AIDS Weekly articles from February 1994

AIDS Weekly archives from February 1994

Study finds HTLV-1 can mask HIV. (Brazil)
February 7, 1994... Brazil HTLV-1 can mask an important measure of the severity of HIV infections and make those who have the virus get sick faster, a new study found. HTLV-I, is relatively rare in the United States. But it has a higher-than-average...

AIDS survivors studied. (United States)
February 7, 1994... United States Why does HIV kill some people much more slowly than others? Early in the brief history of this disease, death seemed to be the only certainty. More than 200,000 Americans have died so far; about 100 more die daily....

Companies agree to terminate VaxSyn HIV-1 license arrangements. (Wyeth-Ayerst Laboratories and MicroGeneSys)
February 7, 1994... Wyeth-Ayerst Laboratories and MicroGeneSys Wyeth-Ayerst Laboratories, Radnor, Pennsylvania, a division of American Home Products Corporation, and MicroGeneSys Inc., Meriden, Connecticut, announced that they are negotiating the terms on...

Radiation test scare may hurt AIDS vaccine research. (Vanderbilt University)
February 7, 1994... A Vanderbilt University, Nashville, Tennessee, researcher fears reports about radiation experiments on humans are hurting efforts to recruit volunteers for an AIDS study. "Is society going to give up science altogether because of...

New United Nations program on AIDS administered. (World Health Organization)
February 7, 1994... WHO In a resolution, the Executive Board of the World Health Organization (WHO), meeting in Geneva, Switzerland, has recommended the establishment of a cosponsored United Nations (U.N.) program on HIV/AIDS. The aim of the program is to...

100,000 HIV infections by 2000, says official. (China)
February 7, 1994... China China's AIDS problem is worse than official figures suggest, and as many as 100,000 Chinese could be HIV -positive by the end of the century, an official newspaper reported. The People's Daily (Renmin Ribao) said tests of 2.3...

Continent braces itself for surge in HIV cases. (Asia)
February 7, 1994... Asia The fastest spread of AIDS in 1993 was seen in Asia. North America and Europe have managed to slow their rates of new infections, but the number of sufferers is still climbing. Steven Kraus, a World Health Organization (WHO)...

Government reports almost 6,000 cases of HIV infection. (Burma)
February 7, 1994... Burma Nearly 6,000 people in Burma have been diagnosed as being infected with HIV, and there are 133 confirmed cases of people with advanced disease, state-run Rangoon Radio said. Those numbers are only a fraction of estimates by...

Country has more than half of all Central American AIDS cases. (Honduras)
February 7, 1994... Honduras A World Health Organization (WHO) report shows that Honduras has 3,193 of the 5,600 reported AIDS cases in Central America, though the country has only 17 percent of the region's population. Delia Tercero of the Honduran...

Free access to electronic AIDS information. (U.S. National Institutes of Health)
February 7, 1994... U.S. NIH The U.S. National Library of Medicine (NLM), Bethesda, Maryland, has eliminated all online charges for searching three AIDS-related databases and an online directory of sources of information. The action, effective immediately,...

Researcher says exercise helps AIDS patients. (East Tennessee State University)
February 7, 1994... East Tennessee State University Regular exercise can help AIDS patients physically and mentally, an East Tennessee State University researcher says. "What we're really talking about is moderate amounts of exercise," said Dr. J....

New study may enhance understanding of resistance to HIV infection. (Tennessee)
February 7, 1994... Tennessee A study published in the January 1994 issue of AIDS Research and Human Retroviruses conducted by Dr. J. Victor Garcia of St. Jude Children's Research Hospital in Memphis, Tennessee, and Dr. Dusty Miller of Fred Hutchinson...

Fourth person infected with HIV by dentist settles lawsuit. (Florida)
February 7, 1994... Florida The fourth of six people infected with HIV by a Florida dentist has settled a lawsuit with an insurance company that referred her to the dentist. The settlement was reached between the plaintiff and Cigna Dental Health of...

Controversy heats up over subway's safer sex ads. (New York)
February 7, 1994... New York The controversy over explicit AIDS-prevention posters appearing in New York City's subways heated up with opponents and supporters of the advertisements squaring off in the New York City Council. Advocates of the unpaid...

Studies back needle exchanges. (Beth Israel Medical Center)
February 7, 1994... Beth Israel Medical Center Two new studies add to growing evidence that drug addicts will readily accept programs to trade used syringes for clean ones, thus reducing their risk of catching HIV. The studies are important because...

Syringe exchange program does not encourage drug abuse. (California)
February 7, 1994... California In evaluating an all-volunteer syringe exchange program in San Francisco, California, researchers found their data did not support the hypothesis that such an exchange program would stimulate increased drug abuse. John...

HIV seroprevalence among injecting drug users may not remain stable. (New York)
February 7, 1994... New York For almost a decade, HIV seroprevalence has remained stable among a population of injecting drug users (IDUs) at a New York City hospital-based drug abuse detoxification program, reported New York researchers. If current...

Imreg-1 in clinical trials. (immunotherapy for AIDS/HIV) (Imreg Inc.)
February 7, 1994... Imreg Inc. Imreg Inc., New Orleans, Louisiana, released the following statement: Imreg Inc., has received numerous inquiries concerning the present status of Imreg-1 and its relationship to various initiatives pertaining to the...

HIV immune responses in exposed healthcare workers studied. (U.S. National Institutes of Health)
February 7, 1994... U.S. NIH Exposure to HIV with no evidence of subsequent infection appears to result in activation of cellular immunity without activation of antibody production, concluded researchers from the U.S. National Institutes of Health (NIH),...

Corrections officials neglecting health issues, critics say. (Indiana)
February 7, 1994... Indiana Corrections officials in Indiana are simply ignoring the spread of AIDS, tuberculosis (TB) and other infectious diseases, critics charge. The state has failed to take actions recommended by leading health and corrections...

Rapid AIDS spread scares leaders. (Kenya)
February 7, 1994... Kenya The authorities in Kenya have expressed concern about the rapid spread of AIDS in the country. Kenya's HIV-positive population is expected to increase from about 500,000 in 1991 to almost 1.3 million by 1996, according to the...

The coming Himalayan AIDS explosion. (Nepal)
February 7, 1994... Nepal For generations, impoverished Himalayan farmers from Nepal have sent their children down to India to work -their sons as soldiers and their daughters as prostitutes. But while the cash has helped feed and clothe families back...

Herbs and HIV: the health food industry's answer. (Research Report) (Abstract)
February 7, 1994... AUTHORS: L. Phillips, M. Nichols and W. King. University of Alabama, Birmingham, Alabama. According to an abstract submitted by the authors to a joint conference sponsored by the Southern Society For Clinical Investigation, Southern...

Nef causes transcriptional activation of the HIV-1 LTR and cytostasis in macrophages. (Research Report) (Abstract)
February 7, 1994... AUTHORS: K.M. Murphy, M.J. Sweet, I.L. Ross and D.A. Hume. University of Queensland, Centre for Molecular Biology and Biotechnology, Queensland, Australia. According to an abstract submitted by the authors to the 2nd International...

Susceptibility of freshly isolated monocytes, compared with monocyte-derived macrophages to in vitro infection with HIV-1. (Research Report) (Abstract)
February 7, 1994... AUTHORS: A. Maerz, S. Sonza and S. Crowe. Macfarlane Burnet Centre for Medical Research, Fairfield, Victoria. According to an abstract submitted by the authors to the 2nd International Workshop on HIV and Cells of Macrophage Lineage,...

Dysregulation of cytokine expression in monocytes from HIV+ individuals. (Research Report) (Abstract)
February 7, 1994... AUTHORS: J.L. Lathey 1, S. Kanangat 2, B.T. Rouse 2 and S.A. Spector 1. University of California at San Diego, La Jolla California; 2University of Tennessee, Knoxville Tennessee. According to an abstract submitted by the authors to the...

Activation of cytokine genes in tat transfected T- and B-cell lines: differential regulation of TNF-beta, GM-CSF, IL-4 and IL-8. (tumor necrosis factor, granulocyte-macrophage colony-stimulating factor, interleukin) (Research Report) (Abstract)
February 7, 1994... AUTHORS: V. Sharma, T.J. Knobloch and D. Benjamin. Ohio State University, Division of Hematology/Oncology, Columbus, Ohio. According to an abstract submitted by the authors to the Thirty-Fifth Annual Meeting of the American Society of...

Production of IL-beta and sCD23 by human B lymphocytes cooperative effects of HIV-1 and EBV. (interleukin, Epstein-Barr virus) (Research Report) (Abstract)
February 7, 1994... AUTHORS: R. Berger, G. Laux and D. Schwarzmeier. University of Vienna, L. Boltzmann Institute for Cytokine Research, Vienna, Austria. According to an abstract submitted by the authors to the Thirty-Fifth Annual Meeting of the American...

Recognition of mutant tRNAlys by HIV-1 reverse transcriptase. (Research Report) (Abstract)
February 7, 1994... AUTHORS: X. Li, R. Lau, T. Yen, C. Ruland, D. Stephens and J. Rosenblatt. University of California, AIDS Institute, Los Angeles, California. According to an abstract submitted by the authors to the Thirty-Fifth Annual Meeting of the...

Spontaneous onset of inhibitory cytokines mediate suppression of precursor cell function and regulate apoptosis in the bone-marrow of HIV-1-infected patients. (Research Report) (Abstract)
February 7, 1994... AUTHORS: R. Rossol 1, A.S. Klein 1, G. Geissler 1, S. Rossol 2 and D. Hoelzer 1. 1Johann-Wolfgang Goethe University, Department of Hematology, Frankfurt, Germany; 2University Hospital Mannheim, Department Internal Medicine, Mannheim, Germany....

Zidovudine (AZT)-induced anemia related to down regulation of transcripts of erythropoietin receptor (EPO-R), beta-protein kinase C (PKC) and c-fos. (Research Report) (Abstract)
February 7, 1994... AUTHORS: K.C. Agrawal, B.J. Rider, C.A. Leissinger and S.R. Gogu. Tulane University, Departments of Pharmacology and Medicine, New Orleans, Louisiana. According to an abstract submitted by the authors to the Thirty-Fifth Annual Meeting...

HIV-specific T-helper activity in seronegative health care workers exposed to contaminated blood. (Periodical Report) (Abstract)
February 7, 1994... SOURCE: Journal of the American Medical Association, January 5, 1994;271(1):42-46. According to the authors' abstract of an article published in the Journal of the American Medical Association, "Objective: To evaluate human...

Changes in the spectrum of disease in patients hospitalized with HIV infection. (Periodical Report) (Abstract)
February 7, 1994... SOURCE: Medicina Clinica, December 4, 1993;101(19):736 -740. According to the authors' abstract of an article published in Medicina Clinica, "Background: Infections in subjects with HIV-1 infection are a frequent cause of hospital...

Bacterial pneumonia in adult populations with human immunodeficiency virus (HIV) infection. (Periodical Report) (Abstract)
February 7, 1994... SOURCE: American Journal of Epidemiology, December 1, 1993;138(11):909-922. According to the authors' abstract of an article published in the American Journal of Epidemiology, "Recurrent bacterial pneumonia was recently added to the...

Changes in survival after acquired immunodeficiency syndrome (AIDS) - 1984-1991. (Periodical Report) (Abstract)
February 7, 1994... SOURCE: American Journal of Epidemiology, December 1, 1993;138(11):952-964. According to the authors' abstract of an article published in the American Journal of Epidemiology, "In a prospective cohort of 2,647 human immunodeficiency...

Long-term inhibition of clinical and laboratory human immunodeficiency virus strains in human T-cell lines containing an HIV-regulated diphtheria toxin-A chain gene. (Periodical Report) (Abstract)
February 7, 1994... SOURCE: Human Gene Therapy, December 1993;4(6):741-747. According to the authors' abstract of an article published in Human Gene Therapy, "The human immunodeficiency virus (HIV) causes persistent infection of T cells. Chemotherapy...

Patient attitudes toward rooming with persons with HIV infection. (Periodical Report) (Abstract)
February 7, 1994... SOURCE: Journal of Family Practice, December 1993;37(6):564-568. According to the authors' abstract of an article published in the Journal of Family Practice, "Background: Early in the HIV epidemic, hospitals developed strict...

V3 variability can influence the ability of an antibody to neutralize or enhance infection by diverse strains of human immunodeficiency virus type-1. (Periodical Report) (Abstract)
February 7, 1994... SOURCE: Proceedings of the National Academy of Sciences of the United States of America, December 15, 1993;90(24):11518-11522. According to the authors' abstract of an article published in Proceedings of the National Academy of...

President names panel to speed search for HIV drug. (Bill Clinton) (Washington, D.C.)
February 14, 1994... Washington, D.C. The Clinton administration named an 18-member panel of scientists, doctors and AIDS activists to help speed the search for new drugs to combat HIV. The panel includes pharmaceutical industry executives as well as...

Thousands rally in London to lower the age of consent for gays. (United Kingdom)
February 14, 1994... United Kingdom Thousands gathered in London's Trafalgar Square to demonstrate their support for lowering the age of consent for homosexual men in Britain from 21 to 16. During the last few weeks, gay rights campaigners and medical...

Survey finds national differences in condom use. (Europe)
February 14, 1994... Europe A survey released in Paris, France, February 3, 1994, reveals national differences in condom use among European men. For instance, Spanish men used an average of 3.8 condoms each in 1992, as compared with 2.7 used by British...

Trials of the first globally targeted AIDS vaccine begin. (United Biomedical Inc.)
February 14, 1994... United Biomedical Inc. United Biomedical Inc. (UBI), Hauppauge, New York, has begun clinical trials of the first multicomponent synthetic AIDS vaccine designed specifically to address the extensive worldwide variability of HIV-1. ...

Zidovudine resistance persists after therapy discontinued. (University of North Carolina)
February 14, 1994... University of North Carolina A report from a North Carolina research facility suggests that zidovudine-resistant HIV appears to persist and replicate well in vivo after discontinuation of zidovudine therapy. The emergence of...

Combined zidovudine/didanosine shows enhanced activity. (U.S. National Cancer Institute)
February 14, 1994... U.S. NCI Simultaneous therapy with zidovudine and didanosine (ddI) provided more sustained elevations in CD4 cells than alternating therapy with the agents over a one-year period, according to a report from the U.S. National Cancer...

HIV immune responses in exposed healthcare workers studied. (U.S. National Institutes of Health)
February 14, 1994... U.S. NIH Exposure to HIV with no evidence of subsequent infection appears to result in activation of cellular immunity without activation of antibody production, concluded researchers from the U.S. National Institutes of Health (NIH),...

Conference set to explore diagnosis and management of TB. (tuberculosis) (New York)
February 14, 1994... New York Physicians, scientists and government and public health officials will explore potential solutions to diagnosing and managing tuberculosis (TB) during a special conference scheduled March 1, 1994. The conference will be...

Condom use varies depending on nature of relationship. (United Kingdom)
February 14, 1994... United Kingdom British researchers found an overall increase in condom use among gay and bisexual men over time, but noted significant differences depending on the nature of the partner, whether casual or regular ("Changes in Condom Use...

HIV cutting lives short in hemophilia, study says. (U.S. Centers for Disease Control)
February 14, 1994... U.S. CDC The life span of people with the most common kind of hemophilia has plunged 30 percent to levels like those of more than two decades ago, before modern treatment was available. The key reason: AIDS. "Sadly, we've taken a...

Man accuses Gay Men's Health Crisis of discrimination. (James Fielding) (New York)
February 14, 1994... New York James Fielding says going to work at Gay Men's Health Crisis (GMHC), New York, is more important to him than taking his medicine. But Fielding, who suffers from AIDS, is suing the organization on the grounds that it...

Law proposed to make intentional passing of HIV illegal. (Colorado)
February 14, 1994... Colorado A bill that would make it possible to prosecute officials of hospitals, blood banks and individuals for intentionally exposing people to HIV has been introduced by Representative Drew Clark, Republican-Boulder. The...

2 million in Asia infected with HIV. (World Health Organization)
February 14, 1994... WHO About 2 million Asians have been infected with HIV, and Asia is expected to suffer the fastest spread of the infection in coming years, a World Health Organization (WHO) official said. The world total for people infected with...

AIDS hotline goes broke. (China)
February 14, 1994... China An AIDS telephone hotline in China's highest HIV-risk province has run out of money, prompting the director to suggest auctioning it, a state-run newspaper reported. Volunteer medical students and personnel established the...

North American Biologicals acquires major plasma provider. (Premier BioResources Inc.) (Florida/Texas)
February 14, 1994... Florida/Texas North American Biologicals Inc., Miami, Florida, (NABI) reported the completion of its acquisition, initially announced on January 26, 1994, of Premier BioResources Inc. (PBI) of Ft. Worth, Texas, in a transaction that is...

Red blood cell/CD4 therapy topic of meeting with FDA. (Food and Drug Administration) (Sheffield Medical Technologies Inc.)
February 14, 1994... Sheffield Medical Technologies Inc. Sheffield Medical Technologies Inc., Houston, Texas, announced that on February 2, 1994, representatives of the company met with representatives of the U.S. Food and Drug Administration (FDA) regarding...

Kenan Institute to manage development partnership. (Kenan Institute of Private Enterprise) (Thailand)
February 14, 1994... Thailand The U.S. and Thai governments announced in Bangkok, Thailand, a new "Development Partnership" between the countries. The agreement is designed to sustain economic cooperation on a more efficient, mutually beneficial basis as...

Surgeon is believed to have infected four surgical patients with HIV. (Australia)
February 14, 1994... Australia Four women in Australia are believed to have been infected with HIV during surgery (See Also AIDS Weekly***). An investigation revealed what was termed compelling evidence that the women were infected with HIV during minor...

New formula provides better nutritional management. (California)
February 14, 1994... California A new enterotropic peptide-based formula provides superior nutritional management in HIV-infected patients, compared to the standard enteral formula, according to a recent study ("Long-Term Effects of Early Nutritional Support...

New symptom checklist is valid measure of HIV disease status. (Riverside Symptom Checklist) (United Kingdom)
February 14, 1994... United Kingdom The Riverside Symptom Checklist (RSC) of HIV infection has proven to be a reliable and valid measure of subjective health status among the HIV infected, according to a recent report ("The Reliability and Validity of a...

Replication rate and tropism correlate with HIV/AIDS progression. (Italy)
February 14, 1994... Italy High replicating and cytopathic T-lymphotropic variants of HIV-1 play a role in the progression of HIV/AIDS among infants who have vertically acquired the infection, according to a report from the University of Padua and the...

Randomized comparative study of itraconazole (ITR) and fluconazole (FLU) for treatment of AIDS-related cryptococcal meningitis (CM). (Research Report)
February 14, 1994... AUTHORS: B.L. Moskovitz, B. Wiesinger. Cryptococcal Meningitis Research Group; Janssen Research Foundation, Titusville, New Jersey. According to an abstract submitted by the authors to the First National Conference on Human Retroviruses...

Native oligomeric forms of HIV-1 envelope glycoprotein elicit a diverse array of monoclonal antibody reactivities. (Research Report)
February 14, 1994... AUTHORS: P.L. Earl 1, C.C. Broder 1, D. Long 2, R.W. Doms 2 and B. Moss 1. 1U.S. National Institute of Allergy and Infectious Diseases, Bethesda, Maryland; 2University of Pennsylvania, School of Medicine, Philadelphia, Pennsylvania. ...

Valency, reversibility, and the state of the virion determine in vitro HIV-1 V3-specific neutralization efficacy. (Research Report)
February 14, 1994... AUTHORS: M.J. Merges 1, S.P. Layne 2, J.L. Spouge 3 and P.L. Nara 1. 1Frederick Cancer Research and Development Center, Frederick, Maryland; 2University of California, School of Medicine, Los Angeles, California; and 3National Library of...

A broadly-reactive anti-V3 gp120 human monoclonal antibody effectively neutralizes primary HIV-1 isolates. (Research Report)
February 14, 1994... AUTHORS: A.J. Conley 1, J.A. Kessler II 1, L.J. Boots 1, D. Lineberger 1, W.A. Schleif 1, E.A. Emini 1, M. Ossorio 2, G. Bansal 2, S. Koenig 2, M. Gorny 3, C. Williams 3, S. Zolla-Pazner 3. 1Merck Research Laboratories, West Point,...

Chimeric minigenes: induction of heterogenous CTL. (cytotoxic T lymphocytes) (Research Report)
February 14, 1994... AUTHORS: C.C. Bergmann and S.A. Stohlman. University of Southern California, School of Medicine, Los Angeles, California. According to an abstract submitted by the authors to the First National Conference on Human Retroviruses and...

Increase survival of immunodeficient retrovirus infected mice (MAIDS) treated with lithium. (Research Report)
February 14, 1994... AUTHORS: V.S. Gallicchio, M.L. Cibull, N.K. Hughes and K.F. Tse. University of Kentucky, Medical Center, Lexington, Kentucky. According to an abstract submitted by the authors to the 2nd International Workshop on HIV and Cells of...

HIV replication in chronically infected macrophages is not inhibited by Tat inhibitors Ro-5-3335 and Ro-24-7429. (Research Report)
February 14, 1994... AUTHORS: A. Durme, H. Siregar, S. Sonza and S. Crowe. Macfarlane Burnet Center for Medical Research, Fairfield, Victoria. According to an abstract submitted by the authors to the 2nd International Workshop on HIV and Cells of Macrophage...

Monoclonal antibody to the 25E epitope of Mac-1 significantly enhances cluster formation by HIV-infected monocytes especially in the presence of interleukin 4 (IL-4). (Research Report)
February 14, 1994... AUTHORS: J. Chang 1, S. Li 1, F. Kazazi 2, G. Burns 3 and A. Cunningham 1. 1Westmead Hospital, Centre for Infectious Diseases and Microbiology, Sydney, Australia; 2University of Washington, Division of Allergy and Infectious Diseases,...

Idiopathic esophageal ulceration in the acquired immunodeficiency syndrome - radiologic reappraisal in 10 patients. (Periodical Report) (Abstract)
February 14, 1994... SOURCE: Abdominal Imaging, January-February 1994;19(1):2-5. According to the authors' abstract of an article published in Abdominal Imaging, "Idiopathic esophageal ulceration in patients with AIDS has previously been described....

Cell-based and biochemical analysis of the anti-HIV activity of combinations of 3'-azido-3'-deoxythymidine and analogues of TIBO. (Periodical Report) (Abstract)
February 14, 1994... SOURCE: Antiviral Chemistry & Chemotherapy, January 1994;5(1):35-42. According to the authors' abstract of an article published in Antiviral Chemistry & Chemotherapy, "The toxicity of 3'-azido-3'-deoxythymidine (AZT) and the...

Cross-resistance between AZT, ddI and other retroviral drugs in primary isolates of HIV-1. (Periodical Report) (Abstract)
February 14, 1994... SOURCE: Antiviral Chemistry & Chemotherapy, January 1994;5(1):7-12. According to the authors' abstract of an article published in Antiviral Chemistry & Chemotherapy, "Primary isolates of human immunodeficiency virus type 1 (HIV-1)...

Drug combination of AZT and ddI - synergism of action and prevention of appearance of AZT-resistance. (zidovudine, didanosine) (Periodical Report) (Abstract)
February 14, 1994... SOURCE: Antiviral Chemistry & Chemotherapy, January 1994;5(1):51-55. According to the authors' abstract of an article published in Antiviral Chemistry & Chemotherapy, "Both 3'-azido-3'-deoxythymidine (AZT) and 2',3'-dideoxyinosine...

AIDS from an oncological viewpoint - paradoxical immunodeficiency by helper T-cell proliferation and senescence - review. (Periodical Report) (Abstract)
February 14, 1994... SOURCE: International Journal of Oncology, January 1994;4(1):101-107. According to the authors' abstract of an article published in the International Journal of Oncology, "Autoimmunity due to human immunodeficiency disease virus (HIV-1)...

Development of an in vitro model of Toxoplasma gondii cyst formation. (Periodical Report) (Abstract)
February 14, 1994... SOURCE: FEMS Microbiology Letters, December 15, 1993;114(3):325-332. According to the authors' abstract of an article published in FEMS Microbiology Letters, "Toxoplasma gondii tissue cyst reactivation is a major pathogenic...

Infection with the human immunodeficiency virus in prisoners - meeting the health care challenge. (Periodical Report) (Abstract)
February 14, 1994... SOURCE: American Journal of Medicine, December 1993;95(6):629-635. According to the authors' abstract of an article published in the American Journal of Medicine, "The magnitude and the scope of health care problems posed by human...

Hybrid AIDS virus tested at baboon center. (Texas)
February 21, 1994... DATELINE: Texas San Antonio, Texas, scientists have successfully infected two baboons with a hybrid human-monkey AIDS virus, providing them another animal model with which an AIDS vaccine might be developed. Researchers at Southwest...

Trials in HIV patients begin. (drug trials)(Synovir)(Celgene Corporation)
February 21, 1994... DATELINE: Celgene Corporation Celgene Corporation, Warren, New Jersey, announced that it has entered into a clinical collaboration with the U.S. National Institute of Allergy and Infectious Diseases (NIAID), of the U.S. National...

Trial of OPC-8212 to begin. (drug trial)(Georgia)
February 21, 1994... DATELINE: Georgia A clinical trial of the Japanese drug, OPC-8212, will begin in Atlanta, Georgia, in February 1994. The drug, manufactured by Otsuka America Pharmaceuticals, inhibits substances associated with the replication of...

Pharmaceutical companies reinforce partnership to combat AIDS. (World Health Organization)
February 21, 1994... DATELINE: WHO Research based pharmaceutical companies represented by the International Federation of Pharmaceutical Manufacturers Associations (IFPMA) have agreed to work with the World Health Organization (WHO) in the effort to resolve...

BioChem Pharma and Glaxo extend research agreement. (British Columbia)
February 21, 1994... DATELINE: British Columbia BioChem Pharma Inc. and Glaxo Canada Inc. signed a letter of intent extending their Research Agreement in the antiviral field for a two-year period. The Agreement remains in effect until December 31, 1996, and...

Recently discovered bacterial disease linked to cats. (bacillary angiomatosis caused by Rochalimaea henselae)(University of California, San Francisco)
February 21, 1994... DATELINE: University of California, San Francisco Stressing they do not suggest that people avoid cats, researchers at University of California, San Francisco (UCSF), say that some patients with a rare and recently recognized bacterial...

Syntello acquires broad rights to mucosal vaccine. (cholera toxin B mucosal vaccine carrier)(California)
February 21, 1994... DATELINE: California Syntello Inc., San Diego, California, has acquired exclusive rights to apply and license the Cholera Toxin B (CTB) mucosal vaccine carrier, developed by Dr. Jan Holmgren at the University of Gothenburg, Sweden. The...

Company awarded $750,000 NIH grant for antifungal drug research. (Myco Pharmaceuticals Inc.;National Institutes of Health)(Massachusetts)
February 21, 1994... DATELINE: Massachusetts Myco Pharmaceuticals Inc. announced that the company and its collaborators have been awarded by the U.S. National Institutes of Health (NIH) a grant for over $750,000 to fund antifungal drug research. The grant,...

Plasma immunotherapy affected by presence of p24 antibody. (California)
February 21, 1994... DATELINE: California The potential benefits of plasma immunotherapy in the treatment of pediatric AIDS may depend on specific p24 antibody, according to a recent report ("Plasma Immunotherapy in a Child with Acquired Immunodeficiency...

Transfusions to HIV-infected patients results in increased death rate. (U.S. National Heart, Lung and Blood Institute)
February 21, 1994... DATELINE: U.S. National Heart, Lung and Blood Institute HIV-infected patients who received transfusions showed increased incidence of cytomegalovirus (CMV) infection and increased death rate, stated researchers from the U.S. National...