Cancer Weekly articles from November 2004

Cancer Weekly archives from November 2004

Anticancer effects of DADS characterized.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- The anticancer effects of diallyl disulfide (DADS) have been further characterized. DADS, "one of the major components of garlic (Allium sativum), is well known to have chemopreventative activity...

Study: Oleic acid could be a potential initiating carcinogen after epoxidation.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- University of Illinois researchers say oleic acid could be a potential initiating carcinogen after epoxidation of 17beta-estradiol, a mechanism they previously suggested results in breast cancer...

Protein biomarkers and drug design for cancer treatments reviewed.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Researchers review protein biomarkers and drug design for cancer treatments in a recent issue of the European Journal of Cancer Prevention. "The development of new cancer treatments is quickly...

Gene profiling can distinguish intestinal and diffuse carcinomas.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Gene expression profiling may be useful for differentiating between intestinal and diffuse gastic cancers. "Gastric cancer is the fourth leading cause of cancer-related death in the world,"...

KiSS-1 downregulation causes tumor invasion/worse prognosis in gastric cancer.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- KiSS-1 downregulation causes tumor invasion and a worse prognosis in gastric cancer. According to recent research from Japan, "KiSS-1 is a promising candidate tumor-suppressor gene and may play a...

FDA approves medical device to treat AAA.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Cook, Inc., a privately held medical-device manufacturer, announced that the U.S. Food and Drug Administration (FDA) has approved the company's next-generation solution for abdominal aortic aneurysms...

Loss of clone with FLT3 gene mutation at relapse does not improve AML prognosis.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- The loss of a clone with an FLT3 gene mutation at relapse does not improve the prognosis of acute myeloid leukemia. According to recent research from Germany, "Internal tandem duplications (ITDs)...

Combination therapy for liver cancer is linked to interstitial pneumonia.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Combination therapy for liver cancer is linked to interstitial pneumonia. According to recent research published in the Journal of Gastroenterology, "previously we reported combined...

Slightly increased risk of ischemic stroke found with tamoxifen.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Researchers at Duke University Medical Center have found a slightly elevated risk of ischemic stroke due to a blood clot in the brain in patients treated with tamoxifen, a drug commonly prescribed both...

Pharma company's long-term study of Celebrex expected to continue.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Pfizer Inc. said that three large long-term Celebrex (celecoxib capsules) studies involving more than 6,000 patients have not shown any significant safety issues and are expected to continue to...

Phase I trial of Hematide initiated.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Affymax, Inc., announced that it has initiated a placebo controlled, phase I dose-finding clinical trial with its lead product candidate, Hematide, a peptide-based erythropoiesis stimulating agent (ESA)...

Biotech company working to address problem of antibiotic resistance.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- New biotechnology company, RiboNovix, Inc., is addressing the worsening problem of antibiotic-resistant bacteria by developing new anti-infectives that are less susceptible to drug resistance. Over...

Oral fluconazole safe/effective empiric treatment for neutropenic fever.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Oral fluconazole is a safe and effective empiric treatment for persistent neutropenic fever. According to a study from Israel, "Neutropenic patients who continue to be febrile despite adequate...

Antiestrogenic drug combinations may be used for glioblastoma malignancies.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Antiestrogenic drug combinations may be used for glioblastoma malignancies. According to researchers in Turkey, "The antitumor activity of nonsteroidal antiestrogens on C6 and low passage of human...

CD45 plays significant role in nuclear apoptosis by chloride channel regulation.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- CD45 plays a significant role in nuclear apoptosis by chloride channel regulation. According to published research from Canada, "Mitochondrial-perturbating agents such as toxic compounds induce...

Humic acid induces apoptosis in premyelocytic leukemia HL-60 cells.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Humic acid induces apoptosis in promyelocytic leukemia HL-60 cells. According to a study from Taiwan, "It has been shown that humic acid (HA), a phenolic polymer, exhibits pro-oxidant and cytotoxic...

Nobel Prize awarded to researcher at cancer center.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Linda Buck, PhD, a member of Fred Hutchinson Cancer Research Center's Basic Sciences Division, was named winner of the 2004 Nobel Prize in physiology or medicine. She received the award for her...

Gli proteins up-regulate expression of basonuclin in basal cell carcinoma.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Gli proteins up-regulate the expression of basonuclin in basal cell carcinoma. "Tumorigenesis is frequently accompanied by enhanced rRNA transcription, but the signaling mechanisms responsible for...

Androgen receptor expression inversely correlates with pathologic, tumor stage.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Androgjen receptor expression is inversely correlated with pathologic, tumor stage in bladder cancer. Researchers in the United States conducted a study "to evaluate the expression of the androgen...

Molecular assessments can facilitate the management of bladder carcinoma.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Molecular assessments can facilitate the management of bladder carcinoma. According to published research from England, "hypoxia and proliferation are important determinants of radiation...

New risks for bladder cancer identified by MIT team.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- MIT researchers and colleagues have identified three new chemical risk factors for bladder cancer in a study involving some 600 people in the Los Angeles area. The work was reported in the Journal...

Gen-Probe signs licensing agreements.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Gen-Probe (GPRO) has signed nonexclusive licensing agreements with bioMerieux and its affiliates that provide bioMerieux options to access Gen-Probe's ribosomal RNA technologies for certain uses, and...

Brain metastases patients' radiographic response at 3 months predicts survival.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- For brain metastases patients undergoing whole brain radiation therapy (WBRT), radiographic response in the brain at 3 months is a statistically significant predictor of prolonged survival, according to...

Data on GliaSite Radiation Therapy System presented at ASTRO.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Proxima Therapeutics, Inc., announced encouraging results of a postmarket study on the GliaSite Radiation Therapy System as a first-line treatment for single resected brain metastasis. Each year,...

N-ethyl-N-nitrosourea increases brain mutations in neonatal mice.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- N-ethyl-N-nitrosourea (ENU) increased brain mutations in prenatal and neonatal mice but not in the adults. "The incidence of childhood cancer is increasing. One of the most common cancers for...

New findings from EFAPROXYN brain metastases trial releases.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Allos Therapeutics, Inc., (NASDAQ:ALTH) announced the presentation of new findings from its phase 3 clinical trial of the investigational radiation sensitizer EFAPROXYN (efaproxiral) in patients with...

Positive cancer data on ECO-4601 presented at symposium.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Ecopia BioSciences, Inc., (EIA) presented data on ECO-4601 in a poster entitled "A new antitumor compound, ECO-4601: Preclinical evaluation and in vivo efficacy in glioma" at the European Organization...

Protein protecting brain from toxins also blocks some chemotherapy.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- St. Jude studies showing that Mrp4 limits penetration of topotecan suggest that blocking this protein might increase access of anticancer drugs to tumor sites and improve treatment of brain cancer ...

Analysis: New York City women continue to receive fewer mammograms.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Women in New York City continue to receive mammograms at much lower levels than those outside the downstate region, while Kings County (Brooklyn) still has the lowest county-specific mammography rate,...

Breast density, second breast cancer in women with ductal carcinoma studied.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Having highly dense breasts may be associated with an increased risk of a second breast cancer among women who have had a ductal carcinoma in situ (DCIS), according to a study in the October 6 issue of...

CORI calls for increased awareness of link between obesity, breast cancer.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Statistics from the American Obesity Association show that obese women are more likely to die of breast cancer than women of healthy weight and that after menopause these women have a higher risk of...

China's FDA approves laser breast imaging device.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Imaging Diagnostic Systems, Inc., (IMDS) announced that its CT Laser Mammography system (CTLM) has received Chinese State Food and Drug Administration (SFDA) marketing approval. Following extensive...

Exercise boosts recovery from cancer.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Women should aim for 1/2 hour of gentle exercise three times a week to aid their recovery from breast cancer, according to early results presented October 7, 2004, at a University of Bristol conference...

Fertility concerns affect treatment decisions of many young women with cancer.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Concern about infertility resulting from breast cancer therapy influenced treatment decisions in nearly one-third of young patients participating in a recent study. The study - the largest to date...

Genetic tumor virulence markers identified in murine model.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Genetic markers of tumor virulence have been identified in a murine model of breast cancer. "FVB/N-Tg (MMTV-PyMT)[superscript]634Mul-transgenic mice develop multifocal mammary tumors with a high...

Georgia medical center displays largest pink ribbon for breast cancer awareness.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- The typical fall colors at Southern Regional Medical Center (SRMC) will be infused with a hue more commonly associated with spring: pink. A 30-foot-long, 5-foot-wide banner of pink ribbon hangs on...

Grant enables study on cancer screening promotion.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- For one University of Georgia professor, research means the most fundamental of all differences: the difference between life and death. Three years ago Jeffrey K. Springston, associate professor in...

Healthy women need better understanding of disease incidence, risk factors.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Results of a study in Germany suggest healthy women need a better understanding of breast cancer incidence and risk factors. According to U.G. Pohls and colleagues, "The efficacy of early breast...

In vitro, arachidonic acid release may mediate tamoxifen, raloxifene actions.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- According to a study from the United States, "Tamoxifen is being used successfully to treat breast cancer. However, tamoxifen also increases the risk of developing endometrial cancer in postmenopausal...

Komen Foundation names husband-wife team honorary co-chairs for San Diego race.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- The San Diego Affiliate of the Susan G. Komen Breast Cancer Foundation announced Laurinda Nikkel as the honorary survivor chair and her husband, Arne Knudsen, as the honorary co-survivor chair for the...

LifeShirt System measures cardiopulmonary parameters in breast cancer study.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Researchers at the Tom Baker Cancer Center and University of Calgary are using the LifeShirt System from VivoMetrics in combination with the Mindfulness Based Stress Reduction program (MBSR) to help...

Medical device company announces kit for accelerated partial breast irradiation.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Nucletron B.V. announced the release of OncoSystem Breast, a complete turnkey kit for accelerated partial breast irradiation (APBI). OncoSystem Breast is a compilation of Nucletron products and...

Medical technology company receives financing to introduce BreastScanIR.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Infrared Sciences Corporation (ISC) announced that it has completed a $1 million series A preferred stock financing, acquiring the capital necessary to introduce BreastScan IR to a broader market of...

NYU Medical Center begins validation study on early detection breast cancer test.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Power3 Medical Products, Inc. (OTCBB: PWRM) announced institutional review board (IRB) approval from New York University Medical Center to begin the clinical validation studies on the company's NAF Test...

PC cell-derived growth factor inflames breast tumor aggression.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- PC cell-derived growth factor inflames breast tumor aggression. According to recent research published in the journal Carcinogenesis, "metastasis is a multi-step process involved in the progression...

Plus-size retailer raises funds to fight breast cancer.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Catherines, a leading plus-size retailer with more than 450 stores nationwide, is proud to introduce a Breast Cancer Awareness pin to help raise money towards the fight against breast cancer. The...

Soy isoflavones in food, rather than pure form, better for ER-dependent disease.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Soy isoflavones in food, i.e., soy flour-containing foods, rather than isoflavones in pure form are better for women with estrogen-dependent breast cancer, recommend nutritionists at the University of...

Specific vitamin D receptor gene polymorphisms associated with higher risk.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Researchers in the U.K. have identified specific vitamin D receptor gene polymorphisms that appear to be associated with breast cancer risk. "The steroid hormone 1,25-dihydroxyvitamin D is thought...

Study links low HDL levels with increased risk of postmenopausal breast cancer.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- The 2004 update from the American Heart Association's (AHA) Heart Disease and Stroke Statistics, coupled with a recently published study, documents that more than 50 million American women have...

Study shows chubby babies, lean adolescents have higher breast cancer rates.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- The way a girl grows during adolescence and even in the womb may play an important, if murky, role in her risk of breast cancer later in life, a Danish study suggests. The study of 117,000 women in...

Support groups aid women with BRCA1/2 gene mutations.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- A new study finds support groups can relieve the anxiety and depression associated with carrying BRCA1 or 2 gene mutations, the so-called "cancer genes." The results of the first study to...

The adenoviral type 5 E1A gene sensitizes breast tumors to paclitaxel.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- The adenoviral type 5 E1A gene sensitizes breast tumors to paclitaxel. "Paclitaxel (Taxol) is a promising frontline chemotherapeutic agent for the treatment of human breast and ovarian cancers. The...

Well-differentiated breast tumors have more 16q loss than poorly differentiated.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Well-differentiated breast tumors have more 16q loss than poorly differentiated tumors. According to a study from the Netherlands, "Loss of heterozygosity (LOH) at the long arm of chromosome 16 is a...

Write-on T-shirt becomes diagnostic tool in fight against breast cancer.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- The fight against breast cancer has a new weapon: powerful, yet as easy to use as slipping on a T-shirt. The Mark for Life breast self-exam kit includes a unique form-fitting T-shirt with printed...

Young breast cancer patients concerned with therapy's effect on fertility.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- A new study shows that concern about infertility resulting from breast cancer therapy influenced treatment decisions in nearly one third of young patients. The study, which appears in the Journal of...

Healthcare company encouraged by NCI silicone gel-filled breast implants study.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- INAMED Corporation (IMDC) reported that they are encouraged by results published in the October 1, 2004, issue of the American Journal of Epidemiology in which researchers at the U.S. National Cancer...

U.S. biotech invests in Australian cancer-focused company to widen collaboration.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- New York based biotechnology company Bioaccelerate, Inc. will invest in Australian Cancer Technology (ACU) by taking a $1.88 million share placement in the company. Included in the agreement is a...

Biotech firm strengthens drug pipeline by acquiring a phase II compound.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Biofrontera AG announced that it has acquired from ASAT AG, Zug, Switzerland, all intellectual property, know-how and material related to a phase II compound for the treatment of various cancerous and...

Cancer research foundation announces new partnership.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- The Lance Armstrong Foundation (LAF) has announced a 5-year, $500,000 gift to the Nevada Cancer Institute (NVCI) to establish the Lance Armstrong Foundation Survivorship Center at the Institute. The new...

Company changes name and prepares for HIV vaccine trial.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Research company Merix Bioscience announced the change of its name to Argos Therapeutics, Inc. Additionally, the company stated that it is preparing for an HIV clinical trial with Argos' proprietary...

Contract research organization opens office in top German biotech region.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- INC Research has opened an office in Germany, in Dusseldorf's Life Science Center. INC Research strategically located its facility in the North Rhine-Westphalia region of Germany, to be in close...

Partnership formed to market phase 3 chemoprotective agent in North America.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Takeda Pharmaceutical Company Limited has entered into an alliance agreement with U.S. based BioNumerik Pharmaceuticals, Inc., to market Tavocept (dimesna), a phase 3 chemoprotective agent developed by...

Pharma company and IVAX conclude license agreement for anticancer agent.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Nippon Shinyaku Co., Ltd., and IVAX Corporation concluded a license agreement for a novel anticancer agent, HMN-214. Under the agreement, Nippon Shinyaku has granted IVAX an exclusive license in...

Researchers gain insight into mechanism of cancer wasting.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- The often-fatal muscle wasting that accompanies many types of cancer is not simply a loss of muscle proteins generally, but seems to occur through a selective loss of particular muscle proteins,...

American Indian summit aims to raise cancer awareness.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Health statistics show that once diagnosed with cancer, American Indians have a lower 4-year survival rate than any other group in the country. Organizers of the Northern Plains American Indian...

Pharmacological unmasking microarray identifies tumor suppressor genes.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- A novel microarray analysis technique facilitates the identification of tumor suppressor genes. "Aberrant promoter hypermethylation of tumor suppressor genes is proposed to be a common feature of...

Changes made to computed radiography system.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- At the recent American Society for Therapeutic Radiology and Oncology meeting, Eastman Kodak Company announced changes to its computed radiography system, called KODAK 2000RT CR Plus. The company...

Columbus woman with cancer holds her own wake.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- On a recent Columbus, Ohio, Sunday so spectacular one could almost dismiss death as a distant and indistinct rumor, Kaye Manring welcomed the friends and kin attending her wake with an invitation to sip...

Biopharma company announces update on trial of compound for advanced cancers.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- NeoPharm (Nasdaq:NEOL) announced that results from a phase I clinical trial of the company's NeoLipid compound LE-SN38 in patients with advanced cancers were presented at the 16th Symposium on Molecular...

Companies announce filing of MAA in Europe to inject anticancer drug for MDS.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- SuperGen, Inc. (SUPG) and MGI Pharma Inc. (MOGN), announced that a marketing authorization application (MAA) seeking approval of Dacogen (decitabine) for injection has been submitted to the European...

Icelandic technology fund to support collaborative cancer diagnostics project.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- The Technology Development Fund of Iceland has decided to support a project aiming for the development of a new technology for diagnosing cancer. The project is to be performed by scientists at...

Leukemia society awards two $5 million grants to develop anticancer therapies.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- The Leukemia & Lymphoma Society awarded two Specialized Center of Research (SCOR) grants, bringing funding for the program, the society's most synergistic research initiative, past $77 million in the 5...

New therapy may counteract Paclitaxel resistance in cancer cells.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- As part of the 16th International Meeting of EORTC-NCI-AACR, Indena presented a new line of research based on IDN 5390, a taxane derivative showing a good preclinical profile to counteract Paclitaxel...

Hepatitis B virus core promoter mutations prevail in liver cancer.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Hepatitis B virus core promoter mutations prevail in liver cancer. "The role of hepatitis B virus (HBV) genotypes, core promoter (CP) and precore mutants on hepatocellular carcinoma (HCC) is still...

DOD awards sole-source contract for the ThinPrep Pap Test.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Cytyc Corp. (CYTC) announced that it has won a sole-source contract from the United States Department of Defense (DOD) to provide the ThinPrep Pap Test as the platform for cervical cancer screening at...

Rates of advanced breast cancer lower in The Netherlands due to mammography.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Public health specialists in The Netherlands credit the country's breast cancer screening program with reducing incidence of advanced disease. "The effect of the implementation of the Dutch breast...

Pharmaceutical company enters licensing agreement to develop oral cancer drug.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- IVAX Corporation (IVX) has entered into a licensing agreement with Nippon Shinyaku to develop and market HMN-214, a polo-like kinase inhibitor that targets pancreatic, prostate, and a number of other...

Pharma company presented six studies at cancer therapy conference.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- PharmaMar presented data from six studies, four of which were from pharmacogenomics research projects at the EORTC-NCI-AACR International Conference on Molecular Targets and Cancer Therapeutics, held in...

Anticancer activity of Scutellaria barbata characterized.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- The anticancer effects of Scutellaria barbata extract have been characterized. S. barbata, "a traditional Chinese herbal medicine native to southern China, is widely used as an anti-inflammatory and...

Biliary excretion of imatinib mesylate and metabolite characterized.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- The biliary excretion of imatinib mesylate and its metabolite has been characterized. "Imatinib mesylate, licensed to treat chronic myelogenous leukemia and gastrointestinal stromal tumors, is...

Compounds with MDR1-enhanced anticancer activity identified.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Several novel anticancer compounds have demonstrated heightened activity in the presence of the MDR1 multidrug transporter. "For analysis of multidrug resistance, a major barrier to effective...

Data analysis confirms BrachySilTM is safe and effective at tumor regression.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Global nanotechnology company pSivida Limited (ASX: PSD) and Singapore General Hospital (SGH) are pleased to announce Interim data analysis from pSivida's phase IIA trial at SGH has confirmed...

Data released on two spectrum selective kinase inhibitors: XL647, XL999.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Exelixis, Inc., (EXEL) released data at the 16th annual meeting of the European Organization for the Research and Treatment of Cancer (EORTC) in Geneva, Switzerland for two of its receptor tyrosine...

Data supports value of prostate brachytherapy.
November 2, 2004... 2004 NOV 2 - (NewsRx.com & NewsRx.net) -- Recent data from a 12-year follow-up of more than 1,500 patients showed brachytherapy as a powerful treatment for prostate cancer. Dr. Louis Potters, medical director of the New York Prostate...