Cancer Weekly articles from July 1992

Cancer Weekly archives from July 1992

Researchers say protein found in bone marrow may aid spread of prostate cancer. (Harvard Medical School)
July 6, 1992... Harvard Medical School A protein found in bone marrow appears to play an important role in the spread of prostate cancer into the bones, opening the door to possible treatments to block the cancer's advance, researchers say. ...

Researchers claim link between chlorination and cancer. (Medical College of Wisconsin)
July 6, 1992... Medical College of Wisconsin Drinking chlorinated water appears to boost the risk of developing bladder and rectal cancer report researchers who reanalyzed previous studies. The latest results indicate that drinking chlorinated...

Families of cancer fatalities can sue tobacco companies in state courts. (U.S. Supreme Court)
July 6, 1992... U.S. Supreme Court Cigarette makers may be sued under state laws for allegedly deceiving the public about the dangers of smoking, the U.S. Supreme Court ruled in a case from New Jersey. By a 7-2 vote, the justices said U.S. laws...

Woman win damages in passive smoking case. (Australia)
July 6, 1992... Australia A woman who claimed that inhaling the cigarette smoke of co-workers contributed to her emphysema has been awarded nearly $50,000 in damages from her employer - a state Health Department. Anti-smoking activists said the...

High response rate reported in breast cancer study with TLC D-99. (Liposome Co.)
July 6, 1992... Liposome Co. The Liposome Co. Inc., Princeton, New Jersey, reported that a high response rate and a good safety profile have been seen with its drug TLC D-99 in a Phase II trial of patients with metastatic breast cancer. In an...

Leukemia risk from breast cancer treatment found to be small. (U.S. National Cancer Institute)
July 6, 1992... U.S. NCI Leukemia is a rare side-effect of breast cancer chemotherapy, and the risk is far outweighed by the benefits of treatment, a study published in the June 25, 1992, issue of the New England Journal of Medicine concludes. The...

Breast cancer strategies planned at national conferences. (American Cancer Society)
July 6, 1992... American Cancer Society The American Cancer Society (ACS) has identified early breast cancer detection as a top priority for the 1990s. A nationwide delegation of 175 leaders met in New York, New York, June 21-23, 1992, for the ACS'...

Agreement to reduce breast and cervical cancer through screening and education programs. (American Cancer Society/U.S. Centers of Disease Control)
July 6, 1992... American Cancer Society/U.S. CDC The American Cancer Society (ACS) and the U.S. Centers for Disease Control (CDC) announced their intentions to formalize a collaborative agreement to reduce breast and cervical cancer among the nation's...

Black women get fewer breast exams, study finds. (U.S. National Cancer Institute)
July 6, 1992... U.S. NCI Black women who took part in a breast cancer study were less likely than white women to get an early diagnosis, an Emory University researcher reported. Dr. Ralph Coates, assistant professor of epidemiology at Emory...

Company to co-develop taxotere for Japan with Chugai. (Rhone-Poulenc Rorer)
July 6, 1992... Rhone-Poulenc Rorer Rhone-Poulenc Rorer (RPR), Collegeville, Pennsylvania, announced the signing of an agreement with Chugai Pharmaceutical Co. Ltd. for the joint development and marketing of Taxotere for the Japanese market. ...

Source of taxol to replace yew bark found. (Italy)
July 6, 1992... Italy An Italian company has agreed to supply Bristol-Myers Squibb Co., New York, New York, with a natural chemical to produce the anticancer agent taxol, currently made only from the bark of Pacific yew trees, a company spokesman says....

Animal data on daunoxome support emerging clinical profile against tumors and KS. (Vestar, Inc.) (Kaposi's sarcoma)
July 6, 1992... Vestar, Inc. A series of animal experiments have demonstrated that DaunoXome, Vestar's, (San Dimas, California) patented liposomal formulation of the established cancer drug daunorubicin, produces a nearly ten-fold increase in the amount...

Company established to develop vaccines for cancer. (Cytel Corp.)
July 6, 1992... Cytel Corp. Cytel Corp., San Diego, California, and the Scripps Research Institute, La Jolla, California, announced they have established a new company to develop novel ex vivo and in vivo therapeutic vaccines for viral diseases and...

Vitamin E prevents oral cancers. (U.S. National Cancer Institute)
July 6, 1992... U.S. NCI A study published in the June 15, 1992 issue of the American Journal of Epidemiology suggests that people who took a vitamin E supplement for at least six months had half the expected risk of oral cancers. The study,...

Cancer vaccine trial approved. (Memorial Sloan-Kettering Cancer Center)
July 6, 1992... Memorial Sloan-Kettering Cancer Center The Recombinant DNA Advisory Committee (RAC) has recommended approval of a genetically engineered cancer vaccine that seeks to jump-start an immune response in patients with metastatic melanoma or...

Researchers pioneer new bone-marrow transplant techniques. (Medical College of Wisconsin)
July 6, 1992... Medical College of Wisconsin Researchers of the Bone-Marrow Transplant Program of the Medical College of Wisconsin (MCW), Milwaukee, Wisconsin, are pursuing new methods to improve the effectiveness of bone-marrow transplantation as a...

Data from bone-marrow purging studies with oncolysin M presented at immunotoxins meeting. (Massachusetts)
July 6, 1992... Massachusetts Phase I/II clinical trials using ImmunoGen Inc.'s, Cambridge, Massachusetts, Oncolysin M indicate that the drug may provide an effective alternative for purging bone marrow of cancer cells. Clinical investigators...

Psychotherapy's value to cancer patients to be studied. (Tennessee)
July 6, 1992... Tennessee The effectiveness of group psychotherapy on women with advanced breast, lung and colon cancer will be studied by psychologists at the University of Tennessee (UT), Knoxville, Tennessee. Psychology professor Michael Nash...

Taxol dose intensification (D.I.) patients with recurrent ovarian cancer. (Research Report)
July 6, 1992... AUTHORS: G. Sarosy, E. Kohn, C. Link, D. Adams, P. Davis, F. Ognibene, B. Goldspiel, M. Christian and E. Reed. National Cancer Institute, Bethesda, Maryland. According to the authors' abstract of a poster presentation to the 28th...

Importance of cisplatin dosage in advanced ovarian cancer: survival benefit in a randomized trial. (Research Report)
July 6, 1992... AUTHORS: S.B. Kaye. Scottish Gynecological Cancer Study Group, Glasgow, Scotland. According to the author's abstract of a poster presentation to the 28th annual meeting of the American Society of Clinical Oncology, held May 17-19,...

Phase II study of gemcitabine in previously treated ovarian cancer patients. (Research Report)
July 6, 1992... AUTHORS: B. Lund, O.P. Hansen, J.P. Neijt, I. Stroier and M. Hansen. University Hospital of Copenhagen, Denmark, and Utrecht University Hospital, the Netherlands. According to the authors' abstract of a poster presentation to the 28th...

Serum CA-125 for prediction of progression in advanced epithelial ovarian carcinoma (AOC). (Research Report)
July 6, 1992... AUTHORS: W.J. Hoskins, W.P. McGuire, M.S. Brady, L. Copeland, H.D. Homesley and D.L. Clarke-Pearson. The Gynecologic Oncology Group (GOG), Buffalo, New York. According to the authors' abstract of a poster presentation to the 28th...

Inhibition of interleukin-1-alpha-induced nitric oxide synthase in vascular smooth muscle and full reversal of interleukin-1-alpha-induced hypotension by Nw-amino-L-arginine. (Periodical Report)
July 6, 1992... SOURCE: Journal of the National Cancer Institute, July 1, 1992;84(13):1008-1015. The administration of nitric oxide synthase inhibitors can reverse the cardiovascular toxicity of interleukin-1 (IL-1) at concentrations that do not...

Intraarterial infusion chemotherapy with /Sar1, Ile8~angiotensin II for bladder cancer. (Periodical Report)
July 6, 1992... SOURCE: American Journal of Clinical Oncology, June, 1992;15(3):188-193. Intraarterial infusion chemotherapy combined with a vasoconstrictor has a significant effect not only against multifocal superficial bladder cancer but also...

Promotion of aberrant crypt foci and cancer in rat colon by thermolyzed protein. (Periodical Report)
July 6, 1992... SOURCE: Journal of the National Cancer Institute, July 1, 1992;84(13):1026-1030. Thermolyzed proteins appear to be involved in human colon cancers associated with high-fat diets, according to a report from the Ontario Cancer Institute...

High frequency of p53 gene alterations associated with protein overexpression in human squamous cell carcinoma of the larynx. (Periodical Report)
July 6, 1992... SOURCE: Oncogene, June, 1992;7:1159-1166. There appears to be a pathogenic relationship between smoke carcinogen exposure and p53 inactivation in the development of carcinoma of the larynx, according to an Italian study. Squamous...

A controlled study of sustained-release morphine sulphate tablets in chronic pain from advanced cancer. (Periodical Report)
July 6, 1992... SOURCE: American Journal of Clinical Oncology, June, 1992;15(3):268-272. Sustained-release morphine sulfate (SRMS) tablets are a safe, effective analgesic preparation for patients who require oral opioids for cancer pain, and SRMS...

Using talcum powder increases risk of ovarian cancer. (Brigham and Women's Hospital/Harvard Medical School)
July 13, 1992... In the largest study ever to explore the question, researchers in Boston, Massachusetts, said there was an increased risk of ovarian cancer for women using feminine hygiene powder or baby powder made from the mineral talc. Women who...

Diet low in copper increases incidence of colon cancer in rats. (Ohio State University)
July 13, 1992... Rats fed a diet deficient in copper have a higher rate of colon cancer and larger tumors than rats fed a diet adequate in copper, new research has shown. "This study shows that a diet low in copper could be a factor in colon cancer,"...

Tests of anticancer drug fostriecin initiated. (University of Chicago)
July 13, 1992... An experimental anticancer drug, derived from bacteria found in soil samples from Brazil, is being administered for the first time to a human patient. Doctors at the University of Chicago, Chicago, Illinois, began treating a 57-year-old...

Scientists solve three-dimensional atomic structure of cancer-related enzyme. (x-ray crystallographic structure of glycinamide ribonucleotide transformylase) (Agouron Pharmaceuticals)
July 13, 1992... Agouron Pharmaceuticals Inc., San Diego, California, announced that its scientists have solved the three -dimensional atomic structure of an enzyme involved in the rapid proliferation of cancer cells. The discovery is expected to facilitate...

New test may spot early cancer spread to bone. (testing for urine levels of pyridinoline and deoxypyridinoline) (Milton S. Hershey Medical Center, Pennsylvania)
July 13, 1992... A new test may help doctors spot the early spread of cancer to the bone before it shows up on X-rays, report Researchers at Penn State's Milton S. Hershey Medical Center, Hershey, Pennsylvania. The research reveals that cancer patients...

FDA clearance to begin clinical testing of bone-marrow purging product received. (OncoPurge) (NeoRx Corp.)
July 13, 1992... NeoRx Corp., Seattle, Washington reported that it has received permission from the U.S. Food and Drug Administration to begin clinical testing of OncoPurge, a proprietary product designed to eliminate tumor cells from the bone marrow of cancer...

Phase I clinical trial of KS drug initiated. (Kaposi's sarcoma; Replistatin, recombinant platelet factor-4) (Repligen Corp.)
July 13, 1992... Repligen Corp., Cambridge, Massachusetts, announced that it has initiated a Phase I clinical trial with Replistatin (recombinant platelet factor-4) in patients with Kaposi's sarcoma (KS). This is the first clinical trial undertaken by...

Phase I clinical trial of HPV drug completed. (human papilloma virus, antisense compound ISIS 2105) (Isis Pharmaceuticals)
July 13, 1992... Isis Pharmaceuticals Inc., Carlsbad, California, announced it has completed the initial Phase I clinical trial with its antisense compound ISIS 2105 designed to treat genital warts caused by the human papilloma virus (HPV). In that...

Clinical trial contract on new drug for prostate cancer. (Roberts' Pharmaceutical Corp.'s subsidiary, VRG International, contracts with Yamanouchi U.K. Ltd.; testing tamsulosin, YM617) (Japan)
July 13, 1992... Roberts Pharmaceutical Corp., Eatontown, New Jersey, announced that Roberts' contract research organization subsidiary, VRG International, has entered into a contract with Yamanouchi U.K. Limited, a subsidiary of Yamanouchi Pharmaceutical...

A Phase II study of DuP 937 in advanced breast cancer. (Research Report)
July 13, 1992... AUTHORS: A. Goldhirsh, R. Morgan, J. Yau, J. Stewart, J. Skillings, P. O'Dwyer, B. Dallairer, N. Azarnia, J. Gyves and A. Grillo-Lopez. Civic Hospital of Lugano, Lugano, Switzerland. According to the authors' abstract of a poster...

Research links HTLV-I with primary Sjogren's syndrome. (Nagasaki University, Japan)
July 13, 1992... Researchers at Nagasaki University in Japan have determined that the presence of antibodies to HTLV-I in some patients with primary Sjogren's syndrome suggests that HTLV-I may cause primary Sjogren's syndrome, its extraglandular...

Company to expand facility for Melacine production. (melanoma theraccine) (Ribi ImmunoChem)
July 13, 1992... Ribi ImmunoChem Research Inc., Hamilton, Montana, announced plans to expand its manufacturing facility for the production of Melacine melanoma theraccine. The 8,600-square-foot addition will increase by 50 -fold Ribi ImmunoChem's...

Study on hair dyes and cancer reviewed. (U.S. Food and Drug Administration)
July 13, 1992... The U.S. Food and Drug Administration (FDA) has received inquiries about a U.S. National Cancer Institute (NCI) study of hair dye use and the risk of cancer in the July 1, 1992 issue of the American Journal of Public Health. The NCI...

Scientists disagree with hair dye study. (Washington, D.C. )
July 13, 1992... The Sheila Zahm study on hair dye safety is incorrect and needlessly alarmist, say a number of the nation's leading epidemiologists and public health academicians, responding to an article in the July 1992 issue of the American Journal of...

Agency orders hazard warnings on radiation treatment machine. (Mitsubishi International machine) (U.S. Food and Drug Administration )
July 13, 1992... A warning notice is being processed by the U.S. Food and Drug Administration (FDA) about possible hazards in the design of a cancer radiation treatment machine built by Mitsubishi International Corp. An FDA official said July 6, 1992,...

New campaign aims to boost Americans' fruit, vegetable consumption. (U.S. National Cancer Institute)
July 13, 1992... The government and the food industry are collaborating on a $93 million message to Americans - eat more fruits and vegetables to cut your risk of contracting cancer. The U.S. National Cancer Institute (NCI) has announced a five-year, $93...

Research on electromagnetics-cancer link proposed. (U.S. Department of Energy)
July 13, 1992... The U.S. Department of Energy (DOE) is proposing a $60 million, five-year research to determine if electromagnetic fields generated by power transmission lines and appliances are linked to cancer and other illnesses. The DOE hopes to...

House votes to kill subsidies for overseas tobacco promotions. (U.S. Department of Agriculture)
July 13, 1992... The U.S. House of Representatives voted to bar the use of federal money to promote U.S. tobacco overseas, after lawmakers said taxpayer dollars are being used to "peddle the ultimate carcinogen." The U.S. Department of Agriculture (USDA)...

World's first mediphotonics lab established. (City College of New York)
July 13, 1992... The world's first mediphotonics laboratory will be established at The City College of New York (CCNY) with the support of Mediscience Technology Corp., Cherry Hill, New Jersey. Mediphotonics is an emerging medical technology that utilizes...

Legislature passes Pap smear legislation. (New York)
July 13, 1992... The New York State legislature has passed a bill to require insurance policies providing hospital, surgical or medical care coverage to include coverage for cervical cytology screening (Pap smear) for women. The legislation provides that...

A Phase III randomized study comparing multiple drug chemotherapy versus standard combination for small-cell lung cancer. (Research Report)
July 13, 1992... AUTHORS: G. Bureau, J.P. Sculier, J. Klastersky, P. Libert, G. Dabouis, M. Paesmans and P. Mommen. European Lung Cancer Working Party, Brussels, Belgium. According to the authors' abstract of a presentation to the 83rd annual meeting...

New serum cancer-associated proteins as a reliable tumor marker of lung cancer and its clinical value. (Research Report)
July 13, 1992... AUTHORS: Zhang Qun-hua, Hong Xiu-ling, Ren Hui-min, Zhang Sheng-gen and Wang Bao-hua. Shanghai Fang Shan Hospital, Shanghai, China, and Shanghai Institute of Physiology, Chinese Academy of Science, Shanghai, China. According to the...

Should ovarian cancer patients receive hormone replacement therapy? AHT Trial: an international randomized controlled trial. (Research Report)
July 13, 1992... AUTHORS: R. Eeles, J. Bliss and E. Wiltshaw. AHT Trial Collaborators, Surrey, England. According to the authors' abstract of a presentation to the 83rd annual meeting of the American Association for Cancer Research, May 20-23, 1992,...

First report of Australian multicenter randomized prostate cancer trial: flutamide does not add to the effect of orchiectomy for metastatic prostate cancer. (Research Report)
July 13, 1992... AUTHORS: V. Marshall, P. Thompson, D. Raghavan, J. Zalcberg and trial group. Flinders University of South Australia; Queen Elizabeth II Hospital, Perth, Australia; Royal Prince Alfred Hospital, Sydney, Australia; and Roswell Park Cancer...

Phase II trial of dateliptium chloride hydrochloride (DHE) in metastatic breast cancer (MBC). (Research Report)
July 13, 1992... AUTHORS: F. Turpin, M. Namer, M. Splelmann, E. Vuillemin, H. Mobayen and M. Azab. Center Rene Huguenin, Saint Cloud, France, and Institute Gustave Roussy, Villejuif, France. According to the authors' abstract of a presentation to the...

Phase II study of amonifide in squamous esophageal cancer: a SWOG study. (Southwest Oncology Group) (Research Report)
July 13, 1992... AUTHORS: E. Poplin and J. MacDonald. Wayne State University, Detroit, Michigan, and Temple University, Philadelphia, Pennsylvania. According to the authors' abstract of a presentation to the 83rd annual meeting of the American...

A Phase I clinical trial of recombinant human interleukin-6 (rhIL-6) in solid tumors. (Research Report)
July 13, 1992... AUTHORS: C. Ravoet, M.J. Piccart, D. Bron, J. Kerger, D. de Valeriola, A. Awada, H. Bleiberg, S. Lips, M. Dewitte, B. Von Graffenried, C. Chatelain and P. Stryckmans. Jules Bordet Institute, Brussels, Belgium. According to the authors'...

Mediastinoscopic evaluation of state IIIA lung cancer: defining a population for pre-operative treatment trials. (Research Report)
July 13, 1992... AUTHORS: T. Lad for the Lung Cancer Study Group. University of Illinois, Chicago, Illinois. According to the author's abstract of a poster presentation to the 28th annual meeting of the American Society of Clinical Oncology, "To...

Thoracotomy staging of small cell lung cancer. (Research Report)
July 13, 1992... AUTHORS: P. Thomas, T. Lad and S. Piantodosi for the Lung Cancer Study Group, University of Illinois, Chicago, Illinois. According to the authors' abstract of a poster presentation to the 28th annual meeting of the American Society of...

Human breast cancer: prognostic significance of the C-erbB-2 oncoprotein compared with epidermal growth factor receptor. (Periodical Report)
July 13, 1992... SOURCE: Journal of Clinical Oncology, May, 1992;10(5):686-695. Overexpression of the c-erbB-2 oncoprotein appears to be an important indicator of relapse in stage I-II breast cancer, according to a European report. The c-erbB-2 (or...

Loss of heterozygosity on chromosomes 1 and 11 in carcinoma of the pancreas. (Periodical Report)
July 13, 1992... SOURCE: British Journal of Cancer, June, 1992;65:809 -812. Loss of heterozygosity on chromosomes 1 and 11 appear to be present in both exocrine and endocrine carcinoma of the pancreas, according to a British study. The loss of...

Hepatitis B virus, cigarette smoking and alcohol consumption in the development of hepatocellular carcinoma: a case-control study in Fukuoka, Japan. (Periodical Report)
July 13, 1992... SOURCE: International Journal of Cancer, June, 1992;51:509-514. Chronic hepatitis B virus (HBV) infection and smoking appears to account for 17 percent and 13 percent, respectively, of hepatocellular carcinomas (HCC) in a high incidence...

Frequent expression of the tumor antigen CAK1 in squamous-cell carcinomas. (Periodical Report)
July 13, 1992... SOURCE: International Journal of Cancer, June, 1992;51:548-554. A U.S. National Cancer Institute (NCI) study found that 81 percent of 37 samples of squamous-cell carcinoma (SCC) studied contained detectable CAK1 antigen. While the...

Analogues of LHRH versus orchidectomy: comparison of economic costs for castration in advanced prostate cancer. (luteinizing hormone releasing hormone) (Periodical Report)
July 13, 1992... SOURCE: British Journal of Cancer, June, 1992;65:927 -929. Luteinizing hormone releasing hormone (LHRH) can be used in place of surgical castration in roughly 85 percent of advanced prostate cancer patients at a significant economic...

Second primary tumors in patients with oral cancer. (Periodical Report)
July 13, 1992... SOURCE: Cancer, July 1, 1992;70(1):14-19. There is a higher rate of cancer recurrence among patients with oral cancer than any other cancer, and these patients should have close medical supervision, according to a report from the U.S....

Interferon A-2B approved for hepatitis B. (U.S. Food and Drug Administration)
July 20, 1992... U.S. FDA The U.S. Food and Drug Administration (FDA) announced July 13, 1992, approval of recombinant interferon a-2b injections as the first treatment for chronic hepatitis B, an infectious liver disease that can lead to cirrhosis,...

Cancer mortality patterns shift, reflecting cultural changes. (East Asia)
July 20, 1992... East Asia In terms of cancer mortality, development and Westernization have brought mixed blessings to East Asia, report researchers in the July 15, 1992, issue of the Journal of the National Cancer Institute. Stomach cancer, a...

Ignorance helps spread cancer-causing parasite. (Bilharzia, or Schistosoma) (Nigeria)
July 20, 1992... Nigeria Bilharzia, a disease caused by the penetration of a small infectious parasite, has become a major problem in Nigeria and other rural areas of Africa. The parasite enters into the skin while the person wades, swims or bathes...

Breast cancer in males still indicates risk to relatives. (M.D. Anderson Cancer Center)
July 20, 1992... M.D. Anderson Cancer Center No matter whether breast cancer patients are male or female, their female relatives still run double the expected risk of developing the disease, a study reported in the July 15, 1992 issue of the Journal of...

Role of p53 protein in breast cancer examined. (Finland)
July 20, 1992... Finland Overexpression of p53 protein, resulting from mutations of the p53 suppressor gene, indicates high metastatic potential in axillary node-negative (ANN) breast cancer, indicates a study reported in the July 15, 1992 issue of the...

p53 gene might be sunlight's trigger for basal cell carcinoma. (University of Texas Medical Branch)
July 20, 1992... Texas Sunlight might help cause the most common cancer in humans - basal cell carcinoma (BCC) - by scuttling a well known cancer-suppressing molecule called the p53 gene, according to researchers at the University of Texas Medical Branch...

Cancer research organization dismantles operations. (International Coordinating Council for Cancer Research)
July 20, 1992... ICCCR The International Coordinating Council for Cancer Research (ICCCR) ceased operations in June 1992, according to a report in the July 15, 1992, issue of the Journal of the National Cancer Institute. Its chairman and founder,...

Link undetermined between dietary fat and breast cancer. (University of Minnesota)
July 20, 1992... University of Minnesota A study in the July 15, 1992, issue of the Journal of the National Cancer Institute, using four analytic approaches to adjustment for energy intake, found a modest positive association of total fat intake with...

Nutrition, cancer link established. (American Association for Clinical Chemistry)
July 20, 1992... American Association for Clinical Chemistry Cancer risk can be affected by many different dietary factors, from fat to vitamin E, scientists attending the July 19-23, 1992, meeting of the American Association for Clinical Chemistry being...

Hospital lab is key to better nutrition. (American Association for Clinical Chemistry)
July 20, 1992... American Association for Clinical Chemistry Clinical laboratories in hospitals are the key to better patient nutrition and faster discharge, scientists attending the July 19-23, 1992, meeting of the American Association for Clinical...

U.S. ban against cancer-causing pesticides in processed foods upheld. (Delaney Clause) (California)
July 20, 1992... California In a unanimous decision by the U.S. Court of Appeals in California, the court upheld the Delaney Clause, a federal law banning the use of cancer-causing pesticides in foods that are ultimately processed. The case was...

State issues hazard alert on hexavalent chromium. (California)
July 20, 1992... California State Health Director Molly Joel Coye, M.D., M.P.H., issued a Hazard Alert to warn that hexavalent chromium, a chemical widely used in California workplaces, presents an extremely high risk of lung cancer to workers. ...

Researchers find pre-development of cancer could start before birth. (U.S. National Cancer Institute)
July 20, 1992... U.S. NCI Some people might be born with a propensity to get cancer, according to a study by researchers at the U.S. National Cancer Institute (NCI). Dr. Lucy Anderson of the NCI said her lab has just finished the first animal...

Drug trials possible in untreated SCLC. (small cell lung cancer) (Johns Hopkins Oncology Center)
July 20, 1992... Johns Hopkins Oncology Center A study reported in the July 15, 1992, issue of the Journal of the National Cancer Institute suggests that new anticancer drugs can be evaluated in selected untreated patients with extensive-stage small-cell...

rVaccinia-cea vaccine displays antitumor activity. (recombinant vaccinia-carcinoembryonic antigen) (U.S. National Cancer Institute)
July 20, 1992... U.S. NCI In the July 15, 1992, issue of the Journal of the National Cancer Institute, Kantor et al. report that the rV(NYC)-CEA vaccine - constructed by recombining the human carcinoembryonic antigen (CEA) gene to the New York City...

Phase III clinical trials of Ceprate SC Stem Cell Concentration System initiated. (CellPro Inc.)
July 20, 1992... CellPro Inc. CellPro Inc., Bothel, Washington, announced the beginning of Phase III human clinical trials of its Ceprate SC Stem Cell Concentration System in autologous bone-marrow transplantation to treat breast cancer. The Phase...

Genetic tests pose new ethical issues. (American Association for Clinical Chemistry)
July 20, 1992... American Association for Clinical Chemistry Genetic and infant screening tests will pose difficult ethical and legal issues for both practitioners and society, scientists attending the July 19-23, 1992, meeting of the American...

Despite risk, many hospital workers don't wash hands. (Iowa)
July 20, 1992... Iowa Healthcare workers could substantially reduce the number of infections they transmit to patients by washing their hands more frequently, a new study concludes. Despite aggressive education efforts, hospital staffers often...

Termination and phase out of Outstanding Investigator Grant awards. (Research Report)
July 20, 1992... AUTHORS: NIH Guide, Volume 21, Number 24, July 3, 1992, P.T. 34; K.W. 1014006, National Cancer Institute. The National Cancer Institute (NCI), with the concurrence of the National Cancer Advisory Board, announces plans for the orderly...

Molecular interventions for environmentally induced disease prevention. (National Institute of Environmental Health Sciences research grant announcement) (Research Report)
July 20, 1992... AUTHORS: NIH Guide, Volume 21, Number 24, June 26, 1992, RFA Available: ES-92-03, P.T. 34; K.W. 0725005, 1007009, 0760003, National Institute of Environmental Health Sciences. Application Receipt Date: November 24, 1992. The request...

A randomized trial to improve adherence among women with prior abnormal mammograms. (Research Report)
July 20, 1992... AUTHORS: C. Lerman, B. Rimer and P. Engstrom. Fox Chase Cancer Center, Philadelphia, Pennsylvania. According to the authors' abstract of a poster presentation to the 28th annual meeting of the American Society of Clinical Oncology,...

Beta-carotene in oral leukoplakia. (Research Report)
July 20, 1992... AUTHORS: H. Garewal, J. Pitcock, S. Friedman, D. Alberts, F. Meyskens, L. Ramsey, Y.M. Peng and K. Girodias. Arizona Cancer Center, Tucson, Arizona, and University of California Clinical Cancer Center at Irvine. According to the...