Cancer Weekly articles from December 2000

Cancer Weekly archives from December 2000

New Susceptibility Gene - ATR - Identified.
December 5, 2000... 2000 DEC 5 - (NewsRx.com & NewsRx.net) -- A report published in the December 1, 2000, issue of the journal Genes & Development provides the first evidence that ATR may be the newest breast cancer susceptibility gene. Mutations in the...

Abnormal Gene Silencing May Lead to Disease Progression.
December 5, 2000... 2000 DEC 5 - (NewsRx.com & NewsRx.net) -- Scientists at Emory University, Atlanta, Georgia, have discovered that a mistake in the way DNA is labeled and packaged could lead to the abnormal silencing of a gene that plays an important role in...

Scientists Give Golgi Apparatus its Own Identity.
December 5, 2000... 2000 DEC 5 - (NewsRx.com & NewsRx.net) -- Researchers at Yale University have discovered that, contrary to previous beliefs, the Golgi apparatus is an organelle that exists independently of the larger endoplasmic reticulum and is a crucial...

Amifostine Effective for Prevention of Radiotherapy Side Effects.
December 5, 2000... 2000 DEC 5 - (NewsRx.com & NewsRx.net) -- Oncologists at Duke University report that amifostine can effectively prevent some adverse effects commonly experienced by head and neck cancer patients after radiation therapy. "Radiotherapy for...

Cell Studies May Further Gene Therapy Prospects.
December 5, 2000... 2000 DEC 5 - (NewsRx.com & NewsRx.net) -- New laboratory research at the University of North Carolina may lead to ways of treating head and neck cancer with gene therapy. The study, published November 20, 2000, in the journal Human Gene...

Hemoglobin Levels Can Help Predict Chemoradiation Therapy Outcome.
December 5, 2000... 2000 DEC 5 - (NewsRx.com & NewsRx.net) -- Hemoglobin levels prior to chemoradiation therapy for advanced head and neck cancer provide an accurate prognostic marker of outcome, suggesting a possible adjunct therapy, researchers in Germany...

Raman Spectroscopy Useful in Diagnosis.
December 5, 2000... 2000 DEC 5 - (NewsRx.com & NewsRx.net) -- Researchers report in the journal Laryngoscope that Raman spectroscopy is a useful diagnostic tool for patients with possible cancer of the larynx. "Raman spectroscopy, the analysis of scattered...

Activity Reported for Genasense in Cancer Combination Therapy.
December 5, 2000... 2000 DEC 5 - (NewsRx.com & NewsRx.net) -- Genta Inc. (GNTA), Berkeley, Heights, New Jersey, announced that investigators have reported early positive results from a clinical trial of Genasense, an antisense compound for the treatment of...

European Commission Grants "Orphan" Status for Treatment.
December 5, 2000... 2000 DEC 5 - (NewsRx.com & NewsRx.net) -- Wyeth-Ayerst Laboratories, Madison, New Jersey, announced that the European Commission has designated Mylotarg (gemtuzmab ozogamicin) as an "orphan medicinal product." The Commission decision...

Trial of Local Chemotherapy for Metastatic Disease Opens for Enrollment.
December 5, 2000... 2000 DEC 5 - (NewsRx.com & NewsRx.net) -- The University of Iowa is one of seven centers participating in a clinical trial testing a new treatment for metastatic brain tumors and invites affected people to participate in the study. ...

Oxaliplatin Study Will Be Evaluated in Stage II/III Patients.
December 5, 2000... 2000 DEC 5 - (NewsRx.com & NewsRx.net) -- Iowa University (IU) of Iowa Health Care is participating in Protocol C-07, a newly launched colorectal cancer trial. The study will test the benefits of oxaliplatin in combination with the current...

New Technology Spares Healthy Tissue.
December 5, 2000... 2000 DEC 5 - (NewsRx.com & NewsRx.net) -- Fox Chase Cancer Center, Philadelphia, Pennsylvania, has acquired a new technology that allows a more precise delivery of high-dose radiation to tumors while sparing healthy tissues and critical...

Halofuginone Diminishes New Blood Vessel Growth by Squelching Key Steps.
December 5, 2000... 2000 DEC 5 - (NewsRx.com & NewsRx.net) -- Halofuginone has gained interest as a potentially powerful agent in the fight against cancer. It has been proposed for use against a variety of cancer types. New research evidence indicates that...

Variety of Cancers and Metabolic Disorders Respond to Thalidomide.
December 5, 2000... 2000 DEC 5 - (NewsRx.com & NewsRx.net) -- Teams of researchers from the Arkansas Cancer Research Center, Cedars-Sinai Medical Center, M.D. Anderson Cancer Center, Texas, and the U.S. National Cancer Institute presented updated clinical trial...

Agent Demonstrates Tumor Suppression Activity.
December 5, 2000... 2000 DEC 5 - (NewsRx.com & NewsRx.net) -- Introgen Therapeutics Inc. (INGN), Austin, Texas, reported preclinical data on its INGN 241, Adenoviral-mda-7 drug candidate. The data were published in The Journal of Gene Medicine and presented...

Strategies Target Type 1 Insulin-Like Growth Factor Receptor.
December 5, 2000... 2000 DEC 5 - (NewsRx.com & NewsRx.net) -- McGill University researchers have developed several gene therapeutic approaches to combatting cancer metastases. The strategies target the type 1 insulin-like growth factor receptor (IGF-1R),...

Heat Shock Protein-Peptide Complex Shown Safe and Immunogenic in Humans.
December 5, 2000... 2000 DEC 5 - (NewsRx.com & NewsRx.net) -- Results of a pilot study of a heat shock protein-peptide vaccine in patients with advanced cancer show the preparation is safe and produces an effective immune response. One of the benefits of heat...

Progress with Targeted, Anticancer, Virus-Based Therapeutics Reported.
December 5, 2000... 2000 DEC 5 - (NewsRx.com & NewsRx.net) -- Onyx Pharmaceuticals, Inc. (ONXX) announced that clinical and preclinical data demonstrating the breadth of the company's promising approaches to treating cancer were presented at the 11th Annual...

Blood Flow in Uterine Cancers May Predict Progression and Metastasis.
December 5, 2000... 2000 DEC 5 - (NewsRx.com & NewsRx.net) -- Blood flow rates and vascular endothelial growth factor correspond with increased angiogenesis in endometrial cancers, and might potentially be used as a good prediction factor for tumor progression and...

Excess Estrogen May Increase Risk.
December 5, 2000... 2000 DEC 5 - (NewsRx.com & NewsRx.net) -- Prolonged elevation in estrogen levels can put women with endometriosis at increased risk of cancer, researchers at the Mayo Clinic in Rochester, Minnesota, suggest. "Endometriosis is extremely...

Genetic Biomarker Could Improve Diagnosis and Treatment.
December 5, 2000... 2000 DEC 5 - (NewsRx.com & NewsRx.net) -- Researchers at the University of Maryland School of Medicine and the University of Southern California have discovered a genetic biomarker that may help doctors to better diagnose and treat cancer of...

Epidermal Growth Factor Receptor Increases VEGF in Presence of Hypoxia.
December 5, 2000... 2000 DEC 5 - (NewsRx.com & NewsRx.net) -- Glioblastoma cells express more vascular endothelial growth factor (VEGF) in the presence of epidermal growth factor receptor (EGFR) activation and hypoxia, it was reported at the 42(nd) Annual Meeting...

Reovirus Therapy Successful in Animal Models.
December 5, 2000... 2000 DEC 5 - (NewsRx.com & NewsRx.net) -- Dr. Peter Forsyth and his research group at the Tom Baker Cancer Centre in Calgary, Alberta, Canada, presented the results of their work with Reolysin (Oncolytics) for the treatment of malignant...

Phase II MG98 Trial Commences.
December 5, 2000... 2000 DEC 5 - (NewsRx.com & NewsRx.net) -- MGI Pharma, Inc. (MOGN), Minneapolis, Minnesota, and MethylGene Inc., Montreal, Quebec, Canada, have initiated a Phase II trial in Canada and the United States with MG98 in recurrent or metastatic...

Antisense Drug Reported Active in Malignant Disease.
December 5, 2000... 2000 DEC 5 - (NewsRx.com & NewsRx.net) -- Genta Incorporated (GNTA) announced that researchers reported that Genasense(TM), the company's lead antisense compound, reduced levels of Bcl-2 protein, caused major antitumor responses, and possibly...

M-Vax Reported to Prolong Survival in Resected Stage IV Patients.
December 5, 2000... 2000 DEC 5 - (NewsRx.com & NewsRx.net) -- Avax Technologies, Inc. (AVXT), Kansas City, Missouri, announced that data relating to M-Vax, its proprietary autologous cell vaccine for melanoma, were presented at the 18th Chemotherapy Foundation...

Diagnostic Radioactive Compound Also May be Therapeutic.
December 19, 2000... 2000 DEC 19 - (NewsRx.com & NewsRx.net) -- A surprising, promising new weapon against a common childhood cancer, neuroblastoma, is the radioactive compound normally used for imaging the tumor. A radioactive compound used for the past two...

Oral Bacteria Can Increase Carcinogenic Effect of Alcohol.
December 19, 2000... 2000 DEC 19 - (NewsRx.com & NewsRx.net) -- A bacterium that makes its home in the human oral cavity can magnify the carcinogenic effects of alcohol consumption, oncologists in Japan report. "Many epidemiological studies have identified...

Postmenopausal Use of Hormones Does Not Increase Risk.
December 19, 2000... 2000 DEC 19 - (NewsRx.com & NewsRx.net) -- Postmenopausal use of exogenous female hormones does not significantly increase the risk for developing breast carcinoma in women with proliferative benign breast lesions beyond the level of risk...

Preliminary Results Demonstrate Feasibility of RITA System for Tumor Ablation.
December 19, 2000... 2000 DEC 19 - (NewsRx.com & NewsRx.net) -- Preliminary results from a clinical feasibility study suggest that the RITA system can be used to safely ablate breast tumors. This feasibility study involved the ablation of small malignant...

Safeguard Devised for Potentially Powerful, but Dangerous Drug.
December 19, 2000... 2000 DEC 19 - (NewsRx.com & NewsRx.net) -- Researchers who had been advancing a promising cancer treatment - Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand, or TRAIL - found a new obstacle looming in 1999 when the journal Nature...

TP73 May Be a Tumor-Suppressor Gene.
December 19, 2000... 2000 DEC 19 - (NewsRx.com & NewsRx.net) -- The tumor suppressor protein p53 is one of the best characterized proteins in the cell, in part, because the gene encoding it (TP53) is mutated in nearly 50% of all human tumors. For years, p53 was...

Radiation Therapy Does Not Adversely Effect Function.
December 19, 2000... 2000 DEC 19 - (NewsRx.com & NewsRx.net) -- Mayo Clinic researchers report that facial nerve grafts do not exhibit any functional deficiencies after high doses of therapeutic radiation. "Some authors believe radiotherapy is so detrimental to...

Microsatellite Analysis Can Predict Recurrence.
December 19, 2000... 2000 DEC 19 - (NewsRx.com & NewsRx.net) -- Mutations in short genome sequences called microsatellites may hold information about the risk of local recurrence for patients with cancer of the head and neck. "We examined the possibility of...

Tracheal Autotransplantation Can Repair Postoperative Defects.
December 19, 2000... 2000 DEC 19 - (NewsRx.com & NewsRx.net) -- Surgeons can use part of the trachea to preserve larynx function in patients who undergo partial laryngectomy for advanced laryngeal or sinus cancer, researchers report. P.R. Delaere and...

Epstein-Barr Virus Serology Has Practical Diagnostic Use.
December 19, 2000... 2000 DEC 19 - (NewsRx.com & NewsRx.net) -- Using the presence of Epstein-Barr virus antigens in the blood to test for nasopharyngeal cancer provides an acceptable degree of accuracy, and a significant improvement in cost-effectiveness, compared...

Interim Statistical Analysis Announced of Phase II URSO Study.
December 19, 2000... 2000 DEC 19 - (NewsRx.com & NewsRx.net) -- Axcan Pharma Inc. (Axcan), Mont-Saint-Hilaire, announced interim statistical analysis results of its Phase II study assessing the efficacy of the use of URSO for the prevention of the recurrence of...

Conference Focuses on Complementary Medicine in Cancer.
December 19, 2000... 2000 DEC 19 - (NewsRx.com & NewsRx.net) -- Many patients use them, but just where do complementary and alternative medicines fit into care for people with cancer? A conference held November 18, 2000, attempted to help answer that question...

Breakthrough Announced in Treatment of Solid Tumors.
December 19, 2000... 2000 DEC 19 - (NewsRx.com & NewsRx.net) -- BioPulse International, Inc. (BIOP), San Ysidro, California, announced what it believes is a major breakthrough in the treatment of solid tumors using a new mixture of anti-cancer cytokines. ...

Breast Imaging Reporting Module Has Undergone Extensive In-Practice Testing.
December 19, 2000... 2000 DEC 19 - (NewsRx.com & NewsRx.net) -- TalkStation Breast Imaging Reporting Module is a BIRADs compliant speech-enabled reporting system designed to synchronize with radiologist's workflow and simplify the interpretation of breast imaging...

Partnership Combines Drug Delivery Systems.
December 19, 2000... 2000 DEC 19 - (NewsRx.com & NewsRx.net) -- FeRx Inc., announced November 28, 2000, a partnership with Elan Corporation, plc, to develop, manufacture, and commercialize FeRx's lead product, MTC-DOX, currently in Phase I/II clinical trials in the...

Positive Phase II Response Rate Data on RSR13 Announced.
December 19, 2000... 2000 DEC 19 - (NewsRx.com & NewsRx.net) -- Allos Therapeutics, Inc. (ALTH), Denver, Colorado, announced positive preliminary response rate data for treatment of patients with locally advanced, inoperable non-small cell lung cancer (NSCLC). ...

Virulizin Effective in Pre-Clinical Tests.
December 19, 2000... 2000 DEC 19 - (NewsRx.com & NewsRx.net) -- Pre-clinical data show that pancreatic tumors that are resistant to gemcitabine treatment respond to virulizin therapy. Lorus Therapeutics Inc. (LOR; LORFF) announced November 27, 2000, that its...

Pre-Clinical Research Demonstrates Tumor-Killing Technology.
December 19, 2000... 2000 DEC 19 - (NewsRx.com & NewsRx.net) -- Photogen Technologies Inc. (PHGN), Knoxville, Tennessee, announced that senior scientist Craig Dees, PhD, discussed pre-clinical research demonstrating how the company's potential cancer therapeutic, a...

Growth Factor Expression in Macrophages More Frequent in Avascular Tumor Sites.
December 19, 2000... 2000 DEC 19 - (NewsRx.com & NewsRx.net) -- Although vascular endothelial growth factor (VEGF) expression is a major factor in the neovascularization of cancerous tumors, in breast cancer tumors, macrophages that express VEGF are more often...

Enhanced Immune Response Improves Immunization Efficiency.
December 19, 2000... 2000 DEC 19 - (NewsRx.com & NewsRx.net) -- Researchers at Dendreon Corporation have reported a novel method for generating an enhanced immune response with potentially important implications for improving the efficiency of therapeutic cancer...

HIF-1 May be New Drug Target.
December 19, 2000... 2000 DEC 19 - (NewsRx.com & NewsRx.net) -- Harvard Medical School researchers have identified a polypeptide that slows tumor growth by interfering with gene regulation. All treatments for cancer are based on the concept of exploiting the...

Hepatitis B Virus Reactivation Rate is High in Patients Receiving Cancer Treatment.
December 19, 2000... 2000 DEC 19 - (NewsRx.com & NewsRx.net) -- - by Sonia Bell-Nichols, staff medical writer -- The risk for hepatitis B virus (HBV) reactivation is high in patients who undergo cytotoxic chemotherapy for cancer, scientists in Hong Kong say. ...

VEGF is a Marker for Bronchogenic Cancers.
December 19, 2000... 2000 DEC 19 - (NewsRx.com & NewsRx.net) -- Vascular endothelial growth factor (VEGF) continues to be expressed by bronchogenic cancer cells that are implanted into nude mice, researchers recently reported at Chest 2000, sponsored by the...

Epstein-Barr Virus Gene May be Involved in Development of Malignancy.
December 19, 2000... 2000 DEC 19 - (NewsRx.com & NewsRx.net) -- Expression of the Epstein-Barr virus (EBV) BARF1 gene may be partly responsible for the transformation of healthy nasopharyngeal epithelial cells into carcinomas, oncologists report. "We reported...

Global Partnerships for Health, Biotech Content Announced.
December 19, 2000... 2000 DEC 19 - (NewsRx.com & NewsRx.net) -- NewsRx.com(TM), Atlanta, Georgia, recently announced partnerships with several international firms, including EBSCO Online, Factiva, and the new iSyndicate Europe-Bertelsmann venture. "iSyndicate...

Study in Primary Treatment of Cancer Commences.
December 19, 2000... 2000 DEC 19 - (NewsRx.com & NewsRx.net) -- BICO, Inc. (BIKO), Pittsburgh, Pennsylvania, and a subsidiary of ViaCirQ, Inc., announced that it has commenced a study with Wake Forest University Baptist Medical Center utilizing the ThermoChem-HT...

Clinical Trial Shows Irofulven Holds Promise.
December 19, 2000... 2000 DEC 19 - (NewsRx.com & NewsRx.net) -- Results from a Phase II clinical trial of irofulven, a novel anti-cancer agent being developed by MGI Pharma, Inc. (MOGN), demonstrated anti-tumor activity in patients with advanced pancreatic cancer...

Study Suggests Targeting Signaling Pathway to Limit Tumor Progression.
December 19, 2000... 2000 DEC 19 - (NewsRx.com & NewsRx.net) -- The results of experiments performed by Johns Hopkins University School of Medicine researchers suggest that by blocking special signaling pathways linked to cancer cell growth, prostate cancer...

Young Patients with Cancer and Hepatitis C Fare as Well as Adults.
December 19, 2000... 2000 DEC 19 - (NewsRx.com & NewsRx.net) -- A pilot study of young cancer patients with chronic hepatitis C who were treated with combination interferon/ribavirin therapy has shown that it is as effective in children as in adults. Children...

Researchers Create Compound Believed to Fight Cancerous Tumors.
December 26, 2000... 2000 DEC 26 - (NewsRx.com & NewsRx.net) -- Biochemistry researchers at the University of Texas Southwestern Medical Center at Dallas have created a synthetic cancer-fighting compound found naturally in some marine sponges that scientists around...

Diffusion MRI Gives Early Signs of Cancer's Response to Treatment.
December 26, 2000... 2000 DEC 26 - (NewsRx.com & NewsRx.net) -- Cancer patients who now endure months of treatment - and then weeks of anxious waiting to see if it worked - may soon get word of their tumors' response within days of starting therapy, thanks to a new...

Potent Platinum-Based Drug Shows Promise in Clinical Trials.
December 26, 2000... 2000 DEC 26 - (NewsRx.com & NewsRx.net) -- Clinical trials of a new platinum-based cancer drug could hold promise for many cancer patients, in particular the nearly 25,000 women in the United States who develop ovarian cancer each year,...

Animal Model Shows Vitamin D-3 Analog Could be Preventive in Humans.
December 26, 2000... 2000 DEC 26 - (NewsRx.com & NewsRx.net) -- Scientists have been able to arrest the growth of colonic adenocarcinomas in rats using a vitamin D-3 analog. They say that this same compound could potentially be used for preventing colon cancers in...

Smoking is a Risk Factor.
December 26, 2000... 2000 DEC 26 - (NewsRx.com & NewsRx.net) -- An American Cancer Society study links 12% of colorectal cancer deaths to cigarette smoking. In the largest prospective study of cigarette smoking and colorectal cancer mortality, American Cancer...

Treatment Strategies Demonstrate Arsenic Trioxide Might Prove Useful.
December 26, 2000... 2000 DEC 26 - (NewsRx.com & NewsRx.net) -- Clinical experts presented data on four separate clinical trials demonstrating that long-lasting, high rates of complete remission can be achieved with arsenic trioxide therapy for acute promyelocytic...

Trial Results Using Thalidomide are Encouraging.
December 26, 2000... 2000 DEC 26 - (NewsRx.com & NewsRx.net) -- Researchers from the Arkansas Cancer Research Center; Mayo Clinic, Minnesota, and the M.D. Anderson Cancer Center, Texas, presented data at the 42nd annual meeting of the American Society of Hematology...

Soybean-Based Chemical May Help Prevent Disease.
December 26, 2000... 2000 DEC 26 - (NewsRx.com & NewsRx.net) -- A chemical derived from soybeans has been found to shrink abnormal growths that lead to oral cancer, a University of California, Irvine (UCI), College of Medicine clinical study has found. The...

Cysteine-Rich Proteins Regulate Cancer Cell Growth.
December 26, 2000... 2000 DEC 26 - (NewsRx.com & NewsRx.net) -- Prostate cells grown in the lab are regulated by newly recognized cysteine-rich proteins called "insulin-like growth factor-binding protein-related proteins" (IGFBP-rPs), new research indicates. ...

Foundation Calls for Increased Research.
December 26, 2000... 2000 DEC 26 - (NewsRx.com & NewsRx.net) -- The Brain Tumor Progress Review group (BTPRG) recently recommended that the U.S. National Cancer Institute (NCI) adopt a "concerted, interdisciplinary, and timely approach" to brain tumor research. ...

FDA Approves Application for Phase II Ablation Treatment.
December 26, 2000... 2000 DEC 26 - (NewsRx.com & NewsRx.net) -- Celsion Corp. (CLN), Columbia, Maryland, announced that the U.S. Food and Drug Administration (FDA) has approved its application to proceed with Phase II clinical studies of its investigational breast...

First Patient Treated with MRI-Guided HIFU System.
December 26, 2000... 2000 DEC 26 - (NewsRx.com & NewsRx.net) -- EDAP TMS S.A. (EDAPY) announced December 13, 2000, that its magnetic resonance imaging (MRI)-guided high intensity focused ultrasound (HIFU) system has been successfully used for the first time in...

Phase II Study in Postmenopausal Women Shows Promising Results for Aromasin.
December 26, 2000... 2000 DEC 26 - (NewsRx.com & NewsRx.net) -- Updated results from a randomized Phase II study in the first-line treatment of advanced breast cancer in postmenopausal women taking Aromasin (exemestane tablets) show that it may demonstrate a high...

Novel Approach to Controlling the Spread of Certain Types of Cancers Identified.
December 26, 2000... 2000 DEC 26 - (NewsRx.com & NewsRx.net) -- Synaptic Pharmaceutical Corporation (SNAP) announced it has discovered a new, naturally-occurring, peptide ligand that may play a role in controlling the spread of cancer cells. The peptide ligand...

Anti-Angiogenic and Anti-Chemotactic Agents May be Best Defenses.
December 26, 2000... 2000 DEC 26 - (NewsRx.com & NewsRx.net) -- A new study suggests that the best way to fight adrenocortical cancer is to use therapies that target angiogenic and chemotactic activities in those tumors. "Adrenocortical carcinoma is a highly...

Levulan PDT Successfully Used to Treat Dysplastic Disorder.
December 26, 2000... 2000 DEC 26 - (NewsRx.com & NewsRx.net) -- DUSA Pharmaceuticals, Inc. (DUSA) reported that independent investigators at the University of Sheffield, United Kingdom, have published the results of the first randomized clinical study using...

Chemotherapy + Herceptin Improves Response Rate in Patients with Advanced Disease.
December 26, 2000... 2000 DEC 26 - (NewsRx.com & NewsRx.net) -- The addition of weekly Taxol (paclitaxel) plus Paraplatin (carboplatin) to Herceptin (trastuzamab) improves patient response and disease control in metastatic, or advanced, breast cancer that...

Risk Related to Insulin-Resistance, Elevated Levels of Sex Hormones.
December 26, 2000... 2000 DEC 26 - (NewsRx.com & NewsRx.net) -- University of Buffalo researchers have confirmed a significant link between breast cancer risk and physical characteristics of insulin resistance and higher-than-normal male and female sex hormones in...

Data Support Development of Gene-Based Immunotherapies.
December 26, 2000... 2000 DEC 26 - (NewsRx.com & NewsRx.net) -- Vical Inc. (VICL), San Diego, California, presented data supporting conclusions that excellent safety profiles and encouraging efficacy results warrant continued development of the company's gene-based...

Gene-Based Anti-Angiogenesis Therapy Preclinical Results Presented.
December 26, 2000... 2000 DEC 26 - (NewsRx.com & NewsRx.net) -- Introgen Therapeutics, Inc. (INGN), San Diego, California, reported preclinical results for its gene-based anti-angiogenesis therapy, INGN 241, an adenoviral-mda7 product candidate, currently in Phase...

Herbal Medicine Eases Interferon's Weight Loss Effects.
December 26, 2000... 2000 DEC 26 - (NewsRx.com & NewsRx.net) -- Oriental herbal medicine combined with interferon-alpha A/D eases body weight loss in treatment of metastatic renal cell carcinoma. Juzen-taiho-to, a Japanese and Chinese traditional herbal...

Human Leukemic T Cells Effective Treatment for Brain Tumors.
December 26, 2000... 2000 DEC 26 - (NewsRx.com & NewsRx.net) -- The human leukemic T-cell line, TALL-104, kills human malignant brain tumor cells, researchers report. C.A. Kruse, of the University of Colorado, and associates conducted pre-clinical studies of...

Common Mode of Action Likely in Gene-Activation Molecules Linked to Cancers.
December 26, 2000... 2000 DEC 26 - (NewsRx.com & NewsRx.net) -- In a just-completed study, two collaborating groups of scientists at The Wistar Institute have identified the structure of a molecule known to regulate gene expression. The molecule, called Esa1,...

Cancer-Fighting Eggs in the Works.
December 26, 2000... 2000 DEC 26 - (NewsRx.com & NewsRx.net) -- The creators of Dolly the Sheep announced on December 7, 2000, plans to mass-produce cancer-fighting drugs in the eggs of genetically modified chickens. The Roslin Institute in Edinburgh, Scotland,...

Hypoxia and Growth Factor Combine to Influence Angiogenesis in Human Tumor Cells.
December 26, 2000... 2000 DEC 26 - (NewsRx.com & NewsRx.net) -- Hypoxia has an additive influence on epidermal growth factor receptor (EGFR) activation of vascular endothelial growth factor (VEGF) expression in glioblastoma cells, researchers say. A study of...

Automated Cell Imaging System Detects Overexpression of Breast Cancer Protein.
December 26, 2000... 2000 DEC 26 - (NewsRx.com & NewsRx.net) -- At the 23rd annual San Antonio Breast Cancer Symposium, held in San Antonio, Texas, during December 2000, medical researchers reported results of a study showing automated cell imaging adapted from...

New Vaccine to be Tested.
December 26, 2000... 2000 DEC 26 - (NewsRx.com & NewsRx.net) -- Cancer researchers are testing a new vaccine that they hope will use the body's immune system to attack cancer cells. The trial is for patients who have a form of skin cancer called melanoma in...

Two Studies Show Decitabine a Potential Broad-Spectrum Platform Therapy.
December 26, 2000... 2000 DEC 26 - (NewsRx.com & NewsRx.net) -- SuperGen (SUPG, SUPGZ) announced that the results of two clinical studies of its proprietary anticancer compound, decitabine, were recently presented at the 42nd Annual Meeting of the American Society...

Cooperative Development of Tumor Vaccine Considered.
December 26, 2000... 2000 DEC 26 - (NewsRx.com & NewsRx.net) -- Biovest International, Englewood Cliffs, New Jersey, announced that it has entered negotiations with the U.S. National Cancer Institute (NCI) for a Cooperative Research and Development Agreement...