Hepatitis Weekly articles from October 2003

Hepatitis Weekly archives from October 2003

The MagNA pure LC reduces laborious HCV sample preparation.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- The MagNA pure LC reduces laborious HCV sample preparation. According to a study from the United States, "the COBAS AMPLICOR system has played a major role in the transition of molecular...

The INNO-LiPA assay can quickly identify hepatitis B virus variants.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- The INNO-LiPA assay can quickly identify hepatitis B virus variants. "Hepatitis B virus (HBV) genotypes may influence HBeAg seroconversion rates, mutational patterns in the precore (PC) and core...

Limitin is similar to but distinct from interferon-alpha as hepatitis C therapy.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Limitin is similar to but distinct from interferon-alpha as hepatitis C therapy. According to recent research from Japan, "limitin has sequence homology with alpha interferon (IFN-alpha) and...

Adenovirus-mediated interferon-alpha gene transfer blocks HCV replication.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Adenovirus-mediated interferon-alpha gene transfer blocks HCV replication. "Recently we reported that on-site interferon (IFN)-alpha production in the liver using an adenovirus vector can achieve a...

Thioredoxin transfection protects liver cells from apoptosis and necrosis.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Thioredoxin transfection protects liver cells from apoptosis and necrosis. "A recombinant adenovirus vector containing the human thioredoxin (TRX) gene was constructed using the Cre-loxP...

Subclinical hepatitis E virus prevails among humans and swine in Korea.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Subclinical hepatitis E virus prevails among humans and swine in Korea. "The swine hepatitis E virus (HEV) is considered to be a new zoonotic agent due to its close genomic resemblance to the human...

Pretreatment HCV hypervariable region 1 status predicts treatment outcomes.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Pretreatment HCV hypervariable region 1 status predicts treatment outcomes. "The heterogeneity of hypervariable region 1 (HVR1), located at the amino terminus of the E2 envelope, may be involved in...

Brazilian dialysis units are implicated in viral hepatitis transmission.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Brazilian dialysis units are implicated in viral hepatitis transmission. According to a study from Brazil, "a survey was conducted in the hemodialysis population of the state of Tocantins, Brazil,...

Hepatitis vaccine approved for sale in Argentina.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Corixa Corporation (CRXA) announced the Argentinean approval of Supervax, Berna Biotech's prophylactic vaccine containing Corixa's synthetic RC-529 adjuvant, for the prevention of Hepatitis B infection....

Risk posed by discarded needles and syringes.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Research shows that both the public and workers in inner-city parks and playgrounds are at risk of being exposed to blood-borne viruses such as hepatitis B or C through discarded needles and/or...

Normal and tumor human and murine liver NKT cells are dissimilar.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Normal and tumor human and murine liver NKT cells are dissimilar. "A major group of murine NK T (NKT) cells express an invariant Valpha14Jalpha18 T-cell receptor alpha-chain specific for glycolipid...

Monoclonal antibody to activated murine lymphocyte domain blocks liver damage.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Monoclonal antibody to activated murine lymphocyte domain blocks liver damage. According to scientists writing in the Journal of Experimental Medicine, "we earlier found that a rat monoclonal...

Hypotension-related liver disease clears upon hemodynamic support.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Hypotension-related liver disease clears upon hemodynamic support. "Ischemic hepatitis or shock liver is defined as an extensive hepatocellular necrosis associated with a decrease in hepatic...

Levin named to scientific advisory board at infectious disease firm.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Aethlon Medical, Inc., (AEMD) announced that Nathan W. Levin, MD, has been appointed to the company's science advisory board. Levin is the medical and research director of the Renal Research...

Product approved to treat primary humoral immune deficiency disease.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Results from the largest clinical study on licensure of immune globulin intravenous (IGIV) in primary humoral immune deficiency disease (PI) demonstrate the excellent efficacy, safety, and tolerability...

Hepatitis B virus X protein disturbs calcium signals to stimulate apoptosis.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Hepatitis B virus X protein disturbs calcium signals to stimulate apoptosis. "The hepatitis B virus X protein (HBx) is a multifunctional protein, acting on different targets (e. g. transcription...

Hepatitis C on the increase among injecting drug users.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Research carried out by the U.K. Health Protection Agency and Imperial College London shows that levels of hepatitis C are increasing among those who have recently started injecting drugs. Using...

Hepatitis C virus subgenomes replicate in nonhepatic human and murine cells.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus subgenomes replicate in nonhepatic human and murine cells. "The hepatitis C virus (HCV) pandemic affects the health of more than 170 million people and is the major indication for...

Hepatitis B virus X protein triggers survival signals by activating enzyme.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Hepatitis B virus X protein triggers survival signals by activating enzyme. "We have previously shown that transactivation-proficient hepatitis virus B X protein (HBx) protects Hep 3B cells from...

Recombinant variants protect against CTL escape and viral persistence in mice.
October 6, 2003... 2003 OCT 6 - (NewsRx.com & NewsRx.net) -- Recombinant variants protect against CTL escape and viral persistence in mice. According to a study from the United States, "cytotoxic T lymphocyte (CTL) escape mutations have been identified in...

Targeted cleavage of HEV RNA by hammerhead ribozymes blocks replication.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- Targeted cleavage of HEV RNA by hammerhead ribozymes blocks replication. "The 3' end of hepatitis E virus (HEV) contains cis-acting regulatory element, which plays an important role in viral...

Liver inoculation with synthetic RNA causes GB virus B persistence in tamarins.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- Liver inoculation with synthetic RNA causes GB virus B persistence in tamarins. According to recent research published in the journal Proceedings of the National Academy of Sciences USA, "progress...

Surface cavities of alpha(1)-antitrypsin could be targeted for liver therapy.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- Surface cavities of alpha(1)-antitrypsin could be targeted for liver therapy. "Conformational diseases are caused by a structural rearrangement within a protein that results in aberrant...

Bone marrow stem-cell transplants may be options for clearing hepatitis B virus.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- Bone marrow stem-cell transplants may be options for clearing hepatitis B virus. "Carriers of hepatitis B virus (HBV) who require allogeneic hematopoietic stem cell transplantation are at increased...

Workplace exposure to hepatitis C virus calls for timely management.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- Workplace exposure to hepatitis C virus calls for timely management. According to recent research from Australia, "the increasing rate of hepatitis C virus (HCV) infection in the community means...

GB virus-B may be a viral surrogate for testing hepatitis C therapy.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- GB virus-B may be a viral surrogate for testing hepatitis C therapy. According to a study from the United States, "the GB virus-B (GBV-B) nonstructural protein 513 (NS5B) encodes an RNA-dependent...

Plant compounds from Stylogne cauliflora block hepatitis C virus protease.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- Plant compounds from Stylogne cauliflora block hepatitis C virus protease. According to a study from the United States, "the 70% aqueous ruethanolic extract of the Peruvian plant Stylogne...

Tumor suppressor genes in hepatocellular carcinoma have aberrant profiles.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- Tumor suppressor genes in hepatocellular carcinoma have aberrant profiles. "Hepatocellular carcinoma (HCC) is one of the most fatal human malignancies, but the molecular mechanisms of...

Mosaic particles of hepatitis B virus protein are homo- and heterodimers.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- Mosaic particles formed by wild-type hepatitis B virus core protein and its deletion variants consist of both homo- and heterodimers. "Co-expression in Escherichia coli of wild-type (wt) hepatitis...

Import of HBV capsids through nuclear basket observed.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- The import of HBV capsids through the nuclear basket has been observed. "While studying the import of the hepatitis B virus genome into the nucleus of permeabilized tissue culture cells,"...

UNICEF launches emergency vaccination campaign in Peru.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- The United Nations Children's Fund (UNICEF) has launched an emergency vaccination campaign against hepatitis B for two ethnic groups in a remote region of the Peruvian Amazon, whose existence could be...

Duke, Johns Hopkins to lead first comparative trial of therapies.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- Researchers from Duke University Medical Center and the Johns Hopkins University School of Medicine will lead the first ever direct comparison of the two leading treatments for hepatitis C infection, a...

Adenoviral infection boosts tumor necrosis factor tolerance to halt hepatitis.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- Adenoviral infection boosts tumor necrosis factor tolerance to halt hepatitis. According to recent research published in the Journal of Immunology, "effects of adenoviral infection on in vivo...

Antifungal in vivo efficacy data presented at ICAAC.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- Genelabs Technologies, Inc., (GNLB) announced that in vivo efficacy studies on the company's novel antifungal preclinical candidate compound GL48656 were presented at the 43rd Interscience Conference...

Europe produces guidelines for preventing worker to patient hepatitis infection.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- Europe has produced guidelines for preventing worker to patient viral hepatitis infections. According to published research from Scotland, "the transmission of viral hepatitis from health care...

Cytosolic carbonic anhydrase is differentially expressed in human liver cancer.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- Cytosolic carbonic anhydrase is differentially expressed in human liver cancer. "Cytosolic carbonic anhydrases (CAs), including CAI, CAII and CAIII are present in normal hepatocytes. This study was...

Tumor necrosis factor and galactosamine stimulate bilirubin overexpression.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- Tumor necrosis factor and galactosamine stimulate bilirubin overexpression. "Application of tumor necrosis factor (TNF) in combination with galactosamine (GalN) in mice causes severe apoptosis of...

The hepatitis C core protein C-terminal region modulates apoptotic signaling.
October 13, 2003... 2003 OCT 13 - (NewsRx.com & NewsRx.net) -- The hepatitis C core protein C-terminal region modulates apoptotic signaling. "Hepatitis C virus (HCV) is remarkable for its ability to establish persistent infection. Studies suggest that HCV core...

High body mass index heightens risk for nonresponse to therapy for hepatitis C.
October 20, 2003... 2003 OCT 20 - (NewsRx.com & NewsRx.net) -- High body mass index heightens risk for nonresponse to therapy for hepatitis C. "The aim of this study was to determine if body mass index (BMI) was an independent predictor of response to...

Pregnancy and parturition influence chronic hepatitis C infection in females.
October 20, 2003... 2003 OCT 20 - (NewsRx.com & NewsRx.net) -- Pregnancy and parturition influence chronic hepatitis C infection in females. "It is unclear whether pregnancy has any influence on chronic hepatitis C virus (HCV) infection. The aim of this study...

Early virologic response with peginterferon alfa heralds sustained response.
October 20, 2003... 2003 OCT 20 - (NewsRx.com & NewsRx.net) -- Early virologic response with peginterferon alfa heralds sustained response. According to a study from the United States, "interferon-based regimens for the treatment of chronic hepatitis C have...

Using untreated waste water for irrigation increases worker risk for hepatitis E.
October 20, 2003... 2003 OCT 20 - (NewsRx.com & NewsRx.net) -- Using untreated waste water for irrigation increases worker risk for hepatitis E. According to recent research from Turkey, "untreated waste water usage in agriculture is an important...

Clinician attitudes impact treatment outcomes for drug users with hepatitis C.
October 20, 2003... 2003 OCT 20 - (NewsRx.com & NewsRx.net) -- Clinician attitudes impact treatment outcomes for drug users with hepatitis C. According to recent research from Australia, "the hepatitis C virus (HCV) is a common infection among injecting drug...

Hepatitis C patients who need liver retransplantations have worse outcomes.
October 20, 2003... 2003 OCT 20 - (NewsRx.com & NewsRx.net) -- Hepatitis C patients who need liver retransplantations have worse outcomes. According to published research from the United States, "it is not known whether the outcome of liver retransplantation...

Entecavir reduces hepatitis B virus DNA in the livers of animal models.
October 20, 2003... 2003 OCT 20 - (NewsRx.com & NewsRx.net) -- Entecavir reduces hepatitis B virus DNA in the livers of animal models. According to a study from the United States, "entecavir (ETV), a cyclopentyl guanosine nucleoside analog, was evaluated in...

Hepatitis A exposure lowers risk.
October 20, 2003... 2003 OCT 20 - (NewsRx.com & NewsRx.net) -- Exposure to hepatitis A virus (HAV) may make you less likely to develop asthma - but only if you carry a particular version of a key gene, according to new research. Until about 1970, most...

MultiCell receives $1.5 million for XenoTech cell transfer.
October 20, 2003... 2003 OCT 20 - (NewsRx.com & NewsRx.net) -- MultiCell Technologies, Inc., (MultiCell), a wholly owned subsidiary of Exten Industries, Inc., (Exten) (EXTI), has completed the training and transfer of two cell lines to XenoTech, LLC, and has...

More evidence points to adoptive immunity as a means of clearing hepatitis B.
October 20, 2003... 2003 OCT 20 - (NewsRx.com & NewsRx.net) -- More evidence points to adoptive immunity as a means of clearing hepatitis B. "We report a 38-yr-old male with acute lymphocytic leukemia (ALL) whose serological tests for the hepatitis B virus...

Interferon-alpha therapy for chronic hepatitis C causes skin color changes.
October 20, 2003... 2003 OCT 20 - (NewsRx.com & NewsRx.net) -- Interferon-alpha therapy for chronic hepatitis C causes skin color changes. "Many types of skin disorders concomitantly occur with hepatitis C virus infection. These skin lesions may be induced or...

Perforin and granzyme B are differentially expressed in chronic hepatitis C.
October 20, 2003... 2003 OCT 20 - (NewsRx.com & NewsRx.net) -- Perforin and granzyme B are differentially expressed in chronic hepatitis C. "T lymphocytes have been reported to be the predominant inflammatory cells in the liver of patients with chronic...

Sporadic hepatitis E virus cases in Hokkaido, Japan appear to be food-borne.
October 20, 2003... 2003 OCT 20 - (NewsRx.com & NewsRx.net) -- Sporadic hepatitis E virus cases in Hokkaido, Japan appear to be food-borne. According to recent research published in the Journal of General Virology, "among ten patients who contracted sporadic...

Hepatitis A outbreak linked to blueberries in New Zealand.
October 20, 2003... 2003 OCT 20 - (NewsRx.com & NewsRx.net) -- An outbreak of hepatitis A has been linked to blueberry consumption in New Zealand. Scientists there described "the epidemiology, investigation and control of a hepatitis A (HAV) outbreak" in the...

Panel: Long-term efficacy of hepatitis A vaccination means no need for booster.
October 20, 2003... 2003 OCT 20 - (NewsRx.com & NewsRx.net) -- An international consensus panel has concluded that the hepatitis A primary vaccination course provides long-term immunity against the virus into adulthood, with no need for a booster vaccine for...

Excessive host response is a major cause of HAV-related liver failure.
October 20, 2003... 2003 OCT 20 - (NewsRx.com & NewsRx.net) -- Excessive host response is a major cause of HAV-related liver failure. According to a study from France, "fulminant hepatitis is a severe complication of hepatitis A virus infection. Its mechanism...

Enrollment completed for new hepatitis C therapy clinical trial.
October 20, 2003... 2003 OCT 20 - (NewsRx.com & NewsRx.net) -- SciClone Pharmaceuticals, Inc., (SCLN) has completed the planned enrollment of 500 patients in the first of its two phase III hepatitis C (HCV) clinical trials evaluating its lead immune...

First head-to-head study of hepatitis C therapies in planning.
October 20, 2003... 2003 OCT 20 - (NewsRx.com & NewsRx.net) -- Schering-Plough Corporation (SGP) announced plans to initiate a major clinical study involving 2,880 patients that, for the first time, will directly compare the two approved forms of pegylated...

Study: FK778 efficacious, well tolerated, safe in kidney transplant patients.
October 20, 2003... 2003 OCT 20 - (NewsRx.com & NewsRx.net) -- First clinical data presented at the 11th Congress of the European Society for Organ Transplantation in Venice suggest FK778, a novel compound with multiple mechanisms of action, is efficacious, well...

Cooperation between hepatitis C and B viruses leads to cellular transformation.
October 20, 2003... 2003 OCT 20 - (NewsRx.com & NewsRx.net) -- Cooperation between hepatitis C and B viruses leads to cellular transformation. According to a study from South Korea, "coinfection with hepatitis B virus (HBV) and hepatitis C Virus (HCV) is...

Testing of MB7133 begins.
October 20, 2003... 2003 OCT 20 - (NewsRx.com & NewsRx.net) -- Metabasis Therapeutics, Inc., (Metabasis) announced that it has begun clinical testing of MB7133, a liver-specific prodrug of the anticancer drug cytarabine. MB7133 was developed by Metabasis and...

The NS5A region of hepatitis C virus genotype 1b is flexible but stable.
October 20, 2003... 2003 OCT 20 - (NewsRx.com & NewsRx.net) -- The NS5A region of hepatitis C virus genotype 1b is flexible but stable. According to recent research published in the Journal of Medical Virology, "the quasispecies nature of hepatitis C virus...

IDN-6556 gets orphan drug designation.
October 20, 2003... 2003 OCT 20 - (NewsRx.com & NewsRx.net) -- Idun Pharmaceuticals, Inc., announced that the U.S. Food and Drug Administration (FDA) has granted orphan drug designation for the use of IDN-6556 to treat patients undergoing liver transplantation and...

Enrollment complete for phase III clinical trial for Ceplene.
October 20, 2003... 2003 OCT 20 - (NewsRx.com & NewsRx.net) -- Maxim Pharmaceuticals (MAXM) has completed enrollment for the confirmatory phase III trial of its lead drug candidate Ceplene (histamine dihydrochloride) in combination with Interleukin-2 (IL-2) for...

Better prenatal screening practices needed, especially among underserved women.
October 20, 2003... 2003 OCT 20 - (NewsRx.com & NewsRx.net) -- Although healthcare providers have a high compliance rate with long-standing prenatal screening recommendations for hepatitis B, syphilis, and rubella, improvements in prenatal testing and the delivery...

New cancer gene therapy restricts treatment to liver cancer cells.
October 20, 2003... 2003 OCT 20 - (NewsRx.com & NewsRx.net) -- New cancer gene therapy restricts treatment to liver cancer cells. "Suicide gene therapy combining herpes simplex virus thymidine kinase gene transfer and ganciclovir administration can be...

Prior hepatitis B virus infection links to liver cancer in hepatitis C patients.
October 20, 2003... 2003 OCT 20 - (NewsRx.com & NewsRx.net) -- Prior hepatitis B virus infection links to liver cancer in hepatitis C patients. "To clarify the clinical significance of prior hepatitis B virus (HBV) infection in the development of C-viral...

Repeated liver cell injury promotes tumorigenesis in HCV transgenic mice.
October 20, 2003... 2003 OCT 20 - (NewsRx.com & NewsRx.net) -- Repeated liver cell injury promotes tumorigenesis in HCV transgenic mice. "Although hepatitis C virus (HCV) is a well-known causative agent of hepatocellular carcinoma (HCC), the mechanism by which...

Mice lacking TNF alpha receptors resist fulminant liver injury and death.
October 20, 2003... 2003 OCT 20 - (NewsRx.com & NewsRx.net) -- Mice lacking TNF alpha receptors resist fulminant liver injury and death. According to recent research from Italy, "the liver is particularly susceptible to Fas-mediated cytotoxicity. Mice given an...

Communities within Yemen exhibit different rates of viral hepatitis.
October 20, 2003... 2003 OCT 20 - (NewsRx.com & NewsRx.net) -- Communities within Yemen exhibit different rates of viral hepatitis. "It is generally believed that hepatitis B (HBV) and C (HCV) viruses are highly prevalent in the Republic of Yemen. This study...

Small sample sets are useful for evaluating genetic variability in viruses.
October 20, 2003... 2003 OCT 20 - (NewsRx.com & NewsRx.net) -- Small sample sets are useful for evaluating genetic variability in viruses. "Among the experimental techniques available to study the genetic variability of RNA virus populations, the most...

Hepatitis B virus precore/core promoter variants thrive in the United States.
October 20, 2003... 2003 OCT 20 - (NewsRx.com & NewsRx.net) -- Hepatitis B virus precore/core promoter variants thrive in the United States. "Variants in the precore (G(1896)A) and core promoter (A(1762)T, G(1764)A) regions of hepatitis B virus (HBV) may be...

Hepatitis C virus patterns in Cameroon suggest West Africa diversification.
October 20, 2003... 2003 OCT 20 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus patterns in Cameroon suggest West Africa diversification. Hepatitis C virus isolate endemicity patterns in Cameroon are unique. According to a study from the United States,...

MARS alleviates neurological progression in liver disease-related coma.
October 27, 2003... 2003 OCT 27 - (NewsRx.com & NewsRx.net) -- MARS alleviates neurological progression in liver disease-related coma. "In our 3-year experience, we treated 63 patients with molecular adsorbent recirculating system (MARS). The patients were...

Interferon therapy prior to liver transplant curbs hepatitis C recurrence.
October 27, 2003... 2003 OCT 27 - (NewsRx.com & NewsRx.net) -- Interferon therapy prior to liver transplant curbs hepatitis C recurrence. According to published research from the United States, "an analysis of the National Institute of Diabetes and Digestive...

Creatine supplementation causes liver inflammation in mice but not rats.
October 27, 2003... 2003 OCT 27 - (NewsRx.com & NewsRx.net) -- Creatine supplementation liver inflammation in mice but not rats. "Creatine monohydrate (CrM) supplementation appears to be relatively safe based on data from short-term and intermediate-term...

No link between hepatitis C and non-Hodgkin lymphoma can be found in Turkey.
October 27, 2003... 2003 OCT 27 - (NewsRx.com & NewsRx.net) -- No link between hepatitis C and non-Hodgkin lymphoma can be found in Turkey. According to published research from Turkey, "hepatitis C virus (HCV) has been associated with several extrahepatic...

Suppression subtractive hybridization characterizes the genetics of cirrhosis.
October 27, 2003... 2003 OCT 27 - (NewsRx.com & NewsRx.net) -- Suppression subtractive hybridization characterizes the genetics of cirrhosis. "Pathogenic molecular pathways in cirrhotic liver diseases such as hepatitis C virus (HCV), autoimmune hepatitis (AIH)...

The 5' untranslated region of GB virus C highlights genotypic differences.
October 27, 2003... 2003 OCT 27 - (NewsRx.com & NewsRx.net) -- The 5' untranslated region of GB virus C highlights genotypic differences. According to a study from Germany, "GB virus C (GBV-C) is a virus that has been proposed as a member of the Flaviviridae...

U.S.-Russian initiative to intensify cooperation in fight against disease.
October 27, 2003... 2003 OCT 27 - (NewsRx.com & NewsRx.net) -- The U.S. Civilian Research and Development Foundation (CRDF) has announced an initiative to increase research collaborations with scientists from Russia on HIV/AIDS and related infections, including...

Apoptosis precedes necrosis in acetaminophen-induced liver injury.
October 27, 2003... 2003 OCT 27 - (NewsRx.com & NewsRx.net) -- Apoptosis precedes necrosis in acetaminophen-induced liver injury. "The role of apoptosis in acetaminophen (AAP)-induced hepatic injury was investigated. Six hours after AAP administration to...

HCV and HIV coat proteins collaboratively mediate hepatocyte IL-8 release.
October 27, 2003... 2003 OCT 27 - (NewsRx.com & NewsRx.net) -- The HCV and HIV envelope proteins collaboratively mediate IL-8 release by hepatocytes. According to recent research published in the Journal of Biological Chemistry, HCV "infects approximately 40%...

Seroepidemiology of hepatitis B virus in Addis Ababa reported.
October 27, 2003... 2003 OCT 27 - (NewsRx.com & NewsRx.net) -- A group of investigators report the transmission patterns and vaccine control levels of hepatitis B virus in Addis Ababa, Ethiopia. According to published research from Ethiopia and Kenya, "A...

Ribavirin has an inhibitory effect on HCV polymerase-mediated RNA synthesis.
October 27, 2003... 2003 OCT 27 - (NewsRx.com & NewsRx.net) -- Ribavirin has an inhibitory effect on HCV polymerase-mediated RNA synthesis. "Crotty et al. recently proposed the primary antiviral action of ribavirin to be that of a potent RNA mutagen (Crotty,...

Elevated gamma glutamyl in kava consumers doesn't reflect liver injury.
October 27, 2003... 2003 OCT 27 - (NewsRx.com & NewsRx.net) -- Elevated gamma glutamyl in kava consumers doesn't reflect liver injury. According to a study from Switzerland, "traditional aqueous kava extracts were the most probable cause of hepatitis in two...

Self-antibodies in hepatitis C patients suggest immune response cross reactions.
October 27, 2003... 2003 OCT 27 - (NewsRx.com & NewsRx.net) -- Self-antibodies in hepatitis C patients suggest immune response cross reactions. According to a study from England, "autoantibodies to smooth muscle (SMA) and nuclear components (ANA) arise in the...