AIDS Weekly articles from June 1994

AIDS Weekly archives from June 1994

Five subjects in vaccine study acquire HIV infection.
June 13, 1994... DATELINE: HIV Vaccines At least five volunteers in the U.S. government's principal AIDS immunization study have become infected with the virus, despite having been vaccinated, the Chicago Tribune reported. The matter raises concerns...

State Medicaid programs need national guidance on HIV/AIDS.
June 13, 1994... DATELINE: Healthcare Costs National standards are needed to guide state Medicaid programs in formulating policies regarding drug therapies for HIV/AIDS, according to a recent survey of affiliates of the American Pharmaceutical Association...

Jails qualify as healthcare facilities, expert says. (Robert R. Smith)
June 13, 1994... DATELINE: Workplace Jails are healthcare facilities under the new regulations governing control of TB in the workplace currently being enforced by the U.S. Occupational Safety and Health Administration (OSHA), according to an expert in...

FDA approves combination tuberculosis drug. (Food and Drug Administration, Rifater)
June 13, 1994... DATELINE: Drug The U.S. Food and Drug Administration approved a new three-in-one tuberculosis (TB) pill in an effort to fight the increasingly drug-resistant disease. Rifater, developed by Marion Merrell Dow Inc., combines the...

HPMPC useful in treating infections of HIV. (acyclin nucleoside-phosphonate derivitive)
June 13, 1994... DATELINE: Mucocutaneous Infections An acyclic nucleoside phosphonate known as HPMPC appears to be useful in the topical treatment of immunocompromised patients with herpes simplex virus (HSV)-related mucocutaneous infections that are...

Prognosis for rifampin-resistant M. kansasii excellent. (Mycobacterium kansasii)
June 13, 1994... DATELINE: Mycobacterial Infection The prognosis for cure of infection due to rifampin -resistant Mycobacterial kansasii with chemotherapy alone is excellent, although the number of cases appears to be increasing due, in part, to the HIV...

Botanists study plants as cure for AIDS and cancer. (Botanical Research Institute of Texas)
June 13, 1994... DATELINE: Endangered Plant Life Botanists from around the world went to Texas to plan the final stage of an inventory of plants in the Philippines, where undiscovered potential cures for AIDS and cancer are in danger of dying off. ...

Health experts warn of Chinese AIDS explosion, call for education. (Chinese health experts)
June 13, 1994... DATELINE: Warning In China's frankest admission yet of the dangers it faces from AIDS, health experts warned the country could suffer an explosion in the number of cases unless it starts far-reaching public education. Research...

Acetaminophen use may enhance zidovudine absorption. (AZT)
June 13, 1994... DATELINE: Case Report Long-term use of acetaminophen may enhance the absorption of zidovudine, report researchers from the Netherlands ("Pharmacokinetics of Zidovudine and Acetaminophen in a Patient on Chronic Acetaminophen Therapy,"...

Edinburgh drug users engaging in safer usage practices.
June 13, 1994... DATELINE: At-Risk Populations Drug users in Edinburgh, Scotland, appear to be engaging in safer using behavior, according to a report from staff at the Lothian Board of Health ("Edinburgh Drug Users: Are They Injecting and Sharing...

High incidence of non-AIDS death among HIV-positive IDUS. (injecting drug users)
June 13, 1994... DATELINE: At-Risk Populations Nearly 20 percent of HIV-positive injecting drug users (IDUs) die of causes other than AIDS, according to a report from The Netherlands ("High Mortality among HIV -Infected Injecting Drug Users Without AIDS...

CSW intervention less than successful in Thai sex establishments. (commercial sex worker)
June 13, 1994... DATELINE: At-Risk Populations The Thai government's "100 Percent Condom Campaign," an intervention aimed at commercial sex workers (CSW) and their clients, is apparently meeting with something less than its desired effectiveness,...

Condom use rises and so does sexually transmitted disease. (Jamaica)
June 13, 1994... DATELINE: STD Condom use in Jamaica is rising rapidly but health officials are worried that women are using the contraceptive not to prevent unwanted pregnancies, but to halt the spread of sexually transmitted diseases (STDs),...

Institute to test new AIDS drug. (University of Pittsburgh Medical Center's Pitt Treatment Evaluation Unit, 935U83)
June 13, 1994... DATELINE: Drug The University of Pittsburgh Medical Center's Pitt Treatment Evaluation Unit (PTEU) is recruiting volunteers to test a new drug against HIV. The PTEU is one of four sites in the United States involved in the clinical...

Program to help address substance abuse. (educational video series, Womansource HIV, part 2)
June 13, 1994... DATELINE: Drug Abuse The second part of Womansource HIV, an educational video series developed for HIV-infected women and their service providers by Burroughs Wellcome Company, Research Triangle Park, North Carolina, is being made...

Company announces receipt of $210,000 milestone. (ImmuCell Corp. receives money from Univax Biologics, Inc. for AIDS research)
June 13, 1994... DATELINE: Funding ImmuCell Corporation announced that, as part of the ongoing CryptoGAM development program, Univax Biologics Inc. of Rockville, Maryland ("Univax"), has made a $210,000 milestone payment to ImmuCell. ImmuCell and...

FDA warns of contaminated drug products. (Food and Drug Administration, Latero-Flora and Flora-Balance)
June 13, 1994... DATELINE: Bacterial Infection Two unapproved drug products, Latero-Flora and Flora -Balance, have been found contaminated with bacteria and could cause death, the U.S. Food and Drug Administration (FDA) warned. The drugs are sold...

Study: high levels of depressive distress among gay blacks.
June 13, 1994... DATELINE: Social Issues An unprecedented national study of African-American homosexually active men and women paints a portrait of a segment of society that suffers substantially higher levels of stress and depression than is suffered in...

Analytical assay development for Costatolide (NSC661122) and 7,8 dihydrocostatolide (NSC661123), potential anti-HIV agents. (Research Report)
June 13, 1994... AUTHORS: R.A. Newman, M. Costa and A. Fuentes. University of Texas, M.D. Anderson Cancer Center, Houston, Texas. According to an abstract submitted by the authors to the Eighty-Fifth Meeting of the American Association for Cancer...

Identification of a human cytoplasmic exonuclease - implication in the activity of nucleoside analogs against human immunodeficiency virus type 1.
June 13, 1994... AUTHORS: V. Skalski, S-H Liu and Y-C Cheng. Yale University, School of Medicine, New Haven, Connecticut. According to an abstract submitted by the authors to the Eighty-Fifth Meeting of the American Association for Cancer Research,...

Interaction of novel 2',3'-dideoxy-beta-L-cytosine nucleoside triphosphates with human immunodeficiency virus type 1 reverse transcriptase.
June 13, 1994... AUTHORS: V. Skalski, S-H Liu, T-S Lin and Y-C Cheng. Yale University, School of Medicine, New Haven, Connecticut. According to an abstract submitted by the authors to the Eighty-Fifth Meeting of the American Association for Cancer...

Constitutive expression of human immunodeficiency virus type 1 (HIV-1) tat gene inhibits IL-2 and IL-2 receptor (IL-2R) expression in a human CD4+ T (H-9) cell line. (interleukin 2)
June 13, 1994... AUTHORS: P. Leland 1, B.B. Aggarwal 2 and R.K. Puri1. 1Center for Biologics Evaluation and Research, Division of Cellular and Gene Therapies, Bethesda, Maryland; and 2University of Texas, M.D. Anderson Cancer Center, Houston, Texas. ...

An analysis of educational intervention on health care utilization by HIV+/AIDS infected patients. (Research Report)
June 13, 1994... AUTHORS: R.L. Lynch, V.M. Reddy and S.C. Zell. No Institution Provided. According to an abstract submitted by the authors to the HIV Clinical Trials Conference, held March 24-25, 1994, in Alexandria, Virginia, "Education of...

Clinical and therapeutic HIV monitoring using quantitative nucleic acid analyses. (Research Report)
June 13, 1994... AUTHORS: J.G. Huisman 1, S. Bruisten 1, M. Koppelman 1, A.E. Loeliger 2, M.C. Hermus 1, N. Cool 1, P. Reiss 2 and B. Van Gemen 3. 1Netherlands Blood Transfusion Service, Central Laboratory, Amsterdam, Netherlands; 2National AIDS Therapy...

Inhibition of HIV activity by a noncytotoxic solution of ozone, HOCl-, OCl-, and Cl. (Research Report)
June 13, 1994... AUTHORS: R.E. Morrow, L. Cullman and W.D. Welch. Medical Discoveries, Inc., Salt Lake City, Utah; Microbiology Reference Laboratory, Cypress, California; and Western Medical Clinical Laboratories, Inc., Woodland Hills, California. ...

Nucleotide composition as a driving force in the evolution of retroviruses. (Periodical Report) (Abstract)
June 13, 1994... SOURCE: Journal of Molecular Evolution, May 1994;38(5):506-532. According to the authors' abstract of an article published in the Journal of Molecular Evolution, "All complete retrovirus sequences in the GenEMBL database were...

Effects of the tat basic domain on human immunodeficiency virus type 1 transactivation, using chemically synthesized tat protein and tat peptides. (Periodical Report) (Abstract)
June 13, 1994... SOURCE: Journal of Virology, May 1994;68(5):3343-3353. According to the authors' abstract of an article published in the Journal of Virology, "To study the structure relationship of different Tat domains, the full-length Tat protein...

Evolution of the human immunodeficiency virus type 2 envelope gene in preimmunized and persistently infected Rhesus macaques.
June 13, 1994... SOURCE: Journal of Virology, May 1994;68(5):3415-3420. According to the authors' abstract of an article published in the Journal of Virology, "The V3 and V4 domains of human immunodeficiency virus type 2 (HIV-2) env genes from 14...

Extensive envelope heterogeneity of simian immunodeficiency virus in tissues from infected macaques. (Periodical Report) (Abstract)
June 13, 1994... SOURCE: Journal of Virology, May 1994;68(5):3129-3137. According to the authors' abstract of an article published in the Journal of Virology, "The extent of virus genetic variation within tissues and peripheral blood mononuclear...

Induction of a major histocompatibility complex class 1-restricted cytotoxic T-lymphocyte response to a highly conserved region of human immunodeficiency virus type 1 (HIV-1) gp120 in seronegative humans immunized with a candidate HIV-1 vaccine.
June 13, 1994... SOURCE: Journal of Virology, May 1994;68(5):3145-3153. According to the authors' abstract of an article published in the Journal of Virology, "Efforts to induce broadly reactive immunity against human immunodeficiency virus type 1...

Mutagenic study of codons 74 and 215 of the human immunodeficiency virus type-1 reverse transcriptase, which are significant in nucleoside analog resistance. (Periodical Report) (Abstract)
June 13, 1994... SOURCE: Journal of Virology, May 1994;68(5):3421-3424. According to the authors' abstract of an article published in the Journal of Virology, "Mutation in the human immunodeficiency virus type 1 reverse transcriptase (RT) at codon...

Native oligomeric human immunodeficiency virus type 1 envelope glycoprotein elicits diverse monoclonal antibody reactivities. (Periodical Report) (Abstract)
June 13, 1994... SOURCE: Journal of Virology, May 1994;68(5):3015-3026. According to the authors' abstract of an article published in the Journal of Virology, "We synthesized and purified a recombinant human immunodeficiency virus type 1 (HIV-1)...

Preliminary program announced. (X International Conference on AIDS)
June 20, 1994... X International Conference on AIDS The organizers of the X International Conference on AIDS, to be held in Yokohama, Japan, August 7-12, 1994, announced the preliminary program for the conference. The conference will be attended by...

Kaposi drug value questioned. (Kaposi's sarcoma, sulfated polysaccharide peptidoglycan)
June 20, 1994... Kaposi's Sarcoma A new study sharply questions the reported early promise of a drug for treating Kaposi's sarcoma (KS). Authors of the study say a 1992 report that found the drug effective in animal studies was highly flawed. They...

Test may predict the effectiveness of AZT. (zidovudine)
June 20, 1994... AZT Update A new test may be able to determine whether an HIV -infected individual will respond to AZT therapy. The test was developed by University of Cincinnati (UC), Ohio, researchers Amadeo J. Pesce, Ph.D., director of...

AZT OK during pregnancy. (zidovudine)
June 20, 1994... AIDS Drug Update A study's preliminary findings show the use of the AIDS-fighting drug AZT during pregnancy is safe for the fetus, the U.S. Centers for Disease Control and Prevention (CDC) said. AZT is not yet approved for use...

Company reports discovery of oligonucleotide. (Triplex Pharmaceuticals Corp.)
June 20, 1994... New Discovery Scientists at Triplex Pharmaceutical Corporation announced that they have discovered a series of guanine -rich oligonucleotides which appear to inhibit the function of HIV. The research was reported in the June 1994...

Endogenous retroviruses linked to disease, test developer says. (Howard Urnovitz of Calypte Biomedical)
June 20, 1994... Medical Hypotheses The developer of a test for so-called human endogenous retroviruses (HERVs) suggests that the retroviruses implicated in AIDS - HIV-1 and HIV-2 - may be just part of the AIDS picture. According to Dr. Howard...

Trial of rhIL-12 for HIV-infected persons to begin. (recombinant human interleukin-twelve)
June 20, 1994... Clinical Trial The University of California, Los Angeles (UCLA), Center for AIDS Research and Education (CARE), the clinical component of the UCLA AIDS Institute, announced May 25, 1994, the commencement of a Phase I safety study of...

HIV may hinder killer cells.
June 20, 1994... Study HIV may be able to hamper the body's attack on the cells where it hides, which could help its infection persist, a study says. The study and a similar one with hepatitis B virus are the most direct demonstrations yet that some...

Company presents antiviral activity of compounds. (ProCyte Corp., copper-based compounds with antiviral activity)
June 20, 1994... Drug ProCyte Corporation, Kirkland, Washington, announced that Dr. Andrew Branca, principal scientist, presented data regarding ProCyte's recent discovery of several new copper-based compounds which have antiviral activity. He also...

FDA gives permission for AIDS IND studies. (Food and Drug Administration, acemannan)
June 20, 1994... Injectible Acemannan Carrington Laboratories Inc., Irving, Texas, announced that it has received permission from the U.S. Food & Drug Administration (FDA) to initiate a Phase I treatment plan study of human patients with AIDS using...

Alarming AIDS forecast in new WHO report. (World Health Organization)
June 20, 1994... International Thailand's AIDS nightmare can only get worse as the World Health Organization (WHO) predicts that HIV cases will increase up to eight times the current figure and AIDS cases will multiply up to tenfold by the year 2000. ...

Thailand begins AIDS trial. (vaccine)
June 20, 1994... Vaccine Trial The Thai Red Cross began testing a promising HIV vaccine on 30 HIV-free volunteers in the first of four planned clinical trials in developing countries. The vaccine is UBI-1, developed by United Biomedical Inc. ...

Study on sex released.
June 20, 1994... Teen Study Boys and girls are staying virgins longer than most adults think, according to a new report. The Alan Guttmacher Institute said that 62 percent of adults assume the average teen has sex before turning 16. But 70 percent...

New survey findings on teenage sexuality. ("Rolanda" show reveals results of Roper Starch Worldwide poll)
June 20, 1994... STD Raised under the specter of AIDS, America's teens are likely to have had sexual intercourse, more likely to use protection, wish they had waited longer before having intercourse, and report being very concerned about AIDS. ...

Elimination of female genital mutilation.
June 20, 1994... International Between 85 and 114 million girls and women have been subjected to female genital mutilation, according to a new report presented to the Forty-seventh World Health Assembly. Most of them live in 26 African countries, a few...

Biopharmaceutics announces revised HIV agreement. (Antisense Technologies Ltd., Central Research Institute for Chemistry of the Hungarian Academy of Sciences, development of antisense oligonucleotide)
June 20, 1994... Pharmaceutical Update Biopharmaceutics Inc., Bellport, New York, announced that its wholly-owned subsidiary, Antisense Technologies Ltd., ("Antisense") has reached a revised agreement with the Central Research Institute for Chemistry of...

Russian AIDS law needs review.
June 20, 1994... International A Russian parliamentary representative admitted that much talking needed to be done before a draft law aimed at preventing the spread of AIDS in Russia could be enforced. The proposed law empowers police and doctors to...

Highly conserved GAG peptide elicits CTL response. (cytotoxic T lymphocytes)
June 20, 1994... HIV Vaccines A synthetic peptide mimicking a B-cell epitope that is highly conserved between strains of HIV-1 induces specific CD8+ cytotoxic T lymphocytes (CTLs) in mice, Japanese researchers report. The apparent ability of this...

Racial differences in quality of care and outcome among patients with AIDS-related Pneumocystis carinii pneumonia. (Research Report)
June 20, 1994... AUTHORS: B. Cassileth, C.L. Bennett and L. Bastian. Duke University, Durham, North Carolina; and Veterans Administration Medical Center, Durham, North Carolina. According to an abstract submitted by the authors to the Thirtieth Annual...

Cytokine gene therapy for HIV-immunological effects of antigen-inducible expression of interleukin 7 in HIV-and tetanus-toxoid-specific T-cells. (Research Report)
June 20, 1994... AUTHORS: J.H. Kim, K.V. Sitz, S. Ratto, R.J. McLinden, K. Tencer, J.D. Mosca, D.L. Birx and R.R. Redfield. Walter Reed Army Institute of Research, Washington, D.C.; and Henry M. Jackson Foundation, Rockville, Maryland. According to an...

Zidovudine-induced gynecomastia in HIV-seropositive patients. (Research Report)
June 20, 1994... AUTHORS: L. Gilbert, R. Delapenha, W. Greaves and W. Frederick. Howard University, Washington, D.C. According to an abstract submitted by the authors to a joint meeting of the American Federation for Clinical Research, held April 29 -...

Prospective, multicenter, open-label, nonrandomized trial of paromomycin for cryptosporidiosis in AIDS. (Research Report)
June 20, 1994... AUTHORS: B. Ramratnam 1, T.P. Flanigan 1, C. Graeber 1, J. Hellinger 1, D. Smith 1 and J. Turner 1. 1Miriam Hospital, Providence, Rhode Island; 2Philadelphia Fight, Philadelphia, Pennsylvania; 3CRI New England, Boston, Massachusetts. ...

Gene therapy for HIV infection with nucleoside kinases. (Research Report)
June 20, 1994... AUTHORS: I. Lowy 1, M. Caruso 2, S.P. Goff 1, A. Bank 1 and D. Klatzmann 2. 1Columbia University, New York, New York; and 2Hopital de la Pitie-Salpetriere, Paris, France. According to an abstract submitted by the authors to a joint...

Priming of IL-2R-, CD4+ human blood T cells in vitro with the lymphocyte chemoattractant factor (LCF) for proliferation in response to IL-2. (interleukin 2) (Research Report)
June 20, 1994... AUTHORS: W.W. Cruikshank and D.M. Center. Boston University, School of Medicine, Boston, Massachusetts. According to an abstract submitted by the authors to a joint meeting of the American Federation for Clinical Research, held April 29...

GEM 91 - an antisense oligonucleotide as therapeutic agent for AIDS. (Research Report)
June 20, 1994... AUTHORS: S. Agrawal 1, J. Tang 1, D. Sun 2, R.C. Gallo 2 and J. Lisziewicz 2. 1Hybridon, Inc., Worcester, Massachusetts; and 2U.S. National Cancer Institute, Laboratory of Tumor Cell Biology, Bethesda, Maryland. According to an...

Potent inhibition of human immuodeficiency virus type 1 replication by an intracelluar anti-rev single chain antibody. (Research Report)
June 20, 1994... AUTHORS: L. Duan, O. Bagasra, M.A. Laughlin, J.W. Oakes and R.J. Pomerantz. Thomas Jefferson University, Dorrance H. Hamilton Laboratories, Philadelphia, Pennsylvania. According to an abstract submitted by the authors to a joint...

Persistent colonisation of potable water as a source of Mycobacterium avium infection in AIDS. (Adapted from Lancet, May 7, 1994) (Periodical Report) (Abstract)
June 20, 1994... SOURCE: Lancet, May 7, 1994;343(8906):1137-1141. According to the authors' abstract of an article published in the Lancet, "The source of Mycobacterium avium infection in AIDS has not been identified and it is not known whether most...

Inhibition of human immunodeficiency virus type I reverse transcriptase dimerization Using synthetic peptides derived from the connection domain. (Adapted from the Journal of Biological Chemistry, May 6, 1994) (Periodical Report) (Abstract)
June 20, 1994... SOURCE: Journal of Biological Chemistry, May 6, 1994;269(18):13080-13083. According to the authors' abstract of an article published in the Journal of Biological Chemistry, "Based on presently available information on the structure...

A 12-month study of the effects of oral zidovudine on neurodevelopmental functioning in a cohort of vertically Hiv-infected inner-city children. (Adapted from AIDS, May 1994) (Periodical Report) (Abstract)
June 20, 1994... SOURCE: AIDS, May 1994;8(5):635-639. According to the authors' abstract of an article published in AIDS, "Objective: To examine the effects of oral zidovudine on the neurodevelopmental functioning of HIV-infected children. Methods:...

A survey of occupational blood contact and HIV infection among traditional birth attendants in Rwanda. (Adapted from AIDS, May 1994) (Periodical Report) (Abstract)
June 20, 1994... SOURCE: AIDS, May 1994;8(5):701-704. According to the authors' abstract of an article published in AIDS, "Objective: To investigate the risk of occupationally acquired HIV infection among traditional birth attendants (TBA) in...

AIDS orphans in Kinshasa, Zaire - incidence and socioeconomic cosequences. (Adapted from AIDS, May 1994) (Periodical Report) (Abstract)
June 20, 1994... SOURCE: AIDS, May 1994;8(5):673-679. According to the authors' abstract of an article published in AIDS, "Objective: To determine the incidence, morbidity, mortality, and socioeconomic consequences of becoming an AIDS orphan (a...

Carnitine depletion in peripheral blood mononuclear cells from patients with AIDS - effect on oral L-carnitine. (Adapted from AIDS, May 1994) (Periodical Report) (Abstract)
June 20, 1994... SOURCE: AIDS, May 1994;8(5):655-660. According to the authors' abstract of an article published in AIDS, "Objective: Reduced levels of serum carnitines (3-hydroxy-4-N-trimethyl-ammonio-butanoate) are found in most patients treated...

Characterization of a human Kaposi's sarcoma cell line that induces angiogenic in animals. (Adapted from AIDS, May 1994) (Periodical Report) (Abstract)
June 20, 1994... SOURCE: AIDS, May 1994;8(5):575-581. According to the authors' abstract of an article published in AIDS, "Objective: To characterize a Kaposi's sarcoma (KS) cell line established from a tumor biopsy from the oral mucosa of an...

Comparison of the immune response to recombinant gp120 in humans and chimpanzees. (Adapted from AIDS, May 1994) (Periodical Report) (Abstract)
June 20, 1994... SOURCE: AIDS, May 1994;8(5):591-601. According to the authors' abstract of an article published in AIDS, "Objective: To assess similarities and differences in antibody responses to recombinant (r) HIV-1-IIIB gp120 in chimpanzees,...

Feline immunodeficiency virus can be experimentally transmitted via milk during acute maternal infection. (Adapted from the Journal of Virology, May 1994) (Periodical Report) (Abstract)
June 20, 1994... SOURCE: Journal of Virology, May 1994;68(5):3380-3385. According to the authors' abstract of an article published in the Journal of Virology, "Postnatal transmission of feline immunodeficiency virus (FIV) in neonates nursed by...

Full-scale HIV vaccine trial delayed.
June 27, 1994... HIV Vaccine The U.S.'s top AIDS researcher decided against expanding current research on two candidate vaccines into full-scale trials to test efficacy. Dr. Anthony S. Fauci unexpectedly issued his decision immediately following...

Watchdog group alleges manipulation of HIV vaccine trial data. (Public Citizen's Health Research Group)
June 27, 1994... Industry News A well-known military researcher working on an experimental HIV vaccine engaged in "a systematic pattern of data manipulation, inappropriate statistical analyses and misleading data presentation," according to the consumer...

Infected Indians protest "vampire project." (unauthorized experiments with blood samples from Guaymi Indians of Panama)
June 27, 1994... Controversy An international effort to study a mysterious retrovirus has put Panama's Guaymi Indians on a collision course with scientific research. Thousands of Guaymis infected with the HTLV-II virus gave blood samples to local...

New technique refines in vitro evolution of synthetic HIV antibodies. (complementarity-determining region walking)
June 27, 1994... Laboratory Methods A new technique can improve the affinity and potency of synthetic antibodies that neutralize HIV while broadening their strain reactivity, a U.S. research team reports. The researchers, Carlos F. Barbas III of...

Psoralen derivatives maintain platelet function.
June 27, 1994... Virus Inactivation Cryopharm Corporation, Pasadena, California, recently announced that a novel class of components known as psoralen derivatives, which inactivate bloodborne viruses, are able to maintain the function of blood platelets,...

Saliva of bloodsucking vectors inhibit immune cells. (parasite carriers)
June 27, 1994... Parasite Carriers Understanding more about substances in the saliva of ticks, mosquitoes and other bloodsucking vectors may lead to development of vaccines, reported Kurt Kleiner, a writer based in Baltimore, Maryland. Vectors such...

Mitogen stimulation can reactivate HBV DNA sequences. (hepatitis B virus)
June 27, 1994... Hepatitis B Virus Spanish researchers suggested that the human lymphoid system may be a reservoir of hepatitis B virus (HBV) DNA sequences that, in some HIV-1-infected individuals, can be reactivated by mitogen stimulation. This...

Tuberculosis underestimated in HIV wasting. (African HIV wasting syndrome, or slim disease)
June 27, 1994... TB/HIV Tuberculosis (TB) causes far more cases of African HIV wasting syndrome than previously thought, according to a new study. HIV wasting syndrome had been associated with an intestinal parasite, but this study shows that TB is...

Preventive therapy works well in HIV+. (preventive tuberculosis therapy)
June 27, 1994... ALA/ATS Preventive tuberculosis (TB) therapy can work well in the human immunodeficiency virus (HIV)-positive population, according to a Boston Department of Health and Hospitals report. "We were very encouraged by our experience...

Interaction between TB and HIV prominent in Nigeria.
June 27, 1994... Epidemiology A review of the prevalence of human immunodeficiency virus (HIV) antibodies in tuberculosis (TB) patients in Lagos, Nigeria, points to some level of interaction between TB and HIV infections. An association between HIV...

Ocular fundus exams needed in those with TB/AIDS. (diagnosing tuberculosis choroiditis)
June 27, 1994... TB Choroiditis Ocular fundus examination may be necessary to detect tuberculous choroiditis in patients with tuberculosis (TB) and AIDS, even when the patient has no ocular symptoms. Clinicians from a Spanish research center...

AMA urges HIV counseling for pregnant women. (American Medical Association)
June 27, 1994... Pregnancy The American Medical Association (AMA) asked doctors to counsel pregnant women who are at a high risk for HIV infection to undergo testing and possibly antiretroviral therapy with zidovidine (AZT). At its annual meeting,...

Cell Genesys announces IND filing for anti-HIV therapy. (investigational new drug application for anti-HIV T-cell therapy)
June 27, 1994... Clinical Trial Cell Genesys Inc., Foster City, California, announced that an Investigational New Drug (IND) application has been filed with the U.S. Food and Drug Administration (FDA) for the initial human clinical trial of the company's...

Biomune announces filing of IND. (Biomune Systems Inc.; investigational new drug application for Immuno-C)
June 27, 1994... New Drug Biomune Systems Inc. announced its filing of an Investigative New Drug Application (IND) on the company's drug, Immuno-C. The written material which is the basis of the IND submission is a compilation of 15 years of work...

HemaCare reports on regulatory status of Immupath.
June 27, 1994... Treatment News HemaCare Corporation reported on the progress of the Phase III Investigational New Drug (IND) application to test Immupath, a potential treatment for HIV/AIDS, submitted to the U.S. Food and Drug Administration (FDA). ...

Deficiencies can change viruses, making them more deadly. (nutritional deficiencies)
June 27, 1994... Nutrition For the first time, scientists at the University of North Carolina at Chapel Hill (UNC-CH) School of Medicine have discovered that a normally harmless human virus changes and becomes more dangerous after infecting an animal...

Formula creates competition in medical industry. (Nutrition Medical's L-Emental generic nutrition formula)
June 27, 1994... Nutrition Nutrition Medical, Minneapolis, Minnesota, now offers the first generic substitute for brand name therapeutic nutritional formulas for use in medical settings. L-Emental, an elemental formula designed to meet the total...