Cancer Weekly articles from December 2004

Cancer Weekly archives from December 2004

Topoisomerase II alpha is a prognostic indicator in breast cancer.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Topoisomerase II alpha is a prognostic indicator in breast cancer, pathologists at Tel Aviv University report. "Topoisomerase II-alpha (Topo II-alpha) is a nuclear enzyme. Its expression rises...

Study: Shorter, more aggressive treatments better control disease.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Women receiving care at small, local radiation therapy facilities are less likely to receive shorter, more aggressive treatments for their cervical cancer, according to a study by M.D. Anderson Cancer...

Genetic markers of tumorogenic aberrant crypt foci identified.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Genetic markers of tumorogenic aberrant crypt foci (ACF) have been identified in a murine marker of colon cancer. In a recent study from the United States, conducted to "determine whether cancer...

Dendritic cell-tumor fusion vaccines being developed for renal cell carcinoma.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Dendritic cell-tumor fusion vaccines are being developed for renal cell carcinoma. "Renal cell carcinoma is a malignant disease that demonstrates resistance to standard chemotherapeutic agents. A...

Allogeneic stem-cell transplantation for renal-cell cancer reviewed.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Researchers review allogeneic stem-cell transplantation for renal-cell cancer in a recent issue of Lancet Oncology. "Metastatic renal-cell carcinoma (RCC) is resistant to chemotherapy, and patients...

Corrections being made to Louisiana abortion brochure.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Less than a week after learning that a state brochure incorrectly said abortions could increase the risk of breast cancer, health officials had a new version up on the Internet. It will take a bit...

Oral etoposide has a cytoreductive effect in relapsed ALL.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Oral etoposide has a cytoreductive effect in relapsed acute lymphoblastic leukemia. According to a study from the United States, "We evaluated the clinical response to low-dose etoposide in relapsed...

L-ascorbic acid represses NF-kappa B/COX-2 expression in acute myeloid leukemia.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- L-ascorbic acid represses NF-kappa B/COX-2 expression in acute myeloid leukemia. "There is increasing evidence that L-ascorbic acid (LAA) is selectively toxic to some types of cancer cells at...

Nuclear localization of adenovirus E4orf4 protein correlates with cell death.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Nuclear localization of adenovirus E4orf4 protein correlates with cell death. "The adenovirus E4orf4 protein induces p53-independent death of human cancer cells by a mechanism requiring interactions...

Scientists successful in "death clock" gene hunt.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Medical scientists at the University of Leicester have narrowed the search for the "death clock" gene in humans. Their study relates to a hunt for a gene that has important implications for aging...

Intracellular SAH removal may be therapeutic option in alcoholic liver disease.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Intracellular S-adenosylhomocysteine removal may be a therapeutic option in alcoholic liver disease. According to a study from the United States, "In alcoholic liver disease, tumor necrosis...

Study: FG-2216 increases endogenous EPO production in humans.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- FibroGen, Inc., announced that oral administration of FG-2216, the company's investigational therapy for anemia, was safe and well-tolerated and significantly increased production of endogenous...

GAD 67KD antisense leaves colon cancer cells susceptible to cancer therapy.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- GAD 67KD antisense leaves colon cancer cells susceptible to cancer therapy. According to a study from South Korea, "in eukaryotes, glutamate decarboxylase (GAD) expression was found in brain,...

Intratumoral CCL5 overexpression delays tumor growth.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Intratumoral CCL5 overexpression delays tumor growth. According to recent research from France, "Chemokines participate in the antitumor immune response by regulating the movement and positioning...

NF-kappa B activation by API2/MALT1 fusions inhibits p53 dependant apoptosis.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- NF-kappa B activation by API2/MALT1 fusions inhibits p53 dependant apoptosis. According to published research from the United States, "Interactions between survival pathways and apoptotic cascades...

High incidence of autoimmune hemolytic anemia complicating SCT in children.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- There is a high incidence of autoimmune hemolytic anemia complicating stem cell transplantation in pediatric patients. "Hemolytic anemia is a recognized complication of hematopoietic cell...

Cancer reference laboratory named to Deloitte's Fast 500 list.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- US LABS announced that it has ranked 181 on the 2004 Deloitte Technology Fast 500, a ranking of the 500 fastest-growing technology companies in North America. The company also ranked sixth on the...

Scott Hawley named American Cancer Society research professor, awarded $300,000.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Scott Hawley, PhD, investigator at the Stowers Institute for Medical Research, has been named an American Cancer Society (The Society) Research Professor. The designation carries an award of $300,000...

Plasma elements deem VEGF a biomarker for intestinal cancer transformation.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Plasma elements deem VEGF a biomarker for intestinal cancer transformation. "Vascular endothelial growth factor (VEGF) is known to play a key role in tumor angiogenesis. Our preliminary published...

Type-1 innate and acquired immunity play crucial roles in tumor immunotherapy.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Type-1 innate and acquired immunity play crucial roles in tumor immunotherapy. According to a study from Japan, "the discovery of a large array of tumor antigens has demonstrated that host...

Promising data presented on phase 2 trial drug for superficial bladder cancer.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Spectrum Pharmaceuticals, Inc. (SPPI) announced encouraging efficacy and safety data from the ongoing multi-center phase 2 trial of EOquin as a single agent in patients with recurrent superficial...

Novel technique isolates/tracks rare lymphoid stem cell that facilitates BMT.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- A novel technique was developed that isolates and tracks a rare lymphoid stem cell that facilitates bone marrow transplantation. "Bone marrow cells are composed of pluripotent stem cells to...

Trisacryl gelatin microspheres effective for preoperative embolization.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Trisacryl gelatin microspheres are highly effective for embolization of bone neoplasms prior to surgical removal. Radiologists in Austria conducted a study "to compare the efficacy of trisacryl...

Post-therapy damage in medulloblastoma patients can be mistaken for new tumors.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Irradiation and high-dose chemotherapy used to treat two types of brain tumors - medulloblastoma and supratentorial PNET - can cause changes in the brain's white matter that look like tumors when seen...

"Knowledge management" system could "revolutionize" treatment.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Scientists in the U.K. have designed a knowledge management system that they think could enable medical practitioners to make speedy, informed decisions about breast cancer patients. The project...

GATA3 mutations identified in breast tumors.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- A number of breast tumor GATA3 mutations have been identified and characterized. "GATA3 is an essential transcription factor that was first identified as a regulator of immune cell function,"...

Accelerated partial breast irradiation new option for breast cancer patients.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Women diagnosed with breast cancer must weigh the options between old tried- and-true and next-generation breast cancer treatments An estimated 216,000 American women will be diagnosed with breast...

Apoptotic response of tamoxifen-resistant breast tumor cells clarified.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Expression of apoptosis-related genes has been characterized in tamoxifen (TAM)-resistant breast tumor cells. In a recent study, oncologists in Germany "examined alterations in the apoptotic...

Breast cancer study examines new radiofrequency ablation assisted lumpectomy.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- The University of Arkansas for Medical Sciences (UAMS), and RITA Medical Systems, Inc., (RITA) announced that the first patient in a planned series of 30 received a radiofrequency ablation-assisted...

Chemotherapies have varied effects on menopausal symptoms of cancer patients.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Oncologists in Belgium have studied "the changes in frequency and severity of menopausal symptoms in patients receiving tamoxifen or aromatase inhibitors and identified factors influencing these...

Data on radiation dose from digital mammography reported from large study.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Radiologists in Spain have reported the mean and range of radiation dose from digital mammography calculated from data on over 5,000 patients. M. Chevalier, of the University of Complutense Madrid,...

Elizabeth Edwards's diagnosis encourages others to get check-ups.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Elizabeth Edwards said she is glad her breast cancer diagnosis is encouraging people to stop neglecting their own health, as she admits she did. "I didn't test myself as often," and didn't get...

Endogenous BRCA1-IRIS may influence DNA replication initiation machinery.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Endogenous BRCA1-IRIS may positively influence the DNA replication initiation machinery. According to published research from the United States, "Breast cancer is the most common malignancy among...

Enhancing cancerous area on MR mammography compared with pathological exam.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- According to a study from Belgium, "The enhancing area surrounding breast carcinoma on magnetic resonance (MR) mammography is correlated with findings from pathological examination. "We studied 194...

Genes linked to breast tumor progression and/or metastasis identified.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- A number of novel breast tumor genes linked to progressive disease and/or metastasis have been identified. "Breast carcinoma is a complex disease characterized by accumulation of multiple genetic...

HER2-positive disease invades organs due to fatal chemical attraction.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Researchers at The University of Texas M.D. Anderson Cancer Center have solved the mystery of why an aggressive form of HER2-positive breast cancer travels readily to a few key organs - lungs, liver,...

Hierarchical clustering of breast tumor immunomarkers has high prognostic value.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Hierarchical clustering analysis of breast tumor immunohistochemical data has high prognostic value. "Prognostically relevant cluster groups, based on gene expression profiles, have been recently...

In BRCA1/2 mutation carriers, cancer may mimic benign lesions on mammogram.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- A study involving BRCA 1/2 gene mutation carriers found that a significant number of circumscribed non-calcified mammographic masses found in these patients were malignant. "Breast cancers in gene...

New surgical technique determines if cancer has spread.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Women in Britain with breast cancer will soon benefit from a pioneering surgical technique developed in Wales. Robert Mansel and his team at Cardiff University, Wales College of Medicine, recently...

Obesity, lymph node status, and prognosis in breast cancer explored.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Researchers have investigated the associations of obesity, lymph node status, and prognosis in breast cancer patients. According to recent research from Norway, "Breast cancer patients who are...

Patients receiving taxane-based chemotherapy not at higher risk of pneumonitis.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Researchers at The University of Texas M.D. Anderson Cancer Center have shown that breast cancer patients treated with taxane-based chemotherapies and radiation are not at increased risk of developing...

Phage display library from lymph nodes of breast cancer patients constructed.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Researchers have constructed phage display libraries from reactive lymph nodes of breast carcinoma patients. According to a study from Germany, "The display of recombinant antibody fragments on the...

Plasma prolactin levels associated with increased postmenopausal disease risk.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Study findings suggest that plasma prolactin levels are associated with increased postmenopausal risk of breast cancer. "Prolactin is important in human breast development, and substantial...

Private practice in Munich, Germany, selects mammography system.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- A new private practice in Munich, Germany, has chosen Sectra's revolutionary digital mammography system, Sectra MicroDose Mammography. The new practice will focus on the low-dose concept and will...

Saudi Arabia: National guidelines on breast cancer management needed.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Data revealing variability and/or deficiencies in breast cancer management among surgeons and hospitals in Saudi Arabia have at least one group of surgeons there calling for national guidelines to set...

Trial evaluates supplemental screening sonography in dense breasts.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- A clinical trial is evaluating use of supplemental screening sonography to detect cancer in dense breasts. "In single-center trials across 42,838 examinations, 150 (0.35%) cancers were identified...

Women willing to deal with negative aspects of screening to gain benefit.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- There is nothing pleasant about getting a mammogram done, but overall, women are willing to put up with the discomfort and potential anxiety for the benefit of early detection of breast cancer. ...

Biopharma reports third quarter 2004 results, clinical achievements.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Progenics Pharmaceuticals, Inc., (NASDAQ: PGNX) announced its results of operations for the third quarter ended September 30, 2004, and for the first 9 months of 2004. Revenues for the third...

Biopharmaceuticals company announces third quarter results, progress made.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Keryx Biopharmaceuticals announced its financial results for the third quarter ended Sept. 30, 2004. At Sept. 30, 2004, Keryx announced cash, cash equivalents, interest receivable and investment...

Biotech company announces restructured agreement for cancer drug.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Ligand Pharmaceuticals announced that it has restructured its agreement with Eli Lilly and Company with respect to the royalties payable to Lilly on sales of Ligand's marketed cancer drug Ontak...

Dermatology pharmaceutical company announces financing, new hires.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Neosil Incorporated announced that it closed a $32 million placement of series A Preferred Stock to a group of investors led by MPM Capital and Burrill & Company. The financing will enable Neosil...

Developer of surgical and diagnostic products announces financial results.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Neoprobe Corporation (OTCBB:NEOP) announced consolidated operating results for the third quarter of 2004. Third quarter results included revenues of $1.7 million, representing increases of 46%...

Pharmaceutical firm reports loss of $0.18 per share.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Ariad Pharmaceuticals, Inc., (ARIA) announced consolidated financial results for the quarter ended September 30, 2004, and provided an overview of the clinical development of AP23573. "In the third...

Biotech establishes new business units for pain and oncology.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Ligand Pharmaceuticals announced that it has established separate therapeutically focused business units for its pain and oncology products. Patrick M. Shea, formerly vice president of marketing,...

ComfortScan agreements inked in Canada, Italy, and Russia.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- DOBI Medical International, Inc., (DBMI) announced that it signed distribution agreements for the ComfortScan system with several leading medical suppliers including Horizon Medical Services, Ltd., in...

IUN and Theragenics Corporation sign 3-year strategic alliance agreement.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- International Physician Networks dba International Urology Network (IUN) has entered into a 3-year exclusive, strategic alliance agreement with Theragenics Corporation (TGX). This agreement will...

Molecular diagnostics company announces expansion of diagnostic pipeline.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Third Wave Technologies Inc. (TWTI) provided new details about the expansion of the company's molecular diagnostic pipeline and issued preliminary guidance for 2005 clinical molecular diagnostic...

New company to develop, produce patient-specific cancer vaccines.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Baylor Health Care System announced its formation of a cancer immunotherapy company, known as ODC Therapy, Inc. ODC will develop, produce and distribute customized cancer vaccines, including a...

BRCA1 missense variant thwarts transcriptional activity.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- One of two BRCA1 missense variants identified by researchers in the U.S. has deleterious effects on gene transcription. "Many families with multiple cases of ovarian cancer, breast cancer, or both...

Clinical studies needed to evaluate role of BRCA1 in chemotherapy response.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Prospective clinical studies are needed to evaluate the role of BRCA1 in response to taxane-based chemotherapy, researchers say. Loss of BRCA1 function is associated with sensitivity to...

SOCS1 and 2 genes suppress growth of ovarian and breast carcinoma cells.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Suppressor of cytokine signaling genes 1 and 2 suppress the growth of ovarian and breast carcinoma cells, researchers in Australia have shown. "Suppressor of cytokine signaling (SOCS) proteins have...

Fused cell vaccination and CpG oligodeoxynucleotides reject tumor recurrence.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Fused cell vaccination and CpG oligodeoxynucleotides reject tumor recurrence. "Immunization with dendritic cells (DCs) using various antigen (Ag)-loading approaches has shown promising results in...

Standardized reviews of glioblastoma vascular patterns assist treatment choice.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Standardized reviews of glioblastoma vascular patterns assist treatment choice. "In a recent study, the existence of distinct vascular patterns with prognostic impact has been described in...

Vascular targeting agent, radiation reduces tumor growth by 98% in animals study.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Peregrine Pharmaceuticals, Inc. (PPHM) announced that Philip Thorpe, PhD, a member of its scientific advisory board, gave the keynote presentation at the Vascular Targeting Agents conference in...

Hepatitis C infection encourages liver cancer recurrence after resection.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Hepatitis C infection encourages liver cancer recurrence after resection. "Hepatocellular carcinoma (HCC) is closely associated with chronic hepatitis B or C virus (HBV, HCV) infection. Tumor...

OC Auto Micro 80 analyzer detects blood in stool samples.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Polymedco, Inc., has announced the addition of a new analyzer to their existing offering of automated testing platforms. The OC Auto Micro 80 analyzer processes a new, FDA-cleared immunochemical test to...

Program to implement required Pap interpretation proficiency testing announced.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Women will soon begin to have added assurance that the medical professionals who read their Pap tests are qualified to do so. The "added assurance" will be provided by a nationwide proficiency test...

p21Waf1 gene transfer via gene gun technology limits esophageal cancer growth.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- p21Waf1 gene transfer via gene gun technology limits esophageal cancer growth. According to published research from Japan, "in our previous study, the proliferation rate of esophageal squamous cell...

European cancer organization offers guidelines for treating anemia.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- New European Organization for Research and Treatment of Cancer (EORTC) guidelines aim to assist physicians in managing anemia more effectively in their patients with cancer by providing advice on the...

Radiation therapy systems selected to supply Wave 7 of UK Cancer Plan.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Varian Medical Systems, Inc. (VAR), U.K. developer of radiation therapy systems, will be supplying 7 new linear accelerators to 4 U.K. radiotherapy centers in the newest wave of the Department of...

Skin cancer study using MedPulser Electroporation Therapy system begins.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Genetronics Biomedical Corp. (GEB), a late-stage developer of oncology and other therapies using electroporation, has begun treating skin cancers in patients with primary and recurrent solid tumors...

VELCADE gets fast track status for relapsed and refractory mantle cell lymphoma.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Millennium Pharmaceuticals, Inc., (MLNM) announced that the U.S. Food and Drug Administration (FDA) has granted VELCADE fast track designation for relapsed and refractory mantle cell lymphoma, an...

Listeria-based cancer vaccines segregate immunogenicity from toxicity.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Listeria-based cancer vaccines segregate immunogenicity from toxicity. According to a study from the United States, "The facultative intracellular bacterium Listeria monocytogenes is being developed...

Dendritic cells boost antitumor activity of adoptively transferred T cells.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Dendritic cells strongly boost the antitumor activity of adoptively transferred T cells in vivo. According to published research from the United States, "Dendritic cells (DCs) have been well...

Expression of the cell surface mucin gene family in adenocarcinomas reported.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Scientists report the expression of the cell surface mucin gene family in adenocarcinomas in a recent issue of the International Journal of Oncology. According to recent research from Australia,...

IL-13 antagonist and Pseudomonas toxin fusion protein is anticancer.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- An interleukin-13 receptor-targeted cytotoxin composed of IL-13 antagonist and Pseudomonas exotoxin exhibited antitumor activity. According to a study from the United States, "We have shown...

Tumor vaccine therapy reviewed.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Researchers review tumor vaccine therapy in a recent issue of Blood. According to published research from the United States, "Fusion proteins containing chemokine receptor ligands have been used to...

Interleukin-15 transfection plus CD8+ T cells cause colon cancer rejection.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Interleukin-15 transfection plus CD8+ T cells cause colon cancer rejection. "Although interleukin (IL)-15 augments innate and acquired immunities, IL-15 expression is controlled at the levels of...

Biopharma company's cell cycle inhibitor work published in Science.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Cyclacel Group plc, a U.K.-based biopharmaceutical company, announced that the editor of Science magazine cited a chemistry paper by Cyclacel scientists regarding its CYC103 targeted drug discovery...

New evidence found for cancer stem cells.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- In the past, evidence from leukemia has helped to support the theory that cancer stem cells maintain the disease in patients. But until now researchers struggled to find proof of these stem cells in...

Chemoradiation with gemcitabine an alternative for patients with renal failure.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Chemoradiation with gemcitabine is an alternative for patients with renal failure when cisplatin-based therapy is contraindicated, study results indicate. L. Cetina and colleagues, National...

Clinical trial investigates food supplement's preventive effects.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Did your grandmother always tell you to eat your greens? It appears that she may have known something scientists are only now discovering. When the substances produced in cruciferous vegetables...

HPV 16 infection a risk factor for disease progression in younger women.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Infection with human papillomavirus 16 infection is a significant risk factor for cervical cancer progression in younger women, study data indicate. "Human papillomaviruses (HPV), particularly type...

Small cell neuroendocrine carcinomas of the uterine cervix characterized.
December 7, 2004... 2004 DEC 7 - (NewsRx.com & NewsRx.net) -- Pathologists with Yamagata University, Japan, recently characterized small cell neuroendocrine carcinomas of the uterine cervix. G.M. Ishida and colleagues stated, "Small cell carcinomas of the...