AIDS Weekly articles from January 2003

AIDS Weekly archives from January 2003

Endosomal, lysosomal degradation suppression augments viral infectivity.
January 6, 2003... 2003 JAN 6 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Agents that inhibit cellular lysosomal or endosomal activity could increase susceptibility to HIV infection, researchers in the United States warn. Most...

Glutathione-loaded erythrocytes enhance antiretroviral treatment.
January 6, 2003... 2003 JAN 6 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in Italy have developed a novel method for improving the effiacy of antiretroviral therapy for HIV infection. "Monocyte-macrophages play a...

Hepatitis C virus presents risk for liver cancer in adults with AIDS.
January 6, 2003... 2003 JAN 6 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Government researchers have established a connection between hepatitis C virus (HCV) infection and liver cancer but not HCV infection and non-Hodgkin lymphoma...

Angiostatin prevents Tat-induced vasculopathy.
January 6, 2003... 2003 JAN 6 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - The antiangiogenic peptide angiostatin can prevent vascular damage triggered by HIV proteins, researchers in Italy report. "The HIV-Tat protein can be...

Leptin levels linked to antiretroviral-induced immune recovery.
January 6, 2003... 2003 JAN 6 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Leptin levels may be linked to immune recovery after antiretroviral therapy in pediatric HIV patients, researchers in Italy report. "Because leptin, the...

HIV makes hepatitis B significantly more lethal.
January 6, 2003... 2003 JAN 6 - (NewsRx.com & NewsRx.net) -- Men infected with a combination of hepatitis B virus and HIV are 17 times more likely to die from liver disease than men infected with hepatitis B alone, according to a study by researchers at Johns...

Bono, senator speak on fighting HIV virus in Africa.
January 6, 2003... 2003 JAN 6 - (NewsRx.com & NewsRx.net) -- Rock singer Bono joined U.S. Sen. Bill Frist on December 9, 2002, to plead for more U.S. money to fight AIDS in Africa. "The questions that were asked in Germany [about the Holocaust] a generation...

Boosted saquinavir or Kaletra results in HIV suppression at 24 weeks.
January 6, 2003... 2003 JAN 6 - (NewsRx.com & NewsRx.net) -- Data from the largest-ever study of boosted protease inhibitors demonstrated that a high proportion of HIV patients taking an investigational boosted saquinavir regimen (saquinavir 1000 mg with...

Chiron extends collaboration to explore delivery of HIV vaccine.
January 6, 2003... 2003 JAN 6 - (NewsRx.com & NewsRx.net) -- Genetronics, Inc., (GEB) has extended a collaborative agreement with Chiron Corp. (CHIR) to conduct additional experiments using electroporation, Genetronics' proprietary technology, to test an HIV DNA...

In vitro diagnostic test developer completes agreement with American distributor.
January 6, 2003... 2003 JAN 6 - (NewsRx.com & NewsRx.net) -- MedMira, Inc., (MIR) announced that it has reached a strategic investment agreement with its American distributor, American Health Diagnostics, LLC, (AHD). This agreement contemplates the issuance...

Targeted Genetics reacquires full rights to CF program.
January 6, 2003... 2003 JAN 6 - (NewsRx.com & NewsRx.net) -- Targeted Genetics Corp. (TGEN) announced that it has received notification from Celltech Group, plc, (CLL) of its decision to terminate a collaborative agreement between the companies in support of...

Report: South leads U.S. in HIV, AIDS but not in funding.
January 6, 2003... 2003 JAN 6 - (NewsRx.com & NewsRx.net) -- The South leads the country in new HIV infections and overall AIDS cases, yet lags in the amount of federal funding when compared with other regions, officials at a regional AIDS conference say. ...

Florida Medicaid initiates coverage for company's HIV drug resistance testing.
January 6, 2003... 2003 JAN 6 - (NewsRx.com & NewsRx.net) -- ViroLogic, Inc., (VLGC) announced that the Florida Medicaid Program has initiated a benefit coverage policy for phenotypic and genotypic HIV drug resistance testing as of November 15, 2002. This...

Cosalane additives improve intestinal absorption.
January 6, 2003... 2003 JAN 6 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in the United States have developed novel methods for improving the intestinal absorption of a promising anti-HIV agent. "Cosalane is a potent...

Protease inhibitor prodrugs show improved pharmacokinetics.
January 6, 2003... 2003 JAN 6 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in France have developed a novel method for improving the pharmacokinetics of HIV protease inhibitors. Pierre Vierling and colleagues at the...

Modified rabies virus vectors safe, effective.
January 6, 2003... 2003 JAN 6 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Novel rabies virus (RV)-based vaccines can safely protect animals against HIV infection, researchers in the United States report. RV-based vectors "show...

No more medical roulette: Publisher says internet will change in 2003.
January 6, 2003... 2003 JAN 6 - (NewsRx.com & NewsRx.net) -- NewsRx is celebrating its twentieth year as a publisher by adding 20 new weeklies. The company's CEO is predicting major changes in the publishing industry and Internet in 2003. The Atlanta-based...

New international coalition aims to expand global access to HIV/AIDS treatment.
January 6, 2003... 2003 JAN 6 - (NewsRx.com & NewsRx.net) -- A new international alliance - the International HIV Treatment Access Coalition (ITAC) - has been launched in Geneva and Dakar in an effort to boost efforts to provide access to antiretroviral drugs to...

Tecan enters agreement on automated sample preparation systems.
January 6, 2003... 2003 JAN 6 - (NewsRx.com & NewsRx.net) -- Abbott Laboratories (ABT) and Tecan announced a long-term supply agreement for the development and commercialization of an automated sample preparation system for molecular diagnostic assays. The...

Nelson Mandela champions AIDS fight in South Africa.
January 6, 2003... 2003 JAN 6 - (NewsRx.com & NewsRx.net) -- Wearing a T-shirt with the words "HIV-positive" emblazoned across the front, Nelson Mandela declared war on AIDS December 12, 2002, and urged people to practice safe sex or abstain completely. The...

Functional MRI can find brain abnormalities in asymptomatic patients.
January 13, 2003... 2003 JAN 13 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Functional magnetic resonance imaging (fMRI) can provide early warning of neurologic morbidity in HIV patients, researchers in the United States report. ...

Actinomycin D stimulates HIV replication.
January 13, 2003... 2003 JAN 13 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - The anticancer drug actinomycin D (ActD) should not be used to treat HIV patients, researchers in the United States warn. "ActD has been reported to be a...

Morphine enhances macrophage infection through chemokine, coreceptor modulation.
January 13, 2003... 2003 JAN 13 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in the United States have elucidated the mechanisms by which opiates increase macrophage susceptibility to HIV. "Injection drug use remains a...

Interleukin-2 improves CD4 cell recovery.
January 13, 2003... 2003 JAN 13 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - A T cell-stimulating cytokine could be valuable for treating HIV patients with poor CD4 cell recovery despite otherwise successful antiretroviral therapy,...

Tumor necrosis factor gene mutations may promote lipodystrophy.
January 13, 2003... 2003 JAN 13 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in the United Kingdom have identified a genetic risk factor for HIV wasting syndrome. The inflammatory cytokine tumor necrosis factor...

U.N. official: West's response to African AIDS crisis woefully inadequate.
January 13, 2003... 2003 JAN 13 - (NewsRx.com & NewsRx.net) -- The Western world's response to the unfolding humanitarian crisis in Africa caused by AIDS and hunger is woefully inadequate, a top U.N. official says. While people in developed countries who...

Pfizer, Pfizer Foundation announce new and expanded HIV/AIDS initiatives.
January 13, 2003... 2003 JAN 13 - (NewsRx.com & NewsRx.net) -- Pfizer, Inc., and The Pfizer Foundation announced new and expanded initiatives designed to address the growing threat to human health posed by the HIV/AIDS pandemic. On the second anniversary of...

New book explores how communication can combat HIV/AIDS.
January 13, 2003... 2003 JAN 13 - (NewsRx.com & NewsRx.net) -- About 95% of the 40 million people with HIV/AIDS live in developing countries in Latin America, Africa and Asia - the epicenter of the AIDS epidemic. As governments and health officials look for...

World Bank gives $12.6 million to Sri Lanka.
January 13, 2003... 2003 JAN 13 - (NewsRx.com & NewsRx.net) -- The World Bank will provide U.S. $12.6 million to Sri Lanka to fight the spread of the HIV virus and reduce the stigma attached with the disease, a bank statement says. The island nation of 18.6...

Sex workers in Mexico-U.S. border regions potential source for HIV/AIDS spread.
January 13, 2003... 2003 JAN 13 - (NewsRx.com & NewsRx.net) -- The social behavior of sex workers and transportation workers along the U.S.-Mexico border has the potential to spread HIV and AIDS through North and Central America in much the same way the disease...

Biopharmaceutical company, IAVI, sign vaccine manufacturing agreement.
January 13, 2003... 2003 JAN 13 - (NewsRx.com & NewsRx.net) -- Transgene (TRGNY) announced that it has entered into a collaborative agreement with the International AIDS Vaccine Initiative (IAVI) to manufacture preclinical lots of IAVI's constructs for a novel...

VaxGen soars on fast-track status for HIV/AIDS vaccines.
January 13, 2003... 2003 JAN 13 - (NewsRx.com & NewsRx.net) -- Shares of drug maker VaxGen rose December 16, 2002, after the U.S. Food and Drug Administration designated its HIV/AIDS vaccine candidates as fast-track products for the prevention of the disease. ...

ELISpot and ELISA assays detect macaque cytokines.
January 13, 2003... 2003 JAN 13 - (NewsRx.com & NewsRx.net) -- According to a study from Sweden, "Evaluation of cytokine production in macaques has been hampered by a lack of availability of optimized and standardized immunoassays such as ELISA [enzyme-linked...

Immigrants often more at risk for HIV once they enter the United States.
January 13, 2003... 2003 JAN 13 - (NewsRx.com & NewsRx.net) -- In a study of 61,000 Californians who sought treatment for sexually transmitted diseases, researchers found that those foreign-born immigrants who were infected with HIV most likely contracted the...

Methamphetamine use strongly exacerbates virus-induced neuronal damage.
January 13, 2003... 2003 JAN 13 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Methamphetamine use by HIV patients may dramatically increase their risk of neurologic complications, researchers in the United States warn. "The human...

CADA inhibits HIV, human herpesvirus 7 activity.(CADA: cyclotriazadisulfonamide)
January 13, 2003... 2003 JAN 13 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers have identified a novel agent that inhibits the activity of HIV and other viral pathogens. Kurt Vermeire and colleagues at Katholieke...

Agreement on access to cheap medicines remains elusive.
January 13, 2003... 2003 JAN 13 - (NewsRx.com & NewsRx.net) -- A key meeting of the World Trade Organization was suspended December 12, 2002, because of continuing differences between the United States and other rich countries wanting to protect their...

Biotech firm to slash AIDS drug price in Africa.
January 13, 2003... 2003 JAN 13 - (NewsRx.com & NewsRx.net) -- Gilead Sciences has announced will dramatically lower the price it charges for its AIDS drug in all of Africa and another 15 "least-developed" countries. The biotechnology firm, based in Foster...

Report: Novel compounds to drive the neuropathic pain market.
January 13, 2003... 2003 JAN 13 - (NewsRx.com & NewsRx.net) -- The current U.S. neuropathic pain market is worth an estimated $430 million, according to "Neuropathic Pain," a new report from EP Publications. U.S. Food and Drug Administration-approved products...

CPI-1189 safe but ineffective.(Brief Article)
January 20, 2003... 2003 JAN 20 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in the United States report disappointing results for an agent with potential for treating HIV-related central nervous system (CNS) morbidity. ...

Viral Tat protein enhances monocyte adhesion through nuclear factor-kappaB activation.(Brief Article)
January 20, 2003... 2003 JAN 20 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in the United States have shed new light on the effects of the HIV Tat protein on endothelial cells. Viral Tat "released from HIV-1-infected...

Mimicked gene defect affords HIV protection.(Brief Article)
January 20, 2003... 2003 JAN 20 - (NewsRx.com & NewsRx.net) -- UCLA and California Institute of Technology researchers have developed a new gene therapy approach that prevents the AIDS virus from entering human cells. The technique offers a potential way to treat...

Infection affects dendritic cell counts and phenotype.(Brief Article)
January 20, 2003... 2003 JAN 20 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in the United States have elucidated the effects of HIV infection on antigen-presenting cells. "Dendritic cells (DCs) are postulated to be...

High-dose interferon effective in patients coinfected with hepatitis C.(Brief Article)
January 20, 2003... 2003 JAN 20 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Interferon (IFN) treatment may be effective for both HIV and hepatitis C virus (HCV) infection, according to a researcher in Japan. Working at Ogikubo...

New AIDS vaccine said promising.(Brief Article)
January 20, 2003... 2003 JAN 20 - (NewsRx.com & NewsRx.net) -- An experimental vaccine against the monkey form of AIDS sharply reduced but did not eliminate the amount of the virus in the animals' blood. Evidence of the virus in the blood cells of macaques...

Report: China plans to mass-produce four AIDS drugs.(Brief Article)
January 20, 2003... 2003 JAN 20 - (NewsRx.com & NewsRx.net) -- China has announced plans to start mass-producing low-cost AIDS drugs in January 2003, the official Xinhua News Agency says. Xinhua did not say which drugs will be made, but said the price would...

Cell-based vaccine counteracts virus in monkeys.(Brief Article)
January 20, 2003... 2003 JAN 20 - (NewsRx.com & NewsRx.net) -- AIDS virus researchers have long sought a vaccine that could work as a treatment for HIV-infected patients. Now they may have edged closer to that goal in experiments on macaques. Macaques develop...

Pape receives France's Legion of Honor for 2 decades of service in Haiti.(Brief Article)
January 20, 2003... 2003 JAN 20 - (NewsRx.com & NewsRx.net) -- Dr. Jean W. Pape, an internationally recognized infectious disease expert and Professor of Medicine at Weill Cornell Medical College, has received France's highest distinction, the Legion d'Honneur,...

Easier drug schedules help cognitively impaired HIV patients.(Brief Article)
January 20, 2003... 2003 JAN 20 - (NewsRx.com & NewsRx.net) -- In a study that used computerized pill bottles to track medication adherence, HIV-infected patients with cognitive problems were far more likely to miss doses when they had to take pills 3 times a day,...

NDA submitted for investigational protease inhibitor atazanavir.(Brief Article)
January 20, 2003... 2003 JAN 20 - (NewsRx.com & NewsRx.net) -- Bristol-Myers Squibb Company (BMY) announced the submission of a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for atazanavir, an investigational protease inhibitor under...

Specialist regulation approved by state of California.(Brief Article)
January 20, 2003... 2003 JAN 20 - (NewsRx.com & NewsRx.net) -- Groundbreaking legislation ordering California HMOs to provide standing referrals to AIDS specialists for patients infected with HIV will finally take effect in mid-January 2003. The bill, AB...

Interleukin-18 augments HIV replication.(Brief Article)
January 20, 2003... 2003 JAN 20 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Interleukin (IL)-18 enhances HIV replication, researchers in Italy report. IL-18 "is a recently identified immunoregulatory cytokine expressed by...

Lymphocyte toxicity test effective for finding sulfonamide toxicity.(Brief Article)
January 20, 2003... 2003 JAN 20 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in Canada have identified an effective method for detecting sulfonamide toxicity in HIV patients. Patients infected with HIV "are at higher...

Nucleoside reverse transcriptase inhibitors induce superoxide-mediated cardiomyopathy.(Brief Article)
January 20, 2003... 2003 JAN 20 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in the United States have elucidated the effects of nucleoside reverse transcriptase inhibitors (NRTIs) on heart tissue. NRTIs "have been used...

Mitox tests for mitochondrial toxicity discussed at HIV-1 DART conference.(Brief Article)
January 20, 2003... 2003 JAN 20 - (NewsRx.com & NewsRx.net) -- Primagen presented new preclinical data on its proprietary Mitox tests at the HIV-1 DART conference in Florida. Primagen's Mitox tests measure both mitochondrial DNA and RNA in relation to...

State Department seeks boost to advance wars on terrorism, AIDS.(Brief Article)
January 20, 2003... 2003 JAN 20 - (NewsRx.com & NewsRx.net) -- The U.S. State Department is seeking sizable budget increases to fight the global AIDS epidemic and to counter terrorism, including more than $1 billion to fortify embassies and tighten security,...

Liver fat buildup linked to insulin resistance.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in Finland have shed new light on the factors responsible for HIV-associated lipodystrophy. "Lipodystrophy in several animal models is...

CD4 cell phenotypes linked to nonprogression.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - Researchers in the United Kingdom have identified CD4 cell phenotypes linked to HIV nonprogression. "HIV immunity is likely CD4 T cell dependent,"...

Need for social support deters HIV patients from taking their drug 'cocktails'.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- Social support may play a small but potentially important role in helping HIV-positive people adhere to the complicated schedules for taking their drug "cocktails" to control the virus that causes...

HIV Vpr suppresses human monocyte IL-12 production by enhancing glucocorticoid action.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to researchers from the United States, "The HIV-1 protein Vpr has glucocorticoid receptor coactivator activity, potently increasing the sensitivity of glucocorticoid target tissues to...

HIV-1 evades antibody-mediated neutralization by masking receptor-binding sites.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to a study from the United States, "The ability of human immunodeficiency virus (HIV-1) to persist and cause AIDS is dependent on its avoidance of antibody-mediated neutralization. The virus...

Rapid apoptosis induction in HIV-specific murine CTLs by short exposure to antigenic peptide.(cytotoxic lymphocytes)
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- "During primary viral infection, in vivo exposure to high doses of virus causes a loss of Ag-specific CD8+ T cells. This phenomenon, termed clonal exhaustion, and other mechanisms by which CTLs are...

California sees spike in number of reported AIDS cases.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- California's new HIV reporting system has been hurt in its first 6 months by the failure of some doctors and clinics to provide information required by law, health officials said. If the problems...

Vancouver Indian injection drug users twice as likely as non-Indians to become HIV infected.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- Indians who inject drugs in Vancouver's Downtown Eastside are becoming infected with HIV at almost twice the rate of their non-Indian counterparts, the coauthor of a new study said. The study...

Grant funds research to develop microbicide barrier.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- The U.S. National Institutes of Health (NIH) has awarded a grant of nearly $8 million to the University of Pittsburgh and Magee-Womens Research Institute (MWRI) to fund research aimed at developing a...

Increased peripheral neuropathy risk seen in patients coinfected with HIV-1 and HTLV-2.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to a study from Italy, "One thousand one hundred fifty-two HIV-1-positive patients were screened for HTLV-2 infection, and the AIDS-free coinfected individuals were consecutively included in...

Bartonella henselae often spread by feline pets.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- "Bartonella henselae causes severe disease in immunocompromised individuals," according to researchers in the United States. "B. henselae was isolated from 12 human immunodeficiency virus...

M. avium modulates macrophage expression of signaling and adhesion molecules.(Mycobacterium)
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to a study from the United States, "Mycobacterium avium is a facultative intracellular pathogen cleared rapidly via intact host defense mechanisms. In the absence of adequate T-cell...

Docking of HIV Vpr to nuclear envelope mediated by interaction with the nucleoporin hCG1.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to recent research from France, "The HIV-1 genome contains several genes coding for auxiliary proteins, including the small Vpr protein. Vpr affects the integrity of the nuclear envelope and...

Role of HIV-specific cytotoxic T cells in long-term nonprogression questioned.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to a study from England, "The mechanisms underlying non-progression in HIV-1 infection are not well understood; however, this state has been associated previously with strong HIV-1-specific...

Selectively reduced tat mRNA heralds decline in productive macrophage infection.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to a study from Australia, "The transcription and splicing of human immunodeficiency virus type 1 (HIV-1) mRNA in primary blood monocyte-derived macrophages (MDM) and CD4+ peripheral blood...

Urine antibody testing effective in endemic areas.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- Researchers in the United States conducted a study "to evaluate the effectiveness of urine screening to detect HIV-infected individuals in high-prevalence communities." "Urine HIV testing was...

Antiviral peptides derived from RANTES amino acid sequences.(regulated upon activation, normal T-cell expressed and secreted)(Brief Article)
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to a study from the United States, "Fifteen acetyl-peptide-amides with partial amino acid sequences of RANTES (regulated upon activation, normal T-cell expressed and secreted), all Cys...

Gemfibrozil provides limited benefit for patients with protease inhibitor-associated hypertriglyceridemia.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to recent research from Australia, "hypertriglyceridemia is common in patients with HIV, especially those taking protease inhibitors or with lipodystrophy, [and is] frequently observed at...

Highly active antiretroviral therapy lowers Kaposi sarcoma-associated herpesvirus levels.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- Researchers in England conducted a study "to investigate the effect of highly active antiretroviral therapy (HAART) on circulating Kaposi sarcoma (KS)-associated herpesvirus (KSHV) load in HIV-infected...

Intrathecal immunoactivation persists despite effective antiretroviral therapy.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- Researchers in Sweden conducted a study "to study the effect of antiretroviral combination treatment on intrathecal immunoactivation in HIV-1 infection." "Lumbar punctures were performed at...

New data suggest a prolongation of time off HAART without significant viral rebound.(hghly ative atiretroviral terapy)
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- Hemispherx Biopharma, Inc., (HEB) presented new data from a phase IIB clinical trial of its experimental compound, RNA-based Ampligen, on Structured Treatment Interruption (STI) in HIV. Gary...

Plasma HIV RNA levels linked to herpes simplex virus activity.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to a study from the United States, "In early trials of antiretroviral therapy, acyclovir was associated with increased survival by an unknown mechanism. The hypothesis that subclinical...

Rapid reconstitution of humoral immunity against CMV but not HIV seen after HAART.(cytomegalovirus, highly active antiretroviral therapy)
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- Researchers in England conducted a study "to determine the kinetics of reduction in human cytomegalovirus (HCMV) load and specific anti-glycoprotein B (gB) immune responses in patients with concurrent...

Tenofovir provides superior protection for dendritic, Langerhans cells.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to recent research from Belgium, "Langerhans cells and interstitial dendritic cells are the earliest targets for HIV infection through sexual transmission of HIV. Metabolism of nucleoside...

Behavior change determines impact of treatment on HIV transmission in advanced epidemics.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- In a recent study, researchers in Switzerland conducted a study "to assess how the impact of sexually transmitted disease (STD) treatment on HIV incidence varies between stages of the HIV epidemic."...

T-cell responses induced in humans immunized with a env/rev-containing DNA vaccine.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- According to recent research from the United States, "an effective HIV-1 vaccine will likely need to induce strong cell-mediated immunity in humans. Therefore, we examined the ability of a DNA HIV-1...

New AIDS treatment program to offer lifelong care for families in Thailand.
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- A new health program will provide lifelong care for Thailand's babies, mothers and fathers who are HIV-positive, the Thai Red Cross says. The program will help an estimated 500 pregnant women,...

Advances in new drug discovery program profiled.(Achillion Pharmaceuticals)(Brief Article)
January 27, 2003... 2003 JAN 27 - (NewsRx.com & NewsRx.net) -- At the JP Morgan H&Q Healthcare Conference held January 6-9, William G. Rice, PhD, CEO of Achillion Pharmaceuticals, reported on the clinical and preclinical progress of Achillion's infectious disease...