Cancer Weekly articles from April 1993

Cancer Weekly archives from April 1993

New chemicals stop cancer from spreading. (carboxyamido-triazole) (U.S. National Cancer Institute)
April 5, 1993... U.S. NCI Scientists are developing an entirely new class of chemical weapons in their fight against cancer: medicines that stop the disease from spreading. Researchers from the U.S. National Cancer Institute (NCI) said they are...

Fatty diet tied to lung cancer. (in women) (U.S. National Cancer Institute)
April 5, 1993... U.S. NCI Eating lots of saturated fat, long considered taboo for its link with heart disease, now appears to raise the risk of lung cancer in women, government researchers report. The research, conducted by the U.S. National Cancer...

Self-help techniques to reduce cancer pain. (American Cancer Society)
April 5, 1993... American Cancer Society Researchers are studying whether self-help techniques can reduce cancer pain. Dr. Tim Ahles of the Center for Psycho-Oncology Research at Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, talked...

Research uncovers statistical links to skin cancer. (American Cancer Society)
April 5, 1993... American Cancer Society Factors as diverse as white collar employment and the use of diuretics have a statistical link to skin cancer, researchers told reporters at the American Cancer Society's Science Writers Seminar. The research...

New test measures extent of prostate cancer. (counting tiny blood vessels) (American Cancer Society)
April 5, 1993... American Cancer Society An experimental new test that counts tiny blood vessels may give doctors their first tool to predict whether prostate cancer is likely to spread and needs to be treated. The new test, which has not yet been...

Gene with possible links to drug resistance among cancer patients identified and cloned. (MCR-1) (American Chemical Society)
April 5, 1993... American Chemical Society A gene which may be the reason why thousands of cancer patients develop resistance each year to the popular cancer drug mitomycin C has been identified and cloned in the laboratory. The announcement was...

Chemists improve Taxol-like anticancer drug. (American Chemical Society)
April 5, 1993... American Chemical Society A synthetic, Taxol-like compound is more powerful than the natural product, Dr. Iwao Ojima of the State University of New York (SUNY) at Stony Brook reported at the American Chemical Society's 205th meeting in...

Research provides new tool to predict outcome, select therapy for childhood cancer. (TRK gene expression) (Washington University)
April 5, 1993... Washington University New understanding of neuroblastoma, a cancer afflicting children, has been presented in a research report in the March 25, 1993, issue of the New England Journal of Medicine by Dr. Garrett M. Brodeur and his...

Scientists identify fusion mechanism in cells. (SNARE proteins) (Memorial Sloan-Kettering Cancer Center)
April 5, 1993... Memorial Sloan-Kettering Cancer Center Researchers at Memorial Sloan-Kettering Cancer Center, New York, New York, have made a discovery that sheds light on the fundamental process by which vital substances are transported to their proper...

Results comparing two cancer imaging agents announced. (indium- vs. technetium-labeled monoclonal antibodies) (New Jersey)
April 5, 1993... New Jersey A presurgical clinical study comparing two colorectal cancer imaging agents was reported by Cytogen Corporation, Princeton, New Jersey, and its collaborators at the Eighth International Conference on Monoclonal Antibody...

Los Alamos study says brain cancer increase modest. (New Mexico)
April 5, 1993... New Mexico Los Alamos County, New Mexico, has had a modest increase in brain cancer cases, said a final report of a cancer rate study in Los Alamos, but it is not known whether the increase is due to an actual increase in the disease or...

Study to examine links between petrochemical industry, cancer. (Texas)
April 5, 1993... Texas A nine-month survey of cancer in Texas begins in April 1993 with financial backing by the Texas Institute for Advancement of Chemical Technology at Texas A&M University. "We felt it was time to obtain the best possible...

Immunohistochemical p53 in hepatocellular carcinoma and liver cell dysplasia. (Research Report)
April 5, 1993... AUTHORS: C. Cohen and P.B. DeRose. Emory University School of Medicine, Atlanta, Georgia. According to an abstract submitted by the authors to the 82nd Annual Meeting of the United States and Canadian Academy of Pathology, held March...

High prevalence of Epstein-Barr virus (EBV) in the Reed-Sternberg cells of Hodgkin's disease (HD) occurring in Peru. (Research Report)
April 5, 1993... AUTHORS: J. Lopategui( 1), K.L. Chang( 1), P.F. Albujar( 2), Y.Y. Chen( 1), R.M. Johnson( 1) and L.M. Weiss( 1). Departments of Pathology, (1)City of Hope National Medical Center, Duarte, California, and (2)University of Trujillo Hospital,...

Bone marrow involvement in large cell lymphoma: prognostic significance of discordant disease. (Research Report)
April 5, 1993... AUTHORS:." G.F.Hodges, T.M. Lenhardt and J.D. Cotelingam. Madigan Army Medical Center, Tacoma, Washington, and National Naval Medical Center, Bethesda, Maryland. According to an abstract submitted by the authors to the 82nd Annual...

Presentation of Ki-1 positive anaplastic large cell lymphoma in the central nervous system. (Research Report)
April 5, 1993... AUTHORS: D. Guinee and J. Beckstead. Department of Pathology, Oregon Health Sciences University, Portland, Oregon. According to an abstract submitted by the authors to the 82nd Annual Meeting of the United States and Canadian Academy of...

Pseudomesotheliomatous lung carcinoma: a rare asbestos-related malignancy readily separable from epithelial pleural mesothelioma. (Research Report)
April 5, 1993... AUTHORS: J.A. Robb, S.P. Hammar and H. Yokoo. Cedars Medical Center, Miami, Florida; Diagnostic Specialties Laboratory, Bremerton, Washington; and Veterans Administration Research Hospital, Chicago, Illinois. According to an abstract...

Neuroendocrine-like appearance of metastatic melanomas to lung. (Research Report)
April 5, 1993... AUTHORS: G. Sloop, E. Turbat-Herrera, J. Shultz, S. Hammar and G. Herrera. University of Alabama at Birmingham, Birmingham, Alabama, and Diagnostic Specialty Labs, Bremerton, Washington. According to an abstract submitted by the authors...

ATP bioluminescence chemosensitivity assay: leukemia studies. (Research Report)
April 5, 1993... AUTHORS: K. Becker and K. Herbst. Department of Medical Oncology and Hematology, Eppendorf University Hospital, Hamburg, Germany. According to an abstract submitted by the authors to the International Symposium on Emerging Clinical and...

ATP bioluminescence chemosensitivity assays: ovarian cancer. (Research Report)
April 5, 1993... AUTHORS: H. Bruckner. Department of Neoplastic Diseases and Medicine, Mount Sinai School of Medicine, New York, New York 10029. According to an abstract submitted by the author to the International Symposium on Emerging Clinical and...

Pretherapeutic in vitro testing in gynecological tumors: the use of the ATP-CSA (ATP-chemosensitivity assay). (Research Report)
April 5, 1993... AUTHORS: M. Untch, B.U. Sevin, J. Perras, R. Angioli, A. Untch and H. Hepp. Department Ob/Gyn, University of Munich, Germany; Department Gynecological Oncology, University of Miami, School of Medicine, Miami, Florida. According to an...

Screening and early detection of prostate cancer. (Periodical Report)
April 5, 1993... SOURCE: Cancer, February 1, 1993;71(3):981-983. Decision analysis may enable health workers to select a prostate cancer screening policy that best balances patient with cost effectiveness, says the author of this study. Gerald W....

Sexual rehabilitation after treatment for prostate cancer. (Periodical Report)
April 5, 1993... SOURCE: Cancer, February 1, 1993;71(2):1024-1030. Though the prostate gland is not necessary for normal sexual function, treatment for prostate cancer often exerts a profound influence on sexual capacities. This is the case, writes the...

Adjuvant therapy for localized prostate cancer. (Periodical Report)
April 5, 1993... SOURCE: Cancer, February 1, 1993;71(3):1005-1013. Prostate cancer patients with pelvic node involvement who received irradiation as definitive treatment benefited from adjuvant therapy with estramustine phosphate, report the authors of...

Is HIV infection associated with an increase in the prevalence of cervical neoplasia? (Periodical Report)
April 5, 1993... SOURCE: British Journal of Obstetrics and Gynaecology, February 1993;100(2):149-153. There is no association between HIV infection per se and cervical intraepithelial neoplasia (CIN), but such an association does seem to exist between...

The triphenylethylene drug tamoxifen is a strong liver carcinogen in the rat. (Periodical Report)
April 5, 1993... SOURCE: Carcinogenesis, February 1993;14(2):315-317. Tamoxifen is not safe for long term human use so long as its effects in rats cannot be shown to be irrelevant to human use, say the authors of this study. Gary M. Williams and...

Study of sunbathing habits in children and adolescents: application to the prevention of melanoma. (Periodical Report)
April 5, 1993... SOURCE: Dermatology, 1993;186(2):94-98. Using the number of sunburns and their severity as the criterion, a French study found that 10 percent of children (aged 3) and 45 percent of adolescents (ages 13 -14) were overexposed to the sun....

High-dose chemotherapy with autologous bone marrow rescue in advanced stage IV neuroblastoma. (Periodical Report)
April 5, 1993... SOURCE: European Journal of Cancer, 1993;29A(4):487-491. The efficacy of purging bone marrow in autologous transplantation is difficult to determine because of the very poor outcome of the therapy, say the authors of this French-Italian...

Epstein-Barr virus in angioimmunoblastic T-cell lymphomas. (Periodical Report)
April 5, 1993... SOURCE: Histopathology, February 1993;22(2):145-149. Epstein-Barr virus (EBV) is a consequence of angioimmunoblastic lymphadenopathy (AIL), rather than a cause, a British study concludes. EBV is noted for its oncogenic properties...

Utilities agree to study power lines near schools. (New York)
April 5, 1993... New York's eight utilities have agreed to conduct a first-in-the-nation survey of high voltage power lines near schools, state attorney general Robert Abrams said. Abrams said he requested the utilities conduct the survey after recent...

RU-486 may slow brain tumors. (University of Southern California)
April 12, 1993... University of Southern California The French abortion pill RU-486 appears to produce modest but encouraging improvement in some patients with inoperable brain tumors, a study has found. The pill's primary use is inducing abortions....

Follow-up after colorectal surgery may be unnecessary expense. (American Society of Colon and Rectal Surgeons)
April 12, 1993... ASCRS While adding significantly to cost of care, regular follow-up every three to six months after colorectal cancer surgery benefits a few patients but may be unnecessary in many cases. According to a report by a team of German...

Access to healthcare may be deciding factor in lung cancer. (Washington University)
April 12, 1993... Washington University Blacks are more likely to get lung cancer than whites and less likely to survive it, says a researcher who believes the difference may lie in social factors, including access to healthcare. Mary Graham, a...

Agency calls for radon testing in U.S. homes. (U.S. Environmental Protection Agency)
April 12, 1993... U.S. EPA The U.S. Environmental Protection Agency (EPA) has issued recommendations advising home buyers to ask for radon test results and to inquire as to whether the house they are buying has a radon reduction system. Radon is a...

Scientists report first anticancer gene therapy. (disarming neu oncogene) (California/Texas)
April 12, 1993... California/Texas Scientists have developed the first medicines intended to stop malignancy by disarming a rogue cancer gene, an approach that could help control many forms of tumors. The new treatment is intended to block an...

Studies show new way to diagnose breast cancer. (magnetic resonance imaging) (Israel)
April 12, 1993... Israel A safe and comfortable screening method can detect breast cancer with such remarkable accuracy it may eventually replace the mammogram in diagnosing tumors, an Israeli researcher reported. "Magnetic resonance imaging (MRI) is...

Human clinical trials on potential leukemia treatment begins. (Argus Pharmaceuticals Inc.'s AR-623, intravenous formulation of tretinoin) (Texas)
April 12, 1993... Texas Argus Pharmaceuticals Inc., Houston, Texas, has begun human clinical trials on its anticancer compound, AR-623 (Tretinoin), I.V.) for the treatment of leukemia. The initial Phase I study, designed to determine safety and...

New warning on skin cancer issued. (World Health Organization)
April 12, 1993... WHO The number of cases of a potentially fatal form of skin cancer is increasing 5-10 percent per year in some countries, the World Health Organization (WHO) said. In the United States and Australia, this rise is because more...

Gene causing brain and spine tumors identified. (neurofibromatosis type 2) (U.S. National Institutes of Health)
April 12, 1993... U.S. NIH Researchers said they have identified a gene that causes brain and spinal cord tumors, enabling new research into treatment and prevention. Scientists said the gene is responsible for neurofibromatosis type 2 (NF2) which...

Enzo Biochem says pioneer patent on genetic antisense technology issued. (New York)
April 12, 1993... New York Enzo Biochem Inc., Farmingdale, New York, announced that the U.S. Patent and Trademark Office has issued a basic, pioneering patent involving genetic antisense technology, for which Enzo Biochem holds the rights. Enzo...

Imutec pursues program of Phase III clinical trials. (Imutec Corp.'s anti-cancer biopharmaceutical, Virulizin) (Canada)
April 12, 1993... Canada Imutec Corporation, Toronto, Canada, announced that its Medical Advisory Board has recommended a series of Phase III clinical trials to begin as soon as possible on three types of cancer, for the company's initial drug Virulizin -...

Animal models that mimic individual patient cancers announced. (AntiCancer Inc.)
April 12, 1993... AntiCancer Inc. AntiCancer Inc., San Diego, California, has developed mouse models of human cancer in which the patient's tumor is transplanted to the corresponding organ in immunodeficient mice that accept foreign tissue. ...

Clinical trials completed on new process for early detection of cervical cancer. (Pap Plus Speculoscopy) (California)
April 12, 1993... California Researchers announced that clinical trials completed on a new procedure, known as Speculoscopy, when performed in conjunction with a Pap smear, dramatically increases a medical practitioner's ability to detect abnormalities...

Brain lymphomas of immunocompetent and immunocompromised patients: study of association with Epstein-Barr virus (EBV). (Research Report )
April 12, 1993... AUTHORS: F.D. Deamant( 1), K.L. Chang( 1), N. Flaris( 2), W.F. Hickey( 2) and L.M. Weiss( 1). Departments of Pathology, (1)City of Hope National Medical Center, Duarte, California; (2)Washington University Medical Center, St. Louis, Missouri....

p53 and K-ras mutations in different types of malignant pancreatic tumors. (Research Report)
April 12, 1993... AUTHORS: N.S. Pellegata, F. Sessa, B. Renault, M. Bonato, E. Silini, E. Solcia and G.N. Ranzani. University and IRCCS S. Matteo Hospital, Pavia, Italy. According to an abstract submitted by the authors to the 82nd Annual Meeting of the...

Hodgkin's disease (HD) following non-Hodgkin's lymphoma (NHL). (Research Report)
April 12, 1993... AUTHORS: D.W. Kingma( 1), L.J. Medeiros( 1), A. Zarate -Osorno( 1), D.L. Longo( 1), R.F. Ambinder( 2) and E.S. Jaffe( 1). (1)National Cancer Institute, Bethesda, Maryland, and (2)The Johns Hopkins Medical Institutions, Baltimore, Maryland....

Overexpression of the p53 tumor suppressor protein in primary lung adenocarcinomas is associated with cigarette smoking. (Research Report)
April 12, 1993... AUTHORS: W.H. Westra, G.J.A. Offerhaus, S.N. Goodman, M. Polak, I.O. Baas and R.H. Hruban. The Johns Hopkins Medical Institutions, Baltimore, Maryland, and the Academic Medical Center, Amsterdam, The Netherlands." According to an...

Non-Hodgkin's lymphoma (NHL) involving the ovary: a clinicopathologic analysis of 39 cases. (Research Report)
April 12, 1993... AUTHORS: V. Monterroso, M.J. Merino, E.S. Jaffe and L.J. Medeiros. National Cancer Institute, Bethesda, Maryland. According to an abstract submitted by the authors to the 82nd Annual Meeting of the United States and Canadian Academy of...

Clinical and FNA cytologic features of metastatic melanoma (MM) to the breast. (fine needle aspiration) (Research Report)
April 12, 1993... AUTHORS: J. Freeman, M.E. Corkill, J.K. Stephens and W. Robinson. University of Colorado Health Sciences Center, Denver, Colorado. According to an abstract submitted by the authors to the 82nd Annual Meeting of the United States and...

Metastatic ovarian cancer presenting as primary carcinoma of the breast. (Research Report)
April 12, 1993... AUTHORS: M. Merino, M. Roth and I.A. Lubensky. National Cancer Institute. Bethesda, Maryland. According to an abstract submitted by the authors to the 82nd Annual Meeting of the United States and Canadian Academy of Pathology, held...

High levels of p53 protein expression do not correlate with p53 gene mutations in CD30 (Ki-1) positive anaplastic large cell lymphoma (ALCL). (Research Report)
April 12, 1993... AUTHORS: E. Cesarman, G. Inghirami, A. Chadburn and D.M. Knowles. Columbia University, New York, New York. According to an abstract submitted by the authors to the 82nd Annual Meeting of the United States and Canadian Academy of...

Ceruloplasmin level in women with breast disease. (Periodical Report)
April 12, 1993... SOURCE: Acta OnCologica, 1992:31(8):843-846. Ceruloplasmin can be used as a tumor marker in follow-up of breast cancer patients, Turkish researchers say. Dr. *zg*r *zyilkan and colleagues at the Institute of Oncology, Hacettepe...

Repeated screening for carcinoma of the prostate by digital rectal examination in a randomly selected population. (Periodical Report)
April 12, 1993... SOURCE: Acta OnCologica, 1992;31(8):815-821. Digital rectal exam for prostate cancer can be implemented in a general practice in a manner that is cost-effective per potentially treatable cancer, Swedish researchers write. Current...

The value of prostate-specific antigen levels in pelvic lymph nodes for diagnosing metastatic spread of prostate cancer. (Periodical Report)
April 12, 1993... SOURCE: Canadian Journal of Surgery, February 1993;36(1):33-36. Measurement of the level of prostate-specific antigen (PSA) in nodal tissue is a good diagnostic tool, correlating well with histologic exam for metastatic prostate cancer,...

Prognostic factors for bone metastases in breast cancer. (Periodical Report)
April 12, 1993... SOURCE: International Orthopaedics, 1993;17(1):60-63. The attributes of enlarged lymph nodes form a useful predictor of bone metastases in breast cancer, two Spanish researchers suggest. M.A.D. Ulloa and E.C.R. Merchan of the...

Population-based cohort investigations of the risk for malignant tumors in first-degree relatives and wives of men with breast cancer. (Periodical Report)
April 12, 1993... SOURCE: Cancer, February 15, 1993;71(4):1273-1278. Female first-degree relatives of men with breast cancer run an increased risk of breast cancer and other genital tumors, while male first-degree relatives have a reduced risk for cancer,...

Analysis of Epstein-Barr virus in localized nasopharyngeal carcinoma tumors. (Periodical Report)
April 12, 1993... SOURCE: Cancer, February 15, 1993;71(4):1190-1192. Epstein-Barr virus (EBV) is found in the tumor tissue of patients with nasopharyngeal carcinoma (NPC) and in tumor-free tissue taken from the same patients, leading the authors of this...

Dietary carcinogens and the risk for glioma and meningioma in Germany. (Periodical Report)
April 12, 1993... SOURCE: International Journal of Cancer, February 20, 1993;53(4):561-565. N-nitroso compounds play an insignificant role in the cause of glioma or meningioma and, while an association does exist between glioma and the consumption of...

"AIDS Article Summaries" to be published. (newsletter from publisher Charles Henderson) (United States)
April 12, 1993... United States Charles Henderson, publisher of Cancer Weekly, announces the launch of AIDS Article Summaries, concentrating solely on summaries of AIDS-related articles from journals worldwide. "We decided that a monthly just did not...

Researchers find Taxol source in yew tree fungus. (Taxomyces andreanae) (Montana State University)
April 19, 1993... Montana State University Montana State University (MSU), Bozeman, Montana, scientists say they have found the cancer-fighting drug Taxol in a fungus seeping from a lone yew tree in northwestern Montana. "We have gone back to that...

Taxol researcher wins patent on new process to create cancer-fighting drug in the laboratory. (Dr. K.V. Rao) (University of Florida)
April 19, 1993... University of Florida The U.S. Patent and Trademark Office granted a patent to a University of Florida (UF) researcher for a unique process for the semi-synthesis of the cancer-fighting drug, Taxol. Dr. K.V. Rao, professor of...

New model to study cervical cancer. (Pennsylvania State University)
April 19, 1993... Pennsylvania State University Researchers here have found evidence supporting the belief that a papillomavirus - which normally causes harmless warts but has been linked to cervical cancer -may need an extra cellular push before it can...

Yeast may help stop cancer from spreading. (o-methyl cinnanamide, from Streptomyces griseoluteus) (Pennsylvania State University)
April 19, 1993... Pennsylvania State University Researchers at Pennsylvania State's Milton S. Hershey Medical Center have found that a compound purified from yeast, o-methyl cinnanamide, stopped several different kinds of cancer from invading other...

Sansum Clinic planning fetal cell transplants. (Russia/U.S.)
April 19, 1993... Russia/U.S. A research clinic hoping to avoid years of waiting signed a deal to obtain fetal tissue from Russia, now that President Clinton has lifted a moratorium on its use. "It will take a long time, at least three or four years,...

Smoking appears to reduce the risk of endometrial cancer. (U.S. National Cancer Institute)
April 19, 1993... U.S. NCI For some women, smoking appears to reduce the risk of endometrial cancer, a new study suggests. The study is reported in the February 1, 1993, issue of the American Journal of Epidemiology (released in April 1993),...

Scientists say mayapple plant could cure some cancers. (compound GL331, extract from mayapple, or mandrake) (University of North Carolina, Chapel Hill)
April 19, 1993... North Carolina University of North Carolina, Chapel Hill (UNC-CH), researchers and a California company have found that the mayapple plant could be used instead of a chemotherapy drug and might cure some cancers. The mayapple plant...

New treatments for lymphatic cancer no better than standard chemotherapy, study says. (Utah)
April 19, 1993... Utah Researchers were disappointed to find new drug combinations touted as promising treatment in some lymphatic cancers were no more effective than standard chemotherapy. "The results were disappointing in view of the lack of...

Medical center surgeon offers bladder-removal patients more options for normal lifestyle. (Dr. Thomas Ahlering; Indiana Pouch and Kock Pouch artificial bladders) (University of California, Irvine)
April 19, 1993... University of California, Irvine Internal artificial bladders may allow urinostomy patients greater freedom, a California surgeon says. Each year approximately 14,000 people are diagnosed with bladder cancer. Many have their...

Plastic surgeons' society tells what it knows about saline implants. (American Society of Plastic and Reconstructive Surgeons) (U.S. Food and Drug Administration)
April 19, 1993... U.S. FDA The American Society of Plastic and Reconstructive Surgeons (ASPRS) submitted information to the U.S. Food and Drug Administration (FDA) in accordance with a deadline to present comments on saline-filled breast implants. ...

ImmunoGen begins Phase III clinical trial of Oncolysin B. (Massachusetts)
April 19, 1993... Massachusetts ImmunoGen Inc., Cambridge, Massachusetts, announced the start of a multicenter, Phase III clinical trial of Oncolysin B, in patients with non-Hodgkin's B-cell lymphoma. The trial is designed to evaluate the effectiveness...

Alkermes announces commencement of RMP-7 clinical trials. (compound to help drugs cross the blood-brain barrier) (Massachusetts)
April 19, 1993... Massachusetts Alkermes Inc., Cambridge, Massachusetts, announced the commencement of two human clinical trials in the United States to evaluate the use of RMP*7 in patients with AIDS-related opportunistic infection of the central nervous...

New proteins for cancer therapy developed. (Single-Chain Antigen-Binding proteins, erbB-2 monoclonal antibody) (Enzon Inc., and Oncologix Inc.)
April 19, 1993... Enzon Inc., and Oncologix Inc. Enzon Inc. and Oncologix Inc. announced the signing of patent cross-licensing agreements relating to Enzon's Single-Chain Antigen-Binding (SCA) proteins and Oncologix's erbB-2 monoclonal antibody to develop...

Procrit (Epoetin alfa) indicated for the treatment of anemia in cancer patients on chemotherapy. (New Jersey)
April 19, 1993... New Jersey Procrit (Epoetin alfa), a recombinant human erythropoietin, is now indicated for the treatment of anemia caused by chemotherapy in patients with non -myeloid malignancies. In clinical studies, Procrit decreased blood...

Number of smokers increasing. (Bangladesh)
April 19, 1993... Bangladesh The number of smokers in Bangladesh is increasing, say health activists who assert that only prohibitive taxes will help the war against smoking. Nurul Islam of Adhunik, an anti-smoking group in Dhaka, is lobbying the...

Companies announce strategic alliance for oligonucleotide manufacturing technologies. (PerSeptive Biosystems Inc., Isis Pharmaceuticals Inc.)
April 19, 1993... PerSeptive Biosystems, Isis Pharmaceuticals Isis Pharmaceuticals Inc., Carlsbad, California, and PerSeptive Biosystems Inc., Cambridge, Massachusetts, jointly announced that they have signed a letter of intent covering the formation of a...

Cancer prevention and control research small grant program. (National Cancer Institute program announcement) (Research Report)
April 19, 1993... AUTHORS: PA Number: PA-93-070, National Cancer Institute, Bethesda, Maryland. "Application Receipt Dates: June 1 and October 1 of 1993, 1994 and 1995. Purpose: The National Cancer Institute (NCI) invites applications for small...

Perspective of the Cancer Immunology Branch, NCI. (National Cancer Institute) (Research Report)
April 19, 1993... AUTHORS: J.A. Sogn and F.C. Austin. National Cancer Institute, NIH, Bethesda, Maryland. According to an abstract presented by the authors to the Specific Immunotherapy of Cancer Vaccines Conference, held January 21-24, 1993, in...

Viral vector for induction of CTL. (cytotoxic T lymphocytes) (Research Report)
April 19, 1993... AUTHORS: E. Paoletti. Virogenetics Corporation, Rensselaer Technology Park, 465 Jordan Road, Troy, New York. According to an abstract presented by the author to the Specific Immunotherapy of Cancer Vaccines Conference, held January...

Active specific immunotherapy of murine colon adenocarcinoma with recombinant vaccinia/IL-2-infected tumor cell vaccines. (Research Report)
April 19, 1993... AUTHORS: J.A. Bash. Medical Laboratory Sciences, Florida International University, Miami, Florida. According to an abstract presented by the author to the Specific Immunotherapy of Cancer Vaccines Conference, held January 21-24, 1993,...

Cytotoxic T-cell control of Epstein-Barr virus positive malignancies. (Research Report)
April 19, 1993... AUTHORS: A. Rickinson( 1), J. Brooks( 1), S. Lee( 1), M. Kurilla( 2) and M. Rowe( 1). (1)CRC Laboratories, Department of Cancer Studies, University of Birmingham, Birmingham, B15 2TJ, U.K., and (2)Department of Pathology, University of...

Modulation of HTLV-I replication through CD2 and CD3 mediated activation of infected lymphocytes. (Research Report)
April 19, 1993... AUTHORS: D.J. Guyot, W. Harrington, L. Ratner and M. Larimore. The Ohio State University, Comprehensive Cancer Center and Department of Veterinary Pathobiology, Columbus Ohio; University of Miami, Florida; Washington University, Missouri. ...

Identification of a membrane antigen important for HTLV syncytia formation. (Research Report)
April 19, 1993... AUTHORS: M.G. Agadjanyan, K. Ugen, B. Wang, W.V. Williams and D.B. Weiner. The Wistar Institute and the University of Pennsylvania, Philadelphia. According to an abstract submitted by the authors to the Conference on Molecular...

Role of the sag gene in the mouse mammary tumor virus life cycle. (self-superantigen) (Research Report)
April 19, 1993... AUTHORS: T.V. Golovkina( 1), A. Chervonsky( 2), J. Prescott( 1) and S.R. Ross( 1). (1)University of Illinois, Chicago, Illinois; (2)Yale University School of Medicine, New Haven, Connecticut. According to an abstract submitted by the...

DES clear cell cancer-1992. (diethylstilbestrol) (Research Report)
April 19, 1993... AUTHORS: A.L. Herbst. University of Chicago, Chicago, Illinois. According to an abstract submitted by the author to the 24th Annual Meeting of the Society of Gynecologic Oncologists, held February 7-10, 1993, in Palm Desert, California,...