Cancer Weekly articles from November 2003

Cancer Weekly archives from November 2003

Researchers discover new genetic link to common colon cancer.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- A team of researchers from University Hospitals of Cleveland (UHC) and Case Western Reserve University have identified a specific location on a human chromosome that can be linked to familial cases of...

Fly genes provide model for understanding how cancer spreads.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Howard Hughes Medical Institute (HHMI) researchers have developed a method for using the fruit fly Drosophila as a model to understand the genes that drive the spread of cancer. The screening test is...

5-FU infusion plus CPT-11 is an active and safe regimen in advanced CRC.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- 5-FU infusion plus CPT-11 is an active and safe regimen in advanced colorectal cancer (CRC). "We carried out a single-center series with the combination of irinotecan (CPT-11) plus protracted...

Breast cancer classification, prognosis can be based on gene expression profiles.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Breast cancer classification, prognosis can be based on gene expression profiles. "Comprehensive gene expression patterns generated from cDNA microarrays were correlated with detailed...

Anticoagulants could target the angiogenic properties of blood factors.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Anticoagulants could target the angiogenic properties of blood factors. "In addition to its primary role in hemostasis and blood coagulation, thrombin is a potent mitogen capable of inducing...

Chronobiology will result in more active treatment schedules for many diseases.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Chronobiology will result in more active treatment schedules for many diseases. According to recent research published in the journal Pathologie Biologie, "The medical applications of chronobiology...

Heightened p16 and p15 methylation may indicate high HNSCC risk.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Heightened p16 and p15 methylation may be a risk factor for HNSCC development. "Epigenetic silencing of the p16 and p15 genes by promoter methylation are commonly observed in human epithelial...

Human MUC1 carcinoma antigen regulates intracellular oxidant levels.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Human MUC1 carcinoma antigen regulates intracellular oxidant levels. According to a study from the United States, "The DF3/MUC1 transmembrane oncoprotein is aberrantly overexpressed by most human...

Researchers find genetic link.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Some men may be more prone to prostate cancer because a variation in a specific gene makes them more susceptible to the harmful effects of cancer-causing agents, a new study shows. The results of...

Clinical and molecular aspects of adrenocortical tumorigenesis reviewed.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Clinical and molecular aspects of adrenocortical tumorigenesis is reviewed. "Adrenal masses are a common problem affecting 3-7% of the population. The majority turn out to be benign adrenocortical...

Erythropoietin treatment could worsen cancer prognosis.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Results of a European study cast doubt over the value of treating anemia with erythropoietin (epoetin beta) among patients who have cancer. Results of the study show that anemic patients fare better in...

Spectrum of components of angiosarcomas accounts for difficulty in tumor typing.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- A wide spectrum of cellular components of angiosarcomas accounts for the difficulty in establishing accurate tumor typing. According to recent research from France, "To characterize the cytological...

IL-17 alone may enhance osteosarcoma cell lysis by natural killer cells.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Osteosarcoma cells have receptors to IL-17; IL-17 alone may enhance lysis by NK cells, but with IFNgamma they resist NK more. "We investigated the effect of the proinflammatory cytokine interleukin...

Ligand-targeted liposomal anticancer drugs may be developed soon.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Ligand-targeted liposomal anticancer drugs may be developed soon. "Antibody or ligand-mediated targeting of liposomal anticancer drugs to antigens expressed selectively or over-expressed on tumor...

Luminescent imaging is a useful tool for evaluating anticancer drugs in vivo.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Luminescent imaging is a useful tool for evaluating anticancer drugs in vivo. "Human DU-145 prostate and MCF-7 breast tumor cell lines were stably transfected with plasmid pcDNA3.1-Luc expressing...

Researchers develop an anticancer agent of marine origin.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Researchers develop an anticancer agent of marine origin. According to recent research from Netherlands, "Yondelis (trabectedin, ET-743) is a novel antitumor agent derived from a marine source, the...

Virus delivered nitroreductase/CB1954 acts synergistically with 5-FU on cancer.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- The enzyme-prodrug combination nitroreductase/CB1954 creates cancer cell apoptosis by the caspase pathway, and acts synergistically with 5-fluorouracil. According to published research from England,...

Passive immunotherapy appears to be an effective way to treat melanoma.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Passive immunotherapy should soon be a recognized way of effectively treating melanoma. According to recent research published in the journal Bulletin du Cancer, "The protocols of tumor...

Ganoderma lucidum, a mushroom, may prevent cisplatin-induced nephrotoxicity.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Ganoderma lucidum, a mushroom, may prevent cisplatin-induced nephrotoxicity. According to recent research published in the journal Current Science, "Cisplatin (cisplatinum (II) diamine dichloride)...

Interferons alpha and beta act on p53; do have antitumor, antiviral activities.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Interferons alpha and beta collaborate with p53, effecting tumor suppression and antiviral effects; new types of interferon or better targeted delivery may be clinically effective. "In the recent...

CD8 + chronic lymphocytic leukemia had other markers, cytokines expressed.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- In atypical chronic lymphocytic leukemia cells expressing CD8, there are a series of other unique immune markers and cytokines expressed. According to a study from Mexico, "Atypical chronic...

Cytology is highly accurate in diagnosing Barrett-associated neoplasia.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Cytology is highly accurate in diagnosing Barrett-associated neoplasia. According to a study from the United States, "We studied 327 consecutive paired esophageal biopsies and brushing specimens...

Transoral CO[subscript]2 laser excision of laryngeal paraganglioma is effective.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Transoral CO[subscript]2 laser excision of laryngeal paraganglioma is effective. According to a study from Germany, "Paragangliomas are rare benign neoplasms arising from the neural crest-derived...

Scanning array-designed antisense oligonucleotides predict effective therapy.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Scanning array-designed antisense oligonucleotides predict effective therapy. According to a study from England, "scanning oligodeoxynucleotide (ODN) arrays appear promising in vitro tools for the...

Brachytherapy seed company receives European CE Mark.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- IsoAid, LLC, announced receipt of its European CE Mark. Through the German organization, DQS, the company has demonstrated that it has implemented and maintains a quality-management system, in...

Local minocycline and systemic BCNU combine to curb intracranial glioma.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Local minocycline and systemic BCNU combine to curb intracranial glioma. "Minocycline, a tetracycline derivative, has been shown to inhibit tumor angiogenesis through inhibitory effects on matrix...

An expanding multicellular tumor system exerts significant mechanical pressure.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- An expanding multicellular tumor system exerts significant mechanical pressure. "Rapid volumetric growth and extensive invasion into brain parenchyma are hallmarks of malignant neuroepithelial...

Abnormal methylation of tumor suppressor genes occurs in sporadic breast cancer.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Abnormal methylation of several tumor suppressor genes occurs in sporadic breast cancer. "Multiplex methylation-sensitive PCR was employed in studying the methylation of CpG islands in the RB1,...

Acetylated Sp3 is a transcriptional activator.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Acetylated Sp3 is a transcriptional activator. According to a study from the United States, "Sp3 transcription factor can either activate or repress target gene expression. "However, the...

Antioxidant vitamins could lower the breast cancer risk in Korean women.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Antioxidant vitamins could lower the breast cancer risk in Korean women. "To investigate association between breast cancer risk and nutrient intake in Korean women, a case-control study was carried...

Apoptosis assays could be used to detect selective toxicity of anticancer drugs.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Apoptosis assays could be used to detect selective toxicity of anticancer drugs. "The goal of our study was to determine whether an apoptosis assay used after short-term drug exposure could predict...

Association between oral contraceptive use, breast cancer may vary by histology.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Association between oral contraceptive use, risk of breast cancer may vary by histologic type. According to recent research published in the International Journal of Cancer, researchers "examined...

Circulating tumor DNA may not be accurate reflection of breast cancer status.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Circulating tumor DNA may not be a sufficiently accurate reflection of breast cancer clinical status or tumor activity. "We evaluated the potential utility of occult circulating tumor DNA as a...

Commentaries question benefit of early screening.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- A series of three commentaries in the October 15, 2003, issue of the Journal of the National Cancer Institute addresses the issue of whether premenopausal women are being accurately informed about the...

Endo180 is a link between uPA-uPAR and setting the internal cellular compass.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Endo180 is a link between uPA-uPAR and setting the internal cellular compass in breast cancer. "Urokinase-type plasminogen activator (uPA) and its receptor (uPAR) play an important role in cell...

Grant finances study of gold-assisted laser radiation.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- A biomedical engineer and director of laser research at the University of Arkansas for Medical Sciences is trying to find a safe and efficient way to target cancerous cells using flecks of gold that are...

Interactions between breast cancer, osteoblastic cells induce osteoclastogenesis.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Direct interactions between breast cancer and stromal or osteoblastic cells induce osteoclastogenesis through modulating RANKL expression. "Bone destruction is primarily mediated by osteoclastic...

Lower white blood cell counts in black women may limit treatment and survival.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Lower white blood cell counts in African American women with early-stage breast cancer can lead to delays in treatment when compared with Caucasian women with the same stage of disease, according to a...

MammaCare, OHSU Cancer Institute, launch breast-screening training program.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- MammaCare and The Oregon Health & Sciences University (OHSU) Cancer Institute will launch a new program for breast cancer screening, the Mammatech Corp. (MAMH) announced. The Oregon Health &...

Premature adoption of sentinel node biopsy as standard test is a concern.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- A new study suggests that surgeons are routinely performing an investigational procedure called sentinel node biopsy (SNB) on women with early-stage breast cancer and this may be affecting the accrual...

Study of novel anticancer agent gets boost from $3M grant.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Roswell Park Cancer Institute (RPCI) has been awarded a Clinical Translational Research Grant of $3,089,794 by the Breast Cancer Research Program of the U.S. Department of Defense for the study of a...

Chronotherapy network involving institutions with expertise is being developed.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Chronotherapy network involving institutions with expertise is being developed. According to a study from France, "The EORTC Chronotherapy Group (CTG) stemmed from the International Organization for...

Hormonal factors associate with the risk for Hodgkin disease in women.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Hormonal factors associate with the risk for Hodgkin disease in women. "Reproductive factors have been suggested to have an impact on the development of Hodgkin disease (HD) in women. In the San...

Peptides derived from VEGF receptor 2 diminish angiogenesis in lab tests.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Peptides derived from VEGF receptor 2 diminish angiogenesis in lab tests. According to published research from Europe, "vascular endothelial growth factor (VEGF) is a potent mitogen for endothelial...

Mortality from cancer, other causes among male airline cockpit crew reviewed.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Mortality from cancer and other causes among male airline cockpit crew in Europe is reviewed. According to recent research from Germany, "Airline pilots and flight engineers are exposed to ionizing...

Lifestyle factors blamed for majority of cancer deaths.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Two-thirds of cancer deaths in the United States could be prevented through lifestyle changes in diet, exercise, cancer screening, and especially tobacco use, American Cancer Society CEO John Seffrin...

Heavy alcohol consumption linked to colorectal cancer.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Stony Brook University (Stony Brook, New York) researchers report that people who drink at least nine glasses of alcoholic beverages made with distilled spirits per week for more than 10 years are much...

Antitumor agent has promising pharmacological profile.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Modern methods of "high-throughput screening" make it possible to search for new pharmaceuticals in giant - though sometimes quite randomly compiled - substance libraries. In contrast, an...

Biotech-based anticancer therapies becoming more prevalent.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- New figures released today by Pharmaprojects show that a quarter of all anti-cancer therapies in development are based on biotechnology. Pharmaprojects analyzed the number of biotechnology products...

Imatinib suppresses marrow cell monocyte/macrophage differentiation.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Imatinib suppresses marrow cell monocyte/macrophage differentiation. "The antileukemic tyrosine kinase inhibitor, imatinib, has been reported to inhibit specifically the growth of bcr-abl expressing...

Molecular test measures extent of remission, potential for relapse.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- An international consortium of researchers reported the first use of a sensitive molecular test to measure the precise extent of remission or the likelihood of relapse in cancer patients being treated...

Phase I trials with HDAC inhibitor initiated.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- TopoTarget has initiated a Phase I clinical study of PXD101, its histone deacetylase (HDAC) inhibitor, in patients with advanced cancers. The two-center trial is being carried out by investigators...

Antigen-specific immunotherapy and cancer vaccines reviewed.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Scientists have published a review of antigen-specific immunotherapy and cancer vaccines in a recent issue of the International Journal of Cancer. "The specific activation of the immune system to...

Clinical studies of vaccines targeting breast cancer reviewed.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Investigators have published a review of clinical studies of vaccines targeting breast cancer in a recent issue of the journal Clinical Cancer Research. "Many clinical studies have been undertaken...

Dendritic cell vaccine induces T-cell immunity in stage IV melanoma patients.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Single injection of CD34+ progenitor-derived dendritic cell vaccine can lead to induction of T-cell immunity in patients with stage IV melanoma. According to a study from the United States, "There...

Heat shock protein from a non-autologous tumor used as anti-tumor vaccine.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Heat shock protein derived from a non-autologous tumor can be used as an anti-tumor vaccine. According to published research from Ireland, "Antigenic cross-reactivity between certain tumors has...

Her-2/neu is potential vaccine target for acute lymphoblastic leukemias.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- The Her-2/neu antigen is a potential vaccine target for acute lymphoblastic leukemias. "Her-2/neu is a tumor-associated antigen that is expressed on several adenocarcinomas and correlates with poor...

Immunogene vaccine improves outcome after combination therapy for myeloma.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Immunogene vaccination improved the outcome after combination therapy for myeloma murine myeloma. According to a study from Canada, "Increasing evidence suggests a role for immunologic vaccination...

The CD36 receptor is a critical target for antiangiogenic therapy.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- The CD36 receptor is a critical target for antiangiogenic therapy. "Thrombospondin-1 (TSP-1) is a potent inhibitor of angiogenesis in vivo and of microvascular endothelial cell responses to...

In vitro method of culturing cells useful in carcinogenesis studies.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- An in vitro method of culturing cells is useful in carcinogenesis studies. According to a study from the United States, "Mouse mammary epithelial cell cultures previously described bring about...

Akt/mTOR pathway involved in EGF-induced cell transformation.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Akt/mTOR pathway is involved in EGF-induced cell transformation. According to a study from the United States, "Our previous study demonstrated that phosphatidylinositol 3-kinase (PI3K) is necessary...

HPV DNA testing has a role in predicting cervical intraepithelial lesions.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- HPV DNA testing has a role in predicting cervical intraepithelial lesions. According to recent research from the United States, "Human papillomavirus (HPV) is widely accepted as the primary agent...

Advanced genomic technologies used as focus of alliance.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Cenetron Diagnostics, Ltd., a leading provider of molecular diagnostic services, announced it has signed a 5-year strategic alliance agreement with Roche Diagnostics to establish itself as a Molecular...

African Americans benefit from screening colonoscopy.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Researchers at Howard University College of Medicine (Washington, DC) found a high prevalence of premalignant polyps among their asymptomatic, average-risk African American patients. This study...

Dairy foods can reduce risk of colon cancer.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Dairy foods can reduce risk of colon cancer. According to a study from Australia, "Dairy foods can provide significant sources of energy and protein, minerals and vitamins into the human diet. ...

New strategies needed in prevention of colitis-associated cancer.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- New strategies are needed in prevention of colitis-associated cancer. "Colorectal cancer (CRC) remains a feared and potentially life-threatening complication of both ulcerative colitis and Crohn's...

"Virtual" colonoscopy may miss colon polyps and cancer.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- A new study finds that "virtual" colonoscopy - which uses imaging technology rather than a colonoscopy to screen for polyps and other lesions - missed 27% of colorectal lesions, including precancerous...

Study supports usefulness of colonoscopy.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- A study reviewing historical colonoscopy results found no statistically significant differences in the rates of cancer or other abnormalities between women who had symptoms of colorectal cancer and...

Fecal immunochemical test improves colorectal cancer screening.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Enterix Inc. announced that its InSure Fecal Immunochemical Test (FIT) significantly improved patient participation in colorectal cancer screening compared with Hemoccult, a traditional guaiac fecal...

Incidence, prevalence of colorectal cancer in IBD reviewed.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- The incidence and prevalence of colorectal cancer in inflammatory bowel disease is reviewed. According to published research from Denmark, "Although colorectal cancer (CRC), complicating ulcerative...

Mesalazine treatment significantly reduces the risk of developing cancer.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Mesalazine treatment significantly reduces the risk of developing cancer. "The chemoprevention of colorectal cancer (CRC) with long-term sulfasalazine and 5-aminosalicyclic acid (5-ASA) treatment...

Modelization of 5-FU clearance correlates to treatment response, toxicities.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Modelization of 5-FU clearance, index correlates to treatment response, toxicities. "Drugs pharmacokinetic control is a usual practice in case of flat continuous infusions. It enables among others,...

Predictive factors of raltitrexed-induced hepatotoxicity evaluated.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Predictive factors of raltitrexed-induced hepatotoxicity are evaluated. According to published research from Italy, "Raltitrexed (Tomudex; TOM) hepatotoxicity is usually characterized by a transient...

Breast CT may be comparable to mammogram and ultrasonography.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Breast CT may be comparable to mammogram and ultrasonography. According to recent research from South Korea, "Although computed tomography (CT) is not the primary method of evaluating breast...

Nitric oxide-mediated protection of apoptosis is p53-dependent.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Nitric oxide-mediated protection of apoptosis is p53-dependent. "Ser-46 of p53 is phosphorylated in response to DNA-damage in vivo, and it plays a pivotal role for apoptotic signaling by p53 through...

Anti-infective ability of DC should be studied to apply to anticancer efforts.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Dendritic cell based anticancer immunotherapy research should encompass anti-infectious response research. "Dendritic cells (DC) are the most potent antigen-presenting cells (APC) that initiate T...

Paraneoplastic pemphigus can occur with hepatocellular carcinoma, too.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Paraneoplastic pemphigus can occur with hepatocellular carcinoma, too. According to a study from Austria, "Paraneoplastic pemphigus (PNP) is an autoimmune mucocutaneous blistering disease associated...

Noninvasive test to diagnose cancer receives FDA clearance.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- 3TP (Three Time Point) has recently received U.S. Food and Drug Administration (FDA) clearance for use in the detection of breast and prostate cancer, which will enable doctors to distinguish between...

Glycolytic enzyme plays key role in L-nucleoside analog efficacy.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- An enzyme crucial for the efficacy of L-nucleoside analogs has been identified. These drugs represent "a new class of clinically active antiviral and anticancer agents," scientists in the United...

Medical end-of-life decisions commonly shared between caregivers, patients.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Medical end-of-life decisions are commonly shared between the involved caregivers and the patients. According to a study from Netherlands, "Information about medical decision-making in the last...

Lymphoscintigraphy, intraoperative gamma-probe may be tools for SLN detection.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- Lymphoscintigraphy and intraoperative gamma-probe may be promising tools for detection of SLNs. According to a study from Italy, "Lymphatic mapping and sentinel lymph node (SLN) biopsy are becoming...

New data describe efficacy of Cialis in hard-to-treat prostatectomy patients.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- According to the new clinical data on Cialis (tadalafil), 62% of men who underwent bilateral nerve-sparing radical retropubic prostatectomy, a surgery for prostate cancer, reported improved erections...

From genome comparisons, researchers learn lessons about evolution and cancer.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- In 1905, American astronomer Percival Lowell predicted the existence of a new planet he called Planet X. Lowell proved that this new planet existed even though no one had been able to see it in the sky....

Cancer vaccine company completes UKP 17M financing.
November 4, 2003... 2003 NOV 4 - (NewsRx.com & NewsRx.net) -- BioVex, Ltd., announced the completion of a UKP 17 million (U.S. $28 million) private placement. The placement was led by Scottish Equity Partners (U.K.). Other new investors participating in the...