Cancer Weekly articles from February 2004

Cancer Weekly archives from February 2004

Wound-healing genes influence cancer progression.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Genes that help wounds heal are most often the "good guys," but a new study paints them as the enemy in some types of cancer. Researchers at the Stanford University School of Medicine have found...

Hormone therapy leads to high rates of osteoporosis in men.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Androgen modulators used in the treatment of prostate cancer can lead to severe bone loss in men, but early intervention based on x-ray and bone mineral density scans may reduce the risk of fracture and...

Side effects make physicians, patients reluctant to use tamoxifen for DCIS.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Physicians and patients alike are reluctant to use tamoxifen, an adjuvant therapy in the treatment of the very earliest form of breast cancer - ductal carcinoma in situ (DCIS) - because of its side...

Telomerase is a major regulator of leukemia cell growth.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Telomerase is a major regulator of leukemia cell growth. According to recent research published in the journal Leukemia, "telomeres play an important role in the proliferation and senescence of...

Novel technique may help detect certain squamous cell cancers.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Researchers may be able to detect head and neck squamous cell cancer (HNSCC) earlier by testing for newly discovered signature protein patterns found in patients with this cancer, according to new...

Syndecan-1 may be a prognostic marker in intrahepatic cholangiocarcinoma.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Weak expression of syndecan-1 was predictive or poor prognosis after surgical resection, researchers report. "Syndecan-1, a cell-surface transmembrane heparin sulfate pro-teoglycan, has been...

Minnesota health department changes language on website.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- The Minnesota Department of Health said on January 12, 2004, it will modify language on its website that suggested abortion increases the risk of breast cancer. The Minnesota Medical Association...

Inorganic arsenic therapies may have toxic side effects.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Inorganic arsenic therapies may have toxic side effects. According to published research from the United States, "trivalent inorganic arsenic (arsenite, arsenic trioxide, As (III) is currently...

Lamivudine prevents rituximab-induced hepatitis B virus reactivation.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Lamivudine prevents rituximab-induced hepatitis B virus reactivation. According to researchers in Japan, "we used regimens containing rituximab in the treatment of five hepatitis B virus surface...

Cisplatin does not directly effect mitochondrial oxygen consumption.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Study finds that exposures to alkylating agents and anthracyclines produce immediate and dose-dependent impairment of mitochondrial oxygen consumption. According to recent research published in the...

CD105/endoglin is a marker for endometrial cancer angiogenesis.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- CD105/endoglin is a marker for endometrial cancer angiogenesis. "Angiogenesis is a key process in tumor growth and metastasis, and factor-VIII microvascular density has been found to influence...

Karyometry can detect abnormalities in normal urothelium near carcinoma.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Study finds that karyometry can detect an abnormal chromatin pattern and distribution in the normal-looking urothelium adjacent to papillary carcinoma. According to a study from Italy, "This study...

A 10-degree reverse Trendelenburg position can reduce pressure during craniotomy.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- During craniotomy, a 10-degree reverse Trendelenburg position rapidly reduces subdural pressure and dural tension reducing cerebral perfusion pressure (CPP). "Recently we studied the effect of...

Gliadel prolongs survival and time to relapse in some glioma patients.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Study finds that Gliadel improves survival and time to relapse, and that possibly expanding the indications for its use should be investigated. According to recent research from Scotland, "The...

Idarubicin unlikely to be used for treating primary CNS tumors.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Study results indicate that it is unlikely that Idarubicin (IDA), daunomycin, or other related anthracyclines will be useful for treating primary CNS tumors," researchers say. "IDA, the 4-demethoxy...

Anthracyclines activate antiapoptotic phosphorylation in breast cancer.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Studies support the ability of anthracyclines to activate antiapoptotic p44/42-MAPK phosphorylation in breast cancer, possibly via the novel mechanism of repression of MKP-1 transcription. ...

Beta[subscript]3 integrin expression can lead to increased tumor cell aggressiveness.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Study suggest that increased expression of the alpha[subscript]vbeta[subscript]3 integrin during breast cancer progression can result in increased tumor cell aggressiveness. "Osteopontin (OPN) is a...

Breast cancer resistance protein is a MTX and MTX-polyglutamate transporter.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Study data show that that breast cancer resistance protein (BCRP) is a methotrexate (MTX) and MTX-polyglutamate transporter and reveal a possible mechanism by which it confers resistance. According...

Dragon-boat racing helps heal cancer survivors in Singapore.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Dragon-boat racing was hardly the hobby that friends and family expected Kate Wong, 62, to pick up just months after undergoing surgery for breast cancer. "At your age?" Kate recalled her friends...

Increased breast cancer risk may be related to the HLA class III subregion.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Study results show a potential role of the HLA class III subregion in susceptibility to breast cancer. According to a study from Netherlands, "BRCA1 and BRCA2 germline mutations account for ...

NSAIDs may have chemopreventive effect against breast cancer.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Preliminary results from the Women's Health Initiative (WHI) indicate that regular use of aspirin, ibuprofen, or other NSAIDs may have a significant chemopreventive effect against breast cancer. ...

Nematode finding could shed light on BRCA1-involved cancers.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Our common evolutionary heritage with the humble nematode worm is helping unravel one of the key genetic puzzles in breast cancer. For the first time, Cancer Research UK researchers have found a...

Noninvasive treatment technique uses space-based technology.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- A novel noninvasive system for cancer treatment is being developed with technology from the European space industry. The first target for this new treatment, which could be ready as early as 2006,...

P1 homozygosity may be a potential risk factor in breast carcinogenesis.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Research suggests that P1 homozygosity could possibly be a risk factor in breast carcinogenesis. According to a study from Greece, "H-ras is a member of the ras superfamily of genes. This gene...

Pooled analysis of LOH in breast cancer finds many nonreproducible results.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Researchers compile a database of loss of heterozygosity (LOH) studies of breast cancer that lays a framework for further investigation. "Somatic loss of heterozygosity (LOH) has been widely...

Researchers study familial and early onset breast cancer in African Americans.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- In order to identify the spectrum of BRCA2 mutations in African Americans, researchers investigated breast or ovarian cancer patients from 74 independent families at elevated risk of germline mutations....

Risk differs among specific ethnic subgroups of South Asian women in U.K.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Cancer Research UK scientists have discovered that the risk of breast cancer among South Asian women in Britain differs according to their specific ethnic subgroup. Published in the January 6,...

Sequential drugs followed by TRAIL may be a new therapeutic approach for cancer.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Researchers report that sequential administration of chemotherapeutic drugs followed by TRAIL may be an effective new therapy for cancer. "According to published research from the United States,...

Steroid hormone-resistant breast cancer can be sensitive to growth factors.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Researchers establish numerous regulatory links between signal transduction pathways elicited by peptide growth factors and progesterone receptors (PR). "Breast cancers often have increased...

Ultrasound detects many microcalcifications in comedo-type intraductal carcinoma.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- More than 60% of microcalcifications in comedo-type intraductal carcinoma can be demonstrated by ultrasound, researchers say. According to published research from Taiwan, "The purpose of this study...

Underarm cosmetics with estrogen may contribute to breast cancer.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Further work is needed to determine whether the use of underarm cosmetics (particularly containing estrogenic formulants) contributes to the rising incidence of breast cancer. "A recent review by...

Many BRCA1 and BRCA2 genes mutations are unique to Spain.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Knowledge about the spectrum of BRCA1 and BRCA2 mutations will improve the detection strategy in countries with large Spanish populations, researchers say. According to published research from...

Kahalalide F preferentially induces cell death via oncosis in tumor cells.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Study show that Kahalalide F (KF) induces cell death via oncosis preferentially in human and prostate cancer cell lines. According to a study from Spain, "Kahalalide F is a novel antitumor drug of...

Liver metastases from unknown primary site are shown by MR imaging.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Liver metastases from unknown primary site are often multiple and often hypervascular, however no correlation with the histologic subtype was possible by MRI imaging. "According to recent research...

Researchers use and advocate SRS3xGado scans for cerebral radiosurgery.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Researchers say the identification of additional lesions with SRS3xGado MR may have implications for patients who are treated with stereotactic radiosurgery alone. "We investigated how frequently...

Type 1 diabetes increases cancer risk.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- A population-based cohort study in Sweden revealed that type 1 diabetes increases the risk of several types of cancer. According to recent research from Sweden, "Although patients with type 2...

Canstatin-N fragment stops endothelial cell proliferation and tumor growth.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Canstatin-N fragment stops endothelial cell proliferation and tumor growth. "Type IV collagen is one of the components of vascular basement involved in regulation of angiogenesis. Canstatin, the...

Computerized clinical reminders are helpful for physician prescribing behavior.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Study finds that clinical reminders to physicians helped patients receive treatment with erythropoietin. "The objective of this study is to examine the impact of a clinical reminder generated by an...

Data shows CF101 to be effective in restraining growth of certain cancers.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Can-Fite BioPharma announced new preclinical study results, published in three peer reviewed, high score scientific journals: the Journal of Biological Chemistry, the British Journal of Cancer, and...

Enrollment complete for phase II clinical study in non-Hodgkin lymphoma.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Favrille, Inc., has completed enrollment for its current phase II clinical trial (FavId-04) with the company's lead investigational agent, FavId. This agent is under clinical development for the...

FLAG[+ or -]Ida suitable for induction chemo in high-risk leukemia, MDS patients.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- FLAG[+ or -]Ida is safe and effective as induction chemotherapy in high-risk leukemia and MDS patients. According to recent research from England, "The combination of fludarabine (FDR), high dose...

Fusion proteins steer tumor necrosis factor-alpha to tumor blood vessels.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Fusion proteins steer tumor necrosis factor-alpha to tumor blood vessels. According to researchers writing in the journal Blood, "we sought to enhance the selective toxicity of tumor necrosis factor...

Granulocyte colony-stimulating factor reduces complications in elderly patients.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Further research studies are needed to identify the elderly patients who will benefit most from prophylactic granulocyte colony-stimulating factor (G-CSF). "According to recent research from Italy,...

Standard chemotherapies target specific sectors of the angiogenic cascade.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Standard chemotherapies target specific sectors of the angiogenic cascade. According to a study from Sweden, "tumors are angiogenesis dependent. Some chemotherapeutics have been shown to be able to...

Tumor cells plus adjuvant induced immunity against hepatoma.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Fixed tumor cells in combination with adjuvant induced protective antitumor immunity in a murine hepatoma model. According to recent research published in the journal Cancer Letters, "We previously...

Arsenic accumulates in mouse organs after repeated oral exposure.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Murine study finds that tissue accumulation of arsenic after repeated oral exposure to arsenate in the mouse corresponds to the known human target organs for arsenate-induced carcinogenicity. ...

Arsenite boosts the expression of proliferation factors in prostate cancer cells.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Arsenite boosts the expression of proliferation factors in prostate cancer cells. According to recent research published in the journal Molecular and Cellular Biochemistry, "arsenite is ubiquitous...

Riddelline is toxic and carcinogenic in rats and mice.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Study demonstrates the toxicity and carcinogenicity of riddelline in rats and mice. "These investigations of riddelliine analyzed potential carcinogenesis and the utility of the...

Evidence identifies the role of potassium homeostasis in apoptosis.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Studies of K+ regulation of apoptosis may lead to novel therapeutic strategies for apoptosis-related diseases, researchers report. According to recent research from the United States, "Programmed...

Jellyfish proteins help researchers see tumor suppression, live.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- The tumor-suppressor protein p53 guards cells against damage to their genetic material. When the protein is missing or mutated, cells tend to become cancerous. In the February 2004 issue of Nature...

Kaiser to routinely offer new DNA testing for cervical cancer in northern California.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Kaiser Permanente will routinely offer hundreds of thousands of women in northern California newly approved DNA testing to more accurately predict which women are at risk of developing cervical cancer....

Screening strategies of cervical cancer high-risk region compared.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Highly accurate screening for cervical cancer and cervical intraepithelial neoplasia grade 3 (CIN 3) is now technically feasible, but the remaining vital issue is to extend improved cervical cancer...

IND filed for phase I/II trial of MagneTarg system to deliver mitomycin C.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- FeRx, Inc., a targeted drug delivery company, announced that the U.S. Food and Drug Administration has allowed the phase I/II clinical trial submitted in an investigational new drug (IND) application...

Keynote address on Xyotax delivered at polymer therapeutics meeting.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- At the 6th International Symposium on Polymer Therapeutics in Cardiff, Wales, Cell Therapeutics, Inc., (CTIC, CTI) was honored with a keynote presentation on Xyotax, CTI's drug candidate that links...

Tocosol Paclitaxel anticancer drug receives third patent.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Sonus Pharmaceuticals, Inc., (SNUS) has been awarded a third United States patent, No. 6,667,048, covering the composition of Tocosol Paclitaxel, the company's lead cancer product. Paclitaxel, the...

ImClone gets $5 million payment relating to approval of ERBITUX in Switzerland.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- ImClone Systems, Inc., (IMCL) has achieved a milestone in its license agreement with Merck, KgaA, for development of ERBITUX outside of North America. The milestone relates to the approval in...

Alliance with M.D. Anderson to develop new cancer drugs announced.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Cetek Corporation and The University of Texas M.D. Anderson Cancer Center announced that they have signed a collaborative agreement to discover and develop new drugs targeting cancer and inflammatory...

Biotech enters partnership with Institute for Cancer Prevention to fight cancer.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Integrated BioPharma, Inc., (INB) has entered into a collaborative agreement with The Institute for Cancer Prevention, Inc., (IFCP). INB and IFCP will jointly research, develop, and test compounds...

Myriad Genetics agreement to include pharmacogenetics.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Myriad Genetics, Inc., (MYGN), and Abbott Laboratories, Inc., (ABT) have expanded their strategic alliance to include a broad new pharmacogenetics program. The research collaboration will focus on...

Disease specific, quality-of-life questionnaires may help cancer patients.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Researchers develop a disease specific questionnaire for use along with a core quality-of-life (QoL) questionnaire. "According to published research from England, "The need for disease-specific...

Eloxatin becomes a cornerstone therapy in Europe.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Sanofi-Synthelabo announced that Eloxatin, already indicated as a first line treatment of metastatic colorectal cancer in major European countries, has successfully completed a Mutual Recognition...

Silibinin may be useful in colon cancer prevention and intervention.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Silibinin may have efficacy as a cell cycle regulator and apoptosis inducer in human colon carcinoma, researchers report. "Silymarin, a defined mixture of natural flavonoid, has recently been shown...

U.K. diagnostic services will not cope with national bowel cancer screening role.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- U.K. Services for diagnosing gut disorders, which are already overstretched, would sink beneath the increased demands posed by a national bowel cancer screening program, suggests a new study. ...

Clinical trial initiated for colorectal cancer antitumor compound.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Pro-Pharmaceuticals, Inc., (PRW) announced the initiation of a phase II clinical study of its lead carbohydrate compound Davanat with 5-Fluorourcil (5-FU) in refractory colorectal cancer patients. ...

Company responds to reports of phase II VELCADE colorectal trial closure.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Millennium Pharmaceuticals, Inc., (MLNM) clarified that based on the completion of a prespecified interim analysis, the company has decided to stop further accrual to its phase II trial examining the...

Gamma tocopherol may be a potent colorectal cancer chemopreventive agent.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Researchers review the rationale supporting the development of gamma-tocopherol as a colorectal cancer preventive agent. "According to published research from the United States, "Nutritional...

Health plans can improve colorectal cancer screening rates.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Provider organizations (PO) may be able to improve colorectal cancer (CRC) screening rates and, thus, have a major public health impact, researchers say. According to recent research from the...

Virtual endoscopy using CT scan may be a tool in future cancer screening.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- CT colonography appears promising for future screening for colorectal cancer, researchers say. "The term virtual endoscopy refers to using either spiral computed tomography (CT colonography) or...

Company announces reimbursement for capsule endoscopy primary procedure.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Given Imaging (GIVN) announced that the Medicare carrier for the states of Ohio and West Virginia - Palmetto GBA - approved reimbursement coverage for capsule endoscopy as a primary procedure in the...

Regulating folate receptors during folate deficiency.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Folate, a type of B vitamin, is important in DNA synthesis, and folate deficiency can lead to fetal abnormalities in spinal cord and brain development. Folate receptors (FRs) have been shown to mediate...

Study suggests more cancer patients receiving aggressive care at end of life.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- A growing number of cancer patients are receiving aggressive treatments when they are near death, according to a study led by researchers at Dana-Farber Cancer Institute. "Our research has shown...

Cadmium carcinogenesis occurs via up-regulation of translation factors.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Up-regulation of the expression of translation factors is a novel molecular mechanism for cadmium carcinogenesis. "The molecular mechanisms potentially responsible for cadmium carcinogenesis were...

Study proposes surgical approach to invasive cancer of the distal esophagus.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Researchers discuss surgical approaches to distal invasive esophageal adenocarcinoma, which focus on the technical and functional aspects. "Barrett's carcinoma, usually arising in the distal...

Cancer drug discovery company announces public offering of common stock.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- NeoPharm, Inc., (NEOL) plans to offer 3,500,000 shares of its common stock in an underwritten public offering under its existing shelf registration statement. The company also intends to grant an...

$6.5M in funding to advance device technology.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Vivant Medical, Inc., announced the completion of a $6.5 million equity financing. The round was led by California Technology Ventures, joining existing investors Adams Street Partners, Johnson &...

Bone disease biotech company closes $1.6M financing.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Auxeris Therapeutics, Inc., a biopharmaceutical company focused on the development and commercialization of medicines to treat a broad range of bone diseases, announced the completion of a $1.6M...

Farm-raised salmon presents greater health risks than salmon from the wild.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Consuming farm-raised salmon may pose a greater health risk than eating salmon caught in the wild, according to a group of Cornell scientists. "It appears that the feed used for the farm-raised...

Researchers review surgically treated gastric cancer in the U.S., 1988-2000.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Regionalizing surgery for gastric cancer may improve mortality rates. "The incidence of gastric cancer and the need for subsequent surgery has been decreasing in the United States. However, very few...

Both roxatidine and cimetidine exert an antiangiogenic effect on colon cancer.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Both roxatidine and cimetidine exert an antiangiogenic effect on colon cancer. According to recent research from Japan, "cimetidine is known to suppress the growth of several tumors, including...

Nuclear factor kappaB inhibition impairs pancreatic cancer angiogenesis.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Nuclear factor kappaB inhibition impairs pancreatic cancer angiogenesis. According to recent research from the United States, "the effect of blockade of nuclear factor kappaB (NF-kappaB) activity on...

PET scans superior in revealing response to treatment for GISTs.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- In fighting cancer, the sooner doctors can determine how a patient will respond to a particular therapy, the more effective overall treatment will be. Researchers have now shown that 18F-FDG PET scans...

U.S. patents issued for gene delivery technologies.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Vical Incorporated (VICL) announced the issuance of U.S. Patent No. 6,673,776, covering novel methods of using DNA to deliver biologically active proteins, and U.S. Patent No. 6,670,332, covering a...

Iressa phase II trial data published.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- New data published in the Journal of Clinical Oncology (JCO) highlight the first phase II clinical trial of Iressa (gefitinib) Tablets in patients with recurrent glioblastoma. Glioblastoma is the...

Scientific journal reports on ZFP repression of VEGF-A.
February 3, 2004... 2004 FEB 3 - (NewsRx.com & NewsRx.net) -- Sangamo BioSciences, Inc., (SGMO) reported on the publication of an article entitled "Repression of Vascular Endothelial Growth Factor A in Glioblastoma Cells Using Engineered Zinc Finger Transcription...