Cancer Weekly articles from January 2001

Cancer Weekly archives from January 2001

Three Genetic Steps Convert Normal Cells into Cancer Cells.
January 9, 2001... 2001 JAN 9 - (NewsRx.com & NewsRx.net) -- Cells originating from normal human breast tissue have been converted into breast cancer cells by a defined protocol of genetic changes. In the January 1, 2001, issue of Genes & Development, Dr....

Study Finds No Increased Risk from Handheld Cellular Telephones.
January 9, 2001... 2001 JAN 9 - (NewsRx.com & NewsRx.net) -- The use of handheld cellular telephones does not appear to be associated with the risk of brain cancer, but further studies are needed to account for longer induction periods, especially for...

Compounds Exhibit Synergistic Activity with Herceptin and Taxotere.
January 9, 2001... 2001 JAN 9 - (NewsRx.com & NewsRx.net) -- New research reported December 8, 2000, at the annual San Antonio Breast Cancer meeting showed that exisulind (Aptosyn(TM)) and CP461 inhibit cell growth and trigger apoptosis in human breast cancer...

Data Show Older Lymphoma and Breast Cancer Patients are Under-Treated.
January 9, 2001... 2001 JAN 9 - (NewsRx.com & NewsRx.net) -- According to data presented at the American Society of Hematology (ASH) meeting and the San Antonio Breast Cancer Symposium held in December 2000, elderly cancer patients may be up to two times as...

Risk May Be Linked to Altered Pattern of Gene Activation.
January 9, 2001... 2001 JAN 9 - (NewsRx.com & NewsRx.net) -- Scientists have proposed that predisposition to colorectal cancer may be linked to changes in the activation pattern of a gene called insulin-like growth factor II (IGF2). The IGF2 gene is one of...

Young Adult Cancer Survivors Exhibit Post-traumatic Stress Disorder.
January 9, 2001... 2001 JAN 9 - (NewsRx.com & NewsRx.net) -- According to a new study, one-fifth of young adults who have been cured of childhood cancer show symptoms of post-traumatic stress disorder, a post-war phenomenon that when applied to the experience of...

Elevated Matrix Metalloproteinase-9 Levels Can Be Warning Sign.
January 9, 2001... 2001 JAN 9 - (NewsRx.com & NewsRx.net) -- Oncologists in Germany report that higher-than-normal levels of the enzyme matrix metalloproteinase-9 (MMP-9) can be a red flag for the presence of head and neck cancer. "Matrix metalloproteinases...

2-Methoxyestradiol Induces Programmed Cell Death in Hepatoma Cultures.
January 9, 2001... 2001 JAN 9 - (NewsRx.com & NewsRx.net) -- Researchers announced at the U.S. National Cancer Institute's EORTC-AACR Symposium on New Drugs in Cancer Therapy that 2-methoxyestradiol (2-ME), a metabolite of estrogen, induces apoptosis in hepatoma...

Aggressive Follow-Up Necessary to Locate Secondary Malignancies.
January 9, 2001... 2001 JAN 9 - (NewsRx.com & NewsRx.net) -- Aggressive surgical removal of second lung cancers resulted in five- and 10-year survival rates of 33% and 10%, respectively, among a series of 37 patients in a study published in the December 2000...

Investigational New Drug Application Filed for PEG-Paclitaxel.
January 9, 2001... 2001 JAN 9 - (NewsRx.com & NewsRx.net) -- Enzon, Inc. announced December 18, 2000, that it has submitted an Investigational New Drug (IND) application to the U.S. Food and Drug Administration (FDA) for PEG-paclitaxel. PEG-paclitaxel is a...

New Neutron Capture Therapy Facility Commissioned at MIT.
January 9, 2001... 2001 JAN 9 - (NewsRx.com & NewsRx.net) -- A promising form of therapy for brain cancer and melanoma found a new home with the commissioning on December 4, 2000, of an Massachusetts Institute of Technology (MIT) facility that is the best of its...

Advisory Panel Makes Recommendations for New Listings.
January 9, 2001... 2001 JAN 9 - (NewsRx.com & NewsRx.net) -- An expert advisory panel recommended on December 15, 2000, to the U.S. government that steroidal estrogens be listed as a "known" cause of cancer in humans in a future issue of the Report on...

Advisory Committee Recommends Monoclonal Antibody Therapy.
January 9, 2001... 2001 JAN 9 - (NewsRx.com & NewsRx.net) -- The Oncologic Drugs Advisory Committee (ODAC) to the U.S. Food and Drug Administration (FDA) voted December 14, 2000, 14 to one to recommend accelerated approval of Millennium & ILEX Partners L.P.'s...

Co-Development of Nucleoside Analog Announced.
January 9, 2001... 2001 JAN 9 - (NewsRx.com & NewsRx.net) -- Bioenvision announced December 13, 2000, that it had signed a letter of intent with a U.S. biopharmaceutical company for the co-development of clofarabine, a nucleoside analog currently in a Phase II...

Therapeutic Antibody Licensed for Late-Stage Disease.
January 9, 2001... 2001 JAN 9 - (NewsRx.com & NewsRx.net) -- Amgen (AMGN), Thousand Oaks, California, and Immunomedics, Inc. (IMMU), Morris Plains, New Jersey, announced that the companies have signed an agreement to license to Amgen a novel cancer therapeutic...

Survey Underscores Need for Education and Early Detection.
January 9, 2001... 2001 JAN 9 - (NewsRx.com & NewsRx.net) -- While substantial inroads have been made in detecting and educating people about various cancers, a new survey unveils key findings about what appears to be the next frontier in public health: oral...

First Clinical Use of BrachySeed Therapy in U.S. and Canada Announced.
January 9, 2001... 2001 JAN 9 - (NewsRx.com & NewsRx.net) -- Cytogen Corp. (CYTO), Princeton, New Jersey, and Draxis Health, Inc. (DRAX; DAX), Mississauga, Ontario, Canada, announced the first clinical use of BrachySeed in both the U.S. and Canada. ...

High Intensity Ultrasound to be Tested in Localized Clinical Trials.
January 9, 2001... 2001 JAN 9 - (NewsRx.com & NewsRx.net) -- Misonix, Inc., announced December 14, 2000, that the U.S. Food and Drug Administration (FDA) has granted approval for commencement of the Focus Surgery's study of High Intensity Ultrasound (HIFU) using...

Mosaic Tumor Blood Vessels Could be New Anti-Cancer Target.
January 9, 2001... 2001 JAN 9 - (NewsRx.com & NewsRx.net) -- For more than 50 years, scientists have reported that cancer cells are located in the walls of so-called "mosaic" tumor blood vessels, which are lined by both normal endothelial cells and tumor cells....

Vascular Endothelial Growth Factor and Angiogenesis Not Confined to Solid Tumors.
January 9, 2001... 2001 JAN 9 - (NewsRx.com & NewsRx.net) -- According to an investigation conducted at the University of Liverpool, vascular endothelial growth factor (VEGF) and angiogenesis are not confined to solid cancer tumors, but can be found in relation...

Clinical Trial Initiated with Chemorefractory Patients.
January 9, 2001... 2001 JAN 9 - (NewsRx.com & NewsRx.net) -- Aphton, a company with products in pivotal and late-stage clinical trials for cancer therapy, is commencing a clinical trial with patients who have failed the approved chemotherapy regimen (5-FU and...

Heat-Sensitive Liposome Improves Chemotherapy Delivery to Tumors.
January 9, 2001... 2001 JAN 9 - (NewsRx.com & NewsRx.net) -- A tiny, fat-based, spherical structure called a liposome, modified at Duke University to be sensitive to mild heating, can triple the amount of an anti-cancer drug delivered to tumors in mice compared...

Gene Therapy Can Induce Systemic Immune Response, But Treatment Still Not Very Effective.
January 9, 2001... 2001 JAN 9 - (NewsRx.com & NewsRx.net) -- Intracerebral, retrovirus-mediated, somatic gene therapy of primary glioblastoma multiforme does induce a systemic immune response in human patients, a recent study has shown, but the treatment exerted...

Cervical Carcinogenesis Curbed by HPV Oncogene Repression.
January 9, 2001... 2001 JAN 9 - (NewsRx.com & NewsRx.net) -- Repression of human papillomavirus (HPV) E6 and E7 proteins can reverse cervical carcinogenesis. How? These proteins neutralize cells' natural tumor suppressor function, report researchers from...

Endothelin-1 and Endothelin-A Receptor: Targets for Cancer Therapy?
January 9, 2001... 2001 JAN 9 - (NewsRx.com & NewsRx.net) -- Endothelin-1 (ET-1) induces the growth of human papillomavirus (HPV) cells, which express endothelin-A receptors (ETAR). Thus, these receptors may be appropriate targets for anticancer therapy,...

Information Key Ingredient for Healthy World; NewsRx.net Offers eHealth Revenue Sharing Booster Shot.
January 9, 2001... 2001 JAN 9 - (NewsRx.com & NewsRx.net) -- Health information from the Internet is the key ingredient for advancing world health, according to health publishing executive, C.W. Henderson, CEO of NewsRx. Henderson said that delivering the...

Preclinical Testing of Therapeutic Compound Completed.
January 9, 2001... 2001 JAN 9 - (NewsRx.com & NewsRx.net) -- OraPharma, Inc. (OPHM), Warminster, Pennsylvania, reported the completion of preclinical testing in its oral mucositis program. The preclinical work has led to the identification of a lead...

Preliminary Results Show Thalidomide Effective.
January 9, 2001... 2001 JAN 9 - (NewsRx.com & NewsRx.net) -- The results of a Phase II trial have shown thalidomide to be effective in treating some men with androgen-independent prostate cancer. U.S. National Cancer Institute researchers reported these...

Non-Invasive Procedure Visualizes Real-Time Tumor Growth in Live Mice.
January 9, 2001... 2001 JAN 9 - (NewsRx.com & NewsRx.net) -- - by Sonia Bell-Nichols, staff medical writer -- Using a simple, non-invasive, imaging procedure, research scientists have been able to view real-time tumor growth in the brain, liver, bones, and other...

Genetic Transformation Converts Healthy Cells.
January 16, 2001... 2001 JAN 16 - (NewsRx.com & NewsRx.net) -- Cells originating from normal human breast tissue have been converted into breast cancer cells by a defined protocol of genetic changes. In the January 1, 2001, issue of Genes & Development, Dr....

Prophylactic Tamoxifen Has No Heart-Related Effects.
January 16, 2001... 2001 JAN 16 - (NewsRx.com & NewsRx.net) -- The breast cancer prevention drug, tamoxifen, does not influence cardiovascular risk in healthy women or in women with coronary heart disease, according to a study published in the January 3, 2001,...

Sub-Cellular Structure Discovered.
January 16, 2001... 2001 JAN 16 - (NewsRx.com & NewsRx.net) -- Does it take two spindles to tango during cell division? A group of scientists from Iowa State University doing research under a National Science Foundation (NSF) grant reports that they have...

Radiotherapy More Effective When Combined with Intracavitary Brachytherapy.
January 16, 2001... 2001 JAN 16 - (NewsRx.com & NewsRx.net) -- External radiotherapy used to treat early stage nasopharyngeal cancer (NPC) is more effective when supplemented with intracavitary brachytherapy, oncologists in Hong Kong report. P.M.L. Teo and...

Study Says Lymphocytic Infiltration is Beneficial.
January 16, 2001... 2001 JAN 16 - (NewsRx.com & NewsRx.net) -- Lymphocytic infiltration in undifferentiated nasopharyngeal carcinoma (NPC) is actually beneficial to the patient, reducing the chances of metastasis and even destroying some cancer cells, researchers...

Fibroblast Growth Factor and Its Receptors Common to Ovarian Tumors.
January 16, 2001... 2001 JAN 16 - (NewsRx.com & NewsRx.net) -- Fibroblast growth factor (FGF)-8, a growth factor known for its mitogenic properties, could be a marker for ovarian cancer due to its relatively common expression on ovarian cancer cells, according to...

Keratinocyte Growth Factor Differentiates Benign and Cancerous Tumors.
January 16, 2001... 2001 JAN 16 - (NewsRx.com & NewsRx.net) -- Medical investigators in England propose that benign prostatic hyperplasia (BPH) can be distinguished from prostate cancers by testing for a growth factor in the blood called keratinocyte growth...

Eight Cases Have Surfaced This Year In Nevada.
January 16, 2001... 2001 JAN 16 - (NewsRx.com & NewsRx.net) -- An eighth case of childhood leukemia this year has surfaced in this small rural town where the drinking water was found to contain twice as much arsenic as allowed by law, a newspaper reported. The...

Scans Aid in Diagnosis of Non-Small-Cell Lung Cancer.
January 16, 2001... 2001 JAN 16 - (NewsRx.com & NewsRx.net) -- Positron emission tomography (PET) scanning is much more accurate in determining how far lung cancer has spread than any other diagnostic technique, and should be the standard of care, according to a...

Smoking Triples Risk of a Common Type of Skin Cancer.
January 16, 2001... 2001 JAN 16 - (NewsRx.com & NewsRx.net) -- Smoking more than triples the risk of developing squamous cell carcinoma, one of the most common forms of skin cancer, researchers from The Netherlands have shown. A link between smoking and this...

Encapsulating Cancer Therapies.
January 16, 2001... 2001 JAN 16 - (NewsRx.com & NewsRx.net) -- A single injection of living drug "factories" can shrink tumors in mice by cutting off their blood supply, raising hopes for potentially less toxic cancer treatments in humans. Tumor cells, which...

Phase I Clinical Trial Initiated.
January 16, 2001... 2001 JAN 16 - (NewsRx.com & NewsRx.net) -- OSI Pharmaceuticals, Inc. (OSIP), Uniondale, New York, announced that Pfizer Inc. (PFE) has opened an IND for Phase I clinical trials in the United States to evaluate a small molecule anticancer drug...

Antisense Growth Factor Therapy Inhibits Metastatic Tumor Growth.
January 16, 2001... 2001 JAN 16 - (NewsRx.com & NewsRx.net) -- Antisense basic fibroblast growth factor (bFGF) gene therapy via adenoviral vector works on several levels in treatment of transitional cell carcinoma of the bladder, a study conducted in mice...

MIT Radar Technology Enters Phase II Trials.
January 16, 2001... 2001 JAN 16 - (NewsRx.com & NewsRx.net) -- An Massachusetts Institute of Technology (MIT) researcher's work on radar technology to detect missiles will be applied in U.S. Food and Drug Administration (FDA)-approved Phase II clinical trials for...

Scientists Associate Cancer with Growth Factor in Serum of Pre-Menopausal Women.
January 16, 2001... 2001 JAN 16 - (NewsRx.com & NewsRx.net) -- New research indicates that a hormone called insulin-like growth factor (IGF)-I is observed more often in pre-menopausal women with breast cancer than in same-aged women without breast cancer. The...

Angiogenesis Shut Down by Tamoxifen in Estrogen Receptor-Negative Tumors.
January 16, 2001... 2001 JAN 16 - (NewsRx.com & NewsRx.net) -- - by Sonia Bell-Nichols, staff medical writer -- Researchers at Duke University in North Carolina say that tamoxifen has proven effective as an anti-angiogenesis agent in tumors that are estrogen...

Basic Fibroblast Growth Factor Defeats Ewing's Sarcoma in Mice.
January 16, 2001... 2001 JAN 16 - (NewsRx.com & NewsRx.net) -- Basic fibroblast growth factor may be better known for its role in promoting cancer than stopping cancer, but new research shows that this growth factor could be of potential benefit as an anti-cancer...

Company to Accelerate Development of Antibody-Based Therapeutics.
January 16, 2001... 2001 JAN 16 - (NewsRx.com & NewsRx.net) -- Immunomedics (IMMU), Morris Plains, New Jersey, announced that the company is refocusing internal and certain external activities exclusively on its pipeline of cancer therapeutic antibodies. The...

Serotype G Chlamydia Strain Strongly Associated with Disease Development.
January 16, 2001... 2001 JAN 16 - (NewsRx.com & NewsRx.net) -- Women with the sexually transmitted infection Chlamydia trachomatis are at increased risk of developing cervical squamous cell carcinoma (SCC), and the risk is highest when the infection is serotype G,...

Grant Awarded to Develop Therapy Techniques To Enhance Tumor Cells Sensitivity.
January 16, 2001... 2001 JAN 16 - (NewsRx.com & NewsRx.net) -- Introgen Therapeutics, Inc. (INGN), Austin, Texas, announced that it was awarded a Small Business Technology Transfer (STTR) grant from the U.S. National Cancer Institute (NCI). The grant will...

Research Explores Recurrent Miscarriages, Hoping to Help Transplant and Cancer Patients.
January 16, 2001... 2001 JAN 16 - (NewsRx.com & NewsRx.net) -- A mother's immune system may attack a fetus from multiple fronts, by sending in killer T cells, by producing antibodies that target fetal cells, or by coating cells with a destructive, soluble blood...

Protectin (CD59) Regulates Susceptibility to Homologous Complement.
January 16, 2001... 2001 JAN 16 - (NewsRx.com & NewsRx.net) -- Overexpression of protectin (CD59), a glycosylphosphatidylinositol-anchored cell membrane glycoprotein that acts as a terminal regulator of complement (C) cascade, down-modulates the susceptibility of...

New Discovery Has Implications for Cancer, Other Diseases.
January 16, 2001... 2001 JAN 16 - (NewsRx.com & NewsRx.net) -- Cancer, cholesterol metabolism, and developmental disorders may soon be better understood because of surprising new information revealed in a study by researchers at Mount Sinai School of Medicine, New...

Vaccine Found Safe in Early Study.
January 16, 2001... 2001 JAN 16 - (NewsRx.com & NewsRx.net) -- Johns Hopkins University researchers say early tests of a pancreatic cancer vaccine show it is safe and successful in reaching immune system cells. A report on the findings was published in the...

Novel DNA-Binding Vectors Could Have Applications for Cancer Gene Therapy.
January 16, 2001... 2001 JAN 16 - (NewsRx.com & NewsRx.net) -- Pharmacology researchers at the University of Bath, England, have developed a series of polyamine-poly(ethylene glycol) constructs that could have use as non-viral vectors of gene therapies. S.W....

Genetic Instability Important Factor During Onset.
January 23, 2001... 2001 JAN 23 - (NewsRx.com & NewsRx.net) -- - by Michael Greer, staff medical writer -- Oncologists in Texas think that genetic instability is an important factor in the development of head and neck carcinomas, and not, as some have suggested, a...

Alkylglycerols Can Help Deliver Medication Past Blood-Brain Barrier.
January 23, 2001... 2001 JAN 23 - (NewsRx.com & NewsRx.net) -- Neurologists in Germany have shown that alkylglycerols can increase the permeability of the blood-brain barrier, allowing access for potentially life-saving antitumor medication. "The blood-brain...

Defect in Alpha-1 Antitrypsin Gene Increases Risk.
January 23, 2001... 2001 JAN 23 - (NewsRx.com & NewsRx.net) -- Mayo Clinic scientists have discovered that carriers of a genetic defect previously linked to emphysema have a three-fold increased risk of developing a type of sporadic colorectal cancer. ...

Fecal Blood Screens Reduce Incidence.
January 23, 2001... 2001 JAN 23 - (NewsRx.com & NewsRx.net) -- Regular screening of blood hidden in fecal matter for signs of colorectal cancer significantly reduces not only the chance of fatality from the disease, but the chance of malignancy arising in the...

Dermatologists Say Skin Biopsies Incorrect 33% of Time.
January 23, 2001... 2001 JAN 23 - (NewsRx.com & NewsRx.net) -- "Dermatologists who work in HMOs feel that one-third of the time the pathologist's diagnosis (of skin biopsies) may be incorrect," asserted a Columbia University professor. Bruce Katz, MD, added...

Analysis Fails to Link Angiogenesis with Epithelial Ovarian Carcinoma.
January 23, 2001... 2001 JAN 23 - (NewsRx.com & NewsRx.net) -- An analysis of angiogenesis markers and epithelial ovarian cancers has determined that there is no link between the two. The analysis, carried out on stage I through IV ovarian carcinomas, was...

Early Detection Would Save More Non-Hepatitis B and C Liver Cancer Patients.
January 23, 2001... 2001 JAN 23 - (NewsRx.com & NewsRx.net) -- Patients with non-hepatitis B or C related hepatocellular carcinomas would have better survival rates as compared with individuals with viral hepatitis related liver cancers if they could just become...

G Proteins Important for Regulating Growth and Proliferation of Cancer Cells.
January 23, 2001... 2001 JAN 23 - (NewsRx.com & NewsRx.net) -- Duke University medical researchers say G proteins play an important role in signaling mechanisms that control growth and proliferation in prostate cancer cells. In the Journal of Urology, P.F....

Patients Enrolled in Phase I Paclitaxel Formulation Study.
January 23, 2001... 2001 JAN 23 - (NewsRx.com & NewsRx.net) -- Sonus Pharmaceuticals, Inc. (SNUS) announced that patients are being enrolled in a Phase I clinical study with the company's first drug delivery product, S-8184, an injectable paclitaxel emulsion...

Favorable OvaRex Phase II Trial Results Reported.
January 23, 2001... 2001 JAN 23 - (NewsRx.com & NewsRx.net) -- AltaRex Corp. (AXO, ALRXF), Waltham, Massachusetts, reported the final results of one of its OvaRex Phase II trials conducted by Thomas Ehlen, MD, FRCSC, at the Vancouver Cancer Center in British...

Study Results Show Topical Photodynamic Therapy Effective Against Superficial Basal Cell Carcinoma.
January 23, 2001... 2001 JAN 23 - (NewsRx.com & NewsRx.net) -- PhotoCure ASA, London, United Kingdom, announced positive results from its first Phase III study on primary superficial basal cell carcinoma (BCC). In this study, more than 90% of the skin cancer...

Success Marred by Side Effects of Kidney Failure.
January 23, 2001... 2001 JAN 23 - (NewsRx.com & NewsRx.net) -- While there has been a dramatic increase in the use of bone marrow transplantation (BMT) to treat patients with cancer it has come at a high price. One of the major side effects of curing cancer...

Clinical Guidelines Updated to Options for Metastatic Disease.
January 23, 2001... 2001 JAN 23 - (NewsRx.com & NewsRx.net) -- The December 30, 2000, issue of Oncology highlights the updated National Comprehensive Cancer Network (NCCN) breast cancer treatment guidelines featuring a recently approved treatment option for...

Estrogen-Receptor-Positive Cancers Associated with LAR Phosphatase.
January 23, 2001... 2001 JAN 23 - (NewsRx.com & NewsRx.net) -- A new study conducted by researchers at the University of Rochester School of Medicine shows estrogen-receptor-positive tumors associate with the protein tyrosine phosphatase LAR. Several signal...

Tamoxifen Analogue Toremifene Not as Toxic to Liver.
January 23, 2001... 2001 JAN 23 - (NewsRx.com & NewsRx.net) -- The new drug toremifene, a drug with anti-estrogen activity similar to tamoxifen, does not cause as many liver-related disorders in breast cancer patients, according to new research. Fatty liver...

Investigational New Drug Application Filed for Dolastatin Analog.
January 23, 2001... 2001 JAN 23 - (NewsRx.com & NewsRx.net) -- Ilex Products Inc., announced January 3, 2001, that it had submitted an Investigational New Drug (IND) application to the U.S. Food and Drug Administration (FDA) to test the investigational drug...

Tumor-Specific Vaccines Under Development.
January 23, 2001... 2001 JAN 23 - (NewsRx.com & NewsRx.net) -- BioPulse International, Inc., (BIOP), San Ysidro, California, announced the development of multiple Tumor-Specific Cancer Vaccines (TSV). The vaccines are based on the company's dendritic cell...

Caveolin-1 Gene Transfer May Be Able to Reverse Cell Transformation.
January 23, 2001... 2001 JAN 23 - (NewsRx.com & NewsRx.net) -- Researchers in New York have shown that the transfer of caveolin-1 DNA to cells derived from squamous cell carcinomas can halt the growth of the malignant cells, a finding that may lead to the...

Replication Competent Adenovirus Can Enhance Transgene Expression During Therapy.
January 23, 2001... 2001 JAN 23 - (NewsRx.com & NewsRx.net) -- Researchers in Germany have shown that replication competent adenovirus (RCA) can induce the replication of therapeutic gene vectors in malignant cells, dramatically enhancing beneficial transgene...

Protein Opens Door for Transfer from Bacteria to Plants.
January 23, 2001... 2001 JAN 23 - (NewsRx.com & NewsRx.net) -- In the only known example of the transfer of genetic material between the plant and animal kingdoms, a tumor-inducing, single-stranded segment of DNA from the soil bacterium Agrobacterium tumefaciens...

Patent Issued for Measuring Quantity and Quality of DNA in Samples.
January 23, 2001... 2001 JAN 23 - (NewsRx.com & NewsRx.net) -- Exact Sciences Corporation, an applied genomics company developing screening technologies for the early detection of cancer, announced January 3, 2001, the issuance of its tenth U.S. Patent, No....

Therapeutic Target Discovered for Breast and Ovarian Cancer.
January 23, 2001... 2001 JAN 23 - (NewsRx.com & NewsRx.net) -- Immusol, Inc, San Diego, California, announced that the company's proprietary Inverse Genomics technology led to the discovery of a potential drug target gene for breast and ovarian cancer. ...

Apoptosis Study Reveals New Clues to Diagnosis and Treatment of Malignant Disease.
January 23, 2001... 2001 JAN 23 - (NewsRx.com & NewsRx.net) -- To explore alternative explanations for the origins and properties of malignant melanoma, and to identify potential targets and strategies for therapy, Scott Lowe and his colleagues at Cold Spring...

Idarubicine/Busulphan/Melphalan Conditioning Regimen Shows Promise for Stem Cell Transplants.
January 23, 2001... 2001 JAN 23 - (NewsRx.com & NewsRx.net) -- Oncologists in Italy have shown that a conditioning regimen for peripheral blood stem cell transplant consisting of high doses of idarubicine, busulphan, and melphalan results in low toxicity and rapid...

Schwann Cells Could be Determining Factor in Tumor Growth and Progression.
January 23, 2001... 2001 JAN 23 - (NewsRx.com & NewsRx.net) -- Schwann cells, commonly located in normal tissues and in some cancer tumors, tend to dampen the expression of growth factors that normally induce cell growth, proliferation, and angiogenesis in...

Ibritumomab Tiuxetan Under Evaluation for Lymphatic Cancers.
January 23, 2001... 2001 JAN 23 - (NewsRx.com & NewsRx.net) -- IDEC Pharmaceuticals Corporation announced January 2, 2001, that the Biologics License Application (BLA) for Zevalin(TM) (ibritumomab tiuxetan) has been accepted for filing by the U.S. Food and Drug...

Combination Therapy Effective But Risky.
January 30, 2001... 2001 JAN 30 - (NewsRx.com & NewsRx.net) -- - by Maryclaire Lindgren, staff medical writer -- A combination of high-dose rate intracavitary brachytherapy and external beam radiation therapy with 60 grays (Gy) or more of a total equivalent dose...

Fractionated Stereotactic Radiotherapy: A Good Choice for Local Control.
January 30, 2001... 2001 JAN 30 - (NewsRx.com & NewsRx.net) -- Fractionated stereotactic radiotherapy (FSRT) is effective for control of local acoustic neuromas, especially in patients with neurofibromatosis Type 2 (NF2). M. Fuss, of the University of Texas,...

Extended Neoadjuvant Chemotherapy Cycles Appear to Prolong Patient Survival.
January 30, 2001... 2001 JAN 30 - (NewsRx.com & NewsRx.net) -- Extended cycles of neoadjuvant chemotherapy appears to prolong survival in patients with locally-advanced breast cancer. The preliminary results of a five-year follow-up of 42 stage III patients...

Clinical Trial of Transfected Xenogeneic Cells Begins in Patients with Metastases.
January 30, 2001... 2001 JAN 30 - (NewsRx.com & NewsRx.net) -- Researchers in France have initiated a Phase I clinical trial of xenogeneic cells transfected with interleukin-2 (IL-2) in patients with metastatic tumors. "Various studies have emphasized an...