AIDS Weekly articles from February 2004

AIDS Weekly archives from February 2004

Aminoglycoside-arginine conjugates show promise as antiretroviral agents.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- A series of novel compounds show great promise as antiretroviral agents. In a recent study, scientists in Israel "designed and synthesized aminoglycoside-arginine conjugates (AACs) as potential...

Opioids can impair neuroprotective effects of retinoids.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Opioid use and abuse can counteract the neuroprotective effects of retinoids in HIV patients. "Among injection drug users, human immunodeficiency virus (HIV) type 1 infection may be associated with...

CsA derivatives show promise as antiretroviral agents.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- A series of novel CsA-derived agents strongly inhibit HIV activity with limited immunomodulatory effects. In a study conducted by M. Evers and colleagues at Aventis Pharma S.A. in Vitry-sur-Seine,...

L-chicoric acid analogues strongly inhibit HIV integrase.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- A series of novel L-chicoric acid derivatives provide improved inhibition of HIV integrase compared with their parent drugs. "HIV integrase catalyzes the integration of HIV DNA copy into the host...

Rhesus monkey Rhadinovirus valuable as KSHV model.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Rhesus monkey Rhadinovirus (RRV) can facilitate the study of the virus responsible for Kaposi sarcoma. According to published research from the United States, RRV "is one of the closest...

Human leukocyte elastase can act as HIV coreceptor.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Human leukocyte elastase (HLE) can act as an HIV coreceptor. According to recent research from New York, HLE "interacts with HIV-1 glycoprotein (gp)41, suggesting a nonenzymatic receptor function...

Clinton: Costs of AIDS tests will plummet in Africa, Caribbean.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- An agreement with five medical technology companies could help reduce the costs of treating HIV-infected people in Africa and the Caribbean by up to 80%, former President Bill Clinton said in announcing...

Indian gay groups to fight AIDS among homosexuals, street children.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- India's secretive gay community is emerging to fight the fast spread of the AIDS disease among homosexuals and street children. At least 10 homosexual groups have formed a common platform called...

Partnership extended with vaccine research groups.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Targeted Genetics Corporation (TGEN) announced a 3-year extension of its collaboration agreement with the International AIDS Vaccine Initiative (IAVI) and Columbus Children's Research Institute (CCRI)...

To avoid detection, HIV disrupts immune cell migration.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- The HIV protein Nef sparked intensive research after observations that patients with a rare strain of HIV lacking Nef took a very long time to develop AIDS symptoms. Nef has been linked to molecules...

Fullerene C[subscript]60 derivatives have antiretroviral activity.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Novel [60]fullerene derivatives have demonstrated potent antiretroviral activity. According to recent research from Italy, "A new series of bis-functionalized fullerene C[subscript]60 derivatives...

Lysine sulfonamides inhibit HIV protease.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Novel sulfonamides show promise as HIV protease inhibitors. In a recent study from Canada, "A series of Nalpha-isobutyl-Nalpha-arylsulfonamido-(Nepsilon acyl) lysine and lysinol derivatives were...

Novel nucleoside analogues fail to show anti-HIV activity.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- A series of novel nucleoside analogues have failed to demonstrate anti-HIV activity. D. Egron and colleagues working at the University of Montpellier II described the results of their "detailed...

Leading AIDS experts criticize U.S.-sponsored HIV vaccine trial in Thailand.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Several national AIDS experts criticized a U.S. government-sponsored clinical research trial of an AIDS vaccine in Thailand in a recent journal report. The 22 researchers said that there are no...

UNAIDS responds to Kenyan charges of HIV prevalence overestimation.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Recent news reports claiming that UNAIDS and World Health Organization (WHO) HIV/AIDS estimates are "overestimated" are unfounded, according to the United Nations group. The reports cited a...

Moderate exercise improves HQOL in HIV patients.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- A moderate exercise regimen can significantly improve the physical well-being of HIV patients. Scientists in Germany conducted a study "to examine the effects of a 16-week exercise intervention on...

Reversible cardiomyopathy reported after perinatal HIV infection.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- The first known case of reversible cardiomyopathy after perinatal HIV infection has been reported. Cardiologists in Brazil described their experience treating "a patient with advanced perinatal...

Smallpox likely historic cause of CCR5-Delta32 mutation.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Contrary to conventional wisdom, smallpox is the likely historic cause of the CCR5-Delta32 mutation in Europeans. "The high frequency, recent origin, and geographic distribution of the CCR5-Delta32...

When it comes to contact notification, HIV is not TB.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- When it comes to contact notification, HIV infection must be treated differently than tuberculosis. According to published research from the United States, "HIV partner notification can help...

Dried blood suitable for HIV diagnosis in the field.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Dried blood samples are suitable for diagnosis of HIV under field conditions. According to published research from Zambia, "The increasing availability of antiretroviral drugs to HIV-infected...

Chromosomal events in HIV transcriptional activation clarified.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- The process of HIV transcriptional activation has been elucidated. "In HIV-1 infected cells, the LTR promoter, once organized into chromatin, is transcriptionally inactive in the absence of...

PTSD has some beneficial effects in HIV patients.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Surprisingly, PTSD appears to have some beneficial effects in HIV patients. "Previous research has reported rates of posttraumatic stress disorder (PTSD) following diagnosis with a life-threatening...

First case of ITG in HIV patient without hepatitis reported.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- A unique case of ITG in an HIV patient without hepatitis has been reported. Nephrologists in Pennsylvania described "the first case of immunotactoid glomerulopathy (ITG) in a human immunodeficiency...

M. tuberculosis co-infection possible in HIV CAP patients.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- M. tuberculosis co-infection should be tested for in HIV patients with refractory CAP. According to physicians in South Africa, "Pulmonary infections with more than one organism are common in human...

Novel regimen may improve disseminated aspergillosis survival.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- A novel treatment regimen may improve survival in disseminated aspergillosis patients. Researchers in Israel conducted a study "to assess the efficacy of amphotericin B (AMB), AMB-intralipid...

Delayed rectal viral dissemination seen in acutely SIV-infected macaques.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Surprisingly, viral activity is subdued shortly after rectal SIV infection in macaques. "Rectal infection of macaques by SIV is a model for rectal HIV transmission," according to virologists in...

HIV Vpu overcomes dominant host restriction in human cells.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- The HIV Vpu protein overcomes a dominant host restriction mechanism in human cells. "Human cells resist viral infections by a variety of mechanisms. Viruses must overcome host cell restrictions to...

HIV nuclear entry does not require mitosis in cycling cells.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- HIV nuclear entry is mitosis-independent in cycling cells. "An essential step in human immunodeficiency virus type 1 (HIV-1) replication is the movement of the viral preintegration complex from the...

Mechanisms of NK cell impairment during HIV infection identified.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- The molecular mechanisms of natural killer (NK) cell impairment during HIV infection have been identified. NK cells "play a central role in host defense against various pathogens," scientists in...

"Sengas" can effectively teach HIV prevention behavior to Ugandan girls.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- The cooperation of traditional "sengas" can improve anti-HIV interventions for Ugandan girls. "Although adolescent girls in Uganda are particularly vulnerable to HIV infection, providing relevant...

Efficacy of HIV VCT in Thailand evaluated.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- The efficacy of HIV VCT programs in Thailand has been evaluated. "The Thai government began HIV voluntary counselling and testing (VCT) in all provinces in 1992," researchers there explained. ...

Atazanavir is novel azapeptide inhibitor of HIV-1 protease.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Atazanavir is a novel azapeptide inhibitor of the HIV-1 protease. "Atazanavir is a novel azapeptide protease inhibitor (PI) that has been approved by Food and Drug Administration (FDA) for use in...

Viral fitness determines viral rebound during treatment interruptions.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- HIV fitness determines viral rebound during planned therapy interruptions. According to recent research from Switzerland, "Human immunodeficiency virus type 1 (HIV-1) isolates from 20 chronically...

Argentina IDUs have high HIV rate.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Drug injecters in Argentina have a high rate of HIV infection. Researchers there conducted a study "to compile published data and to describe the prevalences of human immunodeficiency virus (HIV)...

FDA approves Invirase Boosted with ritonavir for use in treatment of HIV/AIDS.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Roche announced U.S. Food and Drug Administration (FDA) approval of its protease inhibitor Invirase (saquinavir mesylate 1000 mg) for use with ritonavir (100 mg) in combination regimens for the...

Lymph node TB characterized in HIV+ and HIV- patients.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- The features of lymph node tuberculosis have been characterized in HIV and other patients. "Lymph node tuberculosis is the most frequent form of extrapulmonary tuberculosis especially in...

Specialist clinic service for HIV+ mineworkers helps prevent TB.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- A novel clinic helps prevent tuberculosis and other infections in HIV+ mineworkers. "Occupational settings offer an ideal opportunity to provide preventive health services for HIV-infected workers,"...

IgG antibodies confer sterilizing protection to SHIV-infected macaques.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Transfer of neutralizing IgG antibodies to macaques 6 hours (but not 24 hours) after SHIV infection conferred sterilizing protection. According to a study from the United States, "Passive transfer...

Vaccinia virus DIs expressing SIV gag controls SHIV in monkeys.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Intravenous inoculation of replication-deficient recombinant vaccinia virus DIs expressing simian immunodeficiency virus (SIV) gag controls highly pathogenic SHIV in monkeys. "To be effective, a...

HIV genital tract shedding linked to plasma viremia.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- HIV genital tract shedding is correlated with plasma viremia. In a recent study, researchers "examined 30 HIV-infected women in Manila to assess the relationship between cervicovaginal and plasma...

FDA approves Pegasys prefilled syringes.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Roche announced that the U.S. Food and Drug Administration (FDA) has approved prefilled syringes of Pegasys (Peginterferon alfa-2a) for the treatment of chronic hepatitis C. Pegasys, a pegylated...

LightCycler, TaqMan tests equally suitable for pediatric MRD measurement.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- LightCycler- and TaqMan-based tests are equally suitable for measuring MRD in pediatric ALL patients. "Quantification of residual leukemic cells at early time points during therapy can reliably...

Safety blood collection needle product line launches in U.S.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Specialized Health Products International, Inc., (SHPI) and Kendall, a business unit of Tyco Healthcare, announced the U.S. market launch of a proprietary line of safety blood collection products, based...

U.S. patent granted for treatment of human papillomavirus infections.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Advanced Viral Research Corp. (ADVR) announced that it has been awarded U.S. Patent Number 6.670,118 entitled "Method for Treating Papillomavirus Infections." The patent describes the use of AVR118...

Latex agglutination TB test effective.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- A novel assay shows promise for mass tuberculosis testing. Researchers in India described the "large-scale validation of a simple latex agglutination test for the diagnosis of tuberculosis". ...

Factors affecting GB virus viability identified.
February 2, 2004... 2004 FEB 2 - (NewsRx.com & NewsRx.net) -- A number of factors affecting GBV-C viability have been identified. "GB virus C/hepatitis G virus (GBV-C) replication in vitro is inefficient and inconsistent," virologists in the United States...

Liminoids strongly inhibit HIV protease activity.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- A pair of novel liminoids act as potent HIV protease inhibitors. "In the last years several plant-derived natural compounds have been screened for their anti-HIV activity in order to find lead...

STAT1 blockade shows promise for clearance of latent HIV reservoirs.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- STAT1 blockade shows promise for the clearance of HIV reservoirs in patients with latent infection. "Current highly active antiretroviral therapy (HAART) cannot eliminate HIV-1 from infected...

Lavendamycin analogues show promise as antiretroviral agents.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- A series of lavendamycin analogues show promise as antiretroviral agents. In a recent study from Indiana, "Novel lavendamycins including two water soluble derivatives were synthesized via short and...

Liver transplantation feasible in HIV/HCV-coinfected patients.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Liver transplantation can be feasible for patients infected with both HIV and hepatitis C virus (HCV). "The prognosis of HIV infection has been modified by antiretroviral therapy," scientists in...

Yeast system facilitates study of HIV integrase.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- A novel yeast system facilitates the study of they HIV IN enzyme. "Human immunodeficiency virus type I (HIV-1) integrase (IN) catalyzes the insertion of the viral genome into the host cell DNA, an...

Serum SDF-1 inactivated during HIV infection.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Serum SDF-1 is inactivated during HIV pathogenesis. "The chemokine stromal-derived factor-1 (SDF-1) can block human immunodeficiency virus type I (HIV-1) infection in vitro by binding to the CXC...

Media organizations unite to fight HIV/AIDS.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Leaders of more than 20 media companies from around the world agreed to join a multimillion dollar campaign January 14, 2004 to educate people about AIDS via the airwaves. "This is one of the...

Bulgarian medics trial postponed.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- A court in Tripoli, Libya, on January 12, 2004, postponed the trial of six Bulgarian medics accused of intentionally infecting more than 400 children with the AIDS virus, court officials said. The...

Thailand rejects criticism of AIDS vaccine trial.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Thailand dismissed criticism by American HIV researchers that a massive test of a possible AIDS vaccine on thousands of healthy Thais would fail, saying the U.S.-funded trial still has hopes of breaking...

IND application filed for protease inhibitor GS 9005.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Gilead Sciences, Inc., (GILD) has submitted an investigational new drug (IND) application to the U.S. Food and Drug Administration to evaluate GS 9005 (formerly known as GS 4338) as a potential new...

AIDS activists fight for more affordable drugs.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Thailand activists on January 17, 2004 urged AIDS sufferers and their supporters worldwide to use a legal victory against a U.S. pharmaceuticals giant in their fight for cheaper and more available drugs...

Gene product restricts HIV-1 replication in resting CD4+ lymphocytes.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- The gene product Murr1 restricts HIV-1 replication in resting CD4+ lymphocytes. "Although human immunodeficiency virus-1 (HIV-1) infects quiescent and proliferating CD4+ lymphocytes, the virus...

RNAi program initiated to develop therapies for diseases associated with CMV.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Further expanding its collaboration with a developer of RNA interference (RNAi) technology, CytRx Corporation (CYTR) announced that it has signed a new agreement with the University of Massachusetts...

Agreement to admit HIV-positive children into Nairobi's public schools approved.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- A judge in Nairobi, Kenya, approved an agreement January 9th, 2004, between the Ministry of Education and the country's oldest and largest AIDS orphanage under which public primary schools will admit...

HIV vector T-cell transduction efficiency is not pseudotype-dependent.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- The T-cell transduction efficiency of HIV vectors - unlike murine leukemia virus (MLV) vectors - is not pseudotype-dependent. "The success of several gene therapeutic approaches requires efficient...

To tackle poverty: Empower women and educate girls, U.N. leader says.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- The greatest weapon in the war against poverty is the empowerment of women and the education of girls, United Nations Secretary-General Kofi Annan said January 15, 2004, calling for international...

Prototype of a portable detector for protein diagnosis developed.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- "POCKET" is the prototype of a novel portable and battery-driven protein detector that has been developed at Harvard University in Cambridge, Massachusetts. This simple and inexpensive, yet reliable...

Jury finds Iowa City man guilty of criminal transmission of HIV.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- A Benton County, Iowa, jury deliberated for two hours before finding an Iowa City man guilty of criminal transmission of HIV. The verdict came January 13, 2004. Adam Musser, 23, testified in his...

New drug class may enable body's immune system to halt HIV infection.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Trillium Group and the University of Rochester Medical Center (URMC) announced that the University Technology Seed Fund will invest in the formation of OyaGen, Inc., a start-up company at work on a new...

HIV identification bill moves through committee.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Krista Wood had always been opposed to recording the names of AIDS patients in the clinic she runs in Paducah, Kentucky. Financial realities changed her mind. Kentucky identifies HIV-infected...

India's Catholic Church issues guidelines for treating HIV/AIDS.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- A priest's refusal to bury a parishioner who died of AIDS in the church cemetery has compelled the Roman Catholic Church in the southern Indian state of Kerala to ask its members to show compassion...

Low B-cell counts linked to heightened Kaposi sarcoma risk.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Low B-cell counts have been linked to a heightened risk of KS in HIV/AIDS patients. According to recent research from England, "Infection with HIV-1 is known to impair B-cell function." "To...

Serum preferable to plasma for KSHV load testing.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Serum is preferable to plasma for KSHV load testing in KS patients. "Human herpesvirus 8 (HHV-8) (or Kaposi sarcoma [KS]-associated herpesvirus) is associated with all forms of KS," and "HHV-8 DNA...

PMG augments glutamate output from infected macrophages.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Mitochondrial glutaminase augments glutamate production from HIV-infected macrophages. "Dysfunction in mononuclear phagocyte (MP, macrophages and microglia) immunity is thought to play a significant...

Role of CD40L dysregulation in HIV-related APC impairment reviewed.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- The role of CD40L dysregulation in HIV-induced impairment of APC function has been reviewed. "Cellular interactions between antigen-presenting cells and activated CD4+ T cells are central to the...

C. albicans cell wall adhesin identified.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- A Candida albicans gene involved in epithelial cell adhesion has been identified. According to a study from the United States, C. albicans "adhesion to host tissues contributes to its virulence and...

Molecular assay enables noninvasive PCP monitoring.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- A novel molecular assay enables noninvasive monitoring of PCP progression in AIDS patients. In a recent study from the United States, "The progression of Pneumocystis carinii pneumonia was...

Oral CMV therapy cost effective.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Oral therapy for cytomegalovirus (CMV) infection is cost-effective. "The overall costs usually are lower for the oral route of administration than for the intravenous route, although the cost to the...

HIV Nef activates macrophage STAT3 via soluble factors.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- HIV Nef activates macrophage STAT3 via soluble factor activity. According to a study from Italy, "Increasing evidence indicates that the expression of the human immunodeficiency virus-1 (HIV-1) Nef...

Macrophages and lymphocytes have differential effects on anti-HIV RANTES activity.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Macrophages and lymphocytes have differential effects on anti-HIV RANTES activity. "The beta-chemokines MIP-1alpha, MIP-1beta, and RANTES inhibit HIV-1 infection of CD4+ T cells by inhibiting...

Nuclear transport of HIV integrase characterized.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- The nuclear transport of HIV integrase has been characterized in human cells. "The human immunodeficiency virus type 1 integrase protein has karyophilic properties; that is, it localizes to the cell...

Opioid-regulated lymphocyte genes identified.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Opioid-regulated lymphocyte genes have been identified. "Morphine was previously found to compromise the chemotactic mobility of leukocytic cells toward inflammatory sites as well as induce the...

PKA signaling underlies gp120-induced T-cell anergy.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- The PKA signaling pathway is involved in the induction of T-cell anergy by HIVenv. According to recent research from Italy, "The ability of the envelope glycoprotein gp120 [human immunodeficiency...

Role of dendritic cell C-type lectin receptors in HIV pathogenesis reviewed.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- The role of dendritic cell C-type lectin receptors in HIV pathogenesis has been reviewed. "Dendritic cells play a major role in HIV pathogenesis," immunologists in Australia explained. "Epithelial...

Incorporating HIV prevention into the medical care of persons living with HIV.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Recommendations for preventing the spread of HIV by HIV-infected individuals have been released in a recent issue of Clinical Infectious Diseases. According to recent research from the United...

Nuclear targeting of HIV Rev transport signals clarified.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- The nuclear targeting activities of the HIV Rev transport signals have been elucidated. "The human immunodeficiency Rev protein shuttles between the nucleus and cytoplasm, while accumulating to high...

Transmission risk data lacking in HIV/AIDS surveillance system.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Information on transmission risk is not being routinely reported to the HIV/AIDS surveillance system. According to a study from the United States, "Risk behavior information is essential for...

Phototherapy ameliorates nanobacteria-related peripheral neuropathy.
February 9, 2004... 2004 FEB 9 - (NewsRx.com & NewsRx.net) -- Phototherapy can ameliorate nanobacteria-induced nerve damage. "Peripheral neuropathy is a common condition in HIV-positive patients and is often experienced in diabetes mellitus," scientists in...