AIDS Weekly articles from April 2001

AIDS Weekly archives from April 2001

Four-Drug Antiretroviral Regimen Effective For Amprenavir-Experienced Patients.(indinavir, nevirapine, stavudine, and lamivudine)
April 2, 2001... 2001 APR 2 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - An antiretroviral cocktail combining indinavir, nevirapine, stavudine, and lamivudine can provide substantial viral inhibition in amprenavir-experienced...

Monkeys Don't Develop AIDS Despite High Virus Levels.(simian immunodeficiency virus does not develop into AIDS)
April 2, 2001... 2001 APR 2 - (NewsRx.com & NewsRx.net) -- African green monkeys do not develop AIDS despite high levels of the simian immunodeficiency virus (SIV) in their blood. This surprising finding challenges some commonly held beliefs about how...

Postexposure Prophylaxis Feasible And Effective.(in HIV infection prevention)
April 2, 2001... 2001 APR 2 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Researchers in California say that postexposure prophylaxis (PEP) - treatment given to prevent HIV infection after possible exposure - can help prevent the...

Study Ties Depression, Anxiety To Fatigue In HIV Patients.
April 2, 2001... 2001 APR 2 - (NewsRx.com & NewsRx.net) -- One of the most difficult and frustrating problems for people who test positive for HIV is fatigue, but often doctors can't recommend much more to patients than getting additional rest....

Leukemia Inhibitory Factor Can Prevent Vertical Transmission.(between mother and child)
April 2, 2001... 2001 APR 2 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Researchers in Illinois have shown that leukemia inhibitory factor (LIF), produced by the placenta, is a powerful inhibitor of HIV replication and may play a...

Some Antiretroviral Drugs Can Improve Psychomotor Dysfunction in HIV Patients.
April 2, 2001... 2001 APR 2 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Psychomotor dysfunction caused by HIV infection can be reversed by some antiretroviral therapies, researchers in Germany say. "Since psychomotor slowing...

Interleukin-2 Can Hasten Immune Recovery In Patients Responding Slowly To ART.(antiretroviral therapy)
April 2, 2001... 2001 APR 2 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - The cytokine interleukin-2 can help prevent infectious morbidity in HIV patients who do not respond quickly to antiretroviral therapy, researchers in France...

Family Important Source Of Support For HIV Positive Men.
April 2, 2001... 2001 APR 2 - (NewsRx.com & NewsRx.net) -- People diagnosed with HIV often turn to friends for support, and that's encouraged by doctors and therapists. But Ohio State University research suggests this advice may not go far enough. ...

Despite T-Cell Decline, Antiretroviral Therapy Does Not Impair Immune Response.
April 2, 2001... 2001 APR 2 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Reduced levels of cytotoxic T lymphocytes (CTLs) caused by combination antiretroviral therapy apparently do not impair HIV specific CTL responses. ...

Free Database On Active HIV Inhibiting Compounds Offered.(by MDL Information Systems Inc.)
April 2, 2001... 2001 APR 2 - (NewsRx.com & NewsRx.net) -- MDL Information Systems, Inc., has released a free database containing information on selected compounds found to be active in the U.S. National Cancer Institute's AIDS antiviral screen. The...

KNI-272 Targets Two Viral Replication Stages.(in HIV viruses)
April 2, 2001... 2001 APR 2 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - The protease inhibitor KNI-272 blocks HIV replication at two distinct stages in the process, according to microbiologists in Japan. T. Goto and...

Soluble CD16 Can Block CR3-Mediated Infection.(HIV monocyte infection)
April 2, 2001... 2001 APR 2 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Soluble CD16 (sCD16), a ligand of the CR3 receptor, can block HIV monocyte infection by opsonized viruses, according to researchers in France. Hicham...

Study Links HAART To Decline In Hospital Costs For Most, But Not All HIV Patients.(highly active antiretroviral therapy)
April 2, 2001... 2001 APR 2 - (NewsRx.com & NewsRx.net) -- A U.S. study sponsored by the federal Agency for Healthcare Research and Quality (AHRQ) has found that expenditures for hospital inpatient care for HIV fell more than 40% by mid-1997 in the wake of...

Treatment for HIV Disease Found Cost-Effective.
April 2, 2001... 2001 APR 2 - (NewsRx.com & NewsRx.net) -- Three-drug combination therapy for HIV, despite its great expense, is a very cost-effective use of resources, report researchers from Massachusetts General Hospital (MGH) and their colleagues in the...

Interventions Should Take Into Account Gender Differences In Behavior.(gender-based health risk behavior)
April 2, 2001... 2001 APR 2 - (NewsRx.com & NewsRx.net) -- Researchers in Canada have determined sex-related differences in risk behavior could have implications for the development of preventive and clinical interventions. Injection drug use has been...

CDC Selects Rapid HIV Testing For Treatment Investigational Device Exemption.(OraQuick HIV-1/2 rapid HIV test)
April 2, 2001... 2001 APR 2 - (NewsRx.com & NewsRx.net) -- OraSure Technologies, Inc., announced that the U.S. Centers for Disease Control and Prevention (CDC) has selected the OraQuick HIV-1/2 rapid HIV test to be used in the CDC-sponsored Treatment...

Adrenal Insufficiency in HIV Patients Possible Despite Negative Test Results.
April 2, 2001... 2001 APR 2 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - HIV patients with symptoms of adrenal insufficiency may suffer from the disorder even if initial test results are negative, endocrinologists point out. ...

High Rates In Spain Necessitate HIV Resistance Testing.(drug resistance testing)
April 2, 2001... 2001 APR 2 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Relatively high levels of HIV drug resistance since the introduction of protease inhibitors in Spain make resistance testing a virtual necessity there. ...

Study Finds HIV Genotype Testing is Cost-Effective.
April 2, 2001... 2001 APR 2 - (NewsRx.com & NewsRx.net) -- Tests of HIV genes for signs of resistance to particular drugs can help identify drug-resistant mutations. This information could be used to guide the choice of drug therapy, especially after a...

Thailand: Epidemic Has Slowed, But AIDS-Related Opportunistic Infections Have Increased.
April 2, 2001... 2001 APR 2 - (NewsRx.com & NewsRx.net) -- Researchers at the Johns Hopkins School of Public Health have found that while Thailand has mounted an effective program for preventing the sexual transmission of the human immunodeficiency virus...

Reduced Sexual Exposure May Cause Infection In Resistant Prostitutes.(Brief Article)
April 2, 2001... 2001 APR 2 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Reduced workloads may result in late HIV infection for seemingly resistant prostitutes, researchers in England say. "Resistance to HIV infection in a...

Local Transmission Rates Determine If Vaccination Risks Outweigh Benefits.(Brief Article)
April 2, 2001... 2001 APR 2 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - Public health policy will have to take into account HIV transmission rates when addressing whether vaccination with live attenuated HIV is worth the risk....

New Study To Investigate Chemokine Inhibitor's Role In Increasing White Blood Cells.(Brief Article)
April 2, 2001... 2001 APR 2 - (NewsRx.com & NewsRx.net) -- AnorMED announced March 19, 2001, that it has initiated a new Phase I clinical trial in healthy volunteers to study the white blood cell count increasing effects of AMD-3100, an inhibitor of the...

Talking Device Keeps HIV Patients On The Straight And Narrow.(Brief Article)
April 2, 2001... 2001 APR 2 - (NewsRx.com & NewsRx.net) -- Sometimes the simplest things can make a dramatic difference in medicine. Johns Hopkins researchers report that a portable device that's "a cross between a pager and your own mother" can,...

Psychostimulants Can Reduce Fatigue.(Brief Article)
April 2, 2001... 2001 APR 2 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Fatigue related to HIV infection can be successfully treated with psychostimulants like Ritalin, researchers in China say. "Fatigue is a commonly...

Novel Compound Inhibits HIV Replication In Cell Cultures.(Brief Article)
April 9, 2001... 2001 APR 9 - (NewsRx.com & NewsRx.net) -- A compound that inhibits human immunodeficiency virus (HIV) in human immune system cells may eventually provide a new therapeutic approach against the virus by blocking infection at an early stage....

CD4-Independent Mutants More Susceptible To Neutralization.(Brief Article)
April 9, 2001... 2001 APR 9 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - HIV variants that do not need the presence of CD4 for cell entry are less resistant to immune activity than the normal virus, which may account the rarity of...

Antibody 17b May Hold Key To Blocking Viral Entry.(Brief Article)
April 9, 2001... 2001 APR 9 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - The mechanisms by which the HIV antibody 17b interferes with viral cell entry may aid in the creation of new HIV inhibitors, say researchers in Pennsylvania....

International OPTIMA Study Will Target Patients For Whom HAART Has Failed.(Brief Article)
April 9, 2001... 2001 APR 9 - (NewsRx.com & NewsRx.net) -- Researchers from the United States, Canada, and the United Kingdom are collaborating to evaluate the best treatment strategies for HIV infected patients for whom highly active antiretroviral therapy...

Lipodystrophy Risk Factors During Protease Inhibitor Therapy Hard To Pinpoint.(Brief Article)
April 9, 2001... 2001 APR 9 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Researchers in Spain report that a wide variety of clinical variables can affect the risk of HIV wasting syndrome, or lipodystrophy, during highly active...

Regulatory Proteins Can Disrupt DNA Repair.(Brief Article)
April 9, 2001... 2001 APR 9 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - During HIV related lymphomas, the HIV regulatory protein Tat apparently alters the expression of the DNA polymerase (beta) ((beta)-pol) gene. Deepak K....

Soluble Immune Markers May Provide Low-Cost Screening Alternative For Poor Countries.(Brief Article)
April 9, 2001... 2001 APR 9 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - HIV progression tests that measure plasma levels of immune markers may provide a cost-effective alternative for areas without access to more advanced...

Tat Protein Induces Complex Changes In Interleukin-2 Transcription.(Brief Article)
April 9, 2001... 2001 APR 9 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - The HIV Tat protein engages in complex fine-tuning of transcription factor activity in order to prevent interleukin-2 (IL-2) production, researchers in Spain...

Ethiopian Medicinal Plant Extracts Show Promise For Treatment.(Brief Article)
April 9, 2001... 2001 APR 9 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Several substances derived from traditional Ethiopian medicinal plants may be effective antiviral compounds, according to researchers writing in the journal...

HIV Patients Report Fewer Gastrointestinal Side Effects With Videx Capsules.(Brief Article)
April 9, 2001... 2001 APR 9 - (NewsRx.com & NewsRx.net) -- Study results indicate switching from Videx(R) (didanosine) chewable tablets to Videx EC(R) capsules, (enteric coated beadlets of idanosine) may significantly reduce common gastrointestinal (GI)...

Preliminary Data Reported From Phase II Clinical Study of VX-175.(Brief Article)
April 9, 2001... 2001 APR 9 - (NewsRx.com & NewsRx.net) -- Preliminary results from a 28-day Phase II clinical study of VX-175, a prodrug of the HIV protease inhibitor amprenavir, were presented at the 8th Conference on Retroviruses and Opportunistic...

Transmucosal Drug To Begin Trials In South Africa.(Brief Article)
April 9, 2001... 2001 APR 9 - (NewsRx.com & NewsRx.net) -- Hollis-Eden Pharmaceuticals, Inc. (HEPH) March 21, 2001, announced it has received clearance from the South African Medicines Control Council (MCC) to initiate testing of a new transmucosal (buccal)...

Opioids Can Worsen Tat-Induced Damage.(Brief Article)
April 9, 2001... 2001 APR 9 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Opioid treatment can exacerbate neurologic damage caused by the HIV Tat protein, warn researchers writing in the journal Neuroscience. "[HIV] infection...

Reduced CREB Expression May Underlie Neurotoxicity.(Brief Article)
April 9, 2001... 2001 APR 9 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Neurologic damage caused by the HIV Tat protein may be mediated by reduced expression of the neuroprotective protein CREB, researchers in Italy suggest. ...

Needle-Free Device To Deliver Human Growth Hormone Receives U.S. Market Clearance.(Brief Article)
April 9, 2001... 2001 APR 9 - (NewsRx.com & NewsRx.net) -- The U.S. Food and Drug Administration (FDA) has granted market clearance for a needle-free device to deliver Serostim (somatropin (rDNA origin) for injection), Serono's recombinant human growth...

Phenotypic Analysis May Identify Which Patients Will Respond To Antiretroviral Therapy.(Brief Article)
April 9, 2001... 2001 APR 9 - (NewsRx.com & NewsRx.net) -- Fourteen new research presentations using ViroLogic Inc.'s (VLGC) PhenoSense(TM) HIV technology were presented at the 8th Conference on Retroviruses and Opportunistic Infections. The studies...

South African Government Says One In Nine Is Now HIV Positive.(Brief Article)
April 9, 2001... 2001 APR 9 - (NewsRx.com & NewsRx.net) -- One in nine South Africans is infected with HIV, the government said March 20, 2001. The number of cases is growing in the country that already had the world's largest population of HIV...

Collaboration Aims To Advance Prophylactic Immunization In Developing Countries.(Brief Article)
April 9, 2001... 2001 APR 9 - (NewsRx.com & NewsRx.net) -- In continuing efforts to curb the global spread of AIDS, The International AIDS Vaccine Initiative (IAVI) and Therion Biologics will collaborate as new partners to develop prophylactic AIDS vaccines...

Positive Pre-Clinical Data Reported On Vaccine Designed To Combat HIV's Ability To Mutate.(Brief Article)
April 9, 2001... 2001 APR 9 - (NewsRx.com & NewsRx.net) -- Epimmune Inc. (EPMN) announced on April 2, 2001, positive pre-clinical data on its HIV vaccine that is designed to directly address the problem of viral mutation. At the Keystone Symposium...

Second IAVI-Sponsored Vaccine For Africa Enters Human Trials In U.K.(Brief Article)
April 9, 2001... 2001 APR 9 - (NewsRx.com & NewsRx.net) -- The second International AIDS Vaccine Initiative (IAVI-) sponsored preventive HIV vaccine designed specifically for Africa entered human trials on March 14, 2001, in the U.K. with the inoculation of...

Filgrastim Effective As Part Of Oral Regimen For AIDS Patients.(Brief Article)
April 9, 2001... 2001 APR 9 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - The addition of oral filgrastim to chemotherapy for non-Hodgkin's lymphoma can improve the quality and duration of life for afflicted AIDS patients, study...

Criteria Set For Defining Physician Specialists In HIV/AIDS.(Brief Article)
April 9, 2001... 2001 APR 9 - (NewsRx.com & NewsRx.net) -- The American Academy of HIV Medicine (AAHIVM) has established criteria defining what it means to be a specialist among physicians and other health care workers treating individuals with HIV/AIDS....

Efavirenz-Based Therapy More Cost-Effective Than Indinavir Regimens.(Brief Article)
April 9, 2001... 2001 APR 9 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Antiretroviral treatment regimens containing efavirenz are markedly more cost-effective than similar therapies based on indinavir, according to researchers...

Splenic Irradiation Is An Option For Patients With Autoimmune Disorders And Those With HIV.(Brief Article)
April 9, 2001... 2001 APR 9 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Splenic irradiation can be used as an alternative treatment for patients with autoimmune blood disorders and patients infected with HIV, researchers in...

Collaboration Aims To Elicit Broader, Stronger Immune Response Against HIV.(Brief Article)
April 9, 2001... 2001 APR 9 - (NewsRx.com & NewsRx.net) -- Maxygen Inc. (MAXY), the International AIDS Vaccine Initiative (IAVI), and DBLV LLC, an entity established and funded by the Rockefeller Foundation, announced the formation of a three-year...

Antiretroviral Drugs Can Alter Predominant Viral Strains.(Brief Article)
April 16, 2001... 2001 APR 16 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Antiretroviral therapy changes the predominant viral phenotype in HIV patients by repressing the more virulent strain found in end-stage disease,...

Antiretroviral Therapy Reduces Need For Prophylactic Treatment.(Brief Article)
April 16, 2001... 2001 APR 16 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - The advent of potent antiretroviral therapy for HIV infection has reduced - and possibly eliminated - the need for opportunistic infection prophylaxis,...

Abacavir Equivalent To Indinavir For Patients With Moderate Viral Loads.(Brief Article)
April 16, 2001... 2001 APR 16 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - For patients with low or moderate HIV loads, the nucleoside analog abacavir is as effective as the protease inhibitor indinavir as part of an antiretroviral...

Women Account For Increasing Share Of New Infections.(Brief Article)
April 16, 2001... 2001 APR 16 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - HIV infection is become increasingly common among women in the United States, even among what have been considered low-risk populations, government...

Methinone Enkephalin Increases Immune Cell Count.(Brief Article)
April 16, 2001... 2001 APR 16 - (NewsRx.com & NewsRx.net) -- Researchers with Vector Medical Technologies, Inc., reported study results demonstrating the company's Methinone enkephalin vaccine increases numbers of T cells and natural killer cells in HIV...

Preclinical Data Indicate Candidate Vaccine's Ability To Inhibit Viral Mutation.(Brief Article)
April 16, 2001... 2001 APR 16 - (NewsRx.com & NewsRx.net) -- Epimmune, Inc. (EPMN) announced on April 2, 2001, positive pre-clinical data on its HIV vaccine, which is designed to directly address the problem of viral mutation. Company scientists...

Infection Linked To Drug Use In Women.(Brief Article)
April 16, 2001... 2001 APR 16 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Intravenous drug use and sexually transmitted diseases in women are linked to infection with human herpesvirus-8, the virus responsible for Kaposi's...

Dental Problems Go Unresolved In Many HIV Patients.(Brief Article)
April 16, 2001... 2001 APR 16 - (NewsRx.com & NewsRx.net) -- Oral infections, mouth ulcers, and other severe dental conditions associated with HIV infections go untreated more than twice as often as other health problems related to the disease, according to...

Antiretroviral Treatment Improves Neurocognitive Function In Women.(Brief Article)
April 16, 2001... 2001 APR 16 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Highly active antiretroviral therapy (HAART) can prevent HIV related cognitive impairment in women, suggest new study results. R.A. Cohen and...

Combination Antiretroviral Tablet Does Not Alter Pharmacokinetics.(Brief Article)
April 16, 2001... 2001 APR 16 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - A single tablet combining doses of abacavir, lamivudine, and zidovudine is equivalent to individual doses of these antiretroviral drugs, according to...

Coordinated Response Still Lacking To Ensure Accessible Drugs To Sub-Saharan Africa.(Brief Article)
April 16, 2001... 2001 APR 16 - (NewsRx.com & NewsRx.net) -- The following report was issued by the UN Integrated Regional Information Network (IRIN). It does not necessarily reflect the views of the United Nations, the Network said. [helv] One of the...

Cuba Poised To Enter Generic Drug Market.(Brief Article)
April 16, 2001... 2001 APR 16 - (NewsRx.com & NewsRx.net) -- South African president Thabo Mbeki signed a series of agreements in Havana the week of April 2, 2001, with his Cuban counterpart Fidel Castro, one of which could clear the way for the two...

Efavirenz Beats Cocktail In Three-Year Viral Suppression.(Brief Article)
April 16, 2001... 2001 APR 16 - (NewsRx.com & NewsRx.net) -- Data presented April 2, 2001, at the 11th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) meeting indicate that DuPont Pharmaceuticals' anti-HIV drug Sustiva(TM)...

Investigational Drugs In Combination Enhance Antiviral Activity.(Brief Article)
April 16, 2001... 2001 APR 16 - (NewsRx.com & NewsRx.net) -- Progenics Pharmaceuticals, Inc. (PGNX) announced on April 5, 2001, the publication of a scientific article showing that the investigational drugs PRO 542 and T-20 significantly enhanced anti-HIV...

Protease Inhibitors Not Linked To Premature Atherosclerosis.(Brief Article)
April 16, 2001... 2001 APR 16 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Although protease inhibitors used to treat HIV infection have been linked to lipid disorders, AIDS researchers in Switzerland say that their use does not...

Thiazolyl Thiourea Compounds Show Therapeutic Promise.(Brief Article)
April 16, 2001... 2001 APR 16 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - A number of thiazolyl thiourea derivatives possess potent and selective HIV inhibitory ability. pharmaceutical researchers report. F.M. Uckun and...

Oral Valganciclovir Is Expected To Replace Ganciclovir IV.(Brief Article)
April 16, 2001... 2001 APR 16 - (NewsRx.com & NewsRx.net) -- Hoffmann-La Roche announced March 30, 2001, that the U.S. Food and Drug administration (FDA) has approved Valcyte(TM) (valganciclovir) for the treatment of cytomegalovirus (CMV) retinitis in AIDS...

Stigma, Poor Health Infrastructure Blamed For Increasing HIV/AIDS Cases In Nigeria.(Brief Article)
April 16, 2001... 2001 APR 16 - (NewsRx.com & NewsRx.net) -- At least one health specialist in Nigeria predicts the HIV/AIDS epidemic there will continue to grow. Speaking at a workshop on HIV/AIDS in Senegal, Prof. John Idoko from the department of...

Matrix Metalloproteinase Inhibitors Prevent Tat-Induced Neurotoxicity.(Brief Article)
April 16, 2001... 2001 APR 16 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Drugs that inhibit the activity of some cell-destroying enzymes can also block HIV related neuronal damage, researchers in Canada report. J.B. Johnston...

Kaposi's Sarcoma-Associated Virus Causes No Negative Health Effects In HIV(-).(Brief Article)
April 16, 2001... 2001 APR 16 - (NewsRx.com & NewsRx.net) -- New research at the University of Pittsburgh, Pennsylvania, shows that human herpesvirus 8, which often leads to Kaposi's sarcoma in HIV positive individuals, has no negative effect on healthy...

Low Calprotectin Levels May Raise Oral Candidiasis Susceptibility.(Brief Article)
April 16, 2001... 2001 APR 16 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Reduced calprotectin levels as a result of HIV infection may be a factor in the development of associated oral candidiasis. S.P. Sweet and colleagues...

Elevated Cytokine Levels Do Not Protect HIV Patients.(Brief Article)
April 16, 2001... 2001 APR 16 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Increased levels of pro-inflammatory cytokines do not affect the course of pleural tuberculosis in HIV infected patients, according to researchers in...

Controversial Ad Campaign Boosts Condom Sales In Nigeria.(Brief Article)
April 16, 2001... 2001 APR 16 - (NewsRx.com & NewsRx.net) -- Although the Society for Family Health (SFH) says it can't figure it out, undoubtedly the Society's explicit radio jingles account for at least part of the 30% increase in condom sales during the...

Gates Foundation Awards $10 Million To Develop New TB Diagnostics.(Brief Article)
April 16, 2001... 2001 APR 16 - (NewsRx.com & NewsRx.net) -- On the eve of World TB Day - March 24, 2001 - the Bill & Melinda Gates Foundation awarded US$10 million to the UNDP/World Bank/WHO Special Program for Research and Development in Tropical Diseases...

WHO: Access To TB Cure A Human Rights Imperative.(Brief Article)
April 16, 2001... 2001 APR 16 - (NewsRx.com & NewsRx.net) -- Joint efforts are needed to confront tuberculosis (TB) and HIV, according to Dr. Gro Harlem Brundtland, director-general of the World Health Organization. TB is a leading killer of people...

Individual Adjustments Help Determine Optimal Pediatric Indinavir Dosing.
April 23, 2001... 2001 APR 23 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Researchers in The Netherlands say that appropriate pediatric doses of the protease inhibitor indinavir are best determined on an individual basis. ...

Rabies Virus Vectors Induce T-Cell Response.
April 23, 2001... 2001 APR 23 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - HIV vectors based on the rabies virus induce robust T-cell responses, suggesting that such vectors may be useful in developing an HIV vaccine, researchers...

Gender Differences In HIV Viral Load May Affect Treatment.
April 23, 2001... 2001 APR 23 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - Guidelines for using antiretroviral HIV therapies may exclude many women from needed treatment because of gender-based viral load discrepancies, researchers...

African HIV-1 Epidemic Not Caused By More Infectious Viral Subtype.
April 23, 2001... 2001 APR 23 - (NewsRx.com & NewsRx.net) -- The explosive HIV-1 epidemic in sub-Saharan Africa is unlikely to be the result of a viral subtype with increased infectivity, according to the results of a study published in the April 14, 2001,...

HIV Nef Protein Plays Both Offense And Defense In Battle Between HIV And Body's Immune System.
April 23, 2001... 2001 APR 23 - (NewsRx.com & NewsRx.net) -- In fighting the body's immune system, HIV owes part of its success to its ability to destroy those cells normally recruited to mount the body's counter-attack against the HIV infected cells. Lying...

Clinical Trials Appropriate For High-Risk Cohorts In U.S.
April 23, 2001... 2001 APR 23 - (NewsRx.com & NewsRx.net) -- by N.R. Saltmarsh, staff medical writer - A prospective study of human immunodeficiency virus type 1 (HIV-1) incidence among high-risk cohorts lends support to the idea that HIV-1 vaccine trials...

Drug Manufacturers Agree To Speed Up Discounts For Drugs.
April 23, 2001... 2001 APR 23 - (NewsRx.com & NewsRx.net) -- At an unannounced meeting with U.N. Secretary-General Kofi Annan, the chief executives of six major drug companies agreed to speed up the reduction of prices of AIDS drugs to help control the AIDS...

Three-Month CD4 Counts Predict Long-Term Antiretroviral Outcome.
April 23, 2001... 2001 APR 23 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - CD4 cell levels after three months of highly active antiretroviral therapy (HAART) are highly indicative of the long-term outcome of such treatment,...

Tumor Necrosis Factor Binding Protein Ineffective For Stem Cell Recovery.
April 23, 2001... 2001 APR 23 - (NewsRx.com & NewsRx.net) -- by Michael Greer, staff medical writer - A soluble tumor necrosis factor (TNF) receptor does not produce significant hematopoietic recovery in HIV patients, despite promising results from in vitro...