Hepatitis Weekly articles from March 2004

Hepatitis Weekly archives from March 2004

Lamivudine maintains adriamycin intensity in hepatitis B patients with lymphoma.
March 1, 2004... 2004 MAR 1 - (NewsRx.com & NewsRx.net) -- Lamivudine maintains adriamycin intensity in hepatitis B patients with lymphoma. According to researchers in South Korea, "we investigated the effectiveness of lamivudine to prevent hepatitis flare...

Hepatitis C virus-infected patients with depression tolerate citalopram.
March 1, 2004... 2004 MAR 1 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus-infected patients with depression tolerate citalopram. "Hepatitis C affects an estimated 4 million Americans and 100 million people worldwide. Rates of depression are higher than...

APOE genotypes may influence a person's response to interferon-alpha.
March 1, 2004... 2004 MAR 1 - (NewsRx.com & NewsRx.net) -- APOE genotypes may influence a person's response to interferon-alpha. According to recent research published in the journal Psychosomatics, "neuropsychiatric complications are common in patients...

Genotype 3 increases the risk for steatosis in those infected with hepatitis C.
March 1, 2004... 2004 MAR 1 - (NewsRx.com & NewsRx.net) -- Genotype 3 increases the risk for steatosis in those infected with hepatitis C. According to published research from the United States, "hepatic steatosis is a recognized feature of hepatitis C...

A newly discovered mimotope could lead the way to HCV receptor antagonism.
March 1, 2004... 2004 MAR 1 - (NewsRx.com & NewsRx.net) -- A newly discovered mimotope could lead the way to HCV receptor antagonism. According to a study from the People's Republic of China, "the human CD81 (hCD81), the most recently proposed receptor of...

Brazilian ex-soccer players may have spread hepatitis C with shared needles.
March 1, 2004... 2004 MAR 1 - (NewsRx.com & NewsRx.net) -- Brazilian ex-soccer players may have spread hepatitis C with shared needles. According to recent research from Brazil, "in order to evaluate the significance of injecting vitamins complexes and...

Atorvastatin causes asymptomatic elevations of liver enzyme levels.
March 1, 2004... 2004 MAR 1 - (NewsRx.com & NewsRx.net) -- Atorvastatin causes asymptomatic elevations of liver enzyme levels. "The 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (also known as statins) are associated with elevated transaminase...

Procleix Ultrio Assay clinical trials commence.
March 1, 2004... 2004 MAR 1 - (NewsRx.com & NewsRx.net) -- Chiron Corporation (CHIR) announced that the U.S. clinical trials of the Procleix Ultrio Assay on the Procleix Tigris system have started in San Diego, California, under an investigational new drug. ...

Small molecule drug company files registration statement for IPO.
March 1, 2004... 2004 MAR 1 - (NewsRx.com & NewsRx.net) -- Metabasis Therapeutics, Inc., announced in February 2004 that it has filed a registration statement with the U.S. Securities and Exchange Commission relating to an initial public offering (IPO) of its...

Hydrangeae dulcis folium suppresses liver injury in rats.
March 1, 2004... 2004 MAR 1 - (NewsRx.com & NewsRx.net) -- Hydrangeae dulcis folium suppresses liver injury in rats. "Hydrangeae dulcis folium, the fermented and dried leaves of Hydrangea macrophylla SER. var. thunbergii MAKINO, suppressed...

Ceplene maker reports net loss for first quarter.
March 1, 2004... 2004 MAR 1 - (NewsRx.com & NewsRx.net) -- Maxim Pharmaceuticals, Inc., (MAXM) announced results for the quarter ended December 31, 2003, the first quarter of the company's 2004 fiscal year. The net loss applicable to common stock for the...

Pharmaceutical company announces 2003 financial results.
March 1, 2004... 2004 MAR 1 - (NewsRx.com & NewsRx.net) -- Rigel Pharmaceuticals, Inc., (RIGL) reported financial results for the fourth quarter and year ended December 31, 2003. Rigel reported revenue from collaborations of $2.1 million in the fourth...

HBV treatment can lead to recovery of virus-specific T-cell responses.
March 1, 2004... 2004 MAR 1 - (NewsRx.com & NewsRx.net) -- HBV treatment can lead to the recovery of HBV-specific T-cell responses in HIV patients. "Liver-related mortality is an increasing problem in human immunodeficiency virus (HIV)/hepatitis B virus...

Hepatitis C virus infection raises the risk for oral squamous cell carcinoma.
March 1, 2004... 2004 MAR 1 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus infection raises the risk for oral squamous cell carcinoma. "The most important complication of oral lichen planus (OLP) is the development of oral squamous cell carcinoma (OSCC)...

Phase I study to begin for therapeutic vaccine for hepatitis.
March 1, 2004... 2004 MAR 1 - (NewsRx.com & NewsRx.net) -- Genencor International, Inc., (GCOR) will begin phase I safety and immunogenicity testing for its DNA-based therapeutic vaccine to treat hepatitis B. Trials are scheduled to begin under an...

Cucumber mosaic virus as carrier of a hepatitis C virus-derived epitope.
March 1, 2004... 2004 MAR 1 - (NewsRx.com & NewsRx.net) -- The cucumber mosaic virus can be used as a carrier of a hepatitis C virus-derived epitope. "Cucumber mosaic virus (CMV) is a three component isodiametric plant virus which is common worldwide and...

IL-23 induces strong immune responses in hepatitis C DNA immunization.
March 1, 2004... 2004 MAR 1 - (NewsRx.com & NewsRx.net) -- IL-23 induces stronger sustained CTL and Th1 immune responses than does IL-12 after hepatitis C virus envelope protein 2 DNA immunization. "IL-23 is a heterodimeric cytokine consisting of p19 and...

Highest therapy response rates to date seen in coinfected patients.
March 1, 2004... 2004 MAR 1 - (NewsRx.com & NewsRx.net) -- A Mount Sinai School of Medicine researcher reported results from a study with a drug combination that showed the highest hepatitis C treatment response rates ever reported in patients infected with...

Mild infection will rapidly worsen in one in three people affected.
March 1, 2004... 2004 MAR 1 - (NewsRx.com & NewsRx.net) -- Mild hepatitis C infection will rapidly worsen in one in three of those affected, suggests new research. This is particularly likely in those who are older when first infected, and those who already...

Clinical trials of Procleix Ultrio Assay begin on Procleix Tigris system.
March 1, 2004... 2004 MAR 1 - (NewsRx.com & NewsRx.net) -- Gen-Probe Incorporated (GPRO) announced that clinical trials of the Procleix Ultrio Assay, for the simultaneous detection of human immunodeficiency virus 1 (HIV-1), the virus that causes AIDS, hepatitis...

Exogenous TRAIL introduces liver cells to death and inflammation.
March 1, 2004... 2004 MAR 1 - (NewsRx.com & NewsRx.net) -- Exogenous TRAIL introduces liver cells to death and inflammation. "The TNF-related apoptosis-inducing ligand (TRAIL) induces apoptosis of tumor cells but not most normal cells. Its role in hepatic...

Losing weight, exercising slows progression of chronic liver problems.
March 1, 2004... 2004 MAR 1 - (NewsRx.com & NewsRx.net) -- Losing weight and exercising regularly slows progression of chronic liver disease in those who are overweight, indicates a new study. Being overweight is bad for the liver. And nonalcoholic fatty...

Binding sites keep hepatitis C virus sensitive to non-nucleoside inhibitors.
March 1, 2004... 2004 MAR 1 - (NewsRx.com & NewsRx.net) -- Binding sites keep hepatitis C virus sensitive to non-nucleoside inhibitors. According to published research from the United States, "the RNA-dependent RNA polymerase of hepatitis C virus (HCV) is...

Truncated hepatitis B virus X gene sequences associate with liver cancer.
March 1, 2004... 2004 MAR 1 - (NewsRx.com & NewsRx.net) -- Truncated hepatitis B virus X gene sequences associate with liver cancer. "Although the integration of hepatitis B virus (HBV) into human DNA has been found to be associated with the development of...

The insulin-like growth factor axis encourages liver cancer formation.
March 1, 2004... 2004 MAR 1 - (NewsRx.com & NewsRx.net) -- The insulin-like growth factor axis encourages liver cancer formation. According to recent research published in the journal Hormone and Metabolic Research, "primary hepatocellular carcinoma (HCC)...

The garlic extract allicin defends against hepatotoxicity in vivo.
March 1, 2004... 2004 MAR 1 - (NewsRx.com & NewsRx.net) -- The garlic extract allicin defends against hepatotoxicity in vivo. "Allicin (diallythiosulfinate) is the main biologically active component of freshly crushed garlic (Alliaceae Allium sativum Linn.)...

Histology stabilizes in HCV-recurrent living donor liver transplant recipients.
March 1, 2004... 2004 MAR 1 - (NewsRx.com & NewsRx.net) -- Histology stabilizes in HCV-recurrent living donor liver transplant recipients. "Recurrence of hepatitis C virus (HCV) after liver transplantation (LT) is a universal phenomenon. Recent reports have...

Hepatitis B virus X protein uses HIF-1 alpha to stimulate angiogenesis.
March 1, 2004... 2004 MAR 1 - (NewsRx.com & NewsRx.net) -- Hepatitis B virus X protein uses HIF-1 alpha to stimulate angiogenesis. "Hepatitis B virus X protein (HBx) is closely involved in the development of hepatocellular carcinoma, a highly vascularized...

Aging hepatitis C virus carriers should undergo screenings for liver cancer.
March 8, 2004... 2004 MAR 8 - (NewsRx.com & NewsRx.net) -- Aging hepatitis C virus carriers should undergo screenings for liver cancer. According to published research from Japan, "a mass screening in 1990 of H town in Japan demonstrated a high prevalence...

The LCx HCV RNA quantitative assay possesses several key attributes.
March 8, 2004... 2004 MAR 8 - (NewsRx.com & NewsRx.net) -- The LCx HCV RNA quantitative assay possesses several key attributes. "The LCx HCV RNA quantitative assay (Abbott Laboratories, North Chicago, IL) is designed to use competitive reverse...

Genome-wide scans could identify genes that present a risk for liver fibrosis.
March 8, 2004... 2004 MAR 8 - (NewsRx.com & NewsRx.net) -- Genome-wide scans could identify genes that present a risk for liver fibrosis. According to a study from Germany, "hepatic fibrosis is the result of chronic viral, toxic, autoimmune, or cholestatic...

Viral DNA remains in the chronically infected liver despite viral clearance.
March 8, 2004... 2004 MAR 8 - (NewsRx.com & NewsRx.net) -- Viral DNA remains in the chronically infected liver despite viral clearance. "We determined the frequency of integrated viral DNA in the livers of three woodchucks chronically infected with the...

Swift production of neutralizing antibody halts hepadnavirus infection.
March 8, 2004... 2004 MAR 8 - (NewsRx.com & NewsRx.net) -- Swift production of neutralizing antibody halts hepadnavirus infection. "Hepatitis B virus (HBV) frequently causes transient infections in adults but chronic infections in infants. The basis of...

A new expression vector augments the cloning of full-length HBV genomes.
March 8, 2004... 2004 MAR 8 - (NewsRx.com & NewsRx.net) -- A new expression vector augments the cloning of full-length genomes from patients. According to recent research from the United States, "analyses of drug susceptibility and replication capacity for...

Hepatitis C virus relies on cellular proliferation for genomic replication.
March 8, 2004... 2004 MAR 8 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus relies on cellular proliferation for genomic replication. "Considerable controversy surrounds the impact of hepatitis C virus (HCV) protein expression on viability of host cells...

A fully automated chemiluminescent microparticle immunoassay counts HBV antigen.
March 8, 2004... 2004 MAR 8 - (NewsRx.com & NewsRx.net) -- A fully automated chemiluminescent microparticle immunoassay counts HBV antigen. "A fully automated chemiluminescent microparticle immunoassay (Architect HBsAg QT) was used for the detection and...

Novel compounds reveal an ability to stem hepatitis C virus replication.
March 8, 2004... 2004 MAR 8 - (NewsRx.com & NewsRx.net) -- Novel compounds reveal an ability to stem hepatitis C virus replication. "A novel series of 1-(4-chlorophenyl)-4-hydroxy-1H-pyrazole-3-carboxylic acid hydrazide analogs and some derived...

Peptidyl-alpha-ketoamide inhibitors take unusual steps to block HCV protease.
March 8, 2004... 2004 MAR 8 - (NewsRx.com & NewsRx.net) -- Peptidyl-alpha-ketoamide inhibitors take unusual steps to block HCV protease According to recent research published in the journal Archives of Biochemistry and Biophysics, "a series of novel...

Albuferon maker reports increased net loss in 2003.
March 8, 2004... 2004 MAR 8 - (NewsRx.com & NewsRx.net) -- Human Genome Sciences, Inc., (HGSI) announced financial results for the quarter and full year periods ended December 31, 2003, and provided guidance for financial results anticipated for the full year...

Biotech company reports 2003 and fourth quarter financial results.
March 8, 2004... 2004 MAR 8 - (NewsRx.com & NewsRx.net) -- Genencor International, Inc., (GCOR) reported that for the full year ended December 31, 2003, total revenues increased by 9% to $383.2 million, compared to $350.1 million in 2002. Product revenues...

Helicobacter pylori has been implicated in the formation of liver cancer.
March 8, 2004... 2004 MAR 8 - (NewsRx.com & NewsRx.net) -- Helicobacter pylori has been implicated in the formation of liver cancer. "Helicobacter species can induce carcinoma in the liver of certain mice. Furthermore, Helicobacter pylori (H. pylori)...

A new cis-acting replication element will provide insight into HCV RNA action.
March 8, 2004... 2004 MAR 8 - (NewsRx.com & NewsRx.net) -- A new cis-acting replication element will provide insight into HCV RNA action. "RNA structures play key roles in the replication of RNA viruses. Sequence alignment software, thermodynamic RNA...

VIR201 data presented at conference.
March 8, 2004... 2004 MAR 8 - (NewsRx.com & NewsRx.net) -- Virax Holdings, Ltd., announced that its research partner, the Australian National Centre for HIV Epidemiology and Clinical Research (NCHECR), presented data and released results of the recent clinical...

Nabi signs international distribution agreement for Nabi-HB.
March 8, 2004... 2004 MAR 8 - (NewsRx.com & NewsRx.net) -- Nabi Biopharmaceuticals (NABI) announced that it has signed an international distribution agreement for Nabi-HB [Hepatitis B Immune Globulin (Human)] with Kamada, Ltd., a global biopharmaceutical...

Results reported in landmark study evaluating Ribavirin in HIV/HCV patients.
March 8, 2004... 2004 MAR 8 - (NewsRx.com & NewsRx.net) -- Roche announced that results from the largest study conducted to date evaluating chronic hepatitis C treatment among patients co-infected with HIV and HCV were presented at the 11th annual Conference on...

Vaccine possible for multiple strains of hepatitis C, evidence shows.
March 8, 2004... 2004 MAR 8 - (NewsRx.com & NewsRx.net) -- Studies at the Southwest Foundation for Biomedical Research offer the first evidence that a vaccine against all strains of the hepatitis C virus should be possible, since chimpanzees that have...

Hepatitis E virus DNA vaccine protected cynomolgus macaques against infection.
March 8, 2004... 2004 MAR 8 - (NewsRx.com & NewsRx.net) -- A hepatitis E virus DNA vaccine administered by gene gun protected cynomolgus macaques against infection. According to published research from the United States, "The protective efficacy of a DNA...

Committee approves mandatory hepatitis vaccines for Indiana high schools.
March 8, 2004... 2004 MAR 8 - (NewsRx.com & NewsRx.net) -- A Senate committee approved a bill February 18, 2004, that would require high school students to receive a hepatitis B vaccine. Indiana students currently have to get the hepatitis B vaccine before...

Eleven diagnostic assays approved for hepatitis, PSA, alpha-fetoprotein.
March 8, 2004... 2004 MAR 8 - (NewsRx.com & NewsRx.net) -- Abbott Laboratories (ABT) announced that it has received approval from the U.S. Food and Drug Administration (FDA) for 11 diagnostic assays for hepatitis, prostate specific antigen (PSA), and...

Altered iron associates with mutations in those with chronic hepatitis C.
March 8, 2004... 2004 MAR 8 - (NewsRx.com & NewsRx.net) -- Altered iron stores associate with mutations in those with chronic hepatitis C. According to published research from Germany, "hepatitis C virus infection is often associated with an elevation of...

Denaturing high-performance liquid chromatography can do HCV genotyping.
March 8, 2004... 2004 MAR 8 - (NewsRx.com & NewsRx.net) -- Denaturing high-performance liquid chromatography can do HCV genotyping. According to a study from the United States, "determination of the hepatitis C virus (HCV) genotype for infected patients...

Renal function should dictate ribavirin dose in patients with hepatitis C.
March 15, 2004... 2004 MAR 15 - (NewsRx.com & NewsRx.net) -- Renal function should dictate ribavirin dose in patients with hepatitis C. According to a study from Sweden, "ribavirin in combination with interferon alpha-2 or pegylated interferon is the...

Prechemotherapy HBV DNA marks viral reactivation risk in breast cancer patients.
March 15, 2004... 2004 MAR 15 - (NewsRx.com & NewsRx.net) -- Prechemotherapy HBV DNA marks viral reactivation risk in breast cancer patients. "Hepatitis B virus (HBV) reactivation during cytotoxic chemotherapy for cancer may complicate treatment and cause...

Extrahepatic manifestations abound where hepatic B cell expansion occurs.
March 15, 2004... 2004 MAR 15 - (NewsRx.com & NewsRx.net) -- Extrahepatic manifestations abound where hepatic B cell expansion occurs. "B cell repertoire in three biological compartments (liver, bone marrow and peripheral blood) of 30 unselected patients...

Thymosin-alpha 1 improves interferon-alpha's efficacy against hepatitis C virus.
March 15, 2004... 2004 MAR 15 - (NewsRx.com & NewsRx.net) -- Thymosin-alpha 1 improves interferon-alpha's efficacy against hepatitis C virus. According to a study from Italy, "in this pilot study, we evaluated the efficacy of interferon-alpha (IFN) plus...

High leptin levels associate with fibrosis severity in chronic hepatitis C.
March 15, 2004... 2004 MAR 15 - (NewsRx.com & NewsRx.net) -- High leptin levels associate with fibrosis severity in chronic hepatitis C. According to a study from France, "recent attention has focused on the liver profibrogenic role of leptin in animal...

Adefovir therapy reduces hepatitis B virus load without generating mutants.
March 15, 2004... 2004 MAR 15 - (NewsRx.com & NewsRx.net) -- Adefovir therapy reduces hepatitis B virus load without generating mutants. According to published research from France, "phase II and III clinical trials of adefovir dipivoxil (ADV) for the...

Ciprofloxacin intake generates a case of liver failure.
March 15, 2004... 2004 MAR 15 - (NewsRx.com & NewsRx.net) -- Ciprofloxacin intake generates a case of liver failure. According to a study from Austria, "ciprofloxacin is a fluorinated quinolone antibiotic with relatively low occurrence of adverse side...

FDA clears enhanced bacteria detection device.
March 15, 2004... 2004 MAR 15 - (NewsRx.com & NewsRx.net) -- Pall Corporation (PLL) announced that the U.S. Food and Drug Administration (FDA) granted clearance to market the new Pall eBDS system. The enhanced Bacteria Detection System offers a more...

Transgenic mice show how interferon-alpha rules HCV 5' UTR-directed translation.
March 15, 2004... 2004 MAR 15 - (NewsRx.com & NewsRx.net) -- Transgenic mice show how interferon-alpha rules HCV 5' UTR-directed translation. "The effect of interferon alpha (IFN-alpha) and the progression of the cell cycle on translation mediated by the 5'...

Audit faults U.S. Marshals Service for poor prisoner healthcare.
March 15, 2004... 2004 MAR 15 - (NewsRx.com & NewsRx.net) -- The U.S. Marshals Service does a poor job of providing medical services to thousands of federal prisoners and doesn't adequately track those with contagious diseases such as tuberculosis, according to...

Multiplex polymerase chain reaction identifies hepatitis B virus genotypes.
March 15, 2004... 2004 MAR 15 - (NewsRx.com & NewsRx.net) -- Multiplex polymerase chain reaction identifies hepatitis B virus genotypes A-F. "Eight genotypes (A-H) of hepatitis B virus (HBV) are known with variations in nucleotide sequences greater than 8%....

Maker of protein therapeutics reports nets losses for Q4 and full year.
March 15, 2004... 2004 MAR 15 - (NewsRx.com & NewsRx.net) -- Maxygen, Inc., (MAXY) reported financial results for the fourth quarter and year ended December 31, 2003. For the year ended December 31, 2003, Maxygen reported a non-GAAP (generally accepted...

Hepatitis B vaccine-induced HBV S gene mutants found in Chinese children.
March 15, 2004... 2004 MAR 15 - (NewsRx.com & NewsRx.net) -- Researchers have discovered hepatitis B virus vaccine-induced escape mutants of HBVS gene among children from the Qidong area of China. "Hepatitis B virus (HBV) infection is the main factor that...

Interferon induction provides little benefit to chronic hepatitis C patients.
March 15, 2004... 2004 MAR 15 - (NewsRx.com & NewsRx.net) -- Interferon induction provides little benefit to chronic hepatitis C patients. "Pilot studies have suggested that the addition of amantadine to interferon (IFN) is effective against hepatitis C...

Cross-genotype immunity to hepatitis C virus outlined.
March 15, 2004... 2004 MAR 15 - (NewsRx.com & NewsRx.net) -- Researchers outline cross-genotype immunity to hepatitis C virus in a recent issue of the Journal of Virology. "Recent studies in humans and chimpanzees suggest that immunity can be induced to...

Non-responder patients test HCV RNA negative with Zadaxin triple therapy.
March 15, 2004... 2004 MAR 15 - (NewsRx.com & NewsRx.net) -- SciClone Pharmaceuticals, Inc., (SCLN) reported positive data from a pilot clinical trial in hepatitis C patients who have not responded to previous therapy. Forty-one percent of the non-responder...

Peg-Intron Redipen launched in U.S.
March 15, 2004... 2004 MAR 15 - (NewsRx.com & NewsRx.net) -- Schering-Plough Corporation (SGP) announced the U.S. launch of Peg-Intron Redipen for administering pegylated interferon therapy for chronic hepatitis C. Peg-Intron Redipen is designed to be...

Clinical trial of ANA971 initiated.
March 15, 2004... 2004 MAR 15 - (NewsRx.com & NewsRx.net) -- Anadys Pharmaceuticals, Inc., has initiated a clinical trial of ANA971, an orally administered prodrug of isatoribine. Isatoribine is a nucleoside analog in development for the treatment of...

Non-alcoholic fatty liver disease is due to become a major public health issue.
March 15, 2004... 2004 MAR 15 - (NewsRx.com & NewsRx.net) -- Non-alcoholic fatty liver disease is due to become a major public health issue. "The spectrum of pathological lesions observed in non-alcoholic fatty liver disease (NAFLD) is wide and strongly...

Hepatitis C virus strongly influences the phenotype of CD8+ T cells.
March 15, 2004... 2004 MAR 15 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus strongly influences the phenotype of antiviral CD8+ T cells. According to recent research published in the Journal of Immunology, "recent studies using MHC class I tetramers have...

Tubercin testing continues at University of Colorado's Health Science Center.
March 15, 2004... 2004 MAR 15 - (NewsRx.com & NewsRx.net) -- Hard to Treat Diseases, Inc., (HTDS) announced that the University of Colorado's Health Science Center (UCHSC) will continue its testing of Tubercin in conjunction with the Denver Veteran's Affairs...

Subtype mutations of the HCV envelope 2 region don't predict antiviral efficacy.
March 15, 2004... 2004 MAR 15 - (NewsRx.com & NewsRx.net) -- Subtype mutations of the HCV envelope 2 region don't predict antiviral efficacy. "The aim of this study was to determine whether specific sequences of the phosphorylation homology domain (PePHD)...

Healthcare workers in central Italy show a trend towards HCV prevalence.
March 15, 2004... 2004 MAR 15 - (NewsRx.com & NewsRx.net) -- Healthcare workers in central Italy show a trend towards HCV prevalence. "Healthcare workers are at risk of acquiring transmissible diseases. Controversial results have been reported about HCV. The...

Hepatitis C virus core proteins work apart from p53 to regulate cell growth.
March 15, 2004... 2004 MAR 15 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus core proteins work apart from p53 to regulate cell growth. "Several reports have shown that activity and/or expression of p53 can be modulated by hepatitis C virus (HCV) proteins...

Patent granted for Epitope-based vaccines targeting hepatitis B virus.
March 15, 2004... 2004 MAR 15 - (NewsRx.com & NewsRx.net) -- Epimmune, Inc., (EPMN) announced the issuance of U.S. Patent No. 6,689,363, directed to compositions and methods of using antigen fragments, or epitopes, to induce cellular, or T cell, immune responses...

Engineered cells monitor hepatitis C virus replication and drug response.
March 15, 2004... 2004 MAR 15 - (NewsRx.com & NewsRx.net) -- Engineered cells monitor hepatitis C virus replication and drug response. "Hepatitis C virus (HCV) encodes a polyprotein that needs to be processed proteolytically by cellular and viral proteases...

Laser capture microdissection quantifies HCV core protein in single cells.
March 15, 2004... 2004 MAR 15 - (NewsRx.com & NewsRx.net) -- Laser capture microdissection quantifies HCV core protein in single cells. According to published research from Italy, "immunohistochemistry provides valuable information concerning the...

Acute renal tubular injury may be a complication of acute hepatitis A infection.
March 15, 2004... 2004 MAR 15 - (NewsRx.com & NewsRx.net) -- Acute renal tubular injury may be a complication of acute hepatitis A infection. "Acute renal failure has rarely been reported in association with acute hepatitis A infection. The commonest form of...

Marmosets infected with GB virus B are a surrogate model for HCV infection.
March 22, 2004... 2004 MAR 22 - (NewsRx.com & NewsRx.net) -- Marmosets infected with GB virus B are a surrogate model for HCV infection. "GB virus B (GBV-B), a flavivirus closely related to HCV, has previously been shown to infect and replicate to high...

Patients with hepatitis B virus genotype C experience delayed seroconversion.
March 22, 2004... 2004 MAR 22 - (NewsRx.com & NewsRx.net) -- Patients with hepatitis B virus genotype C experience delayed seroconversion. According to a study from Taiwan, "hepatitis B virus (HBV) is classified into eight genotypes (A-H), and genotype C is...

Extended periods of undetectable HBV DNA bode well for nonrelapse after therapy.
March 22, 2004... 2004 MAR 22 - (NewsRx.com & NewsRx.net) -- Extended periods of undetectable HBV DNA bode well for nonrelapse after therapy. According to recent research from Japan, "there have been reports of relapse after cessation of lamivudine...

Mimotopes could be valuable for diagnosing hepatitis C virus infection.
March 22, 2004... 2004 MAR 22 - (NewsRx.com & NewsRx.net) -- Mimotopes could be valuable for diagnosing hepatitis C virus infection. "The hepatitis C virus (HCV) nonstructural 3 (NS3) protein is composed of an amino terminal protease and a carboxyl terminal...

Hepatitis B virus X protein makes mice more susceptible to carcinogens.
March 22, 2004... 2004 MAR 22 - (NewsRx.com & NewsRx.net) -- Hepatitis B virus X protein makes mice more susceptible to carcinogens. "The hepatitis B virus X (HBx) protein is thought to be implicated in the development of human hepatocellular carcinoma...