AIDS Weekly articles from November 2001

AIDS Weekly archives from November 2001

HIV Gp120 Increases Corticotropin Releasing Factor Secretion.(Brief Article)
November 5, 2001... 2001 NOV 5 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - The HIV coat protein gp120 triggers heightened levels of corticotropin release factor (CRF) production from hypothalamus cells, researchers in Italy report. ...

Abacavir Pharmacokinetics Unaffected By Renal Impairment.(Brief Article)
November 5, 2001... 2001 NOV 5 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Patients suffering from both HIV infection and kidney dysfunction can be treated with unmodified abacavir regimens, according to researchers in France. ...

HIV Infected People Need Not Carry AIDS Virus Long Before Passing It On.(Brief Article)
November 5, 2001... 2001 NOV 5 - (NewsRx.com & NewsRx.net) -- People who contract HIV, the virus that causes AIDS, can pass that virus on to others within a week or two of picking it up themselves, a new study conducted at the University of North Carolina at...

Clinical Trials Begin In Healthy Individuals At UC Davis.(Brief Article)
November 5, 2001... 2001 NOV 5 - (NewsRx.com & NewsRx.net) -- A clinical trial testing the safety and tolerability of two investigational AIDS vaccines for healthy individuals is being launched at the University of California Davis School of Medicine and Medical...

Immunoglobulins From Resistant Sex Workers May Provide Protection.(Brief Article)
November 5, 2001... 2001 NOV 5 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - HIV specific immunoglobulin from persistently uninfected sex workers may aid in the development of an HIV vaccine effective against a wide range of viral...

Hepatitis B Vaccine Response Falls Short In Youth, Those With HIV.(Brief Article)
November 5, 2001... 2001 NOV 5 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Older adolescents may not be fully protected after being vaccinated against hepatitis B virus. Furthermore, youth who are infected with human...

Coinfection Increases HIV Replication.(Brief Article)
November 5, 2001... 2001 NOV 5 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Patients infected with HIV and tuberculosis display higher levels of viral replication at coinfection sites, according to researchers in the United States. ...

Codiscoverer of AIDS Virus Joins Regent Group Research Consultant Team.(Brief Article)
November 5, 2001... 2001 NOV 5 - (NewsRx.com & NewsRx.net) -- Dr. Luc Montagnier, the world renowned virologist and codiscoverer of the virus that causes AIDS, has joined the research team of Millennium Biotechnologies Inc., a wholly owned subsidiary of Regent...

Voriconazole Effective Treatment Of Fungal Infections.(Brief Article)
November 5, 2001... 2001 NOV 5 - (NewsRx.com & NewsRx.net) -- Pfizer, Inc., said that an Advisory Committee to the U.S. Food and Drug Administration (FDA) unanimously recommended approval of both oral and intravenous formulations of voriconazole for the treatment...

Multikine Effective In HIV/HPV Infected Women.(Brief Article)
November 5, 2001... 2001 NOV 5 - (NewsRx.com & NewsRx.net) -- A presentation at the Annual Meeting of the International Society for Interferon and Cytokine Research in Cleveland, Ohio, by scientists from the Institute of Human Virology (IHV) and CEL-SCI suggests a...

TherImmune Awarded $4.5 Million For HIV Vaccine Development Services.(Brief Article)
November 5, 2001... 2001 NOV 5 - (NewsRx.com & NewsRx.net) -- TherImmune Research Corp. has been awarded a three-year $4.5 million HIV Vaccine Development Task Order from the U.S. National Institute of Allergy and Infectious Diseases (NIAID) Indefinite Delivery -...

ViroLogic Broadens Agreement With Roche and Trimeris For Technology Use.(Brief Article)
November 5, 2001... 2001 NOV 5 - (NewsRx.com & NewsRx.net) -- ViroLogic, Inc. has signed an expanded agreement with Hoffmann-La Roche, Inc. and Trimeris, Inc. to use ViroLogic's proprietary HIV resistance testing technology in the development of T-20 and T-1249,...

Chinese Newspaper Reports On HIV Infections Of 118 Villagers.(Brief Article)
November 5, 2001... 2001 NOV 5 - (NewsRx.com & NewsRx.net) -- In an unusual official look at China's AIDS epidemic, a state newspaper has reported 118 people in one village contracted the virus while selling blood. At least 10 of those infected have developed...

Cambridge Antibody Technology Announces Product Development Alliance With Merck.(Brief Article)
November 5, 2001... 2001 NOV 5 - (NewsRx.com & NewsRx.net) -- Cambridge Antibody Technology has entered into a collaboration and license agreement with Merck & Co. Inc. for the research and development of products specific for a key target involved in disease...

Early Cytotoxic T-Cell Responses May Be Key To Development.(Brief Article)
November 5, 2001... 2001 NOV 5 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Vaccines for HIV should harness the powerful cytotoxic T-lymphocyte (CTL) responses to the virus seen in the acute stages of infection, researchers in Wisconsin...

Elispot Assay May Hasten Development Of African Vaccine.(Brief Article)
November 5, 2001... 2001 NOV 5 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Enzyme-linked immunospot (Elispot) analysis of immune responses to HIV is aiding the development of a vaccine targeting viral strains common in Africa,...

HIV Infects Subset Of T Cells Leading To Depletion, Researchers Say.(Brief Article)
November 5, 2001... 2001 NOV 5 - (NewsRx.com & NewsRx.net) -- The battalion of CD4[superscript]+ T cells, which fight HIV and other pathogens, needs new recruits to replace the cells that fall. Researchers at the Gladstone Institute of Virology and Immunology...

Scientists Identify Mechanisms Of HIV Life Cycle.(Brief Article)
November 5, 2001... 2001 NOV 5 - (NewsRx.com & NewsRx.net) -- Myriad Genetics, Inc. and the University of Utah announced the publication of the results of pioneering research into molecular mechanisms essential for the life cycle of the human immunodeficiency...

Gag-Specific Helper T Cells Aid In Viral Control.(Brief Article)
November 12, 2001... 2001 NOV 12 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Helper T cells that recognize the HIV Gag protein play a significant role in the body's immune response to the virus, according to researchers in the United...

Gag Optimization Improves Immunogenicity.(Brief Article)
November 12, 2001... 2001 NOV 12 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in Germany have improved the effectiveness of an HIV vaccine based on viral genetic material. "We have analyzed the influence of codon usage...

Novel Reverse Transcriptase Inhibitor Suitable For Further Study.(Brief Article)
November 12, 2001... 2001 NOV 12 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - The novel HIV drug currently dubbed GW420867X warrants further study in human clinical trials, according to researchers in North Carolina. K.H. Moore and...

Center To Study 'Spiritual Palliation' For AIDS End-Of-Life Patients.(Brief Article)
November 12, 2001... 2001 NOV 12 - (NewsRx.com & NewsRx.net) -- The Yale-Griffin Prevention Research Center, part of the Yale School of Medicine, has been awarded a two-year, nearly $200,000 grant from the National Institutes of Health to investigate the benefits...

Longer Treatment Recommended For Coinfected Patients.(Brief Article)
November 12, 2001... 2001 NOV 12 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Patients coinfected with tuberculosis and HIV have a heightened risk of tuberculosis relapse, researchers in the United States warn. "The optimal duration...

Smart Carriers Improve Drugs' Effectiveness.(Brief Article)
November 12, 2001... 2001 NOV 12 - (NewsRx.com & NewsRx.net) -- An oral or injected "smart" drug carrier that seeks out targeted diseased cells in the body and a tiny gel "medicine cabinet" injected under the skin to supply drugs as needed on a weekly, monthly or...

CXCR4 Disturbance May Impact Stem Cell Activity.(Brief Article)
November 12, 2001... 2001 NOV 12 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - The CXCR4 chemokine axis influences the activity of hematopoietic progenitor cells, and disturbance of this axis during HIV infection may affect blood cell...

Spirodiketopiperazine Derivatives Block R5 HIV Infection.(Brief Article)
November 12, 2001... 2001 NOV 12 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Low-molecular-weight spirodiketopiperazine derivatives can prevent cell entry by R5 strains of HIV, according to researchers in Japan and the United States....

VaxGen Awarded Second NIH Grant To Develop AIDS Vaccine.(Brief Article)
November 12, 2001... 2001 NOV 12 - (NewsRx.com & NewsRx.net) -- VaxGen Inc. has been awarded the second part of a $1.1 million grant from the National Institutes of Health (NIH) to continue the development of a vaccine designed to prevent infection by HIV subtype...

NIH Uses Bioject's Needle-Free Injection System For DNA AIDS Vaccine Study.(Brief Article)
November 12, 2001... 2001 NOV 12 - (NewsRx.com & NewsRx.net) -- The Biojector 2000 (B-2000) has been chosen by the Dale and Betty Bumpers Vaccine Research Center (VRC) as the delivery device for its first AIDS vaccine in human clinical testing. The B-2000 was...

PowderJect Awarded $1 Million Grant For Development Of HIV DNA Vaccine.(Brief Article)
November 12, 2001... 2001 NOV 12 - (NewsRx.com & NewsRx.net) -- PowderJect Pharmaceuticals Plc (PJP), a specialty vaccines company, and its wholly owned subsidiary PowderJect Vaccines Inc., have, in association with the University of Pittsburgh, been awarded $1...

Stress Accelerates AIDS Progression And Undermines Anti-HIV Drugs.(Brief Article)
November 12, 2001... 2001 NOV 12 - (NewsRx.com & NewsRx.net) -- New University of California, Los Angeles AIDS Institute research reveals that stress enables HIV to spread more quickly in infected persons and prevents antiretroviral drugs from restoring immune...

Bio-Terrorism.Info Database and Weekly Report Launch Powered by NewsRx Artificial Intelligence Technology.(Brief Article)
November 12, 2001... 2001 NOV 12 - (NewsRx.com & NewsRx.net) -- NewsRx has leveraged its technology platform to create Bio-Terrorism.Info, a new database and weekly report. NewsRx is the leading provider of life science databases and daily and weekly health news....

VaxGen To Manufacture AIDS Vaccine In South Korea.(Brief Article)
November 12, 2001... 2001 NOV 12 - (NewsRx.com & NewsRx.net) -- VaxGen Inc. (VXGN) and the city of Incheon, South Korea, have signed an agreement that provides VaxGen land on which to construct a facility to manufacture the company's AIDS vaccine. This agreement...

FDA Approves Tenofovir Disoproxil Fumarate For Treatment Of HIV Infection.(Brief Article)
November 12, 2001... 2001 NOV 12 - (NewsRx.com & NewsRx.net) -- The U.S. Food and Drug Administration (FDA) has approved Viread (tenofovir disoproxil fumarate), a new antiviral drug indicated for treatment of HIV-1 infection in combination with other antiretroviral...

Intermediate Viral Structures May Be Target.(Brief Article)
November 12, 2001... 2001 NOV 12 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Viral structures formed during HIV coreceptor interactions can be targeted by potential HIV vaccines, researchers in the United States report. "Human...

Cylex Inc. Signs Agreement With Dynal Biotech For Dynabeads Technology.(Brief Article)
November 12, 2001... 2001 NOV 12 - (NewsRx.com & NewsRx.net) -- Cylex Inc., a privately held company, has entered into an agreement with Dynal Biotech ASA of Oslo, Norway for Dynal Biotech to supply Dynabeads to Cylex for use in conjunction with Cylex's patented In...

DHEA Replacement Therapy Effective.(Brief Article)
November 19, 2001... 2001 NOV 19 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Treatment with the adrenal hormone DHEA can be beneficial for patients in advanced stages of HIV infection, researchers in France report. "Plasma levels...

P-glycoprotein May Prevent Microglia Exposure To Therapeutic Drugs.(Brief Article)
November 19, 2001... 2001 NOV 19 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - P-glycoprotein appears to block HIV protease inhibitors from reaching viral targets in the brain, according to researchers in Canada. "In the central...

Prednisone Ineffective Against Nevirapine-Induced Rash.(Brief Article)
November 19, 2001... 2001 NOV 19 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Prednisone should not be used to treat rashes induced by the HIV reverse transcriptase inhibitor nevirapine, researchers in Spain warn. "Rash is the most...

Viral Protein Alterations Have Similar Impact On HIV, SHIV Specific Antibodies.(Brief Article)
November 19, 2001... 2001 NOV 19 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in New York City have presented evidence in favor of the controversial use of simian/human immunodeficiency virus (SHIV)-based models for HIV...

Herpesvirus 6 Prevents HIV Variant From Spreading In Humans.(Brief Article)
November 19, 2001... 2001 NOV 19 - (NewsRx.com & NewsRx.net) -- Human herpesvirus 6 (HHV-6), a common virus that is apparently harmless in adults, appears to prevent a form of the AIDS virus from reproducing in laboratory cultures of human tissue, according to a...

Coinfection Does Not Appear To Augment TB Infectivity.(Brief Article)
November 19, 2001... 2001 NOV 19 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Tuberculosis from patients coinfected with HIV is not usually more infective than tuberculosis from HIV negative patients, according to researchers in Italy....

New Details About Epitope Targeted By Potent Monoclonal Antibody.(Brief Article)
November 19, 2001... 2001 NOV 19 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in the United States and Europe say that they have shed new light on a potential HIV vaccine target. In a multi-institutional study, Carol E....

Improved Dosing Formulations For Investigational Drug In Development.(Brief Article)
November 19, 2001... 2001 NOV 19 - (NewsRx.com & NewsRx.net) -- Progenics Pharmaceuticals, Inc., announced the initiation of a collaboration with Formatech, Inc., Andover, Massachusetts, to develop improved product formulations for PRO 542, an investigational drug...

FDA Approves Investigational Device Exemption For Efoora HIV Rapid Test.(Brief Article)
November 19, 2001... 2001 NOV 19 - (NewsRx.com & NewsRx.net) -- The Center for Biologics Evaluation and Research (CBER) of the U.S. Food and Drug Administration (FDA) has granted an Investigational Device Exemption (IDE) for Efoora, Inc.'s, HIV Rapid Test. The...

Article Describes New "Golden Age" Of Antiviral Drugs And Vaccines.(Brief Article)
November 19, 2001... 2001 NOV 19 - (NewsRx.com & NewsRx.net) -- Advances in the study of viral genomes has laid the foundation for rapid progress in the development of new antiviral vaccines and drugs. "The 1950s were the golden age of antibiotics to treat...

Visible Genetics Genotyping Kit To Be Used In GlaxoSmithKline Trial.(Brief Article)
November 19, 2001... 2001 NOV 19 - (NewsRx.com & NewsRx.net) -- Visible Genetics, Inc.'s, Trugene HIV-1 Genotyping Kit will be used to provide genotype information on all patients enrolled in a large-scale, Phase III clinical trial sponsored by GlaxoSmithKline...

Treatment Strategy Doubles Efficacy In HIV Coinfected Patients.(Brief Article)
November 19, 2001... 2001 NOV 19 - (NewsRx.com & NewsRx.net) -- Daily administration of interferon alfa-2b in combination with ribavirin for the treatment of the hepatitis C virus (HCV) is more than twice as effective as the standard treatment regimen (three...

Phase I Clinical Trial Of SL11047 Commence In AIDS Patients.(Brief Article)
November 19, 2001... 2001 NOV 19 - (NewsRx.com & NewsRx.net) -- SLIL Biomedical Corp. announced that the U.S. Food and Drug Administration (FDA) has completed its review of the Investigational New Drug application (IND) for SLIL's candidate drug, SL11047. Phase I...

Success Of HIV Therapy May Discourage Safe Sex.(Brief Article)
November 19, 2001... 2001 NOV 19 - (NewsRx.com & NewsRx.net) -- A recent survey reveals that some gay and bisexual men believe AIDS therapy reduces the risk of transmitting the virus to sexual partners and that this belief is associated with greater likelihood of...