Cancer Weekly articles from March 2001

Cancer Weekly archives from March 2001

Anti-Angiogenesis Therapy Inhibits Growth.(Brief Article)
March 6, 2001... 2001 MAR 6 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer -- Neuroblastomas that are resistant to standard therapies may knuckle under to a novel anti-angiogenesis therapy, researchers predict. A soluble,...

Study Indicates Peripheral Blood Cells Superior To Bone Marrow For Cancer Treatment.(Brief Article)
March 6, 2001... 2001 MAR 6 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer -- Oncologists writing in the New England Journal of Medicine have shown that peripheral blood cells, properly mobilized, can be used to treat leukemia and...

p16-Gene Transfer Combined With Butyrate Improves Treatment Results.(Brief Article)
March 6, 2001... 2001 MAR 6 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer -- Researchers say p16 gene therapy of bladder cancer can be improved by the addition of butyrate. Cancer cells with strong Coxsackie-adenoviral...

Computer Program Lends New Precision To Gamma Knife Surgery.(Brief Article)
March 6, 2001... 2001 MAR 6 - (NewsRx.com & NewsRx.net) -- In a promising new research effort, a mathematical program is helping automate and fine tune the arduous process of treating brain tumors with radiation surgery. Currently the procedure...

Peptide-Based Vaccine Has Potential.(Brief Article)
March 6, 2001... 2001 MAR 6 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer -- Peptide mapping results in discovery of potential anticancer epitopes, researchers in England say. "The human epithelial mucin MUCI is over-expressed...

"Missing Link" Found Between Rare Disease And Inherited Forms Of Breast Cancer.(Brief Article)
March 6, 2001... 2001 MAR 6 - (NewsRx.com & NewsRx.net) -- Scientists following the gene trail of one of the world's rarest diseases have found it leads to an entirely unexpected place: to BRCA1, a gene that, when defective, is the most common source of...

Vinflunine Shows Promise As Anti-Vascular Agent In Tumors.(Brief Article)
March 6, 2001... 2001 MAR 6 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, staff medical writer -- Vinflunine, a new therapeutic agent that has drawn praise for its anti-vascular effects in animals, is now undergoing clinical trials in humans. If...

p53-Transduced Dendritic Cells Induce Antitumor Immune Responses.(Brief Article)
March 6, 2001... 2001 MAR 6 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer -- Dendritic cells (DCs) transduced with wild-type p53 stimulated antitumor immune responses, researchers in the United States report. "Accumulation of...

Combination p53 Gene Therapy/Paclitaxel Chemotherapy Evaluated In Vivo.(Brief Article)
March 6, 2001... 2001 MAR 6 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer -- The addition of chemotherapy to gene therapy regimens may improve therapeutic outcomes, researchers in the United States report. "SCH58500 (ACN53) is...

Autologous Dendritic Cells Shrink Metastatic Tumors.(Brief Article)
March 6, 2001... 2001 MAR 6 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer -- Intratumoral injection of autologously-derived dendritic cells (DCs) had anti-tumor activity against metastatic cancers, researchers report. "DCs are...

Finding In Bacteria Has Implications For Tumor Resistance To Chemotherapy.(Brief Article)
March 6, 2001... 2001 MAR 6 - (NewsRx.com & NewsRx.net) -- University of Minnesota scientists have found the mechanism by which certain bacteria develop resistance to a powerful antibiotic that doubles as an anti-cancer agent. Because cancer cells...

Thymidine Phosphorylase Joins VEGF As Disease Marker.(Brief Article)
March 6, 2001... 2001 MAR 6 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, staff medical writer -- New research suggests thymidine phosphorylase is a marker for progression and metastasis in gastric carcinoma, joining vascular endothelial growth factor as...

Careful Monitoring Needed Following Surgery To Detect HBV Recurrence.(Brief Article)
March 6, 2001... 2001 MAR 6 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, staff medical writer -- To eliminate the risk of acute hepatic failure after surgery for hepatocellular carcinoma, hepatitis B patients need to be carefully monitored for viral...

CpG Motifs Have Therapeutic Potential.(Brief Article)
March 6, 2001... 2001 MAR 6 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer -- CpG motifs may influence the success of vaccines, immunotherapies, and gene therapies, Genzyme Corp. researchers suggest. "The mammalian immune...

Degrees Of Pre-Cancerous Lesions Evaluated.(Brief Article)
March 6, 2001... 2001 MAR 6 - (NewsRx.com & NewsRx.net) -- Not surprisingly, cases of laryngeal keratosis, without dysplasia or with mild dysplasia, have lower rates of recurrence as well as better prognosis than more advanced cases, otorhinolaryngologists...

Dual Mechanisms Produce VEGF Up-Regulation.(Brief Article)
March 6, 2001... 2001 MAR 6 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, staff medical writer -- Vascular endothelial growth factor (VEGF) up-regulation in hepatocellular carcinoma (HCC) depends on hypoxia-related genetic changes, researchers in Germany...

PET Scans Accurate For Identifying Malignant Lesions.(Brief Article)
March 6, 2001... 2001 MAR 6 - (NewsRx.com & NewsRx.net) -- Positron emission tomography (PET) is an accurate non-invasive imaging test for diagnosis of pulmonary nodules and larger mass lesions, although few data exist for nodules smaller than 1 cm in...

Chemotherapy With Antiretroviral Regimen Is Effective In Patients With HIV And Cancer.(Brief Article)
March 6, 2001... 2001 MAR 6 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer -- Despite significant toxicity concerns, oncologists in Italy argue that combining chemotherapy and antiretroviral treatments can reduce mortality risks for...

Higher Doses Of Chemotherapy Increase Remission Time And Toxicity.(Brief Article)
March 6, 2001... 2001 MAR 6 - (NewsRx.com & NewsRx.net) -- While a regimen of moderately high-dose systemic chemotherapy followed by additional chemotherapy placed in the abdomen produces longer remissions in women with advanced ovarian cancer, the strategy...

Abnormal Production Of Cell Receptors Plays Role In Tumor Invasion.(Brief Article)
March 6, 2001... 2001 MAR 6 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, staff medical writer -- Abnormal production of fibroblast growth factor-1 may be one reason for prostate cancer related tumor invasion, suggest medical researchers at the...

Advanced Programming Techniques Improve Brachytherapy.(Brief Article)
March 6, 2001... 2001 MAR 6 - (NewsRx.com & NewsRx.net) -- A merger of advanced mathematical techniques with cutting-edge computer technology may give doctors a powerful new weapon in the battle against prostate cancer. Researchers have developed a...

Treatment With Magnetic Rods Studied.(Brief Article)
March 6, 2001... 2001 MAR 6 - (NewsRx.com & NewsRx.net) -- University of Iowa researchers are developing a new approach to treat prostate cancer using heat generated by implanted magnetic rods to destroy the cancer. The UI scientists hope the new...

Restoration Of p53 Function Causes Cell Death.(Brief Article)
March 6, 2001... 2001 MAR 6 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer -- An alternative therapy offers hope for patients with hard-to-treat anaplastic Wilms' tumors. "Recent studies have reported a high incidence of p53...

Genome Project's Likely Impact: Limited In Short Term, Unpredictable In Long Term.(Brief Article)
March 13, 2001... 2001 MAR 13 - (NewsRx.com & NewsRx.net) -- Completion of the Human Genome Project will influence the general framework for anticancer drug development but not fundamentally alter it any time soon, predict two cancer specialists in a...

Link Found Between Cutaneous Melanoma And Non-Hodgkin's Lymphoma.(Brief Article)
March 13, 2001... 2001 MAR 13 - (NewsRx.com & NewsRx.net) -- A significant association exists between cutaneous melanoma and non-Hodgkin's lymphoma, according to a study published in the February 15, 2001, issue of Cancer. The authors report a...

Can Simply Swallowing A Gene Actually Treat And Prevent Cancer?
March 13, 2001... 2001 MAR 13 - (NewsRx.com & NewsRx.net) -- Cancer geneticists and neuroscientists report stunning results in a gene therapy experiment in laboratory mice. Researchers, led by Carlo Croce, MD, professor and chair of microbiology and...

Surprisingly Large Gaps Found In Research.(Brief Article)
March 13, 2001... 2001 MAR 13 - (NewsRx.com & NewsRx.net) -- Although there is a huge body of scientific research on cancer biology, the quality and quantity of research on the management of cancer pain lags far behind, according to researchers at the New...

Gene Confirmed In Both Benign And Malignant Tissue.(c-kit found in both benign and malignant endometrial tissue)
March 13, 2001... 2001 MAR 13 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer -- Researchers have confirmed the presence of the gene c-kit in both benign and malignant endometrial tissue, laying to rest previously contradictory...

Interleukin-6 Is Associated With Resistance, Relapse.(multiple myeloma complications)
March 13, 2001... 2001 MAR 13 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer -- The greater the production of interleukin-6, the more aggressive multiple myeloma will prove to be, according to a report in Blood. Researchers...

Mutation Critical To Development Of Pre-Cancerous Condition.(squamous cell carcinoma in situ)
March 13, 2001... 2001 MAR 13 - (NewsRx.com & NewsRx.net) -- A mutation that prevents skin cells from making normal connections with each other plays an unexpectedly early and important role in the development of the skin cancer, suggests a study published...

Bacterium May Teach Scientists How To Kill Cancer Cells.(Pseudomonas aeruginosa)
March 13, 2001... 2001 MAR 13 - (NewsRx.com & NewsRx.net) -- With a new four-year, $1 million grant from the American Cancer Society, microbiologist Shouguang Jin, at the University of Florida, is seeking a better understanding of how the bacterium...

Researchers Clarify Best Methods Of Gene Delivery To Tumors.(Brief Article)
March 13, 2001... 2001 MAR 13 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer -- The effectiveness of delivering genetic material to mice with bladder cancer can vary widely. Physical delivery methods affect therapeutic efficacy...

Four More Genes Identified That May Play Role In Development Of Malignant Tumors.(malignant brain tumors)
March 13, 2001... 2001 MAR 13 - (NewsRx.com & NewsRx.net) -- Using technology that enables them to analyze 18,000 genes in a single experiment, researchers at Cedars-Sinai Medical Center's Maxine Dunitz Neurosurgical Institute have identified four genes that...

Peptide Antagonist Reduces Orthotopic Tumors In Mice.(EMD 121974 reduces orthotopic brain tumors)
March 13, 2001... 2001 MAR 13 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, staff medical writer -- A new peptide antagonist demonstrates substantial anti-angiogenic effects on orthotopic brain tumors transplanted into mice. The antagonist, called...

Study Reveals Mechanism Of Non-Hereditary Breast And Ovarian Cancers.(Brief Article)
March 13, 2001... 2001 MAR 13 - (NewsRx.com & NewsRx.net) -- A new study has provided unexpected new evidence of a mechanism for non-hereditary breast and ovarian cancer. Researchers found the hypermethylation of the BRCA1 gene was found to "turn off"...

Understanding Protein "Motor" May Help Disable Abnormal Cell Growth.(Brief Article)
March 13, 2001... 2001 MAR 13 - (NewsRx.com & NewsRx.net) -- Scientists studying cellular division have longed for clues to how cancer cells are able to divide so rapidly. Now, studies by Ohio University biochemists are offering several new pieces needed to...

Increasing Copper Consumption May Be Protective.(against colorectal cancer)
March 13, 2001... 2001 MAR 13 - (NewsRx.com & NewsRx.net) -- Take some oysters, liver, nuts, and seeds, wash them down with a little cocoa, and top them off with a chocolate bar for dessert. While this combination may not appeal to your taste buds,...

New Studies Identify Patients At High Risk For Advanced Disease Or Best Suited For Surgery.(colorectal cancer diagnosis)
March 13, 2001... 2001 MAR 13 - (NewsRx.com & NewsRx.net) -- Four studies published in the February 2001 issue of Diseases of the Colon and Rectum point to new ways for physicians to identify colorectal cancer patients best suited for surgery and those at...

Lower Doses Of Interleukin-12 Are More Lethal To Tumors.
March 13, 2001... 2001 MAR 13 - (NewsRx.com & NewsRx.net) Less is more, say researchers who have uncovered an unexpected dose-dependent relationship between interleukin-12 (IL-12) and tumor suppression. IL-12 appears to stimulate immune response to...

Scientists Define Histological Characteristics Before, After Bone Marrow Transplant.(Brief Article)
March 13, 2001... 2001 MAR 13 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer -- Researchers working in Germany have systematically defined several histopathological features in leukemia patients undergoing bone marrow transplant. ...

Drugfacts.Com, NewsRx Collaboration Expands Availability Of Custom Health News For Professionals.
March 13, 2001... 2001 MAR 13 - (NewsRx.com & NewsRx.net) -- Drugfacts.com, the premier free drug information resource on the Internet for pharmacists and other healthcare professionals, and NewsRx, the leading provider of daily and weekly health news, have...

Monoclonal Antibodies Deliver Therapy To Targeted Tumors.(pancreatic cancer)
March 13, 2001... 2001 MAR 13 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer -- Monoclonal antibodies (MAbs) show promise in targeted therapies for pancreatic cancer. The ability of MAbs to deliver drugs or radionuclides to...

New Vaccine Appears Safe, Effective.(against pancreatic tumors)
March 13, 2001... 2001 MAR 13 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer -- A vaccine that stimulates an immune response against pancreatic tumors appears to be safe and effective in humans. The ability to prolong...

Conservative Surgery Sparing Larynx Is Okay For Posterior Wall Tumors.
March 13, 2001... 2001 MAR 13 - (NewsRx.com & NewsRx.net) -- by Maryclaire Lindgren, staff medical writer -- Conservative surgery that spares the larynx followed by radiation is satisfactory for treating posterior pharyngeal wall carcinomas, researchers in...

Study Of Mass Screening Indicates Need For Repeated Testing.(Brief Article)
March 13, 2001... 2001 MAR 13 - (NewsRx.com & NewsRx.net) -- Prostate carcinoma screening is recommended every three years in men age 50 years or older with initial prostate-specific antigen (PSA) levels of The prostate carcinoma detection rate increases...

Protein Linked To Cancer Cell Immortality.(Brief Article)
March 20, 2001... 2001 MAR 20 - (NewsRx.com & NewsRx.net) -- One of the hallmarks of a cancer cell is its immortality - its ability to divide endlessly. A pair of Harvard Medical School researchers has identified a protein that some 10% of tumor cells seem...

Dana-Farber Treatment Protocol Improves Outcome.(Brief Article)
March 20, 2001... 2001 MAR 20 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer -- The more intensive 1991 version of the Dana-Farber treatment protocol can dramatically improve survival chances for acute lymphoblastic leukemia patients....

Scientists Detail Key Molecular Pathway and Potential Drug Targets Against Cancer, Neurodegenerative Disease.(Brief Article)
March 20, 2001... 2001 MAR 20 - (NewsRx.com & NewsRx.net) -- Molecular geneticists at the Kimmel Cancer Center of Jefferson Medical College are uncovering clues to how and why cancer cells grow with abandon, while at the same time, understanding why brain...

Physicians In Outpatient Oncology Practice Fail To Identify Or Treat Pain.(Brief Article)
March 20, 2001... 2001 MAR 20 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer -- Oncologist need more education in identifying cancer patients in pain, researchers in the United States report. "Although physicians view failure to...

Epstein-Barr Virus Linked To Invasive Breast Cancer And Lymphoma.(Brief Article)
March 20, 2001... 2001 MAR 20 - (NewsRx.com & NewsRx.net) -- Scientists at the University of Michigan Medical School have found a molecular link between aggressive breast and lymphatic cancers and the Epstein-Barr virus, which causes infectious...

Growth Factors Predict Response And Prognosis After Therapy.(Brief Article)
March 20, 2001... 2001 MAR 20 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, staff medical writer -- Basic fibroblast growth factor (bFGF) is an important prognostic indicator in patients with lung cancer, researchers in Japan say. Those researchers,...

Common Drug Prevents Spread Of Cancer In Mice.(Brief Article)
March 20, 2001... 2001 MAR 20 - (NewsRx.com & NewsRx.net) -- University of California, San Diego, Cancer Center researchers have obtained evidence that the common anticoagulant drug heparin diminishes metastasis of certain cancers in mice by interfering with...

Interleukin-6 Is Too Toxic For Use After Pediatric Chemotherapy.(Brief Article)
March 20, 2001... 2001 MAR 20 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer -- Oncologists warn that interleukin-6 (IL-6), while effective at improving hematopoietic recovery, is too toxic for use in children undergoing chemotherapy....

Oligonucleotide Therapy Fails To Target Ki-ras Valine Point Mutation.(Brief Article)
March 20, 2001... 2001 MAR 20 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer -- Efforts to target a gene mutation associated with aggressive colorectal cancer have met with little success. Researchers working in England focused...

Screening Should Begin Earlier For Certain Ethnic Groups.(Brief Article)
March 20, 2001... 2001 MAR 20 - (NewsRx.com & NewsRx.net) -- Screening for colon and rectal cancer at earlier ages among some ethnic groups may pay off in lower rates of cancer incidence and deaths in those groups, a University of California, Irvine, College...

Endoscopic Screening Using Iodine Staining Facilitates Early Diagnosis.(Brief Article)
March 20, 2001... 2001 MAR 20 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer -- Iodine staining may facilitate early diagnosis of esophageal cancer, researchers in Japan report. Normal procedures, including endoscopic screening,...

Parotid-Sparing Radiotherapy Preserves Salivary Output.(Brief Article)
March 20, 2001... 2001 MAR 20 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer -- Paratid-sparing radiotherapy improves quality of life (QOL) for head and neck cancer patients, according to a study from the United States,. ...

Tirapazamine, Cisplatin, And Radiotherapy Are Relatively Well-Tolerated.(Brief Article)
March 20, 2001... 2001 MAR 20 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer - Patients with advanced head and neck squamous cancer tolerate concurrent chemotherapy and radiotherapy relatively well, researchers in Australia say. ...

Clinical Trials Focus On New Treatment Approaches.(Brief Article)
March 20, 2001... 2001 MAR 20 - (NewsRx.com & NewsRx.net) -- The University of Maryland Greenebaum Cancer Center will be the first site in the world to offer leukemia patients a new drug known as MS-275, which is also being studied by the U.S. National...

AFP-Enhanced Gene Therapy Boosts Ganciclovir Efficacy.(Brief Article)
March 20, 2001... 2001 MAR 20 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer -- Human alpha-fetoprotein (AFP) appears to enhance the ability of a viral vector to deliver therapy to liver cancer cells. Researchers working in Japan...

Gene Transfer Can Protect Hematopoietic Stem Cells.(Brief Article)
March 20, 2001... 2001 MAR 20 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer -- Drug resistance genes have the potential to protect hematopoietic stem cells and to increase their numbers - a boon to cancer patients receiving...

Biopsy Is Crucial For Diagnosis Of Mouth Neoplasms.(Brief Article)
March 20, 2001... 2001 MAR 20 - (NewsRx.com & NewsRx.net) -- by Michelle Marble, staff medical writer - Periodontal masses of the mouth can have numerous diagnoses, and a biopsy is crucial for correct treatment, researchers in Italy assert. "Liposarcoma...

High Serum Protein Levels Predict Negative Outcome.(Brief Article)
March 20, 2001... 2001 MAR 20 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer -- Researchers in Japan have shown that serum protein nm23-H1 levels can be used to predict mortality risks for non-Hodgkin's lymphoma (NHL) patients. ...

Rituximab Shown Safe, Effective With Chemotherapy.(Brief Article)
March 20, 2001... 2001 MAR 20 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer -- Response rates were promising in the first study of non-Hodgkin's lymphoma (NHL) patients given the anti-CD20 monoclonal antibody rituximab along with...

Study Results Support Progestin Use To Reduce Risk.(Brief Article)
March 20, 2001... 2001 MAR 20 - (NewsRx.com & NewsRx.net) -- Medical prevention of ovarian cancer may be possible for all women in the future, according to Duke Comprehensive Cancer Center researchers in North Carolina. They report finding a second...

Tumor Cells In Bone Marrow Linked To Early Relapse, Death.(Brief Article)
March 20, 2001... 2001 MAR 20 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer -- Identification of tumor cells in the bone marrow of patients with Stage I or II ovarian cancer is strongly linked with early relapse and death from the...

Parents' Accounts Help In Diagnosis Of Childhood Cancer.(Brief Article)
March 20, 2001... 2001 MAR 20 - (NewsRx.com & NewsRx.net) -- Health professionals should value the concern and knowledge of parents about their children to help in the diagnosis of childhood cancers, conclude authors of a study published in the March 3,...

BAL Neopterin May Be Novel Marker For TB And Lung Cancer Disease States.(bronchoalveolar lavage)
March 27, 2001... 2001 MAR 27 - (NewsRx.com & NewsRx.net) -- Researchers in Egypt say neopterin levels in bronchoalveolar lavage (BAL) fluid may be a useful marker for disease activity in tuberculosis and some lung cancers. Prior research has identified...

Delivery Of Genes To Leukemia Cells Offers Promise For Cancer Vaccine.
March 27, 2001... 2001 MAR 27 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - Gene transfer to leukemic cells via a lentivirus vector may one day be useful in the development of a cancer vaccine. "We adopted a defective...

Early Detection Does Not Improve Treated Patients' Quality Of Life.(prostate cancer)
March 27, 2001... 2001 MAR 27 - (NewsRx.com & NewsRx.net) -- Treatment for prostate cancer has a considerable impact on a patient's quality of life, regardless of the therapy used, or how early their cancer was initially detected, a Dutch study has...

NAEPP Protocol Is Effective For Relapsed Elderly Patients.(non-Hodgkin's lymphoma in the elderly can be treated with vinorelbine, epirubicin, and prednisone)
March 27, 2001... 2001 MAR 27 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Elderly patients suffering from non-Hodgkin's lymphoma (NHL) may benefit from treatment with the NAEPP (vinorelbine, epirubicin, and prednisone) protocol....

Isolated Limb Perfusion Technique To Deliver Chemotherapy Is In Clinical Trials.(for treatment of advanced melanoma)
March 27, 2001... 2001 MAR 27 - (NewsRx.com & NewsRx.net) -- Roswell Park Cancer Institute (RPCI), Buffalo, New York, is participating in an American College of Surgeons Oncology Group (ACOSOG) multi-center, randomized clinical trial to evaluate the benefits...

VEGF Levels Correspond With Poor Prognosis In Non-Small Cell Lung Cancer.(vascular endothelial growth factor)
March 27, 2001... 2001 MAR 27 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, staff medical writer - Vascular endothelial growth factor (VEGF) has prognostic value for patients with non-small cell lung cancer, scientists say. Researchers at Allegheny...

Pre-Operative Chemoimmunotherapy For Unresectable Tumors Can Induce Remission.(in liver cancer)
March 27, 2001... 2001 MAR 27 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, staff medical writer - Patients with inoperable liver cancer could benefit by being given chemoimmunotherapy and then surgery. Medical researchers in China, using newer...

Pre-Operative VEGF Level Is Biomarker For Vascular Invasion In Liver Cancer.(vascular endothelial growth factor)
March 27, 2001... 2001 MAR 27 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, staff medical writer - A new study indicates pre-surgical serum vascular endothelial growth factor (VEGF) levels predict microvessel invasion in liver cancer patients. R.T.P....

Modified Adenovirus-Based Gene Therapy To Be Tested For Recurrent Cancer.(of the head and neck)
March 27, 2001... 2001 MAR 27 - (NewsRx.com & NewsRx.net) -- The University of North Carolina at Chapel Hill School of Medicine is one of nine medical centers in the U.S. trying to determine if injections of a genetically modified common cold virus may be an...

Hepatitis B and C Linked To Non-Hodgkin's Lymphoma In Japan.
March 27, 2001... 2001 MAR 27 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, staff medical writer - Hepatitis B and C viruses associate with non-Hodgkin's lymphoma, especially in males, researchers in Japan say. A study conducted by Masami Kuniyoshi...

Vaccine Targeting p53 Antigen Could Prolong Survival.(for colorectal cancer patients)
March 27, 2001... 2001 MAR 27 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - A vaccine boosting levels of anti-p53 immunity in colorectal cancer patients could prolong disease-free survival, suggest researchers working in The...

High Rates Of HBV And HCV Are Blamed For Growing Incidence of Liver Cancer In Egypt.(Hepatitis B and C)
March 27, 2001... 2001 MAR 27 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, staff medical writer - Hepatocellular carcinoma is increasing in Egypt because of high rates of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections. Hepatocellular...

Quantitative Polymerase Chain Reaction Tests Can Predict Transplant Outcome.(stem cell transplantation for chronic myeloid leukemia)
March 27, 2001... 2001 MAR 27 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Quantitative reverse transcriptase-polymerase chain reaction (RT-PCR) testing after stem cell transplantation can help determine further treatment for...

Patient Enrollment Complete For Pivotal Xcytrin Phase III Trial For Brain Metastases.
March 27, 2001... 2001 MAR 27 - (NewsRx.com & NewsRx.net) -- Pharmacyclics, Inc. (PCYC), announced on March 14, 2001, that patient enrollment has been completed in its pivotal international, randomized, controlled Phase III clinical trial of Xcytrin(R)...

Targeting Cdk Inhibitor Can Lead To Tumor Suppression.(cyclin-dependent kinase expression can lead to breast tumor suppression)
March 27, 2001... 2001 MAR 27 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - Gene transfer to mice with mammary cancer can induce expression of cyclin-dependent kinase (Cdk) inhibitor p21 and lead to tumor suppression, say...

New Blood Vessel Growth Related To Tumor Recurrence After Dormancy.(in breast cancer)
March 27, 2001... 2001 MAR 27 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, staff medical writer - Scientists in Italy suggest that breast cancer patients with substantial blood vessel growth in their primary tumors have a greater chance for tumor...

Cytokine-Secreting Vaccine Stops Metastatic Brain Tumors In Mice.
March 27, 2001... 2001 MAR 27 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - Mice vaccinated with allogeneic fibroblasts that secrete interleukin 2 are less likely to develop metastatic brain tumors arising from breast cancer. ...