Cancer Weekly articles from July 2004

Cancer Weekly archives from July 2004

Ascorbic acid makes cancer cells insensitive to chemotherapy.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Ascorbic acid makes cancer cells insensitive to chemotherapy. "Although a high alimentary intake of antioxidant vitamins such as ascorbic acid may play an important role in cancer prevention, a...

Cell density affects the cytotoxicity of daunorubicin and cytosine arabinoside.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Cell density affects the cytotoxicity of daunorubicin and cytosine arabinoside. "White blood cell count (WBC) is generally accepted as a prognostic risk factor in acute myeloid leukemia (AML)...

Hematopoietic growth factors manage the effects of non-Hodgkin lymphoma therapy.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Hematopoietic growth factors manage the effects of non-Hodgkin lymphoma therapy. "Combination chemotherapy used to treat patients with aggressive non-Hodgkin lymphoma is associated with neutropenia...

Thrombospondin 1 bears fragments that counteract its antiangiogenic potential.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Thrombospondin 1 bears fragments that counteract its antiangiogenic potential. "Gliomas are among the most malignant and most highly vascularized human tumors. We studied the therapeutic action of...

HIM-prostate brachytherapy performs well in the community setting.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- HIM-prostate brachytherapy performs well in the community setting. According to published research from the United States, "the aim of this study is to evaluate the target coverage, procedural...

Surgical interdisciplinarity is needed for abdominal surgery.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Interdisciplinary cooperation between surgical specialties is necessary for optimal treatment outcome, researchers say. According to a study from Germany, "Cooperation between different surgical...

Hypoxia inducible factor cultivates the angiogenic landscape of leukemia.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Hypoxia inducible factor cultivates the angiogenic landscape of leukemia. According to a study from Germany, "hypoxia-inducible factor 1 (HIF-1) controls angiogenesis and glycolysis, two leading...

An in vivo model reveals elements underlying angiogenesis in obesity.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- An in vivo model reveals elements underlying angiogenesis in obesity. "Obesity is associated with an increased risk for cardiovascular disease and cancer. Angiogenesis is a critical component of...

Tocosol Paclitaxel shows anti-tumor activity in advanced cancer, well tolerated.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Sonus Pharmaceuticals, Inc., (SNUS) presented ongoing results from three phase IIa clinical studies of Tocosol Paclitaxel in poster sessions during the Annual Meeting of the American Society of Clinical...

Study evaluates Xcytrin plus Taxotere for advanced refractory tumors.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Pharmacyclics, Inc., (PCYC) announced encouraging early findings from a phase I clinical trial of Xcytrin (motexafin gadolinium) Injection, the company's lead cancer therapeutic candidate, in...

Decitabine well tolerated with chemotherapy for advanced solid tumors.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- SuperGen, Inc., (SUPG) announced that a phase I study of Dacogen (decitabine) for injection, the company's investigational cancer treatment for myelodysplastic syndromes (MDS), demonstrated positive...

Positive preliminary results announced for VEGF Trap study in solid tumors.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Regeneron Pharmaceuticals, Inc., (REGN) announced positive preliminary results from the phase I trial for the company's vascular endothelial growth factor (VEGF) Trap in patients with advanced solid...

Pemirolast is a potent reliever of paclitaxel-induced allergic reactions.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Pemirolast is a potent reliever of paclitaxel-induced allergic reactions. According to recent research published in the journal Neuropharmacology, "the effects of anti-allergic agents on the...

Positive ACAPODENE data presented at ASCO meeting.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- GTx, Inc., (GTXI), a biopharmaceutical company dedicated to the discovery, development, and commercialization of therapeutics primarily related to the treatment of serious men's health conditions,...

Studies: Aranesp dosed semiweekly is comparable to epoetin alfa once a week.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Amgen, Inc., (AMGN) presented final results from an analysis of three identical head-to-head trials showing that Aranesp (darbepoetin alfa) dosed once every 2 weeks provided similar results as epoetin...

Aranesp corrects chemotherapy-induced anemia when dosed once every 3 weeks.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Amgen Inc. (AMGN) announced results of a new study demonstrating that Aranesp (darbepoetin alfa) dosed once every 3 weeks achieved and maintained the target hemoglobin levels recommended by clinical...

Angiostatin reduces retinal vascular leakage in rodent models.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Angiostatin reduces retinal vascular leakage in rodent models. "Angiostatin is a potent angiogenic inhibitor. The present study identified a new activity of angiostatin: reducing vascular leakage,...

Laparoscopy improves the study of metastatic liver tumors in rodent models.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Laparoscopy improves the study of metastatic liver tumors in rodent models. According to a study from Denmark, "metastatic disease to the liver is one of the major factors determining the outcome of...

MediciNova acquires phase II anxiety compound.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- MediciNova, Inc., a privately held specialty pharmaceutical company, announced the acquisition of a potential treatment for anxiety disorders from Mitsubishi Pharma Corp. of Japan. The compound,...

Study finds cancer drug appears highly effective against arthritis.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- For the first time, a drug has relieved rheumatoid arthritis by knocking out a certain type of immune cell, an approach that could open the way for precisely targeted, "smart" treatments for the joint...

Five cancer researchers win Spanish science prize.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Five leading cancer researchers, a Briton, a Spaniard and three Americans, jointly won a prestigious Spanish prize for science on June 16, 2004. "From their different lines of investigation these...

US Oncology-affiliated practices win ASCO Clinical Trials Participation Award.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- The American Society of Clinical Oncology (ASCO) has named two practices affiliated with US Oncology winners of its Clinical Trials Participation Award. Texas Oncology, P.A.-Tyler and Virginia...

Bacteria LPS induce IL-6-dependent plasmacytoma proliferation.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Bacterial lipopolysaccharides induce IL-6-dependent plasmacytoma proliferation by MAPK pathway activation. According to published research from Bulgaria, "Mouse plasmacytomas are appropriate models...

Patients with chronic ulcers and erosions should be screened for MRSA.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Patients with chronic ulcers and erosions should be screened for MRSA. According to a study from Germany, "The prevalence of methicillin-resistant Staphylococcus aureus (MRSA) was prospectively...

Polymers promote heparin uptake and cancer cell apoptosis.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Polymers promote heparin uptake and cancer cell apoptosis. "Heparin/heparan sulfate-like glycosaminoglycans (HSGAGs) are involved in diverse cellular processes in the extracellular matrix (ECM)....

Carrier-added tracers highlight bone lesions during bone scans.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Carrier-added tracers highlight bone lesions during bone scans. According to recent research published in the journal Nuclear Medicine Communications, "an increased uptake of bone-seeking...

Positive data presented on IRHs and bone-marrow protection.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Hollis-Eden Pharmaceuticals, Inc., (HEPH) announced results from a presentation given at the American Society of Clinical Oncology (ASCO) meeting demonstrating positive results with investigational...

Bone metastasis is an infrequent first sign solid tumor spread.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Excluding prostate tumors, bone metastases is not a common indicator of the first sign of metastatic spread in solid tumor patients. In a retrospective study, published in the journal International...

Quality of life in long-term survivors of pediatric brain stem tumors can suffer.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Researchers find that long-term survivors of brain stem tumors during childhood may have neurological impairments. "The quality of life in long-term survivors of pediatric brain stem tumors treated...

Age at diagnosis reflects disease stage and subsequent quality of care.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Start those breast exams early, U.K. oncologists say, because older women presenting with breast cancer tend to have more advanced disease, worse prognosis, and less comprehensive care. "Breast...

Better care has reduced breast cancer mortality in Italy.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Screening and improved care have lowered breast cancer mortality rates in Florence, Italy. "We compared breast cancer mortality rates in the period 1985-2000 in two areas of the province of...

Blood test detects genetic changes in progressive disease.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Researchers at the University of Texas Southwestern Medical Center at Dallas have developed a blood test that can detect amplification of a certain gene found in circulating cells associated with breast...

Bonefos increases survival in primary operable breast cancer patients.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Data presented at the 40th Annual American Society of Clinical Oncology Meeting showed that oral clodronate (Bonefos), when administered daily for 2 years, decreased the incidence of bone metastases and...

Breast surgery and radiotherapy affect arm, shoulder mobility and strength.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Study finds that patients treated with modified radical mastectomy and radiotherapy as well as patients not irradiated have deficits in some arm and shoulder motions and strength. According to a...

Counseling improves women's functioning.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Counseling helps women cope with their risk of breast cancer. According to a study from the United States, "Helping people cope with health risks is an important area for research and practice....

ER- breast cancer cell ERa re-expression recreate hormone-responsive phenotype.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Estrogen receptor negative breast cancer cell ERalpha re-expression recreate a hormone-responsive phenotype. "Estrogen receptor (ER)-negative breast carcinomas are often difficult to treat with...

Encouraging results for Oncotype DX assay in predicting chemotherapy response.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Genomic Health, Inc., and Istituto Nazionale Tumori, a cancer-research institute located in Milan, Italy, announced preliminary results of a clinical trial in which the patterns of expression of a...

Gemzar/Taxol vs Taxol alone improves survival in breast cancer study patients.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- New interim data show that metastatic breast cancer patients experienced a promising improvement in survival when treated with a Gemzar/Taxol combination compared to patients treated with Taxol alone, a...

Multiple mRNA markers detect metastases in sentinel lymph nodes.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Multiple mRNA markers detect metastases in the sentinel lymph nodes of breast cancer patients. "Disseminated breast tumor cells in sentinel lymph nodes (SNs) were evaluated by quantitative real-time...

New prognostic markers for survival of breast cancer identified.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- New prognostic markers for survival of breast cancer have been identified. According to a study from England, "The normal duct-lobular system of the breast is lined by two epithelial cell types,...

New tumor subtypes with poor clinical outcomes characterized.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- A University of North Carolina (UNC) molecular biologist has identified the pattern of genes that characterize a biologically distinct subtype of estrogen receptor negative breast tumor. Because...

Oncogenic marker is a powerful prognostic tool.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- The P70 S6 kinase protein (PS6K) predicts poor locoregional control and may have clinical value in choosing a strategy in breast care patients, according to a study from The Netherlands. "The...

Pharmacogenomics discussed at meeting as personalized breast cancer treatment.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Attendees at the 40th annual meeting of the American Society of Clinical Oncologists (ASCO) learned more about pharmacogenomics, an emerging field of research that aims to individualize cancer treatment...

Raloxifene, exemestane may provide postmenopausal breast cancer risk reduction.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Attendees at the 40th annual meeting of the Association of Clinical Oncologists were updated on the serum estrogen receptor modulator (SERM) raloxifene and the aromatase inhibitor (AI) exemestane, with...

Results reported in trial of Abraxane for advanced breast cancer patients.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Abraxis Oncology, a division of American Pharmaceutical Partners, Inc., (APP, APPX) said that results from a 106 patient phase II study of Abraxane in patients with advanced breast cancer whose disease...

Several parallel and stepwise progression pathways towards breast cancer.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- There are several parallel and stepwise progression pathways towards breast cancer. "Distinct parallel cytogenetic pathways in breast carcinogenesis could be identified in recent years....

Significant survival advantage reported in phase III trial of Theratope.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Biomira, Inc., (BIOM, BRA) of Edmonton, Alberta, Canada, announced that an exploratory analysis showed a statistically significant survival advantage for women in the hormonal therapy subset of patients...

Study investigates resistance to tamoxifen and possible way to reverse it.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- A new study has found a possible mechanism for tamoxifen resistance in breast cancer and provides evidence that another cancer drug - gefitinib (AstraZeneca brand name: Iressa) - may be able to restore...

Study offers new target to stop cancer growth.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Two proteins that normally help cells move from place to place and are made in large quantities in breast cancer cells work together to promote the survival and spread of breast cancer, according to a...

Three SenoScan systems to be installed at California-based breast center.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Fischer Imaging Corporation (FIMG) is installing three SenoScan systems and two physician review workstations at the Avon Foundation Comprehensive Breast Center at San Francisco General Hospital in...

Three novel hormone-responsive cell lines expand research armory.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Researchers in Argentina are pursuing study of three novel cell lines that look promising as tools for examining breast cancer in vitro. "Human breast cancer primary cultures are useful tools for...

Variations in estrogen metabolism genes don't affect disease risk.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- A new study shows that common mutations in genes that regulate estrogen metabolism are not associated with breast cancer risk. Several studies have suggested that circulating levels of sex...

Widely reported cognitive side effect of chemotherapy may be overestimated.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- A new study says the incidence of "chemobrain," a widely reported side effect in women undergoing treatment for breast cancer, may be overestimated. Researchers found significant deficits in...

Data regarding intraoperative radiotherapy for early breast cancer is unclear.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Data regarding intraoperative radiotherapy for early breast cancer is unclear. According to a study from Australia, "a systematic review was undertaken to assess the safety and efficacy of...

VEGF-DT385 toxin conjugate prevents mammary adenocarcinomas in transgenic mice.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- VEGF-DT385 toxin conjugate prevents mammary adenocarcinomas in transgenic mice. According to published research from the United States, "previous experiments have shown that a vascular endothelial...

Implant salvage is possible, but removal and delayed reinsertion is more likely.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Infection and device extrusion can lead to the need for breast implant salvage, although removal and delayed reinsertion is a more likely option, study data indicate. "Among the potential...

Results of AVR118 phase I/II clinical program presented at ASCO.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Advanced Viral Research Corp. (ADVR) announced that the company presented interim results of its phase I/II clinical program with its flagship product, AVR118, at The American Society of Clinical...

More Georgians learn about cancer through campaign.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- "Every woman deserves to be healthy," poet Maya Angelou says in her smooth voice during a radio ad that encourages mammograms. A child dressed as a bee urges people in a TV commercial to get...

Device firm reaches agreement with FDA on trial of ComfortScan system.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Dobi Medical International, Inc., (DBMI) announced that it has reached agreement with the U.S. Food and Drug Administration (FDA) regarding the clinical study the company will conduct as its final step...

Near-infrared imaging detects HER-2 overexpression by tumor cells.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Near-infrared flourescence imaging can be used to detect HER-2 overexpression by tumor cells. Radiologists in Germany conducted a study "to evaluate in vitro and in vivo imaging of...

Pediatric chest tube useful for bone marrow specimen collection.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- A novel system can facilitate collection of diagnostic samples from patients with bone malignancies. Researchers in North Carolina devised "a simple technique of bone marrow specimen collection of...

Skin cancer registries in the United Kingdom have room for improvement.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Skin cancer registries in the United Kingdom have room for improvement. According to a study from Wales, "cancer registries are used to compare incidences between regions, plan for service...

Interleukin-12 arrests canine hemangiosarcoma growth in murine xenografts.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Interleukin-12 arrests canine hemangiosarcoma growth in canine xenografts. "We established a canine hemangiosarcoma cell line derived from malignant endothelial cells comprising a spontaneous tumor...

Risk assessments support a link between previous PAH exposures and lung cancer.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Risk assessments support a link between previous PAH exposures and lung cancer. According to researchers in Canada, "we assessed the lung cancer risk in six localities with aluminium smelting...

The American Cancer Society launches Team ACS web site.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- The American Cancer Society launched a new Web site, http://www.cancer.org/TeamACS. The site allows participants of fun runs, triathlons, bike races, marathons, and other events to support the fight...

B-cell, T-cell, and Hodgkin lymphomas have different lung infiltration patterns.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- B-cell, T-cell, and Hodgkin lymphomas have different lung infiltration patterns. "Secondary lung infiltration by lymphomas occurs frequently. To our knowledge, however, no recent studies have...

Cancer research effort nets $350,000 from lemonade stands.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Alex's Lemonade Stand, the charity started by a young cancer patient to benefit cancer research, tallied $350,000 in donations as of June 14, 2004, from lemonade fund-raisers held nationwide over the...

Upstate awarded $207K grant from National Cancer Institute.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Upstate, in collaboration with the University of Virginia Health Science Center, has been granted a phase I STTR (Small Business Technology Transfer) award in the amount of $207,522 by The National...

A model for analyzing risks of groundwater contamination is developed.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Researchers develop a method for analyzing cancer risk associated with waste landfill sites. "An integrated simulation-assessment modeling approach for analyzing environmental risks of groundwater...

Arsenic in drinking water in Bangladesh increases risk of some cancer.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Drinking water in Bangladesh has high levels of contaminated with arsenic, which can double the lifetime mortality risk for some cancers. According to recent research from the United States, "We...

Cancer among siblings but not parents may have a recessive cause.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- The risk of siblings developing renal cancer is especially high, researchers find. According to a study from Sweden, "Occurrence of cancer in parents and offspring may be due to dominant causes,...

Low-fat and low-energy diets have small effect on oxidative DNA damage.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Research reveals that low-fat and low-energy diets have only a small effect on oxidative DNA damage levels. "Oxidative DNA damage in blood appears to be useful as a marker of systemic oxidative...

Cancer prevention programs that consider psychosocial factors make an impact.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Cancer prevention programs that consider psychosocial factors make an impact. "The European Code against Cancer includes some primary cancer prevention behaviors, which can be studied in the...

Prepubertal estrogenic exposures may reduce breast cancer risk later on.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Prepubertal estrogenic exposures may reduce breast cancer risk later on. "Prepubertal exposure to soy or its biologically active component genistein reduces later breast cancer risk in both animal...

Researchers continue to explore the action of phytoestrogens against cancer.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Phytoestrogens guard against hormone-dependent cancers and researchers continue to explore their mechanisms of action. According to a study from Northern Ireland, "The incidence of...

Cloned transgenic animals produce high levels of antitumor bispecific antibody.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Cloned transgenic animals can produce high levels of a bispecific antitumor antibody "Complex recombinant antibody fragments for modulation of immune function such as tumor cell destruction have...

Company initiates phase II corporate clinical program for KRX-0401 (Perifosine).
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Keryx Biopharmaceuticals, Inc., (KERX) announced the initiation of a corporate-sponsored clinical program for KRX-0401 (Perifosine), a novel, oral, AKT inhibitor for the treatment of cancer. In...

Company summarizes survival benefits in key patient subsets from BR.21 study.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- OSI Pharmaceuticals, Inc., (OSIP) announced that a summary of data presented at the 40th annual meeting of the American Society of Clinical Oncology (ASCO) summarizing the treatment benefit observed in...

Data: Onco TCS has potential in first-line lymphoma.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Inex Pharmaceuticals Corp. (IEX) and Enzon Pharmaceuticals, Inc., (ENZN) released follow-up results from a phase II clinical trial that indicate Onco TCS (vincristine sulfate liposomes injection) has...

FDA grants fast track designation for MedPulser Electroporation Therapy System.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Genetronics Biomedical Corp. (GEB) has been granted a fast track designation by the U.S. Food and Drug Administration for its MedPulser Electroporation System clinical development program for patients...

Genotyping helps determine appropriate Quinamed dose in cancer study patients.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Results of a phase I/II trial that used patient genotyping to determine dosing of Quinamed (amonafide dihydrochloride), an experimental cancer drug under development by ChemGenex Therapeutics, were...

Key Herceptin data presented at ASCO meeting.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Genentech, Inc., (DNA) announced updated results from a phase III study evaluating Herceptin (Trastuzumab) in combination with paclitaxel and carboplatin, as well as a retrospective analysis of the...

Lapatinib shows antitumor activity in herceptin-resistant breast cancer patients.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- GlaxoSmithKline (GSK) announced interim results of a once-daily oral dose of lapatinib (GW572016) from a phase II clinical study presented at the 40th annual meeting of the American Society of Clinical...

Manipulating master molecule disrupts vascular environment for tumors.
July 6, 2004... 2004 JUL 6 - (NewsRx.com & NewsRx.net) -- Targeting a master molecule that helps cancer cells survive when blood oxygen levels are low may offer a potentially powerful strategy for blocking tumor growth, say researchers at the University of...