AIDS Weekly articles from April 1992

AIDS Weekly archives from April 1992

Advisory committee recommends approval of DDC with AZT. (dideoxycytidine, zidovudine) (U.S. Food and Drug Administration's Antiviral Drugs Advisory Committee)
April 27, 1992... U.S. FDA A U.S. government panel recommended April 21, 1992, that the U.S. Food and Drug Administration (FDA) approve a new anti-AIDS drug, dideoxycytidine (ddC). The Antiviral Drugs Advisory Committee accepted the use of ddC when...

Passive Hyperimmune Therapy (PHT) awarded orphan drug status. (Medicorp Inc.)
April 27, 1992... Medicorp Inc. Medicorp Inc. announced that its sublicensee, HemaCare Corporation of Sherman Oaks, California, reported interim, 6-month results from its double-blind, placebo-controlled, clinical trials of Passive Hyperimmune Therapy...

Company is awarded patent covering GLQ223. (anti-AIDS drug alpha-trichosanthin) (Genelabs Technologies Inc.)
April 27, 1992... Genelabs Technologies Inc. Genelabs Technologies Inc., Redwood City, California, announced that it has been awarded a U.S. patent associated with the development of its anti-AIDS drug, GLQ223 (alpha-trichosanthin). The patent...

New cancer drug to be tested in AIDS-KS patients. (Kaposi's sarcoma; recombinant platelet factor 4) (Repligen)
April 27, 1992... Repligen The first subjects in clinical trials of a new antitumor agent will be patients with AIDS-associated Kaposi's sarcoma (KS), the journal Bio/Technology reports. Repligen Corporation, Cambridge, Massachusetts, has dedicated...

Credibility of U.S. AIDS test patent "damaged." (news leaks on Robert Gallo investigation) (U.S. National Institutes of Health)
April 27, 1992... U.S. NIH Doubts about the validity of the U.S. claim to a share of the HIV blood test apparently reach as high as U.S. National Institutes of Health (NIH) director Bernadine Healy, Science magazine reports. The 1987 patent...

Group presses Cal-OSHA for TB standards at hearing. (California Occupational Safety and Health Administration) (California State Employees Association)
April 27, 1992... California Concerned by an outbreak of TB in the state prison system, representatives of the California State Employees Association (CSEA) told a Cal-OSHA hearing in Sacramento, California, that tough new standards to protect workers...

Over 100,000 people infected with HIV. (Mexico)
April 27, 1992... Mexico More than 100,000 people in Mexico have been infected with HIV over the past 11 years, according to the Mexican health ministry's Department of Epidemiology. Health officials said that since the discovery of Mexico's first AIDS...

Population changes as AIDS epidemic progresses. (Tanzania)
April 27, 1992... Tanzania The rapid spread of AIDS in the African country of Tanzania will have far-reaching implications on the country's economy, according to a study done there by the government and two U.N. specialized agencies. The World...

Safe sex promotions questioned. (India)
April 27, 1992... India Indian health authorities promoting safe sex to stem a threatened AIDS epidemic are installing condom vending machines at railway and bus stations. Critics dismiss it as a gimmick, since most Indians have never even seen a...

Theatrical entertainment used as educational tool for AIDS awareness. (Thailand)
April 27, 1992... Thailand In the eastern province of SiSaket, one of the poorest regions in Thailand, the Adventist Development and Relief Agency (ADRA) is using "maw lum," a local form of entertainment, to encourage safer sex practices and to...

"AIDS: A Community Commitment" is the theme of World AIDS Day 1992. (December 1) (World Health Organization)
April 27, 1992... WHO The World Health Organization (WHO) has declared that World AIDS Day 1992 will focus on the pivotal role communities can and must play in taking up the global AIDS challenge. World AIDS Day, observed every year on December 1,...

National training center for professional AIDS education opens in Boston. (National Training Center for Drug-Exposed and HIV-Infected Children and Their Families) (The Foundation for Children with AIDS)
April 27, 1992... The Foundation for Children With AIDS The Foundation for Children With AIDS (FCWA) has introduced a new program to provide nationwide training and technical assistance to teachers, healthcare providers and other professionals who serve,...

Mice developed could mimic human immune system. (Massachusetts Institute of Technology)
April 27, 1992... Massachusetts Institute of Technology Scientists at the Massachusetts Institute of Technology's Center for Cancer Research have created mice with severely limited immune systems that could serve as recipients for human bone-marrow...

Coordinate regulation of serum immunoglobulins and IgG subclasses in human immunodeficiency virus (HIV) infection. (Research Report)
April 27, 1992... AUTHORS: S.M. Schnipper, C.B. Small and D.L. Rosenstreich. Department of Medicine, Albert Einstein College of Medicine, Bronx, New York. According to an abstract submitted by the authors to a joint meeting of the Association for...

The full-length TAT protein of HIV-2 can trans-activate HIV-1. (Research Report)
April 27, 1992... AUTHORS: S.E. Tong, A. Baur, X. Lu, E. Peck and B.M. Peterlin. University of California at San Francisco, Department of Medicine, SF VAMC and HHMI, San Francisco, California. According to an abstract submitted by the authors to a joint...

Antibody mediated enhancement of HIV-1 infection of an Epstein-Barr transformed B-cell line is CD4 dependent. (Research Report)
April 27, 1992... AUTHORS: H.S.L.M. Nottet, I. Janse, N.M. de Vos, L.J. Bakker, J.A.G. van Strijp, M.R. Visser and J. Verhoef. Eijkman-Winkler Institute for Medical Microbiology, University Hospital Utrecht, Utrecht, The Netherlands. According to an...

Human immunodeficiency virus (HIV) infection among patients of a dentist with AIDS. (Research Report)
April 27, 1992... AUTHORS: G. Dickinson, A. Bisno, R. Morhart, N. Klimas and J. Laracuente. Miami VA Medical Center and University of Miami School of Medicine, Miami, Florida. According to an abstract submitted by the authors to a joint meeting of the...

Comparison of clinical manifestations of HIV-1 disease between IVDUs and gay/bisexual men. (intravenous drug users) (Research Report)
April 27, 1992... AUTHORS: J. Palenicek, K. Nelson, S. Cohn, S. Rubb, A. Munoz, D. Vlahov and A. Saah. Department of Epidemiology, The Johns Hopkins School of Public Health and Hygiene, Baltimore, Maryland. According to an abstract submitted by the...

Population-based assessment of Listeria monocytogenes meningitis and bacteremia in metropolitan patients with human immunodeficiency virus. (Research Report)
April 27, 1992... AUTHORS: R.L. Jurado, E. Pereira, R.C. Harvey, A. Schuchat, J. Wenger, M.M. Farley and D.S. Stephens. Department of Medicine, Emory University, VA Medical Center and U.S. Centers for Disease Control, Atlanta, Georgia. According to an...

Mycobacterium tuberculosis activates expression of the human immunodeficiency virus. (Research Report)
April 27, 1992... AUTHORS: M.M. Lederman, D. Georges, S.L. Zeichner, J.C. Alwine and Z. Toossi. Case Western Reserve University, Cleveland, Ohio, and University of Pennsylvania, Philadelphia. According to an abstract submitted by the authors to a joint...

In vivo T-cell ablation by a holo-immunotoxin directed at human CD3. (Periodical Report)
April 27, 1992... SOURCE: Proceedings of the National Academy of Sciences, April 1992;89(7):2585-2589. An immunotoxin capable of killing both activated and resting T cells could be tested in animal models as an experimental AIDS therapy, murine studies...

Biogenic amines and metabolites in CSF from patients with HIV infection. (cerebrospinal fluid) (Periodical Report)
April 27, 1992... SOURCE: Biogenic Amines, 1992;8(5):293-298. HIV infection appears to inhibit serotonin metabolism, German researchers report. E. Sofic and colleagues of the University of Wurzburg, Germany, measured cerebrospinal fluid (CSF)...

Parenteral and sexual transmission of human immunodeficiency virus in intravenous drug users - a study of seroconversion. (Periodical Report)
April 27, 1992... SOURCE: American Journal of Epidemiology, 1992;135(3):225-233. An Italian study confirms that parenteral transmission is the principal means of HIV transmission among users of intravenous drugs. Researchers A. Nicolosi and...

Importance of endogenous tumor necrosis factor-alpha and gamma-interferon in host resistance against Pneumocystis carinii infection. (Periodical Report)
April 27, 1992... SOURCE: Infection and Immunity, April 1992;60(4):1279-1284. Tumor necrosis factor alpha (TNF-alpha) appears to be an important factor in host resistance to Pneumocystis carinii infection, murine studies show. W.X. Chen and...

Neurological complications of HIV-1-seropositive internal medicine inpatients in Kinshasa, Zaire. (Periodical Report)
April 27, 1992... SOURCE: Journal of Acquired Immune Deficiency Syndromes, April 1992;5(4):333-340. Neurological complications of HIV infection in Zairian patients are similar to those seen in industrialized nations, a study of hospital patients in...

Susceptibility of HIV-1 isolates to zidovudine - correlation between widely applicable culture test and PCR analysis. (polymerase chain reaction) (Periodical Report)
April 27, 1992... SOURCE: Journal of Acquired Immune Deficiency Syndromes, April 1992;5(4):359-364. The polymerase chain reaction (PCR) technique can be used to determine the susceptibility of virtually any patient isolate of HIV-1 to zidovudine (AZT),...

Current trends: public health uses of HIV-infection reports - South Carolina, 1986-1991. (Periodical Report)
April 27, 1992... SOURCE: Morbidity and Mortality Weekly Report, April 16, 1992. "In the United States, public health officials use AIDS surveillance data to monitor trends, manage resources within communities, and identify specific needs of special...

Smoking linked to HIV risk. (Haiti)
April 20, 1992... Haiti A study of Haitian women shows that moderate cigarette smokers are 3.4 times more likely than nonsmokers to have HIV infection. This link between smoking and risk of HIV infection persists even when the analysis takes into...

Panel appointed to probe theory on AIDS origin. (Tom Curtis' theory that Hilary Koprowski's polio vaccine was contaminated by a monkey virus) (Wistar Institute)
April 20, 1992... Wistar Institute A panel of six scientists has been appointed to evaluate a theory that AIDS originated more than 30 years ago in a batch of polio vaccine prepared at the Wistar Institute and distributed in Africa, the institute...

Experimental drug may block common AIDS infection. (rifabutin for Mycobacterium avium complex) (U.S. Food and Drug Administration )
April 20, 1992... U.S. FDA An experimental drug cleared by the U.S. Food and Drug Administration (FDA) for severe AIDS cases may delay or block a blood infection found in people with advanced stages of the disease. Preliminary results with the...

Early AZT treatment for HIV prolongs survival. (zidovudine) (Johns Hopkins School of Hygiene and Public Health)
April 20, 1992... Johns Hopkins School of Hygiene and Public Health An investigation led by Johns Hopkins Public Health researchers finds that early use of zidovudine (AZT) and preventive drugs for AIDS-related pneumonia (PCP prophylaxis) prolongs life...

Drug review initiatives announced. (U.S. Food and Drug Administration)
April 20, 1992... U.S. FDA Vice President Dan Quayle and U.S. Department of Health and Human Services (HHS) Secretary Louis W. Sullivan, M.D., announced that four initiatives are being implemented by the U.S. Food and Drug Administration (FDA) to speed...

Liability fears slow AIDS vaccine research, study shows. (report in the journal "Science")
April 20, 1992... United States Fear of being sued by patients is slowing and even stopping some AIDS vaccine research, according to the journal Science. The article, published in the April 10, 1992, issue of the journal Science, reports that some...

Activists protest against proposed AIDS vaccine trials. (India)
April 20, 1992... India Indian activists assert that the World Health Organization (WHO) is selectively using developing countries as "guinea pigs" for controversial vaccine trials. At a sit-in protest outside WHO's Southeast Asia regional office,...

Controversy brews over blood testing for HIV-2. (Washington, D.C.)
April 20, 1992... Washington, D.C. Only a few U.S. blood centers are testing for a rare but spreading strain of HIV despite fears that it could slip into the nation's blood supply. More than 50,000 people in Europe, Africa, India, the former Soviet...

Health authorities rethinking AIDS testing for newborns. (testing without notifying parents of the results) (New Hampshire)
April 20, 1992... New Hampshire Some New Hampshire healthcare officials are joining colleagues nationally having second thoughts about keeping newborn AIDS tests secret from their parents. The New Hampshire Sunday News reported that 1,800 infants...

IX International Conference on AIDS announced. (Berlin, Germany)
April 20, 1992... Berlin Even as the AIDS research community prepares for July's VIII International Conference on AIDS in Amsterdam, The Netherlands, organizers have announced plans for the 1993 conference in Berlin, Germany. The IX International...

New effort against TB and multi-drug resistant TB. (tuberculosis) (American Foundation for AIDS Research)
April 20, 1992... AmFAR The American Foundation for AIDS Research (AmFAR) will mobilize resources to confront the growing tuberculosis (TB) crisis afflicting America's large cities, AmFAR officials announced. AmFAR will bring together leaders from the...

Ashe: people with AIDS shouldn't be stigmatized. (Arthur Ashe)
April 20, 1992... New York Arthur Ashe, who disclosed that he has AIDS, says his 5-year-old daughter knows he has the disease but doesn't really understand what it is. "She knows the word, and we tried to relate that to other sicknesses that she...

Federal response to teen AIDS called "national disgrace." (House Select Committee on Children, Youth and Families) (Washington, D.C.)
April 20, 1992... Washington, D.C. A congressional panel expressed alarm at the spread of AIDS among adolescents and condemned the federal government's response as "a national disgrace." It concluded that federal efforts are "underfunded,...

Voluntary AIDS testing facility needed. (Zimbabwe)
April 20, 1992... Zimbabwe Young Zimbabweans, ready to marry and start their own families, are desperate to know their HIV status before they make the move. But, nearly seven years after the first HIV case was diagnosed in Zimbabwe in 1985, the...

Officials say many AIDS cases may go unreported. (Mexico)
April 20, 1992... Mexico Low numbers of AIDS cases on the Mexican side of the U.S. border have healthcare workers worried that inaccurate statistics are being kept on the virus, a newspaper reports. Officials said that El Paso, with a population of...

Association of group specific component with HIV infection in African American and Caucasian populations. (Research Report)
April 20, 1992... Association of Group Specific Component with HIV AUTHORS: R.E. Lewis, M. Brackin, B. Brackin, M. Crawford and J.M. Cruse. Department of Pathology, University Medical Center, Jackson, Mississippi. According to an abstract...

New perspectives in the use of animal models for evaluation of compounds for AIDS therapy. (Research Report)
April 20, 1992... New Perspectives in the Use of Animal Models for AUTHORS: Badi M. Boulos, M.D., Ph.D., and Alfred von Smolinski, Ph.D. School of Public Health, and College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois. ...

Multi-frequency bio-impedance analysis (MFBIA) to estimate total body water (TBW) and extracellular water (ECW) in patients with AIDS. (Research Report)
April 20, 1992... Multi-Frequency Bio-Impedance Analysis (MFBIA) To AUTHORS: M. Mazariegos, D. Kotler, J. Ma, J. Wang, S. Burastero, J. Thornton, E. Leonard, A. Pilla, C. Pinto, S. Yasumura and R.N. Pierson, Jr. St. Luke's-Roosevelt Hospital, Columbia...

Prognostic significance of serum p24 antigen and p24 binding capacity in HIV infection. (Research Report)
April 20, 1992... AUTHORS: P. Nishanian, B. Hofmann, R. Detels and John L. Fahey. CIRID, University of California at Los Angeles School of Medicine, Los Angeles, California. According to an abstract submitted by the authors to the 1992 meeting of the...

Upregulation of interleukin-6 (IL-6) in HIV-infected human macrophages coinfected with Pneumocystis carinii (PC). (Research Report)
April 20, 1992... AUTHORS: O. Kandil, J.A. Fishman, R.M. Rose and H.G. Remold. New England Deaconess Hospital, Massachusetts General Hospital, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. According to an abstract...

IL-2-driven proliferation of spleen cells from murine AIDS mice. (Research Report)
April 20, 1992... AUTHORS: M.B. Zaleski, H.R. Thacore, R.K. Cunningham, I. Stadler, P. Zhou, S. Nakeeb and K. Chadha. State University of New York at Buffalo, Buffalo, New York, and RPMI, Buffalo, New York. According to an abstract submitted by the...

Impairment of monocyte function and class II antigen expression in HIV-I infected human macrophage hybridomas. (Research Report)
April 20, 1992... AUTHORS: K. Sverber, G. Hamrang, M.J. Louie, R. Banerjee and L. Mayer. Mount Sinai School of Medicine, New York, New York. According to an abstract submitted by the authors to the 1992 meeting of the Federation of American Societies...

The disposition of L-696,229, a potent and specific inhibitor of human immunodeficiency virus reverse transcriptase, in rats and rhesus monkeys. (Research Report)
April 20, 1992... AUTHORS: R.A. Halpin, L.A. Geer, D.W. Wyatt, K.P. Vyas, M. Hichens and S. Vickers. Merck Sharp & Dohme Research Laboratories, Department of Drug Metabolism, West Point, Pennsylvania. According to an abstract submitted by the authors...

Surrogate markers in AIDS: where are we? Where are we going? (Periodical Report)
April 20, 1992... SOURCE: Annals of Internal Medicine, April 1, 1992;116(7):599-601. Although there is an "intensive" search for surrogate markers, clinical outcomes must still be used to evaluate clinical trials of AIDS therapies, report two researchers...

Specific antibody responses to synthetic peptides of HIV-1 p17 correlate with different stages of HIV-1 infection. (Periodical Report)
April 20, 1992... SOURCE: Journal of Acquired Immune Deficiency Syndromes, April 1992;5(4):382-390. The loss of antibodies to specific HIV-1 p17 epitopes is a sensitive predictor of disease progression, a study suggests. Jian-Dong Jiang and J....

Inactivated whole-virus vaccine derived from a proviral DNA clone of simian immunodeficiency virus induces high levels of neutralizing antibodies and confers protection against heterologous challenge. (Periodical Report)
April 20, 1992... SOURCE: Proceedings of the National Academy of Sciences, March 15, 1992;89(6):2175-2179. The renowned genetic variability of HIV may not be an insurmountable obstacle to the development of an effective HIV vaccine, animal studies...

Nonrandom distribution of gp120 N-linked glycosylation sites important for infectivity of human immunodeficiency virus type 1. (Periodical Report)
April 20, 1992... SOURCE: Proceedings of the National Academy of Sciences, March 15, 1992;89(6):2213-2217. Vaccines containing gp120 stripped of its protective sugar coating might be more effective than vaccines based on the entire HIV gp120 envelope...

HIV infection in patients over 55 years of age. (Periodical Report)
April 20, 1992... SOURCE: Journal of Acquired Immune Deficiency Syndromes, April 1992;5(4):348-355. HIV disease progresses more rapidly and aggressively in older patients, a Canadian study indicates. University of Toronto researchers Santiago...

Comparative trial of dapsone versus trimethoprim/sulfamethoxazole for primary prophylaxis of Pneumocystis carinii pneumonia. (Periodical Report)
April 20, 1992... SOURCE: Journal of Acquired Immune Deficiency Syndromes, April 1992;5(4):341-347. Dapsone and trimethoprim-sulfamethoxazole (TMP/SMX) are both effective in preventing a first episode of Pneumocystis carinii pneumonia (PCP) in...

Record numbers register for Harvard-Amsterdam conference. (VIII International Conference on AIDS)
April 13, 1992... VIII International Conference on AIDS More than 6,000 AIDS experts from around the world have registered for the VIII international Conference on AIDS/III STD World Congress, Conference Chair Jonathan Mann announced. The conference,...

Anti-mycoplasma action of AZT disputed. (England)
April 13, 1992... England AZT failed to kill or inhibit most strains of mycoplasma in a British study, calling into question the suggestion put forward earlier in 1992 that the drug's efficacy as an AIDS therapy is at least partly due to its...

Palliative radiation recommended for central nervous system lymphomas. (New York Hospital-Cornell Medical Center)
April 13, 1992... New York Hospital-Cornell Medical Center Radiation therapy should be considered for AIDS patients with central nervous system (CNS) symptoms who fail therapy for toxoplasmosis, suggest physicians at the New York Hospital-Cornell...

TB epidemic worsening, Roper says. (Dr. William L. Roper; tuberculosis) (U.S. Centers for Disease Control)
April 13, 1992... U.S. CDC The nation's tuberculosis epidemic continues to expand and to stop it every community will have to hire workers who will make sure that infected people take their daily medications, the director of the U.S. Centers for Disease...

Health officials ready action plan against TB. (tuberculosis) (U.S. Centers for Disease Control)
April 13, 1992... U.S. CDC A national plan of action designed to deal with a developing epidemic of drug-resistant tuberculosis was unveiled at a two-day meeting of federal health officials that began April 2, 1992. The action plan formulated by...

Nurses report personal safety as primary concern. (Research and Polling Inc. telephone survey)
April 13, 1992... Research and Polling Inc. According to a nationwide telephone survey of 300 critical care nurses, including 100 oncology nurses, concern for their personal safety is the number one job-related worry. Nine out of ten stated they...

Redefinition of AIDS to overload health, support systems. (U.S. Centers for Disease Control)
April 13, 1992... U.S. CDC From San Francisco's Castro District to New York's Greenwich Village, the impending redefinition of AIDS by the U.S. government has triggered a tidal wave of fear and apprehension among patients, support groups and health...

Judge refuses to dismiss AIDS liability lawsuit. (Judge Raymond Broderick; Department of Health and Human Services definition of AIDS & HIV infection) (Pennsylvania)
April 13, 1992... Pennsylvania A U.S. federal judge has refused to dismiss a lawsuit that challenges the definition of AIDS and HIV infection used to determine Social Security disability payments. Senior U.S. District Judge Raymond Broderick rejected...

Magic Johnson reportedly threatens to quit AIDS commission. (U.S. National Commission on AIDS)
April 13, 1992... U.S. National Commission on AIDS Basketball star Magic Johnson says in an interview with a gay newspaper that he is so fed up with the administration's handling of the AIDS crisis that he has told President Bush he may quit his...

New Online Journal of Clinical Trials delayed. (American Association for the Advancement of Science)
April 13, 1992... An event billed as the advent of a new era in medical publications will be delayed by three months. The Online Journal of Clinical Trials was announced in 1991 by the American Association for the Advancement of Science (AAAS),...

World Bank helps finance AIDS control project. (India)
April 13, 1992... The Indian government will initiate a national AIDS prevention and control program, supported largely by an $84 million World Bank credit approved by the International Development Association, the World Bank's affiliate for concessionary...

AIDS-infected Burmese prostitutes injected with cyanide. (after they were deported back to Burma) (Thailand)
April 13, 1992... At least 25 AIDS-infected prostitutes were injected with cyanide in Burma after being deported from Thailand, a social worker and a news report said April 2, 1992. The incident has prompted Thai police to halt deportations of Burmese girls...

AIDS problem continues to hamper tourism industry. (Thailand)
April 13, 1992... Thailand has successfully dealt with the temporary setbacks to its booming tourism industry brought on by pollution, crime and infrastructure problems. But cleanliness campaigns and new expressways and rail systems have not helped to rid...

500,000 AIDS cases reported, but real number may be more. (World Health Organization)
April 13, 1992... Close to 500,000 cases of AIDS have so far been reported worldwide, but World Health Organization (WHO) officials estimate that the actual amount of people suffering from the disease is much greater. In its quarterly report, released March...

AIDS cases top 24,000 mark. (Brazil)
April 13, 1992... The number of confirmed cases of AIDS in Brazil has risen to 24,433, the Ministry of Health reported in Rio de Janeiro. Lair Guerra de Macedo, director of the ministry's department dealing with sexually contagious diseases, said 18 out of...

Review panel finds global AIDS agency hampered by failings. (United Nations Global Program on AIDS)
April 13, 1992... The global agency designed to combat AIDS is depicted in a confidential review as too rigid to adapt to local cultures, slow to meet urgent needs and ill-equipped to make best use of its experts. In the face of a widening epidemic, the...

AIDS Task Force faces uncertain future. (European Community)
April 13, 1992... The European Community (EC) AIDS Task Force (ATF) is facing an uncertain future as the EC revises its position on how to contribute to the global fight against the disease. The ATF, a non-profit organization formed in 1987 to implement and...

Pregnant women, their infants, at risk for genital herpes. (Stanford University)
April 13, 1992... One out of every 20 pregnant women enrolled in a study in Stanford, California, had an unsuspected risk of contracting herpes simplex virus type 2, the most common cause of genital herpes, from husbands who harbored the virus but had never...

Research grants and awards totalling over $2.5 million awarded. (American Foundation for AIDS Research)
April 13, 1992... The American Foundation for AIDS Research (AmFAR) announced it has funded 29 Basic Research projects and eight Scholar Awards, totalling $2,543,658. This latest cycle of funds continues AmFAR's commitment to understanding the complete...

Company provides grant to Project Inform. (Burroughs Wellcome)
April 13, 1992... Project Inform, a national HIV treatment information and advocacy organization, announced that it has been awarded a project grant from Burroughs Wellcome Company for $149,500 to upgrade its computer capabilities. The project grant...

State's top court okays religious representatives on AIDS councils. (New York)
April 13, 1992... New York's highest court ruled that it's legal for religious groups to be represented on school AIDS advisory boards. In a 5-2 ruling against the New York State School Boards Association, the state Court of Appeals upheld rulings by lower...

Company presents interim results of AIDS treatment clinical trials. (Passive Hyperimmune Therapy) (HemaCare Corporation)
April 13, 1992... Joshua Levy, M.D., medical director of HemaCare Corporation, Los Angeles, California, reported the six-month, interim results of the company's controlled, clinical trials of Passive Hyperimmune Therapy (PHT) to the 5th National Forum on...

Company begins study of Cytogam in AIDS patients. (MedImmune)
April 13, 1992... MedImmune Inc., Gaithersburg, Maryland, announced the start of a combined Phase I/II study of CytoGam, the company's cytomegalovirus (CMV) immune globulin, in patients with HIV infection. Retinitis due to CMV is the major cause of blindness...

Company files IND on GS 504. (Investigational New Drug application; small molecule nucleotide analog for treatment of cytomegalovirus infection) (Gilead Sciences)
April 13, 1992... Gilead Sciences announced that it has filed an Investigational New Drug (IND) application with the U.S. Food and Drug Administration (FDA) for the clinical evaluation of its drug candidate GS 504 in the treatment of cytomegalovirus (CMV)...

Companies agree to co-develop, co-promote drug. (sparfloxacin) (Warner-Lambert, Rhone-Poulenc Rorer)
April 13, 1992... Warner-Lambert Company and Rhone-Poulenc Rorer Inc. (RPR) announced an agreement that will allow RPR to co-develop and co-promote the advanced quinolone antibacterial sparfloxacin in the U.S. and Canada. Warner-Lambert will continue to...

Marketing of immunofluorescent test for HIV to begin. (Fluorognost) (Thermascan Inc.)
April 13, 1992... Detlev Baurs-Krey, chairman and CEO of Thermascan Inc. announced that the company's Fluorognost test for antibodies to HIV-1 in human serum or plasma will be ready for distribution to blood banks and private and public health laboratories by...

Company re-enters tuberculosis medication market. (isoniazid) (Duramed Pharmaceuticals)
April 13, 1992... Duramed Pharmaceuticals Inc., Cincinnati, Ohio, will re-enter the tuberculosis medication market with Isoniazid, the generic equivalent of the brand drug INH, Duramed chairman and president E. Thomas Arington announced. Arington also...

Metabolism of a new HIV-1 reverse transcriptase inhibitor, 3-2-(benzoxazol-2-YL)ethyl-5-ethyl-6-methylpyridin-2(1H)-one(L-696,229), in rat and liver slices. (Research Report)
April 13, 1992... AUTHORS: S.K. Balani, S.M. Pitzenberger, L.R. Kauffman, B.H. Arison, H.G. Ramjit, M.E. Goldman, J.A. O'Brien, J.M. Hoffman and A.D. Theoharides. Merck Sharp & Dohme Research Laboratories, West Point, Pennsylvania. According to an...