AIDS Weekly articles from July 1995, page 2

AIDS Weekly archives from July 1995

Bronchogenic carcinoma in HIV positive patients.(Research Report)
July 10, 1995... According to an abstract submitted by the authors to the 1995 International Conference of the American Thoracic Society, held May 20-24, 1995, in Seattle, Washington, "OBJECTIVE: To compare the epidemiology of bronchogenic carcinoma (BC) in...

Immune complexes in HIV and HBV infections.(Research Report)
July 10, 1995... According to an abstract submitted by the authors to The Year of Louis Pasteur International Symposia entitled Etiology and Pathogenesis of Infectious Diseases, held April 10-13, 1995, in Dakar, Senegal, "Circulating immune complexes are part...

Virological and immunological study of patients coinfected with human immunodeficiency and Hepatitis C viruses.(Research Report)
July 10, 1995... According to an abstract submitted by the authors to The Year of Louis Pasteur International Symposia entitled Etiology and Pathogenesis of Infectious Diseases, held April 10-13, 1995, in Dakar, Senegal, "Several clinical observations suggest...

Cell targeting and uptake of antisense oligonucleotides encapsulated in immunoliposomes.(Research Report)
July 10, 1995... According to an abstract submitted by the authors to the NATO Advanced Studies Institute symposium entitled Targeting of Drugs: Strategies for Oligonucleotide and Gene Delivery in Therapy, held June 24 - July 5, 1995, in Cape Sounion Beach,...

Retrovirus mediated gene transfer for anti-retroviral (HIV-1) therapy.(Research Report)
July 10, 1995... According to an abstract submitted by the author to the NATO Advanced Studies Institute symposium entitled Targeting of Drugs: Strategies for Oligonucleotide and Gene Delivery in Therapy, held June 24 - July 5, 1995, in Cape Sounion Beach,...

Effects of a community outreach program in HIV risk behaviors among injection drug users in San Juan, Puerto Rico: an analysis of trends.(reprinted from AIDS Education and Prevention, June 1995)(Periodical Report)(Abstract)
July 10, 1995... According to the authors' abstract of an article published in AIDS Education and Prevention, "This report assesses the effects of a community outreach program in reducing HIV risk behaviors among injection drug users (IDUs) in San Juan, Puerto...

HIV-1 p17 synthetic peptide vaccine HGP-30: induction ofimmune response in human subjects and preliminary evidence of protection against HIV challenge in SCID mice.(reprinted from Cellular and Molecular Biology, May 1995)(Periodical Report)(Abstract)
July 10, 1995... According to the authors' abstract of an article published in Cellular and Molecular Biology, "An HIV-1 p17 subunit vaccine, HGP-30, was evaluated in 38 HIV-1 seronegative individuals in Phase I clinical trials in U.K. and U.S.A. The vaccine...

Inhibition of HIV type 1 infection of mononuclear phagocytes by anti-CD44 antibodies.(Reprinted from AIDS Research and Human Retroviruses, May 1995)(Periodical Report)(Abstract)
July 10, 1995... According to the authors' abstract of an article published in AIDS Research and Human Retroviruses, "Cellular CD4 is the primary membrane molecule that binds HIV-1 through interaction with viral gp120. Membrane glycolipids and cell adhesion...

HIV-2-specific cytotoxic T-lymphocyte activity is inversely related to proviral load.(reprinted from AIDS, June 1995)(Periodical Report)(Abstract)
July 10, 1995... According to the authors' abstract of an article published in AIDS, "OBJECTIVES: To characterize HIV-specific cytotoxic T-lymphocyte (CTL) activities in HIV-2-infected individuals and to relate these to HIV-2 proviral load. METHODS:...

Characterization of V3 loop-binding protein(s) of Molt-4 and U937 cells.(reprinted from AIDS Research and Human Retroviruses, May 1995)(Periodical Report)(Abstract)
July 10, 1995... According to the authors' abstract of an article published in AIDS Research and Human Retroviruses, "The V3 loop in gp120 of human immunodeficiency virus type 1 (HIV-1) is known as a principal neutralizing and cell-tropic determinant....

Protection against HIV-1 infection in hu-PBL-SCID mice by passive immunization with a neutralizing human monoclonal antibody against the gp120 CD4-binding site.(reprinted from AIDS, June 1995)(Periodical Report)(Abstract)
July 10, 1995... According to the authors' abstract of an article published in AIDS, "OBJECTIVE: Mice with severe combined immunodeficiency (SCID) transplanted with human peripheral blood lymphocytes (hu-PBL) have been shown to be useful as an animal model for...

Effectiveness of ultrasonic cleaning of dental instruments.(reprinted from American Journal of Dentistry, June 1995)(Periodical Report)(Abstract)
July 10, 1995... According to the authors' abstract of an article published in American Journal of Dentistry, "PURPOSE: To quantitate blood contamination present on dental instruments used for routine prophylaxis and to assess the effectiveness of ultrasonic...

Characterization of HIV type 1 from Romanian children: lack of correlation between V3 loop amino acid sequence and syncytium formation in MT-2 cells.(reprinted from AIDS Research and Human Retroviruses, May 1995)(Periodical Report)(Abstract)
July 10, 1995... According to the authors' abstract of an article published in AIDS Research and Human Retroviruses, "The biological properties and amino acid sequences of the third variable domain (V3 loop and flanking regions) of the env region of 34 HIV-1...

Seroreactivity of analogous antigenic epitopes in glycoprotein 120 expressed in HIV-1 subtypes A,B,C and D.(Reprinted from AIDS Research and Human Retroviruses, May 1995)(Periodical Report)(Abstract)
July 10, 1995... According to the authors' abstract of an article published in AIDS Research and Human Retroviruses, "This article describes the impact of sequence variation on the distribution and seroreactivity of linear antigenic epitopes in gp120 encoded in...

Molecular characterization of human immunodeficiency virus type 1 isolates from Venezuela.(reprinted from AIDS Research and Human Retroviruses, May 1995)(Periodical Report)(Abstract)
July 10, 1995... According to the authors' abstract of an article published in AIDS Research and Human Retroviruses, "Eight HIV-1 isolates from Venezuela have been characterized by nucleotide sequencing of the entire reverse transcriptase (RT)- and surface...

AMA calls for voluntary HIV screening of pregnant women.(American Medical Association)
July 3, 1995... Voluntary HIV testing should be available to all pregnant women, and the results should be available to physicians taking care of both mother and baby, the American Medical Association's policy-making arm decided at their 1995 annual...

NIAID launches three new AIDS vaccine trials.(National Institutes of Allergy and Infectious Diseases)
July 3, 1995... Three new trials of experimental vaccines to prevent HIV infection or AIDS recently began enrolling 144 total needed volunteers, the U.S. National Institutes of Allergy and Infectious Diseases (NIAID) announced. Volunteers are being...

New CD4-based drug could prevent infection after HIV exposure.(Progenics Pharmaceuticals Inc.'s CD4-IgG2)
July 3, 1995... A new fusion protein may be able to prevent people newly exposed to HIV from becoming infected with the virus. Such a drug could be used to prevent healthcare and laboratory workers from becoming infected after accidental exposures, and could...

New NNRTI in phase I clinical trials.(non-nucleotide reverse transcriptase inhibitor)(anti-HIV drug)
July 3, 1995... The first member of a new class of non-nucleotide reverse transcriptase inhibitors (NNRTIs) has entered Phase I clinical trials. The new drug, dubbed LY30046-HCL, is the first clinical candidate from the PETT series. It is as active against...

Thailand suffering from fear of AIDS patients; world conference this fall.(3rd International Conference on AIDS in Asia and the Pacific, Sept 17-22, 1995)
July 3, 1995... Thailand may be suffering from rising intolerance toward those who have HIV. Thailand is second only to India in Asia in terms of the number of carriers of HIV. The latest official statistics estimate that Thailand now has 700,000 people...

Anti-AIDS program in Paraguay targets prostitutes.
July 3, 1995... A twenty-year-old girl admits she's slept with 30 men this week. Her 18-year-old friend has been with 42 men. Once a month, the two prostitutes reveal their sexual secrets - not to a priest, but to Rosio Duria, a social worker employed by...

States' responses to demographic shifts in HIV/AIDS epidemic surveyed.
July 3, 1995... The AIDS Policy Center, Intergovernmental Health Policy Project (IHPP) at George Washington University, Washington, D.C., announced the publication of Changing Faces, Changing Directions: State Responses to the Demographic Shifts in the...

IL-10 contributes to AIDS-related B-cell lymphoma.(interleukin-10)
July 3, 1995... HIV induced interleukin-10 (IL-10) production plays a central role in the pathogenesis of AIDS lymphoma, a recent study concluded. Previous research has suggested that the pathogenesis of AIDS-related lymphoma is related to the induction of...

TB may exacerbate immune dysfunction in HIV+.(tuberculosis)
July 3, 1995... Stimulation of HIV-1 replication by Mycobacterium tuberculosis may exacerbate dysfunction of the host immune response in dually infected individuals, according to a report from New York University. It has been suggested that tuberculosis...

CDC says CD4 lymphocytopenia not new AIDS agent.(Centers for Disease Control and Prevention)
July 3, 1995... Unexplained CD4 T lymphocytopenia in children is unlikely to be a major public health problem, according to a report from the U.S. Centers for Disease Control and Prevention (CDC). Several recent reports have described profound CD4 lymphocyte...

Apache II system underestimates death risk of HIV+ in ICU.(Acute Physiology and Chronic Health Evaluation, intensive care unit)
July 3, 1995... The Acute Physiology and Chronic Health Evaluation II (APACHE II) prognostic scoring system significantly underestimates mortality risk in HIV-positive patients admitted to the medical intensive care unit with a CD4 cell count of 200 or less,...

HIV test should be given later in needlestick injuries.
July 3, 1995... French researchers say some people tested for HIV may be reassured too soon that they have not been infected. The doctors recommend revising guidelines for HIV testing so that people get a blood test eight months to a year after being pricked...

Oral ganciclovir has prophylactic activity.
July 3, 1995... A Phase I/II trial suggests that oral ganciclovir has pharmacokinetic, toxicity and antiviral profiles that may be beneficial for both maintenance therapy of cytomegalovirus (CMV) retinitis and prevention of CMV disease in HIV-infected persons....

Hyperthermia: possible treatment for HIV/AIDS?
July 3, 1995... Warming the body to temperatures well above normal shows promise as a treatment and possible cure for HIV/AIDS, according to a paper in the May/June 1995 issue of Alternative Medicine Journal. In the issue, Linda Shecterle, Peter Gasper,...

Treatment program for protease inhibitors announced.(Hoffmann-La Roche Inc. offers Invirase to HIV-infected people who are ineligible for clinical trials.)
July 3, 1995... Hoffmann-La Roche Inc., Nutley, New Jersey, announced the initiation of a limited international compassionate treatment program designed to supply Invirase (saquinavir) to patients who may benefit from the investigational treatment but are not...

RhG-CSF may reduce infection in neutropenic AIDS patients.(recombinant human granulocyte colony-stimulating factor)
July 3, 1995... Therapeutic use of recombinant human granulocyte colony-stimulating factor (rhG-CSF) at appropriate schedules in neutropenic AIDS patients could decrease the risk of infection or reduce the severity of occurring infections, according to a...

Phase I/II trial of soluble recombinant human interleukin-1 receptor (rhu IL-1R) in patients with human immunodeficiency virus-1 (HIV-1) infection.(Research Report)
July 3, 1995... According to an abstract submitted by the authors to the 31st Annual Meeting of the American Society of Clinical Oncology, held May 20-23, 1995, in Los Angeles, California, "Elevated serum levels of IL-1, a proinflammatory, proangiogenic...

A randomized trial of liposomal daunorubicin (DaunoXome) versus adriamycin, bleomycin and vincristine (ABV) in 232 patients with advanced AIDS-related Kaposi's sarcoma."(Research Report)
July 3, 1995... According to an abstract submitted by the authors to the 31st Annual Meeting of the American Society of Clinical Oncology, held May 20-23, 1995, in Los Angeles, California, "Kaposi's sarcoma (KS) is the most common tumor in patients with HIV-1...

Patient characteristics associated with clustering of RFLP patterns in isolates of Mycobacterium tuberculosis from an unselected population.(restriction fragment length polymorphisms)(Research Report)
July 3, 1995... According to an abstract submitted by the authors to the 95th General Meeting of the American Society for Microbiology, held May 21-25, 1995, in Washington, D.C., "Tuberculosis (TB) has resurfaced in the elderly, homeless, and HIV(+)...

HIV tat protein can regulate promoters of the insulin-like growth factor II gene in cultured leiomyosarcoma cells.(Research Report)
July 3, 1995... According to an abstract submitted by the authors to the 31st Annual Meeting of the American Society of Clinical Oncology, held May 20-23, 1995, in Los Angeles, California, "Among the complications of HIV infection in children is an unusually...

Oral immunization of mice with a live attenuated salmonella vector expressing recombinant gp 120 of HIV-1 on the surface of the vector, induces mucosal and systemic immunity against gp 120.(Research Report)
July 3, 1995... According to an abstract submitted by the authors to the 95th General Meeting of the American Society for Microbiology, held May 21-25, 1995, in Washington, D.C., "Protection against HIV-1 may require HIV specific immunity, consisting of...

In vitro assessment of the therapeutic potential of anti-HIV-1 monoclonal neutralizing antibodies.(Research Report)
July 3, 1995... According to an abstract submitted by the authors to the 95th General Meeting of the American Society for Microbiology, held May 21-25, 1995, in Washington, D.C., "The therapeutic potential of anti-HIV-1 neutralizing antibodies was assessed...

Only a very specific antisense 20mer oligodeoxyl-nucleotide inhibits HIV RNA dimer formation.(Research Report)
July 3, 1995... According to an abstract submitted by the authors to the 95th General Meeting of the American Society for Microbiology, held May 21-25, 1995, in Washington, D.C., "One of the unique features of HIV (also other retroviruses) is that viral RNA...

Procedure for detection of INH in body fluids using FPEC-GLC or CIGCMS.(isonicotinic acid hydrazide, frequency-pulsed electron-capture gas-liquid chromatography, chemical ionization gas chromatography mass spectrometry)(Research Report)
July 3, 1995... According to an abstract submitted by the author to the 95th General Meeting of the American Society for Microbiology, held May 21-25, 1995, in Washington, D.C., "A need exists for a sensitive selective procedure to quantitatively detect...

Protection against HIV-1 infection in hu-PBL-SCID mice by passive immunization with a neutralizing human monoclonal antibody against the gp 120 CD4-binding site. (reprinted from AIDS, June 1995)(human peripheral blood lymphocytes, severe combined immunodeficiency)(Periodical Report)(Abstract)
July 3, 1995... According to the authors' abstract of an article published in AIDS, "OBJECTIVE: Mice with severe combined immunodeficiency (SCID) transplanted with human peripheral blood lymphocytes (hu-PBL) have been shown to be useful as an animal model for...

An epitope-selective, transporter associated with antigen presentation (TAP)-1/2-independent pathway and a more general TAP-1/2-dependent antigen-processing pathway allow recognition of the HIV-1 envelope glycoprotein by CD8 CTL. (reprinted from the Journal of Immunology, June 1 1995)(Periodical Report)(Abstract)
July 3, 1995... According to the authors' abstract of an article published in Journal of Immunology, "The lysis of virally infected cells by CTLs requires the recognition of processed fragments of viral proteins presented in association with class I MHC...

Use of double gloves to protect the surgeon from blood contact during aesthetic procedures. (reprinted from Aesthetic Plastic Surgery, May-June 1995)(Periodical Report)(Abstract)
July 3, 1995... According to the authors' abstract of an article published in Aesthetic Plastic Surgery, "The potential for blood contact with nonintact skin puts operating room personnel at an increased risk of exposure to hepatitis or HIV virus. Frank...

Deferral of blood donors with risk factors for HIV infection saves lives and money in Zimbabwe. (reprinted from the Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, June 1, 1995)(Periodical Report)(Abstract)
July 3, 1995... According to the authors' abstract of an article published in Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, "We compared the cost-effectiveness of three strategies to avert transfusion-associated HIV infection in...

Role of radiotherapy in the treatment of epidemic Kaposi's sarcoma: experience with sixty-five cases. (reprinted from the Journal of the American Academy of Dermatology, June 1995)(Periodical Report)(Abstract)
July 3, 1995... According to the authors' abstract of an article published in Journal of the American Academy of Dermatology, "BACKGROUND: Treatment of Kaposi's sarcoma (KS) associated with HIV infection should improve often disfiguring lesions, with an...

HIV/AIDS-related behavior change among injecting drug users in different national settings. (reprinted from AIDS, June 1995)(Periodical Report)(Abstract)
July 3, 1995... According to the authors' abstract of an article published in AIDS, "OBJECTIVES: To identify factors associated with effective AIDS behavior change among injecting drug users (IDU) in different national settings. DESIGN: Cross-sectional...

An evaluation of four methods for the detection of Pneumocystis carinii in clinical specimens. (reprinted from Pathology, July 1995)(Periodical Report)(Abstract)
July 3, 1995... According to the authors' abstract of an article published in Pathology, "We undertook a prospective evaluation of 4 methods for the detection of Pneumocystis carinii in clinical specimens and compared an indirect immunofluorescence assay (IFA)...

Multicenter trial of octreotide in patients with refractory acquired immunodeficiency syndrome-associated diarrhea. (reprinted from Gastroenterology, June 1995)(Periodical Report)(Abstract)
July 3, 1995... According to the authors' abstract of an article published in Gastroenterology, "BACKGROUND/AIMS: Diarrhea is a significant problem in patients with acquired immunodeficiency syndrome (AIDS). The aim of this study was to determine octreotide...