AIDS Weekly articles from October 2003

AIDS Weekly archives from October 2003

Leptin replacement can ameliorate protease inhibitor-induced lipid abnormalities.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Leptin replacement therapy can ameliorate the lipid dysfunction triggered by some anti-HIV drugs. "A major complication associated with the use of protease inhibitors (PIs) in treatment of...

Metal chelation underlies anti-HIV integrase activity of beta-diketo acids.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Metal chelation underlies the ability of beta-diketo acids (DKAs) to inhibit HIV integrase activity. DKAs "represent a major advance for anti-HIV-1 integrase drug development," scientists in the...

Antioxidant treatment may do more harm than good.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Antioxidant treatment may do more harm than good for patients with HIV-associated lipodystrophy. In a recent study from the United States, "ten HIV-infected nucleoside reverse transcriptase...

Caveolae used for HIV Tat fusion protein internalization.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Caveolae are used for cellular internalization of HIV Tat fusion proteins. "The Tat protein from HIV-1, when fused with heterologous proteins or peptides, can traverse cell membranes," scientists in...

To recruit cytoplasmic Tsg101, HIV Gag mimics human Hrs protein.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- The HIV Gag protein emulates the human Hrs protein in order to draw a key cytoplasmic factor to the endosomal membrane, where it can aid viral replication. HIV Gag "recruits the cellular factor...

Novel MKC-442 analogues show potent antiretroviral activity.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- A series of novel MKC-442 analogues have potent activity against both wild-type and MKC-442-resistant strains of HIV. According to a recent study from Denmark, "bis(alken-1-yloxy)methanes (2) were...

Smallpox vaccines may protect against HIV.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Smallpox vaccinations may also provide protection against the virus that causes AIDS, according to researchers at George Mason University. The findings are only preliminary and based on a very small...

Study will test antiviral drug tenofovir to prevent HIV infection.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- University of California San Francisco (UCSF) researchers have been funded by the U.S. National Institutes of Health to study the antiretroviral drug tenofovir as a potential pre-exposure prophylaxis in...

Incyte enters licensing agreement for a phase II HIV drug.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Incyte Corp. (INCY) and Pharmasset, Ltd., announced that they have entered into a collaborative licensing agreement to develop and commercialize the antiretroviral drug Reverset, also known as RVT,...

Study: Patients can benefit from simplified antiretroviral treatments.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- A large study shows that simplified antiretroviral treatment regimens containing Viramune (nevirapine) or efavirenz offer comparable efficacy and safety in patients who switched from a protease...

Up to 10,000 Ugandans with AIDS to receive antiretroviral medications.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- The Republic of Uganda's Minister of State for Health announced in Washington, DC, a groundbreaking initiative to offer life-extending antiretroviral (ARV) medications to as many as 10,000 Ugandans...

HIV researcher at Rush awarded grant from Doris Duke Foundation.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- The Doris Duke Foundation has awarded a 2-year, $200,000 grant to immunologist Alan Landay, PhD, from Rush University Medical Center in Chicago. The grant allows Landay and his international team of...

Mitochondrial DNA detector commercialized to mark adverse effects of therapy.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Primagen Holding B.V., a provider of molecular diagnostic tests for infectious diseases, AIDS, and cancer, has entered into an exclusive worldwide licensing agreement to commercialize the mitochondrial...

Scientists describe how HIV infection kills brain cells.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- People infected with the human immunodeficiency virus type 1 (HIV-1) may develop dementia due to the death of neurons in the brain. However, HIV-1 does not infect neurons, suggesting that an indirect...

Investigational protease inhibitor can be taken with Maalox TC, Zantac, or Lipitor.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Pharmacokinetic (PK) data from two clinical studies of the investigational HIV protease inhibitor (PI) 433908 (908) were presented at the 43rd Interscience Conference on Antimicrobial Agents and...

HIV-based vectors do not require rev gene.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- The rev gene does not need to be included in HIV-based gene therapy vectors. "HIV-1-based vectors are promising tools for gene therapy because of their ability to integrate into nondividing cells,"...

HIV-1 antibody tests approved for distribution in the Republic of Uganda.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Calypte Biomedical Corporation (CYPT), the developer and marketer of the only two U.S. Food and Drug Administration (FDA) approved HIV-1 antibody tests that can be used on urine samples, as well as an...

Genetically enhanced bacteria may prevent HIV infections in women.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Researchers at the Stanford University School of Medicine have found in laboratory experiments that bacteria that naturally live in the body can be genetically enhanced for potent antiviral activity,...

FDA approves venipuncture whole-blood claim for OraQuick HIV-1 antibody test.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- OraSure Technologies, Inc., (OSUR), an oral fluid diagnostics company, announced that its OraQuick Rapid HIV-1 Antibody Test has been approved by the U.S. Food and Drug Administration (FDA) for use in...

Study assessing abacavir in a once daily art regimen presented at ICAAC.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Studies supporting the efficacy of a once daily (QD) antiretroviral (ART) therapy regimen and the QD dosing of Ziagen (abacavir sulfate) (ABC) were presented at the 43rd Interscience Conference on...

DNA immunization enhances immune response to fowlpox-based SIVmac vaccine.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Prior DNA immunization enhances immune response to dominant and subdominant viral epitopes induced by a fowlpox-based SIVmac vaccine in long-term slow-progressor macaques infected with SIVmac251. ...

Consecutive HIV testing strategy suitable for use in developing countries.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- A consecutive testing strategy for HIV screening is suitable for use in developing areas. "Voluntary testing and counselling are accepted widely for the prevention of human immunodeficiency virus...

New HIV-1 enzyme immunoassay used to estimate HIV seroincidence.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Researchers list the performance characteristics of a new less sensitive HIV-1 enzyme immunoassay for use in estimating HIV seroincidence in a recent issue of the Journal of Acquired Immune Deficiency...

Lentiviral vectors can protect transduced cells from HIV infection.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- With the proper load, lentiviral vectors can protect transduced cells from HIV infection. "A primary advantage of lentiviral vectors is their ability to pass through the nuclear envelope into the...

Novel assay detects replication-competent lentiviral vectors.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- A novel assay can detect very low levels of lentiviral vector contamination with replication-competent pathogens. "Lentiviral vectors have demonstrated great potential as gene therapy vectors,...

Yeast-based HIV cloning system useful for research.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- A novel yeast-based viral cloning system may aid research on uncommon HIV subtypes and strains. According to recent research from the United States, "A recent shift from studies on a few subtype B...

Cytidine deaminase with potent but Vif-abolished antiretroviral activity identified.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- A novel endogenous enzyme has the potential to profoundly disrupt HIV replication. "A human gene with potent antiretroviral activity has recently been found to encode a new member of the family of...

Role of Tsg101 in HIV Gag trafficking and release clarified.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- The role of the Tsg101 protein in the trafficking and release of HIV Gag from infected cells has been clarified. "The structural precursor polyprotein of human immunodeficiency virus type 1,...

Through ESCRT recruitment, Hrs helps regulate endosomal multivesicular body formation.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- The Hrs protein helps regulate endosomal multivesicular body formation through ESCRT recruitment. "Hrs and the endosomal sorting complexes required for transport, ESCRT-I, -II, and -III, are...

Virus assembly takes place in late endosomes in HIV-infected primary macrophages.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Virus assembly takes place in late endosomes in HIV-infected primary macrophages. "Although human immunodeficiency virus type 1 (HIV-1) is generally thought to assemble at the plasma membrane of...

Successful negotiations by Zimbabwean women increase male condom use.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Researchers have identified successful negotiation strategies used by Zimbabwean women to increase the use of male condoms. According to a study from the United States, "One of the fundamental...

Baseline serum IL-7 levels do not predict immunologic HAART outcome.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Serum levels of the cytokine interleukin (IL)-7 have little prognostic value in HIV patients undergoing antiretroviral therapy. Baseline IL-7 level "has been proposed as a predictor of immunologic...

High-performance LC assay improves measurement of plasma tenofovir levels.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- A novel assay may help physicians monitor circulating levels of the antiretroviral agent tenofovir in HIV patients. According to published research from France, a "high-performance liquid...

Nuclear protein phosphatase-1 helps mediate HIV transcription.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Nuclear protein phosphatase-1 (PP1) appears to play a key role in the process of HIV transcription. Scientists in Washington, DC, previously demonstrated that PP1 "dephosphorylates RNA polymerase...

Prophylactic single-dose nevirapine linked to low rate of HIV V106M mutations.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- A low rate of HIV V106M mutations - usually associated with efavirenz treatment - has been observed in women treated with single-dose nevirapine as vertical transmission prophylaxis. "Nevirapine...

Some antiretroviral drugs induce PBMC P-glycoprotein expression.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Some anti-HIV agents can trigger the expression of drug efflux pumps by peripheral blood cells. "Several antiretroviral compounds have been shown to be substrates for the efflux protein...

T-cell apoptosis overwhelms proliferation during structured HIV treatment interruptions.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- T-cell apoptosis is much more extensive than T-cell proliferation during structured HIV treatment holidays. "Multiple failures of antiretroviral treatments, as a result of multidrug-resistant...

Vitamin A deficiency common in HIV, tuberculosis patients in Africa.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- In African patients, HIV and/or tuberculosis infections are associated with vitamin A deficiency. In a recent study from Tanzania, "serum vitamin A was determined" and compared in "100 HIV-positive...

AIDS vaccine protects against infection in a macaque AIDS model.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- A single DNA priming followed by a single booster with a recombinant replication-defective Sendai virus vector was protective in a macaque AIDS model. According to a study from Japan, "We previously...

KSHV transcription factor K-bZIP prolongs cell cycle transition in infected cells.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- The KSHV transcription factor K-bZIP prolongs cell cycle transition in infected cells. "In order to cope with hostile host environments, many viruses have developed strategies to perturb the...

PET scans could provide insight into HIV-1 progression.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- A recently published article and a research letter provide preliminary data suggesting that positron emission tomography (PET) scans could identify the effect of HIV-1 infection on the body's lymphatic...

Scientists invent search-and-destroy method to flush HIV out of hiding places.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- University of California Los Angeles AIDS Institute scientists have devised a new technique to switch on and drive hibernating HIV from its hiding places in the body. Reported in Immunity, the...

Molecular blood test suitable for CMV monitoring.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- A novel molecular blood test is suitable for monitoring cytomegalovirus infection. "The measurement of human cytomegalovirus (HCMV) DNA in blood is becoming the standard method for monitoring HCMV...

Acquisition offers company methods to fight bioterrorism.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Nutra Pharma Corp. (NPHC) has signed a letter of intent to acquire 100% of the capital stock of Infectech Inc. (IFEC) in a cash and stock transaction, providing Nutra Pharma with patented technologies...

T-cell costimulatory molecule function may determine PCP susceptibility.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- T-cell costimulatory molecule function may determine pneumonia susceptibility in HIV patients. "Loss of T-cell number and function during HIV infection or secondary to pharmacologic...

Are the rights of HIV-positive citizens adequately protected in Indian courts?
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- The legal system in India may not adequately protect citizens suffering from HIV infection. "It is believed that India will soon have the highest number of HIV/AIDS cases of any country,"...

Levin named to scientific advisory board at infectious disease firm.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Aethlon Medical, Inc., (AEMD) announced that Nathan W. Levin, MD, has been appointed to the company's science advisory board. Levin is the medical and research director of the Renal Research...

Role of HIV nucleocapsid protein zinc fingers in reverse transcription clarified.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- The role played by zinc fingers in the HIV nucleocapsid protein during reverse transcription has been clarified. "In the minus-strand transfer step of HIV-1 reverse transcription, the nucleocapsid...

Ubiquitin plays non-proteolytic role in HIV Tat-mediated viral transactivation.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Ubiquitin plays a non-proteolytic role in HIV Tat-mediated viral transactivation. "The human immunodeficiency virus type 1 (HIV-1) encodes a potent transactivator, Tat, which functions through...

Researchers continue AIDS vaccine research with $15 million grant.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- A team of medical researchers from three Seattle research facilities recently received a grant of more than $15 million from the National Institute of Allergy and Infectious Diseases (NIAID) to continue...

Routine gonorrhea, Chlamydia screening at HIV clinics may slow HIV spread.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Routine gonorrhea and Chlamydia screening at HIV clinics may help slow the spread of all three infections. "Because bacterial sexually transmitted diseases (STDs) facilitate HIV transmission,...

Sexually transmitted diseases treatment guidelines explained.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Two researchers explain the sexually transmitted diseases treatment guidelines released in 2002. "Sexually transmitted diseases (STDs) are a major health problem for adolescents. Health care...

Licensing deal signed with Gilead Sciences for smallpox drug.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Chimerix, Inc., an emerging biotechnology company developing orally available, targeted medicines from bioactive molecules, announced that it has licensed rights from Gilead Sciences, Inc., (GILD) to...

First report of combined spinal subdural tuberculous empyema and intramedullary tuberculoma.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- For the first time, a patient with combined spinal subdural tuberculous empyema and intramedullary tuberculoma has been reported. "Tuberculous involvement of the spinal subdural and intramedullary...

Hormonal contraceptives don't affect course of HIV infection.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Hormonal contraceptive use does not have a significant impact on the course of HIV infection. Physicians in the United States "compared the HIV-1 RNA and CD4 lymphocyte counts from users and...

Aberrant somatic hypermutation linked to AIDS-associated NHL development.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- Aberrant somatic hypermutation may play a key role in the development of AIDS-associated NHL. "The pathogenesis of AIDS-related non-Hodgkin lymphomas (AIDS-NHLs) is associated with chromosomal...

CCR5 and CXCR4 have distinct mechanisms of agonist-induced endocytosis.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- CCR5 and CXCR4 have distinct mechanisms of agonist-induced endocytosis. "Desensitization of the chemokine receptors, a large class of G protein-coupled receptors, is mediated in part by...

Caffeoyl naphthalenesulfonamide derivatives inhibit HIV integrase activity.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- A group of novel caffeoyl naphthalenesulfonamides inhibit HIV integrase (IN) activity. HIV-1 IN "is an essential enzyme for retroviral replication and a rational target for the design of anti-AIDS...

Switch maintenance may prevent lipodystrophy in NNRTI-treated HIV patients.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- Switch maintenance may prevent lipodystrophy in NNRTI-treated HIV patients. According to recent research from France, "Forty patients participating in the TRIZAL study were treated with a...

Phthalocyanines may prevent sexually transmitted HIV infection.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- Phthalocyanines may prevent sexually transmitted HIV infection According to published research from the United States, "The ability of selected phthalocyanines and metallophthalocyanines to block...

Protein grafting used to create anti-HIV epitope.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- An HIV-inhibiting epitope has been developed through the use of protein grafting. "Protein grafting, the transfer of a binding epitope of one ligand onto the surface of another protein, is a...

Despite increased attention, Africa's AIDS fight remains only half funded.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- Although an increasing number of leaders of African and donor nations are demonstrating a greater willingness to address HIV/AIDS in Africa, recent analyses show that the total funding anticipated is...

WHO vows to renew commitment to treating 3 million AIDS patients by 2005.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- In an effort to salvage at least one of the international community's goals to fight HIV/AIDS, the World Health Organization renewed its commitment to treat 3 million patients in poor countries by...

Studies to look at role of alcohol in HIV risk in heterosexual women.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- The relationship between drinking and HIV/AIDS in women will be the focus of studies to be conducted under two grants totaling $3.1 million awarded by the National Institute on Alcohol Abuse and...

Research: FUZEON-based regimens provide significant durable response.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- Eighty percent of patients receiving a FUZEON (enfuvirtide)-based anti-HIV drug regimen who achieved undetectable levels of the virus at 24 weeks maintained this response at 48 weeks, according to new...

Study: Kaletra regimen shows viral suppression for patients new to therapy.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- Study data showed the majority of patients initiating therapy with Abbott Laboratories' protease inhibitor (PI), Kaletra (lopinavir/ritonavir), as part of their treatment regimen achieved and...

HIV vaccine candidate trial begins in 18 cities around the world.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- The HIV Vaccine Trials Network (HVTN) and Merck & Co., Inc., announced that they have begun the first global clinical trial of Merck's HIV vaccine candidate in 18 cities around the world. The...

Dendritic cells respond to antigens through heat shock protein receptor.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- Disease-associated dendritic cells respond to disease-specific antigens through the common heat shock protein receptor. According to recent research published in the journal Blood, "The most...

Molecular diagnostic test manufacturer earns ISO 9001:2000 certification.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- Primagen Holding B.V., a provider of molecular diagnostic tests for infectious diseases, AIDS, and cancer, has earned full ISO (International Organization for Standardization) 9001:2000 certification....

HIV testing by obstetrics staff during labor & delivery is fast, accurate.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- Having obstetric staff perform rapid HIV testing on women while they are in labor provides accurate results much faster than sending testing specimens to the on-site hospital laboratory, according to a...

EnvirOx launches Critical Care containing Axenohl technology.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- Innovative Medical Services (PURE) announced that EnvirOx, LLC, of Danville, Illinois, has launched Critical Care, a new commercial disinfectant-fungicide-virucide, featuring Axen-30 as the active...

Anti-HIV mechanisms of SPMG clarified.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- The antiretroviral mechanisms of SPMG have been clarified. In a recent study from China, "The potential targets of marine sulfated polymannuroguluronate (SPMG) involved in inhibition of HIV-1...

CCR5 antagonists derived from fungus.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- A pair of novel CCR5 antagonists have been derived from a common fungus. According to published research from Singapore, "Two new compounds, 10-methoxydihydrofuscin (1) and fuscinarin (2), and one...

Pharmaceutical company raises $2.5M through a private placement.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- Adventrx Pharmaceuticals, Inc., (AVRX) announced that it has raised approximately $2.5 million through a private placement with institutional and accredited investors. The company issued...

NIH grant to fund Texas center for immunology and biodefense.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- Baylor Research Institute (BRI) announced that it has received a $14.6 million grant from the National Institute of Allergy and Infectious Disease (NIAID), one of the U.S. National Institutes of...

Intravaginal ring could be used in new approach to AIDS prevention.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- An intravaginal ring that releases antibiotics has been developed by scientists at Queen's University Belfast, Ireland. The ring will initially be used to treat a common vaginal infection, but it...

CDC study finds that OraQuick test provides fast results during labor.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- OraSure Technologies, Inc., (OSUR) announced that the use of its OraQuick Rapid HIV-1 Antibody Test at the point of care was found to provide testing results four-times faster than when the OraQuick...

Letter of intent received for $4M purchase of HIV tests.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- Calypte Biomedical Corporation (CYPT), the developer and marketer of the only two U.S. Food and Drug Administration (FDA) approved HIV-1 antibody tests that can be used on urine samples, as well as an...

Non-parametric methods can predict HIV drug susceptibility from genotype.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- Non-parametric methods have been devised to predict HIV drug susceptibility from the viral genotype "Medical management of HIV infection requires an understanding of the relationship between viral...

MAPK signaling needed for beta-chemokine production by CD40L-stimulated macrophages.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- MAPK signaling is needed for beta-chemokine production by CD40L-stimulated macrophages. "CD40 ligand is a cell surface molecule on CD4+ T cells that interacts with its receptor, CD40, on antigen...

Virological suppression in HIV patients linked to improved psychomotor speed.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- Virological suppression is linked to improved psychomotor speed in HIV patients. In a recent study, scientists in the United States "evaluated the association of a virologic response to highly...

High testis-specific transcriptional cyclin T1 promoter activity seen in animal model.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- High testis-specific transcriptional cyclin T1 promoter activity has been observed in transgenic mice. "The ubiquitously expressed cyclin T1 gene encodes for a protein involved in human...

High IL-7 levels linked to CD4 cell recovery in pediatric HIV patients.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- Elevated levels of the cytokine IL-7 are linked to CD4 cell recovery in pediatric HIV patients. According to published research from Spain, "To asses the role of interleukin 7 (IL-7) in the thymic...

LEDGF/p75 needed for nuclear and chromosomal targeting of HIV-1 integrase.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- LEDGF/p75 is needed for nuclear and chromosomal targeting of HIV-1 integrase in human cells. Previous research by scientists in Belgium revealed that HIV-1 IN "forms a specific nuclear complex with...