Cancer Weekly articles from January 1992

Cancer Weekly archives from January 1992

Research team creates genetic map of chromosome linked to breast cancer. (University of California at Los Angeles School of Medicine)
January 6, 1992... California An interdisciplinary team of researchers at the University of California at Los Angeles (UCLA) School of Medicine has significantly narrowed the location of the gene for a progressive neurologic disease of childhood called...

Study: x-rays may increase breast cancer risk for some. (ataxia-telangiectasia gene carriers) (University of North Carolina)
January 6, 1992... University of North Carolina X-rays - even in "appallingly low" doses - appear to trigger breast cancer in people who carry a particular gene that is present in more than one million American women, scientists said. "People who...

Scientists seek breast cancer prevention tools. (Texas)
January 6, 1992... Texas Licorice root, used for centuries in some countries to treat various maladies, is among the myriad of substances being investigated by Texas scientists looking for ways to prevent breast cancer. Elements of some promising new...

Study: urban hospitals may offer sub-standard breast cancer care. (Illinois)
January 6, 1992... Illinois Small Chicago hospitals that treat many poor patients may offer substandard breast cancer care because of limited financial resources, says the author of a study. The study, in the December 25, 1991, Journal of the American...

Scientist studies tannin as a potent cancer inhibitor. (Kansas State University researcher Jean-Pierre Perchellet)
January 6, 1992... Kansas Kansas State University (K-State) cancer researcher Jean-Pierre Perchellet has found that tannic acid, one of the chemicals in vegetable tannin, slows the growth of skin cancer tumors. After two years of research he is expanding...

Lung cancer mortality rates released. (U.S. Department of Health and Human Services)
January 6, 1992... U.S. Department of Health and Human Services U.S. Department of Health and Human Services (HHS) Secretary Louis W. Sullivan, M.D., released a U.S. National Cancer Institute (NCI) report indicating that lung cancer death rates among white...

Researchers urge tougher antismoking efforts. (New York)
January 6, 1992... New York Laws limiting smoking are effective, but higher tobacco taxes, job discrimination against smokers and other measures are needed to reduce tobacco use, cancer researchers said. In New York, taxes account for about one-third...

Expert: increased snuff use could lead to mouth cancer epidemic. (Elbert D. Glover) (West Virginia)
January 6, 1992... West Virginia When a 17-year-old must lose weight before a wrestling match, he puts wads of Copenhagen snuff between his cheek and gum. "It's a good substitute when you can't eat because you're trying to make your weight. I don't think...

Designation as a main institution of the Eastern Cooperative Oncology Group received. (Medical College of Wisconsin)
January 6, 1992... Medical College of Wisconsin The Medical College of Wisconsin (MCW) has been designated a main institution of the Eastern Cooperative Oncology Group (ECOG), a national organization involved in testing promising new cancer treatments. ...

Clinical trials initiated for imaging non-small cell lung cancer. (Cytogen Corporation)
January 6, 1992... Cytogen Corporation Cytogen Corporation reported the initiation of Phase I human clinical trials for a non-small cell lung cancer imaging product. The studies with OncoTc NSL380 (lung) will initially be conducted at three U.S....

Broad patent awarded for interleukin-1 receptor antagonist. (Synergen and University of Colorado)
January 6, 1992... Synergen and University of Colorado Synergen Inc. and the University of Colorado Foundation Inc. announced that they have obtained a U.S. patent on the DNA for interleukin-1 inhibitors and methods for the production of interleukin-1...

Rights acquired to prostate cancer antibodies. (Cytocare Inc.)
January 6, 1992... Cytocare Inc. Cytocare Inc., Irvine, California, has announced the acquisition of worldwide exclusive rights for diagnostic, prognostic and therapeutic uses of certain hybridoma cell lines and their prostate monoclonal antibodies. The...

Acquisition of U.S. rights to Thymosin alpha 1 from Hoffmann-La Roche completed. (Alpha 1 Biomedicals Inc.)
January 6, 1992... Alpha 1 Biomedicals Inc. Alpha 1 Biomedicals Inc. announced that it has completed the acquisition of all U.S. rights to Thymosin alpha 1 from Hoffmann-La Roche Inc., of Nutley, New Jersey. In September 1990, Alpha 1 Biomedicals...

New DNA sequencing technology in support of the human genome program. (research grant availability) (Research Report)
January 6, 1992... AUTHORS: RFA Available: HG-92-01. National Center For Human Genome Research. "Letter of Intent Receipt Date: January 31, 1992. Application Receipt Date: March 17, 1992. The National Center for Human Genome Research (NCHGR) announces...

Individual postdoctoral and senior fellowships in genomic analysis and technology and the ethical, legal and social implications of human genome research. (Research Report)
January 6, 1992... AUTHORS: PA: PA-92-21. National Center for Human Genome Research. "Purpose: The mission of the National Center for Human Genome Research (NCHGR) is to characterize the human genome and the genomes of selected model organisms. The...

Intraoperative radiotherapy - current status - 1991. (Research Report)
January 6, 1992... AUTHORS: Timothy J. Kinsella. University of Wisconsin Medical School, Madison, Wisconsin. According to the author's abstract of a presentation to the 33rd annual meeting of the American Society for Therapeutic Radiology and Oncology,...

Computer-controlled radiation therapy and 3-D treatment planning. (Research Report)
January 6, 1992... AUTHORS: Benedick Fraass and Allen S. Lichter. University of Michigan Medical Center, Ann Arbor, Michigan. According to the authors' abstract of a presentation to the 33rd annual meeting of the American Society for Therapeutic Radiology...

The EORTC radiotherapy group experience: Phase III trials in hyperfractionation (HF) and accelerated fractionation (AF) in head and neck cancers. (Research Report)
January 6, 1992... AUTHORS: Jean-Claude Horiot. Tumor Institute Center Georges-Francois Leclerc, Dijon, France. According to the author's abstract of a presentation to the 33rd annual meeting of the American Society for Therapeutic Radiology and...

Results of the Brain Tumor Study Group. (Research Report)
January 6, 1992... AUTHORS: Melvin Deutsch. University of Pittsburgh, Pittsburgh, Pennsylvania. According to the author's abstract of a presentation to the 33rd annual meeting of the American Society for Therapeutic Radiology and Oncology, held in...

Levamisole: known effects on the immune system, clinical results, and future applications to the treatment of cancer. (Periodical Report)
January 6, 1992... SOURCE: Journal of Clinical Oncology, November, 1991;9(11):2052-2066. Levamisole has proven disappointing in clinical trials involving advanced breast cancer, lung cancer, colorectal cancer, melanoma and lymphoproliferative disease, but...

Oral carmofur in advanced gastrointestinal cancer. (Periodical Report)
January 6, 1992... SOURCE: American Journal of Clinical Oncology, November/December, 1991;13(6):477-479. The fluorinated pyrimidine carmofur is active with acceptable toxicity in the ambulatory treatment of gastrointestinal malignancies, according to a...

Human IgM monoclonal antibody 16.88: pharmacokinetics and immunogenicity in colorectal cancer patients. (Periodical Report)
January 6, 1992... SOURCE: Journal of the National Cancer Institute, December 18, 1991;83(24):1813-1819. A study from The Netherlands found that human IgM monoclonal antibody 16.88 did not induce specific antibody response after repeated infusions of up...

Nonviral risk factors for hepatocellular carcinoma in a low-risk population, the non-Asians of Los Angeles County, California. (Periodical Report)
January 6, 1992... SOURCE: Journal of the National Cancer Institute, December 18, 1991;1820-1826. Cigarette smoking, alcohol consumption, and use of oral contraceptives are major risk factors for hepatocellular cancer among non-Asian residents of Los...

Prognostic significance of the expression of ras oncogene product in non-small cell lung cancer. (Periodical Report)
January 6, 1992... SOURCE: Cancer, January 1, 1992;69(1):72-78. Enhanced ras p21 expression may be one of the most important biologic and clinical markers of malignancy, according to a Japanese study. Although the relationship between the ras...

Impact of adjuvant radiation on the patterns and rate of relapse in advanced-stage Hodgkin's disease treated with alternating chemotherapy combinations. (Periodical Report)
January 6, 1992... SOURCE: Journal of Clinical Oncology, December, 1991;9(12):2193-2201. Residual microscopic disease frequently occurs in advanced Hodgkin's disease patients with apparent complete remission after alternating combination chemotherapy, and...

Researchers show p53 gene stops growth of childhood leukemia cells. (University of California, San Diego)
January 13, 1992... California In the first use of the p53 tumor suppressor gene against leukemia, University of California, San Diego (UCSD) researchers suppressed human T-cell acute lymphoblastic leukemia (T-ALL) growth and production, as tested in nude...

Suramin slows breast carcinoma. (National Institute for Medical Research, France)
January 13, 1992... France An in vitro study by Vignon et al., of the National Institute for Medical Research, Montpellier, France, shows that the drug suramin greatly inhibits the growth of estrogen receptor-positive (ER+) and estrogen receptor-negative...

Breast cancer study supports post-operative tamoxifen treatment. (London)
January 13, 1992... London The largest study of the treatment of early breast cancer confirms that the growing practice of combining hormonal and chemotherapy treatments gives patients a much greater chance of survival, scientists say. The study, a...

Need for psychological counselling identified for those at high risk for breast cancer. (Memorial Sloan-Kettering Cancer Center)
January 13, 1992... Memorial Sloan-Kettering Cancer Center There is a need for psychological intervention in women at high risk for developing breast cancer, in an effort to reduce distress, improve surveillance behaviors, and assure the earliest detection...

Agency faces decision on banning silicone gel implants. (U.S. Food and Drug Administration)
January 13, 1992... U.S. FDA The U.S. Food and Drug Administration (FDA) on January 6, 1992 called on doctors to stop using silicone gel breast implants until new information on their safety can be assessed. The FDA's action fell short of the outright...

Vitamins may lower colorectal cancer risk. (vitamins A, C, & E) (University of Bologna, Italy)
January 13, 1992... Italy Vitamins A, C, and E may reduce certain cell proliferation abnormalities in patients with adenomas, according to a study by Paganelli, et al., University of Bologna, Italy. Past observations have suggested that such abnormalities...

Prokine for treatment of bone marrow transplant engraftment failure approved. (U.S. Food and Drug Administration)
January 13, 1992... U.S. FDA Sargramostim, a yeast-derived granulocyte-macrophage colony stimulating factor, improves survival of cancer patients in whom myeloid engraftment is delayed or is lost after bone marrow transplantation. Based on study data...

Secondary lung cancer screening system developed. (University of Colorado)
January 13, 1992... Colorado A secondary screening for evaluation of new anticancer agents and therapies used to treat lung cancer may have clinical implications, according to University of Colorado researchers who developed and tested it. The new...

New evidence links increase in skin cancer to environment. (New York University Medical Center)
January 13, 1992... New York Dermatologists have long known that too many days under the sun can cause skin cancer. But now we have a new understanding of the situation. Researchers have discovered the unmistakable signs of genetic damage from...

Patent covering loading of cancer drugs granted. (The Liposome Co.)
January 13, 1992... The Liposome Co. The Liposome Co. Inc., Princeton, New Jersey, was granted a U.S. patent covering improved methods for encapsulating anticancer drugs in liposomes and the liposomal drugs made by these methods. The methods and...

Agency plans to ask FDA approval for five European drugs. (Aphidicoline glycinate, Bryostatin, Rhizoxin, Anthrapyrazol analogue, Temazolamide) (U.S. National Cancer Institute)
January 13, 1992... U.S. NCI The U.S. National Cancer Institute (NCI) will seek U.S. Food and Drug Administration (FDA) approval for five investigational new drugs (IND) from Europe. The drugs include Aphidicoline glycinate, tested through the...

Rabbits used successfully in study of HTLV-II virus. (Ohio State University)
January 13, 1992... Ohio State University At Ohio State University, rabbits are being used to study one of three retroviruses known to infect humans. The research is the first step in resolving whether the virus causes disease in humans. The...

Radon barrier tests under way. (Montana)
January 13, 1992... Montana The Lead Industries Association (LIA) announced that it is conducting further tests in Butte, Montana, as part of an ongoing program to determine the effectiveness of sheet lead as a barrier against radon, a colorless, odorless...

Eight states begin breast and cervical cancer screenings. (U.S. Centers for Disease Control)
January 13, 1992... U.S. CDC Sponsored by the U.S. Centers for Disease Control (CDC), eight states have begun a breast and cervical cancer screening project for low-income women that is expected to grow into a comprehensive nationwide program. ...

Tumor resistance to chemotherapy lecture scheduled. (U.S. National Institutes of Health)
January 13, 1992... U.S. NIH Michael M. Gottesman, M.D., will review progress in understanding tumor resistance to chemotherapy when he presents the U.S. National Institutes of Health (NIH) lecture, "Molecular Analysis of Resistance to Anticancer Drugs."...

Lieutenant governor announces plans for breast cancer legislation. (Leo McCarthy) (California)
January 13, 1992... California Cancer groups are hailing proposed legislation to declare breast cancer an epidemic in California as an essential first step in greater breast cancer awareness. "It's not a solution. It's an awareness-building tool,"...

Boron brain cancer treatment program's future in doubt. (Idaho National Engineering Laboratory)
January 13, 1992... Idaho National Engineering Laboratory A brain cancer treatment under research for the Idaho National Engineering Laboratory (INEL) received a holiday infusion of $400,000, but the future of the program remains cloudy. A few days...

Study of cancer incidence in Los Alamos undertaken. (New Mexico)
January 13, 1992... New Mexico Los Alamos, New Mexico, physician Jon Johnson was selected as chairman of a committee that will guide a New Mexico state Health Department study of cancer in Los Alamos County. Johnson was chosen by the steering committee...

Brain cancer patient sues utility, citing electromagnetic fields. (Connecticut)
January 13, 1992... Connecticut A brain cancer patient who believes living across the street from a power substation caused her disease is suing Northeast Utilities (NU). The patient, who is 19 years old, contends in the lawsuit filed January 6, 1992,...

Human test results encouraging, U.S. investors told. (Quadra Logic Technologies Inc.)
January 13, 1992... Quadra Logic Technologies Inc. Quadra Logic Technologies Inc. (QLT) continues to receive encouraging results from tests in its three core drug development programs, company officers reported. William J. Foran, recently named...

Combined modality therapy for the treatment of invasive bladder cancer. (Research Report)
January 13, 1992... AUTHORS: William U. Shipley. Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, Massachusetts. According to the author's abstract of a presentation to the 33rd annual meeting of the American Society for...

Breast-conservation and definitive irradiation for microinvasive ductal carcinoma of the breast. (Research Report)
January 13, 1992... AUTHORS: Lawrence J. Solin, Barbara L. Fowble, Delray J. Schultz and Robert L. Goodman. Fox Chase Cancer Center and the University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania. According to the authors' abstract of a...

Prognostic significance of tumor histology of recurrence in the treated breast after conservative surgery (CS) and radiation therapy (RT) for early-stage breast cancer. (Research Report)
January 13, 1992... AUTHORS: Anthony Abner, Abram Recht, Frank Vicini, Barbara Silver and Jay R. Harris. Harvard Medical School, Boston, Massachusetts. According to the authors' abstract of a presentation to the 33rd annual meeting of the American Society...

Optimal thoracic irradiation (TI) in the treatment of limited stage small-cell lung cancer (LSCLC). (Research Report)
January 13, 1992... AUTHORS: I. Hodson, P. Coy, N. Murray, J. Pater, A. Arnold, E. Kostashuk, P. Dixon, B. Zee, A. Sadura, J. Ayoub, M. Levitt, R. Wierzbicki, R. Feld, D. Payne, J. Maroun and K. Wilson. National Cancer Institute of Canada Clinical Trials Group....

Advances in a 3D radiation treatment planning system. (Research Report)
January 13, 1992... AUTHORS: J.A. Purdy, W.B. Harms, J.W. Matthews, R.E. Drzymala, J. Manolis and B. Emami. Washington University School of Medicine, St. Louis, Missouri. According to the authors' abstract of a presentation to the 33rd annual meeting of...

Inhibition of breast cancer growth by suramin. (Periodical Report)
January 13, 1992... SOURCE: Journal of the National Cancer Institute, January 1, 1992;84(1):38-42. The polyanionic compound suramin may be useful in the treatment of estrogen receptor-negative breast cancer patients who are insensitive to commonly used...

Clinical evaluation of intraperitoneal pseudomonas exotoxin immunoconjungate OVB3-PE in patients with ovarian cancer. (Periodical Report)
January 13, 1992... SOURCE: Journal of Clinical Oncology, December, 1991;9(12):2095-2103. Very high levels of immunotoxin can be delivered into the peritoneal cavity of women with ovarian cancer, but antibodies must be highly specific to tumor cells,...

Effect of vitamin A, C, and E supplementation on rectal cell proliferation in patients with colorectal adenomas. (Periodical Report)
January 13, 1992... SOURCE: Journal of the National Cancer Institute, January 1, 1992;84(1):47-51. Vitamin A, C, and E supplementation may be effective in reducing abnormalities in cell kinetics that indicate precancerous condition for colorectal cancer,...

The new International Federation of Gynecology and Obstetrics surgical staging and survival rates in early endometrial carcinoma. (Periodical Report)
January 13, 1992... SOURCE: Cancer, January 1, 1992;69(1):200-203. A University of New York study found no survival difference between endometrial cancer patients with various substages of surgical stage I disease, suggesting that the substaging system may...

Lung cancer histologic type and family history of cancer. (Periodical Report)
January 13, 1992... SOURCE: Cancer, January 1, 1992;69(1):86-91. A Louisiana State University study suggests an association between family history of lung cancer and histologic cell type of tumor, but study authors conclude that more research is needed to...

Report indicates children exposed to cigarette smoke more likely to be sick. (England)
January 20, 1992... England Children who are exposed to routine cigarette smoke are more likely to suffer from at least 50 different illnesses, including sudden infant death syndrome and adolescent meningitis, according to a recent report. Dr. Anne...

Diet related to colorectal adenoma in men. (Harvard Medical School)
January 20, 1992... Harvard Medical School It has been established that a diet high in saturated fat and low in fiber increases the risk of colorectal cancer. A study by Harvard Medical School researchers now suggests that the same diet increases the risk...

Melanoma subset often misdiagnosed as benign. (Columbia University)
January 20, 1992... Columbia University A significant number of melanomas are virtually impossible to diagnose clinically and may be mistaken for and treated as benign, according to a study reported by two researchers at New York's Columbia University. ...

Breast-conserving surgery and radiation therapy underutilized. (Fred Hutchinson Cancer Research Center)
January 20, 1992... Fred Hutchinson Cancer Research Center Breast-conserving surgery is not performed on the majority of women with stage I and II breast cancer as recommended by the U.S. National Institutes of Health (NIH), according to a Fred Hutchinson...

Many teens ignore dangers of suntanning, study finds.
January 20, 1992... Illinois Teenagers who need sunscreens the most - white affluent sun-worshippers - often neglect using them, especially if their parents failed to insist they do so as children, a new study says. Eighty-one percent of 220 teenagers...

Manipulating genes hold promise of curing many diseases. (U.S. National Institutes of Health)
January 20, 1992... U.S. NIH For decades, the idea of curing disease by mending or replacing a broken gene seemed possible only in science fiction. That's no longer the case. Gene therapy is moving rapidly from idea to laboratory to hospital bedside,...

Hospital to study controversial cancer drug. (using tamoxifen to prevent breast cancer in women with a family history of the disease) (California)
January 20, 1992... California Scripps Memorial Hospital in La Jolla, California, will take part in a controversial national trial of a drug that doctors hope will prevent breast cancer in healthy women at risk of the disease, officials announced. The...

Society responds to breast implant moratorium. (American Cancer Society)
January 20, 1992... American Cancer Society In the wake of the U.S. Food and Drug Administration's (FDA) ban on the use of silicone breast implants, the American Cancer Society, Florida Division, is urging the medical community to take action toward...

Company must pay medical bills related to second-hand smoke in workplace. (Indiana)
January 20, 1992... Indiana Small businesses may have to reconsider smoking policies after the Indiana Workers Compensation Board ordered an employer to pay the medical bills of a woman whose health declined after breathing second-hand smoke in the...

Immunomedics Inc. receives approval for testing cancer imaging agent. (ImmuRAID-CEA) (Canada)
January 20, 1992... Canada Immunomedics Inc. announced that it has received approval from the biological and radiopharmaceutical sections of the Health Bureau Protectorate in Canada to commence the clinical trials for the company's colorectal cancer imaging...

Eurocetus receives approval to market OncoScint CR103 in Spain.
January 20, 1992... Spain EuroCetus B.V., a Chiron company, has announced that OncoScint CR103, a monoclonal antibody-based imaging agent for colorectal cancer, has received marketing approval in Spain. The approval follows the previous recommendation...

Company pursues new cancer therapy. (Immunomedics Inc.)
January 20, 1992... Immunomedics Inc. Immunomedics Inc. has announced that the U.S. Patent Office has allowed a patent application for the company's new method of cancer treatment combining radioactive cancer-seeking monoclonal antibodies with certain...

Company initiates clinical trials for imaging breast cancer. (OncoTc BR380) (Cytogen Corporation)
January 20, 1992... Cytogen Corporation Cytogen Corporation reported the initiation of Phase I human clinical trials for OncoTc BR380, the company's breast cancer imaging product. Breast cancer is the leading cancer in the United States, according to...

Company begins Betafectin Phase I clinical trials. (Alpha-Beta Technology)
January 20, 1992... Alpha-Beta Technology Alpha-Beta Technology Inc. announced that the company has started Phase I clinical trials with Betafectin, a carbohydrate-based compound under development for the prevention and treatment of infections related to...

Company receives use patent for GM-CSF. (granulocyte macrophage colony stimulating factor) (Immunex Corp.)
January 20, 1992... Immunex Corp. Immunex Corp. received a U.S. patent covering methods for priming human macrophage cells to have antitumor activity by administering granulocyte macrophage colony stimulating factor (GM-CSF), the company announced. ...

Unique and selective stimulation of immune system found with IVET-629. (InnoVet Inc.)
January 20, 1992... InnoVet Inc. InnoVet Inc. has announced the results of a study conducted by a major university with the IVET-629 immune stimulant. The study concludes that IVET-629 exhibits selective stimulation of B-lymphocytes, a unique property...

Approval received to market new products. (Duragesic fentanyl transdermal system) (Alza Corp.)
January 20, 1992... Alza Corp. Dr. Janice E. Shaw announced that the Alza Corp.-developed Duragesic fentanyl transdermal system, a transdermal patch used in the treatment of cancer pain and marketed in the United States by Janssen Pharmaceutica Inc., has...

Congressman Sanders proposes national cancer registry. (Bernard Sanders) (Vermont)
January 20, 1992... Vermont Representative Bernard Sanders, Independent-Vermont, says a nationwide cancer information gathering network may be the key to figuring out why New England has among the highest incidents of breast cancer. "Breast cancer in...

Interactive Research Project Grants for cancer. (National Cancer Institute research grant announcement) (Research Report)
January 20, 1992... AUTHORS: PA: PA-92-29. U.S. National Cancer Institute. "Application Receipt Dates: February 1, June 1, and October 1. Purpose: Complex questions in cancer research often require investigative efforts that extend beyond the level...

Estrogen replacement therapy in women with breast cancer: survey of patient attitudes. (Research Report)
January 20, 1992... Interactive Research Project Grants for Cancer AUTHORS: Rena Vassilopoulou-Sellin and Cynthia Zolinski. The University of Texas M.D. Anderson Cancer Center, Houston, Texas. According to the authors' abstract of a presentation to...

Mixed glial tumors of the central nervous system: excellent outcome with surgery. (Research Report)
January 20, 1992... Mixed Glial Tumors of the Central Nervous System: AUTHORS: M.M. Chintaqumpala, D. Armstrong, W. Cheek, J. Laurent and D.H. Mahoney. Baylor College of Medicine, Houston, Texas. According to the authors' abstract of a presentation to...

Hepatitis C infection in children with cancer. (Research Report)
January 20, 1992... AUTHORS: Leslie Lace, Naomi J. Winick and George R. Buchanan. University of Texas Southwestern Medical Center at Dallas and Children's Medical Center, Dallas, Texas. According to the authors' abstract of a presentation to the annual...

Cisplatin-induced peripheral neurotoxicity is dependent on total-dose intensity and single-dose intensity. (Periodical Report)
January 20, 1992... Hepatitis C Infection in Children with Cancer SOURCE: Cancer, January 1, 1992;69(1):203-207. Single-dose intensity as well as total-dose intensity are important in cisplatin-induced peripheral neurotoxicity, suggesting that the...

Relationship of prediagnostic serum levels of dehydroepiandrosterone and dehydroepiandrosterone sulfate to the risk of developing premenopausal breast cancer. (Periodical Report)
January 20, 1992... Relationship of Prediagnostic Serum Levels of SOURCE: Cancer Research, January 1, 1992;52:1-4. A Johns Hopkins University study suggests that high dehydroepiandrosterone levels are protective against breast cancer in premenopausal...

High serum lactate dehydrogenase level as a marker for drug resistance and short survival in multiple myeloma. (Periodical Report)
January 20, 1992... SOURCE: Annals of Internal Medicine, December 15, 1991;115(2):931-935. Elevated lactate dehydrogenase level is a predictor of a poor prognosis in selected multiple myeloma patients, and this group of patients should be considered for...

Necrosis and inhibition of growth of human lung tumor by anti-alpha-human chorionic gonadotropin antibody. (Periodical Report)
January 20, 1992... SOURCE: Journal of the National Cancer Institute, January 1, 1992;84(1):42-47. A Harvard University animal study suggests that anti-alpha-human chorionic gonadotropin antibody inhibits the growth of human lung tumors. ...

A pilot trial of chemohormonal therapy for metastatic prostate carcinoma. (Periodical Report)
January 20, 1992... SOURCE: Cancer, January 1, 1992;69(1):213-218. The combination of total androgen blockade plus carboplatin with androgen priming initiated responses in 11 of 15 metastatic prostate cancer patients entered in a Walter Reed Army Medical...

Diagnosis of nasopharyngeal carcinoma by DNA amplification of tissue obtained by fine-needle aspiration. (Periodical Report )
January 20, 1992... SOURCE: The New England Journal of Medicine, January 2, 1992;326(1):17-21. Fine-needle aspiration can provide sufficient tissue for diagnosis of nasopharyngeal cancer by DNA amplification of Epstein-Barr virus genomes, according to a...

Phase I-II trial of erythropoietin in the treatment of cisplatin-associated anemia. (Periodical Report)
January 20, 1992... SOURCE: Journal of the National Cancer Institute, January 15, 1992;84(2):98-103. Recombinant human erythropoietin (epoetin) significantly reduces treatment-related anemia seen in patients receiving the chemotherapy with cisplatin, and a...