Cancer Weekly articles from November 1992

Cancer Weekly archives from November 1992

Institute defends exposing women to drug tamoxifen. (U.S. National Cancer Institute)
November 2, 1992... U.S. NCI The U.S. National Cancer Institute (NCI) defended exposing thousands of healthy women to the drug tamoxifen, saying risks of causing blood clots and some cancers are outweighed by the possibility it could prevent breast cancer....

Low risk of mother-to-child transmission of HTLV-II in non-breast-fed infants. (human T-lymphotropic virus type II) (32nd Interscience Conference on Antimicrobial Agents and Chemotherapy)
November 2, 1992... ICAAC Scientists have reported that human T-lymphotropic virus type II (HTLV-II) is rarely transmitted from mother to child in the absence of breast-feeding. In a study conducted by Drs. Jonathan Kaplan, Nathan Shaffer, Russell...

Molecule a key in cancer, evolution. (DNA polymerase beta) (University of Texas Medical Branch)
November 2, 1992... Texas One piece in a stubborn puzzle of both cancer and evolution - how spontaneous changes occur in DNA - has been solved, according to a team of scientists at the University of Texas Medical Branch at Galveston (UTMB) and the U.S....

Screening test may reduce cancer deaths according to researcher. (sigmoidoscopy; Dr. Polly A. Newcomb) (University of Wisconsin Comprehensive Cancer Center)
November 2, 1992... Wisconsin The risk of dying from colorectal cancer, the second most common cause of cancer death in the U.S., may be significantly reduced through wider use of a screening test that detects cancerous and pre-cancerous growths earlier...

Americans urged to seek screening for colorectal cancer. (Glaxo Institute for Digestive Health)
November 2, 1992... Glaxo Institute for Digestive Health A nationwide health education campaign to increase the number of Americans undergoing screening for colorectal cancer and thereby lessen the fatal impact of the disease on the nation was unveiled by...

Pregnancy estrogen level may be indicator of cancer risk. (Harvard University)
November 2, 1992... Harvard University The level of estrogen in a mother's system during pregnancy may have a bearing on her daughter's risk of breast cancer later in life, according to a new study. Reporting in the October 24, 1992, issue of the...

Low-fat, high-fiber diet no protection against breast cancer study disputed by doctors. (Illinois)
November 2, 1992... Illinois Some doctors disputed a surprising new study that found that eating less fat and more fiber offers no protection against breast cancer (see Cancer Weekly, October 26, 1992, pages 6-7). Two physicians said the study in the...

Agreement reached on breast-conserving treatment. (American Cancer Society)
November 2, 1992... American Cancer Society For the first time, three major health organizations whose members are directly involved in the care of breast cancer patients have agreed on which patients could be offered breast-conservation treatment. The...

Elderly and black women most at risk for breast cancer. (Florida)
November 2, 1992... Florida Elderly and black women are most at risk for breast cancer, according to an American Cancer Society report. More than half of all breast cancer occurs in women over 65, a study found. Black women, who are developing breast...

Group moves to categorize tobacco as an addictive substance to be regulated by FDA. (American Dental Association)
November 2, 1992... American Dental Association During the meeting of its main policy-making body, the House of Delegates, the American Dental Association (ADA) called for tobacco to be defined as an addictive drug regulated by the U.S. Food and Drug...

Study shows link between pet birds and lung cancer. (University of North Carolina)
November 2, 1992... University of North Carolina A lung cancer study has found that the disease isn't always linked to radiation, chemicals and smoking, says a North Carolina researcher. "One usually thinks that we can explain all excess lung cancers...

Colorado center funded to study lung cancer. (Colorado Cancer Center) (U.S. National Cancer Institute)
November 2, 1992... U.S. NCI The U.S. National Cancer Institute (NCI) has awarded Colorado Cancer Center in Denver a $5.5 million, three-year grant to study ways to detect lung cancer at earlier, more curable stages. The grant is expected to fund a...

Waiters, waitresses at risk from passive smoking, researcher says. (Dr. Michael Siegel) (California)
November 2, 1992... California Waiters and waitresses toiling away in smoky restaurants are at risk from the secondhand tobacco fumes they inhale, a university researcher said. "Previously, this has been looked upon as an issue of mainly comfort and,...

First "US TOO" prostate cancer support group in New York City announced. (American Foundation for Urologic Disease)
November 2, 1992... American Foundation for Urologic Disease Responding to the overwhelming need among patients with prostate cancer and their families for emotional and psychological assistance, the American Foundation for Urologic Disease (A.F.U.D.) and US...

Start of human clinical trials for new anti-tumor agent announced. (AG-337) (Agouron Pharmaceuticals Inc.)
November 2, 1992... Agouron Pharmaceuticals Agouron Pharmaceuticals Inc. announced that a clinical study of its anti-tumor agent designated AG-337 has been initiated at a major British medical center. The Phase I study of the Agouron drug is being...

Company, university agree to research and commercialize new cancer genes. (Oncor Inc./Johns Hopkins)
November 2, 1992... Oncor Inc./Johns Hopkins Oncor Inc., Gaithersburg, Maryland, and the Johns Hopkins University School of Medicine, Baltimore, Maryland, announced a joint collaborative research agreement for the discovery and commercialization of new...

Mallinckrodt Medical unit submits new drug application for cancer imaging agent. (IMCERA Group Inc.) (U.S. Food and Drug Administration)
November 2, 1992... U.S. FDA IMCERA Group Inc. announced that its Mallinckrodt Medical unit of St. Louis, Missouri, has submitted a New Drug Application to the U.S. Food and Drug Administration (FDA) for an imaging agent developed for the early diagnosis of...

Chesapeake health officials examine cancer death rate puzzle. (Maryland)
November 2, 1992... Maryland Just as health officials in the Chesapeake Bay region have begun to understand why the area has the nation's highest cancer death rates, they've run into other, perhaps even more perplexing problems. How do you convince an...

Hospital unveils effort to improve breast cancer treatment. (Massachusetts General Hospital, Boston)
November 2, 1992... Massachusetts Officials of Massachusetts General Hospital, Boston, say they will expand their fight against breast cancer by establishing a comprehensive center to coordinate treatment. The Comprehensive Breast Health Center, to...

The regulation, function and specificity of proteins induced in mammalian cells exposed to ionizing radiation. (National Cancer Institute research grant announcement) (Research Report)
November 2, 1992... AUTHORS: RFA Available: CA-93-02. National Cancer Institute. "Letter of Intent Receipt Date: December 10, 1992. Application Receipt Date: February 10, 1993. Purpose: The Division of Cancer Etiology of the National Cancer Institute...

Monoclonal antibody TJ4C4 as a marker for breast neoplasms. (Research Report)
November 2, 1992... AUTHORS: R.S. Cajulis, R. Hayden, D.F. Hidvegi, R.B. Duda, C.Z. August and J.A. Radosevich. Northwestern University, Chicago, Illinois, and Harvard University, Boston, Massachusetts. According to the authors' abstract of a poster...

Human fetal expression of the protein kinase (p68) using the monoclonal antibody TJ4C4. (Research Report)
November 2, 1992... AUTHORS: G.K. Haines, G. Ghadge and J.A. Radosevich. Northwestern University/V.A. Medical Center, Chicago, Illinois. According to the authors' abstract of a poster presentation to the annual meeting of the Midwest section of the American...

Phosphotyrosine expression in breast cancer specimens: relationship to c-neu and mortality. (Research Report)
November 2, 1992... AUTHORS: E.E. Lower and L. Williams. University of Cincinnati, Cincinnati, Ohio. According to the authors' abstract of a poster presentation to the annual meeting of the Midwest section of the American Federation for Clinical Research,...

In vivo evidence that a modified form of human c-reactive protein is an effective agent which suppresses the growth rate of mouse mammary cell line EMT6 murine breast cancer. (Research Report)
November 2, 1992... AUTHORS: J.J. Kresl, N.A. Meyer, L.A. Potempa, C.W. Chi, B. Anderson and J.A. Radosevich. Immtech International Inc., Evanston, Illinois, and Northwestern University, Chicago, Illinois. According to the authors' abstract of a poster...

Raynaud's phenomenon in three patients with AIDS-related Kaposi's sarcoma treated with bleomycin. (Research Report)
November 2, 1992... AUTHORS: C.F. von Gunten and J.H. Von Roenn. Northwestern University, Chicago, Illinois. According to the authors' abstract of a poster presentation to the annual meeting of the Midwest section of the American Federation for Clinical...

Thrombin stimulates the expression of urokinase-type plasminogen activator (uPA) from human prostate cancer cells. (Research Report )
November 2, 1992... AUTHORS: E. Yoshida, H.C. Kwaan, E.N. Verrusio and D. Oh. Northwestern University of the V.A. Lakeside Hospital, Chicago, Illinois. According to the authors' abstract of a poster presentation to the annual meeting of the Midwest section...

Response of fluconazole-treated cancer patients (pts) with candidemia compared with that of patients treated with amphotericin (AmB): a prospective matched pairs study. (Research Report)
November 2, 1992... AUTHORS: E. Anaissie, H. Pinczowski, L. Elting, D. Kontoyiannis, S. Vartivarian and G.P. Bodey. M.D. Anderson Cancer Center, Houston, Texas. According to the authors' abstract of a presentation to the 32nd Interscience Conference on...

Aerosolized pentamidine (AP) for the prevention of Pneumocystis carinii pneumonia (PCP) in children with cancer intolerant or allergic to trimethoprim/sulfamethoxazole (TMP/SMX). (Research Report)
November 2, 1992... AUTHORS: M.M. Mustafa, A. Pappo, N. Winick and G.R. Buchanan. University of Texas Southwestern Medical Center, Dallas, Texas. According to the authors' abstract of a presentation to the 32nd Interscience Conference on Antimicrobial...

Reduction in plasma or skin alpha-tocopherol concentration with long-term oral administration of beta-carotene in humans and mice. (Periodical Report)
November 2, 1992... SOURCE: Journal of the National Cancer Institute, October 21, 1992;84(20):1559-1565. Long-term oral administration of beta-carotene appears to decrease plasma concentrations of vitamin E, according to a report from the Arizona Cancer...

Continuous-infusion cisplatin, 5-fluorouracil and bolus methotrexate in the treatment of advanced non-small cell lung cancer. (Periodical Report)
November 2, 1992... SOURCE: Cancer, October 1, 1992;70(7):1880-1885. A continuous-infusion regimen containing cisplatin, 5-FU and methotrexate produced a good response rate in advanced non-small cell lung cancer (NSCLC) patients but resulted in a high...

Screening sigmoidoscopy and colorectal cancer mortality. (Periodical Report)
November 2, 1992... SOURCE: Journal of the National Cancer Institute, October 21, 1992;84(20):1572-1582. The risk of death from colorectal cancer appears to be significantly reduced in people who have at least one examination by screening sigmoidoscopy,...

Criteria for the definition of Epstein-Barr virus association in Hodgkin's disease. (Periodical Report)
November 2, 1992... SOURCE: Leukemia, September 1992;6(9):869-874. RNA in situ hybridization appears to be the most practical method of detecting Epstein-Barr Virus in tumor cells of Hodgkin's disease patients, according to a report from the University of...

Deferoxamine, cyclophosphamide, etoposide, carboplatin and thiotepa (D-CECaT): a new cytoreductive chelation-chemotherapy regimen in patients with advanced neuroblastoma. (Periodical Report)
November 2, 1992... SOURCE: American Journal of Clinical Oncology, 1992;15(4):319-322. A combination chemotherapy regimen involving the chelating agent deferoxamine given with cyclophosphamide, etoposide, carboplatin and thiotepa (D-CDCaT) appears to be an...

Early reports suggest no increase in childhood cancers from Chernobyl. (International Agency for Research on Cancer)
November 9, 1992... International Agency for Research on Cancer Early results of a childhood leukemia study in regions exposed to the 1986 radiation leak at the Chernobyl nuclear power plant show no increase risk due to the exposure. The preliminary...

Estrogen replacement therapy can raise risk of breast cancer. (Ohio State University)
November 9, 1992... Ohio State University Estrogen replacement therapy, a primary treatment for osteoporosis and symptoms of menopause, can double the risk of breast cancer in lean, post-menopausal women, a new study has shown. A similar increase in...

Breast implant records altered by employees. (Dow Corning)
November 9, 1992... Dow Corning A review of Dow Corning Corporation's silicone-gel breast implant business found some documents on manufacture of the implants in the 1980s had been altered, the company said November 2, 1992. The Midland, Michigan-based...

More women eligible for breast conservation, Boston cancer research team concludes. (American Society for Therapeutic Radiology and Oncology)
November 9, 1992... More cancer patients should be considered for breast-saving treatment, according to a study by a team of Boston researchers. Their study concludes that women with a small amount of cancer cells at the margins of a lumpectomy can still be...

Mastectomy indicated for some early stage breast cancers. (American Society for Therapeutic Radiology and Oncology)
November 9, 1992... Certain patients with early breast cancer should undergo mastectomy rather than breast-saving treatment, a new study confirms. Dr. Barbara Fowble, professor of radiation oncology at the Hospital of the University of Pennsylvania in...

Neutron beam therapy may increase survival in some prostate cancer patients. (American Society for Therapeutic Radiology and Oncology)
November 9, 1992... Men with locally advanced prostate cancer may be surviving longer after being treated with neutron beam therapy rather than conventional treatments, a preliminary study has found. Dr. Kurubarahalli Saroja, a radiation oncologist at...

Patterns of care study proves radiation therapy cures prostate cancer. (American Society for Therapeutic Radiology and Oncology)
November 9, 1992... Many men treated with radiation therapy for early stage prostate cancer live as long as their counterparts who have never had the disease, a first-of-its-kind study has found. Dr. Gerald Hanks, chairman of the Department of Radiation...

Colon cancer patients live longer when surgery supplemented with radiation. (American Society for Therapeutic Radiology and Oncology)
November 9, 1992... High-risk colon cancer patients are surviving longer when they are treated with surgery and radiation therapy rather than surgery alone, a Boston, Massachusetts study has found. Dr. Christopher G. Willett, radiation oncologist at...

Radiation therapy, surgery preserve normal body functions for rectal cancer patients. (American Society for Therapeutic Radiology and Oncology)
November 9, 1992... Using radiation therapy prior to surgery, doctors have been able to preserve normal bodily functions for many patients with cancer of the rectum. In the past, these patients would have been given a permanent colostomy. This medical...

Rapid new method reported to detect abnormal DNA associated with cancer. (Comparative Genomic Hybridization) (University of California, San Francisco)
November 9, 1992... A powerful new method for detecting gains or losses of portions of the genetic material DNA in abnormal cells promises to speed the discovery of genes that play a role in formation and spread of cancer. University of California, San...

Radiation exposure study will be very open, researcher says. (John Till, of Radiological Assessments Corp.; Savannah River Site) (U.S. Centers for Disease Control)
November 9, 1992... A researcher handling the contract for a study at the Savannah River Site (SRS) says he'll earn public credibility by being very open about information he gathers at the nuclear weapons plant. "Anything that I'm getting, you ought to be...

Some acute myeloid leukemias may be linked to occupational chemical exposure. (U.S. National Institute of Environmental Health Sciences)
November 9, 1992... Researchers have, for the first time, identified a link between job-related exposure to chemicals and development of acute myeloid leukemia in which a mutated cancer gene is present. The study, reported in the November 4, 1992, issue of the...

Eighth international cancer symposium held. (International Symposium on Cancer Research) (South Carolina)
November 9, 1992... Discussion of the bench-to-bedside or "translational" aspects of cancer research dominated the 8th International Symposium on Cancer Research, held in Charleston, South Carolina, in October 1992. The symposium was the annual meeting of...

Increased risk of cancer and heart disease for overweight teens. (Massachusetts)
November 9, 1992... Overweight teenagers are more likely than their thin friends to suffer such problems as heart disease, colon cancer, arthritis or gout by age 70, according to a study. Men who were fat adolescents begin to die at a higher-than-usual rate...

U.S. patent on the use of targeted cytotoxic agents for cancer therapy issued. (maytansinoids) (ImmunoGen Inc.)
November 9, 1992... ImmunoGen Inc. announced that the U.S. Patent and Trademark Office has issued a Notice of Allowance for the company's patent application on the use of a family of highly potent chemical agents called maytansinoids. The allowed patent...

Skin cancer trials of new drug begun. (benzoporphyrin derivative) (Canada)
November 9, 1992... Quadra Logic Technologies Inc. (QLT), Vancouver, British Columbia, announced that a clinical trial of the company's light-activated drug, Benzoporphyrin derivative (BPD), has commenced in Canada. The clinical trial, which is being...

Mycelex Troche given new prophylaxis indication for oral thrush in immunocompromised patients. (Miles Inc.)
November 9, 1992... The Pharmaceutical Division of Miles Inc., Pittsburgh, Pennsylvania, announced it received regulatory approval to market its Mycelex (clotrimazole) Troche medication for the prophylactic treatment of oral fungal infections in immunocompromised...

Zila's Orascan application advances. (oral cancer detection system) (U.S. Food and Drug Administration)
November 9, 1992... Zila Inc.'s President, Joseph Hines announced that "Zila has moved significantly closer to gaining approval from U.S. Food and Drug Administration (FDA) to market Orascan in the United States." Hines said the FDA informed Zila that the...

R&D and licensing agreements signed to develop drugs using synthetic peptide technology. (Thomas Jefferson University/Raggio-Italgene)
November 9, 1992... Thomas Jefferson University, as part of its strategy to bring molecular medicine from the laboratory bench to the patient bedside, has signed R&D and licensing agreements with Raggio-Italgene, a biotechnology company based in Pomezla, Italy,...

Oxigene files IND for novel formulation of metoclopramide. (Investigational New Drug application) (U.S. Food and Drug Administration)
November 9, 1992... Oxigene Inc., New York, New York, announced that it has filed an Investigational New Drug (IND) application with the U.S. Food and Drug Administration (FDA) for a novel formulation of the drug, metoclopramide, to enhance the efficacy of...

Interactive Research Project Grants for nutrition and cancer prevention. (National Cancer Institute research grant announcement) (Research Report)
November 9, 1992... AUTHORS: RFA Available: CA-93-04. National Cancer Institute, Division of Cancer Prevention and Control. "Letter of Intent Receipt Date: November 24, 1992. Application Receipt Date: January 19, 1993. Purpose: The Division of Cancer...

Improved outcome with postoperative radiation therapy in high risk colon cancer. (Research Report)
November 9, 1992... AUTHORS: Claire Y. Fung, Christopher G. Willett, Jim T. Efird and Paul C. Shellito. Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, Massachusetts. According to the authors' abstract of a presentation to the...

Breast-conserving surgery and definitive radiation: a comparison between quadrantectomy and local excision with special focus on cosmesis and local control. (Research Report)
November 9, 1992... AUTHORS: M.A. Fagundes, H.M. Fagundes, C.S. Brito, M.H. Fagundes, L.A. Bruno, S.J. Azevedo and L.A. Fagundes. University of Miami, Miami, Florida, and the Center for Oncological Radiotherapy, Porto Alegre, Brazil. According to the...

Erythropoietin increases in cancer patients during radiation therapy. (Research Report)
November 9, 1992... AUTHORS: Robert S. Lavey. University of California, Los Angles and Jonsson Comprehensive Cancer Center, Los Angeles, California. According to the author's abstract of a presentation to the 34th annual meeting of the American Society for...

Results of a policy of surveillance in stage I testicular seminoma. (Research Report)
November 9, 1992... AUTHORS: P. Warde, M. Gospodarowicz, J. Sturgeon, M. Jewett, C. Catton, G. Thomas, W. Duncan and A. Munro. The Princess Margaret Hospital, Toronto, Ontario, Canada. According to the authors' abstract of a presentation to the 34th...

Breast cancer in premenopausal women: is young age at diagnosis an independent prognostic factor? (Research Report)
November 9, 1992... AUTHORS: Anne de la Rochefordiere, Bernard Asselain, Francois Campana, J. Fenton, J.R. Vilcoq and Alain Fourquet. Institute Curie, Paris, France. According to the authors' abstract of a presentation to the 34th annual meeting of the...

Mutations of p53 gene in hepatocellular carcinoma: roles of hepatitis B virus and aflatoxin contamination in the diet. (Periodical Report)
November 9, 1992... SOURCE: Journal of the National Cancer Institute, November 4, 1992;84(21):1638-1641. A possible interaction of chronic hepatitis B virus (HBV) infection and p53 gene mutation indicates a mechanism by which HBV infection beginning early...

Insulin-like growth factor binding proteins in human breast cancer tissue. (Periodical Report)
November 9, 1992... SOURCE: Cancer Research, October 1, 1992;52:5204-5207. The increased content of insulin-like growth factor binding protein (IGFBP) is often associated with the malignant transformation of breast tissue, according to a report from the...

Effects of verapamil on the acute toxicity of doxorubicin in vivo. (Periodical Report)
November 9, 1992... SOURCE: Journal of the National Cancer Institute, November 4, 1992;84(21):1653-1660. Verapamil effectively inhibits doxorubicin-mediated lipid peroxidation in vivo, but cardiac lipid peroxidation is not the major limiting mechanism...

Effects of tamoxifen adjuvant therapy and a low-fat diet on serum binding proteins and estradiol bioavailability in postmenopausal breast cancer patients. (Periodical Report)
November 9, 1992... SOURCE: Cancer Research, October 1, 1992;52:5386-5390. In postmenopausal breast cancer patients the redistribution of circulating estradiol, with reduced bioavailability, provides an additional mechanism to those demonstrated previously...

A Phase III trial of mitomycin C alone versus mitomycin C, vinblastine and cisplatin for metastatic squamous cell lung carcinoma. (Periodical Report)
November 9, 1992... SOURCE: Cancer, November 1, 1992;70(9):2281-2287. Mitomycin C has antitumor activity against squamous cell lung carcinoma when used in combination with vinblastine and cisplatin, according to a report from the North Central Cancer...

Acute lymphoblastic leukemia in patients aged 60 years and over: a population-based study of incidence and outcome. (Periodical Report)
November 9, 1992... SOURCE: Blood, October, 1992;7(1):1813-1817. The prognosis for acute lymphoblastic leukemia (ALL) patients over the age of 60 is extremely poor, but age should not be a bar to curative treatment, according to a report from a British...

Radiation, chemotherapy produce high cure rates for young Hodgkin's disease patients. (American Society for Therapeutic Radiology and Oncology)
November 16, 1992... Children under 10 years of age have an excellent chance of being cured of Hodgkin's disease when treated with radiation therapy and chemotherapy. This is the conclusion of a team of research scientists who studied patients at Stanford...

Radiation therapy saves voice box for patients with larynx cancer. (American Society for Therapeutic Radiology and Oncology)
November 16, 1992... Many patients with recurrent cancer of the larynx can save their vocal cords if treated again with radiation therapy. In the past, it was believed that once the larynx had been exposed to radiation, additional radiation therapy was not...

3-D radiation therapy planning helps physicians locate lung cancers. (American Society for Therapeutic Radiology and Oncology)
November 16, 1992... Three-dimensional treatment planning is launching radiation therapy into the 21st century by allowing radiation oncologists to better pinpoint lung tumors in hopes of increased survival. According to Dr. M.V. Graham, instructor of...

School of Medicine launches program in gene therapy. (University of California, San Diego)
November 16, 1992... The University of California, San Diego, (UCSD) School of Medicine has formed a program in gene therapy to facilitate the transfer of basic science advances to clinical trials in humans, School of Medicine Dean John Alksne, M.D., announced....

Scientists report gene therapy successes in animal cancer models to treat cancer. (Viagene Inc.)
November 16, 1992... Scientists at Viagene Inc., San Diego, California, have reported encouraging results in animal models using gene therapy to treat cancer. The multi-study research was presented at the First International Conference on Gene Therapy of...

Genetically altered brain tumors mimic herpes virus. (U.S. National Cancer Institute)
November 16, 1992... Researchers at the U.S. National Cancer Institute (NCI) are using gene therapy to fool brain cancers into mimicking the herpes virus. The next step is to treat the tumor with a drug that wipes out herpes. "It worked in rats last...

Researchers intensify efforts to understand and treat childhood brain cancer. (University of California, San Francisco)
November 16, 1992... Better ways to save children with brain tumors may result from a novel research program to begin at the University of California, San Francisco (UCSF), with $950,000 awarded by the U.S. National Institutes of Health through a nationwide grant...

Long-term follow-up clinic for survivors of childhood cancer established. (Scottish Rite Children's Medical Center)
November 16, 1992... The Hematology/Oncology Center at Scottish Rite Children's Medical Center (SRCMC), Atlanta, Georgia, has established a Long-Term Follow-up Clinic for survivors of childhood cancer. The clinic will provide support to patients in remission...

Drug for prostate cancer to be tested. (suramin) (University of California, Los Angeles)
November 16, 1992... Suramin, an experimental drug that has shown encouraging preliminary results in thwarting advanced prostate cancer, is now being tested on a wider scale at the University of California at Los Angeles (UCLA) Clark Urology Center and Bowyer...

Prostate cancer prevention trial begins. (clinical trial of 4HPR) (Harper Hospital/Wayne State University, Detroit, Michigan)
November 16, 1992... Researchers at Harper Hospital/Wayne State University, Detroit, Michigan, have initiated a clinical trial using a vitamin A-like drug aimed at preventing prostate cancer in high-risk individuals. Kenneth Pienta, M.D., principal...

Budget includes $2 billion for cancer. (U.S. National Institutes of Health)
November 16, 1992... The 1993 budget for the U.S. National Institutes of Health (NIH), signed into law by President Bush in October 1992, includes $2.007 billion for the U.S. National Cancer Institute (NCI), an increase of $36 million, or 1.8 percent, over the...

Fred Hutchinson Cancer Center to receive $140 million for women's health. (U.S. National Institutes of Health)
November 16, 1992... The U.S. National Institutes of Health (NIH) has awarded a $140 million, 15-year contract to the Fred Hutchinson Cancer Research Center in Seattle, Washington, to launch the Women's Health Initiative. The initiative, devoted to research...

Pitt researcher among two honored for breast cancer therapy. (Dr. Bernard Fisher, University of Pittsburgh, and Dr. Gianni Bonadonna, Italian National Cancer Institute, receive Dr. Josef Steiner Cancer Research Prize) (Switzerland)
November 16, 1992... Two doctors from the United States and Italy will share a $300,000 award for their development of a widely used treatment for breast cancer, the Dr. Josef Steiner Cancer Foundation, Bern, Switzerland, announced. The award was given to...

Test-tube growth of taxol shows promise. (American Institute of Chemical Engineers)
November 16, 1992... The anticancer chemical Taxol found only in the bark of Pacific yew trees apparently can be grown economically in a test tube, a scientist announced. The drug has been used successfully to fight ovarian and breast cancer and shows...

Project to compare the incidence of cancer in counties near the Savannah River Nuclear Site initiated. (South Carolina)
November 16, 1992... The Medical University of South Carolina (MUSC) at Charleston is conducting a project to compare the incidence of cancer in counties near the Savannah River Nuclear Site with national norms. The Savannah River Region Health Information...

Steering committee approves draft report on cancer in Los Alamos. (New Mexico)
November 16, 1992... Three West Virginia counties will be the targets of a $1.7 million U.S. National Cancer Institute funded project to attack breast and cervical cancer in rural low-income women over 40. The research program will involve Calhoun, Wirt and...

Three counties plan cancer research project. (West Virginia)
November 16, 1992... Three West Virginia counties will be the targets of a $1.7 million U.S. National Cancer Institute funded project to attack breast and cervical cancer in rural low-income women over 40. The research program will involve Calhoun, Wirt and...

Cipollone tobacco lawsuit dropped, more than 60 lawsuits pending. (Rose Cipollone) (New Jersey)
November 16, 1992... The cigarette industry's legal troubles are far from over with the dismissal of a landmark liability case brought by a New Jersey lung-cancer victim nearly 10 years ago. More than 60 cigarette liability lawsuits are pending in courts...

Report criticizes American Cancer Society's Michigan division. (James Bennett report)
November 16, 1992... Less than one-third, or 32 cents of each dollar spent by the American Cancer Society's (ACS) Michigan division in Detroit, goes directly to patient care, according to an economist's report. Most money - 56 cents of each dollar - goes to...