AIDS Weekly articles from May 2004

AIDS Weekly archives from May 2004

E152 amino acid region of HIV integrase characterized.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- The region of HIV integrase carrying the E152 amino acid has been characterized. "HIV-1 integrase (IN) catalyzes the integration of the proviral DNA into the cellular genome," scientists in France...

Muslim areas in Africa have lower rates of HIV infection.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Islam may be linked to reduced rates of HIV infection in Africa. According to researchers in the United States, "[r]eligious constraints on sexuality may have consequences for the transmission of...

Recombinant AAV-2 useful as anti-HIV RNAi vector.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Recombinant AAV-2 is suitable for use as an anti-HIV RNAi vector. According to recent research from Rhode Island, the "cellular introduction of short, interfering RNA leads to sequence-specific...

Early IL-2 treatment increases CD4 cell count in HIV patients.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Exogenous IL-2 therapy can augment CD4 cell counts in HIV patients undergoing antiretroviral treatment. "Early treatment intervention during human immunodeficiency virus (HIV) infection is a...

In utero AZT exposure has little or no impact on neurodevelopment.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Exposure to the antiretroviral agent azidothymidine (AZT) in utero does not have a significant impact on neurodevelopment. AZT is "administered to pregnant women with HIV to prevent the spread of...

Antibodies that recognize HIV coreceptor-binding site on gp120 studied.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Scientists describe the structural basis of tyrosine sulfation and V[subscript]H-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120 in a recent issue of the...

Attenuated SIV vaccine provides early protection against viral infection.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Vaccination with attenuated simian immunodeficiency virus provided early protection against pathogenic viral infection at a mucosal challenge site. "Atraumatic application of attenuated...

Epitope mimic for human HIV-neutralizing antibody 2G12 synthesized.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Scientists have synthesized a template-assembled oligomannose cluster as an epitope mimic for human HIV-neutralizing antibody 2G12. According to published research from the United States, "The...

HIV synthetic peptide-cocktail prevents SHIV transmission.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- An HIV synthetic peptide-cocktail prevented SHIV transmission in rhesus macaques. "An effective vaccine against human immunodeficiency virus (HIV) should not only protect from infection and...

Low-dose mucosal SIV challenge has same kinetics as high-dose challenge.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Repeated low-dose mucosal simian immunodeficiency virus SIVmac239 challenge results in the same viral and immunological kinetics as high-dose challenge. According to published research from the...

Nasal vaccine controls SHIV viremia and disease progression in primates.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- IL-2-augmented DNA-modified vaccinia virus Ankara nasal vaccination controlled simian/human immunodeficiency virus viremia and disease progression in nonhuman primates. According to recent research...

CLEAR II registry launched.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Enzon Pharmaceuticals, Inc., (ENZN) announced a major new initiative to build upon the value of its CLEAR (Collaborative Exchange of Antifungal Research) patient registry with the launch of CLEAR II....

Agreement signed for HIV molecular diagnostics.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- EraGen Biosciences, a rapidly growing life science company driving a new era in genetic diagnostics and drug discovery, announced they have entered into a collaboration agreement with Emory University...

VScan HIV Rapid Test Kits placed in dispensaries in Southeast Asia.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Medical Services International, Inc., (MSITF) announced that its VScan HIV 1&2 Rapid Test Kits will now be carried in drugstores in Hong Kong. The Hong Kong distributor working with Medical Services...

QSAR analysis on anti-HIV HEPT analogues described.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- A QSAR analysis of putative antiretroviral HEPT analogues has been described. According to published research from India, a "Quantitative Structure-Activity Relationship (QSAR) study has been...

HIV/gammaretrovirus-based STAR vector packaging system evaluated.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- A novel gene therapy vector system based on gammaretrovirus-psuedotyped HIV has been evaluated. Scientists in England "recently described a novel, stable human immunodeficiency virus type 1 (HIV-1)...

Clues discovered to Trojan horse gene in HIV infection.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Researchers are probing details of how HIV commandeers genes in infected cells to disguise itself from the immune system. The researchers, from The Children's Hospital of Philadelphia, have...

Board recommends dosing of final two patients in VRX496 trial.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- VIRxSYS Corporation announced that the independent Data Safety Monitoring Board (DSMB) unanimously recommended that the remaining two patients in the company's phase I trial be dosed using VRX496...

Early anti-EBV cytotoxic immune response impaired in HIV patients.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- The early cytotoxic response to Epstein-Barr virus (EBV) is impaired in HIV patients. According to recent research from France, "[i]mmunodeficiency related to HIV may increase the incidence of...

Minnesota's new HIV cases drop to 20-year low.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Minnesota reported only 266 new HIV cases last year, the lowest number of new cases in 20 years, the state Health Department said. The department reported the 13% decline in the virus that causes...

NCI awards contract for studies in cancer, AIDS, and AIDS-related illnesses.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Gene Logic, Inc., (GLGC) announced that it has entered into a multiyear agreement with the National Cancer Institute (NCI), division of cancer treatment and diagnosis, to provide preclinical safety and...

Senators detail global report on children and HIV/AIDS.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Members of Congress, business leaders, and leaders in the women's and children's rights communities gathered on Capitol Hill at a luncheon to launch a landmark report on the impact of HIV/AIDS on...

Study evaluating Resurgex in immunocompromised patients completed.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Millennium Biotechnologies, Inc., a wholly owned subsidiary of Millennium Biotechnologies Group, Inc., (MBTG) announced the completion of its 6-month clinical pilot study "Evaluating the Effects of...

Study shows no significant interactions in Invirase/Ritonavir with Tenofovir.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Roche announced results from a study demonstrating that the new boosted dosing regimen for its protease inhibitor Invirase (saquinavir 1000 mg with ritonavir 100 mg twice-daily) has no significant...

Rare case of thrombotic thrombocytopenic purpura described.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- A rare case of thrombotic thrombocytopenic purpura underlying thrombocytopenia in a hemophiliac HIV patient has been reported. "Thrombocytopenia is a common complication in human immunodeficiency...

HAART-induced recovery of HIV-specific immunity described.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- The recovery of HIV-specific immune activity in HAART-treated patients has been elucidated. According to recent research from Canada, the "extent to which highly active antiretroviral therapy...

Astrocyte-induced matrix remodeling may mediate HIV-related neurodegeneration.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Astrocyte-induced matrix remodeling may help mediate HIV-related neurodegeneration. According to neurovirologists in France, "[c]hanges in the fine balance between matrix metalloproteinases and...

Pneumocystis carinii p55 variants identified.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Polymorphism in the Pneumocystis carinii p55 antigen has been described. In a recent study from Maryland, "[v]ariants of the p55 gene in rat-derived" P. carinii were identified, and "its...

Dapsone-induced hypersensitivity pneumonitis can mimic PCP.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Hypersensitivity pneumonitis triggered by dapsone exposure can emulate PCP in HIV/AIDS patients. "Interstitial pneumonitis, often related to infectious etiologies, occurs commonly in HIV-infected...

Essential eukaryotic core identified from P. carinii.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Genetic data from Pneumocystis carinii has been used to elucidate the essential eukaryotic core. According to researchers in the United States, P. carinii, an "AIDS-related fungal pathogen," is...

Visceral leishmaniasis relapse common during ineffective HAART.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Relapse of visceral leishmaniasis (VL) is common in HIV patients with a weak response to HAART. According to recent research from Spain, there are "contradictory data about whether highly active...

HIV Tat binds directly to NFkappaB enhancer.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- HIV Tat binds directly to the NFkappaB enhancer. "HIV-1 Tat protein reprograms cellular gene expression of infected as well as uninfected cells apart from its primary function of transactivating...

China offers free AIDS tests and treatment for the poor.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- China on April 14, 2004, began offering free AIDS tests to anyone who wants one and free treatment for infected people who can't afford it, amid growing official urgency about stopping the spread of the...

Antiretroviral therapy does not prevent contingent negative variation.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Antiretroviral treatment does not prevent contingent negative variation abnormalities in HIV patients. In a recent study from California, the "contingent negative variation, an event-related...

Cessation of CMV retinitis therapy has no long-term sequelae for HIV patients.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Cessation of successful CMV retinitis therapy has no long-term sequelae for HIV patients. "Potent antiretroviral therapy stimulates robust and durable immune reconstitution among profoundly...

Dose escalation unnecessary in patients switching to nevirapine from efavirenz.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Dose escalation in not necessary when switching HIV patients to nevirapine from efavirenz treatment. "Efavirenz induces the metabolism of co-administered drugs through the induction of CYP 3A4,"...

Indinavir superior to ritonavir and saquinavir in triple therapies.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Indinavir is superior to ritonavir and saquinavir as a component of triple antiretroviral regimens. According to a recent study from Spain, the "introduction of the so-called highly active...

Indinavir/ritonavir/efavirenz regimen should benefit treatment-naive patients.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Treatment-naive HIV patients should respond well to a regimen of indinavir and ritonavir at standard dose levels with efavirenz. According to published research from the Netherlands, a...

Pre-HAART IL-7 levels linked to long-term CD4 cell count.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Interleukin (IL)-7 levels prior to HAART initiation are correlated with long-term CD4 cell recovery. "Highly active antiretroviral therapy (HAART) in HIV patients generally increases the CD4 cell...

Surgery can benefit patients with antiretroviral-induced "buffalo hump".
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Surgical intervention is feasible for treatment-induced "buffalo humps" in HIV patients. "Fat redistribution disorders are common complications of antiretroviral therapy," explained C. Gervasoni...

Iowa City man convicted fourth time for transmitting HIV.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- An Iowa County jury deliberated for less than an hour before finding a man guilty of criminally transmitting HIV, the virus that causes AIDS. The April 13, 2004, verdict marks the fourth time this...

Arkansas plans waiting list for HIV drugs.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Arkansas plans to reinstate a waiting list for HIV patients who need help paying for medications. Through a federal grant, the state can only assist 460 patients and demand is expected to surpass...

Pharmaceutical company to make AIDS drug widely available.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- A year after launching the first drug in a new class of AIDS medications, Hoffmann-La Roche Inc. says it has overcome shortages of its hard-to-manufacture Fuzeon and is making it widely available. ...

Mycobacteremia among HIV patients in Sao Paulo examined.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- The rate of mycobacterial infections - including tuberculosis - among HIV patients in Sao Paulo has been characterized. "From July 1995 to August 1998, mycobacterial blood cultures were obtained...

Antimicrobial technology granted EPA registration.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- A pioneering antimicrobial technology from Engelhard Corporation (EC) has been granted registration by the U.S. Environmental Protection Agency (EPA) for use against tuberculosis, HIV and many other...

Preclinical study points to development of glucosylceramide.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Enzo Biochem, Inc., (ENZ) scientists recently presented results of a preclinical study in an animal model system evaluating one of the company's new immunomodulatory agents, glucosylceramide (GC), as a...

Lytic KSHV infection inhibits host gene expression.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Surprisingly, lytic KSHV infection has been found to suppress gene expression by the host. According to researchers in the United States, the "stimulation of host gene expression by lytic gene...

Researchers identify virus gene involved in tumor cell growth, spread.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- In studying a virus that causes the skin cancer Kaposi sarcoma, University of North Carolina (UNC) at Chapel Hill scientists have identified a viral gene that switches on cellular genes involved in...

Court won't hear McDonald's AIDS discrimination case.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- The Ohio Supreme Court on April 14, 2004, refused to hear an appeal of a ruling that overturned a $5 million verdict won by a former McDonald's restaurant manager who claimed he was discriminated...

Pneumococcal vaccine not useful in HIV patients responding to HAART.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- The 23-valent pneumococcal vaccine does not offer additional protection against pneumonia in HIV-infected patients who have an immunological response to highly active antiretroviral therapy (HAART). ...

World to be polio-free by next year, but losing AIDS war.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- The world is likely to be polio-free next year, but the war against AIDS is being lost, the U.S. health secretary says. "We're on the precipice of accomplishing it," Tommy Thompson said of...

Program aims to help HIV+ mothers reduce self- and childcare stresses.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- MOMS (Making Our Mothers Stronger), a University of Alabama at Birmingham (UAB) School of Public Health program, aims to help HIV positive moms reduce the stresses of caring for themselves and their...

HIV-positive U.S. military personnel accidentally vaccinated against smallpox.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Ten U.S. military personnel were discovered to be HIV-positive after being vaccinated against smallpox, but did not experience any harmful effects from the vaccination, according to a new study. In...

Broth microdilution with 7H9 broth suitable as TB drug resistance test.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Broth microdilution using 7H9 provides an accurate measure of Mycobacterium tuberculosis drug resistance. In a recent study, scientists in Turkey "evaluated the broth microdilution method (BMM) for...

Antibodies and CD8+ T cells contribute to immunity to adenovirus vectors.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Neutralizing antibodies and CD8+ T lymphocytes both contribute to immunity to adenovirus serotype 5 vaccine vectors. According to a study from the Netherlands and the United States, "The high...

HIV employs a sugar shield to evade host defenses.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- In humans, the AIDS virus HIV manifests extreme genetic variability. It is particularly virulent, probably because its introduction into populations is recent. The virus has a potential for rapid...

TMP-SMZ therapy does not select for S. aureus small colony variants.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Surprisingly, TMP-SMZ treatment does not increase the risk of Staphylococcus aureus small colony variant (SCV) infection in HIV patients. Emergence of S. aureus SCVs "has been associated with...

Naive, infection-resistant lymphocytes dominate immune recovery in children.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Immune recovery in pediatric HIV patients primarily involves naive, infection-resistant lymphocytes. In a study from the United States, the "associations between human immunodeficiency virus type...

Actin filaments play role in intracellular transport of nascent HIV-1 proteins.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Actin filaments play a crucial role in the intracellular transport of nascent HIV-1 proteins. According to published research from Japan, to "investigate the role of actin filaments (F-actin) for...

Acute HIV infection linked to stable or reduced HBV loads.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Surprisingly, acute HIV infection appears to reduce HBV loads in hepatitis B patients. Scientists in Baltimore "hypothesized that acute infection with human immunodeficiency virus (HIV) would...

Protective effect of circumcision against HIV has biological explanation.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Biological factors underlie the protective effect of circumcision against HIV infection. "Circumcised men have a lower risk of HIV-1 infection than uncircumcised men," scientists in the United...

Crack cocaine use reduces antiviral therapy use in women with HIV.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Crack cocaine use decreases adherence to antiretroviral treatment among HIV-infected Black women. "Since the appearance of crack cocaine in the 1980s, unprecedented numbers of women have become...

Fuzeon to be widely available in U.S. pharmacies.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Roche and Trimeris (TRMS) announced that Fuzeon (enfuvirtide), the first and only fusion inhibitor available for the treatment of HIV, will be available through retail and specialty pharmacies across...

Neutralizing HIV epitopes available in newly-infected patients.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Neutralizing HIV epitopes are available in newly-infected patients. According to published research from the United States, England, and Zambia, "Heterosexual transmission accounts for the majority...

Vaccine allows for infection control in macaques exposed to SHIV.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Priming B cell-mediated anti-HIV envelope responses by vaccination allows for the long-term control of infection in macaques exposed to a R5-tropic SHIV. "The potential of vaccine-elicited anti-HIV...

Features of HIV- and hepatitis C-related APS described.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- The symptoms associated with APS in HIV and hepatitis C patients have been characterized. In a recent study, researchers in Spain "analyzed the spectrum of clinical features related to...

R&D agreement signed with CDC for rapid HIV incidence test.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Calypte Biomedical Corporation (CYPT) has executed a CRADA - a Cooperative Research and Development Agreement - with the U.S. Centers for Disease Control and Prevention (CDC) for the development of a...

HIV test kits recently tested.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Medical Services International, Inc., (MSITF) has completed a major test of its HIV 1&2 test kits in the United States. The samples used in the test were obtained geographically from all over the...

Home Access FDA-approved at-home tests to be distributed internationally.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Vencor International, Inc., (VNCO) is expanding its newly developed relationship with Home Access Health Corporation by entering into a Memorandum of Understanding to develop international channels of...

Peptide-protein microarrays enable serodetection of multple pathogens.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- A peptide-protein immunoassay enables detection of multiple pathogens in serum. Researchers in France developed "novel peptide-protein microarrays, which were fabricated using semicarbazide glass...

Semicarbazide and amine slides for peptide-protein microarray assay compared.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- The utility of semicarbazide and amine slides have been compared for a novel peptide-protein assay. In the journal Bioconjugate Chemistry, researchers in France described "the preparation of...

HIV integrase pharmacophore model developed.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- A novel HIV-1 integrase (HIV-IN) pharmacophore model has been developed and validated. According to recent research from the United States, this "three-dimensional pharmacophore model" was...

Thiophene-containing nelfinavir analog synthesized.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- The first thiophene-containing analog of the antiretroviral agent nelfinavir has been synthesized. C. Bonini and colleagues at the University of Basilicata in Potenza, Italy developed a...

Biopharma company offers up to 4,000,000 shares of common stock.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- GenVec, Inc., (GNVC) announced that it is offering, through Stonegate Securities, Inc., as placement agent, to sell up to 4,000,000 shares of its common stock for $3.15 per share, prior to commissions,...

Diagnostics company closes final round of debenture financing.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- MedMira, Inc., (MIR) announced that it has closed an additional $588,000 from three private investors of the debenture financing, announced on February 17, 2004. Included in this round is $40,000...

Nutraceutical company records a 33% increase in unit sales for fourth quarter.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Millennium Biotechnologies, Inc., a wholly owned subsidiary of Millennium Biotechnologies Group, Inc., (MBTG), announced a 33% increase in unit sales over the preceding quarter. Unit sales, in the...

FDA grants clearance for HIV viral entry inhibitor to begin phase Ib/IIa trial.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Adventrx Pharmaceuticals, Inc., (AVRX) announced that the Investigational New Drug Application (IND) for its HIV-1 entry inhibitor, BlockAide/CR, received U.S. Food & Drug Administration (FDA)...

Effect of HIV infection on NK cell inhibitory receptors clarified.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- The effect of HIV infection on NK cell receptor expression has been elucidated. In a recent study, researchers in the United States "examined the cell-surface expression of chemokine and natural...

FDA grants traditional approval status to Ziagen.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- GlaxoSmithKline (GSK) announced that the U.S. Food and Drug Administration (FDA) has granted traditional approval status to Ziagen (abacavir sulfate) (ABC) for the treatment of HIV infection in...

Genital ulcer disease linked to heightened HIV loads.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Genital ulcer disease is associated with elevated HIV viremia. In a study from the United States, "[h]uman immunodeficiency virus (HIV) type 1 RNA loads were determined for 256 subjects with early...

Preclinical data support continued development of IR103 HIV drug candidate.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- The Immune Response Corporation (IMNR) announced that preclinical data for its newest product candidate, IR103, were presented at the Keystone Symposium on HIV Vaccine Development held in Whistler,...

Subtype-specific transcriptional promoters determine replication rate.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- The distinct long terminal repeats (LTRs) of the various HIV subtypes determines their replication rates in different host cells. In a study from the Netherlands, the LTR "transcriptional...

HIV/AIDS monitoring research could reduce costs for African nations.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- The cost of HIV/AIDS monitoring has long been a barrier to successful treatment in Africa. Now, research funded by Secure the Future, an HIV/AIDS philanthropic initiative funded by the...

Novel molecular assay quantifies HIV-2 viremia.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- A novel molecular assay enables quantification of HIV-2 viremia. "Similar to HIV-1, the viral load in HIV-2 is a marker of the evolution of infection and the success of therapy," virologists in...