan Comprehensive Cancer Center have noted promising cancer-slowing results from early clinical trials of a drug that lowers the level of copper in...

Down-regulation of cell signaling in HPV-infected cervical cells promotes malignancy.(human papillomavirus and cervical cancer)
October 1, 2002... 2002 OCT 1 - (NewsRx.com & NewsRx.net) -- A collaboration of scientists from Harvard Medical School and Brigham and Women's Hospital have uncovered a key genetic event in the progression of malignant cervical cancer - and a potential new...

Study of low-fat, high-fiber diet finds no effect on PSA levels in men over a 4-year period.(prostate-specific antigen)
October 1, 2002... 2002 OCT 1 - (NewsRx.com & NewsRx.net) -- A low-fat, high-fiber diet heavy in fruits and vegetables has no impact on PSA levels in men over a 4-year period and does not affect the incidence of prostate cancer, according to a study by...

Antisense technology may help reverse cisplatin-resistance.(bladder cancer)
October 1, 2002... 2002 OCT 1 - (NewsRx.com & NewsRx.net) -- Researchers in South Korea recently conducted a study "to determine the change of expression of Bcl2 in cisplatin-resistant bladder cancer cell lines and the reversibility of chemoresistance to...

Faslodex data published in Journal of Clinical Oncology.
October 1, 2002... 2002 OCT 1 - (NewsRx.com & NewsRx.net) -- Results from two clinical trials evaluating Faslodex (fulvestrant) Injection in treating advanced breast cancer in postmenopausal women with disease progression following antiestrogen therapy was...

Mortality not reduced by mammography, said University of Toronto study.
October 1, 2002... 2002 OCT 1 - (NewsRx.com & NewsRx.net) -- Women in their 40s who receive annual mammography screening do not have a better chance of surviving breast cancer than those who receive usual care from their personal physician, report University of...

NEJM features reports using imatinib mesylate in two life-threatening conditions.(New England Journal of Medicine)
October 1, 2002... 2002 OCT 1 - (NewsRx.com & NewsRx.net) -- Treatment with Novartis drug Gleevec (imatinib mesylate) resulted in a sustained reduction in tumor size (over 50%) in more than half of patients with advanced unresectable or metatastic...

Targeting enzymes that immortalize cancer cells: If they can't be turned off, try to round them up.
October 1, 2002... 2002 OCT 1 - (NewsRx.com & NewsRx.net) -- Discovery of a clever trick that cancer cells use to make themselves immortal may lead to a way to stop their unchecked growth, according to scientists at the University of California (UC) Berkeley. ...

More than 70% of adults with cancer use alternative therapies.
October 1, 2002... 2002 OCT 1 - (NewsRx.com & NewsRx.net) -- More than 70% of adult cancer patients in western Washington use alternative therapies and almost all report substantial improvements in well-being as a result of using alternative medicine, according...

Myriad Genetics reports financial results for fiscal 2002.
October 1, 2002... 2002 OCT 1 - (NewsRx.com & NewsRx.net) -- Myriad Genetics, Inc., (MYGN) reported total revenues increased to a record $53,836,499 for the year ended June 30, 2002, from $45,162,391 for fiscal 2001. This increase was due primarily to greater...

Drug protects fertility, offspring in mice after radiation exposure.(sphingosine 1-phosphate)
October 1, 2002... 2002 OCT 1 - (NewsRx.com & NewsRx.net) -- Scientists have discovered a drug that prevents sterility in female mice after exposure to ionizing radiation. Additional findings suggest that this is accomplished without yielding genetic damage...

Clofarex web site launched.
October 1, 2002... 2002 OCT 1 - (NewsRx.com & NewsRx.net) -- Ilex Oncology, Inc., (ILXO) announced the launch of www.clofarex.com. Clofarex (clofarabine), a second-generation nucleoside analogue, is currently being studied as a potential treatment for...

Pharmacyclics reports progress on confirmatory phase III trial with Xcytrin.
October 1, 2002... 2002 OCT 1 - (NewsRx.com & NewsRx.net) -- Pharmacyclics, Inc. (PCYC) announced that based on its recent meeting with the U.S. Food and Drug Administration (FDA), the company is able to move forward with its plans to begin a Phase III clinical...

NeoPharm initiates new global trial of IL13-PE38.(Brief Article)
October 1, 2002... 2002 OCT 1 - (NewsRx.com & NewsRx.net) -- NeoPharm, Inc., (NEOL) announced further progress in its clinical development program for IL13-PE38, NeoPharm's tumor-targeted agent. Enrollment has begun in the first global phase I/II clinical...

Michigan Blue Cross Blue Shield will pay for digital mammograms.
October 1, 2002... 2002 OCT 1 - (NewsRx.com & NewsRx.net) -- Although Michigan's largest insurer said it's not convinced that digital mammograms offer superior breast cancer detection, it has begun paying for the procedure. In July, the traditional Blue...

Protein found defective in nearly half of human cancer tissues.
October 1, 2002... 2002 OCT 1 - (NewsRx.com & NewsRx.net) -- Penn State College of Medicine researchers have identified a new target for anticancer therapeutics - km23/mLC7-1, a protein that helps to direct protein traffic in the cell. The Penn State team of...

Rad50 and the maintenance of genome stability studied in mutant mice.
October 1, 2002... 2002 OCT 1 - (NewsRx.com & NewsRx.net) -- Dr. John Petrini and colleagues have succeeded in creating the first mouse model of Rad50 deficiency, lending unprecedented insight into the in vivo function of this protein in maintaining genome...

Xyotax to be tested in recurrent, chemotherapy-resistant cancer.
October 1, 2002... 2002 OCT 1 - (NewsRx.com & NewsRx.net) -- Cell Therapeutics, Inc., (CTI) (CTIC) announced that the Gynecologic Oncology Group (GOG), a cooperative of many of the most prominent physicians and institutions in the United States, has activated a...

Bax gene therapy promotes apoptosis in pancreatic cancer cells.
October 1, 2002... 2002 OCT 1 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Stimulating programmed cell death, or apoptosis, may be one way to improve outcomes in patients with pancreatic cancer. Pancreatic cancer is one of the most...

Patent issued covering novel CpG oligonucleotides.(Brief Article)
October 1, 2002... 2002 OCT 1 - (NewsRx.com & NewsRx.net) -- Hybridon, Inc., (HYBN.OB) announced the issuance of U.S. Patent No. 6,426,334 claiming a novel class of CpG oligonucleotides for the treatment of cancer. "The issuance of this patent makes Hybridon...

Mobile business of U.S. Medical Development acquired.
October 1, 2002... 2002 OCT 1 - (NewsRx.com & NewsRx.net) -- Endocare, Inc., (ENDO), a developer of innovative diagnostic and treatment tools for cancer and other diseases, announced that it has executed a definitive agreement to acquire the mobile prostate...

Invasiveness correlates with angiogenesis in thymic epithelial tumors.
October 1, 2002... 2002 OCT 1 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Tumor angiogenesis can provide important information about invasion in thymomas and malignant thymic tumors. Derived from thymic tissues, thymomas are...

Therapeutically effective dendritic cells generated by progenipoietin.
October 8, 2002... 2002 OCT 8 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - Progenipoietin (ProGP-4) stimulated the proliferation of dendritic cells that have shown effectiveness against cancerous tumors, according to a report...

Capsaicin interferes with cell's ability to process oxygen.(skin cancer)
October 8, 2002... 2002 OCT 8 - (NewsRx.com & NewsRx.net) -- The pungent component that gives spicy chili peppers their punch may be able to knock out skin cancers as well, reports a team of researchers at the University of Texas M.D. Anderson Cancer Center. ...

Media focus on endostatin helped - not hurt.
October 8, 2002... 2002 OCT 8 - (NewsRx.com & NewsRx.net) -- Widespread media coverage of an untested but promising cancer therapy attracted patients to a phase I clinical trial whom researchers worried would have unreasonable expectations. Yet many of them were...

Vectors encoding for vasostatin stamp out cancer growth.
October 8, 2002... 2002 OCT 8 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Plasmids encoding for vasostatin can cripple tumor-associated angiogenesis and cancer growth. Angiogenic growth encourages solid tumor proliferation....

DNA and hepatitis B virus vaccine evaluated in colorectal cancer patients.
October 8, 2002... 2002 OCT 8 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - The jury is still out on whether or not DNA vaccines are effective cancer fighters. "Despite an abundance of preclinical data, relatively little is known...

Tumors smaller, vessels fewer when treated with antisense hyaluronan.(prostate cancer)
October 8, 2002... 2002 OCT 8 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Prostate cancer cells lacking the ability to secrete hyaluronan generate smaller tumors and less neovascularization than do those that can secrete hyaluronan....

Tandem molecule shows preference for some thyroid carcinomas.
October 8, 2002... 2002 OCT 8 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Thyroid-specific cell killing can be obtained with gene therapy encoding for a tandemly repeated promoter. The tandemly repeated minimal thyroglobulin (TG)...

Cancer pathway targeted by collaboration.
October 8, 2002... 2002 OCT 8 - (NewsRx.com & NewsRx.net) -- De Novo Pharmaceuticals, Ltd., The Northern Institute for Cancer Research at the University of Newcastle and Cancer Research Ventures Ltd are pleased to announce that they have entered into a...

Campaign launched to help chronically ill patients.(Alonzo Mourning's Rebound from Anemia campaign)
October 8, 2002... 2002 OCT 8 - (NewsRx.com & NewsRx.net) -- When basketball superstar Alonzo Mourning was diagnosed with a rare and life-threatening kidney disease nearly 2 years ago, he faced the toughest challenge of his life. What he didn't realize was...

Biotech company prepares to launch therapy for refractory breast cancer in the U.K.(Bioenvision )(Brief Article)
October 8, 2002... 2002 OCT 8 - (NewsRx.com & NewsRx.net) -- Biotechnology company Bioenvision is set to launch a major new weapon in the fight against breast cancer. Modrenal is a refractory breast cancer treatment, which will be used in cases where front...

Gene repairs damaged DNA.(BRCA2 gene)
October 8, 2002... 2002 OCT 8 - (NewsRx.com & NewsRx.net) -- Structural studies of the protein produced by the BRCA2 gene, which is implicated in the development of hereditary breast and ovarian cancers, reveal that the protein is intimately involved in repairing...

Genentech stock plummets after drug fails key test.
October 8, 2002... 2002 OCT 8 - (NewsRx.com & NewsRx.net) -- Shares of Genentech, Inc. plummeted after an announcement that a once-promising experimental breast cancer drug had failed a clinical trial. The South San Francisco-based company announced September...

Tamoxifen shows encouraging results for prevention, but risks still unclear.
October 8, 2002... 2002 OCT 8 - (NewsRx.com & NewsRx.net) -- Early findings from a randomized trial investigating the effectiveness of tamoxifen to prevent breast cancer are reported in the Lancet. Although tamoxifen reduced breast cancer incidence by a third...

Genomics company lowers prices on tissue samples.
October 8, 2002... 2002 OCT 8 - (NewsRx.com & NewsRx.net) -- Cancer researchers will be able to access a variety of common cancer tissue samples at reduced prices, according to a newly revamped price list from Asterand, the Detroit-based clinical genomics...

Doctors freezing away tumors.
October 8, 2002... 2002 OCT 8 - (NewsRx.com & NewsRx.net) -- Robin Imhof watched, fascinated, as her doctor stuck a needle into the dime-sized lump in her breast and pumped freezing gas through it. On a nearby ultrasound monitor, a round image gradually turned...

FDA grants priority review for Gleevec.
October 8, 2002... 2002 OCT 8 - (NewsRx.com & NewsRx.net) -- Novartis Oncology announced that Gleevec (imatinib mesylate) has been granted priority review by the U.S. Food and Drug Administration (FDA) for possible use as a first-line treatment for newly...

Eloxatin distribution begun.
October 8, 2002... 2002 OCT 8 - (NewsRx.com & NewsRx.net) -- Sanofi-Synthelabo (SNY) announced that it began distribution of Eloxatin (oxaliplatin for injection), a new chemotherapy drug for metastatic colorectal cancer, to oncologists' offices throughout the...

SBIR grant renewed for development of oral Amphotericin B.(Brief Article)
October 8, 2002... 2002 OCT 8 - (NewsRx.com & NewsRx.net) -- BioDelivery Sciences International, Inc., (BDSI; BDSIW) has received official notification of a second year award of $883,000 for their SBIR grant from the National Institutes of Health (NIH) to pursue...

Interleukin-2 safe for patients with low HHV-8 viremia.
October 8, 2002... 2002 OCT 8 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Supplemental interleukin-2 treatment is safe for most HIV patients coinfected with the virus responsible for Kaposi sarcoma, researchers in Italy say. "The...

Product R clinical trial results subject of published study.
October 8, 2002... 2002 OCT 8 - (NewsRx.com & NewsRx.net) -- Advanced Viral Research Corp. (ADVR) announced that the results of a randomized, controlled, and blinded clinical study of Product R therapy in patients with HIV/AIDS have been published in the journal...

Link to cervical lesions confirmed.(Brief Article)
October 8, 2002... 2002 OCT 8 - (NewsRx.com & NewsRx.net) -- Infection with human papillomavirus (HPV) is linked to an increased likelihood of cervical lesions in women, finds a study in the British Medical Journal. The study, which involved over 10,000...

Patent issued for dendritic cell activation.(Coley Pharmaceutical Group Inc.)
October 8, 2002... 2002 OCT 8 - (NewsRx.com & NewsRx.net) -- The U.S. Patent and Trademark Office has granted U.S. Patent No. 6,429,199, the 10th patent owned by or exclusively licensed to Coley Pharmaceutical Group, Inc., This patent covers the use of CpG...

U.S. patent granted for TAP-1 against all cancers.(GeneMax Corp. receives patent for use of its transporters associated with antigen processing)
October 8, 2002... 2002 OCT 8 - (NewsRx.com & NewsRx.net) -- GeneMax Corp. (GMXX; GX1) announced that it has received in the first quarter of 2002, a U.S. patent for the use of TAP-1 (transporters associated with antigen processing) as an immunotherapy against...

Patient recruitment, enrollment completed for Therafab.(Brief Article)
October 8, 2002... 2002 OCT 8 - (NewsRx.com & NewsRx.net) -- Antisoma, the U.K.-based biopharmaceutical company developing new drugs for cancer, has completed recruitment into a phase I trial of its radiolabeled monoclonal antibody fragment, TheraFab. The...

Hormone replacement therapy does not appear to influence breast cancer detection.
October 8, 2002... 2002 OCT 8 - (NewsRx.com & NewsRx.net) -- Taking hormone replacement therapy (HRT), does not diminish the ability to detect breast cancers or affect clinical outcomes for patients with breast cancer, according to an article published in the...

Raloxifene increases level of protein believed to inhibit estrogen-sensitive breast cancer.(Brief Article)
October 8, 2002... 2002 OCT 8 - (NewsRx.com & NewsRx.net) -- In a study supported by Eli Lilly and Co. and published in the September 2002 issue of Fertility and Sterility, researchers at Boston's Beth Israel Deaconess Medical Center, the Medical Center for...

Proteosome inhibitor PS341 represses myeloma in preclinical study.
October 8, 2002... 2002 OCT 8 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - The novel proteosome inhibitor PS-341 has extended survival in preclinical studies of human myeloma. Researchers announced in the September 2002 issue of...

Effect of diet on cancer risk studied.(Brief Article)
October 8, 2002... 2002 OCT 8 - (NewsRx.com & NewsRx.net) -- A review in the September 14, 2002, issue of the Lancet assesses the research on possible links between diet and cancer. A familiar conclusion is reached: Cancer risk can be reduced by eating a...

Hepatocyte growth factor antagonist controls spread of pancreatic tumors.
October 8, 2002... 2002 OCT 8 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Recombinant viruses encoding for the hepatocyte growth factor competitor NK4 can control the dissemination of pancreatic cancers in mice. Scientists think...

Wake Forest-Johns Hopkins team discovers gene.(Macrophage Scavenger Receptor 1 gene may be connected to prostate cancer susceptibility)
October 8, 2002... 2002 OCT 8 - (NewsRx.com & NewsRx.net) -- Scientists in the Center for Human Genomics at Wake Forest University School of Medicine and Johns Hopkins Medical Institutions have discovered a gene that "may play an important role in prostate cancer...

Cancer study may help plaintiffs in Motorola lawsuit.(cell phone/brain tumor link)
October 8, 2002... 2002 OCT 8 - (NewsRx.com & NewsRx.net) -- Attorneys for a doctor who was stricken by brain cancer are hoping a new study indicating a link between older cell phones and tumors will bolster a $800 million lawsuit against Motorola, Inc. and major...

Positive results reported on phase I trial of SAHA.(suberoylanilide hydroxamic acid)(Brief Article)
October 8, 2002... 2002 OCT 8 - (NewsRx.com & NewsRx.net) -- Aton Pharma, Inc., reported that it has obtained encouraging results from its phase I clinical trials with its lead product candidate, suberoylanilide hydroxamic acid (SAHA). SAHA, an inhibitor of...

High stem cell doses do not prevent T-cell depletion side effects.
October 8, 2002... 2002 OCT 8 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - The risks associated with T-cell depletion of allogeneic stem cell grafts cannot be overcome with high stem cell doses, researchers in Switzerland find. ...

Post-transplantation lymphoproliferative disorder relatively common but treatable.(autologous stem cell transplantation complications)
October 8, 2002... 2002 OCT 8 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Post-transplantation lymphoproliferative disorder (PTLD) is an under-recognized risk of autologous stem cell transplantation (ASCT), researchers in Canada warn....

Strategy for treating MUC1-expressing tumors depends upon tumor origin.
October 15, 2002... 2002 OCT 15 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - MUC1-expressing tumors that originate in different organs require different effector cells and mechanistic tactics for elimination, according to a...

Percutaneous ethanol injection therapy appropriate for use in the elderly.
October 15, 2002... 2002 OCT 15 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Older patients with primary liver cancer can benefit from percutaneous ethanol injection therapy (PEIT), researchers in Japan report. Due to the number of...

Research reveals a more complete picture of breast tissue.
October 15, 2002... 2002 OCT 15 - (NewsRx.com & NewsRx.net) -- A team of Dartmouth engineers and doctors is trying to find more comfortable and comprehensive ways to examine breast tissue to better detect and diagnose breast cancer. The Dartmouth group is...

New approach to replacing immune cells shrinks tumors in patients.
October 15, 2002... 2002 OCT 15 - (NewsRx.com & NewsRx.net) -- A new approach to cancer treatment that replaces a patient's immune system with cancer-fighting cells can lead to tumor shrinkage, researchers report in the journal Science. The study demonstrates...

Researchers develop first fully automatic method to track 3-D movement of cancer cells.
October 15, 2002... 2002 OCT 15 - (NewsRx.com & NewsRx.net) -- Cancer researchers know the disease spreads from organ to organ in a nonrandom pattern, but they are unable to predict exactly how cancer will spread, in part because of the limited tools available to...

Heart disease gene link found.
October 15, 2002... 2002 OCT 15 - (NewsRx.com & NewsRx.net) -- Researchers at Johns Hopkins, Wake Forest, and the National Human Genome Research Institute have implicated mutations in a "heart disease gene" in hereditary prostate cancer. The findings, which...

Obese women face higher colorectal cancer risk.
October 15, 2002... 2002 OCT 15 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - Obesity does increase the risk of colorectal cancer in premenopausal women, according to a report in the journal, Gut. "Several large studies of...

European Commission grants approval for Aranesp, Neulasta.
October 15, 2002... 2002 OCT 15 - (NewsRx.com & NewsRx.net) -- Amgen (AMGN) announced that the European Commission (E.C.) has approved both darbepoetin alfa (Aranesp/Nespo) for the treatment of anemia in adult cancer patients with solid tumors (nonhematological...

Elevated endostatin in glioma reflects attempt to counteract cancer growth.
October 15, 2002... 2002 OCT 15 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - High levels of endostatin found adjacent to vessels in gliomas may represent attempts to counteract tumor angiogenesis, researchers believe. Gliomas,...

50,000 sisters of women with breast cancer recruited for U.S. study.
October 15, 2002... 2002 OCT 15 - (NewsRx.com & NewsRx.net) -- At the September 2002 Tampa Bay-area Race for the Cure, medical researchers began recruiting women for a unique effort to determine the causes of breast cancer - the "Sister Study." Researchers hope to...

Neuropilin-1 a multifunctional protein for progression in breast cancer.
October 15, 2002... 2002 OCT 15 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Both conventional and novel genetic fingerprinting techniques have confirmed neuropilin-1 protein stimulates mechanisms associated with breast cancer...

New data published on novel mode of action of Modrenal.
October 15, 2002... 2002 OCT 15 - (NewsRx.com & NewsRx.net) -- Bioenvision, Inc., (BIOV) announced that new data on the novel mode of action of Modrenal has been published in Cancer Cell Biology. Modrenal is approved for marketing in the U.K. for the treatment...

Study looks at mammogram readings.
October 15, 2002... 2002 OCT 15 - (NewsRx.com & NewsRx.net) -- Radiologists examining mammogram X-rays gave false-positive cancer readings up to 15.9% of the time, with the youngest and most recently trained doctors having two to four times the false-positive rate...

Carboplatin plus low-dose antisense oligonucleotides slows tumor growth.
October 15, 2002... 2002 OCT 15 - (NewsRx.com & NewsRx.net) -- Combining the chemotherapeutic carboplatin with c-myc phosphorothioate antisense oligonucleotides significantly slowed adenocarcinoma tumor growth in a rodent model. "Phosphorothioate...

Researchers tackle brain tumor chemoresistance.
October 15, 2002... 2002 OCT 15 - (NewsRx.com & NewsRx.net) -- An experiment in which adenoviral transfer of antisense O6-methylguanine-DNA methyltransferase (MGMT) mRNA and ribozyme to glioma cells expressing the enzyme unfortunately resulted in minimal effect,...

Lidocaine inhibits cancer cell invasion.
October 15, 2002... 2002 OCT 15 - (NewsRx.com & NewsRx.net) -- Researchers in Japan reported that in their studies, the commonly used anesthetic lidocaine inhibited invasion of cancer cells. "Although the mechanism is unknown, infiltration anesthetics are...

PrimaBioMed achieves clinical advancement and patent expansion in 2002.
October 15, 2002... 2002 OCT 15 - (NewsRx.com & NewsRx.net) -- PrimaBioMed, Ltd., the cancer and immunotherapy research and therapeutic development company, reviewed fiscal 2002, its first full year as a public company. CEO Marcus Clark commented that 2002 was...

Pentrix vaccine trial advances to evaluation stage.
October 15, 2002... 2002 OCT 15 - (NewsRx.com & NewsRx.net) -- Australian Cancer Technology (AustCancer) (ACU) has announced that the phase 1b/2a clinical trial of the Pentrix anticancer vaccine, being undertaken at St Vincent's Hospital, Sydney, has advanced to...

Tumor cells overexpressing heat shock protein effectively inhibit murine colon cancer growth.
October 15, 2002... 2002 OCT 15 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - Growth of a murine CT26 colon carcinoma was completely inhibited by immunization of the mice with a vaccine containing a heat shock protein and cells...

Vaccine reduces metastases after laparotomy.(pulmonary metastases )
October 15, 2002... 2002 OCT 15 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - Perioperative stimulation of the immune system with a vaccine consisting of lysed adenocarcinoma cells and an adjuvant reduced the number of...

Therapy prevents neuropathic effects of cisplatin chemotherapy.(gene therapy)
October 15, 2002... 2002 OCT 15 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - The neuropathic effects of cisplatin chemotherapy can be combated with viral and nonviral gene therapies. Cisplatin is just one of several compounds...

Researchers discover new risk factor.(Bloom syndrome a new risk for colorectal cancer development)
October 15, 2002... 2002 OCT 15 - (NewsRx.com & NewsRx.net) -- A combination of mouse and human studies have revealed that people who are carriers of the rare disease Bloom syndrome are at increased risk for developing colorectal cancer. In two studies,...

Collaboration with Sanofi-Synthelabo on Eloxatin extended.(Debiopharm extends collaboration)
October 15, 2002... 2002 OCT 15 - (NewsRx.com & NewsRx.net) -- The Swiss-based pharmaceutical development company Debiopharm announced that it has extended its patent and know-how agreement on Eloxatin (oxaliplatin), currently indicated for advanced colorectal...

Cyclooxygenase-2 expression is upregulated in polyps.(colorectal cancer development research)
October 15, 2002... 2002 OCT 15 - (NewsRx.com & NewsRx.net) -- According to a study from the United States, "Cyclooxygenase-2 (Cox-2) is commonly upregulated during human colorectal tumorigenesis, and its contribution to this process has been clearly demonstrated...

Method of loading antigen onto dendritic cells affects immune response.
October 15, 2002... 2002 OCT 15 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - Directly fused dendritic cell-leukemia cell hybrids were the most effective promoters of antileukemia cytotoxic T lymphocyte (CTL) immune responses...