AIDS Weekly articles from June 1991

AIDS Weekly archives from June 1991

Sexually transmitted diseases and high-risk sexual behavior may speed progression of HIV-1 infection to AIDS. (Multicenter AIDS Cohort Study report) (VII International Conference on AIDS)
June 24, 1991... VII International Conference on AIDS Sexually transmitted diseases and frequent anal receptive intercourse, both before and after seroconversion, are associated with rapid progression of HIV-1 infection to AIDS in homosexual men,...

Dana-Farber researchers report new progress against AIDS. (Dana-Farber Cancer Institute research of Langerhans cells and how they may promote transmission of disease) (VII International Conference on AIDS)
June 24, 1991... VII International Conference on AIDS Researchers at Harvard's Dana-Farber Cancer Institute in the United States announced new scientific advances in understanding HIV and in finding potential new ways to inhibit its ability to infect...

Differences in molecular structure of non-Hodgkins lymphoma in AIDS patients may predict survival time. (University of California, San Francisco research) (VII International Conference on AIDS)
June 24, 1991... VII International Conference on AIDS Survival rates and clinical behavior of AIDS patients with non*Hodgkins lymphoma, one of the serious and usually fatal diseases affecting AIDS patients, may be determined by the molecular...

Zagury reports on vaccine research. (Daniel Zagury) (VII International Conference on AIDS)
June 24, 1991... VII International Conference on AIDS In one of the best attended sessions of the VII International Conference on AIDS the controversial French researcher Daniel Zagury presented preliminary results from his work on an AIDS vaccine to...

Gallo optimistic about research prospects. (Robert Gallo; AIDS research) (VII International Conference on AIDS)
June 24, 1991... VII International Conference on AIDS Robert Gallo of the U.S. National Cancer Institute (NCI) is optimistic about finding new treatments for AIDS, speculating that gene therapy and a mutant soil bacterium may eventually prove effective....

CD8 lymphocytes stop HIV growth by blocking viral RNA. (University of California, San Francisco) (VII International Conference on AIDS)
June 24, 1991... VII International Conference on AIDS University of California at San Francisco (UCSF) researchers have reported that immune system cells called CD8 lymphocytes can stop HIV replication by blocking production of RNA, the viral genetic...

Research finds HIV can be "expressed" during early development in mice. (University of California, San Francisco; cell changes evident in embryos) (VII International Conference on AIDS)
June 24, 1991... VII International Conference on AIDS A researcher at the University of California at San Francisco (UCSF) has found that the human immunodeficiency virus (HIV) is capable of "expressing" itself in cells of the early embryo in a mouse...

AZT may be of benefit in cases of Hepatitis C. (Tiziana Garofano, Pugliese Hospital, Catanzaro, Italy research) (VII International Conference on AIDS)
June 24, 1991... VII International Conference on AIDS AIDS-infected patients suffering from hepatitis C may benefit from treatment with AZT, an AIDS drug previously denied to them. A study presented at the VII International Conference on AIDS says...

UCSF expert is first recipient of international award. (University of California, San Francisco's Paul Volberding; Lottare, Informe, Formare, Educare International prize) (VII International Conference on AIDS)
June 24, 1991... VII International Conference on AIDS Paul A. Volberding, M.D., University of California at San Francisco (UCSF) professor of medicine and director of the AIDS Program at San Francisco General Hospital, was named the first recipient of...

HIV may have peaked in west, but on the rise elsewhere. (World Health Organization report; United States and western Europe) (VII International Conference on AIDS)
June 24, 1991... VII International Conference on AIDS The spread of HIV in the United States and western Europe may have peaked in the mid-1980s, a World Health Organization official said. But Dr. James Chin cautioned that the virus is expected to...

AIDS cost to U.S. to double by 1994. (VII International Conference on AIDS)
June 24, 1991... VII International Conference on AIDS Fred Hellinger, Director of the Division of Cost and Financing of the U.S. Department of Health and Human Services (HHS) has told the VII International Conference on AIDS that the yearly cost of...

The pharmaceutical industry commits itself to working with WHO. (World Health Organization meeting on AIDS research) (Switzerland)
June 24, 1991... Switzerland At a landmark meeting cosponsored by the World Health Organization (WHO) Global Program on AIDS and the United Nations Development Program (UNDP), representatives of 18 major research*based pharmaceutical companies...

Proper controls of laboratory tests critical to evaluate behavior of HIV. (Los Alamos National Laboratory)
June 24, 1991... Los Alamos National Laboratory Two important conditions must be controlled in laboratory experiments with HIV before test-tube results can provide reliable evaluations of potential therapies or vaccines, said two Los Alamos National...

Experimental vaccine stabilizes T-cell count. (AIDS vaccine) (Walter Reed Army Institute of Research)
June 24, 1991... Walter Reed Army Institute of Research Researchers reported in the New England Journal of Medicine that levels of T cells have remained stable during more than two years of treatment in some of the 30 people receiving an experimental,...

HIV-1 viral sequences differ in blood and brain. (Northwestern University Medical School research)
June 24, 1991... Italy HIV-1 varies not only among patients but also between blood and brain tissue in the same individual, a finding that has important implications for development of an AIDS vaccine. "HIV-1 is a more versatile virus than we...

HTLV-1 and HTLV-II found more common among blood donors. (Abbott Laboratories)
June 24, 1991... Washington, D.C. Two cousins of HIV appear more common among U.S. blood donors than previously thought, researchers have reported. A new study involving 480,000 blood donors in five U.S. urban areas found 4.3 of every 10,000...

Lack of funding leaves U.S. cities unable to cope with epidemic. (spread of AIDS) (U.S. Conference of Mayors)
June 24, 1991... U.S. Conference of Mayors The mayors of America's major cities have concluded that they will be unable to cope with the steady growth of AIDS cases because of a lack of money. The 30-page report was released by the U.S. Conference...

Redefining AIDS could double number of Americans classified as having disease. (Centers for Disease Control)
June 24, 1991... U.S. CDC Officials of the U.S. Centers for Disease Control (CDC) said that they are considering changing the definition of AIDS, a move that could double the number of HIV-infected Americans officially classified as having the disease....

Predictors of Aids rehospitalization in San Francisco (SF). (Research Report)
June 24, 1991... AUTHORS: S.W. Chang, J. Arthur, A. Hirozawa, D. Franks, G. Lemp. Department of Public Health, San Francisco, California. According to an abstract submitted by the authors to the VII International Conference on AIDS, Florence, Italy,...

Impact of HIV infection on mortality and accuracy of AIDS reporting on death certificates. (Research Report)
June 24, 1991... AUTHORS: N. Hessol, S. Buchbinder, D. Colbert, S. Scheer, R. Underwood, L. Barnhart, P. O'Malley, L. Doll, A. Lifson. AIDS Office, San Francisco Health Dept., San Francisco, California; Division of HIV/AIDS, Centers for Disease Control,...

Prevalence of HIV-1 among homosexual and bisexual men in the San Francisco Bay Area: evidence of infection among young gay men. (Research Report)
June 24, 1991... AUTHORS: T.A. Kellogg, M.J. Wilson, G.F. Lemp, S.R. Hernandez, J. Reardon, J. Ruiz, M. Elcock, G. Bolan, B. Obata. San Francisco Department of Public Health, San Francisco, California; California Department of Health Services, Sacramento,...

Early intervention for HIV-infection: a gap between theory and practice. (Research Report)
June 24, 1991... AUTHORS: M.H. Katz, A.B. Bindman, D. Keane, A.K. Chan. University of California at San Francisco, San Francisco, California. According to an abstract submitted by the authors to the VII International Conference on AIDS, Florence,...

Syringe exchange (SE) in San Francisco: preliminary findings. (statistics on drug abusers who take advantage of needle-exchange programs) (Research Report)
June 24, 1991... AUTHORS: J. Watters, Y. Cheng, and Prevention Point Research Group. University of California at San Francisco, San Francisco, and at Berkeley, Berkeley, California. According to an abstract submitted by the authors to the VII...

What about condoms?: black, Hispanic, and white views from a population-based sample. (Research Report)
June 24, 1991... AUTHORS: S.M. Kegeles, J. Catania, J. Peterson, B. Marin, M. Fullilove, S. Hulley, T. Coates. University of California at San Francisco Center for AIDS Prevention Studies (CAPS), San Francisco, California. According to an abstract...

Does germ-line integration of HIV-1 result in expression during development? (fetal development) (Research Report)
June 24, 1991... AUTHORS: P.G. Calarco. and K.J. Whitmer. Department of Anatomy, University of California at San Francisco, and Department of Biology, San Francisco State, San Francisco, California. According to an abstract submitted by the authors to...

CD8+ lymphocytes from HIV-1 seropositive individuals block HIV replication in CD4+ lymphocytes by inhibiting viral RNA synthesis. (Research Report)
June 24, 1991... AUTHORS: C. Mackewicz, H. Legg, H. Ortega, and J.A. Levy. University of California, School of Medicine, San Francisco, California. According to an abstract submitted by the authors to the VII International Conference on AIDS, Florence,...

Molecular predictors of survival in HIV associated non-Hodgkin's lymphoma. (Research Report)
June 24, 1991... AUTHORS: L.D. Kaplan, B. Shiramizu, J.O. Kahn, B. Herndier, T. Meeker, D. Northfelt, and M. McGrath. University of California at San Francisco, San Francisco, California. According to an abstract submitted by the authors to the VII...

Anti-HIV activity of CD4-Pseudomonas exotoxin on infected primary human lymphocytes and monocytes/macrophages. (Periodical Report)
June 24, 1991... SOURCE: The Journal of Infectious Diseases, April 1991; 163(4):703-709. The hybrid molecule combining recombinant soluble CD4 with the active portion of Pseudomonas aeruginosa exotoxin A - CD4(178)-PE40 - inhibits the spread of HIV in...

Systemic treatment of AIDS-related Kaposi's sarcoma: results of a randomized trial. (Periodical Report)
June 24, 1991... SOURCE: The American Journal of Medicine, April 1991;90(4):427-433. Low-dose combination chemotherapy for extensive AIDS -associated Kaposi's sarcoma (KS) with Adriamycin (doxorubicin), bleomycin, and vincristine (ABV therapy) yields...

Inhibition of heterologous strains of HIV by antisense RNA; and, Antisense RNA to treat HIV infections. (University of Oxford report) (Periodical Report)
June 24, 1991... SOURCE: AIDS, March 1991;5(3):145-151 and 225-226. Although antisense RNAs can inhibit different strains of HIV*1, the degree of inhibition varies widely by the type of cell infected by the virus, British researchers report. ...

Long-term human immunodeficiency virus in asymptomatic homosexual and bisexual men with normal CD4+ lymphocyte counts: immunologic and virologic characteristics. (Periodical Reports)
June 24, 1991... SOURCE: The Journal of Infectious Diseases, May 1991;163(5):959-965. A group of men who remain asymptomatic with normal -range CD4+ cell counts despite having been infected with HIV for a median 9.1 years have significantly higher...

Small viral variation may have large impact on effectiveness of antibodies against HIV. (VII International Conference on AIDS )
June 17, 1991... University of California at San Francisco (UCSF) researchers have found that even small differences in the protein coats of strains of HIV may determine whether an anti-HIV antibody prevents infection by the virus, has no effect or actually...

Study examines high-risk taking among young gay and bisexual men. (VII International Conference on AIDS)
June 17, 1991... More than one-third of young gay and bisexual men in a University of California at San Francisco (USCF) study have engaged in high-risk sex, a finding that alarms AIDS prevention researchers (see also Research Report, this issue page 20). ...

Women with HIV have increased risk of cervical abnormalities. (VII International Conference on AIDS)
June 17, 1991... A study of women infected with HIV has found that 44 percent were also infected with human papillomavirus (HPV), University of California at San Francisco (UCSF) researchers reported in Florence, Italy, at the VII International Conference on...

Study shows homeless are at risk of HIV. (VII International Conference on AIDS)
June 17, 1991... One in ten adult homeless persons in San Francisco are now infected with the human immunodeficiency virus (HIV), according to a study based at the University of California at San Francisco (UCSF) (see also Research Report, this issue, page...

Budget cut in AIDS funds threatened over size of contingent to Italy. (VII International Conference on AIDS) (Washington, D.C.)
June 17, 1991... U.S Congressional leaders have threatened to reduce federal funding for AIDS unless the Department of Health and Human Services (HHS) cuts the number of scientists scheduled to attend the VII International Conference on AIDS from 300 to 100....

Multi-disease vaccine breakthrough. (Pittsburgh, Pennsylvania)
June 17, 1991... Scientists in the department of biological sciences at the University of Pittsburgh, in collaboration with scientists in New York and Maryland, have reported a major step towards the development of a "multi-disease" vaccine that could, with a...

Therapy kills infected cells in test tube, spares healthy ones. (University of California, San Francisco)
June 17, 1991... University of California, San Francisco, (UCSF) researchers have designed and AIDS therapy that marshals all the body's killer T cells to attack virus-infected cells, while sparing healthy, uninfected cells. The therapy works because...

New model proposed for pathophysiology of HIV. (Calypte Biomedical Corp.)
June 17, 1991... An article published in Biotech Forum Europe (Vol. 8, No. 4), an international journal of biotechnology, proposes a new model for the pathophysiology of HIV that has significant public health implications. It is also implicitly predictive of...

New assay helps researchers. (SyStemix Inc.)
June 17, 1991... Researchers at SyStemix, Inc. have developed a small animal model (the SCID-hu mouse) which contains a human blood-forming system. Previously, the human lymphoid organs of this animal model have been shown to be permissive for infection wi...

Administration HIV immigration policy blasted. (San Francisco AIDS Foundation)
June 17, 1991... The San Francisco AIDS Foundation (SFAF) on May 29, 1991, joined the international community in condemning the continuation of discriminatory HIV immigration policies and called on the Bus Administration to support Health and Human Services...

Letter calls for expanded case definition of HIV disease. (American Medical Association) (transcript)
June 17, 1991... In a letter to William Roper, M.D., director of the Centers for Disease Control (CDC) dated May 29, 1991, M. Roy Schwarz, M.D., senior vice president of medical education and science of the American Medical Association (AMA), asks that the...

HIV insurance policy for physicians introduced. (American Medical Association)
June 17, 1991... The American Medical Association (AMA) announced that AMA Insurance Agency Inc. will market an insurance plan to cover physicians contracting HIV through occupational exposure. Traditional forms of medical, disability and life insurance...

Garamendi proposes comprehensive agenda for reform of health insurance. (California Insurance Commissioner John Garamendi) (Los Angeles, California)
June 17, 1991... Vowing to mend a health care system that permits insurers to cancer coverage or triple rates for sick patients, leaves millions of Californians uninsured and consumers an increasingly share of everyone's disposable income, California...

Increased T-cell count attributed to "cocktail" drug. (BC-IL) (CEL-SCI Corp.)
June 17, 1991... Major laboratory test results indicating a breakthrough in the battle against the aging process have been announced by CEL-SCI Corporation of Alexandria. Administration of CEL-SCI's natural lymphokine "cocktail" (BC-IL) significantly...

HIV disease progression and the impact of prophylactic therapies (PROP) in the San Francisco City Clinic Cohort (SFCCC): a 13-year follow-up. (Research Report)
June 17, 1991... According to an abstract submitted by the authors to the VII International Conference on AIDS, Florence, Italy, June 16-21,1991: "Objective: To determine time from estimated HIV seroconversion (SC) to AIDS and death and to assess the impact...

Improved survival for persons with AIDS in San Francisco. (Research Report)
June 17, 1991... According to an abstract submitted by the authors to the VII International Conference on AIDS, Florence, Italy, June 16-21, 1991: "Objective: To examine survival trends for persons with AIDS in San Francisco and to determine the effect of...

Survival trends among women with AIDS in San Francisco. (Research Report)
June 17, 1991... According to an abstract submitted by the authors to the VII International Conference on AIDS, Florence, Italy, June 16-21, 1991: "Objective: To characterized trends in the length of survival among women with AIDS reported to SFDPH between...

Homelessness and HIV infection: a population based study. (San Francisco, California) (Research Report)
June 17, 1991... According to an abstract submitted by the authors to the VII International Conference on AIDS, Florence, Italy, June 16-21, 1991: "Objective: To determine the HIV seroprevalence rates and risk factors for HIV infection among the adult...

V3 epitopes can mediate antibody neutralization and enhancement of HIV-1 infection. (Research Report)
June 17, 1991... According to an abstract submitted by the authors to the VII International Conference on AIDS, Florence, Italy, June 16-21, 1991: "Objective: To investigate the mechanism of strain-specific antibody neutralization and enhancement of infection...

Understanding the high rates of HIV risk-taking among young gay and bisexual men: the Young Men's Survey. (Research Report)
June 17, 1991... According to an abstract presented by the authors to the VII International Conference on AIDS, Florence, Italy, June 16-21, 1991: "Objective: To examine factors associated with unsafe sex among young gay and bisexual men and generate ideas...

Association of HIV-1, cervical/anal cytological abnormalities and human papillomavirus in female injection drug users in San Francisco, California, U.S.A. (Research Report)
June 17, 1991... According to an abstract submitted by the authors to the VII International Conference on AIDS, Florence, Italy, June 16-21, 1991: "Objective: To examine the relationship between HIV-1 serostatus, cervical or anal cytological abnormalities,...

Mycobacterium kansasii: a cause of treatable pulmonary disease associated with advanced immunodeficiency virus infection. (Periodical Report)
June 17, 1991... HIV-associated pulmonary disease due to Mycobacterium kansasii (M. kansasii) (is more common than previously thought and - contrary to previous reports - responds to antituberculosis therapy, report Beth Levine and Richard E. Chaisson of...

Altered production of tumor necrosis factors alpha and beta and interferon gamma by HIV-infected individuals. (Periodical Report)
June 17, 1991... Altered production of cytokines occurs early in the course of HIV infection and apparently contributes to AIDS pathogenesis, a British study shows. University College and Middlesex School of Medicine researcher A. Vyakarnam and...

Discrepancies in AIDS virus data. (Periodical Report)
June 17, 1991... French researchers report that cultures from which HIV was first isolated contained not one, but two viruses. Because of widely reported discrepancies in the biological behavior of the early HIV isolate known as JBB-Lav, Jean-Claude...

Zidovudine (AZT) for treatment of patients infected with human immunodeficiency virus type 1: an evaluation of effectiveness in clinical practice. (Periodical Report)
June 17, 1991... Reductions in AZT dosage due to toxicity do not necessarily indicate adverse outcomes for patients, an observational cohort study indicates. Yale University researchers Eve R. Colson and colleagues followed 86 patients with AIDS or ARC...

The HIV/AIDS epidemic: the first 10 years. (Periodical Report)
June 17, 1991... "On June 5, 1981, the first cases of an illness subsequently defined as acquired immunodeficiency syndrome (AIDS) were reported by healthcare providers in California and CDC. As of May 31, 1991, state and local health departments had reported...

Current trends update: acquired immunodeficiency syndrome - United States, 1981-1990. (Periodical Report)
June 17, 1991... "In 1981, 189 cases of acquired immunodeficiency syndrome (AIDS), a newly recognized condition, were reported to CDC from 15 states and the District of Columbia; 76 percent of cases were reported from New York and California. Ninety-seven...

International course in surveillance and applied epidemiology for HIV and AIDS. (Periodical Report)
June 17, 1991... "Centers for Disease Control, the Emory University School of Public Health, the Global Program on AIDS and the Pan American Health Organization of the World Health Organization, the Fogarty International Center of the U.S. National Institutes...

Eight thousand scientists in Florence, Italy, June 16-21. (VII International Conference on AIDS)
June 10, 1991... VII International Conference on AIDS Over eight thousand scientists and researchers are gathering in Florence, Italy, from June 16-21, 1991, for the VII International Conference on AIDS, "a scientific event that promises to be rich in...

Preview of VII International Conference on AIDS. (Florence, Italy)
June 10, 1991... Florence, Italy Limited by space constraints to 8,000 attendees, this year's AIDS conference in Florence, Italy, was filled two months prior to its June 16 opening. Co-sponsors Giovanni B. Rossi, director of the Laboratory of...

Gallo acknowledges French actually discovered HIV. (Robert C. Gallo) (National Cancer Institute)
June 10, 1991... U.S. NCI According to an Associated Press story published May 30, 1991, the Chicago Tribune reports that Robert C. Gallo, the U.S. researcher credited as the co-discoverer of HIV in 1984, now acknowledges that French scientists at the...

University threatens to cancel VIII International Conference on AIDS. (Harvard University)
June 10, 1991... Harvard University Officials at Harvard University have threatened to cancel the 1992 VIII International Conference on AIDS unless the Bush administration lifts its current ban on travel and immigration by individuals with HIV. The ban...

Burroughs Wellcome's AZT patent questioned by federal government. (zidovudine) (National Cancer Institute)
June 10, 1991... U.S. NCI Dr. Bernadine Healy, director of the U.S. National Institutes of Health (NIH) said that the U.S. National Cancer Institute (NCI) should be named co-inventor of the anti-AIDS drug AZT (zidovudine). "NIH believes that...

New drug applications listed. (Food & Drug Administration )
June 10, 1991... U.S. FDA (For complete information on AIDS treatments, refer to the monthly directory service published by AIDS WEEKLY titled DAITA: Current AIDS Therapies, formerly called Directory of Antiviral and Immunomodulatory Therapies for AIDS...

Company lifts hold on human testing of AIDS drug. (RO 24-7429) (Hoffmann-La Roche Inc.)
June 10, 1991... Hoffmann-La Roche Hoffman-La Roche, Inc., has lifted a hold on human tests of an AIDS drug, currently labeled RO 24-7429, and is actively seeking a licensing arrangement with a partner. "We did place a hold on one AIDS drug," said...

State AIDS Clinical Trials Testing Fund award goes to Chiron. (California)
June 10, 1991... California State Health Director Kenneth W. Kizer, M.D., M.P.H., announced the selection of Chiron Corporation of Emeryville, Calif., as the successful candidate to receive support through the California AIDS Clinical Trials Testing...

Ajinomoto Company plans clinical trials of anti-AIDS drug curdlan sulfate (CRDS). (Japan)
June 10, 1991... Japan Ajinomoto Company Inc., Tokyo, Japan, said it plans to start clinical tests of its anti-AIDS drug curdlan sulfate by the end of 1991. Curdlan sulfate, also called CRDS, is a sulfated polysaccharide and has been reported to...

Tobacco research focusing on anti-AIDS drug Compound Q. (North Carolina State University)
June 10, 1991... North Carolina State University Tobacco research at North Carolina State University, Raleigh, North Carolina, is focusing on development of the anti-AIDS drug Compound Q. "It could revolutionize the way we look at tobacco," said...

Letter of intent to purchase Applied bioTechnology. (Oncogene Science Inc.)
June 10, 1991... Oncogene Science Oncogene Science, Inc. announced it has entered into an agreement in principle to acquire Applied bioTechnology, Inc., a Cambridge, Massachusetts-based privately held biotechnology firm primarily focused on the...

Proposed cuts in city AIDS budget risk federal funding. (Philadelphia, Pennsylvania)
June 10, 1991... Philadelphia A proposed cut of $1.7 million in Philadelphia, Pa., AIDS services will jeopardize at least $2.3 million in federal funds and will compound the AIDS tragedy in the city, said Richard Scott, chair of the Philadelphia AIDS...

State health director criticizes call for routine AIDS testing. (Kenneth W. Kizer) (California)
June 10, 1991... California California State Health Director Kenneth W. Kizer, M.D., M.P.H., expressed concern over an editorial that appeared in the New England Journal of Medicine which advocates routine AIDS testing of hospital patients, pregnant...

Health and Welfare Ministry reports AIDS and HIV case totals. (Japan)
June 10, 1991... Japan Japan's Health and Welfare Ministry reports that a total of 1,656 Japanese have tested positive for HIV, and another 378 are classified as AIDS patients. Of the 17 new HIV positive cases reported in March and April, nine...

Government reports 300,000 are HIV infected. (Thailand)
June 10, 1991... Thailand Nearly 300,000 Thais have contracted HIV, senior Thai government official Meechai Veeravidhaya, minister attached to the Prime Minister's Office, told reporters in a televised interview. According to a recent survey,...

Community weighs condom warnings. (effectiveness of latex vs. 'natural' lambskin) (Santa Barbara, California)
June 10, 1991... Santa Barbara, California The Santa Barbara County Board of Supervisors met May 21, 1991, to vote on a law that would oblige merchants to warn customers that some condoms are more effective than others in protecting against HIV. ...

Phase I-II trial of dideoxyinosine with interferon-alpha in the treatment of HIV infection. (Research Report)
June 10, 1991... ARTHORS: J.A. Kovacs, C. Boenning, R.T. Davey, R.J. Walker, M.A. Polis, J. Falloon, G. Galetto, E. Seidel, V. Davey, J. Metcalf, A.S. Fauci, H. Masur and H.C. Lane. NIAID and CCMD, U.S. National Institutes of Health, Bethesda, Md. ...

Beta-carotene therapy in human immunodeficiency virus infection. (Research Report)
June 10, 1991... AUTHORS: G.O. Coodley. Division of General Internal Medicine, Oregon Health Sciences University, Portland, Ore. According to the abstract submitted by the authors to the annual meeting of the Association of American Physicians, the...

High titers of cytopathic virus in plasma of patients with symptomatic primary human immunodeficiency virus type-1 infection. (Research Report)
June 10, 1991... AUTHORS: S.J. Clark, M.S. Saag, W.D. Decker, S. Campbell-Hill, J.L. Roberson, J.C. Kappes, P.J. Veldkamp, B.H. Hahn and G.M. Shaw. Departments of Medicine and Microbiology, University of Alabama at Birmingham. According to the...

Zidovudine and the natural history of the acquired immunodeficiency syndrome. (Periodical Report)
June 10, 1991... SOURCE: The New England Journal of Medicine, May 16, 1991;324(20):1412-1416. Zidovudine (AZT) therapy is the factor most strongly associated with improved survival among people with AIDS, a population-based study indicates. ...

A multicenter trial of oral zidovudine in children with advanced human immunodeficiency virus disease. (Periodical Report)
June 10, 1991... SOURCE: The New England Journal of Medicine, April 11, 1991;324(15):1018-1025. Relatively high doses of zidovudine (AZT) can be tolerated by children with therapeutic effects equivalent to those seen in adults, a NIAID multicenter...

Failure of prophylactic zidovudine after suicidal self-inoculation of HIV-infected blood. (Periodical Report)
June 10, 1991... SOURCE: The New England Journal of Medicine, April 11, 1991;324(15):1062. Zidovudine (AZT) administered to a woman two hours after she inoculated herself with blood from a terminal AIDS patient failed to prevent HIV infection. ...

New anti-PCP drug safe and effective, early trials show. (Pneumocystis carinii pneumonia, 566C80) (Burroughs Wellcome Co.)
June 3, 1991... Burroughs Wellcome A new drug for the treatment of Pneumocystis carinii pneumonia (PCP) is highly effective and amazingly well tolerated, early Phase I/II clinical trials indicate (see also Research Report, this issue, page 15 and...

AZT healthcare doubles survival time for AIDS patients. (zidovudine) (Johns Hopkins University)
June 3, 1991... Johns Hopkins In the first study of its kind, scientists at Johns Hopkins and the Maryland Department of Health and Mental Hygiene's AIDS Administration have shown that AIDS patients treated with the anti-AIDS drug zidovudine (AZT)...

Barr Laboratories sued for AZT patent infringement. (zidovudine) (Burroughs Wellcome Co.)
June 3, 1991... Burroughs Wellcome Burroughs Wellcome Company, Research Triangle Park, North Carolina, filed a complaint for Patent Infringement in the U.S. District Court, Eastern District of North Carolina, against Barr Laboratories Inc. of New...