AIDS Weekly articles from June 2004

AIDS Weekly archives from June 2004

Aldo-keto reductase family pathway generates HP1 from S-1360.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- The aldo-keto reductase family pathway generates HP1 from S-1360. According to a study published in the journal Chemico-Biological Interactions, "S-1360, a 1,3-diketone derivative, was the first HIV...

Phlorotannins from brown alga E. cava inhibit HIV-1 RT and protease.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Phlorotannins from the brown alga E. cava inhibit HIV-1 reverse transcriptase and protease. "The bioassay-directed isolation of a marine brown alga, Ecklonia cava, afforded four phlorotannin...

HIV-1 viral load and infectivity reduced in presence of cellular prion protein.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- HIV-1 viral load and infectivity is reduced in the presence of cellular prion proteins. According to a study from France, "The cellular prion protein (PrPc) is highly conserved in mammals and...

HCV therapy with IFN/RBV relatively safe in patients coinfected with HIV and HCV.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- HCV therapy with interferon plus ribovarin is relatively safe in patients coinfected with HIV and HCV. According to a study from the American Foundation for AIDS Research, "Human immunodeficiency...

Novel synthesis of protease inhibitors yield potent anti-HIV activity.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Novel synthesis of protease inhibitors yield potent anti-HIV activity. "Novel indium-mediated radical cyclization reactions of aliphatic iodoalkynes have been studied. Treatment of iodoalkynes with...

Scientists discover how AIDS opens cell doors.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Researchers at the Salk Institute have discovered a way to view viruses like HIV upon cell entry. Published in the May 18 edition of the Proceedings of the National Academy of Sciences, this...

Small study shows weekly cycles of anti-HIV drugs successful.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- A small study conducted at the U.S. National Institutes of Health (NIH) showed that treatment of HIV-infected patients with a once-daily regimen of anti-HIV drugs given in pre-planned, 7-day-on,...

Antibody light chain cleaves chemokine receptor CCR-5 peptide.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Researchers report the discovery of a catalytic antibody light chain capable of cleaving a chemokine receptor CCR-5 peptide with a high reaction rate constant. "A monoclonal antibody (MAb), ECL2B-2,...

Nucleoside analogues and mitochondrial toxicity reviewed.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Scientists review nucleoside analogues and mitochondrial toxicity in a recent issue of Clinical Infectious Diseases. "An evaluation of the U.S. Food and Drug Administration's Adverse Event...

HIV replication reduced in cells with zinc finger transcription factor.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Primary human cells with a designed zinc finger transcription factor show attenuated HIV-1 replication. "Small molecule inhibitors of human immunodeficiency virus, type 1 (HIV-1) have been...

Health workers in Uganda need training to help teens with sexual health issues.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- For young people in northern Uganda, health workers are an important source of sexual and reproductive health information. But a study finds health workers in the region need more training and...

New compounds antifungal and anticancer but inactive against HIV-1 and bacteria.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- New alpha-(N)-heterocyclichydrazones have antifungal and anticancer properties but are inactive against HIV-1 and bacteria. According to recent research from Italy, "A series of 3- and...

Company reports on test of VScan Tuberculosis test kit.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Medical Services International, Inc., (MSITF) has completed a major independent test of its VScan Tuberculosis (TB) rapid test kit in Europe. The test results showed that the VScan TB test kit had...

Cryptosporidium parvum genome completely sequenced.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- The Cryptosporidium parvum genome has been completely sequenced. "The apicomplexan Cryptosporidium parvum is an intestinal parasite that affects healthy humans and animals, and causes an...

Biopharmaceutical company granted licenses to develop HIV resistance drugs.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Samaritan Pharmaceuticals Inc. (SPHC) announced that Georgetown University has granted two exclusive worldwide licenses to Samaritan to develop and market Samaritan Research Lab's HIV investigational...

HIV vaccine trial initiated by U.S. Army based on Therapore technology.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Avant Immunotherapeutics, Inc., (AVAN) announced that the Walter Reed Army Institute of Research (WRAIR) has initiated a phase I clinical trial to assess the safety and immunogenicity of an HIV vaccine...

New HIV clinical program with Alferon LDO launched in Africa.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Hemispherx Biopharma, Inc., (HEB) has entered into an agreement with the World Foundation Aids Research and Prevention to launch a clinical trial in HIV with its experimental product Alferon LDO, a...

Referral testing agreement signed for HIV phenotypic resistance testing.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- ViroLogic, Inc., (VLGC) has signed an expanded referral testing agreement with Quest Diagnostics (DGX), under which Quest Diagnostics will make ViroLogic its preferred provider of HIV phenotypic...

Active nuclear factor kappa-B (P50) inhibitors bind strongly to DNA.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Active nuclear factor kappa-B (P50) inhibitors bind strongly to DNA. "Nuclear Factor-kappa B (NF-kappaB) is an inducible transcription factor of the Rel family, and is sequestered in the cytoplasm...

Reactive species intimately associated with AIDS-Kaposi sarcoma pathogenesis.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Reactive species is intimately associated with AIDS-Kaposi sarcoma pathogenesis. "AIDS-related Kaposi's sarcoma (AIDS-KS), which is the most prevalent AIDS related cancer, arises in a unique...

Immune and endocrine change with group intervention in early stage HIV infection.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Immune and endocrine changes are associated with group intervention in early stages of HIV infection. According to a study published in the International Journal of Group Psychotherapy, "There has...

Pharmacological CDK inhibitors target virus and pathogenic mechanisms.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Pharmacological CDK inhibitors target the virus and the pathogenic mechanisms. According to a study from Canada, "Cyclin-dependent kinases (CDKs) are required for replication of adeno-, papilloma-...

LA adult film industry resumes production.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Vivid Entertainment Group, the nation's top adult movie maker, has resumed new movie production nearly a month after a performer's positive test for the AIDS virus prompted a self-imposed moratorium...

HIV-1 nucleocapsid protein enhances annealing approximately fivefold.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- HIV-1 nucleocapsid protein enhances annealing approximately fivefold. "HIV-1 reverse transcriptase uses human tRNA[superscript]Lys,3 as a primer to initiate reverse transcription. Prior to...

Autologous p2<sup>gag peptide blocks HIV-1 virion autolysis.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Autologous p2gag peptide blocks HIV-1 virion autolysis. "Our previous study suggested that the p2gag peptide, AEAMSQVTNTIM, inhibits human immunodeficiency virus type 1 (HIV-1) protease (PR)...

Crystal structures of HIV protease mutants reveal indinavir-binding site changes.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Crystal structures of HIV protease mutants reveal indinavir-binding site changes. "The crystal structures of the wild-type HIV-1 protease (PR) and the two resistant variants, PRV82A and PRL90M, have...

HIV-1 APIs modulate Ca[superscript]2+ signaling in secretory epithelial cells.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- HIV-1 aspartyl protease inhibitors modulate Ca[superscript]2+ signaling in secretory epithelial cells. "Aspartyl protease inhibitors (APIs) effectively extend the length and quality of life in...

Prolonged HIV-1 culture increases its sensitivity to soluble CD4 neutralization.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Prolonged HIV-1 culture increases its sensitivity to soluble CD4 neutralization. "Primary strains of human immunodeficiency virus type 1 (HIV-1) are known to adapt to replication in cell lines in...

Tenofovir regimens increase K65R selection to confer multiple NRTI resistance.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Tenofovir regimens increase K65R selection to confer multiple nucleoside reverse transcriptase inhibitor resistance. According to recent research published in the journal Antimicrobial Agents and...

Microsimulation model predicts HIV spread with and without condom use.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- A microsimulation model predicts HIV spread with and without condom use. Researchers from Australia report the use of a microsimulation model "to assess the potential impact of condom use on women's...

AIDS medicine price hike may lead to licenses to other companies.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Abbott Laboratories' decision to quadruple the price of its AIDS drug Norvir has the government thinking about an unprecedented action, allowing other companies to make the medicine that was discovered...

Big pharmaceutical companies pledge to work on AIDS drug.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- The Bush administration announced a new initiative to speed up the approval process for new combination AIDS drugs that will bring cheap, easy-to-use treatment to millions of people in Africa and the...

Body composition changes more prominent in HIV-infected patients on HAART.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Body composition changes are more prominent in HIV-infected patients on highly active antiretroviral therapy. According to recent research published in the Scandinavian Journal of Infectious...

HIV-1 non-B subtype likely to develop rapid resistance following HAART.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- HIV-1 non-B subtypes are likely to develop rapid resistance following highly active antiretroviral treatment. "Effective antiretroviral treatment (ART) has significantly reduced the morbidity and...

State AIDS drug plans offering widely varying benefits.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Patients with HIV or AIDS get widely varying government aid for prescription drugs depending on where they live, according to a recently released study. In North Carolina, people who earn more than...

HBV DNA test should replace HBsAg and/or anti-HBc for blood donor screening.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- The hepatitis B virus DNA test should replace HBsAg and/or anti-HBc for blood donor screening. "Prevention of transfusion-transmitted hepatitis B virus (HBV) has historically relied on serological...

Transmission cycles of Pneumocystis jirovecii infections are linked.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Transmission cycles of Pneumocystis jirovecii infections are linked. "To date, investigations of Pneumocystis jirovecii circulation in the human reservoir through the dihydropteroate synthase (DHPS)...

Organized clinics most successful in implementing HIV QI programs.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Organized clinics are the most successful in implementing HIV quality improvement programs. According to a study from Canada, investigators "examined a quality improvement (QI) program, offered to...

New Mexico syphilis cases increase.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- A steady increase in New Mexico's syphilis rates are alarming state health officials. The number of cases remains small, but the increase has been dramatic in recent years. In 1999, 21 cases of...

Reproductive health program failed to better sexual health in Uzbekistan.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- A reproductive health program failed to better sexual health in Uzbekistan. "Since 1991, contraceptive use has risen significantly in Uzbekistan while reliance on abortion has declined, yet...

Data on first Fuzeon international consensus guidelines published.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- International consensus guidelines for Fuzeon (enfuvirtide), the first and only fusion inhibitor available for the treatment of HIV, were published in AIDS, the official journal of the International...

Efavirenz induces strong inhibition of SREBP-1c-dependent lipogenic pathway.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Efavirenz induces a strong inhibition of the SREBP-1c-dependent lipogenic pathway. According to recent research from France, "A serious metabolic syndrome combining insulin-resistance,...

HIV/AIDS disproportionately affects African American women.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- The Black Women's Health Imperative used HIV Vaccine Awareness Day, May 18, 2004, as an opportunity to educate African American women about the impact of HIV/AIDS on them and to help them learn more...

Priority review granted for fixed-dose co-formulation of Viread, Emtriva for HIV.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Gilead Sciences (GILD) announced that the U.S. Food and Drug Administration (FDA) has granted priority review status to the New Drug Application (NDA) for the fixed-dose co-formulation of the company's...

Prevalence and severity of anemia increases with advancing HIV disease.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- "In patients with human immunodeficiency virus (HIV), anemia is a commonly encountered hematologic abnormality that has a significant impact on clinical outcomes and quality of life (QOL). This review...

Institute receives $3.5 million for AIDS vaccine research.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Researchers at the Vaccine and Gene Therapy Institute (VGTI) and the Oregon National Primate Research Center at Oregon Health and Science University have received a $3.5 million grant from the U.S....

Researchers explore gene treatment to obliterate HIV before it does damage.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Doctors may someday have a new way to combat AIDS by going straight to the source: destroying the virus before it has a chance to wreak havoc on a patient's immune system. Thomas Merigan, MD, the...

Ravuconazole lysine phosphoester effective against pulmonary aspergillosis.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Ravuconazole lysine phosphoester is effective against pulmonary aspergillosis. According to recent research published in the journal Antimicrobial Agents and Chemotherapy, "Ravuconazole is a new...

Settlement reached in HIV inmates' healthcare suit.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- A settlement has been reached in a lawsuit against the Alabama Department of Corrections and its former medical provider, claiming HIV-positive inmates at Limestone Correctional Facility were not given...

MedMira signs Canadian distributor to market Rapid HIV Test Kits.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- MedMira, Inc., (MIR) and Source Medical Corp. of Toronto, Canada, have reached an agreement for Source Medical to be the exclusive distributor of the MedMira Reveal Rapid HIV test within Canada. ...

Novel microarrays detect multple pathogens in serum.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- A novel microarray-based immunoassay enables serological detection of multiple pathogens. Researchers in France developed "novel peptide-protein microarrays, which were fabricated using...

Semicarbazide and amine slides compared in peptide-protein microarray assay.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- The utility of different types of glass slides have been compared in a novel microarray assay. In the journal Bioconjugate Chemistry, researchers in France described "the preparation of...

Medicine price hike highlights controversy of government funding drug research.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Abbott Laboratories' decision to quadruple the price of its AIDS drug Norvir has the U.S. government thinking about an unprecedented action - allowing other companies to make the medicine that was...

ReceptoPharm completes first step in production of RPI-78M.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Nutra Pharma Corp., (NPHC) a biotechnology holding company that owns rights to patents and intellectual property related to the development of drugs for HIV and multiple sclerosis, announced that its...

A. fumigatus variant has decreased susceptibility to multiple antifungals.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Aspergillus fumigatus variant has decreased susceptibility to multiple antifungals. "Isolates of Aspergillus fumigatus that demonstrate resistance to itraconazole (ITZ) have been described...

Cholesterol modulates P-glycoprotein activity in human PBMC.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Cholesterol modulates P-glycoprotein activity in human PBMC. "P-glycoprotein (P-gp) is expressed in a wide range of cell types including peripheral blood mononuclear cells (PBMCs) where it may...

EBV-induced growth proliferation inhibited by nuclear antigen EBNA2-TAT peptide.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Epstein-Barr virus-induced growth proliferation is inhibited by nuclear antigen EBNA2-TAT peptide. "Epstein-Barr virus (EBV) causes infectious mononucleosis and is associated with cancers in...

Pharmaceutical company closes $18.3M Series C financing.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Panacos Pharmaceuticals Inc. has closed a $18,300,000 Series C financing led by prior investors Ampersand Ventures and A. M. Pappas & Associates. New investors in this round include Mitsui & Co....

Structural character of siRNA important determinant of siRNA efficiency.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- The structural character of siRNA is an important determinant of siRNA efficiency. "The concept of small interfering RNA (siRNA) has been extended to include not only short double-stranded RNA of...

p65 peptide identified that selectively inhibits NF-kappa B activation.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- A p65 peptide has been identified that selectively inhibits NF-kappa B activation. "Because of the critical role of the nuclear transcription factor NF-kappaB in inflammation, viral replication,...

Phase III trial with 1% C31G vaginal gel initiated.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Biosyn, Inc., announced that it has commenced enrollment in a phase III pivotal clinical trial of its lead drug candidate, 1% C31G vaginal gel, for the reduction of sexual transmission of human...

Missed goals, dwindling participation leads Pittsburgh to cancel AIDS walk.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Faced with recent declines in participation and missed fund-raising goals, organizers of the Pittsburgh AIDS Walk said this will be the last year for the walk. The Pittsburgh AIDS Task Force blames...

AIDS advocates praise President Clinton's efforts since leaving office.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Three years after leaving office, Bill Clinton is starting to show AIDS activists the leadership they wanted to see during his presidency. While some of Clinton's work is criticized as "Hollywood"...

COX-2 inhibition and AT[subscript]1R blockade treatment for chronic nephropathy.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- COX-2 inhibition and AT[subscript]1R blockade may be a useful treatment for chronic nephropathy. "Chronic renal injury can be mediated by angiotensin II (ANG II) and prostanoids through...

Aetna withdrawing lawsuit against Abbott over AIDS drug.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Aetna is dropping its lawsuit accusing Illinois-based Abbott Laboratories Inc. of seeking a monopoly on AIDS drugs by raising the price of its popular drug Norvir by 400%. The Hartford-based...

Biopharmaceutical company appoints new executive director, regulatory affairs.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- The Immune Response Corporation (IMNR) announced that David C. Mitchell has joined the company as executive director, regulatory affairs. Mitchell assumes a new company position and will be...

Panel hears arguments over cost of AIDS drug.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- A United States National Institutes of Health (NIH) panel heard sharply differing views May 25, 2004, on whether the government should step in and allow other companies to start making a popular AIDS...

Attorney says he'll comply with court order in arsenic case.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- A North Carolina attorney gave up his long fight to keep private conversations with a now-dead client about the 2000 arsenic death of an AIDS researcher. Richard Gammon complied with a judge's...

Human DNA polymerase-eta is a reverse transcriptase.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Human DNA polymerase-eta is a reverse transcriptase. "We have proposed previously that error-prone reverse transcription using pre-mRNA of rearranged immunoglobulin variable (IgV) regions as...

FDA sets new rules on who can donate human tissue.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- People who donate sperm, eggs and other commonly transplanted tissues will have to be screened for infectious diseases like blood donors are, under long-awaited federal rules. Donated blood and...

Chemokine receptor may not play direct role in placental HIV transmission.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- The chemokine receptor CXCR4 may not play a direct role in HIV transmission in the placenta, study findings suggest. According to A. Kumar and colleagues at the All India Institute of Medical...

Ezrin/CD95 linkage key role regulating susceptibility to CD95-mediated apoptosis.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Ezrin/CD95 linkage has a key role regulating susceptibility to CD95-mediated apoptosis. According to published research from Italy, "CD95(APO-1/Fas)-mediated apoptosis of bystander uninfected T...

Intracellularly expressed HIV-1 Tat protein inhibits neural cell proliferation.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Intracellularly expressed HIV-1 Tat protein inhibits neural cell proliferation. "Human immunodeficiency virus type I Tat protein is one of the soluble neurotoxins. Most studies have to date focused...

Timed ablation of regulatory CD4+ T cells prevents AIDS progression.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Timed ablation of regulatory CD4+ T cells prevents AIDS progression in mice. According to scientists from Australia, "Successful immunotherapy of murine AIDS (MAIDS) in C57BL/6J mice based on the...

Cell surface targets identified for HIV-1 therapeutics using genetic screens.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Cell surface targets are identified for HIV-1 therapeutics using genetic screens. "Human immunodeficiency virus (HIV) drugs designed to interfere with obligatory utilization of certain host cell...

Dendritic cell-associated function impairment distinguish HCV and HIV infection.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Dendritic cell-associated function impairment distinguishes HCV and HIV infection. "Impaired APC functions may play important roles in chronicity of hepatitis C virus (HCV) and HIV infections. To...

Volunteers needed as more AIDS vaccines move into clinical trials.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- In a major step forward, the AIDS vaccine field is now moving a large number of experimental AIDS vaccine candidates into human clinical trials around the world, the AIDS Vaccine Advocacy Coalition...

Megestrol acetate improves appetite and weight gain in cancer and AIDS patients.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Mmegestrol acetate improves appetite and weight gain in cancer and AIDS patients. "This study aimed to assess the efficacy and safety of megestrol acetate (MA) in anorexia-cachexia syndrome (ACS)....

Medically assisted reproduction still risky in presence of chronic viral disease.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Medically assisted reproduction is still risky in the presence of chronic viral diseases. According to a study from Belgium, "Teams practicing medically assisted reproduction techniques try to...

Cytokine flow cytometry assesses cellular immune responses to viral antigens.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Cytokine flow cytometry assesses the cellular immune responses to viral antigens. "Considerable attention has been focused on CD8 and CD4 T cell responses as a major element of the cellular immune...

Inverse correlation between CD27 quantitation and cytotoxic effector function.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- There is an inverse correlation between CD27 quantitation and cytotoxic effector function. "Phenotypic classification of human CD8+ T cells using three cell surface markers, CD27, CD28 and CD45RA,...

Virologist receives NIH grant to continue investigation of HIV dementia complex.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Jay Rappaport, PhD, a member of Temple University's Center for Neurovirology and Cancer Biology has been awarded a 5-year, $2 million grant from the U.S. National Institutes of Health to continue his...

NIH awards $1.8 million for study on coping with HIV/AIDS.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- The number of older Americans living with HIV/AIDS is growing, but many lack access to services that would help them cope with the challenges of the disease: depression, thoughts of suicide, lack of...

RAPD analysis useful for genotyping clinical Candida spp. isolates.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- RAPD analysis may be useful for genotyping clinical Candida spp. Isolates. According to a study from Brazil, "The patterns of genetic variation of samples of Candida spp. isolated from patients...