AIDS Weekly articles from May 2003

AIDS Weekly archives from May 2003

Peptide constraints enhance anti-gp41 immunogenicity.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in the United States have found a way to improve the efficacy of an anti-HIV monoclonal antibody that could serve as the basis for an effective...

TREC analysis shows little thymic damage during adolescence.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- Thymic damage during adolescence is surprisingly limited in pediatric HIV patients. "Circular DNA molecules known as T-cell receptor rearrangement excision circles (TREC) arise during T-cell...

Techniques for optimizing macaque T-cell yields identified.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- A series of techniques have been identified for maximizing T-cell yields from rhesus macaques used in HIV treatment research. "The rhesus macaque model is a useful experimental system to evaluate...

Risk of vision loss is high in AIDS patients.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- The prevalence of visual impairment for patients who have acquired immunodeficiency syndrome (AIDS) and are diagnosed with cytomegalovirus (CMV) retinitis is high, but varies with demographic...

Standard viral genotyping systems suitable for use with non-subtype B strains.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- Standard HIV genotyping systems are suitable for use with non-B viral subtypes. Because of the rising frequency of subtype A and other strains in North America, "genotypic assays must be capable of...

Adenovirus vector shows promise.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - A novel vector shows promise for use in HIV and other vaccines, researchers in Maryland say. "A strategy to circumvent immune responses to adenovirus (Ad)...

CDC tries new strategies in HIV battle.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- Saying AIDS prevention efforts have "stalled," the U.S. government announced a new strategy it hopes will sharply increase routine testing of people at risk for the disease. The U.S. Centers for...

Stampidine first effective agent against FIV.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- Scientists from Parker Hughes Cancer Center report that stampidine is the first single agent to be safe and effective in treating cats chronically infected with feline immunodeficiency virus, or FIV....

FDA clears Cobas Amplicor HIV-1 Monitor Test.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- Roche announced that it has received clearance from the U.S. Food and Drug Administration (FDA) for the Cobas Amplicor HIV-1 Monitor Test (version 1.5), an enhanced version of Roche's polymerase chain...

Rapid HIV test earns regulatory approval for China.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- MedMira, Inc., (MIR) announced that it has received approval from the State Drug Administration (SDA) of the People's Republic of China for its MiraWell Rapid HIV Test. According to Stephen Sham,...

Study: Half of HIV patients who died at Parkland not on antiviral.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- Nearly half of HIV-infected patients who died at Parkland Hospital from 1999 to 2000 were not taking antiviral medications, a finding that surprised researchers at the University of Texas Southwestern...

Virucort may slow development of HIV.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- Cortisol Medical Research has announced a new drug that may slow the development of HIV. Virucort is a drug developed by Dr. Alfred T. Sapse that has the potential of slowing down or even preventing...

Modified p24 antigen detection assay effective.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- A modified p24 antigen detection test may be useful for disease monitoring in developing areas. Researchers in Thailand "modified a p24 antigen enzyme-linked immunosorbent assay as a method for...

Novel immunochromatographic assay fast, accurate.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- A novel HIV screen provides fast and accurate results. According to recent research published in the journal Clinical and Diagnostic Laboratory Immunology, "a new immunochromatographic rapid test...

Subtype frequency varies in different regions of Venezuela.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- HIV subtype frequency varies in different regions of Venezuela. In a recent study, investigators in Brazil "assessed HIV-1 variability in two distinct areas of Venezuela (the capital Caracas and...

CX3CR1 mutation linked to rapid disease progression.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- A polymorphism in the CX3CR1 gene is associated with rapid disease progression in HIV patients. A group of researchers in France had previously noted that "patients homozygous for a specific...

Six-helix bundle may protect fusion pores.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- Bundle formation by HIV proteins plays a key role in the fusion process. "Fusion proteins of many viruses, including HIV-1 envelope protein (Env), fold into six-helix bundle structures," researchers...

Harm reduction programs reduce drug users' risky behavior.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- Comprehensive harm reduction programs reduce deleterious behavior by HIV-infected drug users. A recent study from Yale University "randomized 90 HIV-seropositive, methadone-maintained injection...

Orphan crisis in sub-Saharan Africa blamed on AIDS prevalence.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- The orphan crisis emerging in sub-Saharan Africa has been blamed on the prevalence of AIDS in that region. "This study uses recent Demographic and Health Survey (DHS) data to examine levels,...

Novel assay provides fully automatic viremia measurements.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- A novel assay provides fully automatic measurements of HIV viremia. In a recent study from Austria, "the ultrasensitive COBAS AMPLICOR HIV-1 Monitor test was complemented with automated RNA...

High interlaboratory variability seen in drug level measurements.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- Interlaboratory discrepancies in measurements of antiretroviral medications in plasma is disturbingly high. According to a recent study from the Netherlands, "since 1999 an ongoing international...

Indinavir suppresses glycogen synthesis in HepG2 hepatoma cells.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- The HIV protease inhibitor indinavir suppresses glycogen synthesis in HepG2 hepatoma cells. Protease inhibitor therapy "is associated with insulin resistance," explained researchers in Germany who...

St. John's wort suppresses UV-induced HIV gene expression.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- St. John's wort, a popular herbal antidepressant, suppresses HIV gene expression triggered by ultraviolet (UV) light. UV radiation "is a potent activator" of HIV expression in HeLa cells "with...

Test errors do not explain viremia "blips" in patients on combination therapy.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- Mechanical errors do not account for transient HIV viremia increases often seen during antiretroviral treatment. HIV patients "treated with combination antiretroviral therapy frequently have the...

First AIDS vaccine tested in Africa generates low immune response.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - A preventive AIDS vaccine containing HIV-1 clade B (env and gag-pro) antigens delivered by a canarypox vector elicited a weak but detectable immune...

HIV Tat protein useful for angiotensin II study.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- The HIV transactivation (Tat) protein can aid research on angiotensin II function. "Despite advances in transgenic and gene transfer technologies, in vivo structure-function studies of the...

Drug discovery, development research grant program announced.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- GlaxoSmithKline (GSK) will award $500,000 in grants for innovative HIV/AIDS drug research in recognition of the need to produce new alternatives and hope in the fight against the HIV/AIDS pandemic. ...

HHV8 and HIV Tat interaction linked to pathogenesis.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- An interaction between human herpesvirus 8 (HHV8) and the HIV Tat protein plays a role in Kaposi sarcoma development. "AIDS-associated Kaposi's sarcoma (AKS) is particularly aggressive, and it is...

Discovery of proteins suggests possible new therapeutic targets.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- Dr. Wesley Sundquist, professor of biochemistry at the University of Utah, presented at the Experimental Biology 2003 meeting in San Diego on his work in elucidating how HIV is manufactured and...

Ribosomal DNA useful for nontuberculous mycobacteria identification.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- Ribosomal DNA sequencing is an effective method for identifying nontuberculous strains of mycobacteria. "The clinical profile of nontuberculous mycobacteria (NTM) has been raised by the human...

Pneumocystis carinii load linked to alveolar macrophage count.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- High pathogen levels in pneumocystis patients are associated with low levels of some pulmonary immune cells. "Changes in the number of alveolar macrophages were correlated with organism burden...

Tobacco use increases pulmonary infection, treatment failure risk.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- Tobacco use increases the risk of pulmonary infection and treatment failure in HIV patients. "The increased risk of developing lung diseases in cigarette smokers has been well recognized,"...

Drug-resistant viral genotypes common in neonates.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- Drug-resistant HIV genotypes are as common in infected newborns as in adult patients, even in the absence of perinatal drug exposure. According to researchers in the United States, "a...

Efficacy results of DB289 in pneumonia trial released.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- Immtech International, Inc., (IMMT) announced the completion of a pilot phase IIa human clinical trial of its oral drug DB289 to treat AIDS patients with Pneumocystis carinii pneumonia (PCP), a form of...

Report discusses lessons learned from China crisis.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- A new report discusses how China can learn from mistakes made in its handling of the SARS crisis - especially in relation to the increasing prevalence of HIV/AIDS. "China's lack of openness about...

Treatment restores normal neutrophil function in HIV-negative patients.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- Anti-tuberculosis therapy restores normal neutrophil function to HIV-negative patients. Researchers in Argentina "investigated whether the respiratory burst (RB) of polymorphonuclear neutrophils...

RANTES and CpG oligodeoxynucleotides effective adjuvants in SIV vaccine.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - RANTES and CpG oligodeoxynucleotides (ODN) functioned as adequate substitutes for the cholera toxin (CT) as potent adjuvants for a simian...

HIV vaccine candidate taken by into phase I trial in U.S., Africa.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- Epimmune, Inc., (EPMN) announced that the National Institute of Allergy and Infectious Diseases, a component of the U.S. National Institutes of Health (NIH), holds an active Investigational New Drug...

Researchers find method to study hidden HIV reservoirs.
May 5, 2003... 2003 MAY 5 - (NewsRx.com & NewsRx.net) -- Scientists are now one step closer to understanding how HIV hides in cells and rears its ugly head once patients stop taking combination drug therapy, which can suppress viral loads to undetectable...

Azido-containing aryl beta-diketo acid HIV-1 integrase inhibitors described.
May 12, 2003... 2003 MAY 12 - (NewsRx.com & NewsRx.net) -- Researchers at the National Istitutes of Health report the first use of azido-containing aryl beta-diketo acid HIV-1 integrase inhibitors. "Aryl beta-diketo acids (ADK) comprise a general class of...

Human immunodeficiency virus may use transcytosis to cross genital mucosa.
May 12, 2003... 2003 MAY 12 - (NewsRx.com & NewsRx.net) -- The human immunodeficiency virus may use transcytosis across a tight monolayer of polarized human endometrial cells under pro-inflammatory conditions. According to recent research from France,...

Caspofungin successfully treats resistant oropharyngeal candidiasis.
May 12, 2003... 2003 MAY 12 - (NewsRx.com & NewsRx.net) -- Researchers in Switzerland report caspofungin successfully treats resistant oropharyngeal candidiasis. "A patient with AIDS developed oropharyngeal candidiasis. Candida albicans and C. glabrata...

Pneumonia rate unchanged after interruption of prophylaxis treatment.
May 12, 2003... 2003 MAY 12 - (NewsRx.com & NewsRx.net) -- The increase in rates of community-acquired pneumonia among HIV-infected patients was not statistically significant after prophylaxis treatment was stopped, researchers in Bern report. According...

No correlation found between HIV status and malaria-specific parameters.
May 12, 2003... 2003 MAY 12 - (NewsRx.com & NewsRx.net) -- According to researchers in the United States, no correlation was found between HIV status and malaria-specific parameters among a small group of patients in Kinshasa. "Co-infection of human...

Group applauds new CDC guidelines on HIV/AIDS prevention.
May 12, 2003... 2003 MAY 12 - (NewsRx.com & NewsRx.net) -- The Medical Institute for Sexual Health has hailed the U.S. Centers for Disease Control and Prevention's new guidelines on HIV/AIDS prevention. The organization released this statement by Joe S....

Official: Up to 1.5 million Russians estimated to have AIDS.
May 12, 2003... 2003 MAY 12 - (NewsRx.com & NewsRx.net) -- Up to 1.5 million Russians have contracted HIV, the virus that causes AIDS, the nation's top expert on the disease says. AIDS came lately to Russia but spread rapidly as intravenous drug use has...

Investor ask pharma company to lower AIDS drug prices.
May 12, 2003... 2003 MAY 12 - (NewsRx.com & NewsRx.net) -- The mammoth California Public Employees Retirement System (CalPERS) - which holds nearly $760 million in GlaxoSmithKline (GSK) stock - voted unanimously to send a letter to Glaxo CEO Jean-Paul Garnier...

Phenotypic drug susceptibility data correlate with improved long-term outcomes.
May 12, 2003... 2003 MAY 12 - (NewsRx.com & NewsRx.net) -- ViroLogic, Inc. (NASDAQ:VLGC) announced that data from a study published in the journal AIDS support the clinical utility of the company's patented PhenoSense HIV assay for phenotypic analysis of...

DataLogic chosen to provide IT support for Diagnostic Testing.
May 12, 2003... 2003 MAY 12 - (NewsRx.com & NewsRx.net) -- DataLogic International, Inc., (DLGI) announced that it has been awarded a contract with Los Angeles-based Diagnostics Testing to provide services for biological testing as well as other services. ...

Study identifies common viral coinfections among African children with HIV-1.
May 12, 2003... 2003 MAY 12 - (NewsRx.com & NewsRx.net) -- Study identifies common viral coinfections among African children infected HIV-1. "City-dwelling children from Kenya who were infected with human immunodeficiency virus type 1 (HIV-1) were tested...

Theory of planned behavior explains STD risk behaviors of incarcerated women.
May 12, 2003... 2003 MAY 12 - (NewsRx.com & NewsRx.net) -- Investigators have used the theory of planned behavior to understand the STD risk behaviors of incarcerated women. "Women in American correctional facilities make up an at-risk group for STDs/HIV,...

Agreement signed to distribute HIV test kit in The Congo.
May 12, 2003... 2003 MAY 12 - (NewsRx.com & NewsRx.net) -- Medical Services International Inc. (Pink Sheets: MSITF) has signed a five-year agreement with JBL Medic Distributors to act as distributor for The Democratic Republic of Congo. Preliminary...

FDA approves rapid, point-of-care test to detect HIV-1 antibodies.
May 12, 2003... 2003 MAY 12 - (NewsRx.com & NewsRx.net) -- MedMira Inc. (MedMira) (TSX Venture: MIR) announced that the U.S. Food and Drug Administration (FDA) has approved the company's Reveal Rapid HIV-1 Antibody Test, the first and only FDA-approved rapid,...

Integracide A exhibits inhibitory activity against HIV-1 integrase.
May 12, 2003... 2003 MAY 12 - (NewsRx.com & NewsRx.net) -- Integracide A exhibits inhibitory activity against HIV-1 integrase, scientists in New Jersey report. According to a study from the United States, "HIV-1 integrase is a critical enzyme in the...

Structures of Cyanovirin-N complexes explain its unique binding capabilities.
May 12, 2003... 2003 MAY 12 - (NewsRx.com & NewsRx.net) -- Scientists unravel the high-affinity interactions with the viral surface envelope glycoproteins of Cyanovirin-N complexes to explain its unique binding capabilities. According to recent research...

AIDS groups to pressure big pharma to lower cost of Fuzeon.
May 12, 2003... 2003 MAY 12 - (NewsRx.com & NewsRx.net) -- A coalition of AIDS groups from across California, the U.S., Italy, and other parts of the world launched a campaign urging pharmaceutical maker, F. Hoffmann-La Roche to lower the price of its new...

FDA clinical trials of HIV rapid test completed.
May 12, 2003... 2003 MAY 12 - (NewsRx.com & NewsRx.net) -- Efoora, Inc., announced that the U.S. Food and Drug Administration (FDA) Clinical Trials of its Efoora HIV Rapid Test, which were conducted in support of an application for clearance to market the Test...

HIV-positive patients need to take care with food and water safety.
May 12, 2003... 2003 MAY 12 - (NewsRx.com & NewsRx.net) -- Patients infected with HIV need to take particular care to avoid contaminated food and water. "Public health and food safety experts estimate that millions of episodes of illnesses annually can be...

HIV vaccine vectors expressing vaccinia virus IL-15 induce cellular immunity.
May 12, 2003... 2003 MAY 12 - (NewsRx.com & NewsRx.net) -- Co-administration of HIV vaccine vectors with vaccinia viruses expressing IL-15, but not IL-2, induced long-lasting cellular immunity. "Vaccine efficacy is determined largely by cellular and...

Burkina Faso to purchase generic AIDS drugs from Indian company.
May 12, 2003... 2003 MAY 12 - (NewsRx.com & NewsRx.net) -- The Burkina Faso government has signed a contract to purchase generic AIDS drugs from an Indian company, but said the price of treatment remained too high for many. Health Minister Alain Yoda said...

Researchers describe method for identifying distribution of CD30 alleles.
May 12, 2003... 2003 MAY 12 - (NewsRx.com & NewsRx.net) -- According to a study from Australia, researchers have discovered a way to identify the distribution of the CD30 gene promoter microsatellite alleles in healthy and human immunodeficiency virus-1...

Diflucan partnership program launched in Zimbabwe.
May 12, 2003... 2003 MAY 12 - (NewsRx.com & NewsRx.net) -- Zimbabwe's Ministry of Health and Child Welfare and Pfizer Inc. have launched the Diflucan Partnership Program in Zimbabwe, marking Pfizer expansion to 15 countries in Africa and the Caribbean with...

Pneumocystis carinii infection of ear presents as first indication of HIV.
May 12, 2003... 2003 MAY 12 - (NewsRx.com & NewsRx.net) -- Dutch researchers report on the case of a patient whose Pneumocystis carinii infection of the ear was the first manifestation of HIV infection. According to recent research from Netherlands, "We...

Treatment of HIV-1 virions depleted of cyclophilin A restores infectivity.
May 12, 2003... 2003 MAY 12 - (NewsRx.com & NewsRx.net) -- Treatment of HIV-1 virions depleted of cyclophilin A by natural endogenous reverse transcription restores infectivity, scientists in Atlanta report. According to recent research published in the...

Active interfacial peptides inhibit crosslinking of dimeric form of integrase.
May 12, 2003... 2003 MAY 12 - (NewsRx.com & NewsRx.net) -- Active interfacial peptides were found to inhibit crosslinking of the dimeric form of integrase, according to researchers in Indiana. According to recent research published in the journal...

HIV-1 5' leader harbors an internal ribosome entry site.
May 12, 2003... 2003 MAY 12 - (NewsRx.com & NewsRx.net) -- The HIV-1 5' leader harbors an internal ribosome entry site (IRES) capable of driving protein synthesis, researchers in Canada report. "The 5' leader of the human immunodeficiency virus type 1...

Synthesis of novel HIV-1 protease inhibitors based on carbohydrate scaffolds.
May 12, 2003... 2003 MAY 12 - (NewsRx.com & NewsRx.net) -- Scientists have synthesized novel HIV-1 protease inhibitors based on carbohydrate scaffolds. According to a study from Ireland, "The synthesis of peptidomimetic inhibitors of HIV-1 protease based...

Immune responses in HIV-negative women exposed to HIV-infected partner studied.
May 12, 2003... 2003 MAY 12 - (NewsRx.com & NewsRx.net) -- Researchers have investigated the HIV-specific T cell responses to conserved HIV proteins in HIV-seronegative women highly exposed to a single HIV-infected partner. According to a study from the...

Program for adolescent mothers improves anti-infection behaviors, knowledge.
May 12, 2003... 2003 MAY 12 - (NewsRx.com & NewsRx.net) -- A program designed to teach young women about AIDS and preventative measures has significantly improved behaviors and knowledge among participants, researchers in Los Angeles report. "Effects were...

HBV drug resistance in HIV-HBV infected patients calls for close monitoring.
May 19, 2003... 2003 MAY 19 - (NewsRx.com & NewsRx.net) -- Australian researchers have found a drug-resistant strain of the hepatitis B virus (HBV) in a number of hepatitis B and HIV coinfected patients treated with the antiviral agent lamivudine. The...

Ampligen use in HIV treatment shows promise.
May 19, 2003... 2003 MAY 19 - (NewsRx.com & NewsRx.net) -- Data were presented at the 16th International Conference on Antiviral Research that the experimental RNA-based drug Ampligen provides a significant increase in the time interval before HIV rebound that...

HAART can restore CMV-specific immune responses in some infected HIV-1 patients.
May 19, 2003... 2003 MAY 19 - (NewsRx.com & NewsRx.net) -- Immunopathologists from the Pasteur Institute report they've "reconstituted cytomegalovirus (CMV)-specific T-cell responses in human immunodeficiency virus-1 [HIV-1] positive, CMV-positive patients...

Influenza vaccination does not worsen HIV infection.
May 19, 2003... 2003 MAY 19 - (NewsRx.com & NewsRx.net) -- by Maria G. Essig, MS, ELS, senior medical writer - HIV-positive patients who received an influenza vaccination did not experience increases in the HIV viral load or decreases in CD4 T lymphocytes,...

Barrier-to-autointegration factor is HIV-1 preintegration complex component.
May 19, 2003... 2003 MAY 19 - (NewsRx.com & NewsRx.net) -- The barrier-to-autointegration factor is a component of functional HIV-1 preintegration complexes, concluded a recent study. "Retroviral integration in vivo is mediated by preintegration complexes...

HIV-1 genetic recombination is more frequent than that of Moloney MLV.
May 19, 2003... 2003 MAY 19 - (NewsRx.com & NewsRx.net) -- HIV-1 genetic recombination occurs more frequently than in Moloney murine leukemia virus despite the viruses similar template switching rates, study results show. "Retroviral recombinants result...

Counseling reduces risky behavior in HIV-positive people.
May 19, 2003... 2003 MAY 19 - (NewsRx.com & NewsRx.net) -- A year after receiving behavioral counseling about risky sexual behavior, HIV-positive people had two-thirds fewer episodes of unprotected sex with HIV-negative individuals or those who do not know...

Global fight against AIDS requires more than drug cocktails.
May 19, 2003... 2003 MAY 19 - (NewsRx.com & NewsRx.net) -- It will take more than wider access to drugs to win the fight against AIDS in countries where medical and economic resources are limited. What is needed is a combination of affordable anti-HIV...

MedMira receives additional China order for 150,000 Rapid HIV Tests.
May 19, 2003... 2003 MAY 19 - (NewsRx.com & NewsRx.net) -- MedMira, Inc., (MIR) announced that it has received an additional order for 150,000 MiraWell Rapid HIV Tests from its distributor in the south central province of Guangdong in the People's Republic of...

Cross-resistance profile of atazanavir evaluated.
May 19, 2003... 2003 MAY 19 - (NewsRx.com & NewsRx.net) -- Bristol Myers Squibb Co. scientists have evaluated the cross-resistance profile of the company's HIV-1 protease inhibitor (PI) atazanavir (BMS-232632). They tested "551 clinical isolates exhibiting...

Population pharmacokinetics of itraconazole in Thai HIV-1 infected persons.
May 19, 2003... 2003 MAY 19 - (NewsRx.com & NewsRx.net) -- A population pharmacokinetic model of itraconazole in Thai HIV-1 infected patients revealed no differences in drug activity between this cohort and other populations. C.H.W. Koks and colleagues,...

Researchers describe potential of CXCR4 inhibitors as new HIV treatment.
May 19, 2003... 2003 MAY 19 - (NewsRx.com & NewsRx.net) -- Organizers of the 16th International Conference on Antiviral Research have announced the presentation of data supporting the potential of a new class of anti-HIV agents. Dr. Dominque Schols, an...

Study supports value of resistance tests to guide use of newer HIV drugs.
May 19, 2003... 2003 MAY 19 - (NewsRx.com & NewsRx.net) -- ViroLogic, Inc., (VLGC) announced that results of a recent study support the utility of its proprietary drug resistance assays to guide HIV/AIDS treatment with regimens containing the recently marketed...

Electron microscopy aids diagnosis of NRTI-induced toxic effects in liver.
May 19, 2003... 2003 MAY 19 - (NewsRx.com & NewsRx.net) -- Electron microscopy is a valuable tool for diagnosing mitochondrial cytopathies in the liver induced by toxic effects of nucleoside reverse transcriptase inhibitors. According to a study from...

Novel small molecule exhibits in vitro and in vivo efficacy against HIV.
May 19, 2003... 2003 MAY 19 - (NewsRx.com & NewsRx.net) -- Kucera Pharmaceutical Co., a Winston-Salem, North Carolina, spin-off of Wake Forest University's School of Medicine and the University of North Carolina at Chapel Hill, has announced that its founder,...