AIDS Weekly articles from April 2004

AIDS Weekly archives from April 2004

Cell-penetrating, Rev-binding peptides can protect against HIV.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- A novel class of cell-penetrating, Rev-binding peptides may protect against HIV infection. "New therapeutic agents able to block HIV-1 replication are eagerly sought after to increase the...

Fungal derivatives show promise as HIV integrase inhibitors.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- A series of fungal derivatives are highly active against a key HIV enzyme. "HIV-1 integrase is a critical enzyme for replication of HIV, and its inhibition is one of the most promising new drug...

Novel benzophenones show promise as anti-HIV NNRTIs.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Novel benzophenone non-nucleoside reverse transcriptase inhibitors (NNRTIs) are highly active against drug-resistant strains of HIV. In a recent study from Japan, the agents "GW4511, GW4751, and...

Hepatotoxic effects comparable for all ARVs.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- The drugs used to fight HIV infection all have comparable hepatotoxic effects. HIV patients "frequently present with elevated levels of serum transaminases (alanine aminotransferase [ALT] and/or...

Routine resistance testing can improve ART outcome in experienced patients.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Routine resistance testing can improve the outcome of ART in heavily-treated HIV patients. According to recent research from the United States, the "long-term efficacy of making resistance testing...

Vitamin A supplements may increase risk of vertical HIV transmission.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Vitamin A supplements may increase the risk of vertical HIV transmission. According to recent research from the United States, "[m]icronutrient status has been associated with shedding of human...

Ritonavir treatment may benefit glioblastoma patients.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Ritonavir therapy may be beneficial for glioma patients. "Glioblastoma is a therapeutic challenge as a highly infiltrative, proliferative, and resistant tumor," scientists in France explained....

Caelyx demonstrates efficacy, reduced cardiac toxicity.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Schering-Plough Europe reported that results of a randomized phase III clinical study demonstrated that Caelyx (pegylated liposomal doxorubicin hydrochloride) provided comparable efficacy in the...

Betulonic acid-based agents active against HIV, influenza A, other viruses.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- A group of betulonic acid-based agents have demonstrated activity against a variety of viruses, including HIV. In a study from Russia, "[b]etulonic acid amides with aliphatic and heterocyclic...

Biotechnology company completes $23.1M series B financing.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- VaxInnate Corporation has completed a $23.1 million, series B financing to advance the development of next-generation preventative vaccines and immune therapies for infectious disease and cancer. ...

Vaccine development helps drive company's 25% revenue increase in 2003.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- GenVec, Inc., (GNVC), announced financial results for the fourth quarter and year ended December 31, 2003. For the year ended December 31, 2003, GenVec reported a net loss of $21.3 million or $0.65...

Vestigial theta-defensin pseudogenes identified in humans.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- A group of vestigial theta-defensin pseudogenes have been identified in the human genome. According to recent research from the United States, "[r]etrocyclins (ancestral human theta-defensins) are...

Quebec calls 1200 people for HIV tests, acupuncture clinic reused needles.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- The Quebec government is asking 1200 people to undergo a blood test for HIV and hepatitis after needles were used more than once at a Montreal acupuncture clinic. Health officials told a news...

Canada's Foreign Minister says AIDS crisis has become a human rights issue.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- The worldwide AIDS epidemic is developing into an international human rights crisis, Foreign Affairs Minister Bill Graham said March 17, 2004. Graham, who was in Toronto for the official opening of...

Ohio AIDS center to close due to dwindling donations.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- An AIDS organization that helps patients and their families in northwest Ohio is closing after 15 years because of dwindling financial support. David's House Compassion will close April 1. "Our...

U.N. plan to treat HIV/AIDS sufferers endangered by lack of money.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- An ambitious plan to cut AIDS deaths in developing countries is in danger because governments have failed to come forward with funding for an important part of the operation, U.N. officials and...

Chemotherapy and HAART feasible for HIV-NHL patients.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Simultaneous chemotherapy and HAART regimens are feasible for HIV patients with non-Hodgkin lymphoma. Researchers in Italy "evaluated replication of human immunodeficiency virus (HIV) and the...

Soluble Fas levels in CSF correlate with HIV dementia severity.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Cerebrospinal fluid (CSF) sFas levels are correlated with the severity of HIV-associated dementia (HIV-D). "Soluble Fas (sFas) and soluble Fas ligand (sFasL) are associated with cellular...

MQoL-HIV provides accurate quality-of-life measure for Japanese HIV patients.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- The MQoL-HIV test is suitable for measuring quality of life in Japanese HIV patients. Scientists in Japan conducted a study "to evaluate the discriminative properties of the Multidimensional Quality...

AIDS awareness educators reach out to secretive gay Arab community.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- They may have arranged the Arabian Nights party, complete with loud Arabic dance music and flickering lights, but Chris Ayoub and David Ponsart came to the Ferndale bar mainly to spread a message of...

Changes in patterns of HIV infection in Italy characterized.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Changes in the epidemiology of HIV infection in Italy have been characterized. In a recent study, a group of researchers sought to characterize "the major changes in the human immunodeficiency...

First Mycobacterium haemophilum infection in AIDS patient in Italy reported.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- The first Mycobacterium haemophilum infection in an AIDS patient in Italy has been reported. M. haemophilum, "a strongly acid- and alcohol-fast bacillus belonging to the group of nontuberculous...

Novel Cryptococcus species isolated from AIDS patients.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- A novel Cryptococcus species has been identified. In a recent study from Japan, C. flavescens, "a strain originally identified as C. laurentii, was isolated from the cerebrospinal fluid of an AIDS...

AIDS prevention programs get $47 million infusion from Gates Foundation.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- The Bill and Melinda Gates Foundation on March 15, 2004, donated $47 million to private agencies carrying out AIDS prevention programs in India, a senior foundation official said. The money will...

Membrane-active gp41 regions identified.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Membrane-active regions of HIV gp41 have been identified using a novel technique. According to published research from Spain, the "identification of membrane-active regions of the ectodomain of the...

Cognitive account best explains "unrealistic optimism" about risky gay sex.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- The cognitive account best explains the thought processes of gay men who engage in high-risk sex. "Among the self-justifications that gay men use when deciding to have unprotected intercourse is...

Impact of HCV coinfection on risk of HAART-induced liver damage reviewed.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- The impact of HCV infection on the risk of HAART-induced liver damage has been reviewed. "Drug-induced liver injury (DILI) is the elevation of liver enzyme and/or bilirubin levels caused by the use...

Mitochondrial-to-nuclear DNA ratio may mark mitochondrial toxicity.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- The ratio of mitochondrial DNA to nuclear DNA may mark mitochondrial toxicity in nucleoside-treated HIV patients. "Nucleoside analogues inhibit human DNA polymerase gamma. As a result, they can...

NIH grant to fund drug development for multidrug-resistant HIV.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Chimerix, Inc., a biotechnology company developing orally available, targeted medicines for the treatment of smallpox, multidrug-resistant HIV and hepatitis virus infections, has been awarded a Phase I...

Untimed drug levels powerful tool for measuring treatment compliance.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Untimed drug levels are a powerful tool for measuring compliance with anti-HIV treatment. In a recent study, scientists in the United States "examined cross-sectionally the relationship between...

High-mannose-type oligosaccharides bind to human antibody 2G12.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- High-mannose-type oligosaccharides bind to human antibody 2G12, which has implications for HIV-1 vaccine design. According to a study from the United States, "Human antibody 2G12 broadly...

HIV p24 antigen test can detect subtype G strains.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- The p24 antigen HIV test can detect subtype G strains. "The expense of PCR testing limits diagnosis of HIV infection in infancy in low resource settings," scientists in South Africa explained. ...

Antiretroviral therapy does not prevent HPV-induced genital lesions.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Antiretroviral therapy does not protect HIV+ women against the effects of HPV infection. In a study from Italy, the "effect of antiretroviral therapy on the natural history of human papillomavirus...

IFN-alpha with ribavirin can suppress virus-specific immunity.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Treatment with interferon (IFN)-alpha and ribavirin may impair immune responses to non-HCV viruses. Anti-HCV treatment "combining IFN-alpha and ribavirin (IFN+R) has still poorly defined effects on...

Adaptive regulatory T cells suppress killing of persistently infected cells.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Scientists report that they have identified a cellular mechanism that prevents the immune system from destroying chronic, incurable viral infections such as herpes, hepatitis and human immunodeficiency...

Data presented on molecular mechanism of action for HE2000.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Hollis-Eden Pharmaceuticals, Inc., (HEPH) announced the presentation of additional data relating to the molecular mechanism of action by which its immune regulating hormone IMMUNITIN (HE2000) may...

Effects of morphine on HIV gp160-induced monocyte apoptosis clarified.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- The effects of morphine on HIV gp160-induced monocyte apoptosis have been clarified. In a recent study, neuroimmunologists in New York examined "the effect of HIV-l gp160 protein and morphine on...

Similarities between HIV infection and aging may aid fight against both.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Immunological similarities between HIV infection and aging may point to strategies for ameliorating both conditions. "Aging and HIV disease show certain immunological similarities," scientists in...

Rhode Island doctor found guilty of diluting vaccines.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- A Cranston, Rhode Island, doctor has been found guilty of product tampering and altering drugs for diluting vaccines he administered to his immigrant patients. A United States federal jury on March...

Doctors call for balancing of patient/worker viral transmission protection.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Health care staff are at a much higher risk of acquiring viral infections from infected patients than vice versa. These viral infections include HIV and hepatitis. Despite this, patients receive...

Bosko Djordjevic elected to board of directors.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Lipid Sciences, Inc., (LIPD) announced that Bosko Djordjevic was elected to the board of directors on March 2, 2004. Lipid Sciences is a development-stage biotechnology company engaged in the...

Controversial polio vaccines are safe, Nigerian president says.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Independent tests on controversial polio vaccines used in Nigeria show they are safe, Nigeria's president said March 17, 2004, in a bid to ease Muslim fears the vaccines are contaminated with HIV and...

Returning to work is difficult for men with HIV/AIDS.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Men with HIV/AIDS may have a hard time returning to work after a period of unemployment, even if their health is improving, a new study said. A variety of barriers keep these men from re-entering...

Hispanics face significant disparities in pharmaceutical treatment.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Hispanics are less likely to receive or use medications for asthma, cardiovascular disease, HIV/AIDS, mental illness, and pain, according to a new study. These disparities in pharmaceutical...

Company announces an upgrade to ISO 9001:2000 certification.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- MedMira, Inc., (MIR) has received an upgrade to ISO 9001:2000 certification and has successfully completed its annual ISO 13485 audit. These certifications identify MedMira as having attained the...

Study confirms transmission of retrovirus.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- African ape hunters are being infected by the same class of viruses that causes AIDS, scientists say, raising fears of a possible epidemic of a new disease in the future. The finding was the first...

JUVEN added to Ross Products' line.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Abbott Laboratories' (ABT) Ross Products division has added JUVEN to its line of nutritional products. Based on blend of three key ingredients - arginine, glutamine, and...

New TB vaccine now in Phase I tests.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- A genetically engineered vaccine aimed at preventing tuberculosis was administered to volunteers at St. Louis University, part of a clinical trial that is the first-ever human testing of the vaccine...

Rifamycin resistance risk similar for rifampin and rifabutin DOT regimens.
April 5, 2004... 2004 APR 5 - (NewsRx.com & NewsRx.net) -- Rifampin- and rifabutin-based regimens carry comparable risks of inducing TB drug resistance. In a recent study, scientists in Tennessee "sought to determine the risk of acquired...

Novel HIV fusion inhibitor T-1249 safe, effective in early trials.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- The novel HIV fusion inhibitor T-1249 has proved to be safe and effective in early human trials. According to recent research from North Carolina, "T-1249 is a 39-aa synthetic peptide that...

HIV-infected cells have heightened vulnerability to electrical damage.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- HIV-infected cells are more susceptible to electrical damage than uninfected cells, a feature that could be exploited for novel anti-HIV therapies. "Use of combination anti-retroviral drug regimens...

Bone mineral loss frequent in female patients during HAART.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- The metabolic disruption associated with antiretroviral therapy often manifests as bone mineral density (BMD) loss in female HIV patients. Reduced BMD and "abnormalities in fat redistribution,...

Murine spatial learning and long-term potentiation disrupted by HIV Tat.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- The HIV Tat protein disrupts neurological activity related to spatial learning in mice. "Although memory deficits have been clearly documented in patients with human immunodeficiency virus type-1...

Thiol/disulfide exchange needed for R4 HIV T-cell fusion during viral entry.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- Thiol/disulfide exchange is needed for envelope-mediated T-cell fusion by R4 HIV strains. "Attachment of gp120 to CD4 during HIV-1 entry triggers structural rearrangement in gp120 that enables...

Novel immunoassay distinguishes KS from mimics.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- A novel immunoassay reliably distinguishes between human herpesvirus 8 (HHV-8)-induced Kaposi sarcoma and similar conditions. HHV-8 "is recognized as a major causal agent of Kaposi sarcoma (KS),...

Heart disease more common, progresses quicker in HIV patients.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- Now that treatments have been successful at helping HIV patients live longer, these patients are facing a new health challenge - high rates of rapidly progressive atherosclerosis, researchers report....

Immtech continued to prepare for commercialization.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- Immtech International, Inc., (IMM) has signed an agreement with Cambrex Charles City, Inc., a subsidiary of Cambrex Corp. (CBM), a provider to the pharmaceutical industry, to develop an enhanced...

Project aims to develop microbicides to protect women against HIV.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- While condom use remains the most effective protection against sexual transmission of HIV, it is clear that in many parts of the world women are not empowered to insist on it. The urgent need for...

Biotech company loss of $0.05 per share, provides clinical update.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- Enzo Biochem, Inc., (ENZ) reported operating results for the second fiscal quarter ended January 31, 2004, and improved sequential performance at Enzo Life Sciences. Reflecting principally the...

Biotech company reports 2003 net loss of $11.0 million.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- Lipid Sciences, Inc., (LIPD) reported results for the fourth quarter and the year ended December 31, 2003. Lipid Sciences is a development-stage biotechnology company engaged in the research and...

AIDS conference to mobilize leaders to get drugs to the needy.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- This year's International AIDS Conference will attempt to mobilize political will to effectively distribute new medicines to combat the deadly disease, a conference organizer said March 22, 2004. ...

African delegates meet to plan joint response to AIDS pandemic.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- Representatives from four HIV-plagued African countries gathered in Maputo, Mozambique, on March 23, 2004, to discuss a common strategy against the pandemic that is ravaging the continent. "The...

Applications submitted for fixed-dose coformulation of Viread and Emtriva.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- Gilead Sciences, Inc., (GILD) announced the submission of a new drug application to the U.S. Food and Drug Administration (FDA) for marketing approval of a fixed-dose coformulation of the company's...

Health Canada official to join global HIV partnership.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- The International Partnership for Microbicides (IPM) announced the appointment of a government official to advance a public-private health partnership. Under the terms of the agreement, Martin...

More government, community involvement needed to tackle Asia AIDS epidemic.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- International AIDS experts urged Asian governments and communities on March 24, 2004, to step up efforts to stop the deadly disease from spreading in the region. "We don't need just doctors. We...

Phase I clinical trial initiated for PA-457 oral anti-HIV compound.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- Panacos Pharmaceuticals, Inc., has begun a phase I clinical trial of its small molecule HIV drug candidate PA-457. PA-457 has a different mechanism of action than approved HIV drugs and has potent...

Retina Rainbow HIV-1 RNA test distributors announced.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- Primagen Holding B.V. has entered into distribution agreements for its Retina Rainbow products with Farmaplus N.V., having its offices in Curacao, Netherlands Antilles; Ilex Pty LTD, having its main...

U.N. report: AIDS threatens China's progress in living standards.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- Environmental damage, rising HIV infection rates and growing urban poverty are threatening improvements in China's living standards, the United Nations said in a report released March 25, 2004. ...

Media coverage of HIV/AIDS decreasing, but focus on global epidemic increasing.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- Are the media experiencing "AIDS fatigue"? A new Kaiser Family Foundation study examining 22 years of news coverage finds that overall media coverage is decreasing, while the amount of coverage of the...

Anti-HHV-8 therapy effective against multicentric Castleman disease.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- Anti-HHV-8 therapy is beneficial for multicentric Castleman disease patients. MCD is "a lymphoproliferative disorder associated with human herpesvirus 8 (HHV-8) infection among persons with human...

Bone marrow features in AIDS patients characterized.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- The clinical features of bone marrow in contemporary and historical AIDS cohorts have been characterized. In a recent study, scientists in the United States "compared bone marrow findings in two...

Development of indinavir resistance can be insidious.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- The develoment of indinavir resistance by HIV can be an insidious process. In a recent study, scientists in the United States "evaluated zidovudine-experienced patients for whom treatment with...

"Dipping" may throw off conventional measures of sexual behavior.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- The practice of "dipping" may throw off conventional measures of male-male sexual behavior. According to scientists in the United States, "[b]rief acts of unprotected anal sex (i.e. 'dipping')...

HIV rates rising among the elderly.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- Happily involved in a relationship with a flirtatious, handsome man, Alice Renwick gave little thought to the possibility of contracting HIV. At 65, Renwick, an infection control nurse at a...

HIV subtype trends in Uganda determined.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- The trends in HIV subtype prevalence in Uganda have been evaluated. Scientists in Uganda conducted a study to identify "changes in the subtypes of HIV-1 infecting a rural Ugandan cohort where the...

Pacific islands face rapidly expanding HIV epidemic.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- The Pacific Island countries have a unique opportunity to curb the spread of HIV/AIDS before it is too late. "Although HIV prevalence levels remain low, we must not underestimate the size of the...

Effect of within-patient HIV mutation on population-level evolution clarified.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- The effects of HIV mutations within patients on population-level viral evolution have been elucidated. "Within-patient HIV evolution reflects the strong selection pressure driving viral escape...

Recombination dynamics of HIV genome determined.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- The dynamics of HIV genome recombination have been characterized. "Recombination plays a pivotal role in the evolutionary process of many different virus species, including retroviruses,"...

HIV-induced phenotype changes hamstring Gag-specific CD4 cells.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- CD4 cells specific for the HIV Gag protein undergo virus-induced phenotypical changes that reduce their efficacy. According to recent research from the United States, an "in vitro proliferative...

HIV-infected lymphocytes modulate fibronectin output via TGFbeta1 secretion.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- HIV-infected lymphocytes modulate fibronectin output through TGFbeta1 secretion. "Alterations in lymph node architecture occur with HIV infection and contribute to immunological derangements,"...

Interaction between Leishmania and HIV clarified.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- The pathological interactions between HIV andLeishmania have been clarified. "Parasitic infections such as leishmaniasis can modulate the life cycle of HIV-1 and disease progression," immunologists...

Effects of HAART on CNS disorders elucidated.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- The effect of antiretroviral therapy on CNS disease has been elucidated. According to neurologists in Italy, a "drastic decrease in incidence has been observed for most human immunodeficiency virus...

Failures of Russian AIDS policy dissected.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- The numerous failures of the Russian approach to HIV/AIDS management have been dissected. For a variety of reasons, "the Russian state has had limited success in tackling the growing problem of...

Politics of AIDS control in Uganda examined.
April 12, 2004... 2004 APR 12 - (NewsRx.com & NewsRx.net) -- The politics of AIDS control in Uganda have been characterized. In a recent study, researchers in England evaluated "the political dimensions of Uganda's progress in bringing a generalized...