Cancer Weekly articles from April 2003

Cancer Weekly archives from April 2003

NIST, UW-Madison research may lead to new breast cancer detection methods.(National Institute of Standards and Technology)(Brief Article)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Other than skin cancer, breast cancer is the most common type of cancer among women in the United States. More than 180,000 women are diagnosed with breast cancer each year. Research has led to...

Thrombin generation correlates with biomarkers in advanced prostate cancer.
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Thrombin generation correlates with biomarkers in advanced prostate cancer. According to recent research from the United States, "thrombin generation is increased in men with advanced prostate...

Pulmonary metastasis can arise after surgery for osteosarcoma.
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Pulmonary metastasis can arise after surgery for osteosarcoma. According to recent research from Japan, "early relapse with distant metastasis often is observed in patients with cancer after...

Disruption of the HIC1 gene may predispose mice to gender-specific malignancy.(Brief Article)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Disruption of the HIC1 gene may predispose mice to gender-specific malignancy "The gene hypermethylated in cancer-1 (HIC1) encodes a zinc-finger transcription factor that belongs to a group of...

Potential blood test could predict risk.(for colorectal cancer)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Johns Hopkins scientists have found a way to predict, with a simple blood test, which people may be at higher-than-normal risk for the most common form of colon cancer. The research, described in...

Gene that drives apoptosis also plays key role in development of skeletal muscle.(rhabdomyosarcoma development)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Investigators at St. Jude Children's Research Hospital have discovered that a protein causing mature cells to commit suicide also helps primitive muscle cells called myoblasts fuse together, allowing...

Bone marrow grafts may be best option with matched unrelated donors.(acute lymphoblastic leukemia )
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Bone marrow grafts may be the best choice for acute lymphoblastic leukemia (ALL) patients with HLA-identical but unrelated stem cell donors. Researchers from France "analyzed data for 213 patients...

An unusual case of microcystic adnexal carcinoma described.(skin cancer)(Brief Article)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- An unusual case of microcystic adnexal carcinoma is described. According to recent research from England, "Microcystic adnexal carcinoma (MAC) is an uncommon, recently described cutaneous adnexal...

Anthrapyridazone derivatives are active, even on multidrug resistant cells.(leukemia treatment)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Anthrapyridazone derivatives are active, even on multidrug resistant cells. According to recent research from Poland, "A series of anthrapyridazone derivatives with 1-2 basic side chains at various...

CTLA-4 exon 1 polymorphism G was found in leukemic hemolytic anemia patients.
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- CTLA-4 exon 1 polymorphism G was found in leukemic hemolytic anemia patients. "CTLA-4 is a CD28 homologue that plays an important role in negative regulation of T-cell responses. Its transient...

CMV disease can mimic an acute B-precursor lymphoblastic leukemia.(cytomegalovirus)(Brief Article)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- CMV disease can mimic an acute B-precursor lymphoblastic leukemia. "Hematogones (B-lymphocyte progenitor-precursor cells) are normal bone marrow constituents which are morphologically distinct...

A serum test is more consistently reliable than the standard urine test.(multiple myeloma diagnosis)(Brief Article)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- A serum test is more consistently reliable than the standard urine test. "Bence Jones protein in urine (immunoglobulin free light-chains) is characteristic of light-chain multiple myeloma. We...

The alcaloid swainsonine has a significant stimulatory effect on bone marrow.(Brief Article)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- The alcaloid swainsonine has a significant stimulatory effect on bone marrow. "The immunomodulatory alkaloid swainsonine (8alphabeta-indolizidine-1alpha,2alpha,8beta-triol) has potential for...

Migration of mutagens/carcinogens from PET bottles to water found.(polyethylene terephthalate )
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Migration of mutagens/carcinogens from polyethylene terephthalate bottles to the water they contain has been found. According to a study from Italy, "This study monitored the release of...

Injection of DTI-015, a mix of BCNU in ethanol, stabilized active gliomas.
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Injection of DTI-015, a mix of BCNU in ethanol, stabilized active gliomas. "DTI-015 (BCNU in 100% ethanol) utilizes solvent facilitated perfusion for the intratumoral treatment of gliomas. The...

Differentiating demyelinating lesion from neoplasm requires caution.(brain tumor)(Brief Article)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Differentiating demyelinating lesion from neoplasm requires caution. According to recent research from the United States, "Tumefactive demyelinating lesions can present with features similar,...

Data provide evidence of how to conduct web-based interventions.(breast cancer risk notification)(Brief Article)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Data provide evidence of how to conduct web-based interventions. "The Internet might transform the way in which health information is communicated to patients and general populations. Understanding...

Doppler imaging may have value for differentiating focal breast lesions.
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Doppler imaging may have value for differentiating focal breast lesions. "The purpose of this article is to demonstrate the diagnostic impact of ultrasound (US) in differentiating focal breast...

Incidence of "lobular" disease increasing.(lobular breast cancer)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- The incidence of lobular breast cancer has increased steadily from 1987 to 1999, according to a new report. Previous studies have shown that ever use or current use of combined estrogen and...

Local recurrence before 2 years following surgery predicts the worst outcome.(breast cancer)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Local recurrence before 2 years following surgery predicts the worst outcome. According to a study from England, "Local recurrence of cancer in the treated breast following breast conserving surgery...

Metastasis and tumor growth suppression achieved with propolis in mouse model.(breast cancer with lung metastasis)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Metastasis and tumor growth suppression achieved with propolis in mouse model. According to recent research from Croatia, "The antimetastatic efficacy of a water soluble derivative of propolis...

New technologies improve ability to diagnose and excise breast cancer.(Brief Article)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- New technologies have improved the ability to diagnose and excise breast cancer. According to a study from the United States, "Until recently little advance in the diagnosis and excision of breast...

Researchers call for better studies on environmental links.(breast cancer)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- A much broader net needs to be cast in the search for environmental links to breast cancer, concludes a new report that stems from a landmark gathering last year of researchers, public health officials,...

State variation in mortality rates due to later stage at presentation.(breast cancer)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- State variation in mortality rates was due to later stage at presentation. "In 2001 approximately 40000 deaths from breast cancer will occur in the United States. Although some estimates suggest...

Tamoxifen and a farnesyl transferase inhibitor can have synergistic effects.(breast cancer)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Tamoxifen and a farnesyl transferase inhibitor can have synergistic effects. "Farnesyl transferase inhibitors (FTIs) serve to specifically inhibit farnesyl isoprenoid lipid modification of proteins....

The biology of breast cancer genes will impact disease management.(Brief Article)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- The biology of breast cancer genes will impact disease management. According to recent research from the United States, "The biology of breast carcinoma is complex, with multiple factors...

Thymidylate synthase and thymidine are valid markers for selecting therapy.(for breast cancer)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Thymidylate synthase and thymidine are valid markers for selecting breast cancer therapy. According to a study from Japan, "thymidine phosphorylase (dThdPase) is identical to platelet-derived...

Axillary lymph node drainage appears to be an important prognostic factor.(breast cancer)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Axillary lymph node drainage appears to be an important prognostic factor. According to recent research from Hungary, "Axillary lymph node staging is an important prognostic factor in patients with...

Case report: Metastatic metamorphopsia of the right eye.(Brief Article)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- According to recent research from France, "We report the case of a 46-year-old woman, with no prior medical history, who developed a metamorphopsia of the right eye, followed by visual impairment." ...

Lung transplantation for bronchogenic carcinoma is not supported.(Brief Article)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Lung transplantation for bronchogenic carcinoma is not supported. "Experience with lung transplantation for bronchogenic carcinoma is limited. In our experience, three of six patients died of...

Expression of BCA-1 may influence tumor development and localization to CNS.(central nervous system )
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Expression of BCA-1 may influence tumor development and localization to the central nervous system. According to a study from the United States, "Primary central nervous system lymphoma (PCNSL) is...

The estrogen product 2-methoxyestradiol is a promising anticancer agent.
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- The estrogen product 2-methoxyestradiol is a promising anticancer agent. "Estrogens occurring naturally in the body are metabolized to catecholestrogens (2- and 4-hydroxyestradiol) by the cytochrome...

Peptide fusion improves the efficacy of thymidine kinase suicide gene therapy.
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Peptide fusion improves the efficacy of thymidine kinase suicide gene therapy. According to recent research from Italy, "suicide gene therapy using herpes simplex virus type-1 (HSV-1) thymidine...

Docetaxel enhances the effect of the angiogenesis inhibitor TNP-470.
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Docetaxel enhances the effect of the angiogenesis inhibitor TNP-470. "We demonstrated recently that chronic frequent administration of an adequate biological dose of the angiogenesis inhibitor...

Neck lymph node metastasis risk relates to ill defined extracapsular spread.
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Neck lymph node metastasis risk relates to ill defined extracapsular spread. According to recent research from England, "The prognostic significance of extracapsular spread of cervical metastases in...

Behavior changes could sharply cut cancer death rates.
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Stepped-up efforts to help people quit smoking, lose weight, and change other unhealthy behaviors could lead to a 29% decline in U.S. cancer death rates by 2015, according to a report issued by the...

Thromboembolism precedes cancer; should be considered risk marker.
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Thromboembolism precedes cancer; it should be considered a marker for risk. According to a study from the United States, "Thromboembolic (TE) events preceding cancer have been observed. Some...

CD40-directed gene therapy shows prospects for treating human cancers.
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- CD40-directed gene therapy shows prospects for treating human cancers. According to a study from the United States, "CD40, a member of the tumor necrosis factor receptor (TNF-R) family, is a surface...

Fruit fly metalloproteinase controls tissue remodeling, not embryo development.(Brief Article)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Fruit fly matrix metalloproteinase fosters tissue remodeling, not embryo development. "The matrix metalloproteinase (MMP) family is heavily implicated in many diseases, including cancer. The...

Men more likely to be screened for prostate than for colorectal cancer.
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Prostate cancer screening is more common than colorectal screening for men in the United States, according to a new study. But if practice were in accordance with evidence of screening-related...

Cyclooxygenase inhibitors decrease the angiogenic potential of tumor cells.(Brief Article)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Cyclooxygenase inhibitors decrease the angiogenic potential of tumor cells. "It seems certain that cyclooxygenase-2(COX-2) is related to tumor and some data suggest that COX-2 might have relation to...

Plasminogen activators and captopril combine to diminish angiogenesis in tumors.
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Plasminogen activators, when combined with captopril, increase antiangiogenic activity in the plasma of cancer patients, according to medical investigators at Beth Israel Deaconess Medical Center. ...

South Africa approves natural interferon.(hairy cell leukemia treatment)(Brief Article)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Viragen, Inc., (VRA) and Viragen International, Inc., (VGNI) announced the approval of its natural human alpha interferon for sale in South Africa. The South African regulatory authorities approved...

Cancer treated using vaccines in mixed allogeneic bone marrow chimeras.
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Successful therapy of metastatic cancer was achieved using tumor vaccines in mixed allogeneic bone marrow chimeras. According to a study from the United States, "A frequent outcome of allogeneic...

Researchers report a thymic carcinoid mimicking acute aortic dissection.(Brief Article)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Researchers report a thymic carcinoid mimicking acute aortic dissection. According to recent research from England, "Thymic carcinoids are extremely rare." "We present an 80-year-old...

Nuclear phosphatase and tensin homologue is associated with G0-G1.(Brief Article)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Nuclear phosphatase and tensin homologue is associated with G0-G1. According to recent research from the United States, "Phosphatase and tensin homologue deleted on chromosome 10 (PTEN) is a tumor...

A rare case of metastasis to the scalp from carcinoma of the cervix is presented.(Brief Article)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- A rare case of metastasis to the scalp from carcinoma of the cervix is presented. According to a study from South Korea, "Carcinoma of the cervix is a common neoplasm. Early detection and improved...

Common cell lines were analyzed cytogenetically for all aberrations.
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Common cell lines were analyzed cytogenetically for all aberrations. According to a study from the United States, "We applied a combination of molecular cytogenetic methods, including comparative...

Dendritic cell vaccine shows promise against cervical cancer.(Ampligen)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Vaccination with dendritic cells pulsed with tumor lysate and matured with a novel synthetic clinically nontoxic, double-stranded RNA analogue poly [I]:poly[C[subscript]12U] (Ampligen) induced a strong...

Growth of HeLa cells enhanced by H[subscript]2O[subscript]2 at relatively low concentrations.(Brief Article)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- The growth of HeLa cells was enhanced by H[subscript]2O[subscript]2 at relatively low concentrations. "In this paper, the effects of H[subscript]2O[subscript]2, a typical reactive oxygen species...

Antinausea drug will likely get approval in U.S.(Emend)(Brief Article)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Merck and Co.'s experimental treatment for preventing nausea and vomiting in chemotherapy patients won key support from a group of government advisers, meaning the drug will likely be approved for sale...

Older, younger febrile neutropenic patients have similar infection rates.
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Febrile neutropenic patients over age 60 have similar infection rates as younger patients. "We prospectively evaluated 131 consecutive episodes of fever and chemotherapy-induced neutropenia in 85...

Medical journal editorial dubs Gleevec "gold standard".(chronic myeloid leukemia treatment)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Gleevec is the new "gold standard" for treatment of chronic myeloid leukemia (CML), according to an editorial published in a leading medical journal. The editorial cites a study published in the...

Major study shows aspirin can reduce polyp return in GI cancer patients.(gastrointestinal cancer)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Patients who have had colorectal cancer may reduce their risk of suffering a recurrence by taking an aspirin daily, according to a new study conducted by a University of North Carolina at Chapel Hill...

Reduced syndecan-2 expression correlates with lower colon cancer tumorigenicity.
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Reduced syndecan-2 expression correlates with lower colon cancer tumorigenicity. "The inhibition of histone deacetylase activity is known to induce morphological changes of transformed cells. In...

Study explores genetic counseling in families with hereditary disease.(colon cancer genetics)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Among family members of patients with a certain type of hereditary colon cancer, only approximately half chose to undergo genetic testing, and many cited psychological and family issues as reasons for...

Tea complements drugs in treatment.(of colon tumors)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- A new study from the Linus Pauling Institute at Oregon State University (OSU) suggests that consumption of green and white tea can be just about as effective as use of the prescription drug sulindac in...

Western diet a chief culprit.(increased risk of colon cancer)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Women who fill their diets with red or processed meats, french fries, white bread, and sugary desserts may have an increased risk of colon cancer, according to a new study. Researchers followed...

Patients prefer "virtual" colonoscopy but dislike preparation.
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Surveying patients who were screened for colorectal cancer, investigators at the Siteman Cancer Center at Washington University School of Medicine and Barnes-Jewish Hospital in St. Louis found that most...

CDC study finds colorectal cancer screening rates remain low.(Centers for Disease Control and Prevention)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Although scientific evidence shows that more than one-third of deaths from colorectal cancer could be avoided if people aged 50 and older were screened regularly, American's screening rates remain low,...

Markers of susceptibility to some meat and caffeine carcinogens are found.
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Markers of susceptibility to some meat and caffeine carcinogens are found. According to a study from the United States, "Red meats cooked at high temperatures generate mutagenic heterocyclic amines,...

Screening tests effective and can save lives.(colorectal cancer screening)(Brief Article)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- A review of available scientific evidence supports the recommendation that all men and women aged 50 years or older undergo screening for colorectal cancer, but it does not support choosing one test...

Preparations can lead to kidney failure and the need for dialysis or transplant.(Chinese herb nephropathy)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Herbal preparations can lead to kidney failure and the need for dialysis or transplant. "A new renal disease called Chinese herb nephropathy (CHN) has been reported to occur in women who have...

A protein cluster links UVB and the induction of growth factor in skin cells.(ultraviolet B radiation)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- A protein cluster links UVB and the induction of growth factor in skin cells. "Chronic sun exposure of the skin has long been postulated to enhance cutaneous angiogenesis, resulting in highly...

New program to study possible environmental causes of cancer.(UCLA's Jonsson Cancer Center and the School of Public Health program)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- A new program at UCLA's Jonsson Cancer Center and the School of Public Health will seek to discover subtle variations in the human genetic blueprint that predispose some individuals to develop cancer...

Detecting random aneuploidy may predict tumor relapse.(Brief Article)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Detecting random aneuploidy may predict tumor relapse. According to a study from Israel, "To evaluate possible genomic instability and possible random aneuploidy, we applied comparative genomic...

Femur cancer treated with surgery, with or without radiation, worked best.
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Femur cancer treated with surgery, with or without radiation, worked best. According to a study from Italy, "The role of radiotherapy and/or surgery in the local treatment of Ewing sarcoma has still...

Rare case of malignant fibrous histiocytoma of the eyelid reported.(Brief Article)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- A rare case of malignant fibrous histiocytoma of the eyelid has been reported. According to recent research from France, "Fibrous histiocytomas, mostly benign, have often been reported in the orbit,...

RB1 mutation-screening method enhances care for the affected and saves money.(retinoblastoma)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- RB1 mutation-screening method enhances care for the affected and saves money. "Timely molecular diagnosis of RB1 mutations enables earlier treatment, lower risk, and better health outcomes for...

Foods and their heating or processing may increase cancer risk.(increase in breast, colon, and prostate cancer risk)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Foods themselves, and their heating or processing may increase cancer risk. According to recent research from Japan, "Food is an important factor in determining cancer incidence in many countries...

Researchers study the fungus Pulveroboletus ravenelii in mouse mammary culture.(Brief Article)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Researchers study the fungus Pulveroboletus ravenelii in mouse mammary culture. "Two new compounds, pulveraven A (1) and pulveraven B (2), as well as vulpinic acid (3) and its previously unreported...

The risk of cancer associated with virulent H. pylori may be underestimated.(Brief Article)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- The risk of cancer associated with virulent H. pylori may be underestimated. According to recent research from Sweden, "Helicobacter pylori is one of the most common pathogenic bacterial infections,...

Gastrointestinal disorders can affect the genitourinary system.(Brief Article)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Gastrointestinal disorders can affect the genitourinary system. According to recent research from the United States, "Gastrointestinal disorders may affect other organ systems; knowledge of these...

Vascular endothelial growth factor can be identified in digestive tumors.
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Vascular endothelial growth factor can be identified in digestive endocrine tumors. According to recent research from Italy, "angiogenesis, a process related to tumor growth and malignancy, is...

RNA interference may be more potent than antisense RNA in human cancer cells.
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- RNA interference may be more potent than antisense RNA in human cancer cells. According to recent research from Japan, " RNA interference (RNAi) is a newly discovered cellular pathway for the...

Antisense to cathepsin L impairs human brain tumor cell invasion.
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Antisense to cathepsin L impairs human brain tumor cell invasion. "Invasion and metastasis of certain tumors are accompanied by increased mRNA protein levels and enzymatic activity of cathepsin L....

Stripping proteoglycans of sulfation leads to adhesional and migrational changes.(glioma cell changes)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Stripping proteoglycans of sulfation leads to adhesional and migrational changes. According to recent research from Brazil, "Proteoglycans are considered to be important molecule in...

Congenital erythropoietic porphyria can occur with cystic hygroma.(Brief Article)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Congenital erythropoietic porphyria can occur with cystic hygroma. According to recent research from France, "Congenital erythropoietic porphyria (CEP) or Gunther disease is the rarest form of the...

Interleukin-18 binding protein therapy can neutralize cancer adhesiveness.(melanoma)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Interleukin-18 binding protein therapy can neutralize cancer adhesiveness Recent research from Spain "studied the role of endogenous IL-18 in hepatic metastasis by blocking this cytokine using the...

Global distribution is uneven, and annual disease mortality is same as incidence.(liver cancer demographics)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Liver cancer is a major worldwide problem, although some countries/regions/races/sexes are affected more than others. "Because of its high incidence in many of the most populous countries in the...

Human CRYL1 is an enzyme-crystallin found downregulated in some liver cancers.(crystallin, lambda 1)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Human CRYL1 is an enzyme-crystallin found downregulated in some liver cancers. According to a study from the People's Republic of China, "Lambda-crystallin is a composite of lens in rabbit and hare....

Researchers test vaccine in hopes of cutting cervical cancer rate.(Brief Article)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- Researchers at the University of Alabama at Birmingham (UAB) are joining the effort to test a vaccine that they hope will keep women from contracting human papillomavirus (HPV), a common infection that...

Possible association of verrucous scrotal carcinoma, hypospadias reported.(Brief Article)
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- There may be an association of verrucous scrotal carcinoma, hypospadias. According to a study from Italy, "We report a case of a locally advanced verrucous scrotal cancer in a patient with...

Viral gene responsible for oncogenesis identified.(Kaposi sarcoma associated herpes virus viral G-protein coupled receptor gene )
April 1, 2003... 2003 APR 1 - (NewsRx.com & NewsRx.net) -- The guilty gene responsible for initiating oncogenesis in Kaposi sarcoma has been identified - at last - by researchers at Weill Cornell Medical College. Kaposi sarcoma associated herpes virus...