AIDS Weekly articles from May 1994

AIDS Weekly archives from May 1994

Ten percent HIV-positive rate found among alcoholics.
May 2, 1994... Substance Abuse as Risk Factor Ten percent of the patients in a New York alcohol rehabilitation unit were infected with HIV, according to a recent report ("Undetected HIV Infection among Patients Admitted to an Alcohol Rehabilitation...

HIV vaccine candidate may elicit broader immunity. (Therion Biologics Corp.'s TBC-3B)
May 2, 1994... Vaccines AIDS vaccine researchers at Vanderbilt University Medical Center (VUMC), Nashville, Tennessee, will soon begin testing a new vaccine candidate with the potential to prompt immune responses to more than a single strain of HIV,...

Therion Biologics receives $5 million grant. (from the National Institute of Allergy and Infectious Diseases)
May 2, 1994... Funding Therion Biologics Corporation, Cambridge, Massachusetts, announced that the company has been awarded from the U.S. National Institute of Allergy and Infectious Diseases (NIAID) a $5 million grant to further its AIDS vaccine...

V3-loop peptide conjugates elicit neutralizing antibodies. (HIV vaccines)
May 2, 1994... HIV Vaccines Relatively large peptides from the HIV*1 V3 loop bound to a carrier protein elicit neutralizing antibodies, but smaller, more conserved V3 peptide conjugates do not, a new study shows. The conjugate immunogens consisted...

HIV vaccine development at crossroads.
May 2, 1994... Vaccines The Director of the Division of Research and Intervention Development of the World Health Organization (WHO) Global Program on AIDS, Dr. Peter Piot, has warned that HIV vaccine development is at a crossroads. Speaking at...

Meeting to study ethical considerations for vaccine trials. (HIV vaccines)
May 2, 1994... Vaccine Trials With its upcoming invitational meeting, HIV Preventive Vaccines: Social, Ethical and Political Considerations for Domestic Efficacy Trials, AIDS Action broadens a multidisciplinary discussion of the challenges surrounding...

Vaccines for STDs: possibility or pipe dream? (sexually transmitted diseases)
May 2, 1994... Vaccine Theory Vaccines to prevent bacterial sexually transmitted diseases (STDs) now elude medical science, but "cautious optimism is warranted," advise University of North Carolina (UNC) researchers. Perhaps because they are...

HIV-infected patients should be considered at risk for Legionnaires' disease.
May 2, 1994... Legionnaires' Disease While Legionella pneumophila is an uncommon pathogen for HIV-infected individuals, the organism may produce serious disease in this population, indicated researchers from Texas. HIV-infected individuals should...

Substance use linked to unsafe sex among runaway youth.
May 2, 1994... Risk Reduction HIV/AIDS risk reduction programs among runaway youth need to target the reduction in use of alcohol and other drugs, as well as risky sexual behavior, a team of New York researchers reports ("Alcohol and Drug Use and...

New national lifestyle magazine for people affected by HIV/AIDS debuts. (POZ)
May 2, 1994... New York On March 15, 1994, POZ, a new national lifestyle magazine for people affected by HIV/AIDS, was introduced. Designed by J.C. Suares (who designed 7 Days and Variety), POZ's first issue (April/May) debuted with an interview with...

Wellcome merges research, development.
May 2, 1994... Business Reorganizations British pharmaceuticals company Wellcome, the maker of the AIDS drug AZT, announced it will merge its research and development divisions into one global unit to allow speedier decisions and better efficiency. ...

Recombinant virus assay useful in susceptibility testing. (Wellcome Research Laboratories)
May 2, 1994... Wellcome Research Laboratories The recombinant virus assay can be performed in roughly three weeks, and represents a rapid, nonselective procedure for identification of clinical isolates, according to a report from Wellcome Research...

Clarithromycin generally effective in Mycoplasma.
May 2, 1994... Clarithromycin A study of antibiotic susceptibilities for AIDS -associated Mycoplasma found that clarithromycin was highly active against all six strains tested. Antiviral therapy in patients with AIDS has shown little success....

Consortium launching multi-drug tests on HIV.
May 2, 1994... Multi-Drug Update A consortium of 16 pharmaceutical companies is launching an unusual test to see if a combination of AIDS drugs can control HIV, the Wall Street Journal reported April 14, 1994. AIDS researchers have failed to find...

Avigen announces grant award for anti-viral research. (grant from the National Cooperative Drug Discovery Group of the National Institute of Allergy and Infectious Diseases for capsid targeted viral inactivation)
May 2, 1994... California Avigen Inc., Alameda, California, announced that it is a co-recipient of a research grant award from the National Cooperative Drug Discovery Group of the U.S. National Institutes of Allergy and Infectious Diseases (NIAID) to...

Company on track after FDA advisory committee meeting. (Univax Biologics Inc.; Blood Products Advisory Committee review of WinRho SD for immune thrombocytopenic purpura)
May 2, 1994... Immune Thrombocytopenic Purpura Univax Biologics Inc., Rockville, Maryland, officials said that the U.S. Food and Drug Administration (FDA) Blood Products Advisory Committee meeting was an important step in the regulatory review of...

AIDS is more than a virus. (Dr. Jonathan Mann speech for World Health Week)
May 2, 1994... Viral Issues When the history of the AIDS epidemic is written, it may be considered as much a human rights issue as a health issue, according to the keynote speaker of World Health Week, as reported in the April 8, 1994, issue of the...

Asian business leaders crucial in fight against AIDS. (Dr. Michael Merson speech)
May 2, 1994... AIDS Asian business leaders have a crucial role in the battle to slow the spread of AIDS, according to Dr. Michael Merson, Executive Director, World Health Organization (WHO), Global Program on AIDS. "There's a lot at stake in...

Institute breaks new ground in cancer and AIDS pain. (Roxane Pain Institute)
May 2, 1994... AIDS/Cancer Roxane Laboratories, Columbus, Ohio, announced at the Fifth Cancer Patient Education Conference, held in Pittsburgh, Pennsylvania, April 15, 1994, that it has established the Roxane Pain Institute for cancer- and AIDS-related...

PCP prophylaxis may prolong AIDS survival time. (Pneumocystis carinii pneumonia)
May 2, 1994... Survival Time Survival time among AIDS patients with CD4 counts of 0.20 x 10(9)/L has improved by about one year in the past decade, though survival time using the 1987 case definition has not shown similar improvement, according to a...

Researchers recommend susceptibility to therapy testing. (fluconazole resistance)
May 2, 1994... Fluconazole Resistance Because of the possibility for resistance to fluconazole to develop, the drug should not be used unless a clear therapeutic goal exists, indicated Texas researchers. An appropriate way to monitor the...

The tumor suppressor protein p53 strongly affects HIV-1 replication. (Research Report)
May 2, 1994... AUTHORS: L. Duan, I. Ozaki, J.W. Oakes, K. Khalili and R.J. Pomerantz. Thomas Jefferson University, Department of Medicine, Philadelphia, Pennsylvania. According to an abstract submitted by the authors to a joint meeting of the...

Molecular inhibition of HIV-1 replication by a non-cytopathic HIV-2 provirus. (Research Report)
May 2, 1994... AUTHORS: J. Rappaport, S.K. Arya, A.L. Notkins, M.W. Richardson and P.E. Klotman. U.S. National Institute of Dental Research, Laboratory of Oral Medicine, Bethesda, Maryland. According to an abstract submitted by the authors to a joint...

CT-2576, a synthetic inhibitor of phospholipid signaling suppresses HIV-1 expression in human brain/U1 cell cocultures. (Research Report)
May 2, 1994... AUTHORS: C.C. Chao, G. Gekker, S. Hu, P.K. Peterson, D.W. Leung, S. Bursten and J.W. Singer. University of Minnesota, School of Medicine, Minneapolis, Minnesota; and Cell Therapeutics, Inc., Seattle, Washington. According to an abstract...

TNFs but not IL-10 expression by Mycobacterium avium-infected human monocytes correlates with virulence of M. avium. (tumor necrosis factors; interleukin 10) (Research Report)
May 2, 1994... AUTHORS: H. Shiratsuchi, D.C. Reed and J.J. Ellner. University Hospitals of Cleveland, Cleveland, Ohio. According to an abstract submitted by the authors to a joint meeting of the American Federation for Clinical Research, held April 29...

In-cell PCR applications: non-random combinatorial libraries of human antibodies and detection of HIV-1 transcripts at the single cell level. (polymerase chain reaction) (Research Report)
May 2, 1994... AUTHORS: G. Gorochov, M.J. Embleton, P.T. Jones and G. Winter. MRC Center, Center for Protein Engineering, Cambridge, United Kingdom. According to an abstract submitted by the authors to the Keystone Symposia titled Antibody Engineering:...

Possible mechanism of nucleolar trans-location and activation of HIV-1 Rev protein. (Research Report)
May 2, 1994... AUTHORS: Y. Adachi, T.D. Copeland, E. Afonina, M. Hatanaka, S. Oroszlan and G.N. Pavlakis. Frederick Cancer Research and Development Center, Human Retrovirus Section, Frederick, Maryland; Frederick Cancer Research and Development Center,...

A small element from the Mason-Pfizer monkey virus genome HIV-1 expression and replication Rev-independent. (Research Report)
May 2, 1994... AUTHORS: M. Bray 1, R. Ernst 1, S. Prasad 1, K.-T. Jeang 2, D. Rekosh 1 and M.-L. Hammarskjold 1. 1University of Virginia, Myles H. Thaler Center for AIDS and Retrovirus Research, Charlottesville, Virginia; 2U.S. National Institute of...

HIV-1 Rev is capable of shuttling between the nucleus and cytoplasm. (Research Report)
May 2, 1994... AUTHORS: A. Cochrane and N. Richard. McGill University, Department of Microbiology and Immunology, Montreal, Quebec, Canada. According to an abstract submitted by the authors to the Keystone Symposia titled The Eukaryotic Nucleus, held...

Effects of HIV envelope proteins, gp120 and gp160, on the production of superoxide (O2-) in neutrophils (PMN). (glycoproteins) (Research Report)
May 2, 1994... AUTHORS: S.D. Mertins, P.D. Kind, S.L. Trunk and S.J. Chanock. U.S. National Cancer Institute, Pediatric Branch, Bethesda, Maryland; George Washington University, Washington, D.C. According to an abstract submitted by the authors to a...

Crystal structure of the principal neutralization site of HIV-1. (V3 loop) (Periodical Report) (Abstract)
May 2, 1994... SOURCE: Science, April 1, 1994;264(5155):82-85. According to the authors' abstract of an article published in Science, "The crystal structure of a complex between a 24-amino acid peptide from the third variable (V3) loop of human...

Targeting of liposomes to cells expressing CD4 using glycosylphosphatidylinositol-anchored gp120 - influence of liposome composition on intracellular trafficking. (Periodical Report) (Abstract)
May 2, 1994... SOURCE: Journal of Biological Chemistry, March 25, 1994;269(12):9090-9098. According to the authors' abstract of an article published in the Journal of Biological Chemistry, "To test the concept that glycosylphosphatidylinositol...

Interaction of the HIV-1 fusion peptide with phospholipid vesicles - different structural requirements for fusion and leakage. (Periodical Report) (Abstract)
May 2, 1994... SOURCE: Biochemistry, March 22, 1994;33(11):3201-3209. According to the authors' abstract of an article published in Biochemistry, "This paper presents a study on the membrane fusion activity of a 23-residue synthetic peptide,...

Intracellular analysis of in vitro modified HIV Tat protein. (Periodical Report) (Abstract)
May 2, 1994... SOURCE: Journal of Biological Chemistry, March 18, 1994;269(11):8366-8375. According to the authors' abstract of an article published in the Journal of Biological Chemistry, "Human immunodeficiency viruses HIV-1 and HIV-2 encode a...

Household epidemiology of Cryptosporidium parvum infection in an urban community in northeast Brazil. (Periodical Report) (Abstract)
May 2, 1994... SOURCE: Annals of Internal Medicine, March 15, 1994;120(6):500-505. According to the authors' abstract of an article published in Annals of Internal Medicine, "Objective: To examine the transmission of Cryptosporidium infection in...

Nutrition in HIV infection. (Periodical Report) (Abstract)
May 2, 1994... SOURCE: Current Opinion in Gastroenterology, March 1994;10(2):218-226. According to the authors' abstract of an article published in Current Opinion in Gastroenterology, "Body wasting, characterized by loss of body cell mass, is a...

Factors influencing survival after AIDS - report from the Multicenter AIDS Cohort Study (MACS). (Periodical Report) (Abstract)
May 2, 1994... SOURCE: Journal of Acquired Immune Deficiency Syndromes, March 1994;7(3):287-295. According to the authors' abstract of an article published in the Journal of Acquired Immune Deficiency Syndromes, "The objective of this study was to...

HIV-1 infection incidence among persons with hemophilia in the United States and Western Europe, 1978-1990. (Periodical Report) (Abstract)
May 2, 1994... SOURCE: Journal of Acquired Immune Deficiency Syndromes, March 1994;7(3):279-286. According to the authors' abstract of an article published in the Journal of Acquired Immune Deficiency Syndromes, "We studied human immunodeficiency...

Simian immunodeficiency virus as a model for vaccination against HIV - induction in rhesus macaques of Gag- or Nef-specific cytotoxic T lymphocytes by lipopeptides. (Periodical Report) (Abstract)
May 2, 1994... SOURCE: Journal of Immunology, March 1, 1994;152(5):2530-2537. According to the authors' abstract of an article published in the Journal of Immunology, "The protection against infection by HIV probably requires the induction of both...

A new subtype of human immunodeficiency virus type 1 (MVP-5180) from Cameroon. (Periodical Report) (Abstract)
May 2, 1994... SOURCE: Journal of Virology, March 1994;68(3):1581 -1585. According to the authors' abstract of an article published in the Journal of Virology, "A new subtype (MVP-5180) of human immunodeficiency virus type 1 (HIV-1) was isolated...

Cysteine residues in the Vif protein of human immunodeficiency virus type 1 are essential for viral infectivity. (Periodical Report) (Abstract)
May 2, 1994... SOURCE: Journal of Virology, March 1994;68(3):1714 -1720. According to the authors' abstract of an article published in the Journal of Virology, "The infectivity factor of human immunodeficiency virus type 1 (HIV-1), Vif, contains...

Genomic cloning and complete sequence analysis of a highly divergent African human immunodeficiency virus isolate. (Periodical Report) (Abstract)
May 2, 1994... SOURCE: Journal of Virology, March 1994;68(3):1586 -1596. According to the authors' abstract of an article published in the Journal of Virology, "Analysis of the complete sequence of a human immunodeficiency virus (HIV) isolate...

Viral multiplicity of attachment and its implications for human immunodeficiency virus therapies. (Periodical Report) (Abstract)
May 2, 1994... SOURCE: Journal of Virology, March 1994;68(3):1782 -1789. According to the author's abstract of an article published in the Journal of Virology, "The multiplicity of attachment (MOA) of a virion in any particular time interval is the...

Asia expected to have world's highest rate of HIV by year 2000. (World Health Organization estimates)
May 9, 1994... Global Issues The Tenth International Conference on AIDS, to be held in Yokohama, Japan, August 7-12, 1994, marks the first time that researchers, public health officials, service providers and activists will gather in an Asian nation...

Japan's second largest city lays groundwork for conference. (Yokohama)(X International Conference on AIDS, August 7-12, 1994)
May 9, 1994... X International Conference on AIDS Preparations, including plans for cultural events, public education programs and upgraded visitor facilities, are underway in Yokohama, Japan, for the X International Conference on AIDS, to be held...

Focus is on the family and AIDS. (World Health Organization's World AIDS Day, Dec 1, 1994)
May 9, 1994... World AIDS Day The World Health Organization (WHO) has announced that World AIDS Day 1994 will take AIDS and the family as its theme. In a statement announcing the planned focus, the WHO's Global Program on AIDS said the December 1,...

Children with HIV respond to flu shots. (Northwestern University Medical School, Chicago, IL)
May 9, 1994... At-Risk Populations Children and adolescents with HIV infection respond to influenza vaccination, although absolute antibody titers are lower than those seen in age-matched controls. Data suggest that HIV-infected children should...

Research may have implications for other cancers. (Kaposi's sarcoma)(Vanderbilt Cancer Center)
May 9, 1994... Kaposi's Sarcoma In the early 1980s, the mystery of AIDS began to unravel when physicians in New York and California hospitals started seeing an unusual number of unusually aggressive cases of Kaposi's sarcoma (KS), a rare cancer that...

Research points to drug against genital warts. (GS 504)(Gilead Sciences Inc.)(Penn State's Milton S. Hershey Medical Center)
May 9, 1994... Drug Research A cancer researcher has found evidence that a potential new drug may help eliminate genital warts, the most common sexually transmitted viral disease. John Kreider, M.D., professor of pathology and microbiology and...

Vaccines offer potential for HIV. (naked DNA)(National Institute of Allergy and Infectious Diseases)
May 9, 1994... Naked DNA A new kind of vaccine that uses genes to trigger the body's immune response may emerge as a revolutionary approach in preventing infectious diseases, including AIDS, said a microbiologist from the U.S. National Institute of...

SIV vaccines fail to protect but suppress virus. (simian immunodeficiency virus)(multi-center drug evaluation)
May 9, 1994... Vaccine Development Subunit vaccines against simian immunodeficiency virus (SIV) that fail to protect animals from challenge with infectious virus nevertheless can stimulate strong immune responses that limit infection. These...

Switch from zidovudine to ddI beneficial. (AZT)(didanosine)(Bristol-Myers Squibb AI454-010 Study Group)
May 9, 1994... Antiretroviral Therapy AIDS patients receiving zidovudine and experiencing a decline in their clinical condition benefited from a switch to didanosine (ddI), a recent study reports ("Didanosine Compared with Continuation of Zidovudine in...

Crossover to ddI is most cost-effective in zidovudine-intolerant. (didanosine)(AZT)(University of California, San Diego)(RAND Corp)(University of Southern California)
May 9, 1994... Healthcare Costs Crossover to didanosine (ddI) is the most cost -effective mode of treatment for patients with advanced HIV who have become intolerant of zidovudine, California researchers report ("A Cost Analysis of Approved...

Benefit of zidovudine declines after first year of use. (AZT)(AIDS in Europe Study Group)
May 9, 1994... Antiretroviral Therapy Therapy with zidovudine improves survival among patients receiving the drug for the first year of its use, but by the second year the death rate resembles that of patients who have never received zidovudine,...

Zidovudine use associated with higher healthcare charges. (AZT)(Johns Hopkins University School of Medicine and Maryland Department of Health and Mental Hygiene)
May 9, 1994... Healthcare Costs Zidovudine use is associated with higher lifetime healthcare charges, Maryland researchers report ("Zidovudine Therapy and Health Resource Utilization in AIDS," Journal of Acquired Immune Deficiency Syndromes,...

Thiacetazone no longer appropriate in TB treatment. (in HIV patients)(tuberculosis)(article in Transactions of the Royal Society of Tropical Medicine and Hygiene, Jan-Feb 1994 issue)
May 9, 1994... Treatment Due to the danger of potentially fatal side effects in tuberculosis (TB) patients with HIV infection, thiacetazone is no longer an appropriate treatment, according to a report from Zambia. "We believe that there is enough...

Fluoroquinolones may reduce hepatotoxicity. (in HIV-positive patients with tuberculosis)(Beth Israel Medical Center, New York City)
May 9, 1994... Treatment A three-drug combination of ethambutol, ofloxacin and an aminoglycoside may be a useful alternative therapy for the management of hepatotoxicity in HIV-positive tuberculosis (TB) patients. The ethambutol, ofloxacin,...

Eosinophils alternative marker of immunodepression in TB. (tuberculosis)(letter in Jan-Feb 1994 issue of Transactions of the Royal Society of Tropical Medicine and Hygiene)
May 9, 1994... Tuberculosis Eosinophil counts may be a viable way to mark immunodepression in HIV-positive patients with tuberculosis (TB) living in developing countries, according to a report from a French research center. Active TB is one of the...

Researchers suggest management strategy for HIV exposure. (Beth Israel Medical Center, New York)
May 9, 1994... HIV Prophylaxis New York researchers presented a management strategy that may be relevant in view of increasing antiretroviral drug resistance among HIV-infected patients. Donna Mildvan, Beth Israel Medical Center, New York, and...

FDA issues statement. (Food and Drug Administration warnings on Latero-Flora and Flora-Balance manufactured by Bio-Genesis Inc.)
May 9, 1994... Health Warning The U.S. Food and Drug Administration (FDA) warned consumers not to take the liquid form of two unapproved drug products - Latero-Flora and Flora-Balance, manufactured by Bio-Genesis Inc. - because they have been found to...

Newly discovered monkey virus may help with human virus. (simian parvovirus)(Bowman Gray School of Medicine)
May 9, 1994... Parvovirus Researchers at the Bowman Gray School of Medicine have discovered a new monkey virus that potentially may have great importance for people. Dr. M. Gerard O'Sullivan, a veterinary pathologist and assistant professor of...

Maternal HIV-1 infection associated with premature birth. (study in Nairobi, Kenya)
May 9, 1994... Vertical Transmission Maternal infection with HIV-1 is associated with premature birth and postpartum endometritis, an international team of researchers reports ("Maternal Human Immunodeficiency Virus-1 Infection and Pregnancy Outcome,"...

International experts focus on street children. (Street Children and Substance Abuse program)(World Health Organization-sponsored meeting in Geneva)
May 9, 1994... Substance Abuse The growing international problem of street children and substance abuse is the focus of a meeting at the headquarters of the World Health Organization (WHO) in Geneva, Switzerland, to be attended by more than one hundred...

Playboy pitches condoms in Taiwan. (condom manufacturer Malaysia Borneo Finance Corp under license from Playboy)
May 9, 1994... Condom Issues Promising to "make all the mystique and excitement of the Playboy lifestyle available to consumers," Playboy launched a line of colorful condoms in Taiwan. "We chose Taiwan as the first country to launch our line of...

New York City subways. (advertising wars between the Gay Men's Health Crisis safe sex campaign and the Catholic League's abstinence campaign)
May 9, 1994... Condom Dispute New York City's famous subway system will become the stage for a morality play and the battleground for the fight over AIDS prevention when the Catholic League posts 2,500 pro-abstinence advertisements June 1, 1994. ...

Procysteine enhances glutathione levels in phase I/II trial. (clinical trial results reported in April 1994 issue of Journal of Acquired Immune Deficiency Syndromes)
May 9, 1994... Clinical Trials Intravenous administration of l-2-Oxothiazolidine-4 -carboxylic Acid (OTC; Procysteine) at doses of 100 mg/kg enhance levels of glutathione and cysteine in the peripheral blood mononuclear cells (PBMC) of asymptomatic...

Viral burden at seroconversion correlates with progression. (multi-center study reported in April 1994 issue of Journal of Acquired Immune Deficiency Syndromes)
May 9, 1994... Viremia The degree of HIV viral burden at seroconversion correlates with progression of disease, reports a California research team ("Circulating HIV-1-Infected Cell Burden from Seroconversion to AIDS: Importance of Postseroconversion...

BACTEC contraindicated for mycobacterial blood cultures. (BACTEC 12B culture medium)(Wake Forest University Medical Center and North Carolina Baptist Hospital)
May 9, 1994... Blood Cultures The use of the Isolator blood culture tube with BACTEC 12B medium is contraindicated for mycobacterial blood cultures, suggested researchers from North Carolina. While the incidence of mycobacteremia previously was...

Report on viral safety of Alphanine SD. (Alpha Therapeutic Corp)(Coagulation Factor IX)
May 9, 1994... Viral Issues Alpha Therapeutic Corporation, Los Angeles, California, reported that results from its special study of Alphanine SD, Coagulation Factor IX, appeared to confirm the absence of hepatitis A virus in final product. Data from...

New definition increases caseload and probability of survival. (Centers for Disease Control and Prevention definitions of AIDS)(research by Istituto Superiore di Sanita and University of Tor Vergata, Rome, Italy)
May 9, 1994... 1993 Case Definition The new U.S. Centers for Disease Control and Prevention (CDC) case definition of AIDS increases the number of cases, and survival for the patients recognized by the new classification is considerably longer than that...

Immuno-CTM active against Cryptosporidium in animal tests. (Biomune Systems Inc.)
May 9, 1994... Antimicrobial Applications Biomune Systems Inc., Salt Lake City, Utah, announced that its Immuno-CTM product showed statistical significance in eradicating cryptosporidium in experimentally infected mice. Cryptosporidiosis has...

Nutrition, supplement and exercise program gets positive results. (in HIV-positive people with wasting syndrome and malnutrition)(BeneFit supplement manufactured by Health Management Resource)
May 9, 1994... Diet Issues A pilot program testing the effectiveness of a newly -developed enteral supplement (BeneFit) and lifestyle intervention in counteracting malnutrition and wasting syndrome has generated promising early results. People...

Vivid statistics. (increase in number of HIV-positive pregnant women in Nigeria)(Graphic Report) (Illustration)
May 9, 1994... According to an article published in the journal Tropical and Geographical Medicine, Vol. 46, No. 1, 1994, the seroprevalence of HIV is on the increase among pregnant women in Maiduguri, Nigeria. An earlier study done at the antenatal clinics...

Zidovudine to be offered to lab workers infected on job. (AZT)(Then: AIDS Weekly, March 13, 1989)(Outcomes Report)
May 9, 1994... The U.S. National Institutes of Health says it will provide zidovudine to laboratory workers who become infected with HIV because of their work. A one-page safety memo to employees at 70 affiliated laboratories from the institutes' office of...

No HIV seroconversions found among 33 exposed health care workers. (Now: AIDS Weekly, April 11, 1994)(Outcomes Report)
May 9, 1994... Preliminary results of a prospective serologic follow-up study showed that no HIV seroconversions occurred among 33 occupationally exposed healthcare workers, Danish researchers reported. None of the healthcare workers was given zidovudine as...

Anti-HIV-1 activity of hydroxyurea in combination with 2',3'dideoxynucleosides. (ddI and ddC)(Research Report)
May 9, 1994... AUTHORS: W.Y. Gao, D.G. Johns and H. Mitsuya. U.S. National Cancer Institute, Bethesda, Maryland. According to an abstract submitted by the authors to a joint meeting of the American Federation for Clinical Research, held April 29 -...

Toxoplasmosis of the central nervous system in patients with AIDS. (Research Report)
May 9, 1994... AUTHORS: C. Del Rio, A. Orzechowski and G. Sanchez -Mejorada. Hospital Angeles del Pedregal, Mexico City, Mexico. According to an abstract submitted by the authors to a joint meeting of the American Federation for Clinical Research, held...

Relative incidence of infection during neutropenia - a retrospective comparison between HIV+ patients with ANC < 500 and ANC = 500-750. (absolute neutrophil count)(Research Report)
May 9, 1994... AUTHORS: K. Yu and R. Mitsuyasu. University of California, Los Angeles, California. According to an abstract submitted by the authors to a joint meeting of the American Federation for Clinical Research, held April 29 - May 2, 1994, in...

Neutropenia is an independent risk for bacteremia in AIDS. (Research Report)
May 9, 1994... AUTHORS: P. Keiser and E. Higgs. University of Texas, Southwestern Medical Center, Dallas, Texas; and Veterans Administration Medical Center, Dallas, Texas. According to an abstract submitted by the authors to a joint meeting of the...

Serum retinol levels do not correlate with survival in hospitalized patients with advanced HIV-1 infection. (Research Report)
May 9, 1994... AUTHORS: D.W. Haas, S. Raffanti and F. Chytil. Vanderbilt University, Nashville, Tennessee. According to an abstract submitted by the authors to a joint meeting of the American Federation for Clinical Research, held April 29 - May 2,...

Hospital admissions of HIV-infected patients from 1988-1992 in Maryland. (Research Report)
May 9, 1994... AUTHORS: I. Fortnang and R.D. Moore. Johns Hopkins University, Baltimore, Maryland. According to an abstract submitted by the authors to a joint meeting of the American Federation for Clinical Research, held April 29 - May 2, 1994, in...

HIV-specific cytotoxic T-lymphocytes (CTL) and CD4 T-cell loss - greater gag-specific killing is correlated with less rapid decline in CD4 number. (Research Report)
May 9, 1994... AUTHORS: T.C. Greenough, D.B. Brettler, A. Forsberg, P. Forand, M.M. McManus, B. Blais, R. Hudson and J.L. Sullivan. University of Massachusetts, Worcester, Massachusetts; and Medical Center of Central Massachusetts, Memorial Hospital,...

Combination therapy for cryptococcal disease. (fluconazole and flucytosine)(Research Report)
May 9, 1994... AUTHORS: R. Larsen. University of Southern California Medical Center, Los Angeles, California. According to an abstract presented by the author to the 3rd annual meeting entitled Focus on Fungal Infections, held April 1-2, 1994, in...

Aspergillosis in AIDS patients. (Research Report)
May 9, 1994... AUTHORS: D.W. Denning. Monsall Hospital, Manchester, United Kingdom. According to an abstract presented by the author to the 3rd annual meeting entitled Focus on Fungal Infections, held April 1-2, 1994, in Tucson, Arizona, "Over the...