Cancer Weekly articles from June 2002

Cancer Weekly archives from June 2002

Liposomal accumulation expands utility of doxorubicin in brain tumors.(Brief Article)
June 4, 2002... 2002 JUN 4 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - After thorough investigation, scientists now know why liposome-encapsulated doxorubicin extends survival better than free doxorubicin does in rodent brain tumor...

Embolization procedure extends survival in hepatocellular carcinoma.(Brief Article)
June 4, 2002... 2002 JUN 4 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Doctors may be able to offer some chance for extended survival in some patients with unresectable hepatocellular carcinoma, a primary form of liver cancer, by...

Adenovirus-mediated therapy sensitizes tumor cells to etoposide.(Brief Article)
June 4, 2002... 2002 JUN 4 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Murine model studies have demonstrated that adenovirus E1A (Ad-E1A) gene therapy can sensitize Ewing sarcoma cells to etoposide (VP-16) chemotherapy. Ewing...

Low-grade cervical lesions likely to regress spontaneously in adolescent women.(Brief Article)
June 4, 2002... 2002 JUN 4 - (NewsRx.com & NewsRx.net) -- Low-grade dysplasia found on Pap smears is likely to regress spontaneously in adolescent women, a University of California San Francisco (UCSF) study shows Teenage and young adult women who develop...

Tumor volume can predict effectiveness of chemoradiation treatment.
June 4, 2002... 2002 JUN 4 - (NewsRx.com & NewsRx.net) -- Treatment planning for patients with head and neck cancer is based on several factors related to the patient and the size and extent of disease. Staging systems consider the tumor size and extent of...

Serum growth factor a marker for progression in lung cancer.(Brief Article)
June 4, 2002... 2002 JUN 4 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - A new study has predicted the detection of elevated levels of vascular endothelial growth factor (VEGF) may be useful for deciding whether patients with small...

Mayo Clinic researchers develop 'cancer snitch'.(Brief Article)
June 4, 2002... 2002 JUN 4 - (NewsRx.com & NewsRx.net) -- If the treatment of cancer is a war - as declared decades ago - one of the most daunting problems has always been how to develop reliable reconnaissance once behind enemy lines - that is, inside the...

Microenvironment rules angiogenesis in hematological cancer.(Brief Article)
June 4, 2002... 2002 JUN 4 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - A new report lends additional support to increasing evidence of angiogenic mechanisms in acute myeloid leukemia (AML) although previous studies diverge on where...

Cryo-RECAF released for staining of cancer cells in frozen tissue sections.(Brief Article)
June 4, 2002... 2002 JUN 4 - (NewsRx.com & NewsRx.net) -- BioCurex, Inc., (BOCX) is pleased to announce the commercial launch of its second product, based on the novel and proprietary RECAF marker to the market. Cryo-RECAF is a kit designed for single patient...

Dramatic increase in cancer burden expected as U.S. population ages.(Brief Article)(Statistical Data Included)
June 4, 2002... 2002 JUN 4 - (NewsRx.com & NewsRx.net) -- According to the latest Annual Report to the Nation on the Status of Cancer - a yearly update on cancer occurrence and trends in the U.S.-- cancer death rates decreased from 1993 to 1999, and cancer...

Quest Diagnosis offers gene-based cancer tests for bladder and breast cancer.(Brief Article)
June 4, 2002... 2002 JUN 4 - (NewsRx.com & NewsRx.net) -- Quest Diagnostics, Inc., (DGX) has begun offering Abbott Laboratories' Vysis UroVysion DNA Probe Assay, a noninvasive method for monitoring the recurrence of bladder cancer in patients previously...

Jamming cancer's growth signals with precisely targeted drugs shows promise.
June 4, 2002... 2002 JUN 4 - (NewsRx.com & NewsRx.net) -- The first clue that Gloria Caruso's medical long shot might pay off, 2 years into her losing encounter with cancer, was the look she saw one day on her doctors' faces. Usually they were so grim,...

Rabbit liver protein provides clues to improving cancer treatment.(Brief Article)
June 4, 2002... 2002 JUN 4 - (NewsRx.com & NewsRx.net) -- A rabbit liver protein can effectively activate the promising anticancer drug CPT-11, according to scientists at St. Jude Children's Research Hospital in Memphis, Tennessee. This discovery could...

Antigen Express announces patent award, SBIR grant for Ii-suppression platform technology.(Small Business Innovative Research)(Brief Article)
June 4, 2002... 2002 JUN 4 - (NewsRx.com & NewsRx.net) -- Antigen Express, Inc., (AgExp) announced that the U.S. Patent and Trademark Office has issued to AgExp a new patent, U.S. Patent No. 6,368,855, concerning its Ii-Suppression Platform Technology....

New study determines how frequently high-risk patients should have colonoscopies.(Brief Article)
June 4, 2002... 2002 JUN 4 - (NewsRx.com & NewsRx.net) -- Patients with a family history of colon cancer and a personal history of polyps should be screened for colon cancer with a colonoscopy every three years according to a new study presented at the...

Oxaliplatin on fast track review in the U.S.(Brief Article)
June 4, 2002... 2002 JUN 4 - (NewsRx.com & NewsRx.net) -- Sanofi-Synthelabo is conducting a second-line study (EFC 4584) in patients with colorectal cancer who have progressed while on/or within 6 months following treatment with irinotecan in combination with...

COPP chemotherapy may prevent later hematological cancers.(cyclophosphamide, vincristine, procarbazine, and prednisone)(Brief Article)
June 4, 2002... 2002 JUN 4 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - A widely used cytoxin-based chemotherapy regimen for children with Hodgkin disease may help prevent future hematological cancers, according to researchers in...

First Nevada leukemia cluster lawsuit filed.(Brief Article)
June 4, 2002... 2002 JUN 4 - (NewsRx.com & NewsRx.net) -- Fallon, Nevada, children and their families have a new advocate in their fight against leukemia. Alan S. Levin, MD, JD, has filed the first lawsuit regarding the Fallon leukemia cluster, seeking...

Tax protein-induced drug resistance mediated by surprising agent.(Brief Article)
June 4, 2002... 2002 JUN 4 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in Japan have shed new light on the mechanisms of drug resistance conferred by the leukemic Tax protein. Dr. Yoshimune Sakaki and colleagues...

Campath offers new survival hope for patients with advanced B-CLL.(B-cell chronic lymphocytic leukemia)(Brief Article)
June 4, 2002... 2002 JUN 4 - (NewsRx.com & NewsRx.net) -- Life expectancy of heavily pretreated leukemia (B-CLL) patients doubled from 8 to 16 months in the pivotal clinical trial that led to FDA approval of alemtuzumab (Campath), according to lead author...

Lilly, patients hope drug for asbestos-related cancer gains OK.(Brief Article)
June 4, 2002... 2002 JUN 4 - (NewsRx.com & NewsRx.net) -- Eli Lilly and Co. is working with the U.S. Food and Drug Administration to gain fast-track approval of a drug to treat a rare cancer linked to asbestos exposure. If approved, the drug would become...

GD0039 phase II clinical results are positive.(Brief Article)
June 4, 2002... 2002 JUN 4 - (NewsRx.com & NewsRx.net) -- GlycoDesign, Inc., a leading Canadian biopharmaceutical company, announced the release of important data from the first phase II clinical trial for GD0039, the company's lead anticancer drug. The...

First patient enrolled in pivotal phase III study of Oncophage.(Brief Article)
June 4, 2002... 2002 JUN 4 - (NewsRx.com & NewsRx.net) -- Antigenics, Inc., (AGEN) announced that investigators have enrolled the first patient in a pivotal phase III trial of its personalized cancer vaccine Oncophage (HSPPC-96) for the treatment of metastatic...

New radioimmunotherapy drug proves highly effective.(Brief Article)
June 4, 2002... 2002 JUN 4 - (NewsRx.com & NewsRx.net) -- A Mayo Clinic study indicates the first of a new class of drugs involving radioimmunotherapy benefited a significant number of patients with low-grade B cell non-Hodgkin lymphoma who have exhausted...

Squalamine provides significant blockage of VEGF, angiogenesis.(human ovarian cancer cells)
June 4, 2002... 2002 JUN 4 - (NewsRx.com & NewsRx.net) -- Genaera Corporation (GENR) announced a publication evaluating the potential of squalamine, its antiangiogenic agent, in the treatment of ovarian cancer. The article entitled, "Squalamine and cisplatin...

Women at highest risk less likely to be screened than those at lower risk.(Brief Article)(Statistical Data Included)
June 4, 2002... 2002 JUN 4 - (NewsRx.com & NewsRx.net) -- Women at highest risk for ovarian cancer receive less screening and report less worry about getting the disease than women with a lower yet somewhat elevated risk, according to researchers at the Fred...

Elkhart General Hospital performs intensity modulated radiation therapy.(Brief Article)
June 4, 2002... 2002 JUN 4 - (NewsRx.com & NewsRx.net) -- Elkhart General Hospital is the most recent oncology center in the United States to use MDS Nordion's Dose Calculated Module (DCM) to perform an Intensity Modulated Radiation Therapy (IMRT) clinical...

Phase I/II clinical trial of CpG 7909 initiated.(Brief Article)
June 4, 2002... 2002 JUN 4 - (NewsRx.com & NewsRx.net) -- Coley Pharmaceutical Group, Inc., announced that it has initiated a multicenter open label, phase I/II clinical trial of its lead product candidate, CpG 7909, for the treatment of patients with stage IV...

INEX releases interim data from Onco TCS clinical trial.(Inex Pharmaceuticals Corp.)(Brief Article)
June 4, 2002... 2002 JUN 4 - (NewsRx.com & NewsRx.net) -- Inex Pharmaceuticals Corporation announced interim results from a phase II human clinical trial that showed the company's lead product, Onco TCS, has activity in treating patients with small cell lung...

Suppressing MDM2 gene reduces tumor mass in soft tissue sarcoma.(Brief Article)
June 11, 2002... 2002 JUN 11 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - The MDM2 oncogene is a p53 tumor suppressor gene antagonist. Halting MDM2 protein expression in soft tissue sarcomas with antisense gene therapy causes those...

Agent an active cancer fighter in patients with relapsed multiple myeloma.(Brief Article)
June 11, 2002... 2002 JUN 11 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - The results of an Italian study have shown the antiangiogenic drug thalidomide could be an important cancer fighter in patients with relapsed multiple myeloma....

Freezing cancer cells makes them prime targets for anticancer drug, new study finds.(Brief Article)
June 11, 2002... 2002 JUN 11 - (NewsRx.com & NewsRx.net) -- The answer to improving the effectiveness of certain cancer treatments may be in stopping the malignant cells cold. Two researchers from the Institut Gustave-Roussy in France and the University of...

Researchers uncover biochemical connection to high-fat diets.(Brief Article)
June 11, 2002... 2002 JUN 11 - (NewsRx.com & NewsRx.net) -- Researchers at the University of Texas (UT) Southwestern Medical Center at Dallas have uncovered what could be a key clue in tracing the connection between high-fat diets and increased colon cancer...

Encapsulated vaccine more effective than vaccine suspensions for reducing tumor burden.(Brief Article)
June 11, 2002... 2002 JUN 11 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - When used preoperatively or early postoperatively for murine colorectal cancer, an encapsulated whole-cell plus adjuvant vaccine significantly...

Alcohol may hasten the progression of cancer.
June 11, 2002... 2002 JUN 11 - (NewsRx.com & NewsRx.net) -- Alcohol, the socially acceptable drug, acts upon virtually every organ system and causes a variety of physiologic and behavioral alterations. Its ability to compromise the body's immune system has...

Reduced-intensity stem cell transplant conditioning regimen effective.(Brief Article)
June 11, 2002... 2002 JUN 11 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in Japan say that a reduced-intensity, cladrabine-based conditioning regimen can improve outcomes for leukemia and lymphoma patients undergoing...

Prolactin proactive in promoting breast cancer.(Brief Article)
June 11, 2002... 2002 JUN 11 - (NewsRx.com & NewsRx.net) -- In the pursuit of novel cancer therapies, researchers at the University of Pennsylvania School of Medicine describe new mechanisms by which the hormone prolactin induces the growth and spread of breast...

Dramatic increase in cancer burden predicted as U.S. population ages.(Brief Article)(Statistical Data Included)
June 11, 2002... 2002 JUN 11 - (NewsRx.com & NewsRx.net) -- According to the latest "Annual Report to the Nation on the Status of Cancer" - a yearly update on cancer occurrence and trends in the U.S.- cancer death rates decreased from 1993 to 1999, and cancer...

Targeted vaccine may help immune system fight cancer.
June 11, 2002... 2002 JUN 11 - (NewsRx.com & NewsRx.net) -- Completing an important step in the evaluation of a cancer vaccine that has the potential to selectively target a wide range of tumors, researchers at the Ludwig Institute for Cancer Research report...

New tests planned.(computer tomography colonoscopy)(Brief Article)
June 11, 2002... 2002 JUN 11 - (NewsRx.com & NewsRx.net) -- The radiologist peers into Pauline Morse's colon, pausing to inspect a fleshy fold before moving deeper into the shadowy twists and turns. But Morse, 73, isn't lying on a table during this intimate...

Mayo Clinic helps determine best screening method.(colorectal cancer)(Brief Article)
June 11, 2002... 2002 JUN 11 - (NewsRx.com & NewsRx.net) -- Colorectal cancer is the second highest cause of cancer-related deaths in the United States. Regular testing to detect and remove colorectal polyps, however, can prevent colorectal cancer. It...

Jefferson scientists create first animal model of common type of leukemia.(Jefferson Medical College, Kimmel Cancer Center at Thomas Jefferson University)(Brief Article)
June 11, 2002... 2002 JUN 11 - (NewsRx.com & NewsRx.net) -- Researchers at Jefferson Medical College and the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia have developed the first animal model of the most common type of human leukemia. ...

Patients with advanced B-CLL double life expectancy in clinical trial.(B cell chronic lymphocytic leukemia)(Brief Article)
June 11, 2002... 2002 JUN 11 - (NewsRx.com & NewsRx.net) -- Life expectancy for patients with B cell chronic lymphocytic leukemia (B-CLL) doubled from eight to 16 months in a worldwide clinical trial of alemtuzumab (CampathR), according to lead researcher Dr....

New treatment reduces tumors and improves quality of life for patients.(Brief Article)
June 11, 2002... 2002 JUN 11 - (NewsRx.com & NewsRx.net) -- A new treatment option for inoperable primary liver cancer called TheraSphere appears to be safe and effective for liver cancer patients, according to results presented by a University of Pittsburgh...

Data presented on cetuximab combined with docetaxel.(Brief Article)
June 11, 2002... 2002 JUN 11 - (NewsRx.com & NewsRx.net) -- ImClone Systems Inc. (IMCL) and Bristol-Myers Squibb (BMY) announced data from a study of the investigational monoclonal antibody Erbitux (cetuximab) in combination with docetaxel. Data showed the...

New experimental pill found to improve symptoms and quality of life.(Brief Article)
June 11, 2002... 2002 JUN 11 - (NewsRx.com & NewsRx.net) -- An experimental pill has been found to improve symptoms and quality of life in patients with non-small-cell lung cancer, according to research findings presented by Ronald B. Natale, MD, acting medical...

Genetic discovery in fruit flies may open new avenues for understanding cancer growth in humans.
June 11, 2002... 2002 JUN 11 - (NewsRx.com & NewsRx.net) -- Fred Hutchinson Cancer Research Center scientists report a finding in the common fruit fly that may open new paths for understanding some of the key genetic missteps that lead to cancer in humans. The...

Study finds inherited genetic factor may not extend ovarian cancer patient's survival.(Brief Article)
June 11, 2002... 2002 JUN 11 - (NewsRx.com & NewsRx.net) -- A University of Iowa (UI) Health Care investigation has found that, contrary to some reports, women with inherited ovarian cancer may not have a better survival prognosis than women with ovarian cancer...

Escalating incidence of childhood cancer is ignored.(Brief Article)(Statistical Data Included)
June 11, 2002... 2002 JUN 11 - (NewsRx.com & NewsRx.net) -- The following was released by Samuel S. Epstein, MD, chairman of the Cancer Prevention Coalition and professor emeritus of environmental and occupational medicine, University of Illinois School of...

Long-term survival data in phase II trial of GVAX vaccine reported at conference.(Brief Article)
June 11, 2002... 2002 JUN 11 - (NewsRx.com & NewsRx.net) -- Cell Genesys, Inc. (CEGE) has reported encouraging long-term survival data from a phase II multicenter clinical trial of GVAX prostate cancer vaccine which demonstrates a dose-dependent trend toward...

Molecularly targeted drug slows tumor growth in patients.(Brief Article)
June 11, 2002... 2002 JUN 11 - (NewsRx.com & NewsRx.net) -- Researchers from the National Cancer Institute (NCI) have reported that the molecularly targeted drug bevacizumab slowed tumor growth in patients with metastatic renal cell carcinoma, the most common...

Positive selection effective for autologous grafts from neuroblastoma patients.(Brief Article)
June 11, 2002... 2002 JUN 11 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Positive selection is a suitable purging technique for use with autologous stem cell grafts taken from children suffering from neuroblastoma, researchers say....

Stem cell transplantation feasible after arsenic trioxide therapy.(Brief Article)
June 18, 2002... 2002 JUN 18 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Hematopoietic stem cell transplantation is feasible for acute promyelocytic leukemia patients treated with arsenic trioxide, researchers in Italy report. ...

VP22-mediated trafficking leads to heightened apoptosis in liver cancer.(Brief Article)
June 18, 2002... 2002 JUN 18 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - VP22-mediated trafficking can enhance p53 protein expression in primary liver cancer cells. The results of a study that was conducted in Germany has...

Test predicts if chemotherapy will work.(Brief Article)
June 18, 2002... 2002 JUN 18 - (NewsRx.com & NewsRx.net) -- Resistance to chemotherapy is a major cause of treatment failure in patients with breast cancer. A study reported in the June 2002 issue of the Journal of Nuclear Medicine found that scintigraphic...

New diagnostic fecal test could identify colorectal cancer.(Brief Article)
June 18, 2002... 2002 JUN 18 - (NewsRx.com & NewsRx.net) -- Authors of a research letter in the June 1, 2002, issue of the Lancet describe a new technique where the detection of a specific protein in feces could be a marker for colorectal cancer. ...

Oxygen deprivation accounts for pathways leading to vascular invasion.(Brief Article)
June 18, 2002... 2002 JUN 18 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Cell culture experiments have demonstrated that hypoxia leads to connective tissue growth factor production, facilitating matrix degradation, angiogenesis, and...

Fiber modification enables viral vectors to skirt receptor deficiency.(Brief Article)
June 18, 2002... 2002 JUN 18 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Medical investigators have discovered that fiber modification enables adenoviral vectors to transfer genes to ovarian cancer cells effectively despite variable...

UF physicians report new treatment helps some cancer patients avoid major surgery.(University of Florida )(Brief Article)
June 18, 2002... 2002 JUN 18 - (NewsRx.com & NewsRx.net) -- A high-fat, low-fiber diet is a nutritionist's nightmare for good reason: It predisposes people to a host of troublesome medical problems, rectal cancer among them. Each year, thousands develop the...

Antiretroviral therapy improves survival.(Brief Article)
June 18, 2002... 2002 JUN 18 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Potent antiretroviral therapy improves outcomes for patients suffering from malignancies associated with HIV infection, researchers in the United States...

Tetra-arsenic tetra-sulfide safe, effective.(Brief Article)
June 18, 2002... 2002 JUN 18 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Tetra-arsenic tetra-sulfide (As[subscript]4S[subscript]4) shows promise for the treatment of patients suffering from acute promyelocytic leukemia (APL),...

Cancer-suppressing protein is part of ameba's compass.(Protein: PTEN)(Brief Article)
June 18, 2002... 2002 JUN 18 - (NewsRx.com & NewsRx.net) -- Researchers from the Johns Hopkins School of Medicine have learned that a protein that prevents the formation of cancerous tumors in animals also helps single-cell ameba determine direction,...

Growth factor indicative of response to radiotherapy in female cancers.(Brief Article)
June 18, 2002... 2002 JUN 18 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Doctors in Vienna, Austria, report serum levels of a single growth factor could be used to predict which women with cervical cancer might respond to treatment...

Study suggests SuperGen's Orathecin is also effective against certain advanced bone tumors.(Brief Article)
June 18, 2002... 2002 JUN 18 - (NewsRx.com & NewsRx.net) -- SuperGen, Inc., (SUPG) reported data from an ongoing phase II clinical study that suggest the company's anticancer compound Orathecin is effective against chordoma, a rare type of bone tumor. Results...

CLA may help to inhibit proliferation of colon, prostate cancer, study suggests.(Brief Article)
June 18, 2002... 2002 JUN 18 - (NewsRx.com & NewsRx.net) -- In a study published in Cancer Letters, researchers at Harvard Medical School have identified molecular components in the dietary supplement conjugated linoleic acid (CLA) as potentially influential in...

New treatment holds promise of helping patients with advanced disease live longer.(FOLFOX: chemotherapy using oxaliplatin, investigational drug in clinical trials)(Brief Article)
June 18, 2002... 2002 JUN 18 - (NewsRx.com & NewsRx.net) -- Patients with advanced colorectal cancer who received FOLFOX, a chemotherapy regimen containing the investigational drug oxaliplatin, responded significantly better to treatment, had fewer severe side...

Study determines how frequently high-risk patients should be screened.(Brief Article)
June 18, 2002... 2002 JUN 18 - (NewsRx.com & NewsRx.net) -- Patients with a family history of colon cancer and a personal history of polyps should be screened for colon cancer with a colonoscopy every 3 years, according to a new study presented at the American...

Celebrated idea for curing cancer proves hard to translate from mouse to man.(Brief Article)
June 18, 2002... 2002 JUN 18 - (NewsRx.com & NewsRx.net) -- Dr. Judah Folkman's mice are growing old and gray, famously cured of cancer. But people? Not yet and probably not real soon. Developing new cancer treatments is a notoriously frustrating...

GI cancer patients still responding to Gleevec after 1 year follow-up.(Brief Article)
June 18, 2002... 2002 JUN 18 - (NewsRx.com & NewsRx.net) -- New data demonstrate that more than 60% of patients with an inoperable and life-threatening form of gastrointestinal cancer (gastrointestinal stromal tumors, or GISTs) are continuing to respond to the...

Phase II trial of squalamine shows encouraging results.(Brief Article)
June 18, 2002... 2002 JUN 18 - (NewsRx.com & NewsRx.net) -- Genaera Corporation (GENR) announced the presentation of encouraging results for its antiangiogenic drug, squalamine, in its phase II recurrent advanced ovarian cancer clinical trial, at the meeting of...

Atrasentan (ABT-627) offers hope to patients with metatastic prostate cancer.(Brief Article)
June 18, 2002... 2002 JUN 18 - (NewsRx.com & NewsRx.net) -- New phase II data presented at the American Society of Clinical Oncology (ASCO) annual meeting show that treatment with atrasentan Abbott Laboratories' investigational, selective endothelin-A receptor...

Columbia study finds differences in PSA, PSA density test measurements for Caucasian, Hispanic men.(Brief Article)
June 18, 2002... 2002 JUN 18 - (NewsRx.com & NewsRx.net) -- Doctors at New York-Presbyterian Hospital's Columbia Presbyterian campus have reported the results of one of the few studies to look at the performance of prostate-specific antigen (PSA) tests in the...

Complexed PSA test more accurate than traditional PSA test in detecting prostate cancer.(Brief Article)
June 18, 2002... 2002 JUN 18 - (NewsRx.com & NewsRx.net) -- Findings released May 25, 2002, conclude that the complexed prostate specific antigen (cPSA) test is more accurate than the total PSA (tPSA) test currently used by most physicians for prostate cancer...

EntreMed's Panzem shows activity in advanced prostate cancer.(Brief Article)
June 18, 2002... 2002 JUN 18 - (NewsRx.com & NewsRx.net) -- EntreMed, Inc. (ENMD), a biopharmaceutical leader in angiogenesis research and product development, presented clinical evidence that its drug candidate Panzem demonstrated anticancer activity with...

Study shows cancer cells are vulnerable in new ways.(Brief Article)
June 18, 2002... 2002 JUN 18 - (NewsRx.com & NewsRx.net) -- Vitamin E, a compound suspected of playing a role in preventing prostate cancer, interferes with two proteins that play a central role in the development of the disease. This is the report of...

Zometa effective for debilitating bone complications.(Brief Article)
June 18, 2002... 2002 JUN 18 - (NewsRx.com & NewsRx.net) -- The Novartis drug Zometa (zoledronic acid for injection) is effective for the treatment of potentially debilitating skeletal related events from bone metastases in prostate cancer patients, according...

EPA study concludes toxic chemicals are cancer risk.(Brief Article)
June 18, 2002... 2002 JUN 18 - (NewsRx.com & NewsRx.net) -- Toxic chemicals pose an elevated cancer risk to two-thirds of Americans living in nearly every part of the country, said an assessment by the Environmental Protection Agency (EPA). A long-awaited...

Growth factor expression in airway may mark extent of lung cancer.(Brief Article)
June 25, 2002... 2002 JUN 25 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Identifying expression levels of a key angiogenic growth factor in the airways of patients with lung cancer could be valuable for assessing their progression...

Macrophage expression of interleukin-8 related to uterine tumor invasion.(Brief Article)
June 25, 2002... 2002 JUN 25 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Physicians in Japan are certain that macrophage-produced interleukin-8 is related to angiogenesis and invasion in uterine endometrial cancer in women. ...

Genetic mutation plays major role.(Brief Article)
June 25, 2002... 2002 JUN 25 - (NewsRx.com & NewsRx.net) -- New research suggests inherited genetic mutations play a larger role than previously thought in the development of a rare form of adrenal cancer - findings that offer important implications for...

Interferon-(beta) a multitasking cancer killer.(Brief Article)
June 25, 2002... 2002 JUN 25 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Interferon-(beta) gene therapy suppresses bladder cancer invasion and metastasis via at least two major mechanisms, scientists at a major research center have...

High levels of sex hormones doubles risk in postmenopausal women.(Brief Article)
June 25, 2002... 2002 JUN 25 - (NewsRx.com & NewsRx.net) -- Postmenopausal women with relatively high serum concentrations of estrogen and testosterone have about twice the risk of developing breast cancer as women with relatively low serum concentrations of...

Malignant cells can express immunosuppressive enzyme.(Brief Article)
June 25, 2002... 2002 JUN 25 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in Australia have shed new light on the ability of cancer cells to avoid detection by immune processes. "The mechanisms by which tumor cells...

UCSF finding offers provocative insight into what drives cancer.(Brief Article)
June 25, 2002... 2002 JUN 25 - (NewsRx.com & NewsRx.net) -- In a finding that calls into question a prevailing belief about the way in which cancers develop and progress, researchers led by a University of California San Francisco (UCSF) scientist report that...