Hepatitis Weekly articles from June 2004

Hepatitis Weekly archives from June 2004

The NH[subscript]2-terminal fragment of glypican-3 marks early liver cancer.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- The NH[subscript]2-terminal fragment of glypican-3 marks early liver cancer. "For detection of hepatocellular carcinoma (HCC) in patients with liver cirrhosis, serum alpha-fetoprotein has been...

Glycomics analysis yields a noninvasive means of tracking liver cirrhosis.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Glycomics analysis yields a noninvasive means of tracking liver cirrhosis. According to researchers in Switzerland, "we applied our 'clinical glycomics' technology, based on DNA sequencer/fragment...

Hepatitis B virus coinfection affects hepatitis C virus replication.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Hepatitis B virus coinfection affects hepatitis C virus replication. "Antibodies against envelope glycoprotein 1 and 2 (anti-E1/E2) have been suggested to influence HCV replication levels. Hepatitis...

Livers could retain activated CD8+ T cells with Kupffer cell interference.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Livers could retain activated CD8+ T cells with Kupffer cell interference. According to published research from the United States, "the immune response to foreign antigens in the liver is often...

Nitric oxide may be linked to interferon-induced depression.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Nitric oxide may be linked to interferon-induced depression. According to recent research published in the International Journal of Neuropsychopharmacology, "it has been postulated that interferon...

Nucleoside analogues and mitochondrial toxicity reviewed.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Scientists review nucleoside analogues and mitochondrial toxicity in a recent issue of Clinical Infectious Diseases. "An evaluation of the U.S. Food and Drug Administration's Adverse Event...

Long-term therapy for chronic hepatitis C resolves hereditary telangiectasia.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Long-term therapy for chronic hepatitis C resolves hereditary telangiectasia. According to recent research from the United States, "hereditary hemorrhagic telangiectasia is a group of autosomal...

Cisplatin-induced apoptosis associated with mitochondrial dysregulation.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Cisplatin-induced apoptosis is associated with mitochondrial dysregulation. "Human hepatoma cell lines undergo apoptosis after treatment with cisplatin (CP), by mechanisms that are not fully...

Murine model of type 2 autoimmune hepatitis developed.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Researchers have developed a murine model of type 2 autoimmune hepatitis. "Autoimmune hepatitis (AIH) is characterized by an immune-mediated injury of the hepatic parenchyma of unknown...

A new rapid molecular assay detects at least four strains of the SEN virus.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- A new rapid molecular assay detects at least four strains of the SEN virus. "SEN viruses (SENV) are newly discovered blood-borne single-stranded circular DNA viruses that may play a role in liver...

Nuclear anomalies in regenerative cirrhotic nodules herald liver cancer.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Nuclear anomalies in regenerative cirrhotic nodules herald liver cancer. According to recent research published in the journal Cancer Genetics and Cytogenetics, "human cirrhosis is considered an...

Utility of isolated hepatic perfusion reviewed.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- The utility of isolated hepatic perfusion (IHP) in cancer patients has been reviewed. "Many liver tumors are not suited for surgical resection, and an increasing number of patients are treated by...

Hepatocyte proliferation enhanced by immobilization on 24 nm-sized gold colloid.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Hepatocyte proliferation is enhanced by immobilization on 24 nm-sized gold colloid. According to published research from China, "Bioartificial liver and hepatocyte transplantation is anticipated to...

Triglycerides are controlling elements in the pathology of metabolic syndrome.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Triglycerides are controlling elements in the pathology of metabolic syndrome. "Epidemiological studies in humans, as well as experimental studies in animal models, have shown an association between...

BioArchive product line generates $2.2M in third quarter.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- ThermoGenesis Corp. (KOOL) announced results for its third quarter of fiscal 2004. Net revenues for the quarter ended March 31, 2004, increased 17% to $3,367,000, compared to $2,886,000 for the...

Biopharma reports Q1 revenues of $0.7 million, net loss of $4.8 million.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Genelabs Technologies, Inc., (GNLB) reported revenues of $0.7 million and a net loss of $4.8 million, or $0.05 per share for the first quarter 2004. This compares to revenues of $0.7 million and a...

Diagnostics company reports increased net revenues and first profit.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- IVAX Diagnostics, Inc., (IVD) reported net revenues for the first quarter of 2004 of $4,732,000, an increase of 6.5% over the $4,444,000 from the same period of the previous year. The net income...

Hepatocellular carcinoma progression associates with down-regulated HNF.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Hepatocellular carcinoma progression associates with down-regulated HNF. "Hepatocyte nuclear factors (HNF) play a critical role in the development of the liver. Their roles during liver...

HIV vaccine trial initiated by U.S. Army based on Therapore technology.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Avant Immunotherapeutics, Inc., (AVAN) announced that the Walter Reed Army Institute of Research (WRAIR) has initiated a phase I clinical trial to assess the safety and immunogenicity of an HIV vaccine...

Aldo-keto reductase family pathway generates HP1 from S-1360.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- The aldo-keto reductase family pathway generates HP1 from S-1360. According to a study published in the journal Chemico-Biological Interactions, "S-1360, a 1,3-diketone derivative, was the first HIV...

HCV therapy with IFN/RBV relatively safe in patients coinfected with HIV and HCV.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- HCV therapy with interferon plus ribovarin is relatively safe in patients coinfected with HIV and HCV. According to a study from the American Foundation for AIDS Research, "Human immunodeficiency...

Phase I/IIa trial of ANA380 in hepatitis patients completed.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Anadys Pharmaceuticals, Inc., (ANDS) and LG Life Sciences, Ltd., (KOSPI:68870) of Seoul, Korea, announced summary results from a completed phase I/IIa, double-blind randomized, placebo-controlled dose...

HLA and cytokine polymorphisms linked to hepatitis B vaccine responses.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- HLA and cytokine gene polymorphisms are independently associated with responses to hepatitis B vaccination. "Variable immune responses to hepatitis B virus (HBV) infection and recombinant HBV...

Diversity of hepatitis B virus in Dutch blood donors reported.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Scientists report the diversity and origin of hepatitis B virus in Dutch blood donors in a recent issue of the Journal of Medical Virology. According to recent research from the Netherlands, "Two...

HBV DNA test should replace HBsAg and/or anti-HBc for blood donor screening.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- The hepatitis B virus DNA test should replace HBsAg and/or anti-HBc for blood donor screening. "Prevention of transfusion-transmitted hepatitis B virus (HBV) has historically relied on serological...

Phase II clinical trial of daily Infergen plus Actimmune begins.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- InterMune, Inc., (ITMN) has initiated a phase II clinical trial of the combination of Infergen (interferon alfacon-1) and Actimmune (interferon gamma-1b) for the treatment of patients chronically...

Cells with fully genomic hepatitis C virus display CDK-Rb-E2F signals.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Cells with fully genomic hepatitis C virus display CDK-Rb-E2F signals. According to published research from Japan, "hepatitis C virus (HCV) causes persistent infection in hepatocytes, and this...

5'-Methylthioadenosine modulates inflammatory response to hepatocyte endotoxin.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- 5'-Methylthioadenosine modulates the inflammatory response to hepatocyte endotoxin. "5'-Methylthioadenosine (MTA) is a nucleoside generated from S-adenosylmethionine (AdoMet) during polyamine...

CyA C2 predicts total cholesterol in immunosuppressed kidney transplant patients.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Cyclosporin C2 predicts total cholesterol in immunosuppressed kidney transplant patients. "The aim of this study was to assess the relationship between cyclosporine (CyA) trough level (CO) and...

FTY720 may increase efficacy and tolerability of immunosuppressive regimens.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- FTY720 may increase the efficacy and tolerability of immunosuppressive regimens. According to a study from Ohio State University, "FTY720, a sphingosine 1-phosphate receptor (S1P-R) agonist, is the...

Successful kidney transplants increase with cyclosporine experience.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Successful kidney transplants increase with greater cyclosporine experience. "Following the introduction of cyclosporine as basic immunosuppression in our national transplant program in 1983, the...

Maryland hospital faces congressional review.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- A lack of communication between laboratory inspection agencies, whistle blowers who were ignored, and possible equipment problems were to blame for bad HIV and hepatitis test results at Maryland General...

Microsphere chemoembolization shows promise.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Starch microspheres demonstrated powerful antitumor activity in a murine model of liver cancer. In a recent study from Germany, an "orthotopic, isogenic rat model was used to determine the...

The evolution of hepatocellular carcinoma metastasis is multifaceted.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- The evolution of hepatocellular carcinoma metastasis is multifaceted. According to a study from the Peoples Republic of China, "metastasis remains one of the major challenges before hepatocellular...

Diazoxide boosts programmed cell death in human hepatoma cells.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Diazoxide boosts programmed cell death in human hepatoma cells. According to recent research published in the journal Archives of Pharmacal Research, "the effect of diazoxide, a K+ channel opener,...

J-tipped guidewire suitable for subclavian artery puncture in RPCS placement.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- A J-tipped guidewire is suitable for use in subclavian artery puncture for reservoir port and catheter system (RPCS) placement. Researchers in Japan conducted a study to "verify the feasibility of...

Hepatitis C virus-infected patients say physician interactions fall short.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus-infected patients say physician interactions fall short. "We examined the prevalence and nature of perceived problems in the interaction between physicians and patients diagnosed...

Hepatitis B virus-X protein stimulates mitochondrial dysfunction.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Hepatitis B virus-X protein stimulates mitochondrial dysfunction. "The hepatitis B virus-X protein (HBx) regulates fundamental aspects of mitochondrial physiology. We show that HBx down-regulates...

Secoisolariciresinol and isotaxiresinol block liver cell suicide in mice.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Secoisolariciresinol and isotaxiresinol block liver cell suicide in mice. According to recent research from Japan, "the effects of secoisolariciresinol (1) and isotaxiresinol (2), two major lignans...

Behavioral professionals are key players on chronic hepatitis C treatment teams.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Behavioral clinicians are key players on chronic hepatitis C treatment teams. "Chronic infection with the hepatitis C virus is a major public health concern in the United States and worldwide, and...

Endodermal progenitors differentiate into hepatic and pancreatic lineages.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Endodermal progenitors differentiate into hepatic and pancreatic lineages. According to researchers in Japan, "Experimental injury is useful to induce tissue stem cells, which may exist in small...

Anticoagulant for thromboembolic disorders effective in animal models.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- TransTech Pharma Inc. announced the successful completion of phase I clinical testing of its first drug candidate, TTP889, an orally bioavailable selective inhibitor of the intrinsic coagulation pathway...

Hepatitis C virus core protein has three means of modulating p53 activity.
June 7, 2004... 2004 JUN 7 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus core protein has three means of modulating p53 activity. "Oncogenic virus proteins often target tumor suppressor p53 during virus life cycle. In the case of hepatitis C virus (HCV)...

Diagnoses of zone 3 hepatitis-related autoimmune hepatitis avert cirrhosis.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Diagnoses of zone 3 hepatitis-related autoimmune hepatitis avert cirrhosis. "Autoimmune hepatitis (AIH) is usually a chronic portal-based hepatitis with prominent plasma cells. Although...

Hemofiltration may trap and destroy hepatitis C virus particles.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Hemofiltration may trap and destroy hepatitis C virus particles. "Low incidence rates of hepatocellular carcinoma and cirrhosis in HCV-antibody-positive patients on chronic hemodialysis are...

Liquid chromatography-tandem mass spectrometry measures PMEA in human sera.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Liquid chromatography-tandem mass spectrometry measures PMEA in human sera. "An ultra sensitive method for the direct measurement of 9-(2-phosphonylmethoxyethyl)adenine (PMEA), an antiviral agent...

Interactions between HCV NS5A protein and 2-tAS counteract interferon.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Interactions between HCV NS5A protein and 2-tAS counteract interferon. According to recent research from Japan, "the non-structural protein 5A (NS5A) of hepatitis C virus (HCV) has been implicated...

Hepatitis E virus causes non-A, non-B, non-C acute hepatitis in Japan.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Hepatitis E virus causes non-A, non-B, non-C acute hepatitis in Japan. "Recent studies indicate that hepatitis E virus (HEV) infection occurs not only in developing countries but also in...

Increased vascular HO-1 expression contributes to vasodilation in cirrhotic rats.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Increased vascular heme oxygenase-1 expression contributes to vasodilation in cirrhotic rats. "Vascular heme oxygenase (HO) regulates vascular tone in normal conditions and in some pathologic...

Cleaved form of MAGE-A4 binds to Miz-1 and induces apoptosis in human cells.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- A cleaved form of MAGE-A4 binds to Miz-1 and induces apoptosis in human cells. According to a study from Japan, "Gankyrin, a recently discovered oncoprotein, is a promising target for drug therapy...

New company launched for development of therapeutic DNA vaccines.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- PowderMed Ltd, a new company focusing on the development of therapeutic DNA vaccines, has launched. The company has been created through a spin out of the powder injection DNA Vaccines technology...

Heavy drinkers are vulnerable to liver cancer despite negative viral hepatitis.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Heavy drinkers are vulnerable to liver cancer despite negative viral hepatitis. According to recent research published in the journal Hepatology Research, "alcohol has been known to be associated...

Dual electrodes and the Pringle maneuver augment liver tumor ablation.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Dual electrodes and the Pringle maneuver augment liver tumor ablation. "Several methods of liver tumor ablation have been investigated, and these include the novel technique of electrolysis....

Steatohepatitis signals insulin resistance during growth hormone therapy.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Steatohepatitis signals insulin resistance during growth hormone therapy. According to a study from the United States, "a 13 year-old boy with Prader-Willi syndrome and steatohepatitis presented...

Anti-GM3 synthase antibody enables immunodetection in human tissue.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- A novel anti-GM3 synthase antibody enables immunodetection of the enzyme in human tissue samples. In a recent study from Russia, a "[p]olyclonal antibody was raised to a cloned fragment of human...

New protein constructs stymie hepatitis D virus RNA editing.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- New protein constructs stymie hepatitis D virus RNA editing. According to a study from Taiwan, "during its life cycle, hepatitis D virus (HDV) produces two forms of delta antigen (HDAg), small...

Autophagy and enzyme activation link alpha[subscript]1-AT-deficiency to liver disease.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Autophagy and enzyme activation link alpha[subscript]1-AT-deficiency to liver disease. "Homozygous, PIZZ alpha(1)-antitrypsin (alpha(1)-AT) deficiency is associated with chronic liver disease and...

CCR5Delta32 polymorphism a risk factor for ischemic-type biliary lesions.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- CC-chemokine receptor 5Delta32 polymorphism is a risk factor for ischemic-type biliary lesions. "Ischemic-type biliary lesions are a major complication following orthotopic liver transplantation....

ACAT-1 transcripts predominate in liver and ACAT-2 predominate in the duodenum.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- ACAT-1 transcripts predominate in the liver and ACAT-2 predominate in the duodenum. "ACAT (also called sterol o-acyltransferase) catalyzes the esterification of cholesterol by reaction with...

New preclinical results show prevention of liver injury by histamine.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Maxim Pharmaceuticals (MAXM) announced preclinical results demonstrating the ability of histamine to prevent lipopolysaccharide (LPS)-induced liver injury in a rodent model. In this model,...

Publication highlights antiviral activity of NEUGENE antisense compound.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- AVI BioPharma, Inc., (AVII) announced publication of positive preclinical data relating to its NEUGENE antisense compound in the June issue of the Journal of Virology. The study, conducted in...

Viramidine 24-week data presented from chronic hepatitis C phase II trials.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Valeant Pharmaceuticals (VRX) presented detailed 24-week data from phase II clinical trials of Viramidine, a nucleoside (guanosine) analog Valeant is developing in oral form for the treatment of...

Spread of hepatitis B viruses in vitro requires extracellular progeny.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- The spread of hepatitis B viruses in vitro requires extracellular progeny and may be codetermined by polarized egress. According to recent research published in the Journal of Virology, "Viruses...

1,000 patients enrolled in phase III hepatitis C trials evaluating Zadaxin.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- SciClone Pharmaceuticals, Inc., (SCLN) announced that a total of 1,000 patients have been enrolled in its two U.S. phase III hepatitis C (HCV) clinical trials evaluating its lead product, Zadaxin. ...

Study: Nearly 30% of hepatitis C treatment candidates not receiving therapy.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- The Bruckner Group (BGI), a strategy and research firm for the pharmaceutical and biotechnology industries, announced the results of a large-scale nationwide study on hepatitis C treatment patterns...

Trial data of hepatitis C patients after liver transplantation presented.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Preliminary data from a trial comparing three immunosuppressant treatment regimens in liver transplant recipients with hepatitis C were presented at the American Transplant Congress in Boston,...

Trial results for NM283 for the treatment of HCV reported.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Idenix Pharmaceuticals, Inc., announced the results of the first human clinical trial of NM283, a novel once-daily oral treatment for hepatitis C (HCV). In a phase I/II, dose-escalation, clinical...

Hepatitis C-derived lipopeptides induced antibody-producing T cells.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Hepatitis C virus (HCV)-derived lipopeptides induced antibody-producing T lymphocytes. "We analyzed whether hepatitis C virus (HCV)-specific antibody-producing B lymphocytes can be induced in vitro...

Anti-GST autoantibody could be an early marker of autoimmune hepatitis.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Anti-GST autoantibody could be an early marker of autoimmune hepatitis. "Several phase I and phase II multi-drug metabolizing enzymes, such as CYP2D6, 3A4, and UGTA1, were reported to act as...

Virus-specific regulatory T cells counteract anti-hepatitis C virus response.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Virus-specific regulatory T cells counteract anti-hepatitis C virus response. According to published research from Italy, "regulatory T[subscript]R cells consist of phenotypically and functionally...

Hepatocellular carcinoma regresses spontaneously in some instances.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Hepatocellular carcinoma regresses spontaneously in some instances. "A case of spontaneous regression of hepatocellular carcinoma is reported and compared with the reports published in the English...

Numerical simulation model of hypothermic machine perfusion effective.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- A numerical simulation model can be used to fine-tune hypothermic machine perfusion of donated livers. "Availability of donor livers and the relatively short preservation time limit the success of...

Portal vein embolization can increase the safety of hepatic resection.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Transarterial chemoembolization (TACE) improves the survival of patients with unresectable or recurrent hepatocellular carcinoma (HCC), researchers say. "This article presents an overview of...

Hepatitis drug maker acquired.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Benitec, Ltd., announced the acquisition of Avocel, Inc., of Sunnyvale, California, an RNAi therapeutics company, and the establishment of its wholly owned U.S. subsidiary, Benitec, Inc. Through...

The N-terminal region of hepatitis C virus core protein generates nucleocapsids.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- The N-terminal region of hepatitis C virus core protein generates nucleocapsids. According to recent research from Canada, "the core (C) protein of hepatitis C virus (HCV) appears to be a...

Self-renewal capacity is a widespread property of neural crest precursor cells.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Self-renewal capacity is a widespread property of neural crest precursor cells "In vertebrates, trunk neural crest (NC) generates glia, neurons, and melanocytes. In addition, it yields...

Adult living donor liver transplantations have been slow to gain acceptance.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Adult living donor liver transplantations have been slow to gain acceptance. "Adult living donor liver transplantation (LDLT) begun in response to deceased donor organ shortage and waiting list...

Study may improve survival of transplanted livers.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- New research at the University of North Carolina (UNC) at Chapel Hill School of Medicine shows that treatment with nitric oxide after storage may dramatically improve the viability of transplanted...

LEA29Y may provide new option for preventing organ rejection.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- An investigational treatment called LEA29Y may represent a less toxic way to preserve transplanted kidney function and improve patient outcomes, according to new data presented at the American...

Lysine 72 acetylation influences hepatitis delta virus RNA synthesis.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Lysine 72 acetylation influences hepatitis delta virus RNA synthesis. According to a study from Taiwan, "hepatitis delta virus (HDV) is a single-stranded RNA virus that encodes two viral...

Hepadnavirus assembly diminishes with impaired protein glycosylation.
June 14, 2004... 2004 JUN 14 - (NewsRx.com & NewsRx.net) -- Hepadnavirus assembly diminishes with impaired protein glycosylation. "The middle surface antigen (M-sAg) of hepadnaviruses is one of three envelope proteins that share a common C-terminal S...

Mice made to express liver cell osteopontin model human autoimmune hepatitis.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Mice made to express liver cell osteopontin model human autoimmune hepatitis. "Osteopontin, a crucial factor for Th1 immune response, is expressed in stellate cells and macrophages activated in...

Nonalcoholic steatohepatitis histologically resembles alcoholic liver disease.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Non-alcoholic steatohepatitis histologically resembles alcoholic liver disease. According to a study from the United States, "forty-two patients with nonalcoholic steatohepatitis were followed for...

Genetic differences in ethnic groups affect the chronicity of hepatitis C.
June 21, 2004... 2004 JUN 21 - (NewsRx.com & NewsRx.net) -- Genetic differences in ethnic groups affect the chronicity of hepatitis C. According to recent research from the United States, "ethnic differences in the outcome of hepatitis C have been...