Cancer Weekly articles from March 2004

Cancer Weekly archives from March 2004

More cancers have genetically caused types than previously thought.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Most cancers occur sporadically. At least 5.5% of cancer cases are based on a genetic predisposition. These are usually identified because first-degree relatives develop the same type of tumor. So...

Proteasome is target for cancer therapy.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- The proteasome is a target for cancer therapy. According to published research from the United States, "The proteasome is a multicatalytic proteinase complex responsible for the degradation of most...

Tumor cell-specific therapy shows preclinical promise.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Cancer often begins with mutations in tumor suppressor pathways. Tumor suppressor genes - such as p53 - arrest cell growth and induce apoptosis (programmed cell death) in response to cellular stress,...

New mathematical algorithms might help diagnose cancer.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Dartmouth researchers have developed an algorithm that might someday be used to analyze blood for diagnostic purposes. Using data from a mass spectrometer, a device that generates a molecular...

New way found to predict metastasis.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- A new way of predicting whether skin cancers will spread to other organs has been developed by British researchers. This means that resources can be concentrated on those patients most in need of close...

Protein cross-talk regulates mesothelial cancer cell proliferation.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Protein cross-talk regulates mesothelial cancer cell proliferation. According to a study from Italy, "vascular endothelial growth factor (VEGF) and semaphorin-3A (Sema-3A) play important roles in...

FDA approves Genasense NDA.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Genta, Inc., (GNTA) and Aventis (AVE) announced that the U.S. Food and Drug Administration (FDA) has accepted the new drug application (NDA) for Genasense (oblimersen sodium), the first systemic...

Betula platyphylla var. japonica extract may have anticancer properties.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Animal model shows that Betula platyphylla var. japonica has potential anticancer and antioxidant properties, researchers report. "The antioxidant and anticancer properties of a medicinal plant,...

Risk of basal cell carcinoma is increased by alcohol intake.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Basal cell carcinoma is associated with alcohol consumption but not with smoking, study finds. According to a study from the United States, "We prospectively investigated whether alcohol intake and...

Alkaline comet assay predicts bladder cancer cell radiosensitivity.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Bladder cancer cell radiosensitivity can be predicted using the alkaline comet assay (ACA), which can potentially identify nonresponsive tumors, researchers say. "In the UK, the two main treatments...

Alphastatin is a potent inhibitor of activated endothelial cells.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Alphastatin is a potent inhibitor of activated endothelial cells. According to recent research from England, "angiogenesis, the development of new blood vessels from existing vasculature, is crucial...

PA health department study shows 18% of 8th graders overweight.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Pennsylvania Health Secretary Dr. Calvin B. Johnson announced that 18% of the eighth graders who were studied in a recent assessment were overweight and another 17% are at risk of being overweight. ...

MRI and CT can be used to diagnose intracerebral hematoma.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- CT and MRI are useful in diagnosing intracerebral hematomas, but angiography may be needed to determine whether there is an intracranial vascular malformation. According to published research from...

Genetic patterns were stable in human malignant glioma xenografted in nude mice.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Studying subcutaneous xenografts in nude mice is promising for analysis of the molecular profile of malignant astrocytoma and oligodendroglioma, researchers report. "In order to develop preclinical...

A new assay detects MGB1 transcript in the blood of breast cancer patients.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Researchers develop a sensitive assay to detect mammaglobin (MGBI)in peripheral blood of breast cancer patients, which may have prognostic significance. According to researchers writing in the...

An informational video can improve breast cancer clinical trial knowledge.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Study shows that viewing an informational video about participation in clinical trials is beneficial in educating patients about potential participation in a trial. "A total of 262 women in the USA...

CHEK2*1100delC germline mutation carriers are at risk for another breast tumor.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Patients who are CHEK2* 1100delC mutation carriers should undergo prolonged surveillance because of increased risk of developing another breast tumor. According to recent research published in the...

Combo GET therapy well tolerated in metastatic breast cancer.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Clinical trial finds that the combination of gemcitabine, epirubicin and paclitaxel (GET) has acceptable toxicity and is active in patients with metastatic breast cancer. "In this phase II,...

FDA accepts NDA with priority review for RSR13.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Allos Therapeutics, Inc., (ALTH) announced that the Division of Oncology Drug Products at the U.S. Food and Drug Administration (FDA) has accepted for review the company's New Drug Application (NDA)...

Free estradiol and breast cancer risk can be calculated for use in studies.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Study results suggest that for epidemiological studies, it is only necessary to measure total estradiol (E2) concentration and sex hormone binding globulin (SHBG) concentration, with hormone fractions...

Full-field breast ultrasound complements mammography.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Siemens Medical Solutions Ultrasound Division and U-Systems, Inc., a developer of full field breast ultrasound (FFBU), have entered into an agreement where Siemens' provides the ultrasound engine of the...

Gabapentin reduces tamoxifen-induced hot flashes in women with breast cancer.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- A pilot study finds that gabapentin administration in women with breast cancer significantly improved tamoxifen-induced hot flashes. "In this pilot study, 22 women with breast cancer on tamoxifen...

Immune response to telomerase tumor antigen studied as possible vaccine.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Researchers at the Abramson Cancer Center of the University of Pennsylvania have begun a Phase I clinical trial to evaluate the effectiveness of a telomerase peptide as a possible vaccine against breast...

Mammography more stressful for survivors of disease.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- The stress of mammography after surviving breast cancer may cause health risks beyond having a history of the disease itself, a new study suggests. Breast cancer survivors find follow-up mammography...

Much breast cancer treatment in clinical practice does not follow guidelines.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Study finds that there is poor adherence to guidelines for breast cancer treatment in clinical practice. "There is sparse evidence on community practice patterns in treating women with breast...

Mutations, especially 11q loss, may be involved in early-onset breast tumors.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- The combined use of genomic patterns and molecular targets may provide a useful tool for diagnostic, therapeutic, and prognostic purposes in early-onset breast tumor development in Taiwanese women. ...

Paget carcinoma cells differ from those of the underlying carcinoma.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Study finds that the underlying tumors in the breast are coincidental neoplastic lesions (collision tumors) different from Paget carcinoma (PC) cells. "Paget's carcinoma of the breast is...

Sarcomas of the breast prone to relapse unless wide surgical margains attained.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Sarcomas are rare lesions in the breast and treatment should focus on surgical removal with wide margins. "Breast sarcomas are rare lesions that can be derived from any of the mammary stromal...

Spanish women with family history need education about breast cancer.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Spanish women need interventions to increase their adherence to breast cancer screening. According to recent research from Spain, "Women with a family history of breast cancer (FHBC) are at...

Two drinks a day increases risk of breast cancer, study shows.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- "Alcohol consumption is one of the best established risk factors for breast cancer development," says epidemiologist Joann Dorgan, PhD, of Fox Chase Cancer Center, Philadelphia, Pennsylvania. Dr....

Higher breast density is associated with increased breast cancer risk.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Determining breast density by mammography may be helpful in assessing breast cancer risk, researchers report. According to a study from the United States, "Increased mammographic breast density is...

New estrogen inhibitor in phase II development.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Ascend Therapeutics, Inc., announced that it has obtained exclusive North American development, marketing and commercialization rights to the developmental pharmaceutical product, TamoGel...

Cancer center lays off 89 employees amid insurance dispute.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- The Parker Hughes Cancer Center in Minneapolis, Minnesota, laid off 89 employees, and top officials at the Roseville clinic took drastic pay cuts just days after the nonprofit ended its contracts with...

Cialis maker reports results for 2003.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- ICOS Corp. (ICOS) summarized 2003 highlights, released its financial results for the year and fourth quarter ended December 31, 2003, and provided guidance regarding financial performance expectations...

Small molecule drug company files registration statement for IPO.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Metabasis Therapeutics, Inc., announced in February 2004 that it has filed a registration statement with the U.S. Securities and Exchange Commission relating to an initial public offering (IPO) of its...

Drug discovery company announces name change, new appointments.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Semafore Pharmaceuticals, Inc., announced the company's name change from ComChem Technologies to better reflect the company's strategic focus. Semafore's therapeutic programs are based on...

Pharmaceutical company announces dismissal of all lawsuits.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Titan Pharmaceuticals, Inc. (TTP) announced that all of the class action and derivative lawsuits filed against the company have been dismissed without prejudice. In every case, the plaintiffs...

FLAIR-MRI can detect abnormal hyperintensity within the subarachnoid space.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- FLAIR-MRI can show central nervous system (CNS) abnormalities as areas of hyperintensity, but can also show artifacts. According to recent research from Japan, "A variety of CNS diseases are...

New research may lead to orally administered small-molecule cancer drug.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- New insights into a key cancer pathway - known as p53 - have been uncovered by scientists at Roche. In a paper published in the February 6 issue of Science and Sciencexpress, for the first time,...

New web site provides online support for teens with cancer.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- The Wellness Community (TWC) announced the launch of a new web site, www.GroupLoop.org, that provides teenagers with cancer online support groups (OSGs), valuable resources and information,...

Insulin-like growth factor-I receptor fosters tumor invasion and metastasis.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Insulin-like growth factor-I receptor fosters tumor invasion and metastasis. "The breakdown of the extracellular matrix (ECM) by proteinases is an essential step in the process of cancer invasion...

Breast cancer risk differs within the South Asian female population in England.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Differences in breast cancer risk between South Asian ethnic subgroups were partly due to diet and body size, researchers say. According to a study from England, "South Asian women in England have...

Researchers develop a new protocol for verifying data.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- A statistical protocol is introduced for analyzing spatially varying data, including putative explanatory variables, researchers say. According to a study from the United States, "The procedures...

Not all tests should be advocated.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Certain screening tests for cancer are of unproven value and should not be advocated, argues a senior doctor. The blood test for cancer of the prostate (PSA) is an example, wrote Professor Malcolm...

Bill to offer cancer treatment to poor women clears first hurdle in Oklahoma.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Joan Walker, MD, sinks a little lower in her chair each time a map showing states that offer breast and cervical cancer treatment for poor women is shown at medical conferences. A lone, red...

Fourth phase II trial initiated for new stem cell transplantation drug candidate.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- AnorMED, Inc., (AOM) announced the initiation of its fourth phase II clinical trial to evaluate AMD3100 as a new stem cell transplantation drug candidate for cancer patients. Clinical data to date...

IRESSA (gefitinib) added to ASCO practice guidelines.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- An expert panel of the American Society of Clinical Oncology (ASCO) has updated their "Clinical Practice Guidelines" for the treatment of non-small cell lung cancer (NSCLC). For the first time the...

Indiana's mega-million proton therapy cancer center welcomes its first patients.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- A medical center at Indiana University that cost $40 million and has been 10 years in development has begun treating its first patients, using proton beams to destroy inoperable cancerous tumors and...

TNP-470 blocks carcinosarcoma-induced tube formation.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- TNP-470 blocks carcinosarcoma-induced tube formation. According to researchers in Japan, "we evaluated the usefulness of TNP-470 as an anticancer agent on a human uterine carcinosarcoma cell line...

The ZD55-gene therapy system is a potent anticancer tool.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- The ZD55-gene therapy system is a potent anticancer tool. According to recent research published in the journal Cell Research, "ONYX-015 is an attractive therapeutic adenovirus for cancer because...

Tumor growth is inhibited by targeted alliinase delivery.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Allilcin resulted in tumor growth arrest in a human tumor cell line xenograft in nude mice. "Allicin (diallyl thiosulfinate), a highly active component in extracts of freshly crushed garlic, is the...

Update provided on Polymer Platinate AP5346 program.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Access Pharmaceuticals, Inc., (AKC) provided an update on the status of its AP5346 Polymer Platinate Program, including the patent status, preclinical data, and the progress of the phase I clinical...

Cancer vaccines use high molecular weight stress proteins.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Scientists are developing cancer vaccines using autologous and recombinant high molecular weight stress proteins. According to published research from the United States, "High molecular weight heat...

Nutrition contributes to aging and cancer development.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- DNA methylation provides an important common link between aging, cancer, and nutrition, researchers say. "Cancer and aging are two coupled developmental processes as reflected by the higher...

Ras activation causes endothelial cells to acquire an angiogenic phenotype.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Ras activation causes endothelial cells to acquire an angiogenic phenotype. "Angiogenic factors alter endothelial cell phenotype to promote the formation of new blood vessels, a process critical for...

Research shows how cells ensure genetic material shared evenly between daughters.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Researchers at the University of Dundee have made an exciting new discovery on how cells regulate themselves and prevent cancer. Dr. Tomo Tanaka and his team members, Drs. Hilary Dewar and Kozo...

HPV, chromosome aberrations correlate with transition to microinvasive carcinoma.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Integration of human papillomavirus (HPV) 16/18 DNA is an important event in the transition of cervical intraepithelial neoplasia (CIN I, II, and III) to microinvasive carcinoma. "Cervical...

In situ hybridization techniques may be able to detect HPV.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- High-risk human papillomaviruses (HPVs) might be detected by sensitive in situ hybridization techniques. "Human papillomaviruses are accepted as a necessary cause of cervical neoplasia. However,...

Optical detection system plus colposcopy yields improved detection rates.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- In a study of more than 2,000 women, a group of physicians found that detection of precancerous changes in the cervix improved by more than 26% when a new optical detection system was used in...

Publication points to increasing use of HPV testing in cervical cancer screening.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- The first consensus guidance on the most effective way to use HPV DNA testing for cervical cancer screening has been published in the February issue of Obstetrics & Gynecology, announced Digene Corp....

Corticosteroids alone reduced cisplatin-induced delayed emesis.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Researchers report that corticosteroids significantly reduced delayed emesis caused by cisplatin and that adding metoclopramide or 5-HT[subscript]3 receptor antagonists did not offer any significant...

Lamivudine maintains adriamycin intensity in hepatitis B patients with lymphoma.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Lamivudine maintains adriamycin intensity in hepatitis B patients with lymphoma. According to researchers in South Korea, "we investigated the effectiveness of lamivudine to prevent hepatitis flare...

A model can estimate glomerular filtration rate in pediatric cancer patients.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Researchers develop a noninvasive method for estimating glomerular filtration rate (GFR) in children with cancer. "Estimation of GFR using the clearance of chromium 51 EDTA (Cr-51-EDTA) (or other...

FDA approves Spiriva HandiHaler.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Boehringer Ingelheim Pharmaceuticals, Inc., announced that the U.S. Food and Drug Administration (FDA) has approved Spiriva HandiHaler (tiotropium bromide inhalation powder) for the long-term,...

Mistrust limits minority representation in U.S. biomedical research.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Medical peer reviews are increasingly highlighting the inadequacy of minority representation in biomedical research, according to research from Frost & Sullivan. Ethnic minorities - African...

Group develops ethical strategies to use when seeking informed consent.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Researchers develop communication strategies to assist doctors in ethically obtaining informed consent to participate in cancer clinical trials. "Randomized clinical trials have come to be regarded...

Drug discovery and development collaboration amended.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Vertex Pharmaceuticals Incorporated (VRTX) announced that Vertex and Novartis Pharma AG have amended their collaboration directed at targets in the protein kinase gene family. The revised agreement...

Genetronics announces strategic alliance.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Genetronics Biomedical Corp. (GEB) announced an agreement with RMR Technologies, LLC, (RMR), where Genetronics may commercialize RMR's electroporation methods and devices on a worldwide exclusive basis....

Integrated BioPharma sub, Purdue gene-transfer study results published.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Scientists at NuCycle Therapy, a wholly owned subsidiary of Integrated BioPharma, Inc., (INB), teamed with researchers at Purdue University in a 2-year study funded by the U.S. National Institute of...

Marketing agreement signed for promotion of aspergillus test.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Bio-Rad Laboratories, Inc., (BIO; BIOb), a multinational manufacturer and distributor of life science research products and clinical diagnostics, announced that it has entered into a marketing agreement...

Milestone payment made in anticipation of NDA filing of Clofarabine.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Bioenvision, Inc., (BIV) announced that it has signed an agreement with Ilex Products, Inc., a wholly owned subsidiary of Ilex Oncology, Inc., (ILXO), in which Bioenvision has converted Ilex's option to...

A dominant-negative mutant of the c-Jun gene stems colorectal cancer growth.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- A dominant-negative mutant of the c-Jun gene stems colorectal cancer growth. "Activator protein-1 (AP-1), a transcription factor, is activated through many oncogenic signals. However, its biological...

Estrogen may have protective effect, study finds.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- For the first time, a University of Missouri-Columbia researcher has shown that estrogen may protect against colon cancer. Colon cancer is the third most common form of cancer in the United States....

Patients are moderately shocked about a screening-detected diagnosis of cancer.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Raising awareness of the adenoma-carcinoma sequence may help reduce the shock of a screen-detected diagnosis of colon cancer, researchers say. "The experience of receiving a screen-detected...

U.K.'s urgent referral standard hampered by system delays.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- The 2-week maximum wait to see a specialist for U.K. patients with suspected colon cancer does not seem to be working well, if the results of one hospital's audit are anything to go by, suggests...

Xeloda shows promising tolerability results in colon cancer study patients.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- A safety analysis from a major phase III study involving patients with early stage colon cancer shows that those receiving oral Xeloda (capecitabine) had promising tolerability results compared to those...

FDA approves Erbitux for metastatic disease.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- The U.S. Food and Drug Adminstration (FDA) has approved Erbitux (cetuximab) to treat patients with advanced colorectal cancer that has spread to other parts of the body. Erbitux is the first...

Researchers use human genome to design drugs.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Chemical genomics involves generating large collections of small molecules and systematically using them to change the way cells in the body function. In the March 2004 issue of Nature Genetics,...

Parotid may be invaded by squamous cell external auditory canal carcinoma.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Parotid excision should be performed in patients with advanced squamous cell carcinoma of the external auditory canal. "Until now, little was known about the mode of parotid involvement in external...

ERT poses little recurrence risk for women treated for early-stage disease.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- In a study conducted over a 5-year period with more than 1,200 women with early-stage endometrial cancer, a team of physicians found that estrogen replacement therapy was associated with a low incidence...

Prolonged menstruation is associated with developing endometrial cancer.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Never having been pregnant, never having given birth, and longer menstruation were associated with an increased risks of developing endometrial cancer among women in Shanghai. According to a study...

CDC asking EPA to test suspect environmental contaminant in Sierra Vista.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- Investigators from the nation's top disease-fighting agency embarked on a 1-day "field trip" in February to Sierra Vista, Arizona, the site of an alarming cluster of childhood leukemia cases. ...

Staging esophageal cancer with endoscopic MR imaging is safe.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- MR imaging to stage esophageal cancer is comparable to endoscopic ultrasound staging, but some overstaging occurred. "The authors defined esophageal anatomy and evaluated esophageal cancer staging...

Chemoradiation is effective in patients with inoperable esophageal carcinoma.
March 2, 2004... 2004 MAR 2 - (NewsRx.com & NewsRx.net) -- A regimen of radiotherapy along with cisplatin and 5-fluorouracil is tolerable and effective in patients with inoperable esophageal cancer. "We performed a retrospective study of 90 consecutive...