Cancer Weekly articles from June 2003

Cancer Weekly archives from June 2003

Tumor cell sensitivity - then resistance - to chemotherapy linked to gene.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Researchers at Dana-Farber Cancer Institute and a team of international collaborators have identified a genetic abnormality that makes some ovarian tumor cells initially sensitive to a common...

Scientists uncover role of Fanconi anemia genes.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Scientists at the Johns Hopkins Kimmel Cancer Center have identified three genes, long linked to a rare inherited disease known as Fanconi anemia (FA), that now appear to play a role in many cases of...

Lower survival for black women under 50 may be due to differences in treatments.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Researchers say there appears to be evidence of racial differences in treatment of breast cancer among women under 50, since survival rates by stage-at-diagnosis for younger black women are lower than...

Cell migration is the object of vascular targeting by combretastatin A-4.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Cell migration is the object of vascular targeting by combretastatin A-4. "The current research aimed to define hypothesis-based antiangiogenic properties of the vascular targeting agent...

High-calorie diet seems to increase chances of surviving longer.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- A high-calorie diet seems to increase the chances of surviving bowel cancer for longer, suggests new research. Bowel cancer is one of the most common cancers in the West and is strongly linked to...

Radioactive seed implantation safe and effective as alternative to surgery.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- In the first long-term study of real-time radioactive seed implantation as a treatment for prostate cancer, researchers at Mount Sinai School of Medicine have confirmed it to be a safe and effective...

Gene dosage aids detection of 9p21 deletions in children.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Gene dosage aids the detection of chromosome abnormalities in pediatric leukemia patients. "Deletion of the 9p21 chromosomal region is frequently found in childhood acute lymphoblastic leukemia...

Intensified GVHD prophylaxis enables haploidentical stem cell transplants.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Intensified prophylaxis against graft-versus-host reactions enables haploidentical stem cell transplantation for acute lymphoblastic leukemia patients. Researchers in Japan described their...

Dust mite allergy increases the risk of prostate cancer.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Breast and lung cancer have no allergy-related association, but dust mite allergy increases the risk of prostate cancer. "The associations among certain allergic disorders, atopy upon skin-prick...

Antithymocyte globulin and cyclosporine can lead to Merkel cell carcinoma.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Antithymocyte globulin and cyclosporine therapy can lead to development of Merkel cell carcinoma. According to published research from Japan, "We report a patient who developed Merkel cell...

Ascorbic acid modifies the surface of asbestos, removing iron and silica.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Ascorbic acid, a component of human lung lining, breaks asbestos down, releasing iron and silica as products, and may thus be involved in pathogenesis. According to recent research from Italy,...

Dexamethasone and anti-IgM apoptosis will not occur if Ik-6 is overexpressed.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Overexpression of Ik-6 appears to confer resistance to apoptosis in 2 different cell lines with differing mechanisms. "In previous studies, we demonstrated an over-expression of the...

Acquired von Willebrand syndrome occurs in some geriatric patients.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Acquired von Willebrand syndrome is an uncommon bleeding disorder that occurs in old age and may first appear with gastrointestinal bleeding or postoperatively, and can also be associated with...

Lymphoproliferative disorder can have EBV infection in both B and T cells.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Lymphoproliferative disorder having EBV infection in both B and T cells can occur as a result of bone marrow transplant. "Post-transplantation lymphoproliferative disorder (PTLD) is usually an...

1100delC may be the only CHEK2 allele that contributes to breast cancer.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- 1100delC may be the only CHEK2 allele that contributes to breast cancer. According to a study from England, "We recently reported that a sequence variant in the cell-cycle-checkpoint kinase CHEK2...

Absorption and metabolism determined the tissue pharmacokinetics of capecitabine.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Absorption and metabolism determined the tissue pharmacokinetics of capecitabine. According to recent research from Austria, "Capecitabine is an oral prodrug of 5-fluorouracil (FU). "Since FU...

Biological markers or lack thereof are predictive of clinical recurrence.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Ductal carcinoma in situ breast cancer runs a risk of recurrence if the immunohistological biomarkers for bcl-2 and estrogen and progesterone receptors are negative and the ERBB2 is positive. ...

Molecular analysis of early lesions may be key to choosing best treatment.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- A team of researchers from Massachusetts General Hospital (MGH) and the biotechnology company Arcturus has discovered molecular changes occurring in early stages of breast cancer that characterize the...

Other active and safer SERMs and aromatase inhibitors need to be developed.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Other active and safer SERMs and aromatase inhibitors need to be developed. "Clinical trials of the selective estrogen receptor modulator (SERM), tamoxifen, have shown an early reduction in risk of...

Overexpression of KCNK9 in cell lines promotes tumor formation.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Overexpression of KCNK9 in cell lines promotes tumor formation. "Representational difference analysis (RDA) of human breast cancer was used to discover a novel amplicon located at chromosomal...

Sentinel lymph node biopsy is accurate for staging.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Sentinel lymph node (SLN) biopsy is useful for staging breast cancer and is associated with fewer complications than more extensive axillary lymph node dissection, which has been considered the standard...

Tissue bank lowers cost of materials.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Detroit-based research company Asterand announced that it is lowering costs of research materials for breast cancer to help draw attention to a charity event called "The Race for the Cure." ...

Mammograms read by specialists save patients' time and money.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Results of a recent study show that breast-imaging specialists are more efficient than general radiologists at reading mammograms, said Martha Mainiero, MD, of Brown Medical School and Rhode Island...

DNA methylation markers are promising future tools in the clinic.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- DNA methylation markers are promising future tools in the clinic. According to recent research published in the journal Nature Reviews Cancer, "The past few years have seen an explosion of interest...

TNF-alpha production induced from human monocytes by beta-1,3-glucan oligomer.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- A beta-1,3-glucan oligomer from laminarin induces tumor necrosis factor (TNF)-alpha production from human peripheral blood monocytes, Nagasaki University scientists demonstrated. "We prepared a...

Cancer now No. 1 cause of death in U.K. men.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Cancer is now the biggest killer of British men, overtaking heart disease for the first time, according to new figures released by Cancer Research UK in May. Death rates from cancer have actually...

Vascular growth factor predicts recurrence in liver cancer patients.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - A growth factor that modulates angiogenesis, or neovascularization, is a biomarker for the risk of primary liver cancer recurrence. According to medical...

Homocysteine is a strong suppressor of human tumor cell gelatinases.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Homocysteine is a strong suppressor of human tumor cell gelatinases. According to recent research published in the journal Biochemical and Biophysical Research Communications, "extracellular...

Permission given to initiate LEP-ETU clinical trial.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- NeoPharm, Inc., (NEOL) announced that it has received permission from the U.S. Food and Drug Administration (FDA) to proceed with planned phase I clinical trials for LEP-ETU, the company's NeoLipid...

Antibody mimic CO17-1A elicits immune response in colorectal cancer patients.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- An antibody mimicking the gastrointestinal carcinoma-associated epitope CO17-1A elicited an immune response in colorectal cancer patients. According to published research from the United States,...

Costimulatory molecule vaccine effective against B-cell lymphoma in mice.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - A vaccine containing recombinant fowlpox virus encoding B7-1, intercellular adhesion molecule-1, and leukocyte function-associated antigen-3 elicited...

Oncogene-expressing stem cells downregulate tumor suppressor BRCA1.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Hematopoietic stem cells expressing the oncogene BCR-ABL downregulate a key anti-cancer molecule, researchers in France report. "BCR-ABL fusion oncogene is...

First results released from largest diet-cancer study ever undertaken.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- The first results from the largest scientific study to ever investigate the links between diet and cancer risk are in, and they strongly support a role for dietary fiber in the prevention of colon...

PET scans are superior to CT scans for detecting metastasis.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Results of a recent study show that 18FDG-PET studies are very accurate in detecting colon cancer spread and should be used for the staging or restaging of patients with this disease, said Simin...

p53 Protein is a mechanism of resistance to amifostine-induced apoptosis.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- p53 Protein is a mechanism of resistance to amifostine-induced apoptosis. According to a study from the United States, "To determine the role of p53 protein on the cellular effects of amifostine, we...

MR colonoscopy is noninvasive, safe, and highly accurate.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- MR colonoscopy is noninvasive, safe, and highly accurate. According to a study from Germany, "MR colonoscopy is suitable for colorectal cancer screening. "This imaging modality is noninvasive,...

Ets-1 marks angiogenic potential and prognosis in colorectal carcinomas.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Ets-1 marks angiogenic potential and prognosis in colorectal carcinomas. "We investigated Ets-1 expression and its influence on angiogenesis and survival using immunohistochemistry of surgical...

Increased dysadherin expression lowers patient survival.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- In colorectal cancer, presence and increase in the protein dysadherin lowered patient prognosis and survival. According to recent research published in the British Journal of Cancer, "A novel...

S-1 active in advanced colorectal cancer.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- S-1 is active in advanced colorectal cancer. According to recent research from Belgium, "Cancer of the colon and rectum is one of the most frequent malignancies both in the U.S. and Europe. ...

Significant public misconceptions persist about cancer screening.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Nearly 40% of colorectal cancer specialists surveyed worldwide say the most common misconception about colorectal cancer screening is that the exam is painful. More than one-quarter (28%) of experts...

Lipopolysaccharide not needed for T-cell response to DNA vaccination.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Lipopolysaccharide was not needed to induce T-cell responses to a DNA vaccine. According to a study from the United States, "Bacterial products, including lipopolysaccharide (LPS), are potential...

A novel integrin antagonist induces apoptosis in angiogenic endothelial cells.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- According to a study from Canada, "Integrin-mediated cell adhesion is necessary for endothelial cell proliferation and apoptosis, which is a major determinant in tumor-induced angiogenesis. In this...

Dyskeratosis congenita is associated with three malignancies many years later.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Dyskeratosis congenita is associated with three malignancies many years later. According to recent research published in the Journal of the European Academy of Dermatology and Venereology,...

Gene mutation in some uterine tumors may signal that cancer runs in family.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Testing younger women with endometrial cancer for mutations in a certain gene might help identify families at risk for inherited cancers, according to a study led by Washington University School of...

Radiotherapy may be a treatment of choice for liver metastasis.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Radiotherapy may be a treatment of choice for liver metastasis. According to recent research from Japan, "Recently, aggressive hepatectomies or hepatic arterial infusion chemotherapy for liver...

Bilateral fetal rhabdomyomatous nephroblastoma occurs in a 10-month-old baby.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Bilateral fetal rhabdomyomatous nephroblastoma can occur in a 10-month-old baby. "Bilateral fetal rhabdomyomatous nephroblastoma is a rare variant of Wilms' Tumor," scientists in Switzerland report....

KOC is a novel molecular indicator of malignancy.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- KOC is a novel molecular indicator of malignancy. "The detection of malignant cells in fine-needle aspirates (FNA's) using marker genes is hampered by the fact that these markers are only expressed...

CA 72-4 antigen can be considered the marker of choice in patient follow-up.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- CA 72-4 antigen can be considered the marker of choice in patient follow-up. "To date no general agreement has been reached regarding the prognostic significance of CEA, CA 19-9 and CA 72-4 as serum...

Lysophosphatidic acid is an angiogenic mediator in ovarian cancer.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Lysophosphatidic acid is an angiogenic mediator in ovarian cancer. According to a study from Japan, "lysophosphatidic acid (LPA) receptors including LPA(1), LPA(2), and LPA(3) mediate...

Multiple assays confirm esophageal cancer rib marrow micrometastasis.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Multiple assays confirm esophageal cancer rib marrow micrometastasis. "In the present study, micrometastasis in the rib marrow of 24 patients with esophageal cancer was examined using RT-PCR. RT-PCR...

Bilateral irreversible hearing loss is associated with chemotherapy.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Bilateral irreversible hearing loss is associated with chemotherapy. "The regimen with paclitaxel and platinum compound (carboplatin or cisplatin) is the standard chemotherapy for patients with...

The virulence gene cagA and MUC2 mucin are linked with cancer risk.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Helicobacter pylori cag A virulence gene is upregulated in precancerous and cancerous lesions, and these lesions specifically produce the MUC2 mucin. "Gastric intestinal metaplasia (IM) and gastric...

Tube cholangio-jejunal bypass performed in unresectable hepatic hilar carcinoma.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Tube cholangio-jejunal bypass performed in unresectable hepatic hilar carcinoma. "A 76-year-old male patient with jaundice was diagnosed as having hepatic hilar cholangiocarcinoma. The patient...

Homozygous deletion scanning reveals alternative pathways for carcinogenesis.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Homozygous deletion scanning reveals alternative pathways for carcinogenesis. "Despite high rates of loss of heterozygosity affecting various chromosomes, the number of tumor suppressor genes (TSGs)...

Enhanced specific gene expression is a new strategy for treating liver cancer.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Enhanced specific gene expression is a new strategy for treating liver cancer. "Alpha-fetoprotein (AFP) is a specific tumor marker for hepatocellular carcinoma (HCC). A gene expression system under...

Hemolysis and hemoglobinuria occur during radiofrequency ablation of liver tumor.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Hemolysis and hemoglobinuria occur during radiofrequency ablation of liver tumor. According to a study from the People's Republic of China, "Radiofrequency ablation is a safer and effective...

Macrophage inflammatory protein marks a therapy's efficacy against liver cancer.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Macrophage inflammatory protein marks a therapy's efficacy against liver cancer. "Macrophage inflammatory protein (MIP-3alpha) is a CC chemokine that attracts immature dendritic cells and...

Strong association seen between penile SCC and the presence of HPV DNA.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- There is a strong association between penile SCC and the presence of HPV DNA. According to published research from France, "Human papillomaviruses (HPV) are thought to be involved in penile squamous...

Image-enhancing tool could improve cancer diagnosis and treatment.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- An image-enhancing tool that could lead to both earlier diagnosis and improvements in monitoring treatment of cancers has been developed by researchers at the University of Texas at Austin College of...

MDCT shows promise in detecting urinary tract cancers.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Multidetector CT is faster and much more accurate than excretory urography in detecting urinary tract cancers and other urinary tract diseases, a new study suggests. The study reviewed 370 patients...

Technique developed for serial in vivo imaging of antigen-specific T cells.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Researchers with the Memorial Sloan Kettering Cancer Center, New York, have developed a technique for serial in vivo imaging of antigen-specific T cells. G. Koehne and colleagues explained that they...

Cutaneous B-cell pseudolymphoma is a recurrent risk years after antigen therapy.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Cutaneous B-cell pseudolymphoma has a risk of recurrence and dissemination years after intradermal antigen therapy. Recent research published in the Journal of the European Academy of Dermatology...

Lipoxins work towards resolution of intestinal and other inflammations.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Naturally occurring and synthetic lipoxins are responsible for attenuation of the inflammatory response. "Many inflammatory processes are self-limiting, suggesting the existence of endogenous...

Extreme heat effective for treatment.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Image-guided radiofrequency ablation - using heat to destroy cancers - can preserve kidney function and avoid kidney dialysis for patients with solid renal tumors who are not surgical candidates, a new...

Acute myeloid leukemia can be associated with necrotizing temporal arteritis.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Acute myeloid leukemia can be associated with necrotizing temporal arteritis. According to published research from the United States, "The clinical presentation of new onset headache, temporal...

Dexamethasone induced leukemic cell apoptosis and decreased cell count.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Dexamethasone induced leukemic cell apoptosis and decreased cell count. According to recent research from Turkey, "This study was performed to investigate the effects of dexamethasone on acute...

Johnson & Johnson awards $180,000 grant for drug research.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- What do leukemia, the evergreen plum-yew tree in southeast Asia, and California Institute of Technology faculty member Brian Stoltz have in common? Stoltz, an assistant professor of chemistry, is...

MOZ gain of function contributes to leukemogenesis.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- MOZ gain of function contributes to leukemogenesis. "The MOZ-TIF2 fusion is associated with acute myeloid leukemia (AML) with inv(8)(p11q13). MOZ is a MYST family histone acetyltransferase (HAT),...

Magnolol induces apoptosis in human leukemia cells.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Magnolol induces apoptosis in human leukemia cells. "Magnolol, isolated from the stem bark of Magnolia officnalis, was found to inhibit proliferation of human HL-60 cells and Jurkat T leukemia...

Methotrexate infusions significantly reduced CNS-related relapses in children.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Methotrexate infusions significantly reduced CNS-related relapses in children. "This study included all 690 children in Norway diagnosed as having acute lymphocytic leukemia (ALL) from July 1975...

PTEN protein may be absent in B-CLL with a normal PTEN genotype.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- PTEN protein may be absent in B-CLL with a normal PTEN genotype. According to a study from Switzerland, "One fifth of B-cell chronic lymphocytic leukemia (B-CLL) patients exhibit loss of...

Primary liver cancer treated successfully by chemoembolization and radiotherapy.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Primary liver cancer is treated successfully by chemoembolization and radiotherapy. "For unresectable primary liver cancer, transcatheter arterial chemoembolization is the most effective method in...

Percentage of liver remaining is predictive of degree of hepatic function.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- The percentage of liver remaining in hepatic resection is predictive of risk relating to hepatic function and length of hospital stay. According to a study from the United States, "Liver-enhancing...

Coexposure with magnetic fields and vinblastine increases effect on lymphocytes.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Low frequency magnetic fields can increase cell proliferation in normal lymphocytes and even enhances micronucleus and apoptosis frequency in lymphocytes given vinblastine. "Interference of 50 Hz,...

Iressa approved by FDA.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- AstraZeneca Pharmaceuticals (AZN) announced that the U.S. Food and Drug Administration (FDA) has granted approval for Iressa (gefitinib) for the treatment of advanced non-small-cell lung cancer (NSCLC)....

Uteroglobin transduction has an inhibitory effect on lung cancer cell lines.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Uteroglobin transduction has an inhibitory effect on lung cancer cell lines. "Uteroglobin is a secretory protein synthesized by most epithelia, including the respiratory tract. It has strong...

11778 Mutation does not change cellular response to cytotoxic drugs.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- The 11778 mutation does not change cellular response to cytotoxic drugs. According to recent research from the United States, "Leber's hereditary optic neuropathy (LHON) is a bilateral subacute...

Chemotherapy has good results with epidural NHL if diagnosed promptly.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Chemotherapy has good results with epidural NHL if diagnosed promptly. "Spinal cord compression is a rare presentation of non-Hodgkin lymphoma," scientists writing in the journal Pediatric...

HCV infections are detected in many people with primary lymphoma of the liver.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- HCV infections are detected in many people with primary lymphoma of the liver. "Primary lymphoma of the liver (PLL) is rare. In some cases, the hepatic lymphoma has been diagnosed in patients who...

Maintenance regimens directed towards cyclin D1 may inhibit some malignancies.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Maintenance regimens directed towards cyclin D1 may inhibit some malignancies. "Mantle cell lymphoma is a difficult to treat non-Hodgkin's lymphoma (NHL) whose biochemistry is unusually well...

Rituximab given with chemotherapy results in higher rates of complete response.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Rituximab given with chemotherapy results in higher rates of complete response. "The available data on rituximab in combination with chemotherapy confirm that the addition of an independently active...

Enrollment has resumed in phase I glioma study.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Oncolytics Biotech, Inc., (ONCY) announced that enrollment has resumed in the phase I component of its clinical study examining the use of Reolysin in the treatment of recurrent malignant glioma, the...

Doxil induces regression of pleuropulmonary metastases from malignant meningioma.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Doxil induces regression of pleuropulmonary metastases from malignant meningioma. According to a study from Israel, "Metastatic meningioma is a rare disease, which has no effective chemotherapy. ...

Real-time PCR provides for quantitative detection of gastric cancer metastasis.
June 3, 2003... 2003 JUN 3 - (NewsRx.com & NewsRx.net) -- Real-time polymerase chain reaction (PCR) provides for quantitative detection of gastric cancer metastasis. "Histologic examination lacks the sensitivity to detect micrometastases in gastric cancer...