Cancer Weekly articles from November 1999

Cancer Weekly archives from November 1999

CDC Study Finds HRT Not Associated with Increased Cancer Risk.(Statistical Data Included)
November 1, 1999... 1999 NOV 1 - (NewsRx.com) -- Adding to the debate on the relative risk for breast cancer in postmenopausal women using hormone replacement therapy, U.S. government researchers reported they found no such association in a study they conducted...

Cancer Treatment May Cause Learning Problems in Children.(Statistical Data Included)
November 1, 1999... 1999 NOV 1 - (NewsRx.com) -- Children with leukemia who undergo a particular form of chemotherapy run the risk of learning problems later in life, new research suggests. The decline in learning abilities may not show up for years. ...

Two Dimensional Gene Screening: Accurate and Cheap.(Statistical Data Included)
November 1, 1999... 1999 NOV 1 - (NewsRx.com) Two dimensional gene screening, which combines multiplex polymerase chain reaction amplification and two dimensional electrophoresis, is an accurate and inexpensive method of detecting BRCA1 mutations. BRCA1 is...

Women Have Unrealistic Expectations of Breast Cancer Screening.(Statistical Data Included)
November 1, 1999... 1999 NOV 1 - (NewsRx.com) -- Women have unrealistic expectations of the accuracy of breast cancer screening, finds research published in the Journal of Epidemiology and Community Health. The research focused on a sample of 115 women,...

Influence of Psychological Response on Survival in Cancer.(Statistical Data Included)
November 1, 1999... 1999 NOV 1 - (NewsRx.com) -- A woman with breast cancer, who has a fighting spirit towards her disease, will not have an increased overall length of survival after all, according to an article in the October 16, 1999, issue of The Lancet. ...

The 17-1A Antigen May Be a Potential Immunotherapeutic Target.(Statistical Data Included)
November 1, 1999... 1999 NOV 1 - (NewsRx.com) -- "A murine monoclonal antibody against the 17-1A epithelial antigen has been shown to be a useful adjuvant therapy in colorectal cancer, researchers from England report. They even suggest that its clinical use...

Angiogenesis Not a Predictor of Disease Recurrence, Study Finds.(Statistical Data Included)
November 1, 1999... 1999 NOV 1 - (NewsRx.com) -- Researchers in Belgium investigated whether angiogenesis can predict the risk of recurrence of cervical intraepithelial neoplasia after treatment. Microvessel density was studied in 75 patients with grade 3...

Recombinant Human Erythropoietin with Chemotherapy Reduces Transfusion Needs.(Statistical Data Included)
November 1, 1999... 1999 NOV 1 - (NewsRx.com) -- Erythropoietin administered with chemotherapy helped to reduce transfusion requirements in cancer patients, according to findings of a Phase III trial. Anemia is known to develop during preoperative chemotherapy...

Herpes Lymphadenitis May Not Have Fulminant Course.(Statistical Data Included)
November 1, 1999... 1999 NOV 1 - (NewsRx.com) -- In some immunosuppressed leukemia patients, herpes lymphadenitis may not have a fulminant course, researchers from the United States indicated. Herpes simplex virus (HSV) infections range in severity from common...

New Advances in Colon Cancer Genetics.(Statistical Data Included)
November 1, 1999... 1999 NOV 1 - (NewsRx.com) -- An inherited genetic mutation appears to be connected with certain familial late onset colorectal cancer cases, according to findings published in the journal Cancer Research. "We have previously identified...

Gene Therapy by Tumor Transduction with HSV-tk and Ganciclovir.(Statistical Data Included)
November 1, 1999... 1999 NOV 1 - (NewsRx.com) -- While gene therapy is feasible and may be safe as an adjuvant to the surgical resection of recurrent glioblastoma multiforme, there is slight, if any, benefit, report researchers in Switzerland. N. Shand, of...

HLA-A2 Polyepitope Vaccine for Melanoma Immunotherapy.(Statistical Data Included)
November 1, 1999... 1999 NOV 1 - (NewsRx.com) -- "Epitope-based vaccination strategies designed to induce tumor-specific CDS CTL, are being widely considered for cancer immunotherapy," suggested researchers from Australia. "...we describe a recombinant...

Gene Therapy Trial First To Activate Entire Human Immune System Against Cancer.(Statistical Data Included)
November 1, 1999... 1999 NOV 1 - (NewsRx.com) -- Cancer researchers from Johns Hopkins, Baltimore, Maryland, reported the successful use of human gene therapy to activate the human immune system against metastatic prostate cancer. The achievement, believed to...

Drug Company-Backed Research Less Critical than Independent Studies.(Statistical Data Included)
November 1, 1999... 1999 NOV 1 - (NewsRx.com) -- Researchers have found that studies on the cost-effectiveness of drugs are far more likely to report favorable findings if they are sponsored by the drug companies themselves rather than independent groups. ...

Cancer Therapy Targeting Angiogenesis Reviewed at Conference.(Statistical Data Included)
November 1, 1999... 1999 NOV 1 - (NewsRx.com) Cancer therapies targeting the inhibition of angiogenesis are a promising approach, an Austrian researcher suggests. U. Tontsch-Grunt from Boehringer-Ingelheim, Austria, presented data about the correlation...

BCG Therapy for Bladder Cancer Can Cause PSA Elevation.(Statistical Data Included)
November 1, 1999... 1999 NOV 1 - (NewsRx.com) -- Intravesical Bacillus Calmette Guerin (BCG) instillation for bladder cancer can cause elevations in prostate specific antigen (PSA) levels in men. Dan Leibovici and colleagues from Assaf-Harofe Medical Center,...

Growth Factor Is Increased in Certain Breast Cancer Cell Lines.(Statistical Data Included)
November 1, 1999... 1999 NOV 1 - (NewsRx.com) -- The vascular endothelial growth factor-165 (VEGF[165]) mRNA level is considerably higher in some breast cancer cell lines, according to a report from Israel. Active angiogenesis is necessary for the progressive...

COX-2 Inhibitors Reduce Risk of Colon Cancer.(Statistical Data Included)
November 1, 1999... 1999 NOV 1 - (NewsRx.com) -- Data presented at the Annual Meeting of the American College of Gastroenterology (ACG) by researchers at M.D. Anderson Cancer Center in Houston, Texas, reveal that celecoxib - one of the class of non-steroidal...

Colonoscopy Costs Compare Favorably with Other Screening Tests.(Statistical Data Included)
November 1, 1999... 1999 NOV 1 - (NewsRx.com) -- Colonoscopy screening is a cost-effective strategy for preventing colorectal cancer and increasing life expectancy among average risk patients over age 50 in a managed care setting. This is according to...

Vesicular Stomatitis Virus Glycoprotein Enhances Gene Delivery.(Statistical Data Included)
November 1, 1999... 1999 NOV 1 - (NewsRx.com) -- The fusogenic activity of vesicular stomatitis virus glycoprotein (VSVG) in tumors enhances therapeutic gene delivery, research from Texas suggests. N. Kazemi-Eslahi and colleagues from Valentis, Inc., Texas,...

Retroviral Vectors Are Backbone of Cancer Vaccine.(Statistical Data Included)
November 1, 1999... 1999 NOV 1 - (NewsRx.com) A retroviral vector transduced with interleukin-6 (IL-6) has strong anticancer activity. Andrzej Mackiewicz and colleagues from the University School of Medical Sciences at Great Poland Cancer Center, Poland,...

Study Underscores Fears of Discrimination Over Genetic Testing.(Statistical Data Included)
November 1, 1999... 1999 NOV 1 - (NewsRx.com) -- Fear of genetic discrimination often keeps those concerned they may be at risk for developing hereditary cancer away from the genetic testing that can, in some cases, save their lives. Concerns about...

Interferon Successfully Treats Kaposi's Sarcoma.(Statistical Data Included)
November 1, 1999... 1999 NOV 1 - (NewsRx.com) -- A female who developed Kaposi's sarcoma (KS) as a manifestation of T qualitative immunodeficiency was successfully treated for the KS with interferon. E. Sioula and colleagues from the Evangelismos Hospital,...

Testing Respiratory Spray To Treat Lung Cancer.(Statistical Data Included)
November 1, 1999... 1999 NOV 1 - (NewsRx.com) -- In a few years' time, it may be possible to use a respiratory spray to treat lesions in the mucous membranes of smokers' lungs, which are a real hotbed of lung cancer. Researchers in the U.S. and France...

New Model Furthers Understanding of Bone Metastasis.(Statistical Data Included)
November 1, 1999... 1999 NOV 1 - (NewsRx.com) -- New model furthers understanding of the mechanisms underlying bone metastasis in human neuroblastoma. T. Michigami and colleagues from the Osaka Medical Center, Japan, created an in vivo model of neuroblastoma...

MEN1 Gene Mutations Associated with Parathyroid Tumors.(Statistical Data Included)
November 1, 1999... 1999 NOV 1 - (NewsRx.com) -- Mutations in the MEN1 gene are associated with refractory hyperparathyroidism of uremia. Y. Imanishi and colleagues from Japan, Italy, France, and the U.S. investigated MEN1 gene mutations in parathyroid tumors...

Risk Factors Evaluated in Patients with Stomach Neoplasms.(Statistical Data Included)
November 1, 1999... 1999 NOV 1 - (NewsRx.com) -- Researchers in Russia studied risk factors for postoperative complications in patients with stomach neoplasms to facilitate finding preventive measures. A.V. Levanov and colleagues from the Russian Medical State...

Bioluminescence Helps Researchers Monitor Therapy.(Statistical Data Included)
November 1, 1999... 1999 NOV 1 - (NewsRx.com) Bioluminescence helps researchers monitor the efficacy of both chemotherapy and immunotherapy treatment in an animal model. Thomas J. Sweeney and colleagues from the Stanford University School of Medicine,...

C.W. Henderson Publisher Among Internet's Top Five Sites for Key Health Topics.(Statistical Data Included)
November 1, 1999... 1999 NOV 1 - (NewsRx.com) -- For major health, medical, and biotechnology niches, C.W. Henderson Publisher's web site is rated one of the five best on the Internet. Based on rankings conducted in October 1999 by the top three search...

Studying Quality of Life of Women with Lung Cancer.(Statistical Data Included)
November 1, 1999... 1999 NOV 1 - (NewsRx.com) -- The University at Buffalo (UB) School of Nursing, New York, is one of five nursing schools conducting the first national, large-scale study of quality-of-life issues affecting women with lung cancer in the U.S. ...

Phase II Trial of Novel Melanoma Vaccines Initiated.(Statistical Data Included)
November 1, 1999... 1999 NOV 1 - (NewsRx.com) -- Therion Biologics Corporation, Cambridge, Massachusetts, announced that it has initiated a Phase II clinical trial in collaboration with the U.S. National Cancer Institute (NCI) to evaluate two novel therapeutic...

Gene Therapy Used as Possible Weapon Against Prostate Cancer.(Statistical Data Included)
November 1, 1999... 1999 NOV 1 - (NewsRx.com) -- The Cleveland Clinic has been selected as one of three U.S. medical institutions to participate in a clinical trial of an innovative form of gene therapy for prostate cancer. Patients are currently being recruited...

IL-4 Regulates Gene Expression in Hepatocellular Carcinoma.(Statistical Data Included)
November 8, 1999... 1999 NOV 8 - (NewsRx.com) Interleukin-4 (IL-4) regulates gene expression in human hepatocellular carcinoma (HCC) cell lines, a Taiwanese study confirms. C. Hu and colleagues from the Veterans General Hospital and National Yang-Ming...

Memory T Cells Are Recognized by CD4(+) or CD8(+) T Lymphocytes.(Statistical Data Included)
November 8, 1999... 1999 NOV 8 - (NewsRx.com) Memory T cells isolated from the peripheral blood of patients with cancer can be identified and isolated with sensitive effector cell readout assays. Wolfgang Herr and colleagues from the University of Pittsburgh,...

Camptothecin and Topotecan - Nontoxic Inhibitors.(Statistical Data Included)
November 8, 1999... 1999 NOV 8 - (NewsRx.com) -- Camptothecin and topotecan inhibited endothelial cell growth and were nontoxic, according to a recent report. M.K. Clements and colleagues performed a study to determine the inhibitory nature of sublethal doses...

Soluble VEGF Is Present in Blood Components.(Statistical Data Included)
November 8, 1999... 1999 NOV 8 - (NewsRx.com) -- by Cathy Clark, Senior Editor -- Soluble vascular endothelial growth factor is present in blood components, depending on the duration of storage. Blood transfusion may diminish survival following curative...

Immunization with an Anti-Idiotypic Monoclonal Antibody Studied.(Statistical Data Included)
November 8, 1999... 1999 NOV 8 - (NewsRx.com) -- Researchers from England reported on the use of the anti-idiotypic monoclonal antibody 105AD7 as an adjuvant therapy in early stage colorectal cancer. 105AD7 emulates the tumor-associated antigen 791Tgp72, which...

Polycations/Cationic Lipids Enhance Adenovirus Transduction.(Statistical Data Included)
November 8, 1999... 1999 NOV 8 - (NewsRx.com) -- Polycations and cationic lipids enhance adenovirus-mediated transduction and transgene expression in tumor cells, researchers from the United States reported. "Replication-deficient adenovirus vectors are...

EGFr Inhibitor May Play Role in Cancer Treatment.(Statistical Data Included)
November 8, 1999... 1999 NOV 8 - (NewsRx.com) -- The epidermal growth factor receptor inhibitor CP-358,744 may be of value in the treatment of certain cancers. Phosphorylation of tyrosine residues on the epidermal growth factor (EGF) receptor (EGFr) is an...

Researchers Uncover Gene Related to Acute Leukemia.(Statistical Data Included)
November 8, 1999... 1999 NOV 8 - (NewsRx.com) -- Vanderbilt-Ingram Cancer Center researchers have uncovered another clue in the mystery of how chromosomal translocations cause acute leukemias. The findings suggest new treatment possibilities for these cancers of...

Does Unknown Hepatitis Cause Liver Cancer in Alaskan Natives?(Statistical Data Included)
November 8, 1999... 1999 NOV 8 - (NewsRx.com) -- A provocative study from Alaska suggests that a previously unknown chronic liver ailment may be linked to non-A, non-B hepatocellular carcinoma. Chronic infection with hepatitis B or C viruses is a common...

TT Virus Linked to Liver Cancer in Japanese Study.(Statistical Data Included)
November 8, 1999... 1999 NOV 8 - (NewsRx.com) -- The newly discovered transfusion-transmitted virus appears to be associated with liver cancer risk, according to a report from Japan. Many patients with hepatocellular carcinoma are positive for hepatitis B...

Recombinant Vaccinia Virus Encoding GM-CSF Tackles Melanoma.(Statistical Data Included)
November 8, 1999... 1999 NOV 8 - (NewsRx.com) -- Intratumoral injections of escalating doses of a vaccinia virus carrying granulocyte macrophage-colony stimulating factor (GM-CSF) is safe and effective against cutaneous melanoma. "Seven immunocompetent,...

Genetic Abnormality May Predict Cancer Spread.(Statistical Data Included)
November 8, 1999... 1999 NOV 8 - (NewsRx.com) -- Nearly 20 percent of women treated for ovarian cancer develop other tumors beyond the abdomen. Until recently, researchers have focused on prolonged survival or treatment of the disease as causes of these...

Children's Cancer Centers Inadequately Address Future Fertility.(Statistical Data Included)
November 8, 1999... 1999 NOV 8 - (NewsRx.com) -- A recent study suggests that children's cancer centers do not adequately address future fertility issues of their patients, including potential gamete conservation. A. Glaser and colleagues from children's...

Dietary Lipids Promote Mammary Carcinogenesis in Rats.(Statistical Data Included)
November 8, 1999... 1999 NOV 8 - (NewsRx.com) -- Dietary n-6 polyunsaturated lipids promote mammary carcinogenesis in rats. Montserrat Solanas, of Bellaterra, Spain, and associates determined the effect of dietary n-6 polyunsaturated lipids on induced mammary...

Genetic Manipulation Offers Hope for Numerous Disorders.(Statistical Data Included)
November 8, 1999... 1999 NOV 8 - (NewsRx.com) -- Gene therapy, in all of its numerous forms, offers hope for the treatment of disorders ranging from genetic defects to cancer to infectious diseases, suggests a researcher from the Baylor College of Medicine. ...

MDR-1 Gene Transfer Protects Bone Marrow from Chemotherapy.(Statistical Data Included)
November 8, 1999... 1999 NOV 8 - (NewsRx.com) -- MDR-1 gene therapy partially protects bone marrow against the potential mutagenic effects of etoposide (VP16) chemotherapy exposure. S.D. Turner and colleagues from the Christie Hospital, England, developed an...

System Evaluates How Gene Therapy Works for Cancer Treatment.(Statistical Data Included)
November 8, 1999... 1999 NOV 8 - (NewsRx.com) -- A scientific team hopes to begin human testing sometime in the year 2000 on new procedures that could help measure how well gene therapy is working in the treatment of cancer patients. "Currently, you inject...

Immunotherapy Uses Fusion Protein To Shrink Tumors.(Statistical Data Included)
November 8, 1999... 1999 NOV 8 - (NewsRx.com) -- An anticancer immunotherapy protocol uses antibody-facilitated cell-mediated tumor destruction as its modus operandi. P.M. Sondel and colleagues from the University of Wisconsin Comprehensive Cancer Center...

Melanoma, Ovarian Cancer Vaccine Data Presented.(Statistical Data Included)
November 8, 1999... 1999 NOV 8 - (NewsRx.com) -- Avax Technologies, Inc. (Avax), Kansas City, Missouri, announced that David A. Berd, MD, inventor of the AC Vaccine technology and professor of medicine, Kimmel Cancer Center, Thomas Jefferson University,...

Hepatitis-Related Carcinoma Predicted To Impact U.S. Soon.(Statistical Data Included)
November 8, 1999... 1999 NOV 8 - (NewsRx.com) -- A study released for the first time at the American Association for the Study of Liver Diseases (AASLD) 1999 Annual Meeting in Dallas, Texas, November 5-9, 1999, suggests that the United States may soon be seeing an...

Drug Designed To Block Protein that Causes Chronic Myelogenous Leukemia.(Statistical Data Included)
November 8, 1999... 1999 NOV 8 - (NewsRx.com) -- The drug STI-571, now being tested in clinical trials, is lowering white blood cell counts and actually altering abnormal cell structure to attack a common form of adult leukemia. "Six or eight months ago, I...

High-Dose Interferon Therapy Well-Tolerated , But of Unknown Benefit for Melanoma.(Statistical Data Included)
November 8, 1999... 1999 NOV 8 - (NewsRx.com) -- M.C. Murray and colleagues from the Hospital Nacional 'Prof. Dr. Alejandro Posadas', Argentina, presented a case study of a pediatric high-risk melanoma patient who successfully underwent high-dose interferon...

Genetic Factors in Neuroblastoma Studied.(Statistical Data Included)
November 8, 1999... 1999 NOV 8 - (NewsRx.com) -- The introduction of N-myc cDNA by adenovirus vectors helped Japanese researchers uncover the relevance of this gene to the undifferentiated phenotypes of neuroblastoma cells. T. Hishiki and colleagues from the...

NASA Inspired Probe Improves Safety and Efficiency of Brain Surgery.(Statistical Data Included)
November 8, 1999... 1999 NOV 8 - (NewsRx.com) -- The U.S. National Aeronautics and Space Administration (NASA) is applying technology destined for the Space Program to applications in neurosurgery. The NASA Smart Probe, intended for eventual use in a surgical...

HBV and Cancer in Children Examined.(Statistical Data Included)
November 8, 1999... 1999 NOV 8 - (NewsRx.com) -- The impact of hepatitis B infection on children with cancer was the focus of two poster presentations given at a major pediatric oncology meeting in September. Children with cancer are at risk for hepatitis B...

Heterogeneity Important when Assessing Prostate Death Rate.(Statistical Data Included)
November 8, 1999... 1999 NOV 8 - (NewsRx.com) -- Evaluating heterogeneity among families with a history of prostate cancer may be useful in predicting mortality from the disease. Researchers from the U.S. Centers for Disease Control and Prevention (CDC) and...

Occult Rhabdomyosarcoma Cells Detected by RT-PCR.(Statistical Data Included)
November 8, 1999... 1999 NOV 8 - (NewsRx.com) -- Occult rhabdomyosarcoma cells can be detected in peripheral blood, bone marrow, and stem cell harvest by the use of reverse transcriptase-polymerase chain reaction (RT-PCR). S. Gallego and colleagues from...

Expert Says Medical Practice Should Be Confined to Areas with Solid Scientific Basis.(Statistical Data Included)
November 8, 1999... 1999 NOV 8 - (NewsRx.com) -- Journalists should refrain from reporting on medical research that is anecdotal, provides only interim results, or that makes use of poor controls, according to an expert on medical technology, considered by many as...

Three U.S. Patents on p16 Tumor Suppressor Gene Announced.(Statistical Data Included)
November 8, 1999... 1999 NOV 8 - (NewsRx.com) -- Mitotix, Inc., Cambridge, Massachusetts, announced that the U.S. Patent and Trademark Office has issued three broad patents covering the tumor suppressor gene p16, a gene that plays a major role in regulating the...

Study Evaluates Chemotherapy Combination for Advanced Cancer.(Statistical Data Included)
November 8, 1999... 1999 NOV 8 - (NewsRx.com) -- The Southwest Oncology Group (SWOG) announced the beginning of the first major Phase III clinical trial to compare the chemotherapy combination of docetaxel (Taxotere) and estramustine phosphate (Emcyt) to the...

ErbB-4 Receptor Plays Role in Cell Proliferation.(Statistical Data Included)
November 15, 1999... 1999 NOV 15 - (NewsRx.com) Ribozyme technology demonstrates that the ErbB-4 receptor plays a role in estrogen-receptor-positive breast cancer proliferation. ErbB-4 is a recently discovered member of the class I receptor tyrosine kinase...

One HIV Gene Kills All Tumors in Lab Tests.(Statistical Data Included)
November 15, 1999... 1999 NOV 15 - (NewsRx.com) -- The enemy of my enemy is my friend - even if he was once my enemy. HIV uses a genetic arsenal that researchers at the University of Rochester Medical Center are turning against another enemy: cancer. If...

Analgesic-Induced Pathology Linked to Cancer in the Renal Pelvis.(Statistical Data Included)
November 15, 1999... 1999 NOV 15 - (NewsRx.com) -- Phenacetin-containing analgesics are strongly associated with the presence and severity of renal papillary scarring, thereby indirectly causing renal pelvic tumors. "Because phenacetin consumption ceased in New...

Gene Delivery System Produces Murine Tumor Models.(Statistical Data Included)
November 15, 1999... 1999 NOV 15 - (NewsRx.com) -- Researchers from the United States have developed a flexible and specific gene delivery system for production of murine tumor models. "To develop models of human cancer we have expressed the avian retroviral...

Anti-Vascular Endothelial Growth Factor Receptor Inhibits Tumors.(Statistical Data Included)
November 15, 1999... 1999 NOV 15 - (NewsRx.com) -- by Cathy Clark, Senior Editor -- An anti-vascular endothelial growth factor receptor monoclonal antibody may have therapeutic application for the treatment of some tumors. Tumor angiogenesis is mediated by...

Vitamin A Compound May Offer Protection in Younger Women.(Statistical Data Included)
November 15, 1999... 1999 NOV 15 - (NewsRx.com) -- Research by an international team of Italian and American scientists could pave the way for a new drug to prevent breast and ovarian cancers. Led by investigator Umberto Veronesi, MD, a clinical trial of women...

Estrogen Replacement Therapy Reduces Risk of Colorectal Cancer.(Statistical Data Included)
November 15, 1999... 1999 NOV 15 - (NewsRx.com) -- Older women who use estrogen replacement therapy (ERT) have a substantially lower risk of getting colorectal cancer, according to a study published in the October 1999 issue of Diseases of the Colon & Rectum. ...

Cellular Immunity Activated by Interferon-(beta) Gene Transfer.(Statistical Data Included)
November 15, 1999... 1999 NOV 15 - (NewsRx.com) Intratumoral interferon-(beta) (INF-(beta)) gene transfer exhibits antitumor effects and stimulates cellular immunity in a murine model of intracerebral glioma. Research has shown that cationic liposomes...

Clinical Trial Evaluates IL-2 and (beta)-IFN in Lung Cancer.(Statistical Data Included)
November 15, 1999... 1999 NOV 15 - (NewsRx.com) -- Researchers from the United States conducted a randomized Phase II study of interleukin-2 (IL-2) with and without beta-interferon ((beta)-IFN) for patients with advanced non-small cell lung cancer. "IL-2 and...

Estrogen-Driven Gene Activates Human Pituitary Tumors.(Statistical Data Included)
November 15, 1999... 1999 NOV 15 - (NewsRx.com) -- Estrogen stimulates a newly discovered oncogene in the pituitary gland, setting the stage for cell proliferation, a team of Cedars-Sinai Medical Center researchers reported in the November 1, 1999, issue of Nature...

Focal Adhesion Kinase Is Overexpressed in Ovarian Carcinoma.(Statistical Data Included)
November 15, 1999... 1999 NOV 15 - (NewsRx.com) Focal adhesion kinase is overexpressed in ovarian carcinoma, and thus, may be a possible target for disruption of cancer progression. "Focal adhesion kinase (FAK) is a cytoplasmic tyrosine kinase that is part of...

Soy Substances Slow Prostate Cancer Growth in Animals.(Statistical Data Included)
November 15, 1999... 1999 NOV 15 - (NewsRx.com) -- Substances present in dietary soy products may slow the growth of prostate cancer, an animal study has shown. But cancer researchers warn against rushing to use them as diet supplements. The finding suggests...

Research Challenges Conventional Thinking.(Statistical Data Included)
November 15, 1999... 1999 NOV 15 - (NewsRx.com) -- Research conducted by Memorial Sloan-Kettering Cancer Center, USA, investigators sheds new light on why existing therapies don't stop prostate cancer from returning. For decades, physicians have known that male...

Functional CD32 Molecules Found on Human Natural Killer Cells.(Statistical Data Included)
November 15, 1999... 1999 NOV 15 - (NewsRx.com) -- According to a study from the United States, the presence of a functional Fc gamma RII on the surface of natural killer (NK) cells could have important clinical consequences in tumor immunotherapy. "Human NK...

Interleukin-2 Can Be Safely Administered to Leukemia Patients.(Statistical Data Included)
November 15, 1999... 1999 NOV 15 - (NewsRx.com) -- Interleukin-2 (IL-2) may be safely administered to amyloid leukemia (AML) patients in their first remission. D. Skoric and colleagues from the University Children's Hospital, Yugoslavia, employed IL-2 therapy...

Phytoestrogens May Not Protect Women from Breast Cancer.(Statistical Data Included)
November 15, 1999... 1999 NOV 15 - (NewsRx.com) -- A protective effect of phytoestrogens against breast cancer was not confirmed in a recent study. I. den Tonkelaar, of the Julius Center for Patient-Oriented Research Medical Center, The Netherlands, and...

Tamoxifen Mechanism of Action Elucidated.(Statistical Data Included)
November 15, 1999... 1999 NOV 15 - (NewsRx.com) -- Tamoxifen, an estrogen antagonist used against breast cancer, has an inhibitory effect on insulin-like growth factor-1 (IGF-1). S.M. Corsello, of the Catholic University School of Medicine in Italy, and...

Gender Influences Chemotherapy Drug in Cancer Patients.(Statistical Data Included)
November 15, 1999... 1999 NOV 15 - (NewsRx.com) -- The sex of a cancer patient determines the disposition of the chemotherapeutic drug irinotecan, researchers from Illinois determined. C.E. Klein and colleagues from the University of Illinois and the...

Reversal of Tumor-Induced Immunosuppression Beneficial.(Statistical Data Included)
November 15, 1999... 1999 NOV 15 - (NewsRx.com) -- The reversal of tumor-induced immunosuppression is a beneficial adjunct to glioma immunotherapy, suggest researchers from Colorado. Y. Liu and colleagues from the University of Colorado Health Sciences Center...

Angiogenesis Measurement Is Predictive Factor in Radio-Chemotherapy.(Statistical Data Included)
November 15, 1999... 1999 NOV 15 - (NewsRx.com) -- Angiogenesis measurement may be useful as a predictive factor in radio-chemotherapy treatment in head and neck cancer. E. Dobrowsky of Austria's University of Vienna and colleagues performed...

Adjuvant Therapy Well Tolerated in Pediatric Melanoma Patient.(Statistical Data Included)
November 15, 1999... 1999 NOV 15 - (NewsRx.com) -- Adjuvant immunotherapy with interferon alfa 2b (IFN(alpha)2b) was well tolerated in a pediatric melanoma patient. W. Pietras and D. Wojcik from the Medical Academy, Poland, reported the case of a...

Study Examines Vessel Remodeling in Inner Areas of Tumors.(Statistical Data Included)
November 15, 1999... 1999 NOV 15 - (NewsRx.com) -- Angiogenic and angio-preserving tumor abilities may be controlled by different vasculature-related factors, according to a recent report. Neoangiogenesis during neoplastic growth involves endothelial mitogenic...