Hepatitis Weekly articles from May 2004

Hepatitis Weekly archives from May 2004

Interferon-alpha stops the formation of liver cancer in animal models.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Interferon-alpha stops the formation of liver cancer in animal models. According to a study from Japan, "interferon (IFN)-alpha treatment is a common therapy for chronic viral hepatitis and...

Hepatitis C virus core protein intercepts p53 activity to halt apoptosis.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus core protein intercepts p53 activity to halt apoptosis. "The core protein of hepatitis C virus affects several biological functions of the host cells such as cellular growth and...

Chronic hepatitis C patients with type I personalities have more problems.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Chronic hepatitis C patients with type I personalities have more problems. According to a study from Japan, "this cross-sectional study examined the association between the severity of chronic...

Primary sclerosing cholangitis heightens odds for liver transplant rejection.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Primary sclerosing cholangitis heightens odds for liver transplant rejection. According to recent research from the United States, "acute cellular rejection (ACR) after liver transplantation occurs...

MyD88 protein suppresses hepatitis B virus replication.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- MyD88 protein suppresses hepatitis B virus replication. "Myeloid differential primary response protein (MyD88) is a critical component in the signaling cascade through Toll-like receptors (TLRs)...

Musk substitution doesn't alter the hepatoprotective actions of Pien Tze Huang.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Musk substitution doesn't alter the hepatoprotective actions of Pien Tze Huang. "Previous studies showed that Pien Tze Huang, a Chinese folk medicine well known for its therapeutic activity in...

A new assay is well-suited for routine detection of hepatitis B virus DNA.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- A new assay is well-suited for routine detection of hepatitis B virus DNA. "We report on the development of a fully automated real-time polymerase chain reaction (PCR) assay for the quantitative...

VScan HIV Rapid Test Kits placed in dispensaries in Southeast Asia.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Medical Services International, Inc., (MSITF) announced that its VScan HIV 1&2 Rapid Test Kits will now be carried in drugstores in Hong Kong. The Hong Kong distributor working with Medical Services...

Neither hepatitis B nor C viruses associate with vulval lichen planus.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Neither hepatitis B nor C viruses associate with vulval lichen planus. According to a study from England, "the aim of the study was to investigate the prevalence of hepatitis C (HCV) antibodies,...

Novel CD4+ T-helper lymphocyte epitope identified in hepatitis A virus.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Researchers have identified a novel CD4+ T-helper lymphocyte epitope in the VP3 protein of the hepatitis A virus. According to a study from Spain, "Prediction analysis of Th-cell epitopes in the...

Pre-emptive use of lamivudine prevents hepatitis B in breast cancer.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Preemptive use of lamivudine prevents reactivation of hepatitis B infection in breast cancer patients undergoing postoperative adjuvant chemotherapy. According to recent research from Taiwan,...

Hepatitis B vaccine decreases hepatitis B incidence in cohort of drug users.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- The incidence of hepatitis B infection has progressively decreased in a cohort of drug users followed over a period of 15 years due to anti-HBV vaccination. According to recent research from Italy,...

FDA approves Ribasphere 200 mg for chronic hepatitis C.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Three Rivers Pharmaceuticals, LLC, announced that the U.S. Food and Drug Administration (FDA) has granted marketing approval for its Ribasphere (Ribavirin capsules) 200 mg in combination with interferon...

FDA issues final approval for ribavirin capsules.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Par Pharmaceutical, Inc., the principal subsidiary of Pharmaceutical Resources, Inc. (PRX), announced that its marketing partner, Three Rivers Pharmaceuticals, has received final approval from the U.S....

Functional hepatitis C virus envelope glycoproteins characterized.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Scientists have characterized functional hepatitis C virus envelope glycoproteins. According to published research from France and the United States, "Hepatitis C virus (HCV) encodes two envelope...

Patients with liver disease report dissatisfaction with their doctors.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- More than 40% of patients with hepatitis C virus (HCV) in a new study reported communication problems with their physicians. The main problems patients cited were poor physician communication...

Preclinical study points to development of glucosylceramide.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Enzo Biochem, Inc., (ENZ) scientists recently presented results of a preclinical study in an animal model system evaluating one of the company's new immunomodulatory agents, glucosylceramide (GC), as a...

B lymphocytes produce normal signals despite hepatitis C virus infection.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- B lymphocytes produce normal signals despite hepatitis C virus infection. "To clarify whether some of the functions of B lymphocytes could be affected during hepatitis C virus (HCV) infection,...

Liver transplant for hepatocellular cancer is treatment for select few.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Liver transplant for hepatocellular cancer is a treatment for the select few. According to recent research from the United States, "Hepatocellular cancer (HCC) is increasing in incidence and liver...

Study: Combination of minimally invasive treatments as effective as surgery.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Results of a new study show that combining two minimally invasive interventional radiology treatments for liver cancer is as effective as surgery for treating single tumors up to 7 cm in diameter,...

Treatment delivers radioactive isotope directly into the liver with embolization.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Treatment options for patients with hepatocellular carcinoma, a type of liver cancer, are limited, and up to 90% of patients are not candidates for surgery. Although surgery offers the best chance...

Childhood hepatitis B e antigen seroconversion may be a risk for liver cancer.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Childhood hepatitis B e antigen seroconversion may be a risk for liver cancer. "We prospectively followed 426 children with chronic hepatitis B virus infection. During 6250 person-years, 2 boys...

Polypeptides in hepatitis B virus carriers correlate with disease status.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Polypeptides in hepatitis B virus carriers correlate with disease status. According to recent research published in the journal Proteomics, "analysis of the polypeptide profile in tissues, cells,...

Survey suggests lack of awareness heightens risk for STDs.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- New survey results unveiled by the American Social Health Association (ASHA) suggest that lack of awareness may put Americans at risk for contracting STDs. While an overwhelming majority surveyed...

Novel free radical scavengers improve outcomes after liver transplantations.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Novel free radical scavengers improve outcomes after liver transplantations. According to recent research from the United States, "cessation of blood flow to the liver is required during liver...

Hepatitis C virus NS3 protein displays significant genetic variability.
May 3, 2004... 2004 MAY 3 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus NS3 protein displays significant genetic variability. "Hepatitis C virus (HCV) variation in specific T-cell epitopes may represent a mechanism of viral persistence in chronic...

Murine hepatitis models can screen for Cav 1.3-specific therapy.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Murine hepatitis models can screen for Cav 1.3-specific therapy. "Dihydropyridine (DHP) type Ca2+ channel blocker (CCB) is effective for the treatment of hepatitis in man. L-type Ca2+ channel is a...

Vesicular stomatitis virus infusions staunch hepatocellular carcinoma in rats.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Vesicular stomatitis virus infusions staunch hepatocellular carcinoma in rats. According to a study from the United States, "hepatocellular carcinoma (HCC) is a lethal malignancy with poor...

Autoimmune liver disease patients show evidence of Helicobacter infection.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Autoimmune liver disease patients show evidence of Helicobacter infection. "Various Helicobacter species have been isolated from the stomach, intestinal tract and liver of a variety of mammalian...

Hepatitis B virus preS1 sequences stimulate squamous cell carcinoma antigen.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Hepatitis B virus preS1 sequences stimulate squamous cell carcinoma antigen. "A variant of the serpin squamous cell carcinoma antigen (SCCA) has been identified as a hepatitis B virus (HBV) binding...

Specific hepatitis B virus mutations predict liver cancer formation.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Specific hepatitis B virus mutations predict liver cancer formation. "A major risk factor for hepatocellular carcinoma (HCC) is hepatitis B virus (HBV), whose pathogenesis is exacerbated by the...

Interferon-alpha stimulates optic neuropathy in a chronic hepatitis C patient.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Interferon-alpha stimulates optic neuropathy in a chronic hepatitis C patient. "The authors describe one patient with essential thrombocytosis and one with chronic hepatitis C infection who...

Features of HIV- and hepatitis C-related APS described.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- The symptoms associated with APS in HIV and hepatitis C patients have been characterized. In a recent study, researchers in Spain "analyzed the spectrum of clinical features related to...

Squamous cell carcinoma antigen variants are overexpressed in liver cancer.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Squamous cell carcinoma antigen variants are overexpressed in liver cancer. According to recent research from Italy, "pathogenetic mechanisms of hepatocellular carcinoma (HCC) are still unclear and...

Home Access FDA-approved at-home tests to be distributed internationally.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Vencor International, Inc., (VNCO) is expanding its newly developed relationship with Home Access Health Corporation by entering into a Memorandum of Understanding to develop international channels of...

Primovist, a new MRI liver-contrast agent, approved in Sweden.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Schering, AG, Group, Germany (SHR) announced that the Swedish health authority MPA has granted marketing approval for its liver-imaging product Primovist (gadoxetic acid disodium). Primovist is...

Solid phase ELISA panels detect hepatitis B virus biomarkers in sera.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Solid-phase ELISA panels detect hepatitis B virus biomarkers in sera. According to a study from Greece, "immunoassays for the detection of hepatitis B virus (HBV) in biological samples were...

N-terminally PEGylated interferon-beta yields improved pharmacology.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- N-terminally PEGylated interferon-beta yields improved pharmacology. According to recent research published in the journal Protein Expression and Purification, "to identify potential new clinical...

Sphingomyelinase activity modulates the development of lethal hepatitis.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Sphingomyelinase activity modulates the development of lethal hepatitis. "S-adenosyl-L-methionine (SAM) is synthesized by methionine adenosyltransferases (MATs). Ablation of the liver-specific...

Antioxidant defense mechanisms stem non-alcoholic steatohepatitis progression.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Antioxidant defense mechanisms stem non-alcoholic steatohepatitis progression. "This comment discusses the study by Videla and colleagues in this issue of Clinical Science in which they have...

Claritin manufacturer posts $73 million first-quarter loss.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Struggling drugmaker Schering-Plough Corp. posted a $73 million first-quarter loss, as higher spending and tougher competition for key products slashed total U.S. revenues by 23%. The maker of...

Effect of HIV infection on NK cell inhibitory receptors clarified.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- The effect of HIV infection on NK cell receptor expression has been elucidated. In a recent study, researchers in the United States "examined the cell-surface expression of chemokine and natural...

Acute HIV infection linked to stable or reduced HBV loads.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Surprisingly, acute HIV infection appears to reduce HBV loads in hepatitis B patients. Scientists in Baltimore "hypothesized that acute infection with human immunodeficiency virus (HIV) would...

1-year results announced for Telbivudine hepatitis B treatment candidate.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Idenix Pharmaceuticals, Inc., presented 1-year data from a randomized, double-blind, multinational phase IIb clinical trial comparing treatment with telbivudine alone or treatment with a combination of...

Metabasis reports $1M milestone payment for remofovir.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Metabasis Therapeutics, Inc., (Metabasis) announced that Valeant Pharmaceuticals International has agreed to pay a $1 million milestone payment to Metabasis in recognition of a decision to initiate a...

New combination therapy studied in hepatitis B clinical trial.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- SciClone Pharmaceuticals (SCLN) announced an ongoing randomized placebo-controlled clinical trial in Taiwan using a high dose of Zadaxin in combination with lamivudine, the most widely used treatment...

New data support Hepsera's long-term efficacy against chronic hepatitis B.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Gilead Sciences (GILD) announced 144-week data from a clinical trial (Study 438) of its oral antiviral drug Hepsera (adefovir dipivoxil 10 mg) in patients with hepatitis B "e" (envelope)...

Study results highlight therapies for unmet needs in hepatitis C treatment.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- New data for proprietary investigational antiviral therapies for hepatitis C virus (HCV) infection being developed by Vertex Pharmaceuticals Incorporated (VRTX) were presented at the Annual Meeting for...

Interferon/ribavirin therapy can be safe, but sustained response remains low.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Patients who are infected with both HIV and hepatitis C (HCV) can be safely treated for the latter infection with a combination of ribavirin (RBV) and interferon alpha-2b (IFN), according to a new...

Mechanical massage enhances liver cell gene transfer in the mouse.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Mechanical massage enhances liver cell gene transfer in the mouse. "Many metabolic diseases are caused by defects in the metabolic pathways in the liver. Others result from the absence of specific...

Company announces positive results in bioavailability study for Icatibant.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Jerini reported positive results from a bioavailability study of its lead compound Icatibant to assess the pharmacokinetics, safety, and local tolerability of subcutaneous formulation in comparison...

Indoleamine 2,3-dioxygenase plays a role in interferon-alpha-induced depression.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Indoleamine 2,3-dioxygenase plays a role in interferon-alpha-induced depression. According to a study from the Netherlands, "the mechanisms by which administration of interferon-alpha induces...

Safety syringes market continues to grow.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- With a total world market exceeding 12 billion units annually, syringe-based injection devices remain second only to oral drugs for the delivery of pharmaceuticals, reports Greystone Associates. ...

Oxidative stress rises with non-alcoholic fatty liver disease progression.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Oxidative stress rises with non-alcoholic fatty liver disease progression. "Oxidative stress is implicated in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). In the present study,...

Bioartificial liver reduces mortality by 44% in acute liver-failure patients.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- In a major study conducted at 20 centers in the United States and Europe, a bioartificial liver developed by researchers at Cedars-Sinai Medical Center reduced mortality significantly among patients...

Researchers report a possible technique for expanding the donor liver pool.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Heat shock preconditioning (HPc) in a rat fatty liver model resulted in much higher organ survival rate, researchers report. "Fatty liver is a common predisposing risk factor for postoperative...

DNA virus-like particles elicit immune responses by oral administration.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- DNA vaccine-encapsulated virus-like particles derived from an orally transmissible virus stimulate mucosal and systemic immune responses by oral administration. According to a study from Japan,...

Andaman and Nicobar Islands tribal school children harbor HBV infections.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Andaman and Nicobar Islands tribal school children harbor HBV infections. According to a study from India, "a sero-survey to assess the prevalence of hepatitis B virus (HBV)infection was carried...

United States chickens have subclinical avian hepatitis E virus infections.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- United States chickens have subclinical avian hepatitis E virus infections. "Avian hepatitis E virus (HEV), a novel virus identified from chickens with hepatitis-splenomegaly (HS) syndrome, is...

Hepatitis C virus core protein impedes cell cycle progression.
May 10, 2004... 2004 MAY 10 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus core protein impedes cell cycle progression. According to researchers in Japan, "we investigated how the hepatitis C virus (HCV) core protein affects the cell cycle profile and...

Unique gene sets distinguish cirrhosis patients with a risk for liver cancer.
May 17, 2004... 2004 MAY 17 - (NewsRx.com & NewsRx.net) -- Unique gene sets distinguish cirrhosis patients with a risk for liver cancer. According to published research from the United States, "several types of aggressive cancers, including hepatocellular...

Pioglitazone shows promise for treating non-alcoholic steatohepatitis.
May 17, 2004... 2004 MAY 17 - (NewsRx.com & NewsRx.net) -- Pioglitazone shows promise for treating non-alcoholic steatohepatitis. "Nonalcoholic steatohepatitis (NASH) is a common chronic liver disease for which there is no known effective therapy. A...

Hepatitis C patients have fibrosis progression when T cell response falters.
May 17, 2004... 2004 MAY 17 - (NewsRx.com & NewsRx.net) -- Hepatitis C patients have fibrosis progression when T cell response falters. According to a study from Egypt, "the kinetics of intrahepatic hepatitis C virus (HCV)-specific CD4+ T cell responses...

New transgenic mice could serve as models for hepatitis B-related liver cancer.
May 17, 2004... 2004 MAY 17 - (NewsRx.com & NewsRx.net) -- New transgenic mice could serve as models for hepatitis B-related liver cancer. According to a study from the Peoples Republic of China, "hepatocellular carcinoma (HCC) affects males in a...

Erythropoietin may benefit patients with post-liver-transplant anemia.
May 17, 2004... 2004 MAY 17 - (NewsRx.com & NewsRx.net) -- Erythropoietin may benefit patients with post-liver-transplant anemia. According to a study from the United States, "anemia is common after liver transplantation, with the incidence ranging from...

Beliefs about HCV status affect drug users' health-related quality of life.
May 17, 2004... 2004 MAY 17 - (NewsRx.com & NewsRx.net) -- Beliefs about HCV status affect drug users' health-related quality of life. According to recent research published in the journal Hepatology, "this study assessed the effect of chronic hepatitis C...

Genelabs Technologies completes sale of diagnostics business.
May 17, 2004... 2004 MAY 17 - (NewsRx.com & NewsRx.net) -- Genelabs Technologies, Inc., (GNLB) has completed the sale of its diagnostics business to MP Biomedicals, LLC. In the transaction, Genelabs sold all of the outstanding common and preferred stock...

Drug resistant hepatitis B virus genotypes have different mutational patterns.
May 17, 2004... 2004 MAY 17 - (NewsRx.com & NewsRx.net) -- Drug resistant hepatitis B genotypes have different mutational patterns. "Viral differences among lamivudine resistant hepatitis B (HBV) genotypes have not been yet investigated. Therefore, we...

Specific HBV DNA sequences predict a patient's response to lamivudine.
May 17, 2004... 2004 MAY 17 - (NewsRx.com & NewsRx.net) -- Specific HBV DNA sequences predict a patient's response to lamivudine. According to recent research from the United States, "numerous studies have shown that resistance to long-term lamivudine...

Development, license agreement signed for phase II hepatitis B compound.
May 17, 2004... 2004 MAY 17 - (NewsRx.com & NewsRx.net) -- Anadys Pharmaceuticals, Inc., (ANDS) and LG Life Sciences (68870) of Seoul, Korea, announced that they have entered into an agreement to develop for potential commercialization LB80380 (ANA380), a...

Biopharmaceutical company reports strong first-quarter sales.
May 17, 2004... 2004 MAY 17 - (NewsRx.com & NewsRx.net) -- Nabi Biopharmaceuticals (NABI) announced its financial results for the first quarter ended March 27, 2004. Strong first-quarter sales of biopharmaceutical products drove a 36% increase in gross...

Viread maker reports first quarter total revenues of $309 million, up 87%.
May 17, 2004... 2004 MAY 17 - (NewsRx.com & NewsRx.net) -- Gilead Sciences, Inc., (GILD) announced its first quarter results. Total revenues for the first quarter of 2004 were $309.1 million, up 87%, compared to total revenues of $165.1 million for the...

Novel array links shotgun sequencing with transcript mapping.
May 17, 2004... 2004 MAY 17 - (NewsRx.com & NewsRx.net) -- A novel genomic array links large-scale "shotgun" sequencing with transcript mapping. "To facilitate transcript mapping and to investigate alterations in genomic structure and gene expression in a...

Forecast: Hepatitis C drug market to hit $10 billion in 2013.
May 17, 2004... 2004 MAY 17 - (NewsRx.com & NewsRx.net) -- Decision Resources, Inc., a research and advisory firm focusing on pharmaceutical and healthcare issues, has found the growing number of patients with advanced liver disease will fuel a rise of the...

24-week data presented from Viramidine phase II clinical trials.
May 17, 2004... 2004 MAY 17 - (NewsRx.com & NewsRx.net) -- Valeant Pharmaceuticals (VRX) presented 24-week data from phase II clinical trials of Viramidine, a nucleoside (guanosine) analog Valeant is developing in oral form for the treatment of chronic...

NDA submitted in Japan for Peg-Intron and Rebetol combination therapy.
May 17, 2004... 2004 MAY 17 - (NewsRx.com & NewsRx.net) -- Schering-Plough Corporation (SGP) announced that Schering-Plough K.K., the company's subsidiary in Japan, has submitted a New Drug Application (J-NDA) to the Ministry of Health, Labor and Welfare...

Study explores options for nonresponders to Peg-Intron/Rebetol therapy.
May 17, 2004... 2004 MAY 17 - (NewsRx.com & NewsRx.net) -- A new study seeks to answer one of the most challenging and important questions in hepatitis C therapy today: What is the best option for patients in whom one of the most widely prescribed treatments...

Substance abuse experts call for government backing to prevent hepatitis C.
May 17, 2004... 2004 MAY 17 - (NewsRx.com & NewsRx.net) -- A team of drug researchers from Imperial College London want prevention campaigns supported by stronger government public health policies to help stop the continuing spread of the hepatitis C virus...

Risk factors for hepatitis C in Alaska natives reported.
May 17, 2004... 2004 MAY 17 - (NewsRx.com & NewsRx.net) -- Researchers report the epidemiology and risk factors for hepatitis C in Alaska natives in a recent issue of the journal Hepatology. According to scientists in the United States, "Large cohorts of...

Interferon and ribavirin synergize to inhibit intracellular HCV replication.
May 17, 2004... 2004 MAY 17 - (NewsRx.com & NewsRx.net) -- Interferon and ribavirin synergize to inhibit intracellular HCV replication. "Treatment of hepatitis C virus (HCV) infection with interferon (IFN)-alpha and ribavirin combination therapy results in...

Serum levels of HDV RNA help to define liver disease status.
May 17, 2004... 2004 MAY 17 - (NewsRx.com & NewsRx.net) -- Serum levels of HDV RNA help to define liver disease status. "Some hepatitis B virus (HBV) carriers with chronic hepatitis delta virus (HDV) superinfection show progressive chronic hepatitis,...

Hepatitis A/B vaccine cost-effective substitute for hepatitis B vaccine.
May 17, 2004... 2004 MAY 17 - (NewsRx.com & NewsRx.net) -- Substituting the bivalent hepatitis A/B vaccine for the hepatitis B in prisons in the United States would be cost-effective. According to a study from the United States, "Hepatitis B immunization...

Chronic liver disease mortality in the United States reported.
May 17, 2004... 2004 MAY 17 - (NewsRx.com & NewsRx.net) -- Researchers report the prevalence of chronic liver disease mortality in the United States in a recent issue of the journal Hepatology. "In 1998, chronic liver disease (CLD) was the tenth leading...

Global Med prepares for first Sub-Saharan African software installation.
May 17, 2004... 2004 MAY 17 - (NewsRx.com & NewsRx.net) -- Global Med Technologies, Inc., (GLOB) announced the kickoff, in May 2004, of its first sub-Saharan African implementation (with receipt of funds) of its Wyndgate Technologies division's SafeTrace donor...