Cancer Weekly articles from January 2003

Cancer Weekly archives from January 2003

Growth factor antagonists may reverse course of hematologic cancer.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Antagonists that block the activity of angiogenic growth factors could be key to treating acute myeloid leukemia. Researchers at Children's Hospital...

Adenoviral transfer of p27 gene decreases squamous cell carcinoma.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - The members of a research team in Seoul, Korea, have used p27 gene therapy to change the characteristics of head and neck squamous cell carcinoma (HNSCC) cells...

Herceptin pretreatment enhances Taxol's effect in ErbB2-overexpressing cells.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- M.D. Anderson Cancer Center researchers point out that "[t]he recombinant humanized anti-ErbB2/HER2 monoclonal antibody Herceptin (Trastuzumab) has been shown to significantly enhance the tumoricidal...

Pancreatic cancer research should focus on antigen presentation, targeted drug delivery.( )
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - The most promising avenues of research into T cell targeting immunotherapy for pancreatic cancer are dendritic cell vaccines, methods of enhancing...

Scientists discover mechanism by which cells rid themselves of damaged proteins.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- Scientists at the University of Texas (UT) Southwestern Medical Center at Dallas have identified a new and surprising mechanism by which a class of enzymes responsible for the breakdown of proteins...

p53 mutation may contribute to tumor progression.(head and neck cancer)
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- Researchers in Italy "examined whether the expression of matrix metalloproteinase in head and neck squamous cell carcinoma is correlated with other steps involved in tumor growth and metastasis, like...

Did nuclear bomb increase hepatitis C-related liver cancer risk?
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Interactions between radiation and hepatitis C virus (HCV) infection may have exacerbated the risk for primary liver cancer in atomic bomb survivors in Japan....

Diabetes decreases prostate cancer risk.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - Results from a large cohort study done in Sweden indicate that men with diabetes have a reduced risk of prostate cancer, especially if they have been...

Effective tumor targeting visualized by redirected CD8+ natural killer T cells.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- "HER2 is an attractive immunotherapeutic target for neoplastic disease because this cell surface molecule is overexpressed on a large fraction of malignant tumor cells," write Stanford University,...

Kallistatin is a new inhibitor of tumor neovascularization and growth.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- Medical University of South Carolina biochemists think the compound kallistatin could have a place in cancer gene therapy. "Kallistatin is a unique serine proteinase inhibitor (serpin) and a...

Enhanced bone marrow angiogenesis may have prognostic value in early disease.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- Researchers in Italy say their study results suggest there may be a causal relationship between risk of disease progression and bone marrow angiogenesis in B-cell chronic lymphocytic leukemia. ...

Glioblastoma in Asian population shows evidence of a distinct genetic pathway.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- Prevalence of p53 mutations in a Thai population indicates there may be a genetic component to development of glioblastoma multiforme in this group. "In Singapore, astrocytic tumors occur in only...

Update provided on regulatory status of RSR13.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- Allos Therapeutics, Inc., (ALTH) announced that following a recent meeting with the oncology drug products division of the Food and Drug Administration (FDA), the company may begin a rolling submission...

Ganciclovir pellets enhance effects of suicide gene therapy.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Sustained release of ganciclovir appears to enhance the ability of suicide gene therapy to eradicate human brain cancer cells in rats. Ganciclovir is a...

Change on enzyme gene may associate with invasive disease.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - A solitary polymorphism on the promoter that drives matrix metalloproteinase (MMP)-3 may be responsible for the invasive nature of some breast cancers. ...

Improvements in disease-free survival reported with adjuvant dose-dense chemotherapy.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- New data from a large phase III study of 2005 women with node-positive breast cancer show that when Taxol (paclitaxel) (T) is given with standard chemotherapy, doxorubicin (A) and cyclophosphamide (C),...

New 3-D mammography system may improve breast imaging.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- A new approach to mammography, developed by researchers at Massachusetts General Hospital (MGH), holds the potential for greatly improving the detection of breast lesions and the ability to predict...

Reconstructive breast surgery rates low in Canada.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- A low rate of breast reconstruction among women who have had a mastectomy may be due to a lack of knowledge about the procedure by referring physicians, says a University of Toronto study. Breast...

Study shows TS-2000 system 100% sensitive in detecting breast lesions under 1 cm.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- Data presented at the annual scientific meeting of the Radiological Society of North America (RSNA) shows that TransScan Medical, Ltd.'s TS-2000 system, a noninvasive imaging device that assists in the...

Technique reveals drug resistance in tumors, could prevent unnecessary chemo.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- Oncologists at the Duke Comprehensive Cancer Center are testing a new technique called gene expression profiling that subtypes each breast cancer tumor by its genetic defects so that doctors can tailor...

VIDAR unveils newest film digitizer.(Brief Article)
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- VIDAR Systems Corp., a manufacturer of medical film digitizers, has launched its newest digitizer, the CAD PRO, designed specifically for the application of computer aided detection (CAD) for screening...

Vaccine generates strong immune response in women with advanced disease.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- Dendreon Corp. (DNDN) has announced that results of a phase I study indicate that APC8024, the company's investigational therapeutic vaccine for breast, ovarian and colon cancer appears to be safe and...

Zometa significantly reduces bone complications.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- Zometa (zoledronic acid for injection) significantly reduced the risk of developing a skeletal-related event (SRE) when compared to pamidronate disodium for injection (Aredia) in advanced breast cancer...

Adenoviral transduction of tumor cells induces apoptosis in cocultured T cells.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- According to oncologists in Germany, "Adenoviral gene transfer of immunomodulatory molecules has been employed successfully in tumor vaccination studies to induce rejection of transplanted syngeneic...

CD40-targeted adenoviral vectors show promise for tumor immunotherapy.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- CD-40-targeted adenoviral vectors may be a "new vaccine modality for tumor immunotherapy," report pathologists in the Netherlands. "Therapeutic tumor vaccination with viral vectors or naked DNA,...

Coactive strategy boosts IL-18 antitumor effect.(interleukin)
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- According to recent research from Japan, "Interleukin-18 is a potent cytokine expressed early in the immune response following cleavage in activated composes. We have investigated the in vivo antitumor...

Phage-display selection technique for specific human scFv antibody described.(single-chain Fv)
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- "Overexpression of the cell-surface glycosphingolipid G(M3) is associated with a number of different cancers, including those of the skin, colon, breast, and lung. Antibodies against the G(M3) epitope...

Recombinant E. coli vaccine promotes MHC class I-dependent antigen presentation.(major histocompatibility complex)
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- Cancer researchers in England "have examined the potential of recombinant Escherichia coli expressing listeriolysin 0 (LL0) to deliver tumor antigens to dendritic cells (DCs) for cancer immunotherapy."...

Two antigens may be targets in desmoplastic small round cell tumor.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- Cancer researchers have identified two tumor antigens - the disialogan-glioside G(D2) and a novel antigen using antibody 8H9 - as possible immunotherapy targets against desmoplastic small round cell...

FGF-like autoantibodies may arise spontaneously in hypercalcemia.(fibroblast growth factor)
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- Researchers report a possible association between increased immunoglobulin G (IgG)-like endothelial cell activity in serum from a hyperprolactinemic subset of cancer-associated hypercalcemic subjects...

RF Technology reduces pain in bone cancer patients.(radio frequency)
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- RITA Medical Systems, Inc., (RITA) announced that the results of a multicenter study on the use of its proprietary radiofrequency (RF) ablation technology confirm that the minimally invasive procedure...

Researchers solve 3-D atomic structure of Aurora-2 kinase.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- Researchers from Vertex Pharmaceuticals, Inc., (VRTX) have published the first 3-dimensional atomic structure of Aurora-2, a protein kinase implicated in the growth of cancer cells. Vertex...

Additional phase I data presented on liposomal antisense agent.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- NeoPharm, Inc., (NEOL) announced additional phase I clinical trial data on LErafAON, the company's investigational NeoLipid liposomal antisense agent. A scientific poster was presented at the 14th...

Clinical data on VNP40101M reported at EORTC-NCI-AACR meeting.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- Vion Pharmaceuticals, Inc., (VION) reported clinical results from a phase I trial of its anticancer agent VNP40101M in solid tumors in a poster presentation at the EORTC-NCI-AACR 2002 meeting on...

Pilot program explores viability of cell-penetrating peptide-based drugs.(Brief Article)
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- CeMines, Inc., a privately held company that is developing proprietary Molecular FingerPrinting technology for early detection and treatment of cancer, announced that it has entered into a pilot program...

Preclinical data shows synergy of TLK286 in combination with chemo drugs.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- Telik, Inc., (TELK) presented preclinical results describing the synergistic cancer cell growth inhibitory effects of TLK286 administered in combination with approved cancer chemotherapeutic drugs. ...

DNA vaccine elicits humoral and cellular immune responses in lymphoma patients.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - A vaccine containing DNA encoding tumor immunoglobulin from patients with follicular B-cell lymphoma was shown to be safe and immunogenic in phase...

Tumor cell lysate-pulsed DC effective for T-cell lymphoma immunotherapy.(dendritic cells)
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- According to a study from the United States, "TCR Id protein conjugated to keyhole limpet hemocyanin (KLH) (TCR Id:KLH) and injected with a chemical adjuvant (QS-21) induces a protective, Id-specific...

Genasense shows single-agent activity in patients with advanced CLL.(chronic lymphocytic leukemia)
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- Genta, Inc., (GNTA), in collaboration with Aventis (AVE), announced the presentation of new clinical data that shows activity of the company's lead anticancer compound, Genasense, as a single agent in...

Diagnostic, therapeutic uses beyond thyroid seen for sodium iodide symporter.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- Mayo Clinic endocrinologists are excited about potential applications for the sodium iodide symporter in cancer diagnostics and therapeutics beyond the thyroid gland, with which it typically is...

Hepatitis C virus presents risk for liver cancer in adults with AIDS.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Government researchers have established a connection between hepatitis C virus (HCV) infection and liver cancer but not HCV infection and non-Hodgkin lymphoma...

Data presented on Nipent shows its capability as a franchise compound.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- SuperGen, Inc., (SUPG) announced that 12 abstracts and presentations on the company's anticancer drug, Nipent, validating the drug's capability as a franchise compound with the ability to treat a...

No more medical roulette: Publisher says internet will change in 2003.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- NewsRx is celebrating its twentieth year as a publisher by adding 20 new weeklies. The company's CEO is predicting major changes in the publishing industry and Internet in 2003. The Atlanta-based...

Phase I trial data on novel bispecific molecule H22xKi-4 reported.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- Researchers at the University of Cologne, Germany, have reported phase I trial data on a molecule they developed for immunotherapy of Hodgkin lymphoma. They say their results indicate further clinical...

Aflatoxin exposure adds to hepatocellular carcinoma risk for HBV infected.(hepatitis B virus)(Brief Article)
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- Conditions resulting in expression of the hepatitis B virus (HBV) X protein may increase the risk of hepatocellular carcinoma in people infected with HBV, virologists report. "Humans chronically...

Hepatitis-associated cancer prevented by anti-Fas ligand antibody therapy.(Brief Article)
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- Oncologists in Japan have demonstrated that improving chronic inflammation in an animal model by anti-Fas ligand antibody therapy resulted in reduced hepatocellular carcinoma development. "A...

Real-time PCR of HBV DNA in tumorous and surrounding tissue yields useful data.(polymerase chain reaction, hepatitis B virus)
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- Real-time quantitation of hepatitis B virus (HBV) DNA in tumorous and surrounding tissue from patients with hepatocellular carcinoma provides useful information about this disease association, say...

Clinical data: RF technology effective in treating cancerous lung tumors.(radiofrequency)(Brief Article)
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- RITA Medical Systems, Inc., (RITA) announced that the results of a clinical study on the use of its proprietary radiofrequency (RF) ablation technology confirm that the minimally invasive treatment...

M2BP has use as a tumor marker and target antigen in cancer immunotherapy.(Mac-2 binding protein)
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- Researchers report 90K/Mac-2 binding protein (M2BP) has potential as a tumor marker and as a target antigen in immunotherapy for lung cancer. Y. Ozaki and colleagues, Shiga University of Medical...

New evidence links smoking and lung cancer in women.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- A Mayo Clinic study of more than 41,000 postmenopausal women in Iowa provides new evidence that the most common type of lung cancer in women is more closely linked to smoking cigarettes than previously...

Research: Combidex can detect lymph node disease in prostate and renal cancer.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- Advanced Magnetics, Inc., (AVM) and Cytogen Corp. (CYTO) announced the presentation of data showing that Combidex, an investigational magnetic resonance imaging (MRI) contrast agent, is able to...

Phase II study data reported on rituximab + fludarabine immunotherapy.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- A combined immunotherapy regimen of rituximab and fludarabine was shown to be feasible and effective in patients with chronic lymphocytic leukemia and who had not received these compounds before. ...

Human antibody MDX-060 demonstrates antitumor activity in animal models.(Brief Article)
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- Medarex, Inc., (MEDX) announced that treatment with its fully human antibody, MDX-060, resulted in substantial tumor regression in SCID mice xenografted with CD30-positive lymphomas, with complete...

Phase I/II data presented for IL13-PE38.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- NeoPharm, Inc., (NEOL) announced that additional phase I/II clinical trial data on IL13-PE38, the company's novel tumor-targeting agent for malignant glioma, were presented at the seventh annual meeting...

PHLDA1/TDAG51 downregulation contributes to tumor growth, metastases.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- Immunologists in Germany report that "progressive loss of PHLDA1 expression in melanomas may play a role in deregulated cell growth and apoptosis resistance in these tumors." R. Neef and colleagues...

Farnesyl transferase inhibitors may have therapeutic potential.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- Cancer researchers in Germany report that treatment of human multiple myeloma cells with an interleukin-6 antagonist or "an anti-gp130 monoclonal antibody induced apoptosis if the cells were cultured in...

Novel drug continues to show promise in early study.(Velcade for treating multiple myeloma)
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- A first-in-class investigational drug for relapsed and refractory multiple myeloma, an incurable cancer of the bone marrow, continues to show promising results in a study of myeloma patients who have...

Studies suggest decitabine is effective in elderly MDS patients.(myelodysplastic syndrome)
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- SuperGen, Inc., (SUPG) announced that clinical studies suggest the anticancer drug decitabine is effective in elderly patients with high-risk myelodysplastic syndrome (MDS). The results were...

Tumor suppressor protein capable of igniting neuron differentiation.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Researchers in Japan have been able to make neuroblastoma cancer cells behave like normal neurons with gene transfer. According to Hidetoshi Murata and...

Positive pivotal phase II/III clinical trial results achieved for Onco TCS.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- Inex Pharmaceuticals Corp. (IEX) announced it has achieved positive results from a pivotal phase II/III clinical trial evaluating its lead anticancer product Onco TCS as single-agent therapy for...

Trial evaluates dosing and scheduling of adjuvant administered with personalized immunotherapy.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- Genitope Corp. has announced promising results of a phase II clinical trial to evaluate dosage and scheduling of an adjuvant which is administered with the company's personalized vaccine-like...

FDA approves Taxotere for first-line treatment of patients.(Brief Article)
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- Aventis announced that its chemotherapeutic agent Taxotere (docetaxel) for Injection Concentrate was approved by the United States Food and Drug Administration (FDA) as first-line therapy in patients...

Nitric oxide indicted in angiogenesis of oral dysplasia.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Scientists in England have implicated nitric oxide synthase (NOS) type 2 in the angiogenesis of oral dysplasia. Nitric oxide (NO) is formed upon the...

Antiangiogenic agent, Neovastat, induces endothelial cell apoptosis.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- Researchers at the University of Quebec report that the antiangiogenic agent, Neovastat - a product of AEterna, also located in Quebec - induces apoptosis specifically in endothelial cells. ...

Angiogenesis, proliferation, and apoptosis could be biomarkers for therapy.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- According to recent research from the United States, "Proliferation, apoptosis, and angiogenesis are critical biologic processes altered during carcinogenesis. Surrogate biomarkers of these processes...

Antithrombin recognized as antiangiogenesis source in low-grade tumors.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Low-grade prostate tumors express anti-thrombin, according to researchers in Sweden. "Anti-thrombin, a member of the serpin family and an inhibitor of...

Assessments help physicians become more aware of quality-of-life issues.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- Incorporating standardized health-related quality-of-life (HRQL) assessments in cancer treatment settings can improve communication between doctors and patients about the patient's overall well-being,...

Serum angiogenic activity isn't correlated with prognosis.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- Urologists in Germany report that angiogenic activity in renal cell carcinoma patients' sera doesn't correlate to pathologic stage and grade of their disease. "Angiogenesis is essential for tumor...

More rare childhood cancer cases reported in Nevada.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- State health officials are monitoring a surge in a rare form of childhood cancer in Nevada, with at least 5 cases reported over the past 2 years, the Reno Gazette-Journal reported December 9, 2002. ...

Self-help program for pregnant smokers is ineffective.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- The U.K. government wants to cut the percentage of women who smoke during pregnancy from 23% to 15% by the year 2010. But a new study finds that a self-help approach implemented during routine...

Human leukocyte antigen alleles affect graft-versus-host disease risk.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in Sweden have identified several factors affecting the risk of graft-versus-host reactions after hematopoietic stem cell transplantation (HSCT)....

Interleukin-18 doesn't disrupt antileukemia effects.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - The gamma interferon-inducing cytokine interleukin (IL)-18 can be safely used to ameliorate graft-versus-host reactions after stem cell transplantation,...

New system speeds mapping of blood vessel networks in live tumors.
January 7, 2003... 2003 JAN 7 - (NewsRx.com & NewsRx.net) -- Rensselaer researchers have developed an automated system, called RPI-Trace3D, that can swiftly map capillaries in a live tumor. What used to take days of manually tracing the vessels, now takes 2...

Oral citrus derivative derails tumor growth and angiogenesis.(pectin)
January 14, 2003... 2003 JAN 14 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Medical researchers argue that the inclusion of some carbohydrate compounds in the diet can go a long way towards preventing and even treating cancer. The...

Serum growth factor relays status of laryngeal carcinoma.
January 14, 2003... 2003 JAN 14 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Researchers suspect serum levels of vascular endothelial growth factor (VEGF) can provide clues about the aggressiveness of laryngeal squamous cell carcinoma....

New method of delivering chemotherapy using ultrasound works in BYU lab.(Brigham Young University)
January 14, 2003... 2003 JAN 14 - (NewsRx.com & NewsRx.net) -- Cancer patients undergoing chemotherapy often endure painful side effects caused by the powerful drugs as they course through their entire bodies, damaging healthy tissue and tumors alike. Brigham...

Tumor cell-pulsed dendritic cells extend survival of mice with T cell lymphoma.
January 14, 2003... 2003 JAN 14 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - Dendritic cells (DCs) pulsed with lysates of murine C6VL T cell lymphoma cells protected mice against a lethal dose of C6VL cells and significantly...

Gastrointestinal transit slows in patients with primary liver cancer.
January 14, 2003... 2003 JAN 14 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Researchers in Taiwan have learned that slowed gastrointestinal transit plagues primary liver cancer patients just as much as it does those diagnosed with...

Treatment shows promise in study of patients with relapsing disease.
January 14, 2003... 2003 JAN 14 - (NewsRx.com & NewsRx.net) -- Peptide vaccination of acute myelogenous leukemia patients can elicit highly active specific immunity against leukemia cells and induce remission, according to a study conducted by researchers at the...

In vivo angiogenic activity correlates with MYCN oncogene overexpression.
January 14, 2003... 2003 JAN 14 - (NewsRx.com & NewsRx.net) -- "Neuroblastoma (NB) is the most common malignant solid tumor in early childhood. Amplification of the MYCN oncogene is associated with a more malignant course of disease and poor outcome. The role...

Dominant negative inhibition a way to curb cancer growth.
January 14, 2003... 2003 JAN 14 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Adenoviruses expressing truncated insulin-like growth factor receptor can staunch the growth of human lung cancer cells. Scientists in the United States and...

Combination chemotherapy may produce remission.
January 14, 2003... 2003 JAN 14 - (NewsRx.com & NewsRx.net) -- A novel chemotherapy regimen that combines standard drugs with an antibody-targeted agent has shown early success in treating adults with acute myeloid leukemia, according to preliminary data from a...

Aranesp more cost-effective than Epoetin alfa.
January 14, 2003... 2003 JAN 14 - (NewsRx.com & NewsRx.net) -- Amgen (AMGN) announced results from a study presented at the American Society of Hematology (ASH) in which Aranesp (darbepoetin alfa) was shown to be 13% less expensive than Epoetin alfa while...

Radiation said to help with brain defect.
January 14, 2003... 2003 JAN 14 - (NewsRx.com & NewsRx.net) -- With the zap of a beam, 5-year-old Whitney Boyce took a leap toward possible recovery from a brain defect that has tyrannically worked to deprive other parts of her body of blood since she was born....