Cancer Weekly articles from February 2000

Cancer Weekly archives from February 2000

Finding of Two Different Forms of Disease Could Change Treatment.(Brief Article)(Statistical Data Included)
February 1, 2000... 2000 FEB 1 - (NewsRx.com) -- In a ground-breaking study, researchers from Mount Sinai Hospital's Samuel Lunenfeld Research Institute and the University of Toronto have confirmed that there are two very different forms of colorectal...

Adenovirus Gene Transfer Safe to Primate Parotid Glands.(Brief Article)(Statistical Data Included)
February 1, 2000... 2000 FEB 1 - (NewsRx.com) -- Adenovirus-mediated transfer of the human aquaporin-1 cDNA to irradiated parotid glands of non-human primates was deemed safe, reported researchers from the United States. "This study evaluated the safety...

TUNEL Technique More Effective Method for Measuring Sunburn.(Brief Article)(Statistical Data Included)
February 1, 2000... 2000 FEB 1 - (NewsRx.com) -- Researchers in Japan have determined a technique for quantitative analysis of sunburn cell (apoptotic cell) formation that appears to be more useful than previous methods. Two types of epidermal cells,...

Chromosome 9 Monosomy by FISH Predicts Tumor Recurrence.(Brief Article)(Statistical Data Included)
February 1, 2000... 2000 FEB 1 - (NewsRx.com) -- Chromosome 9 monosomy by fluorescence in situ hybridization (FISH) can be used to predict the recurrence of bladder tumors, researchers say. Bladder irrigation specimens can be used to detect recurrent...

Catheterized Patients Require Careful Management.(Brief Article)(Statistical Data Included)
February 1, 2000... 2000 FEB 1 - (NewsRx.com) -- Patients undergoing Hickman-Broviac catheterization require careful monitoring for the development of bloodstream infections, according to a recent report. Patients frequently experience infectious...

Antibody Targeting Facilitates Gene Transfer to RCC Cells.(Brief Article)(Statistical Data Included)
February 1, 2000... 2000 FEB 1 - (NewsRx.com) -- Antibody-mediated targeting facilitates gene transfer to renal cell carcinoma (RCC) cells in vitro, reported a study from France. "Specific gene transfer into targeted tumor cells remains a critical issue...

Bcl-2 Gene Transfer Delays Androgen-Independent Progression.(Brief Article)(Statistical Data Included)
February 1, 2000... 2000 FEB 1 - (NewsRx.com) -- Bcl-2 gene transfer using antisense bcl-2 oligodeoxynucleotides delays androgen-independent progression and enhances chemosensitivity in prostate cancer, reported a study from Canada. "Bcl-2 expression is...

Study Finds Similar Behavior Between Pleomorphic Carcinoma and Carinosarcoma.(Brief Article)(Statistical Data Included)
February 1, 2000... 2000 FEB 1 - (NewsRx.com) -- Carcinosarcoma has been histogenetically linked to pleomorphic carcinoma. Now it appears they may behave in a similar manner, according to researchers. M. N. Coss and colleagues at the Armed Forces...

MAC-Related Tumor Mimics Meningioma.(Brief Article)(Statistical Data Included)
February 1, 2000... 2000 FEB 1 - (NewsRx.com) -- A Mycobacterium avium complex-related tumor mimicking meningioma was reported by researchers at the University of California at Los Angeles. Intracranial tuberculomas manifesting radiologically as typical...

Human Papillomavirus Associated with Secondary Neoplastic Lesions.(Brief Article)(Statistical Data Included)
February 1, 2000... 2000 FEB 1 - (NewsRx.com) -- Researchers in Norway have demonstrated the presence of human papillomavirus (HPV) 16 in secondary cancer tissues of women with high grade cervical intraepithelial dysplasia (CIN III). E. M. Hennig and...

Down Syndrome Link to Cancer Studied.(Brief Article)(Statistical Data Included)
February 1, 2000... 2000 FEB 1 - (NewsRx.com) -- While people with Down syndrome have a high chance of developing childhood leukemia, a new study shows they have only half the normal lifetime risk of getting other kinds of cancer. Experts already knew...

HBV Involved in non-B, non-C Chronic Liver Ailments.(Brief Article)(Statistical Data Included)
February 1, 2000... 2000 FEB 1 - (NewsRx.com) -- Hepatitis B virus infection may be involved in the pathogenesis of certain non-B, non-C chronic liver diseases. Although hepatitis B virus (HBV) DNA has been detected in the sera of patients with chronic...

Systemic Profile May Help in Cancer Diagnosis and Prognosis.(Brief Article)(Statistical Data Included)
February 1, 2000... 2000 FEB 1 - (NewsRx.com) -- A systemic angiogenic profile of cancer patients may be useful in monitoring anti-angiogenic therapy, according to researchers in Switzerland. Although in the normal healthy organism angiogenesis is a...

Glucose-Related Protein Is Related to Angiogenesis.(Brief Article)(Statistical Data Included)
February 1, 2000... 2000 FEB 1 - (NewsRx.com) -- Tumor vascularization and simultaneous expression of drug-resistance protein may be involved in therapeutic effectiveness. Several studies have documented that induction of the glucose-related protein...

Screening Proposed as a Substitute for Biopsies.(Brief Article)(Statistical Data Included)
February 1, 2000... 2000 FEB 1 - (NewsRx.com) -- Tamoxifen is well known as a treatment for breast cancer; however, it has also been linked to an increased risk of endometrial cancer. Indiana University investigators have suggested that women who take...

Vaginal Cytology and Histological Biopsy Critical for Diagnosis.(Brief Article)(Statistical Data Included)
February 1, 2000... 2000 FEB 1 - (NewsRx.com) -- Granulocytic sarcoma of the uterine cervix is often misdiagnosed in patients with acute myeloid leukemia (AML). This sarcoma, representing soft tissue masses of leukemic myeloblasts, is an unusual...

Environmental Exposure Increases Women's Cancer Risk.(Brief Article)(Statistical Data Included)
February 1, 2000... 2000 FEB 1 - (NewsRx.com) -- Women who live in China have some of the highest lung cancer rates in the world. Long-term exposure to home and occupational environmental tobacco smoke contributes significantly to this cancer rate, according...

Prophylactic Ovarian Surgery Depends on Several Factors.(Brief Article)(Statistical Data Included)
February 1, 2000... 2000 FEB 1 - (NewsRx.com) -- Some physicians will perform prophylactic oophorectomy (ovarian removal) at the time of a hysterectomy on postmenopausal women in order to prevent future ovarian cancer. Whether a patient receives this...

Association between PEG-3 and Angiogenesis Reported.(Brief Article)(Statistical Data Included)
February 1, 2000... 2000 FEB 1 - (NewsRx.com) -- by Cathy Clark, Senior Editor -- A nontransforming cancer progression gene may be an important target molecule for the inhibition of pathogenic angiogenesis. Subtraction hybridization identified a genetic...

CD44S Expression Correlates with Renal Clear Cell Carcinoma.(Brief Article)(Statistical Data Included)
February 1, 2000... 2000 FEB 1 - (NewsRx.com) -- CD44S expression correlates with disease progression in patients with renal clear cell carcinoma, researchers from the United States reported. "Recent reports have shown altered expression of CD44 in renal...

Equal Survival With Radical Prostatectomy and External Beam Radiation Therapy.(Brief Article)(Statistical Data Included)
February 1, 2000... 2000 FEB 1 - (NewsRx.com) -- Early stage prostate cancer patients with identical pretreatment prostate specific antigen (PSA) blood levels and Gleason scores (potential tumor aggressiveness determined by microscopic examination of the...

Mammography Not Recommended for Determining Origin of Metastatic Cancer.(Brief Article)(Statistical Data Included)
February 1, 2000... 2000 FEB 1 - (NewsRx.com) -- According to a recent study conducted by K. J. Stevens and colleagues, mammography does not prove to be of use in identifying occult primary breast cancer in women with spreading cancer of unknown origin ("Is...

Majority of Men Experience Impotence Following Radical Prostatectomy.(Brief Article)(Statistical Data Included)
February 1, 2000... 2000 FEB 1 - (NewsRx.com) -- A large-scale study of men who underwent radical prostatectomy for localized prostate cancer shows that at least 18 months following surgery, 59.9% were impotent and 8.4% were incontinent, according to an...

Researchers Discover High Risk Factors for Developing Stomach Cancer.(Brief Article)(Statistical Data Included)
February 1, 2000... 2000 FEB 1 - (NewsRx.com) -- Although an increased risk of stomach cancer has been associated with a family history of the disease and a common ulcer-causing bacterial infection, no previous study has examined the impact of the presence...

Lack of Lymphatic Vascular Specificity of VEGFR-3 Found.(Brief Article)(Statistical Data Included)
February 1, 2000... 2000 FEB 1 - (NewsRx.com) -- According to a study from the United States, there is a lack of lymphatic vascular specificity of vascular endothelial growth factor receptor 3 (VEGFR-3) in vascular tumors. "Among the molecules important...

Anticancer Strategy Redirects Natural Antibodies To New Target.(Brief Article)(Statistical Data Included)
February 1, 2000... 2000 FEB 1 - (NewsRx.com) A novel anticancer strategy redirects naturally occurring antibodies to a new target, researchers from the United States reported. "Antibodies against the disaccharide epitope galactosyl (alpha 1-3) galactose...

WT1 Is Target for Adoptive Immunotherapy of Leukemia.(Brief Article)(Statistical Data Included)
February 1, 2000... 2000 FEB 1 - (NewsRx.com) -- Researchers from the United Kingdom are exploring the use of WT1 transcription factor as a target for the isolation of cytotoxic T lymphocytes (CTL) for the adoptive immunotherapy of leukemia. ...

CD4(+) Cells Found Circulating in B-CLL Patients.(Brief Article)(Statistical Data Included)
February 1, 2000... 2000 FEB 1 - (NewsRx.com) -- Circulating CD4(+) cells were found in patients with B-chronic lymphocyte leukemia (B-CLL), reported researchers from the United Kingdom. B-CLL is characterized by the progressive accumulation of...

Immunotherapy Uses G250-scFV Transduced T Lymphocytes.(Brief Article)(Statistical Data Included)
February 1, 2000... 2000 FEB 1 - (NewsRx.com) -- Preclinical studies of immuno gene therapy of metastatic renal cell carcinoma (RCC) using the monoclonal antibody G250 were encouraging enough to prepare for a phase I/II clinical trial, researchers from The...

MHC Binding Peptides Used in Adoptive Anticancer Therapy.(Brief Article)(Statistical Data Included)
February 1, 2000... 2000 FEB 1 - (NewsRx.com) -- Major histocompatibility complex (MHC) binding peptides elicit cytotoxic and helper T-lymphocytes for the adoptive therapy of cancer, reported researchers from the United States. "Cytotoxic and helper T...

Assay Developed to Determine Fentanyl in Human Plasma.(Brief Article)(Statistical Data Included)
February 1, 2000... 2000 FEB 1 - (NewsRx.com) -- Researchers with Phoenix International Life Sciences, Quebec, Canada, have developed an assay using gas chromatography mass spectrometry for the determination of fentanyl, a synthetic opioid analgesic, in...

Tyrosine Kinase Receptor is a Potential Angiogenic Target.(Brief Article)(Statistical Data Included)
February 1, 2000... 2000 FEB 1 - (NewsRx.com) -- The tyrosine kinase receptor (TEK) is a potential angiogenic target for a cancer vaccine, suggested researchers from the United Kingdom. "Immune therapy of malignant tumors could be achieved by the...

Clinical Trial Shows Serum-Free Gene Transfer of Stem Cells.(Brief Article)(Statistical Data Included)
February 1, 2000... 2000 FEB 1 - (NewsRx.com) -- Researchers in Germany have reported on what may be the first clinical trial in chronic myelogenous leukemia achieving serum-free gene transfer into hematopoietic stem cells. Ex vivo culture can deplete...

Cell Lines Expressed Splice Variants of VEGF.(Brief Article)(Statistical Data Included)
February 1, 2000... 2000 FEB 1 - (NewsRx.com) -- All neuroblastoma cell lines examined in a recent study expressed the angiogenesis stimulator vascular endothelial growth factor (VEGF). Neuroblastoma is the most frequently occurring solid malignancy of...

Vaccine Technology Applied to a Second Cancer Indication.(Brief Article)(Statistical Data Included)
February 1, 2000... 2000 FEB 1 - (NewsRx.com) -- Avax Technologies, Inc, announced that its corporate Investigational New Drug (IND) Application for O-Vax, the company's proprietary haptenized autologous cell vaccine (AC Vaccine) for the treatment of...

Early Steps of Tumor Formation Documented in Animal Models.(Brief Article)(Statistical Data Included)
February 1, 2000... 2000 FEB 1 - (NewsRx.com) -- Researchers from Duke University Medical Center and Duke Comprehensive Cancer Center in Durham, North Carolina, have documented for the first time the earliest steps of the organization of cancer cells into...

Redirected Measles Virus Hemagglutinin Protein Attacks Cancer Cells.(Brief Article)(Statistical Data Included)
February 8, 2000... 2000 FEB 8 - (NewsRx.com) -- Redirection of measles virus hemagglutinin protein kills cancerous cells, reported researchers from the United States. "Measles virus (MV) induces a lethal cytopathic effect in infected cells, causing...

Defective Lkaros Gene Linked to Pediatric Leukemia.(Brief Article)(Statistical Data Included)
February 8, 2000... 2000 FEB 8 - (NewsRx.com) -- Molecular abnormalities in the lkaros gene may contribute to the development of acute lymphoblastic leukemia (ALL) in children, according to a study by Parker Hugher Cancer Center in Minnesota ("Expression of...

ISIS 5132 Specifically Reduces Target Gene Expression.(Brief Article)(Statistical Data Included)
February 8, 2000... 2000 FEB 8 - (NewsRx.com) -- Patients treated with the c-raf-1 antisense oligodeoxynucleotide ISIS 5132 (CGP 69846A) demonstrated c-raf-1 depletion and tumor responses, reported researchers from the United States. "Abnormally...

Molecular Genetics Aid Metastatic Disease Detection.(Brief Article)(Statistical Data Included)
February 8, 2000... 2000 FEB 8 - (NewsRx.com) -- Early metastatic disease may be detectable in blood specimens using molecular genetic methods, according to researchers from the United States. The use of molecular genetic methods for detection, role...

p21 Gene Transfer Induced Apoptosis in Esophageal Cancer Cells.(Brief Article)(Statistical Data Included)
February 8, 2000... 2000 FEB 8 - (NewsRx.com) -- Adenovirus-mediated p21(Sdi1) gene transfer induced differentiation-dependent apoptosis in human esophageal squamous cell carcinoma, determined a study from Japan. "When keratinocytes withdraw from the...

Peritoneal Mesothelial Cells Regulate Abdominal Diseases.(Brief Article)(Statistical Data Included)
February 8, 2000... 2000 FEB 8 - (NewsRx.com) -- Human peritoneal mesothelial cells are important regulators of various abdominal disease processes, according to researchers in Austria. Peritoneal mesothelial cells are uniquely located to regulate...

New Oral Fluoropyrimidines Are an Effective Treatment.(Brief Article)(Statistical Data Included)
February 8, 2000... 2000 FEB 8 - (NewsRx.com) -- According to a recent report published by R. J. Ignoffo at the University of California San Francisco, new oral fluoropyrimidines have been shown to be as effective against metastatic colorectal cancer as...

Tumors Primarily Detected at Beginning of Third Trimester; Teratomas are Most Common.(Brief Article)(Statistical Data Included)
February 8, 2000... 2000 FEB 8 - (NewsRx.com) -- Fetal brain tumors, rare neoplasms with mostly unknown cytogenics, are generally detected at the beginning of third trimester, and teratomas are the most common entity, according to research from Germany. ...

Unacceptable Toxicity Found in Intensified Treatment.(Brief Article)(Statistical Data Included)
February 8, 2000... 2000 FEB 8 - (NewsRx.com) -- A recent study involving an intense series of treatments for patients with advanced, previously untreated, resectable head and neck squamous cell carcinomas resulted in unacceptably high systemic toxicity,...

Radiofrequency Ablation Safe Treatment for Unresectable Tumors.(Brief Article)(Statistical Data Included)
February 8, 2000... 2000 FEB 8 - (NewsRx.com) -- Radiofrequency ablation can be used for patients with unresectable hepatic metastases, researchers say. A. J. Bilchik and colleagues tested radiofrequency ablation, a method for eliminating tumor cells by...

Stopping HCV is Best Way to Reduce Liver Cancers.(Brief Article)(Statistical Data Included)
February 8, 2000... 2000 FEB 8 - (NewsRx.com) -- Preventing hepatitis C virus infections is the most important factor in reducing the incidence of hepatocellular cancer, a study from Japan suggests. Researcher M. Mori and colleagues from the Saga Medical...

Relationship Between Outcome and M Stage Reported.(Brief Article)(Statistical Data Included)
February 8, 2000... 2000 FEB 8 - (NewsRx.com) -- Therapy, including postoperative chemotherapy and radiation, can cure some juvenile patients with medulloblastoma. M stage appears to have no bearing on survival rates, according to findings from a study...

Growth Factors to Reduce Platelet Requirements May Be Needed.(Brief Article)(Statistical Data Included)
February 8, 2000... 2000 FEB 8 - (NewsRx.com) -- Therapeutic results of dexamethasone, cytarabine, and cisplatin need to be improved by adding strategies to reduce myelotoxicity, according to researchers working in Canada. R. Haq and colleagues designed...

Accelerated Cisplatin Treatment Suggests Favorable Outcome.(Brief Article)(Statistical Data Included)
February 8, 2000... 2000 FEB 8 - (NewsRx.com) -- An accelerated weekly schedule (AWS) of cisplatin treatment has been associated with better long-term survival in advanced ovarian cancer patients as compared to the conventional 3-weekly schedule (CTWS),...

mIB-1 in Endometrial Carcinoma: Prognostic Significance.(Brief Article)(Statistical Data Included)
February 8, 2000... 2000 FEB 8 - (NewsRx.com) -- The monoclonal antibody MIB-1 is an independent prognostic indicator of 5-year survival, reported researchers from the United States. "mIB-1, a monoclonal antibody to the Ki-67 antigen, has presumptively...

Antiandrogen Therapy Immediately Following Radical Prostatectomy Improves Prognosis.(Brief Article)(Statistical Data Included)
February 8, 2000... 2000 FEB 8 - (NewsRx.com) -- A recent study completed by E. M. Messing and colleagues at the University of Rochester, New York, indicated that antiandrogen therapy immediately following radical prostatectomy and pelvic lymphadenectomy...

Molecular Studies Critical in Diagnosis.(Brief Article)(Statistical Data Included)
February 8, 2000... 2000 FEB 8 - (NewsRx.com) -- Molecular genetics studies need to be a routine part of diagnosis in solid tumors, according to researchers from the United States. Reverse-transcriptase polymerase chain reaction (RT-PCR) is a technique...

Cytosine Deaminase/5-Fluorocytosine-Based Vaccination Studied.(Brief Article)(Statistical Data Included)
February 8, 2000... 2000 FEB 8 - (NewsRx.com) -- Suicide gene-modified tumor cells may work as therapeutic vaccines against liver metastasis from colon carcinoma, suggested recent research from France. "The cytosine deaminase gene of Escherichia coli...

Angiogenesis Factors Involved in Neoplastic Growth.(Brief Article)(Statistical Data Included)
February 8, 2000... 2000 FEB 8 - (NewsRx.com) -- Angiopoietin-2, in the presence of vascular endothelial growth factor, may produce the initial angiogenic signal that accompanies tumor growth, according to a report from Italy. Experimental evidence has...

Laxatives and Smoking Contribute to Development of Renal Pelvis and Ureter Cancer.(Brief Article)(Statistical Data Included)
February 8, 2000... 2000 FEB 8 - (NewsRx.com) -- Habitual smoking and intake of laxatives pose a significant risk in the development of urothelial cancer (UC), particularly renal pelvis and ureter cancer, according to a recent report by W. Pommer and...

Targeting the HER-2/Neu Gene May Have Therapeutic Potential.(Brief Article)(Statistical Data Included)
February 8, 2000... 2000 FEB 8 - (NewsRx.com) -- Treatment strategies are being developed that target the molecular alteration of the HER-2/Neu gene in breast cancer patients, researchers from the United States reported. "The HER-2/Neu proto-oncogene...

B7.1 Gene Transfer Improves T-Cell Activation.(Brief Article)(Statistical Data Included)
February 8, 2000... 2000 FEB 8 - (NewsRx.com) -- B7.1 gene transfer protects T cells from apoptosis and improves their activation, researchers from Germany reported. "Expression of B7 on tumor cells can circumvent T-cell tolerance and lead to the...

CT Scans Used to Evaluated Lung Cancer Responses to Therapy.(Brief Article)(Statistical Data Included)
February 8, 2000... 2000 FEB 8 - (NewsRx.com) -- Chest CT scans of lung tumors undergoing gene therapy that progress will show an increase in size, researchers from the United States reported. "Adenoviral mediated transfer of wild type p53 into lung...

TIMP-2 Gene Transfer Prevents Liver Metastases.(Brief Article)(Statistical Data Included)
February 8, 2000... 2000 FEB 8 - (NewsRx.com) -- Adenoviral-mediated gene transfer of tissue inhibitor of metalloproteinases-2 (TIMP-2) into the liver prevents metastatic spread, reported researchers from Germany and the United Kingdom. "Metastatic...

Increase in Liver Cancer in Egypt due to Hepatitis C Virus.(Brief Article)(Statistical Data Included)
February 8, 2000... 2000 FEB 8 - (NewsRx.com) -- The trend in increasing incidence of hepatocellular carcinoma among patients with chronic liver disease in Egypt is due principally to the hepatitis C virus, researchers report. "Previous reports have...

Anti-Cancer Agents Work Via Anti-Angiogenic Mechanism.(Brief Article)(Statistical Data Included)
February 8, 2000... 2000 FEB 8 - (NewsRx.com) -- Adenoviral vectors encoding tumor suppressors show promise, according to a recent report. Sunil Chada and colleagues, Introgen Therapeutics, Inc. (Houston, TX, USA) developed adenoviral vectors encoding...

Olive Oil May Prevent Development of Bowel Cancer.(Brief Article)(Statistical Data Included)
February 8, 2000... 2000 FEB 8 - (NewsRx.com) -- Olive oil may protect against bowel cancer, research conducted in rats concludes. Previous research has shown that dietary fat helps to promote cancer but that the development of malignancy is associated...

Rb2 Therapy Shrinks Tumors in Mice.(Brief Article)(Statistical Data Included)
February 8, 2000... 2000 FEB 8 - (NewsRx.com) -- Researchers at Jefferson Medical College have for the first time used gene therapy to replace a damaged Rb2 gene with a healthy version and dramatically shrink lung cancer tumors in mice. The scientists,...

Company To Provide Start-Up Program for Oncology Patients.(Brief Article)(Statistical Data Included)
February 8, 2000... 2000 FEB 8 - (NewsRx.com) -- Coram Prescription Services (CPS), the Orlando, Florida-based specialty mail order pharmaceutical division of Coram Healthcare, announced that it has entered into an agreement with Roche Laboratories, Inc, to...

HPV Hotline Answers Questions.(Brief Article)(Statistical Data Included)
February 8, 2000... 2000 FEB 8 - (NewsRx.com) -- Public health officials at the American Social Health Association (ASHA) announced the launch of the first national human papillomavirus (HPV) hotline, one piece of their National HPV & Cervical Cancer...

Companies Extend Partnership, Continue Research of Telomerase Inhibitors.(Brief Article)(Statistical Data Included)
February 8, 2000... 2000 FEB 8 - (NewsRx.com) -- Geron Corporation announced that Pharmacia & Upjohn (PNU) has exercised an option to extend its drug-discovery collaboration with Geron. The companies established the initial partnership in March 1997....

Innovative Drug Delivery Shows Promise for Advanced Cancer.(Brief Article)(Statistical Data Included)
February 8, 2000... 2000 FEB 8 - (NewsRx.com) -- Atrix Laboratories, Inc. announced that it has achieved successful results in the ongoing Phase III human clinical trials for the treatment of prostate cancer. This innovative product uses the company's...

Women Who Experience Failure on Tamoxifen Have New Option.(Brief Article)(Statistical Data Included)
February 8, 2000... 2000 FEB 8 - (NewsRx.com) -- Pharmacia & Upjohn announced the US availability of Aromasin (exemestane tablets), the first oral aromatase inactivator for the treatment of postmenopausal women with advanced breast cancer whose tumors stop...

Cancer Summit Leads to First Global Network Unifying Research in Fight Against Cancer.(Brief Article)(Statistical Data Included)
February 15, 2000... 2000 FEB 15 - (NewsRx.com) -- The Charter of Paris Against Cancer was signed on February 4, 2000, by more than 100 international leaders in government, patient advocacy, cancer research, and global corporations at the first World Summit...

Eukaryotic Initiation Factor May Have Prognostic Role.(Brief Article)(Statistical Data Included)
February 15, 2000... 2000 FEB 15 - (NewsRx.com) -- Eukaryotic initiation factor-4E may have a role as a prognostic factor in bladder cancer, according to researchers in England. J. P. Crew and colleagues performed a study to investigate mechanisms...

High Microvessel Count Is Most Important Prognostic Factor.(Brief Article)(Statistical Data Included)
February 15, 2000... 2000 FEB 15 - (NewsRx.com) -- A high microvessel count at the deepest invasive portion of colorectal cancer is the most important prognosis predictor, according to a research team working in Japan. Hiroshima University School of...

Researchers Uncover Mitochondrial Defect Involved with Inherited Cancers.(Brief Article)(Statistical Data Included)
February 15, 2000... 2000 FEB 15 - (NewsRx.com) -- Researchers from the University of Pittsburgh in Pennsylvania have uncovered a concept of how a certain type of tumor develops by linking a specific defect in mitochondria to a type of inherited tumor. ...

Cancer Patients May Need Pre-Operative Nutritional Support.(Brief Article)(Statistical Data Included)
February 15, 2000... 2000 FEB 15 - (NewsRx.com) -- According to a study from Japan, cancer patients with insulin resistance may need pre-operative nutritional support. Researchers have found that insulin resistance in these patients has a significant...

Extent, Size of Tumor Are Primary Survival Indicators.(Brief Article)(Statistical Data Included)
February 15, 2000... 2000 FEB 15 - (NewsRx.com) -- A recent study shows that the extent and size of lung cancer (LC) tumors are the most reliable prognostic indicators of long-term survival. Age, histology and stage of disease were also found to...

"Lymphochip" Genetically Distinguishes Lymphomas.(Brief Article)(Statistical Data Included)
February 15, 2000... 2000 FEB 15 - (NewsRx.com) -- By arraying nearly 18,000 genes on a glass chip about twice the size of a postage stamp and recording the expression patterns of those genes, researchers have obtained detailed molecular portraits of a form...

Wire Localization Is Effective for Resection.(Brief Article)(Statistical Data Included)
February 15, 2000... 2000 FEB 15 - (NewsRx.com) -- A recent study shows that non-palpable metastatic melanoma may be resected via computed tomography (CT) or ultrasound-guided wire localization. The technique provides numerous benefits, the study found,...

Study: Dying Kids Suffer Needlessly.(Brief Article)(Statistical Data Included)
February 15, 2000... 2000 FEB 15 - (NewsRx.com) -- Childhood cancer was an almost certain death sentence 30 years ago, with 9 of every 10 victims succumbing to the disease. The death rate has dropped to 1 in 4, but researchers say many of those who die suffer...

Complementary Health Practices Much More Widespread than Is Suspected by Doctors.(Brief Article)(Statistical Data Included)
February 15, 2000... 2000 FEB 15 - (NewsRx.com) -- A study published in the February 1, 2000, issue of Cancer reveals that 37% of prostate cancer patients undergoing treatment with conventional therapy also turn to one or more complementary health practices....

Beta Carotene Supplementation Does Not Prevent Nonmelanoma Skin Cancer.(Brief Article)(Statistical Data Included)
February 15, 2000... 2000 FEB 15 - (NewsRx.com) -- Twelve years of beta carotene supplementation does not appear to affect the development of a first nonmelanoma skin cancer, including basal cell and squamous cell carcinomas, according to an article appearing...

Four Endovascular Delivery Routes Compared.(Brief Article)(Statistical Data Included)
February 15, 2000... 2000 FEB 15 - (NewsRx.com) -- Targeted endovascular delivery may be a good way to deliver antitumor therapies. Anti-angiogenic therapies are developing as a major new way to inhibit tumor growth. Target sites and delivery routes for...

Suicide Gene Therapy Uses Ifosfamide and 5-Fluorocytosine Prodrugs.(Brief Article)(Statistical Data Included)
February 15, 2000... 2000 FEB 15 - (NewsRx.com) -- Combination chemotherapy by the local activation of the prodrugs ifosfamide and 5-fluorocytosine was a successful gene therapy strategy in a murine model of breast cancer, researchers from Germany and Austria...

Transforming Growth Factor-(beta) Antisense Used in Murine Model.(Brief Article)(Statistical Data Included)
February 15, 2000... 2000 FEB 15 - (NewsRx.com) -- Gene therapies using transforming growth factor-(beta) (TGF-(beta)) may be effective approaches in the treatment of bladder cancer, researchers from Taiwan reported. The possibility of inhibiting gene...

Survival Rates Significantly Worse for African American Women.(Brief Article)(Statistical Data Included)
February 15, 2000... 2000 FEB 15 - (NewsRx.com) -- Research presented February 6, 2000, at the Society of Gynecologic Oncologists annual meeting found that survival rates of African Americans with advanced stage endometrial cancers are significantly worse...