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AIDS Weekly back issues
AZT reduces brain lesions in AIDS patients. (zidovudine)
October 30, 1995... Zidovudine can significantly reduce the incidence of HIV induced brain lesions in AIDS patients if continued until death, according to a decade-long study from Norway. Several neuropathological studies have concluded that zidovudine treatment reduces the frequency of HIV induced brain...
OI prevention should be tailored to the individual.(patient with AIDS)(opportunistic infection)
October 30, 1995... One of the great difficulties facing people with AIDS is the enormous number of antimicrobial drugs they have to take every day. The toxicity, expense, and inconvenience of this shotgun approach to preventing life-threatening opportunistic infections (OIs) could be reduced by more rational...
Early findings confirmed: intermittent IL-2 increases CD4 counts.(interleukin-2)
October 30, 1995... Intermittent infusions of the cytokine interleukin 2 (IL-2) increase CD4 counts to normal levels in patients with HIV infection who have CD4 counts of more than 200 cells/(micro)L. These findings, based on a study that enrolled 60 volunteers, confirm earlier reports that 13 years of...
Drug resistance mutations could make HIV less - or more - deadly.
October 30, 1995... Anti-HIV drugs cannot eliminate the virus, but well chosen combinations could force it to become less deadly. People infected with HIV-1 don't harbor just one virus. Because of HIV's vast replicative capacity and its inherent tendency to mutate, HIV infection is characterized by the...
Can immune-based interventions alter the course of AIDS?
October 30, 1995... As researchers begin to unravel the complex web of interactions between HIV and the immune system, they hope to develop new strategies for delaying - or even preventing - the onset of AIDS. University of Colorado AIDS researcher Robert T. "Chip" Schooley noted that early laboratory studies...