AIDS Weekly articles from June 2003

AIDS Weekly archives from June 2003

Interleukin-12, cholera toxin adjuvants enhance glycoprotein vaccine.
June 2, 2003... 2003 JUN 2 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in the United States have identified a pair of adjuvants which enhance the performance of an HIV glycoprotein-based vaccine. Diana I. Albu and...

Modified gagpol fusion gene highly immunogenic in animals.
June 2, 2003... 2003 JUN 2 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - A novel fusion of the HIV gag and pol genes is highly immunogenic in animals, researchers in California report. "Results of both natural history studies and...

COX-2 plays key role in gp120 neurotoxicity.
June 2, 2003... 2003 JUN 2 - (NewsRx.com & NewsRx.net) -- COX-2 helps mediate the neurotoxic effects of the HIV coat protein gp120. According to recent research from Italy, "the human CHP100 neuroblastoma cell line has been shown to provide an useful in...

Low adiponectin levels linked to HAART-induced insulin resistance.
June 2, 2003... 2003 JUN 2 - (NewsRx.com & NewsRx.net) -- Low adiponectin levels may play a role in insulin resistance induced by HIV treatment. "Highly active antiretroviral therapy (HAART) has dramatically reduced HIV-related mortality, but is associated...

Novel agent disrupts viral capsid protein function.
June 2, 2003... 2003 JUN 2 - (NewsRx.com & NewsRx.net) -- A novel antiviral agent disrupts the activity of the HIV capsid protein. "During the assembly stage of the human immunodeficiency virus (HIV) replication cycle, several thousand copies of the viral...

Oxidized DNA metabolite levels do not rise during antiretroviral treatment.
June 2, 2003... 2003 JUN 2 - (NewsRx.com & NewsRx.net) -- Oxidized DNA metabolite levels do not rise during antiretroviral treatment for HIV. "Mitochondrial toxicity of nucleoside analogues has been proposed to be the etiology of a range of side-effects...

Independent study reveals that Rapid HIV-1 Antibody Test has 100% sensitivity.
June 2, 2003... 2003 JUN 2 - (NewsRx.com & NewsRx.net) -- MedMira, Inc., (MIR) announced that Brown University, in conjunction with Walter Reed Army Institute of Research, has completed an independent sensitivity study of MedMira's Reveal Rapid HIV-1 Antibody...

Interaction between HIV, alcohol, may accelerate disease progression.
June 2, 2003... 2003 JUN 2 - (NewsRx.com & NewsRx.net) -- In the United States, alcohol problems appear to be more prevalent among people with the human immunodeficiency virus (HIV) than among the general population. Both alcohol abuse and HIV infection are...

Substance-abusing men place wives at high risk.
June 2, 2003... 2003 JUN 2 - (NewsRx.com & NewsRx.net) -- Substance-abusing men who engage in behavior that puts them at high risk for direct exposure to HIV are likely to put their wives at high risk for indirect HIV exposure through unprotected sexual...

Novel primate cell line useful for research.
June 2, 2003... 2003 JUN 2 - (NewsRx.com & NewsRx.net) -- A novel primate cell line may aid research on HIV and its simian counterpart (SIV). The "susceptibility of HSC-F, a cynomolgus macaque cell line immortalized by Herpesvirus saimiri, to infection...

Protein tyrosine kinases involved in gp120-induced neuron death.
June 2, 2003... 2003 JUN 2 - (NewsRx.com & NewsRx.net) -- Protein tyrosine kinases play a role in neurodegeneration caused by the HIV coat protein gp120. HIV gp120 "is able to kill neuronal cells in culture," according to researchers in Italy who examined...

Viral Tat protein toxic only to uninfected astrocytes.
June 2, 2003... 2003 JUN 2 - (NewsRx.com & NewsRx.net) -- The HIV Tat protein is highly neurotoxic, but only to uninfected cells. Tat "has been implicated in the neuropathogenesis of HIV infection," researchers in the United States explained. "However,...

Sustained-release bupropion effective.
June 2, 2003... 2003 JUN 2 - (NewsRx.com & NewsRx.net) -- Sustained-release bupropion shows promise for the treatment of depression in HIV patients. Researchers at the University of Miami conducted a study "to evaluate the efficacy and tolerability of...

Heterochromatin involved in viral integration.
June 2, 2003... 2003 JUN 2 - (NewsRx.com & NewsRx.net) -- Heterochromatin is involved in HIV integration during latent - but not active - infection. "The presence of latent reservoirs has prevented the eradication of human immunodeficiency virus (HIV) from...

Adiponectin loss alters fat distribution during chronic infection.
June 2, 2003... 2003 JUN 2 - (NewsRx.com & NewsRx.net) -- Adiponectin loss is involved in fat distribution changes during chronic HIV infection. "HIV-related lipodystrophy is characterized by adipose redistribution, dyslipidemia, and insulin resistance,"...

Seasonal flux seen in Pneumocystis carinii pneumonia rate.
June 2, 2003... 2003 JUN 2 - (NewsRx.com & NewsRx.net) -- The rate of Pneumocystis carinii pneumonia (PCP) varies by season. PCP "remains a serious opportunistic infection in HIV infected individuals," immunologists in England explained. "Seasonal changes...

YY1 transcription factor lowers CCR5 expression.
June 2, 2003... 2003 JUN 2 - (NewsRx.com & NewsRx.net) -- The YY1 transcription factor reduces cellular levels of the HIV coreceptor CCR5. Expression of this molecule "is regulated by a number of transcription factors," scientists in Japan explained. ...

American guidelines for HAART initiation appropriate.
June 2, 2003... 2003 JUN 2 - (NewsRx.com & NewsRx.net) -- The recently adopted American guidelines for initiating antiretroviral therapy in HIV patients are a good standard. "The appropriate immunologic stage of human immunodeficiency virus infection at...

Fatigue in HIV-positive patients often has treatable causes.
June 2, 2003... 2003 JUN 2 - (NewsRx.com & NewsRx.net) -- Fatigue in HIV-positive patients often has a treatable cause. According to a study from the United States, "To describe prevalence of fatigue and its correlates among persons with HIV infection, we...

HIV-1 escapes attack by changes in carbohydrate structures.
June 2, 2003... 2003 JUN 2 - (NewsRx.com & NewsRx.net) -- HIV-1 escapes attack by changing the structure of its carbohydrate moieties. According to recent research from the United States, "HIV-1 readily mutates to escape the immune response, evolving in...

Virion core structure elucidated.
June 2, 2003... 2003 JUN 2 - (NewsRx.com & NewsRx.net) -- The structure of the HIV virion core has been elucidated. "Mature, infectious HIV-1 particles contain a characteristic cone-shaped core that encases the viral RNA and replication proteins,"...

Hepatitis A vaccine does not affect course of HIV.
June 2, 2003... 2003 JUN 2 - (NewsRx.com & NewsRx.net) -- Hepatitis A vaccination did not affect the course of HIV infection in HIV-positive patients. "The safety and immunogenicity of inactivated hepatitis A (HepA) vaccine was assessed in 133 hepatitis A...

Anti-HIV drugs save vision, improve outlook for AIDS patients.
June 2, 2003... 2003 JUN 2 - (NewsRx.com & NewsRx.net) -- A new study from Johns Hopkins researchers shows the multiple anti-HIV drug regimen called highly active antiretroviral therapy (HAART) saves eyesight as well as lives. A second study led by Johns...

Early neurodevelopmental markers predict mortality.
June 2, 2003... 2003 JUN 2 - (NewsRx.com & NewsRx.net) -- Neurodevelopmental markers are indicative of mortality risk for infants infected with HIV. In a study from the United States, 157 "vertically infected HIV-1 positive infants (85 males, 72 females)...

Virus-specific CD8 cell function often impaired in young children.
June 2, 2003... 2003 JUN 2 - (NewsRx.com & NewsRx.net) -- HIV-specific cytotoxic T-cell function is often impaired in young seropositive children with low CD4 cell counts. "The immunology of vertical HIV transmission differs from that of adult infection...

Expert says treatment for slowing AIDS virus might help.
June 2, 2003... 2003 JUN 2 - (NewsRx.com & NewsRx.net) -- The SARS virus apparently attacks people's cells in a manner similar to the AIDS virus, which may offer clues for finding the best drugs to treat the newly discovered disease, an AIDS researcher says....

Navajo Nation battles syphilis, HIV with rare public campaign.
June 2, 2003... 2003 JUN 2 - (NewsRx.com & NewsRx.net) -- Jonathan Iralu shakes his head in frustration when he recalls the week that four Navajo patients came in for checkups at his bustling hospital - and all got the same alarming diagnosis. Each had...

Study finds AIDS virus strain crossed into humans by 1940.
June 2, 2003... 2003 JUN 2 - (NewsRx.com & NewsRx.net) -- One form of the virus that causes AIDS made the jump from animals to people by 1940, a new analysis indicates. HIV-2 didn't spread across West Africa until the 1960s, perhaps spurred by a war in...

SIV from multiple lineages can infect human macrophages.
June 2, 2003... 2003 JUN 2 - (NewsRx.com & NewsRx.net) -- Simian immunodeficiency viruses from multiple lineages can infect human macrophages, indicating the potential for cross-species transmission. "Zoonotic transfer of simian immunodeficiency virus...

DNA priming improves HSV-1 amplicon vector immunogenicity.
June 9, 2003... 2003 JUN 9 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - DNA priming improves the immunogenicity of herpes simplex virus-based vectors expressing HIV proteins, researchers in the United States report. "A single...

Hyperglycosylated gp120 mutants may induce broad humoral responses.
June 9, 2003... 2003 JUN 9 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Polymorphic forms of the HIV coat protein gp120 may elicit broad humoral responses, researchers in the United States say. "The ability to induce broadly...

Low plasma nerve growth factor levels linked to B-cell loss.
June 9, 2003... 2003 JUN 9 - (NewsRx.com & NewsRx.net) -- Low plasma levels of nerve growth factor (NGF) may underlie memory B-cell loss during HIV infection. NGF "regulates B-cell activation and differentiation and is an autocrine survival factor for...

Calpain plays role in viral re-activation.
June 9, 2003... 2003 JUN 9 - (NewsRx.com & NewsRx.net) -- The protease calpain is involved in activation of latent HIV infection. According to published research from Japan, "treatment of OM10.1 cells latently infected with human immunodeficiency virus...

Caffeine inhibits retroviral DNA integration.
June 9, 2003... 2003 JUN 9 - (NewsRx.com & NewsRx.net) -- Retroviral DNA integration is inhibited by caffeine treatment. "Caffeine is an efficient inhibitor of cellular DNA repair, likely through its effects on ATM (ataxia telangiectasia mutated) and ATR...

Novel lipopeptide protease inhibitors reduce resistance risk.
June 9, 2003... 2003 JUN 9 - (NewsRx.com & NewsRx.net) -- A novel series of lipopeptide protease inhibitors reduce the chance of HIV resistance mutations. According to a recent study from France, "the structure of new lipopeptides targeting the enzymic...

Vaccine to be developed will be directed against multiple HIV antigens.
June 9, 2003... 2003 JUN 9 - (NewsRx.com & NewsRx.net) -- BioVex announced that it has signed a letter of intent with the Vaccine Research Center at the National Institutes of Allergy and Infectious Disease, National Institutes of Health, in relation to the...

Memory problems increase patients' wish to die.
June 9, 2003... 2003 JUN 9 - (NewsRx.com & NewsRx.net) -- Patients with advanced AIDS who suffer from problems like memory loss or failing coordination are significantly more likely to wish for an early death than patients without these problems, according to...

Botswana to begin trials for AIDS vaccine on humans.
June 9, 2003... 2003 JUN 9 - (NewsRx.com & NewsRx.net) -- Botswana is scheduled to begin tests on an AIDS vaccine to find out if it is safe when given to healthy adults, officials say. The experimental vaccine, which has already been tested successfully...

Many Americans think an HIV/AIDS vaccine already exists.
June 9, 2003... 2003 JUN 9 - (NewsRx.com & NewsRx.net) -- Many Americans wrongly believe that a preventive vaccine for HIV/AIDS has already been developed, according to surveys recently conducted by the National Institute of Allergy and Infectious Diseases...

Vaccine induces HIV-specific immune response in chronic infection.
June 9, 2003... 2003 JUN 9 - (NewsRx.com & NewsRx.net) -- A controversial vaccine against HIV has been shown to stimulate a critical part of the HIV-specific immune response in chronically infected patients. The small study conducted by researchers at...

Past abuse is related to poor mental health in HIV-positive women.
June 9, 2003... 2003 JUN 9 - (NewsRx.com & NewsRx.net) -- Women with HIV who are young, in poor physical health, in conflict with others, and who have been physically abused by a partner in the past are at greater risk for developing mental health and drug...

Trimeris announces 2003 first quarter results.
June 9, 2003... 2003 JUN 9 - (NewsRx.com & NewsRx.net) -- Trimeris, Inc. (NASDAQ:TRMS) has reported a loss of $15.9 million or $.75 per share, compared with a loss of $17.7 million or $.97 per share in the comparable 2002 period. The decrease in net loss...

Pressure groups call on countries to fund project to treat AIDS, malaria, TB.
June 9, 2003... 2003 JUN 9 - (NewsRx.com & NewsRx.net) -- A global project that offered hope to the victims of diseases that kill 6 million people a year is in danger of collapsing because the world's richest countries have failed to finance it, pressure...

Mink cells susceptible to productive HIV infection.
June 9, 2003... 2003 JUN 9 - (NewsRx.com & NewsRx.net) -- Mink cells are susceptible to productive HIV infection, raising the possibility that minks could be useful in animal studies. "In vivo studies for understanding viral transmission and replication,...

Norepinephrine not involved in murine neurodegeneration.
June 9, 2003... 2003 JUN 9 - (NewsRx.com & NewsRx.net) -- The neurotransmitter norepinephrine (NE) does not mediate neurodegeneration during the murine version of AIDS. Researchers in New York "previously reported that murine AIDS [MAIDS] produces a...

Virus-induced NMDA receptor activation may play role.
June 9, 2003... 2003 JUN 9 - (NewsRx.com & NewsRx.net) -- Activation of NMDA receptors may contribute to HIV-induced neurodegeneration. In a recent study from the University of Nebraska, "the final pathways for neuronal injury in human immunodeficiency...

Flavopiridol restores normal kidney function in animals.
June 9, 2003... 2003 JUN 9 - (NewsRx.com & NewsRx.net) -- Flavopiridol restores normal kidney function in animals with HIV-related nephropathy. "Cumulative evidence suggests that human immunodeficiency virus-associated nephropathy (HIVAN), the third...

DC-SIGN can facilitate and inhibit cell entry and fusion.
June 9, 2003... 2003 JUN 9 - (NewsRx.com & NewsRx.net) -- DC-SIGN can both facilitate and inhibit HIV cell entry and virus-induced cell fusion. This molecule, "a lectin expressed on dendritic cell and macrophage subsets, binds to human immunodeficiency...

Acute retroviral syndrome symptoms have prognostic value.
June 9, 2003... 2003 JUN 9 - (NewsRx.com & NewsRx.net) -- Acute retroviral syndrome (ARS) symptoms can predict HIV disease progression. "The incubation and duration" of ARS "have been associated with progression to AIDS," scientists in France noted. ...

Genetic factors not useful for prognosis.
June 9, 2003... 2003 JUN 9 - (NewsRx.com & NewsRx.net) -- Genetic factors are not useful for predicting HIV progression or related mortality. According to published research from Netherlands, "a model was constructed that estimates the probability of an...

Viral cytopathicity heightened in advanced disease.
June 9, 2003... 2003 JUN 9 - (NewsRx.com & NewsRx.net) -- Viral cytopathicity increases with HIV disease progression. "The presence of only non-syncytium-inducing beta-chemokine receptor 5-restricted (R5/NSI) human immunodeficiency virus type 1 (HIV-1) in...

Antiretroviral-related dyslipidemia linked to atherosclerosis.
June 9, 2003... 2003 JUN 9 - (NewsRx.com & NewsRx.net) -- Dyslipidemia can contribute to atherosclerosis development in HIV patients on antiretroviral therapy. In a recent study from France, researchers "used ultrasonography to measure carotid artery...

Extended viral kinetic models may improve treatment efficacy.
June 9, 2003... 2003 JUN 9 - (NewsRx.com & NewsRx.net) -- Extended models of HIV kinetics may improve the efficacy of antiretroviral therapy. "Clinical markers in the peripheral blood guide the treatment of human immunodeficiency virus type I (HIV-1),"...

Interleukin-2 ineffective for restoring innate antiviral immunity.
June 9, 2003... 2003 JUN 9 - (NewsRx.com & NewsRx.net) -- The cytokine interleukin (IL)-2 does not restore anti-HIV immune activity in seropositive patients. Treatment with IL-2 "has frequently resulted in the restoration of CD4 lymphocyte counts but not...

Fetal peripheral blood cells efficiently metabolize AZT.
June 9, 2003... 2003 JUN 9 - (NewsRx.com & NewsRx.net) -- Fetal peripheral blood cells efficiently metabolize the antiretroviral agent zidovudine, better known as AZT. In a recent study, researchers in Israel "compared the phosphorylation rate of...

Study confirms a treatment for pulmonary hypertension secondary to HIV infection.
June 9, 2003... 2003 JUN 9 - (NewsRx.com & NewsRx.net) -- United Therapeutics Corporation (NASDAQ:UTHR) has announced that the Spanish Review of Cardiology reported the results of a one-year study in which United Therapeutics'lead product, Remodulin,...

CCR5 expression determines neonatal monocyte/macrophage susceptibility.
June 9, 2003... 2003 JUN 9 - (NewsRx.com & NewsRx.net) -- Expression of CCR5 determines the HIV infection risk of neonatal monocytes and macrophages. "The stage of maturation of monocytes affects their susceptibility to HIV infection," scientists in the...

CDC 2002 guidelines for sexually transmitted disease treatment released.
June 9, 2003... 2003 JUN 9 - (NewsRx.com & NewsRx.net) -- Implications of the changes in the CDC 2002 guidelines for sexually transmitted disease treatment are detailed in a report published in the Journal of Midwifery and Women's Health. According to a...

Protective gene mutation found in some HIV patients.
June 9, 2003... 2003 JUN 9 - (NewsRx.com & NewsRx.net) -- Mayo Clinic researchers have identified a naturally occurring "good guy" for patients infected with HIV. It is a helpful gene mutation that impairs the HIV virus' cell-killing machinery, thus preserving...

Scientists engineering better approach to HIV treatment with designer molecules.
June 9, 2003... 2003 JUN 9 - (NewsRx.com & NewsRx.net) -- Ravi Kane, assistant professor of chemical engineering at Rensselaer Polytechnic Institute, is designing brand-new molecules that may one day fend off an HIV infection. Bolstering the body's...

Factors limiting weight gain during pregnancy identified.
June 9, 2003... 2003 JUN 9 - (NewsRx.com & NewsRx.net) -- Malaria infection and low CD4 cell counts are among the factors limiting weight gain in pregnant HIV-positive women. "Progression of HIV disease is often accompanied by weight loss and wasting,"...

Other viral infections common among HIV-infected women.
June 9, 2003... 2003 JUN 9 - (NewsRx.com & NewsRx.net) -- Other viral infections are common among HIV-infected and high-risk HIV-uninfected women. According to a study from the United States, "Viruses that can persist in the host are of special concern in...

Adenovirus Gag vector with CRL1005 adjuvant effective in macaques.
June 16, 2003... 2003 JUN 16 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in the United States have identified an HIV vaccine regimen which elicits potent cellular immunity in non-human primates. "Cellular immune...

Prime-boost regimens with flu, vaccinia virus vectors effective in animals.
June 16, 2003... 2003 JUN 16 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Prime-boost HIV vaccine regimens using influenza and vaccinia virus vectors are effective in animal models, researchers say. "Vaccines that elicit...

Study identifies triggers for risky sex among gay men.
June 16, 2003... 2003 JUN 16 - (NewsRx.com & NewsRx.net) -- Gay men who have poor communication skills and feel unable to protect themselves against HIV infection are more likely to engage in risky sexual behaviors, according to newly released data. The...

Scientists uncover HIV escape route from drugs and vaccines.
June 16, 2003... 2003 JUN 16 - (NewsRx.com & NewsRx.net) -- Virologists at Jefferson Medical College may have discovered a new way by which HIV can evade both antiviral drugs and vaccines. Researchers had reported last summer that a protein called CEM15 is...

Hepatitis C virus prevents HAART-induced immune deactivation.
June 16, 2003... 2003 JUN 16 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus (HCV) prevents immune deactivation in HIV patients treated with antiretroviral agents. The impact of HCV coinfection "on the kinetics of serum beta 2-microglobulin levels in...

Once-daily antiretroviral therapy safe, effective.
June 16, 2003... 2003 JUN 16 - (NewsRx.com & NewsRx.net) -- Once-daily antiretroviral therapy regimens are safe and effective for the treatment of HIV infection. In a recent study, scientists in Spain "analyzed the available evidence about the efficacy and...

AIDS cases growing among black Arkansans.
June 16, 2003... 2003 JUN 16 - (NewsRx.com & NewsRx.net) -- New AIDS cases among blacks in Arkansas increased nearly 60% between 2000 and 2002, while the number of new cases among whites dropped about 27%. Officials say the rising infection rate in the...

HIV-AIDS screening method could become national model.
June 16, 2003... 2003 JUN 16 - (NewsRx.com & NewsRx.net) -- Earlier and more accurate diagnosis of acute infection with HIV, the virus that causes AIDS, is not only possible but also practical - by pooling blood samples from people being screened for HIV and...

Many Americans think an HIV/AIDS vaccine already exists.
June 16, 2003... 2003 JUN 16 - (NewsRx.com & NewsRx.net) -- Many Americans wrongly believe that a preventive vaccine for HIV/AIDS has already been developed, according to surveys recently conducted by the National Institute of Allergy and Infectious Diseases...

Most people at risk for HIV do not use condoms.
June 16, 2003... 2003 JUN 16 - (NewsRx.com & NewsRx.net) -- Nearly two-thirds of people who are at high risk for HIV infection say that they do not use condoms with their regular partners, according to a new study. Only 35.8% of the study participants who...

Sub-Saharan African AIDS initiative announced.
June 16, 2003... 2003 JUN 16 - (NewsRx.com & NewsRx.net) -- Global Med Technologies, Inc., (GLOB) announced that it is working very closely with the Safe Blood for Africa Foundation (SBFA), a 501(c)(3) not-for-profit organization, as one of the companies...

Licensing agreement announced for antiviral compound MIV-210.
June 16, 2003... 2003 JUN 16 - (NewsRx.com & NewsRx.net) -- GlaxoSmithKline (GSK) and Medivir announced that they have signed a licensing agreement for MIV-210, a nucleoside analogue reverse transcriptase inhibitor (NRTI) that has recently begun phase I...

NIH awards grant for T-helper cell-expanding virus vaccine.
June 16, 2003... 2003 JUN 16 - (NewsRx.com & NewsRx.net) -- The U.S. National Institutes of Health (NIH) has awarded an HIV grant to Antigen Express for its T-helper cell-expanding virus vaccine. This $357,000 NIH small business innovative research (SBIR)...

New drug enfuvirtide shows promise against drug-resistant HIV infection.
June 16, 2003... 2003 JUN 16 - (NewsRx.com & NewsRx.net) -- The new drug enfuvirtide, a member of a new class of medications designed to combat HIV, shows strong promise in treating drug-resistant cases of the life-threatening infection, a study conducted with...

Treatment for cocaine addiction may reduce HIV risk.
June 16, 2003... 2003 JUN 16 - (NewsRx.com & NewsRx.net) -- Cocaine addiction has previously been linked to an increased risk of contracting HIV, mainly as a result of sharing contaminated injection equipment, unprotected sex, exchange of sex for drugs,...

ART provides bright future for HIV-positive men but less successful for women.
June 16, 2003... 2003 JUN 16 - (NewsRx.com & NewsRx.net) -- Assisted reproduction can safely help HIV-positive men to become fathers without infecting their partners, according to new research from French fertility experts. But, the news is not so good for...

Study profiles HIV patients who best comply with medication schedules.
June 16, 2003... 2003 JUN 16 - (NewsRx.com & NewsRx.net) -- In a study to assess the effects of age, substance abuse, and neuropsychological function on adherence to antiretroviral treatment among HIV-infected adults, researchers found that patients over the...

Phase II clinical trials for ThGRF in HIV-related lipodystrophy begin.
June 16, 2003... 2003 JUN 16 - (NewsRx.com & NewsRx.net) -- Theratechnologies (TSX:TH) announced that it has enrolled a first patient in a new Phase II clinical study for ThGRF, its growth hormone-releasing factor analogue, in HIV-related lipodystrophy, a...

Juvenile detainees push envelope on HIV/AIDS risk behaviors.
June 16, 2003... 2003 JUN 16 - (NewsRx.com & NewsRx.net) -- Nearly all juvenile jail detainees - even those as young as 10 years - engage in dangerous HIV and AIDS risk behaviors, a finding that poses serious public health problems and presents additional...

Broad product license acquired for breakthrough DNA-based vaccine.
June 16, 2003... 2003 JUN 16 - (NewsRx.com & NewsRx.net) -- In a windfall step that prominently places the company at the center of DNA-based HIV vaccine development, CytRx Corporation (CYTR) announced it has licensed, from the University of Massachusetts...

Novel murine model improves study of Tat-induced neurodegeneration.
June 16, 2003... 2003 JUN 16 - (NewsRx.com & NewsRx.net) -- A novel transgenic murine model can improve the study of brain damage induced by the HIV Tat protein. Viral Tat "is a key pathogenic factor in a variety of acquired immune deficiency syndrome...

Routine testing not useful for psychiatric patients.
June 16, 2003... 2003 JUN 16 - (NewsRx.com & NewsRx.net) -- Routine HIV testing may not be useful for psychiatric patients. Researchers in south India conducted "an anonymous, unlinked study" involving "1160 consecutive, newly registered, adult psychiatric...