Cancer Weekly articles from August 2000

Cancer Weekly archives from August 2000

Epidermal Growth Factor Receptor Variant Promotes Tumor Formation.
August 1, 2000... 2000 AUG 1 - (NewsRx.com) -- Important new evidence linking epidermal growth factor receptor vIII with tumorigenesis has been reported by Georgetown University medical researchers in the journal Cancer Research. According to these...

p53 Gene Transfer Inhibits Anaplastic Large Cell Lymphoma in vivo.
August 1, 2000... 2000 AUG 1 - (NewsRx.com) -- Adenovirus-mediated gene transfer of p53 may be useful for gene therapy of lymphomas. "Adenovirus-p53-mediated apoptosis has been extensively evaluated in animal xenografts derived from human epithelial...

Study Finds Colonoscopy May be Best Way to Screen.
August 1, 2000... 2000 AUG 1 - (NewsRx.com) -- In the July 20, 2000, issue of the New England Journal of Medicine, researchers from the U.S. Department of Veterans Affairs (VA), Portland, Oregon, report on the largest study ever done on screening the...

Report Urges Closer Look at Cardiotoxicity of Breast Cancer Drug Trastuzumab (Herceptin).
August 1, 2000... 2000 AUG 1 - (NewsRx.com) -- Although trastuzumab (Herceptin) has been lauded as being beneficial in the treatment of breast cancer, its use is associated with a high incidence of cardiac toxicity and raises important questions about...

Variability in Cancer Registration in U.K. May Distort Statistics.
August 1, 2000... 2000 AUG 1 - (NewsRx.com) -- Variations in the way breast cancer is registered in U.K. hospitals is leading to missed cases and, as a result, may be distorting national cancer statistics - currently a principal means of identifying cancer...

p53 Gene Transfer Inhibits p53-Mutated Human Melanoma Cells.
August 1, 2000... 2000 AUG 1 - (NewsRx.com) -- Wild-type p53 gene transfer inhibits p53-mutated melanoma in vitro, researchers in Italy report. "The tumor suppressor gene p53 has inhibitory effects on cell growth and angiogenesis and induces apoptosis...

Patients More Likely Than Physicians to Detect Disease.
August 1, 2000... 2000 AUG 1 - (NewsRx.com) -- A prospective evaluation of 471 patients newly diagnosed with cutaneous melanoma found that the majority (57%) detected their own melanoma, reports a study published in the July 15, 2000, issue of Cancer. ...

Nitrite/Nitrate Test a Good Tumor Marker.
August 1, 2000... 2000 AUG 1 - (NewsRx.com) -- Over the past several years, scientists have been using several serum or plasma markers to indicate chronic liver diseases. Two of these include alpha-fetoprotein (AFP) and alanine aminotransferase (ALT). ...

Combined Criteria Predict Response to Hepatic Arterial Infusion Chemotherapy.
August 1, 2000... 2000 AUG 1 - (NewsRx.com) -- A study published in the July 15, 2000, issue of Cancer reports that the application of combined criteria of thymidylate synthase (TS) quantitation and in vitro chemosensitivity demonstrates the predicted...

Radiation Increases Growth Factor Expression in Chemotherapy Patients.
August 1, 2000... 2000 AUG 1 - (NewsRx.com) -- More analysis of the influence of chemotherapy on vascular endothelial growth factor expression (VEGF) in lung cancer patients was reported recently in the Journal of Cancer Research and Clinical Oncology. ...

p53, PCNA, and Ki-67 Evaluated as Prognostic Indicators.
August 1, 2000... 2000 AUG 1 - (NewsRx.com) -- A study conducted in Turkey evaluated the prognostic value of p53, proliferating cell nuclear antigen (PCNA), and Ki-67 expression in 35 patients with undifferentiated nasopharyngeal carcinomas. E. Genc...

Low-Dose Oral Contraceptives are as Protective as Older, High-Dose Pills.
August 1, 2000... 2000 AUG 1 - (NewsRx.com) -- Low-dose contraceptives currently on the market are just as effective as the older, high-dose preparations in protecting women from ovarian cancer, according to a study published in the August 1, 2000, issue...

Cancer Cell Growth Appears Related to Evolution of Plump Fruits and Vegetables.
August 1, 2000... 2000 AUG 1 - (NewsRx.com) -- The genetic mechanism that through millennia of evolution has created plump and juicy fruits and vegetables could also be involved in the proliferation of human cancer cells. Plant biologists and computer...

Refined and Whole Grains Linked to Oral, Esophageal, and Laryngeal Cancers?
August 1, 2000... 2000 AUG 1 - (NewsRx.com) -- Researchers in Switzerland have investigated the possible links between refined grains and whole grains and an increased risk of oral, esophageal, and laryngeal cancers. The University Hospital of...

Rare Early Onset in HIV Patient Treated Effectively with Daunoxome.
August 1, 2000... 2000 AUG 1 - (NewsRx.com) -- Daunoxome (liposomal daunorubicin) proved a safe and effective alternative to polychemotherapy in an HIV patient with early onset Kaposi's sarcoma (KS). "Since the introduction of highly active...

Advances May Improve Cancer Treatment.
August 1, 2000... 2000 AUG 1 - (NewsRx.com) -- Radiation therapy, the treatment of disease with penetrating beams of particles such as X-rays, has long been a primary weapon in the war on cancer. That's because X-rays and other forms of radiation can...

Some Renal Grafts are Tumorous at Donation.
August 1, 2000... 2000 AUG 1 - (NewsRx.com) -- Kidney allografts should be examined prior to transplantation for the presence of renal cell carcinoma (RCC), researchers from Germany recommend. "Numerous studies have reported an increasing prevalence of...

New Laser Treatment May Replace Lumpectomy.
August 1, 2000... 2000 AUG 1 - (NewsRx.com) -- A new procedure being tested at Rush-Presbyterian-St. Luke's Medical Center in Chicago, Illinois, holds much promise for eliminating the need for surgery in women with small breast cancers. This procedure...

Phase I Testing for a Ras Pathway Inhibitor Initiated.
August 1, 2000... 2000 AUG 1 - (NewsRx.com) -- Onyx Pharmaceuticals, Inc. announced that the company, along with its partner Bayer Corporation, initiated Phase I clinical testing in Germany for a Ras pathway inhibitor as a cancer therapy. A U.S....

Phase II Studies Initiation for Anti-Cancer Compound Announced.
August 1, 2000... 2000 AUG 1 - (NewsRx.com) -- Tularik Inc., San Francisco, California, announced the initiation of Phase II efficacy and Phase I combination studies in major cancer centers worldwide for its anti-cancer compound T64 (lometrexol). T64...

Individualized Stage III Melanoma Vaccine Commercialized.
August 1, 2000... 2000 AUG 1 - (NewsRx.com) -- Avax Technologies, Inc., Kansas City, Missouri, announced that its autologous cancer vaccine (AC Vaccine) for melanoma, M-Vax, is now commercially available in Australia, for administration to individuals with...

Licensing Agreement Entered in Area of Cancer Diagnostics.
August 1, 2000... 2000 AUG 1 - (NewsRx.com) -- Millennium Predictive Medicine, Inc. (MPMx), Cambridge, Massachusetts, announced they have entered into a licensing agreement with Becton Dickinson and Company (BD), Franklin Lakes, New Jersey, in the area of...

American Mayapple Yields Anti-Cancer Extract.
August 1, 2000... 2000 AUG 1 - (NewsRx.com) -- A common plant called mayapple may offer an alternative to an Asian plant that's been harvested almost to extinction for an anti-cancer extract, U.S. Agricultural Research Service administrator Floyd Horn...

DNA Probes Introduced to Detect IGH/BCL2 and Other IGH Gene Rearrangements.
August 1, 2000... 2000 AUG 1 - (NewsRx.com) -- Vysis, Inc. (VYSI), Downers Grove, Illinois, announced at the 13th International Symposium on Treatment of Leukemia and Cancer, held in New York, New York, during July 2000, that it has expanded its line of DNA...

Phase III Trial of Bcl-2 Antisense Plus Chemotherapy Begins.
August 1, 2000... 2000 AUG 1 - (NewsRx.com) -- US Oncology (USON), Houston, Texas, announced the opening of a randomized Phase III trial of Bcl-2 antisense (G3139; Genta, Inc., Lexington, Massachusetts) in combination with standard chemotherapy for...

Orphan Drug Designation Received for Arsenic Trioxide.
August 1, 2000... 2000 AUG 1 - (NewsRx.com) -- Arsenic TriOxide (ATO), a cancer drug treatment by Cell Therapeutics, Inc. (CTI), Seattle, Washington, has been granted orphan drug designation for the treatment of myelodysplastic syndromes (MDS) by the U.S....

Twin Study Emphasizes Role of Diet, Lifestyle on Cancer Risk.
August 1, 2000... 2000 AUG 1 - (NewsRx.com) -- In light of an important study appearing in the July 13, 2000, issue of the New England Journal of Medicine, researchers associated with the American Institute for Cancer Research (AICR) reminded the public...

Prophylactic Immunization May Actually Stimulate Tumor Growth.
August 8, 2000... 2000 AUG 8 - (NewsRx.com) -- Researchers in the United States reported startling results from experiments with prophylactic cancer vaccines. "One major objective of tumor immunologists is to prevent cancer development in individuals...

New Tool Identifies Patients in Whom Cancer Has Spread.
August 8, 2000... 2000 AUG 8 - (NewsRx.com) -- A new diagnostic tool, now being used in patients with melanoma or breast cancer to determine if a cancer has spread, is also highly accurate in women with squamous cancer of the vulva, report researchers from...

Oral Antisense Oligonucleotide Targets Protein Kinase A and Cooperates with Taxol.
August 8, 2000... 2000 AUG 8 - (NewsRx.com) -- An orally-delivered antisense oligonucleotide helped inhibit tumor growth, angiogenesis, and growth factor production in a murine model. "Protein kinase A type I (PKAI) transduces mitogenic signals from...

Study Maps Formation Process of Estrogen Receptor-Negative Cancer Cells.
August 8, 2000... 2000 AUG 8 - (NewsRx.com) -- A slow-motion movie of the changes inside a breast cell as it becomes a particularly stubborn type of cancer cell would show a process very much like that depicted for the first time in a new study by...

Procedures for Determining Lymph Node Involvement.
August 8, 2000... 2000 AUG 8 - (NewsRx.com) -- Imaging technology is more accurate than palpation and ultrasound in diagnosing squamous cell carcinoma of the larynx, researchers report. "Squamous cell carcinoma is the most common malignant neoplasm of...

Vascular Endothelial Growth Factor Marks Response to Therapy for Gastric Cancer.
August 8, 2000... 2000 AUG 8 - (NewsRx.com) -- New research conducted at the Osaka College of Medicine in Japan shows that vascular endothelial growth factor (VEGF) expression in gastric carcinoma patients treated with 5-fluorouracil (5-FU) and cisplatin...

Cost of Care for Enrolled Patients is Same as for Standard Treatment.
August 8, 2000... 2000 AUG 8 - (NewsRx.com) -- There is new evidence that the costs associated with participating in a clinical trial are not greater than receiving standard cancer care, according to researchers reporting in the August 2000 issue of the...

Comorbidity Affects Survival Outcome.
August 8, 2000... 2000 AUG 8 - (NewsRx.com) -- Researchers in Canada have found that comorbidity can be a significant factor in the overall survival of patients with head and neck cancer. In North America, patients with head and neck cancer due to...

Estimated Growth Rate Plays Role in Determining Treatment Strategy.
August 8, 2000... 2000 AUG 8 - (NewsRx.com) -- Researchers in The Netherlands suggest that estimating the doubling time of paragangliomas can help physicians determine course of treatment for patients. "Extraadrenal paragangliomas of the head and neck...

Erythropoietin Raises Hemoglobin Levels Prior to Surgery.
August 8, 2000... 2000 AUG 8 - (NewsRx.com) -- Researchers in Canada have found that preoperative erythropoietin can raise the hemoglobin levels of patients prior to head and neck oncologic surgery. R.M. Gall and colleagues from the University of...

Checkpoint Gene Monitors Cell Division; Cancer Clinical Applications Seen.
August 8, 2000... 2000 AUG 8 - (NewsRx.com) -- In health, most cells undergo a carefully orchestrated cell-division process in order to replicate. At the heart of this process is mitosis, in which a cell's nucleus duplicates its genetic material and...

Difficulty in Swallowing Common After Radiotherapy.
August 8, 2000... 2000 AUG 8 - (NewsRx.com) -- Researchers in the People's Republic of China have found that patients commonly experience dysphagia after treatment by radiotherapy for nasopharyngeal carcinoma. Fifty patients were included in a study by...

Treatments Improve Outcome for Patients with Malignant Germ Cell Tumors.
August 8, 2000... 2000 AUG 8 - (NewsRx.com) -- Conservative surgery is the treatment of choice in young patients with malignant ovarian germ cell tumors (MOGCT) confined to a single ovary, according to a study featured in the July 15, 2000, issue of...

Metastasis-Related Gene Expression a Better Predictor for Advanced Cancer.
August 8, 2000... 2000 AUG 8 - (NewsRx.com) -- University of Texas medical investigators say that genetic expression of markers for metastasis can more reliably differentiate organ-confined and advanced prostate cancer. In fact, these markers are more...

Three Areas on Chromosomes Contain Aggressive Genes.
August 8, 2000... 2000 AUG 8 - (NewsRx.com) -- Little is currently known about what makes some prostate cancer biologically aggressive and more likely to progress to metastatic and potentially lethal disease. One compelling possibility is that genetic...

Researchers Crack Rosetta Stone for Tumor Suppressor Protein in Worms.
August 8, 2000... 2000 AUG 8 - (NewsRx.com) -- Uncovering the structure of a "Rosetta Stone" protein may help scientists understand how cells are programmed to die, and in turn, the role loss of the process plays in cancer. Researchers, lead by Charles...

Lipiodol/Adenovirus Gene Therapy Vector Interactions Evaluated in vivo.
August 8, 2000... 2000 AUG 8 - (NewsRx.com) -- Researchers in Japan have evaluated the interactions between Lipiodol and adenovirus vector for gene delivery to hepatocellular carcinoma (HCC) cells both in vitro and in vivo. "In gene therapy for cancer,...

Researchers Create New Algorithm for Early Detection.
August 8, 2000... 2000 AUG 8 - (NewsRx.com) -- A new technique for detecting prostate cancer using a computerized algorithm has shown promising results and will be investigated further in a multi-site U.S. study. The prospective study of 151 men,...

Study Will Evaluate Potential Impact of Angiogenesis Inhibitors Over Next Decade.
August 8, 2000... 2000 AUG 8 - (NewsRx.com) -- Investigation of the therapeutic value of angiogenesis inhibitors is one of the most dynamic, highly visible, and entrepreneurial areas of cancer research, and many cancer care facilities are poised to...

Progress of Ongoing Phase III Xcytrin Trial Reported.
August 8, 2000... 2000 AUG 8 - (NewsRx.com) -- Pharmacyclics, Inc. (PCYC), Sunnyvale, California, reported on the progress of its on-going randomized controlled Phase III clinical trial of Xcytrin (motexafin gadolinium) Injection for the treatment of cancer...

Phase I Clinical Trial of Anticancer Platform TAPET Initiated.
August 8, 2000... 2000 AUG 8 - (NewsRx.com) -- Vion Pharmaceuticals, Inc. (VION), New Haven, Connecticut, announced the initiation of a Phase I human clinical trial of its TAPET bacterial vector (Tumor Amplified Protein Expression Therapy) at The Royal...

Additional Phase III Clinical Study Initiated in Patients Undergoing Radiation Therapy.
August 8, 2000... 2000 AUG 8 - (NewsRx.com) -- IntraBiotics Pharmaceuticals, Inc. (IBPI), Mountain View, California, said it has begun patient enrollment for the second of two Phase III clinical trials related to one of its lead product candidates,...

FDA Approves Implantable Drug Pump for Use in Treatment.
August 8, 2000... 2000 AUG 8 - (NewsRx.com) -- An implantable drug pump from Medtronic, Inc. (MDT), Minneapolis, Minnesota, received approval from the U.S. Food and Drug Administration (FDA) for use in a colorectal liver cancer treatment that delivers...

State Encourages Fecal Occult Blood Test as First Line of Defense.
August 8, 2000... 2000 AUG 8 - (NewsRx.com) -- People age 50 and older in Wright County, Minnesota, can receive a free fecal occult blood test (FOBT) annually for three years through the "Do the Wright Screen" colorectal cancer screening project. "The...

Agreement Signed for Anti-Cancer Treatment.
August 8, 2000... 2000 AUG 8 - (NewsRx.com) -- SmithKline Beecham (SB) (SBH), Philadelphia, Pennsylvania, and Taiho Pharmaceutical Company Ltd. announced an agreement under which SB has been granted rights to Taiho's TAS106, a compound with a novel...

Collaboration Aims to Develop a Cancer Vaccine.
August 8, 2000... 2000 AUG 8 - (NewsRx.com) -- Viragen, Inc. (VRA), Plantation, Florida, announced that its subsidiary, Viragen (Scotland) Ltd., (VSL), in collaboration with the University of Nottingham and Cancer Research Campaign Technology (CRCT), has...

Patient Wants Access to Quarantined Vaccine.
August 8, 2000... 2000 AUG 8 - (NewsRx.com) -- A woman suffering from melanoma wants to be allowed to continue treatments with an experimental vaccine used during trials that were shut down by the U.S. federal government at the University of Oklahoma...

Efficacy Study Begins in Patients with Hepatocellular Carcinoma.
August 8, 2000... 2000 AUG 8 - (NewsRx.com) -- Tularik Inc. (TLRK), San Francisco, California, announced the initiation of a Phase I/II efficacy study for its anti-cancer drug candidate, T67, in patients with hepatocellular carcinoma (HCC). T67 has a...

ACIS Used in Collaborative Study to Detect Circulating Cancer Cells in Blood Stream.
August 8, 2000... 2000 AUG 8 - (NewsRx.com) -- ChromaVision Medical Systems, Inc. (CVSN), manufacturer of the Automated Cellular Imaging System (ACIS), announced that the University of California has awarded a research grant for a public/private...

Phase I GPI-0100 Vaccine Trial Initiated.
August 8, 2000... 2000 AUG 8 - (NewsRx.com) -- Galenica Pharmaceuticals, Frederick, Maryland, announced the beginning of a Phase I human clinical trial of GPI-0100 under an agreement with Memorial Sloan Kettering Cancer Center (MSKCC). The trial will...

Gene 'Shaving' Could Help Doctors Predict Treatment Efficacies.
August 15, 2000... 2000 AUG 15 - (NewsRx.com) -- A new statistical method that identifies similar groups of genes from large tissue samples could be used by health care professionals to predict the effectiveness of treating patients suffering from a variety...

Study on Chromosome Ends May Aid Cancer Research.
August 15, 2000... 2000 AUG 15 - (NewsRx.com) -- A Princeton University scientist has discovered a mechanism that cells use to control the length of their chromosome ends, a process that is thought to go awry in cancer. The finding, reported in the...

Radiation Therapy Offers Safe, Effective Alternative to Surgical Treatment.
August 15, 2000... 2000 AUG 15 - (NewsRx.com) -- Findings from a study from the University of Florida College of Medicine indicate that of the treatment options for tonsillar cancer, irradiation offers a similar chance of cure and a lower risk of...

Auditory Brain Stem Response Used for Screening.
August 15, 2000... 2000 AUG 15 - (NewsRx.com) -- The auditory brain stem response (ABR) has been used to detect small tumors, but recent criticisms have labeled it an insensitive measure, prompting researchers to evaluate its efficacy in small tumor...

Cigarette Smoking Increases Risk.
August 15, 2000... 2000 AUG 15 - (NewsRx.com) -- Men and women who smoke have an increased risk of developing bladder cancer, according to a team of researchers from Maastricht University in The Netherlands. In a systematic review published in the...

Computer Offers a Second Opinion on Chest Radiographs.
August 15, 2000... 2000 AUG 15 - (NewsRx.com) -- In a study comparing the effectiveness of neural network software and experienced human observers, three Boston, Massachusetts, radiologists have found that the computer makes an excellent consultant in cases...

Depression or Low Performance Status Predict Reduced Quality of Life After Treatment.
August 15, 2000... 2000 AUG 15 - (NewsRx.com) -- Special attention should be given to head and neck cancer patients who exhibit depressive symptoms or a low performance status, researchers recommend, because these patients are at specific risk for physical...

Radical Initial Surgery for Fibrous Histioctyoma Recommended.
August 15, 2000... 2000 AUG 15 - (NewsRx.com) -- Researchers in the People's Republic of China recommend radical surgery to prevent local recurrence of head and neck malignant fibrous histiocytoma. X.X. Wu and colleagues at the Chinese Academy of...

Chemokine Production and Tumor-Associated Immune Cells Arise in the Pancreas.
August 15, 2000... 2000 AUG 15 - (NewsRx.com) -- In vitro analysis of pancreatic cancer cells strongly suggests that chemokine expression occurs in the pancreas and that such expression might contribute to an increased presence of "tumor-associated immune...

New Minimally Invasive Procedure Spares Patient Loss of Esophagus.
August 15, 2000... 2000 AUG 15 - (NewsRx.com) -- Doctors at the University of Illinois at Chicago Medical Center have used a minimally invasive procedure to remove an early-stage esophageal cancer, sparing the patient, a 72-year-old woman, from major...

Delay in Diagnosis Does Not Impact Extent of Disease.
August 15, 2000... 2000 AUG 15 - (NewsRx.com) -- Despite public policy initiatives to increase cancer awareness, patients are delaying diagnosis of some head and neck cancers. A new study suggests, however, that the delay has not proven to have an...

Botulinum Toxin Helps Patients Speak After Surgery.
August 15, 2000... 2000 AUG 15 - (NewsRx.com) -- A new study from the M.D. Anderson Cancer Center in Houston, Texas, provides objective data that Botulinum toxin (Botox) injection offers a simpler and effective method of treatment for a select group of...

Study Finds Chemotherapy Followed by Surgery is No More Effective than Surgery Alone.
August 15, 2000... 2000 AUG 15 - (NewsRx.com) -- The results of a randomized trial conducted by a team of head and neck surgeons in Italy indicate that a combined chemo-surgical approach for the treatment of oral cavity cancer does not offer an increased...

Recurrence Risk Higher in Elderly Patients and Those Opting for Partial Thyroidectomy.
August 15, 2000... 2000 AUG 15 - (NewsRx.com) -- Elderly patients who have thyroid cancer and those electing to have a partial-thyroidectomy are at higher risk for cancer recurrence, according to a study by researchers at the M.D. Anderson Cancer Center in...

Combined Immunogene Therapy Induces Antitumor Response.
August 15, 2000... 2000 AUG 15 - (NewsRx.com) -- Immunogene therapy combining interleukin (IL-2) and IL-12 resulted in effective anti-tumor responses in murine models. "Although IL-2 and IL-12 are the most crucial cytokines used to induce potent...

Intrathecal Betamethasone Injections Effective.
August 15, 2000... 2000 AUG 15 - (NewsRx.com) -- Low-dose intrathecal injections of betamethasone can provide safe, effective, and long-lasting relief of intractable pelvic cancer pain, researchers report. "Steroids are administered systematically in...

Ketamine Can Relieve Neuropathic Pain.
August 15, 2000... 2000 AUG 15 - (NewsRx.com) -- Low doses of ketamine can provide effective relief for neuropathic cancer pain without the side effects usually associated with the drug, researchers report. "Ketamine, an NMDA receptor antagonist, has...

Reaction of Lymphoma Cells to Anti-CD20 Monoclonal Antibody Evaluated.
August 15, 2000... 2000 AUG 15 - (NewsRx.com) -- Researchers in Italy found that CD55 and CD59 cells are important regulators of complement-mediated cytotoxicity following treatment of B lymphoma cells with the monoclonal antibody (MAb) rituximab. "The...

Bombesin/Gastric-Releasing Peptide Receptors Seen on Human Ovarian Tumors.
August 15, 2000... 2000 AUG 15 - (NewsRx.com) -- Government researchers at the Veterans Affairs Medical Center in New Orleans, Louisiana, say that special receptors for growth factors that cause cancer can be found on ovarian cancer tumors. Antagonists...

U.K. Cancer Research Network to be Established.
August 15, 2000... 2000 AUG 15 - (NewsRx.com) -- Alan Milburn, U.K. Secretary of State for Health, July 28, 2000, began the roll-out of the National Health Service (NHS) Plan with details of the NHS Cancer Research Network, providing formal integration of...

Cancer Drug, Gene Therapy Promising.
August 15, 2000... 2000 AUG 15 - (NewsRx.com) -- A combination of gene therapy and drugs is showing promise in treating head and neck cancers, researchers in Texas report. If borne out in further trials, the findings could point the way to more...

Human Monoclonal Antibody-Based Treatment Results Reported.
August 15, 2000... 2000 AUG 15 - (NewsRx.com) -- The University of Nebraska Medical Center and Intracel announced that they have demonstrated the safety and feasibility of its HumaRAD product, a fully human monoclonal antibody-based product being developed...

Negative Immunomagnetic Purging Reduces Breast Cancer Tumor Cell Contamination.
August 15, 2000... 2000 AUG 15 - (NewsRx.com) -- Researchers in Italy found that negative immunomagnetic purging of peripheral blood stem cell harvests from breast cancer patients reduced tumor cell contamination without affecting hematopoietic recovery in...

Genetic "Signature" May Explain Why Deadly Skin Cancers Spread.
August 15, 2000... 2000 AUG 15 - (NewsRx.com) -- An international team led by scientists at the National Human Genome Research Institute (NHGRI) at the U.S. National Institutes of Health (NIH) has discovered a genetic "signature" that may help explain how...

Drug Study Defines Maximum Tolerated Chemotherapy Doses.
August 15, 2000... 2000 AUG 15 - (NewsRx.com) -- Advanced neuroblastoma, a type of cancer that often affects pediatric patients, is often treated with a variety of chemotherapy agents. Unfortunately, these drugs can be toxic and have adverse side affects at...

Thymidine Kinase Gene Therapy Well Tolerated in Patients.
August 15, 2000... 2000 AUG 15 - (NewsRx.com) -- A clinical trial of thymidine kinase suicide gene therapy with concomitant topotecan chemotherapy showed that the treatment was well tolerated in ovarian cancer patients. "Patients with recurrent ovarian...

Many Cancer Patients Use Complementary, Alternative Therapies to Supplement Primary Treatment.
August 29, 2000... 2000 AUG 29 - (NewsRx.com) -- Cancer patients who use or have an interest in complementary and alternative medicine (CAM) exhibit active coping behavior with regard to their disease, rather than signs of distress or poor compliance with...