Hepatitis Weekly articles from March 2003

Hepatitis Weekly archives from March 2003

Thrombosis associates with advanced fibrosis in hepatitis patients.
March 3, 2003... 2003 MAR 3 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Medical researchers in Greece have advised that patients infected with hepatitis B or C viruses stand a greater risk for developing advanced liver fibrosis when...

Epidermal powder immunization a safe and effective vaccination method.
March 3, 2003... 2003 MAR 3 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Researchers at PowderJet Vaccines, Inc., have announced that hepatitis B virus (HBV) antigen can be delivered as a powdered formulation to the skin and generate...

Preneoplastic cells show relevance to risk for human liver cancer.
March 3, 2003... 2003 MAR 3 - (NewsRx.com & NewsRx.net) -- Performing liver biopsies to check for preneoplastic lesions affords physicians a useful way to assess the risk for liver cancer in patients with diseases such as chronic viral hepatitis, researchers in...

Cell cycle-regulated gene HURP is overexpressed in hepatocellular carcinoma.
March 3, 2003... 2003 MAR 3 - (NewsRx.com & NewsRx.net) -- The newly identified gene for hepatoma upregulated protein (HURP), which regulates the cell cycle, is overexpressed in hepatocellular carcinoma, researchers in Taiwan report. "An analytic strategy...

TRAIL has potential use for treating infectious disease and cancer.
March 3, 2003... 2003 MAR 3 - (NewsRx.com & NewsRx.net) -- "Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is able to kill a broad spectrum of tumor cells but appears to be nontoxic to most normal cells. Because there are conflicting data about...

Small interfering RNAs clear replicating hepatitis C virus in cell culture.
March 3, 2003... 2003 MAR 3 - (NewsRx.com & NewsRx.net) -- Silencing RNAs offer a way to diminish hepatitis C virus RNA expression, according to researchers in the United States. "RNA interference is a cellular process of gene silencing in which small...

Growth hormone binding protein eliminates injury to liver cells.
March 3, 2003... 2003 MAR 3 - (NewsRx.com & NewsRx.net) -- According to a study from the United States, "acute liver failure caused by viral hepatitis or toxic damage involves both apoptotic and necrotic pathways. Insulin-like growth factor (IGF) binding...

IL-2 increases CD4+ numbers but does not enhance responses to immunization.
March 3, 2003... 2003 MAR 3 - (NewsRx.com & NewsRx.net) -- According to recent research from the United States, "To ascertain whether CD4+ lymphocyte increases induced by interleukin (IL)-2 enhanced in vivo immune responses, 38 human immunodeficiency virus...

Furin linked to the maturation of hepatitis B antigen.
March 3, 2003... 2003 MAR 3 - (NewsRx.com & NewsRx.net) -- Medical investigators have suggested that furin may be associated with the maturation of the hepatitis B e antigen. According to a study from France, "the hepatitis B virus P22 protein is a...

Medical injections still a source of acute hepatitis B in Poland.
March 3, 2003... 2003 MAR 3 - (NewsRx.com & NewsRx.net) -- According to new research from Poland, "The aim of this study was to evaluate the role of medically linked risk factors for acute HBV infection in the Podlasie region of North-Eastern Poland." "The...

Novel PCR method developed for detection of extrahepatic hepatitis C replication.
March 3, 2003... 2003 MAR 3 - (NewsRx.com & NewsRx.net) -- "We established a cell culture system for the replication of hepatitis C virus (HCV) by using human T and B leukemia cell lines," researchers in the United States report. "These 2 cell lines were...

Direct sequence analysis of quantitative PCR products yields good results.
March 3, 2003... 2003 MAR 3 - (NewsRx.com & NewsRx.net) -- According to a study from Italy, "hepatitis C virus (HCV) genotyping, combined with quantitative evaluation of HCV RNA, may be beneficial for the management of chronic hepatitis C and in the selection...

Study calls for data allowances in multicenter research of viral infection.
March 3, 2003... 2003 MAR 3 - (NewsRx.com & NewsRx.net) -- According to recent research from England, "to investigate whether it is appropriate to assume comparability of hepatitis virus C (HCV)-RNA results across laboratories in multicenter studies, nine...

Combination of mouse interferons alpha and gamma effective for mouse hepatitis.
March 3, 2003... 2003 MAR 3 - (NewsRx.com & NewsRx.net) -- "Although interferon (IFN)-alpha and IFN-gamma have been reported to exhibit a synergistic antiviral effect through the different signaling pathways in vitro, their therapeutic efficacy is not well...

Pittsburgh company settles suit over hepatitis C drug.
March 3, 2003... 2003 MAR 3 - (NewsRx.com & NewsRx.net) -- Generic drug maker Three Rivers Pharmaceuticals says it has settled a patent battle over a hepatitis C drug with Schering-Plough Corp. As part of the settlement, Kenilworth, New Jersey-based...

Nitric oxide levels rise in livers of people infected with hepatitis C virus.
March 3, 2003... 2003 MAR 3 - (NewsRx.com & NewsRx.net) -- According to recent research from Egypt, "nitric oxide (NO), a recently discovered free radical, is overproduced in liver cirrhosis. Hepatitis C virus (HCV) might increase NO levels via increased...

Cytokine imbalance may influence liver disease and response to therapy.
March 3, 2003... 2003 MAR 3 - (NewsRx.com & NewsRx.net) -- "The liver plays an important physiological role in lipopolysaccharide (LPS) detoxification and, in particular, hepatocytes are involved in the clearance of endotoxin of intestinal derivation. In...

Shunt migration following liver implantation doesn't affect outcomes.
March 3, 2003... 2003 MAR 3 - (NewsRx.com & NewsRx.net) -- According to recent research from the United States, "transjugular intrahepatic portosystemic shunt (TIPS) is a useful procedure for patients with variceal bleeding and refractory ascites. Migration of...

Immune mechanisms supplant hepatitis C virus as a cause of myositis.
March 3, 2003... 2003 MAR 3 - (NewsRx.com & NewsRx.net) -- "We report a case of myositis associated with chronic hepatitis C virus infection. Muscle biopsy and immunohistochemistry showed perifascicular atrophy, few necrotic and regenerating fibres, scarce...

Hospital transmissions responsible for new hepatitis G infections.
March 3, 2003... 2003 MAR 3 - (NewsRx.com & NewsRx.net) -- Epidemiologists have listed nosocomial transmission as a major source of GB virus C (GBV-C) infections, also known as hepatitis G virus, among hospital patients in France. According to a French...

Hepatitis C virus RNA detected in nerve tissues of some patients.
March 3, 2003... 2003 MAR 3 - (NewsRx.com & NewsRx.net) -- Scientists in Italy say they have detected hepatitis C virus (HCV) RNA in the nerve tissues of some HCV-infected patients. "To assess the presence of viral ribonucleic acid (RNA) in nerve tissues...

Specific hepatitis C virus genotype more common among people with coinfection.
March 3, 2003... 2003 MAR 3 - (NewsRx.com & NewsRx.net) -- People coinfected with SEN virus and hepatitis C virus (HCV) may be more likely to be infected with HCV genotype 2a, according to researchers in Taiwan. "To clarify the influence that a recently...

Immune response cells within the liver constrain hepatitis C virus load.
March 10, 2003... 2003 MAR 10 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - New research indicates cytotoxic T lymphocytes (CTLs) localized within the liver are responsible for limiting viral replication in patients infected with...

Switching to intramuscular hepatitis B immune globulin is safe, effective.
March 10, 2003... 2003 MAR 10 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Recurrent hepatitis B virus (HBV) infections can be prevented after liver transplantation with intramuscular injections of hepatitis B immune globulin,...

Hepatitis C virus can infect and replicate in B cell lymphoma cell lines.
March 10, 2003... 2003 MAR 10 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus can infect and replicate in B cell lymphoma cell lines. According to recent research from the United States, "hepatitis C virus (HCV) is a major cause of chronic hepatitis, liver...

Hepatitis C therapy makes long-term remission possible after transplantation.
March 10, 2003... 2003 MAR 10 - (NewsRx.com & NewsRx.net) -- Hepatitis C therapy makes long-term remission possible after kidney transplantation. According to recent research from the United States, "hepatitis C virus infection (HCV) is common in patients...

Psychiatric follow-up may improve hepatitis C virus treatment tolerance.
March 10, 2003... 2003 MAR 10 - (NewsRx.com & NewsRx.net) -- Psychiatric follow-up evaluations may improve treatment tolerance in patients infected with hepatitis C virus. According to a study from France, "hepatitis C represents a major public health...

Retinoic acid enhances the antiviral effect of interferon on hepatitis C virus.
March 10, 2003... 2003 MAR 10 - (NewsRx.com & NewsRx.net) -- Retinoic acid enhances the antiviral effect of interferon on hepatitis C virus. According to a study from Japan, "the concentration of type I interferon receptor (IFN-Rc) in the liver is a crucial...

Transgenic tobacco plants carry gene for hepatitis B virus surface antigen.
March 10, 2003... 2003 MAR 10 - (NewsRx.com & NewsRx.net) -- Transgenic tobacco plants can carry the gene for hepatitis B virus surface antigen. According to recent research from Russia, "the plasmids carrying the gene encoding the hepatitis B surface...

CpG 7909 is active in immunocompromised patients.
March 10, 2003... 2003 MAR 10 - (NewsRx.com & NewsRx.net) -- Coley Pharmaceutical Group, Inc., announced preliminary results from a physician-sponsored human clinical study. Results from the proof-of-principle study demonstrate that Coley's CpG 7909, when...

Interferon treatment in chronic hepatitis C modulates thyroid autoimmunity.
March 10, 2003... 2003 MAR 10 - (NewsRx.com & NewsRx.net) -- Interferon treatment in chronic hepatitis C modulates thyroid autoimmunity. According to a study from Italy, "interferon-alpha (IFN-alpha) treatment for chronic hepatitis C (CHC) has been...

Propafenone is hepatotoxic to some patients.
March 10, 2003... 2003 MAR 10 - (NewsRx.com & NewsRx.net) -- Propafenone is hepatotoxic to some patients. According to recent research from Argentina, "two patients developed acute cholestatic hepatitis during treatment with propafenone. Viral infections,...

Soluble guanylate cyclase modulation is altered by nitric oxide.
March 10, 2003... 2003 MAR 10 - (NewsRx.com & NewsRx.net) -- Soluble guanylate cyclase modulation is altered by nitric oxide in patients with liver disease. According to recent research from Spain, "the glutamate-nitric oxide-cGMP pathway is impaired in...

Surgeons put themselves at risk, despite evidence.
March 10, 2003... 2003 MAR 10 - (NewsRx.com & NewsRx.net) -- Exposure to blood and body fluids while operating places surgeons at risk, yet a large number of doctors continue to put themselves in danger despite knowing the evidence, according to a University of...

Arenaviruses cause incipient liver regeneration in acutely infected primates.
March 10, 2003... 2003 MAR 10 - (NewsRx.com & NewsRx.net) -- Arenaviruses cause incipient liver regeneration in acutely infected rhesus macaques. "Lymphocytic choriomeningitis virus (LCMV) and Lassa virus can cause hemorrhagic fever and liver disease in...

Duck hepatitis B virus subnuclear bodies associate with RNA processing.
March 10, 2003... 2003 MAR 10 - (NewsRx.com & NewsRx.net) -- Duck hepatitis B virus subnuclear bodies associate with RNA processing. "We have reinvestigated the subcellular distribution of the duck hepatitis B virus (DHBV) core protein in infected duck...

Immune response to hepatitis C infection may be higher after renal transplant.
March 17, 2003... 2003 MAR 17 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Immune response to hepatitis C virus (HCV), rather than the activity of the virus itself, may be responsible for de novo glomerulopathy in patients who receive...

Genetic mapping is useful for determining the origin of liver tumors.
March 17, 2003... 2003 MAR 17 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - DNA fingerprinting may offer the best way to determine the clonality of tumors in patients with several hepatocellular carcinoma (HCC) lesions. HCC is a...

Antigens in hepatitis C assays should reflect regional infections.
March 17, 2003... 2003 MAR 17 - (NewsRx.com & NewsRx.net) -- Antigens in hepatitis C assays should reflect regional infections. According to recent research from Thailand, "nonstructural 3 (NS3) protein of hepatitis C virus (HCV) is one of the antigens...

A novel screening assay can detect HCVNS3 serine protease inhibitors.
March 17, 2003... 2003 MAR 17 - (NewsRx.com & NewsRx.net) -- A novel screening assay can detect hepatitis C virus HCVNS3 serine protease inhibitors. "Hepatitis C virus (HCV) infection is a major worldwide health problem, causing chronic hepatitis, liver...

Plasmid DNA encoding for hepatitis B virus (HBV) produces response in mice.
March 17, 2003... 2003 MAR 17 - (NewsRx.com & NewsRx.net) -- Plasmid DNA encoding for hepatitis B virus (HBV) produces an immune response in mice. According to a study from Japan, "Hepatitis B virus (HBV) infection is highly specific to primates. To cross...

Suspected nonalcoholic fatty liver disease calls for liver biopsy.
March 17, 2003... 2003 MAR 17 - (NewsRx.com & NewsRx.net) -- Suspected nonalcoholic fatty liver disease calls for liver biopsy. According to recent research from Canada, "nonalcoholic fatty liver disease (NAFLD) is a common diagnosis among patients referred...

Maximum likelihood testing improves forensic, epidemiologic analysis.
March 17, 2003... 2003 MAR 17 - (NewsRx.com & NewsRx.net) -- Maximum likelihood testing improves forensic and epidemiologic outbreak analysis. "Molecular phylogenetic analyses are frequently used in epidemiologic testing, although only occasionally in...

The progression of hepatitis C infection in children may advance with time.
March 17, 2003... 2003 MAR 17 - (NewsRx.com & NewsRx.net) -- The progression of hepatitis C infection in children may advance with time. According to a study from Italy, "the characteristics and evolution of hepatitis C virus (HCV) infection were...

Kunjin replicon is effective vector for protein delivery.
March 17, 2003... 2003 MAR 17 - (NewsRx.com & NewsRx.net) -- The Kunjin replicon was found to be an effective vector for protein delivery. "The Kunjin replicon was used to express a polytope that consisted of seven hepatitis C virus cytotoxic T lymphocyte...

Females with hepatocellular carcinoma live longer than their male counterparts.
March 24, 2003... 2003 MAR 24 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Disparities in patient follow-up may be one reason that women diagnosed with hepatocellular carcinoma have longer survival than men do. Hepatocellular...

Clinical and ethnic differences predict whether living donors come forward.
March 24, 2003... 2003 MAR 24 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - The clinical nature of a person's liver illness as well as ethnicity may predict whether or not a living donor will volunteer a partial liver donation to that...

An insect larvae system could be used for hepatitis E culture.
March 24, 2003... 2003 MAR 24 - (NewsRx.com & NewsRx.net) -- An insect larvae system could be used for hepatitis E culture. "We report here the expression and purification of a truncated form of the hepatitis E virus ORF2 protein (ORF2Delta111/DeltaTM), from...

Hepatitis C virus antigens may save liver cells from apoptosis.
March 24, 2003... 2003 MAR 24 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus antigens may save liver cells from apoptosis. "Hepatitis C virus (HCV) infection has a strong tendency to evolve to chronicity despite up-regulation of proapoptotic cytokines in...

The MELD score correlates with post-transplant mortality in liver recipients.
March 24, 2003... 2003 MAR 24 - (NewsRx.com & NewsRx.net) -- The MELD score correlates with mortality in liver transplant recipients. "The Model for End-Stage Liver Disease (MELD) score is now the criteria for allocation in liver transplantation for patients...

Higher doses of interferon may overcome nonresponse in chronic hepatitis C.
March 24, 2003... 2003 MAR 24 - (NewsRx.com & NewsRx.net) -- Higher doses of interferon may overcome nonresponse to therapy in chronic hepatitis C. "A large proportion of patients fails to respond to treatment for hepatitis C. Initiation of interferon...

Nucleoside inhibitors reduce skeletal muscle DNA more than adefovir does.
March 24, 2003... 2003 MAR 24 - (NewsRx.com & NewsRx.net) -- Nucleoside inhibitors reduce skeletal muscle cell mitochondrial DNA more than adefovir does. According to a study from the United States, "adefovir is a potent nucleotide analog inhibitor of...

Multiple exposures to certain viruses may lead to autoimmunity.
March 24, 2003... 2003 MAR 24 - (NewsRx.com & NewsRx.net) -- Multiple exposures to certain viruses may lead to autoimmunity. According to recent research from England, "cytochrome P4502D6 (CYP2D6), target of liver kidney microsomal autoantibody type 1...

Daily doses of consensus interferon are not well-tolerated by hepatitis patients.
March 24, 2003... 2003 MAR 24 - (NewsRx.com & NewsRx.net) -- Daily doses of consensus interferon are not well-tolerated by hepatitis patients. "The treatment of chronic hepatitis C patients was enhanced when the combination of interferon alfa-2b and...

Intestinal flora modulates the pathogenesis of non-alcoholic steatohepatitis.
March 24, 2003... 2003 MAR 24 - (NewsRx.com & NewsRx.net) -- Intestinal flora modulates the pathogenesis of non-alcoholic steatohepatitis. "Ob/ob mice, a model for nonalcoholic fatty liver disease (NAFLD), develop intestinal bacterial overgrowth and...

A mutated strain of hepatitis B virus requires wild-type virus to proliferate.
March 24, 2003... 2003 MAR 24 - (NewsRx.com & NewsRx.net) -- A mutated strain of hepatitis B virus requires wild-type virus to proliferate. "A liver transplant recipient reinfected with a lamivudine-resistant mixed wild-type/pre-S1-deleted hepatitis B virus...

Immunization after virus suppression controls chronic hepatitis B.
March 24, 2003... 2003 MAR 24 - (NewsRx.com & NewsRx.net) -- In vivo immunization following virus suppression is a novel approach for inducing immune control in chronic hepatitis B. According to a study from The Netherlands, "Antiviral treatment of patients...

Treatment reduces signs of disease progression in patients with chronic disease.
March 24, 2003... 2003 MAR 24 - (NewsRx.com & NewsRx.net) -- Gilead Sciences (GILD) has announced the publication of results from two studies evaluating the safety and efficacy of Hepsera (adefovir dipivoxil 10 mg), Gilead's once-daily oral antiviral for the...

Viral response to peginterferon is different from that of standard interferon.
March 24, 2003... 2003 MAR 24 - (NewsRx.com & NewsRx.net) -- Viral response to peginterferon is different from that of standard interferon. "Even with pegylated (PEG) interferons (IFN), therapy of chronic hepatitis C (genotype 1) remains unsatisfactory. The...

Class I peptide tetramers characterize viral escape and T cell exhaustion.
March 24, 2003... 2003 MAR 24 - (NewsRx.com & NewsRx.net) -- Class I peptide tetramers characterize viral escape and T cell exhaustion. "Hepatitis C virus (HCV) has infected over 170 million people world wide, and in the majority sets up a chronic infection...

Viral and endogenous processes are responsible for hepatocellular carcinoma.
March 24, 2003... 2003 MAR 24 - (NewsRx.com & NewsRx.net) -- Viral and endogenous processes are responsible for hepatocellular carcinoma. According to recent research from the United States, "primary hepatocellular carcinoma (HCC) is one of the most common...

Growth factor receptor agonists may preserve liver function in liver disorders.
March 24, 2003... 2003 MAR 24 - (NewsRx.com & NewsRx.net) -- Growth factor receptor agonists may preserve liver function in certain liver disorders. According to recent research from the United States, "the vascular endothelium was once thought to function...

Some tattoo, piercing shops still unsafe.
March 24, 2003... 2003 MAR 24 - (NewsRx.com & NewsRx.net) -- A new study of tattooing and body piercing finds that many operators may be putting clients at risk of HIV and hepatitis B and C infection. The study was limited to Australian establishments and...

Workforce focused on key research and development programs.
March 24, 2003... 2003 MAR 24 - (NewsRx.com & NewsRx.net) -- Genelabs Technologies, Inc., (GNLB) announced that it is reducing its workforce by approximately 20%, or 20 employees. The company is not making any reductions to its drug development staff...

Genotype, enzyme levels, and viral load are clues to hepatitis C virus outcomes.
March 31, 2003... 2003 MAR 31 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Medical researchers in Germany have announced that viral genotype and load, as well as liver enzyme levels, are predictors for treatment outcomes in chronic...

Hepatitis B infection has no impact on hepatitis C response to interferon.
March 31, 2003... 2003 MAR 31 - (NewsRx.com & NewsRx.net) -- by Sonia Nichols, senior medical writer - Patients with chronic hepatitis C who carry antibodies to hepatitis B virus core antigen are not likely to show a diminished response to interferon based...

Coinfecting viruses don't change the kinetics of acute HBV infection.
March 31, 2003... 2003 MAR 31 - (NewsRx.com & NewsRx.net) -- Coinfecting viruses don't change the kinetics of acute HBV infection. "The kinetics of hepatitis B virus (HBV) and its surface antigen (HBsAg) during acute hepatitis has not yet been studied...

Alternate pathways regulate the life cycle of hepatitis B virus.
March 31, 2003... 2003 MAR 31 - (NewsRx.com & NewsRx.net) -- Alternate pathways regulate the life cycle of hepatitis B virus. "Hepatitis B virus (HBV) infects humans and certain nonhuman primates. Viral clearance and acute disease are associated with a...

Herpes simplex viruses would be useful for exploring hepatitis C NS5A protein.
March 31, 2003... 2003 MAR 31 - (NewsRx.com & NewsRx.net) -- Herpes simplex viruses would be useful for exploring hepatitis C NS5A protein. According to recent research from Greece, "two herpes simplex type 1 (HSV-1) recombinant viruses carrying the...

Evolution of hepatitis C virus in blood donors differs from that of recipients.
March 31, 2003... 2003 MAR 31 - (NewsRx.com & NewsRx.net) -- The evolution of hepatitis C virus in blood donors differs from that of recipients. "This paper describes the study of hepatitis C virus (HCV) evolution in the largest cohort of HCV-infected blood...

Impaired growth factor signals increase susceptibility to autoimmune hepatitis.
March 31, 2003... 2003 MAR 31 - (NewsRx.com & NewsRx.net) -- Impaired growth factor signals increase murine susceptibility to autoimmune hepatitis. "In autoimmune hepatitis, strong transforming growth factor (TGF)-beta1 expression is found in the inflamed...

Hepatitis C virus NS2 protein inhibits cellular and hepatitis B gene expression.
March 31, 2003... 2003 MAR 31 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus NS2 protein inhibits cellular and hepatitis B gene expression. "The mechanisms leading to viral persistence and hepatocarcinogenesis in hepatitis C virus (HCV) infection are not...

A new polyherbal formula downregulates hepatitis B surface antigen expression.
March 31, 2003... 2003 MAR 31 - (NewsRx.com & NewsRx.net) -- A new polyherbal formula downregulates hepatitis B surface antigen expression. According to recent research from India, "hepatitis B virus is associated with chronic or acute liver diseases and...

Drug use and blood products transmit hepatitis C virus infections in Uzbekistan.
March 31, 2003... 2003 MAR 31 - (NewsRx.com & NewsRx.net) -- Intravenous drug use and blood products transmit hepatitis C virus infections in Uzbekistan. According to a study from Japan, "the aim of this study was to identify hepatitis C virus (HCV)...

Hepatitis B virus genotype D does not influence chronicity in India.
March 31, 2003... 2003 MAR 31 - (NewsRx.com & NewsRx.net) -- Hepatitis B virus genotype D does not influence chronicity in India. According to a study from India, "to determine hepatitis B virus genotype and subtype distribution among HBV infected...

Protein exchanges with hepatitis A virus cover different mechanisms.
March 31, 2003... 2003 MAR 31 - (NewsRx.com & NewsRx.net) -- Protein exchanges with hepatitis A virus cover different mechanisms. "Proteins interacting with RNA structures at the 3' non-translated region (3'NTR) of picornaviruses are probably important...

The nuclear receptors HNF4 alpha and COUP-TF1 regulate HBV genes differently.
March 31, 2003... 2003 MAR 31 - (NewsRx.com & NewsRx.net) -- The nuclear receptors HNF4 alpha and COUP-TF1 regulate HBV genes differently. "To study the effects of the nuclear receptors (NRs) HNF4alpha and COUP-TF1 on the life cycle of hepatitis B virus...

The Versant HCV RNA qualitative assay is called reliable in multicenter study.
March 31, 2003... 2003 MAR 31 - (NewsRx.com & NewsRx.net) -- The Versant HCV RNA qualitative assay is called reliable in a multicenter study. "We report the results of a multicenter evaluation of a new assay for the detection of hepatitis C virus (HCV) RNA...

Pregnant women in Cameroon and Europe have similar HCV infection rates.
March 31, 2003... 2003 MAR 31 - (NewsRx.com & NewsRx.net) -- Pregnant women in Cameroon and Europe have similar HCV infection rates. According to a study from Cameroon, "central Africa is considered to be an area of high endemic hepatitis C infection. To...

Significant hepatitis C interactions may occur in nonaqueous environments.
March 31, 2003... 2003 MAR 31 - (NewsRx.com & NewsRx.net) -- Significant hepatitis C interactions may occur in nonaqueous environments. According to a study from France, "the first crystal structure of a complex between a hepatitis C virus (HCV) core...

Mannose-binding lectin gene mutations influence hepatitis B outcome.
March 31, 2003... 2003 MAR 31 - (NewsRx.com & NewsRx.net) -- Mutations in the mannose-binding lectin (MBL) gene can influence the outcome of hepatitis B. According to a study from Germany, MBL "is a constituent of the human innate immune system which may...

Minocycline therapy can cause drug-induced hepatitis.
March 31, 2003... 2003 MAR 31 - (NewsRx.com & NewsRx.net) -- Minocycline therapy can cause drug-induced hepatitis. "A 25-year-old woman with no history of liver disease developed liver dysfunction associated with severe jaundice and general malaise...

The TT virus has been detected in children with acute respiratory disease.
March 31, 2003... 2003 MAR 31 - (NewsRx.com & NewsRx.net) -- The TT virus has been detected in the nasal passages of children with acute respiratory disease. "The natural history and pathogenic potential of the recently identified TT virus (TTV) are...