AIDS Weekly articles from August 1994

AIDS Weekly archives from August 1994

Tenth AIDS conference to open in Yokohama, Japan. (X International Conference on AIDS)
August 8, 1994... DATELINE: X International Conference on AIDS The tenth anniversary meeting of the world AIDS community will open August 7, 1994, in Yokohama, Japan, in an era of diminished expectations. Hopes for miracle cure have given way to...

Baboon model enables test of treatments for immune cell survival.
August 8, 1994... DATELINE: X International Conference on AIDS At a scientific session commemorating the tenth anniversary of the discovery of HIV, an AIDS researcher from the University of California, San Francisco (UCSF), announced an animal model for...

Study examines sexual attitudes and coercion among U.S. Latino males.
August 8, 1994... DATELINE: X International Conference on AIDS "Sexual silence" and sexual coercion among U.S. Latino adults may contribute to the HIV epidemic in the Latino community, according to University of California, San Francisco (UCSF),...

Fluconazole resistance increasingly common among HIV positives.
August 8, 1994... DATELINE: Candidosis Clinical failure of fluconazole is an increasingly significant problem among HIV-positive patients who have recurrent problematic mucosal candidosis (candidiasis), according to a report from the United Kingdom. ...

ISCOM vaccine strategy protects monkeys against HIV-2. (immunostimulating complex)
August 8, 1994... DATELINE: HIV Vaccines Immunization of monkeys with two different immunostimulating complex (ISCOM) formulations protected three of four animals against challenge with cell-free HIV*2, Swedish researchers report. ISCOMs are...

Mucosal immunization possible in moderately advanced AIDS.
August 8, 1994... DATELINE: Mucosal Immunity A study of British men and Kenyan women indicates that mucosally targeted vaccines are potentially useful even in the relatively late stages of HIV disease. Debilitating gastrointestinal infections...

Caesareans may lower HIV risk.
August 8, 1994... DATELINE: Risk Pregnant women with HIV who experience complications during delivery may have slightly better chances of delivering healthy babies if they quickly undergo a Caesarean section, a study suggests. Doctors believe most...

AIDS study prejudice charged. (discrimination against women in trials of AIDS drugs)
August 8, 1994... DATELINE: Controversy U.S. government regulators allow scientists to discriminate against women in trials of promising AIDS drugs, even demanding they be sterilized if they want to participate, a lawyer asserted. The U.S. Food and...

Oral device used in detecting antibodies. (Epitope Inc.'s OraSure oral specimen collection device)
August 8, 1994... DATELINE: Study Epitope Inc., Beaverton, Oregon, reported that a study published in the July 20, 1994, issue of the Journal of the American Medical Association (JAMA) shows that specimens collected using the OraSure oral specimen...

Plans for protocol in AIDS human trial. (VIMRx Pharmaceuticals Inc.'s hypericin clinical trial)
August 8, 1994... DATELINE: Clinical Trial VIMRx Pharmaceuticals Inc., Stamford, Connecticut, announced that the current Phase I/II human clinical trial (ACTG 258) for the oral dosing of hypericin has demonstrated sustained reduction in plasma viremia in...

Biocine begins Phase I clinical trials of CMV vaccine. (cytomegalovirus)
August 8, 1994... DATELINE: Vaccines Chiron Corporation, Emeryville, California, announced that the Biocine Company, a joint venture with Ciba-Geigy Ltd., Basel, Switzerland, has begun Phase I clinical trials of a candidate cytomegalovirus (CMV)...

Healthcare providers take lead in AIDS managed care project. (Midway Hospital Medical Center, Country Villa Service Corp.)
August 8, 1994... DATELINE: Joint Venture Midway Hospital Medical Center and Country Villa Service Corporation are the first two Los Angeles healthcare providers to announce their participation in the AIDS managed care program being developed by the Los...

Three cases of superinfection with MDR-TB reported. (multidrug-resistant tuberculosis)
August 8, 1994... DATELINE: Drug Resistance Clinicians at a Bronx treatment center report three cases of multidrug-resistant tuberculosis (MDR-TB) occurring in AIDS patients being treated for drug -susceptible disease. Reinfection with new strains of...

TB risk in HIV positives increased by population. (tuberculosis)
August 8, 1994... DATELINE: Anergy A Spanish study suggests that for every 10 percent increase in the prevalence of TB infection in a given population, the risk of active tuberculosis (TB) in anergic, HIV-infected drug users increases by more than three...

Drug resistance not main barrier to TB control in Zambia. (tuberculosis)
August 8, 1994... DATELINE: Epidemiology Drug resistance is not the principal barrier to effective control of tuberculosis (TB) in Zambia, according to a retrospective review. In sub-Saharan Africa the annual risk of becoming infected with TB is 2...

AIDS patients to undergo ozone/oxygen drug therapy. (Medizone International Inc.)
August 8, 1994... DATELINE: Testing Medizone International Inc., New York, announced that the 60-patient enrollment process has begun by the company's Italian colleagues and that these patients will soon enter the therapy phase of the protocol for the...

Approval for new use of AZT. (usage of Retrovir zidovudine to prevent transmission of HIV from mother to infant)
August 8, 1994... DATELINE: U.S. FDA The U.S. Food and Drug Administration (FDA) Antiviral Drugs Advisory Committee voted unanimously to recommend approval for the use of Retrovir brand zidovudine (AZT) to reduce the risk of HIV transmission from mother...

Thousand new AIDS cases in Thailand.
August 8, 1994... DATELINE: Case Rates More than 1,000 new cases of AIDS were reported in Thailand during the first six months of 1994, the Thai Public Health Ministry reported. A total of 1,146 new advanced AIDS cases, including 980 men and 166...

Rwanda slaughter worsens AIDS.
August 8, 1994... DATELINE: AIDS in Africa Working in Rwanda, Dr. Sergio Improta amputated seven limbs a day, rebuilt a smashed jaw, plucked maggots from gangrenous wounds and tried but failed to save a man with a machete gash so deep his brain was...

Elevated TNF-alpha levels found in Zairian neonate plasma. (tumor necrosis factor)
August 8, 1994... DATELINE: Zaire Elevated plasma tumor necrosis factor-alpha (TNFalpha) levels detected in Zairian newborns may be a factor in the pathogenesis and progression of HIV disease in this patient population, indicated researchers from the U.S....

Sensitivity and specificity of gallium-67 scanning in patients with HIV infection and pulmonary tuberculosis (PTB). (Research Report)
August 8, 1994... AUTHORS: M. Gorla, B.Y. Huang, G. Rodriguez, K.D. Lessnau and W. Talavera. New York Medical College, New York, New York. According to an abstract submitted by the authors to the 1994 International Conference of the American Lung...

Inevitability of death from tuberculosis in the context of HIV/AIDS. (Research Report)
August 8, 1994... AUTHORS: C.A. Mosca, S. Rossi, J. Macias, R, Masini, P.J. Gonzalez-Montaner and L.J. Gonzalez-Montaner. Universidad de Buenos Aires, Buenos Aires, Argentina. According to an abstract submitted by the authors to the 1994 International...

Prevalence of HIV, tuberculin positivity and active TB in an urban Haitian community. (Research Report)
August 8, 1994... AUTHORS: R.E. Chaisson, J. Coberly, M. Cantave, J. Atkinson, H.C. Clermont, M. Voltaire, R. Boulos and N. Halsey. Johns Hopkins University, Baltimore, Maryland; Centres pour le Developpement et pour la Sante, Cite Soleil, Haiti. ...

The epidemiology of HIV-associated tuberculosis in Tanzania. (Research Report)
August 8, 1994... AUTHORS: H.L. Chum 1, P. Graf 2, R. Kitumba 1, R. O'Brien 3 and H. Rieder 3. 1Tanzania National Tuberculosis and Leprosy Program, Dar es Salaam, Tanzania; 2WHO Tuberculosis Program, Geneva, Switzerland; 3International Union Against...

Tuberculin skin testing programs in long-term care facilities for the elderly. (Research Report)
August 8, 1994... AUTHORS: M. McArthur, I.G. Naglie, A. Cheung, A. Simor, M. Naus and A. McGreer. Princess Margaret Hospital, Ontario, Canada; Mount Sinai Hospital, Toronto, Canada; Toronto Hospital, Toronto, Canada; Sunnybrook Health Science Centre, Toronto,...

Tuberculosis and HIV in Sub-Saharan Africa - can a good tuberculosis program make a difference? (Research Report)
August 8, 1994... AUTHORS: M.C. Cantwell and N.J. Binkin. U.S. Centers for Disease Control and Prevention, Division of Tuberculosis Elimination, Atlanta, Georgia. According to a plenary abstract presented by the authors to the conference entitled...

Pulmonary disease in sputum smear negative HIV-infected patients from Africa. (Research Report)
August 8, 1994... AUTHORS: J. Murray 1, S. Klempman 1, A.K. Mahomed 2, G. Richards 2, C. Feldman 2 and J. Kallenbach 2. 1National Center for Occupational Health, Johannesburg, South Africa; and 2University of the Witwatersrand, Johannesburg, South Africa. ...

Delivery of anti-HIV nucleosides to the central nervous system. (Reprinted from Advanced Drug Delivery Reviews, June-July 1994) (Periodical Report) (Abstract)
August 8, 1994... SOURCE: Advanced Drug Delivery Reviews, June-July 1994;14(2-3):199-209. According to the author's abstract of an article published in Advanced Drug Delivery Reviews, "The ability of the human immunodeficiency virus (HIV) to enter...

Improved brain delivery of antiviral agents through the use of redox targeting. (Reprinted from Advanced Drug Delivery Reviews, June-July 1994) (Periodical Report) (Abstract)
August 8, 1994... SOURCE: Advanced Drug Delivery Reviews, June-July 1994;14(2-3):177-197. According to the authors' abstract of an article published in Advanced Drug Delivery Reviews, "The inability to effectively deliver antiviral agents to the...

Mutations in the coding region of c-MYC in AIDS-associated and other aggressive lymphomas. (Reprinted from Cancer Research, July 1, 1994) (Periodical Report) (Abstract)
August 8, 1994... SOURCE: Cancer Research, July 1, 1994;54(13):3383-3386. According to the authors' abstract of an article published in Cancer Research, "Our previous studies of the translocated MYC gene in Burkitt's lymphoma showed the existence of...

Bleach use and HIV seroconversion among New York City injection users. (Reprinted from the Journal of Acquired Immune Deficiency Syndromes, July 1994) (Periodical Report) (Abstract)
August 8, 1994... SOURCE: Journal of Acquired Immune Deficiency Syndromes, July 1994;7(7):700-704. According to the authors' abstract of an article published in the Journal of Acquired Immune Deficiency Syndromes, "We employed a nested case-control...

Cigarette smoking, premature rupture of membranes, and vertical transmission of HIV-1 among women with low CD4+ levels. (Reprinted from the Journal of Acquired Immune Deficiency Syndromes, July 1994) (Periodical Report) (Abstract)
August 8, 1994... SOURCE: Journal of Acquired Immune Deficiency Syndromes, July 1994;7(7):718-726. According to the authors' abstract of an article published in the Journal of Acquired Immune Deficiency Syndromes, "To examine the possible influence of...

Compliance to bleach disinfection protocols among injecting drug users in Miami. (Reprinted from the Journal of Acquired Immune Deficiency Syndromes, July 1994) (Periodical Report) (Abstract)
August 8, 1994... SOURCE: Journal of Acquired Immune Deficiency Syndromes, July 1994;7(7):773-776. According to the authors' abstract of an article published in the Journal of Acquired Immune Deficiency Syndromes, "Bleach cleansing of injection...

Constriction and characterization of a potent HIV-2 tat transdominant mutant protein. (Reprinted from the Journal of Acquired Immune Deficiency Syndromes, July 1994) (Periodical Report) (Abstract)
August 8, 1994... SOURCE: Journal of Acquired Immune Deficiency Syndromes, July 1994;7(7):655-664. According to the authors' abstract of an article published in the Journal of Acquired Immune Deficiency Syndromes, "The human immunodeficiency virus...

Effects of HIV infection on VH3 (D12 idiotope) B cells in vivo. (Reprinted from the Journal of Acquired Immune Deficiency Syndromes, July 1994) (Periodical Report) (Abstract)
August 8, 1994... SOURCE: Journal of Acquired Immune Deficiency Syndromes, July 1994;7(7):641-646. According to the authors' abstract of an article published in the Journal of Acquired Immune Deficiency Syndromes, "The abnormalities of B lymphocytes...

Heterosexual transmission of human immunodeficiency virus type 1 from transfusion recipients to their sex partners. (Reprinted from the Journal of Acquired Immune Deficiency Syndromes, July 1994) (Periodical Report) (Abstract)
August 8, 1994... SOURCE: Journal of Acquired Immune Deficiency Syndromes, July 1994;7(7):705-710. According to the authors' abstract of an article published in the Journal of Acquired Immune Deficiency Syndromes, "Using lookback procedures and other...

Induction of neutralizing antibodies against human immunodeficiency virus type 1 using synthetic peptide constructs containing an immunodominant T-helper cell determinant from vpr. (Reprinted from the Journal of Acquired Immune Deficiency Syndromes, July 1994) (Periodical Report) (Abstract)
August 8, 1994... SOURCE: Journal of Acquired Immune Deficiency Syndromes, July 1994;7(7):635-640. According to the authors' abstract of an article published in the Journal of Acquired Immune Deficiency Syndromes, "Identification of immunodominant...

Impact of immunosuppression on health care use by men in the Multicenter AIDS Cohort Study (MACS). (Reprinted from the Journal of Acquired Immune Deficiency Syndromes, June 1994) (Periodical Report) (Abstract)
August 8, 1994... SOURCE: Journal of Acquired Immune Deficiency Syndromes, June 1994;7(6):607-616. According to the authors' abstract of an article published in the Journal of Acquired Immune Deficiency Syndromes, "The effects of human...

Long-standing protection of macaques against cell-free HIV-2 with a HIV-2 iscom vaccine. (Reprinted from the Journal of Acquired Immune Deficiency Syndromes, June 1994) (Periodical Report) (Abstract)
August 8, 1994... SOURCE: Journal of Acquired Immune Deficiency Syndromes, June 1994;7(6):551-559. According to the authors' abstract of an article published in the Journal of Acquired Immune Deficiency Syndromes, "We investigated the capacity of two...

Experts gather to chart AIDS victories and defeats. (X International Conference on AIDS)
August 15, 1994... X International Conference on AIDS The world's leading AIDS experts gathered for their first conference in Asia, where the disease is spreading fastest, to assess the global campaign against the pandemic. Participants say hopes of...

Women's issues move to center stage of AIDS conference. (X International Conference on AIDS)
August 15, 1994... X International Conference on AIDS The urgent message that women's issues are the key to AIDS prevention received special emphasis at the opening plenary session of the X International Conference on AIDS, held August 7-12, 1994, in...

PAP smear study finds procedure comparable to colposcopy. (X International Conference on AIDS)
August 15, 1994... X International Conference on AIDS Early results of a small study of women infected with HIV indicate that using the common Pap smear test to detect potentially precancerous cellular changes in the cervix is comparable in accuracy to...

WHO AIDS chief blasts "denial, discrimination, disempowerment." (World Health Organization, Michael Merson)(X International Conference on AIDS)
August 15, 1994... X International Conference on AIDS The 3 million new HIV infections that have occurred in the last year can be attributed to the failure of national governments to face up to the AIDS pandemic, according to Michael Merson, executive...

Fauci announces findings from study of long-term non-progressors. (Anthony S. Fauci)(X International Conference on AIDS)
August 15, 1994... X International Conference on AIDS Studies of individuals who remain healthy and immunologically normal despite long-term HIV infection have yielded important new insights into the pathogenesis of HIV disease, according to Anthony S....

HIV burden unchecked by antiretroviral therapy in early stage disease. (X International Conference on AIDS)
August 15, 1994... X International Conference on AIDS Antiretroviral therapy has no detectable effect on the amount of HIV in lymphoid tissue or in certain white blood cells of patients with early HIV disease, according to preliminary results from a study...

AZT not recommended for patients with CD4 counts above 500. (X International Conference on AIDS)
August 15, 1994... X International Conference on AIDS Researchers have found that giving the anti -retroviral drug zidovudine - also called AZT - to patients with CD4 counts above 500 cells/mm(3) does not further extend their lives or keep their HIV...

Study of oral treatment to prevent CMV disease launched. (cytomegalovirus)(X International Conference on AIDS)
August 15, 1994... X International Conference on AIDS The largest study to date of treatment to prevent one of the most serious opportunistic infections acquired by HIV-infected persons has enrolled 995 volunteers at 16 sites across the US. The multicenter...

HIV vaccine stimulates broadened immune response. (X International Conference on AIDS)
August 15, 1994... X International Conference on AIDS An investigational HIV vaccine under study at St. Louis University School of Medicine, Missouri, and two other U.S. sites caused no major side effects and produced a broader immune response than has been...

Results from RGP160 European trial at Yokohama AIDS conference. (AIDS vaccine)(X International Conference on AIDS)
August 15, 1994... X International Conference on AIDS Immuno rgp160 induced T-cell memory, an important aspect of immunity, in two groups of HIV-positive volunteers, one group with CD4 counts above 500, and another with CD4 counts between 200 and 500. No...

Chimpanzee vaccine model protects against HIV-1 infection. (X International Conference on AIDS)
August 15, 1994... X International Conference on AIDS New data from studies in chimpanzees show that development of a protective vaccine using an inactivated or weakened form of whole HIV-1, may be possible, according to scientists from the U.S. National...

Finding new inhibitors of the HIV-1 integrase. (X International Conference on AIDS)
August 15, 1994... X International Conference on AIDS Scientists at the U.S. National Cancer Institute (NCI) are searching for novel anti-AIDS drugs that block the activity of HIV integrase, the protein that HIV uses to integrate its DNA into the DNA of...

Therapy with AZT and ddI for HIV patients. (X International Conference on AIDS)
August 15, 1994... X International Conference on AIDS AZT and ddI are initially more effective in suppressing the replication of HIV-1 when they are given simultaneously to patients with advanced HIV infection than when they are administered in an...

Five-year follow-up of study of ddI in patients with advanced HIV infection. (X International Conference on AIDS)
August 15, 1994... X International Conference on Aids Patients with moderately advanced HIV infection had encouraging long-term survival trends on didanosine (ddI)-based therapy, a study by U.S. National Cancer Institute (NCI) researchers has shown. ...

Five new Wellcome anti-HIV drugs announced. (Wellcome plc, British pharmaceutical company)(X International Conference on AIDS)
August 15, 1994... X International Conference on AIDS British pharmaceutical company Wellcome plc announced on August 7, 1994, at the X International Conference on AIDS in Yokohama, Japan, that it has five new anti-HIV compounds in development. "It is...

Mechanisms of HIV-envelope glycoprotein-mediated membrane fusion. (X International Conference on AIDS)
August 15, 1994... X International Conference on AIDS Researchers at the U.S. National Cancer Institute (NCI), the U.S. National Institute of Allergy and Infectious Diseases, and the U.S. Food and Drug Administration can now measure the fusion of HIV with...

AIDS conference attendees from 128 countries. (X International Conference on AIDS)
August 15, 1994... X International Conference on AIDS The world's press - 1,780 registered media representatives including four from CW Henderson, Publisher publications - descended on Yokohama, Japan, August 7-12, 1994. Registered participants at the...

For healthcare workers with TB, no association with occupation. (tuberculosis)(X International Conference on AIDS)
August 15, 1994... X International Conference on AIDS In a report presented by officials of the U.S. Centers for Disease Control and Prevention (CDC) to the X International Conference on AIDS, held in Yokohama, Japan, August 7-12, 1994, no clear association...

AIDS patients increasingly at risk for hospital-acquired infections. (X International Conference on AIDS)
August 15, 1994... X International Conference on AIDS AIDS patients are at risk for nosocomial infections, according to a presentation at the X International Conference on AIDS in Yokohama, Japan, held August 7-12, 1994. Bienvenido G. Yangco of St....

Nosocomial outbreak of MDR-TB detected in Italy. (multidrug-resistant tuberculosis)(X International Conference on AIDS)
August 15, 1994... X International Conference on AIDS A further spread of multidrug resistant tuberculosis (MDR-TB) is predicted in Italy, according to research presented to the X International Conference on AIDS, held in Yokohama, Japan, August 7-12,...

AIDS is a leading cause of death among young men in Italy. (X International Conference on AIDS)
August 15, 1994... X International Conference on AIDS In many Italian communities, AIDS is the leading cause of death among young men, causing a large proportion of death in the 25 to 44 age group. This is the grim finding presented by Susanna Conti...

Recently ended pregnancy associated with lower risk of TB. (tuberculosis)(X International Conference on AIDS)
August 15, 1994... X International Conference on AIDS Recently ended pregnancy is associated with a lower risk of tuberculosis (TB), according to a study presented to the X International Conference on AIDS held in Yokohama, Japan, August 7-12, 1994. ...

Haircuts and AIDS education go together in India. (X International Conference on AIDS)
August 15, 1994... X International Conference on AIDS Barbers are becoming AIDS experts in India, according to a presentation to the X International Conference on AIDS in Yokohama, Japan, August 7-12, 1994. Jacob K. John, a psychiatrist in Vellore,...

Yokohama hosts AIDS conference, but doesn't have AIDS there. (X International Conference on AIDS)
August 15, 1994... X International Conference on AIDS Hospitals in Yokohama, Japan, "are not yet ready or reluctant to accept HIV/AIDS cases," according to a study presented to the X International Conference on AIDS, held in that city August 7-12, 1994. ...

Blood banks called greedy at AIDS conference. (X International Conference on AIDS)
August 15, 1994... X International Conference on AIDS Blood banks were not held in high esteem at a satellite symposium held on August 6, 1994, just before the opening of the X International Conference on AIDS in Yokohama, Japan. Bruce Lee Evatt,...

Hivid (zalcitabine) available as monotherapy for HIV infection. (X International Conference on AIDS)
August 15, 1994... X International Conference on AIDS The U.S. Food and Drug Administration (FDA) has granted Hoffmann-La Roche, Inc., Nutley, New Jersey, marketing authorization for use of HIVID (zalcitabine), also known as ddC, as a monotherapy treatment...

Impact of secondary prophylaxis against PCP on global survival and frequency of relapses in HIV+ subjects. (Research Report)
August 15, 1994... AUTHORS: A. Chiodera, S. Casari, A. Bergamasco, A. Donisi, M. Gulletta and G. Carosi. University of Brescia, Brescia, Italy. According to an abstract submitted by the authors to the Fourth European Conference on Clinical Aspects and...

Pneumocystis carinii pneumonia in a cohort of 111 men with haemophilia infected with HIV. (Research Report)
August 15, 1994... AUTHORS: C.A. Sabin, J. Elford, A.N. Phillips, G. Janossy and C.A. Lee. Royal Free Hospital, School of Medicine, London, United Kingdom. According to an abstract submitted by the authors to the Fourth European Conference on Clinical...

Zidovudine plus Thymostimulin: a controlled study on 200 subjects. (Research Report)
August 15, 1994... AUTHORS: G. Barbarini, A. Malfitano, B. Grisorio, P. Sacchi, G. Garavelli, A. Trasforini, R. Bruno and D. Capelli. University of Pavia, Pavia, Italy. According to an abstract submitted by the authors to the Fourth European Conference...

Effect of zinc supplementation on opportunistic infections in AIDS. (Research Report)
August 15, 1994... AUTHORS: E. Mocchegiani, S. Veccia, F. Ancarani, G. Scalise and N. Fabris. INRCA, Ancona, Italy; 'Umberto I' Hospital, Ancona, Italy. According to an abstract submitted by the authors to the Fourth European Conference on Clinical...

New pseudopeptide inhibitors of aspartic protease HIV-1. (Research Report)
August 15, 1994... AUTHORS: S. Miertus 1, N. Antcheva 2, A. Tossi 2, F. Bizik 1, F. Benedetti 3, R. Gennaro 1 and D. Romeo 1. 1International Institute for Chemistry, UNIDO, Trieste, Italy; 2University of Trieste, Trieste, Italy; and 3University of Udine, Udine,...

Development of a shotgun-type anti-HIV-1 multi-targeted ribozyme expression plasmid to achieve effective protection against HIV-1 infection. (Research Report)
August 15, 1994... AUTHORS: J. Ohkawa 1, N. Yuyama 1, M. Homann 4, G. Sczakiel 4, H. Sato 2, Y. Takebe 2 and K. Taira 1. 1National Institute of Bioscience and Human Technology, Ibaraki, Japan; 2National Institute of Health, Tokyo, Japan; 3Ibaraki University,...

Mechanisms of the inhibition of the interferon response in HIV-infected cells. (Research Report)
August 15, 1994... AUTHORS: C. Lallemand 1, P. Rizza 2, P. Lebon 3 and M.G. Tovey 1. 1C.N.R.S, Villejuif, France; 2Ist Superiore di Sanita, Rome, Italy; and 3Hopital Saint-Vincent de Paul, Paris, France. According to an abstract submitted by the authors to...

Amino acid substitutions in the human immunodeficiency virus type 1 gp120 V3 loop that change viral tropism also alter physical and functional properties of the virion envelope. (reprinted from Journal of Virology, July 1994)(Periodical Report) (Abstract)
August 15, 1994... SOURCE: Journal of Virology, July 1994;68(7):4409-4419. According to the authors' abstract of an article published in the Journal of Virology, "The third variable (V3) region within the gp120 envelope glycoprotein of the human...

Changes in the cytopathic effects of human immunodeficiency virus type 1 associated with a single amino acid alteration in the ectodomain of the gp41 transmembrane glycoprotein. (reprinted from Journal of Virology, July 1994)(Periodical Report) (Abstract)
August 15, 1994... SOURCE: Journal of Virology, July 1994;68(7):4662-4668. According to the authors' abstract of an article published in the Journal of Virology, "A human immunodeficiency virus type 1 mutant with a single amino acid change (designated...

Demented and nondemented patients with AIDS differ in brain-derived human immunodeficiency virus type 1 envelope sequences. (reprinted from Journal of Virology, July 1994)(Periodical Report) (Abstract)
August 15, 1994... SOURCE: Journal of Virology, July 1994;68(7):4643-4649. According to the authors' abstract of an article published in the Journal of Virology, "Human immunodeficiency virus (HIV) dementia is a common clinical syndrome of uncertain...

Human immunodeficiency virus type 1 tat upregulates interleukin-2 secretion in activated T cells. (reprinted from Journal of Virology, July 1994)(Periodical Report) (Abstract)
August 15, 1994... SOURCE: Journal of Virology, July 1994;68(7):4177-4185. According to the authors' abstract of an article published in the Journal of Virology, "Dysregulation of cytokines secreted by T cells may play an important role in the...

Human immunodeficiency virus type 1 variants with increased replicative capacity develop during the asymptomatic stage before disease progression. (reprinted from Journal of Virology, July 1994)(Periodical Report) (Abstract)
August 15, 1994... SOURCE: Journal of Virology, July 1994;68(7):4400-4408. According to the authors' abstract of an article published in the Journal of Virology, "We examined the replicative properties of a series of sequential isolates and biological...

Suppression of tissue levels of vitamin A, E, zinc and copper in murine AIDS. (reprinted from Nutrition Research, July 1994)(Periodical Report) (Abstract)
August 15, 1994... SOURCE: Nutrition Research, July 1994;14(7):1031-1041. According to the authors' abstract of an article published in Nutrition Research, "Female C57BL/6 mice were infected with LP-BM5 retrovirus, causing murine acquired immune...

Biological importance and cooperativity of HIV-1 regulatory gene splice accepters. (reprinted from Virology, July 1994)(Periodical Report) (Abstract)
August 15, 1994... SOURCE: Virology, July 1994;202(1):264-271. According to the authors' abstract of an article published in Virology, "The replication of HIV-1 mutants containing altered splice acceptor sequences was studied. The splice acceptor sites...

Functional significance of the dinucleotide bulge in stem-loop1 and stem-loop2 of HIV-2 TAR RNA. (reprinted from Virology, July 1994)(Periodical Report) (Abstract)
August 15, 1994... SOURCE: Virology, July 1994;202(1):202-211. According to the authors' abstract of an article published in Virology, "Human immunodeficiency virus types 1 and 2 (HIV-1 and HIV-2) encode related proteins called Tat-1 and Tat-2,...

HIV-2 EHO isolate has a divergent envelope gene and induces single cell killing by apoptosis. (reprinted from Virology, July 1994)(Periodical Report) (Abstract)
August 15, 1994... SOURCE: Virology, July 1994;202(1):471-476. According to the authors' abstract of an article published in Virology, "The human immunodeficiency virus type 2 (HIV-2)-related isolate, referred to as HIV-2 EHO, has been isolated from an...

Overview of X International Conference on AIDS. (August 7-12, 1994, Yokohama, Japan) (Editorial)
August 22, 1994... Editorial In this and subsequent issues, this newsletter continues its coverage of research findings from the X International Conference on AIDS, held August 7-12, 1994, in Yokohama, Japan. The following article by Daniel J. DeNoon,...

AIDS epidemic threatens Asia. (X International Conference on AIDS, August 1994, Yokohama, Japan)
August 22, 1994... Conference Coverage AIDS threatens to overwhelm many Asian nations, according to data presented by a Malaysian researcher at a plenary session of the X International Conference on AIDS, held August 7-12, 1994, in Yokohama, Japan. ...

Tuberculosis, HIV on collision course in Asia. (X International Conference on AIDS, August 1994, Yokohama, Japan)
August 22, 1994... HIV/TB Co-Epidemic The number of people in Asia who develop tuberculosis (TB) because they are infected with both HIV and the TB bacillus is expected to multiply nearly sevenfold this decade, according to the World Health Organization...